CN107115487A - 一种用于治疗慢性支气管炎的中药组合物及制备方法 - Google Patents
一种用于治疗慢性支气管炎的中药组合物及制备方法 Download PDFInfo
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Abstract
本发明属于中药制剂领域,目的是根据中医治疗慢性支气管炎的认识机理而提供的一种用于治疗慢性支气管炎的中药组合物,所述中药组合物的各个组分及其质量份比如下:麻黄10g、红参10g、金银花23g、芦根28g、杏仁8g、连翘22g、桔梗8g、白术12g、元胡12g、百部8g、夏枯草12g、浙贝母10g、紫菀10g、太子参14g、桑白皮12g、百合36g、五倍子6g、瓜萎12g、当归14g、鱼腥草22g、陈皮12g、板蓝根28g、细辛7g、半夏8g、合欢皮12g;本发明提供的药物是一个标本兼治的中药组方。
Description
技术领域
本发明属于中药制剂领域,具体涉及一种用于治疗慢性支气管炎的中药组合物,特别是供慢性支气管炎患者使用的中药组合物及制备方法的领域。
背景技术
祖国医学认为:慢性支气管炎是气管、支气管黏膜及周围组织的慢性非特异性炎症。临床以咳嗽、咳痰为主要症状,每年发病持续3个月,连续2年或2年以上。需要进一步排除具有咳嗽、咳痰、喘息症状的其他疾病(如肺结核、尘肺、肺脓肿、心脏病、心功能不全、支气管扩张、支气管哮喘、慢性鼻咽炎、食管反流综合征等疾患)。
那么,就如何找到一种可有效治疗慢性支气管炎的中药组合物,是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗慢性支气管炎上,人们逐渐意识到了中医治疗慢性支气管炎的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗慢性支气管炎的现状,本发明的目的是在于提供一种用于治疗慢性支气管炎的中药组合物,以解决慢性支气管炎患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述慢性支气管炎。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种用于治疗慢性支气管炎的中药组合物及制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄3~12g、红参3~12g、金银花15~30g、芦根15~35g、杏仁5~10g、连翘15~28g、桔梗5~10g、白术8~16g、元胡3~16g、百部3~10g、夏枯草9~16g、浙贝母3~12g、紫菀5~12g、太子参10~18g、桑白皮9~16g、百合15~50g、五倍子3~8g、瓜萎9~16g、当归8~18g、鱼腥草18~28g、陈皮3~15g、板蓝根15~36g、细辛3~9g、半夏3~10g、合欢皮10~16g。
一种用于治疗慢性支气管炎的中药组合物及制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄5~11g、红参6~11g、金银花18~26g、芦根18~31g、杏仁6~9g、连翘18~25g、桔梗6~9g、白术10~14g、元胡6~14g、百部5~9g、夏枯草10~14g、浙贝母6~11g、紫菀6~11g、太子参11~16g、桑白皮10~14g、百合18~42g、五倍子5~7g、瓜萎10~14g、当归10~16g、鱼腥草20~25g、陈皮6~13g、板蓝根18~31g、细辛5~8g、半夏5~9g、合欢皮11~14g。
一种用于治疗慢性支气管炎的中药组合物及制备方法,其特征在于,所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示:
麻黄10g、红参10g、金银花23g、芦根28g、杏仁8g、连翘22g、桔梗8g、白术12g、元胡12g、百部8g、夏枯草12g、浙贝母10g、紫菀10g、太子参14g、桑白皮12g、百合36g、五倍子6g、瓜萎12g、当归14g、鱼腥草22g、陈皮12g、板蓝根28g、细辛7g、半夏8g、合欢皮12g。
一种用于治疗慢性支气管炎的中药组合物及制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质和粉尘后,按照质量份比分别粉碎成粗粒状包煎;
B、将上述包好的原料中药放入冷开水中浸泡40min左右,然后再将浸泡好的药物和浸泡药物的澄清液一并放入砂锅内,注入过药60mm的冷开水进行第一次煎煮55min,滤取药液后,再次注入过药55mm的微温开水进行第二次煎煮45min,二次混合浓缩成50%的中药液440毫升备用。
一种用于治疗慢性支气管炎的中药组合物及制备方法,其特征在于,所述服用方法为:将制备好的中药液以一天服用,早晚分服,给药量220毫升/次,饭前温服。服药7~12天后,症除而愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
麻黄,性味:辛、微苦、性温,具有发汗解表、宣肺平喘、利水消肿之功效,用于治疗风寒表实证、恶寒发热、无汗、头痛身疼、邪壅于肺、肺气不宣、咳嗽气喘、风水肿、小便不利、风湿痹痛、肌肤不仁以及风疹瘙痒、阴疽痰核
红参,性味:甘、微苦、温,具有大补元气、复脉固脱、益气摄血之功效,用于治疗体虚欲脱、肢冷脉微、气不摄血、崩漏下血、心力衰竭、心原性休克;
金银花,性味:甘、寒,具有清热解毒之功效,用于治疗温病发热、热毒血痢、痈肿疔疮、喉痹及多种感染性疾病;
芦根,性味:甘、寒,具有清热生津、除烦、止呕、利尿之功效,用于治疗热病烦渴、胃热呕哕、肺热咳嗽、肺痈吐脓、热淋涩痛等病症;
杏仁,性味:苦、微温,有小毒,具有降气止咳平喘、润肠通便之功效,用于治疗咳嗽气喘、胸满痰多、血虚津枯、肠燥便秘;
连翘,性味:苦、凉,具有清热、解毒、散结、消肿之功效,用于治疗温热、丹毒、斑疹、痈疡肿毒、瘰疬、小便淋闭;
桔梗,性味:性平、味苦、辛,有小毒,具有祛痰、利咽、宣肺、排脓、利五脏、补气血、补五劳、养气之功效,用于治疗咽喉肿痛、肺痈吐脓、咳嗽痰多、痢疾腹痛、胞满胁痛、口舌生疮、赤目肿痛、小便癃闭;
白术,性味:味苦、甘、性温,具有健脾益气、燥湿利水、止汗、安胎之功效,用于治疗脾气虚弱、神疲乏力、食少少腹胀、大便溏薄、水饮内停、小便不利、水肿、痰饮眩晕、温痹酸痛、气虚自汗、胎动不安等症;
元胡,性味:味辛、苦,性温,具有活血散瘀,利气止痛之功效,用于治疗全身各部气滞血瘀之痛、痛经、经闭、症瘕、产后瘀阻、跌扑损伤、疝气作痛;
百部,性味:甘、苦、微温,有小毒,具有润肺下气止咳、杀虫之功效,用于治疗新久咳嗽、肺痨咳嗽、百日咳,外用于头虱、体虱、蛲虫病、阴痒,蜜百部润肺止咳,用于阴虚劳嗽;
夏枯草,性味:辛、苦、寒,具有清火、明目、散结、消肿之功效,用于治疗目赤肿痛、目珠夜痛、头痛眩晕、瘰疬、瘿瘤、乳痈肿痛、甲状腺肿大、淋巴结结核、乳腺增生、高血压;
浙贝母,性味:味苦、性寒,具有清热化痰、降气止咳、散结消肿之功效,用于治疗风热或痰热咳嗽、肺痈吐脓、瘰疬瘿瘤、疮痈肿毒;
紫菀,性味:辛、苦、温,具有润肺下气、消痰止咳之功效,用于治疗痰多喘咳、新久咳嗽、劳嗽咳血;
太子参,性味:甘;微苦、性微寒,具有补益脾肺、益气生津之功效,用于治疗脾胃虚弱、食欲不振、倦怠无力、气阴两伤、干咳痰少、自汗气短、以及温病后期气虚津伤、内热口渴、或神经衰弱、心悸失眠、头昏健忘、小儿夏季热;
桑白皮,性味:味甘、辛、性寒,具有泻肺平喘、利水消肿之功效,用于治疗肺热喘咳痰、水饮停肺、胀满喘急、水肿、脚气、小便不利;
百合,性味:甘、微苦、微寒,具有养阴润肺、清心安神之功效,用于治疗阴虚久嗽、痰中带血、热病后期、余热未清或情志不遂所致的虚烦惊悸、失眠多梦、精神恍惚、痈肿、湿疮等症;
五倍子,性味:酸、涩、寒,具有敛肺降火、涩肠止泻、敛汗止血、收湿敛疮之功效,用于治疗肺虚久咳、肺热痰嗽、久泻久痢、盗汗、消渴、便血痔血、外伤出血、痈肿疮毒、皮肤湿烂;
瓜萎,性味:甘、微苦、寒,具有清热涤痰、宽胸散结、润燥滑肠之功效,用于治疗肺热咳嗽、痰浊黄稠、胸痹心痛、结胸痞满、乳痈、肺痈、肠痈肿痛、大便秘结;
当归,性味:性温、味甘辛,具有补血和血、调经止痛、润燥滑肠之功效,用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的月经不调、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤;
鱼腥草,性味:辛、微寒,具有清热解毒、消痈排脓、利尿通淋之功效,用于治疗肺痈吐脓,痰热喘咳,热痢,热淋,痈肿疮毒;
陈皮,性味:味辛、苦、性温,具有理气和中,燥湿化痰,利水通便之功效,用于治疗脾胃不和、脘腹胀痛、不思饮食、呕吐哕逆、痰湿阻肺、咳嗽痰多、胸膈满闷、头目眩晕、水肿、小便不利、大便秘结、乳痈疥癣、中鱼蟹毒、酒毒等症;
板蓝根,性味:苦、寒,具有清热、解毒、凉血、利咽之功效,用于治疗温毒发斑、高热头痛、大头瘟疫、烂喉丹痧、丹毒、痄腮、喉痹、疮肿、水痘、麻疹、肝炎、流行性感冒;
细辛,性味:辛、温,具有祛风散寒、通窍止痛、温肺化饮之功效,用于治疗于风寒感冒、头痛、牙痛、鼻塞鼻渊、风湿痹痛、痰饮喘咳;
半夏,性味:辛、温,有毒,具有燥湿化痰、降逆止呕、消痞散结之功效,用于治疗痰多咳喘、痰饮眩悸、风痰眩晕、痰厥头痛、呕吐反胃、胸脘痞闷、梅核气,生用外治痈肿痰核,姜半夏多用于降逆止呕;
合欢皮,性味:甘、平,具有安神解郁、活血消痈之功效,用于治疗心神不安、忧郁、不眠、内外痈疡、跌打损伤。
本发明药物是基于中医治疗慢性支气管炎的原则,从依据慢性支气管炎的病理机制及药理作用认为:就慢性支气管炎,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述慢性支气管炎的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种用于治疗慢性支气管炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄10g、红参10g、金银花23g、芦根28g、杏仁8g、连翘22g、桔梗8g、白术12g、元胡12g、百部8g、夏枯草12g、浙贝母10g、紫菀10g、太子参14g、桑白皮12g、百合36g、五倍子6g、瓜萎12g、当归14g、鱼腥草22g、陈皮12g、板蓝根28g、细辛7g、半夏8g、合欢皮12g。
实施例2:
一种用于治疗慢性支气管炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄11g、红参11g、金银花26g、芦根31g、杏仁9g、连翘25g、桔梗9g、白术14g、元胡14g、百部9g、夏枯草14g、浙贝母11g、紫菀11g、太子参16g、桑白皮14g、百合42g、五倍子7g、瓜萎14g、当归16g、鱼腥草25g、陈皮13g、板蓝根31g、细辛8g、半夏9g、合欢皮14g。
实施例3:
一种用于治疗慢性支气管炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄12g、红参12g、金银花30g、芦根35g、杏仁10g、连翘28g、桔梗10g、白术16g、元胡16g、百部10g、夏枯草16g、浙贝母12g、紫菀12g、太子参18g、桑白皮16g、百合50g、五倍子8g、瓜萎16g、当归18g、鱼腥草28g、陈皮15g、板蓝根36g、细辛9g、半夏10g、合欢皮16g。
典型病例
经临床诊断治疗慢性支气管炎患者共2120例,年龄为42岁以上的1070例,只有1050例为42岁以下。2120例患者中痊愈的1870例,有效的250例,总有效率达100%。
Claims (3)
1.一种用于治疗慢性支气管炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄3~12g、红参3~12g、金银花15~30g、芦根15~35g、杏仁5~10g、连翘15~28g、桔梗5~10g、白术8~16g、元胡3~16g、百部3~10g、夏枯草9~16g、浙贝母3~12g、紫菀5~12g、太子参10~18g、桑白皮9~16g、百合15~50g、五倍子3~8g、瓜萎9~16g、当归8~18g、鱼腥草18~28g、陈皮3~15g、板蓝根15~36g、细辛3~9g、半夏3~10g、合欢皮10~16g。
2.根据权利要求1所述的用于治疗慢性支气管炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄5~11g、红参6~11g、金银花18~26g、芦根18~31g、杏仁6~9g、连翘18~25g、桔梗6~9g、白术10~14g、元胡6~14g、百部5~9g、夏枯草10~14g、浙贝母6~11g、紫菀6~11g、太子参11~16g、桑白皮10~14g、百合18~42g、五倍子5~7g、瓜萎10~14g、当归10~16g、鱼腥草20~25g、陈皮6~13g、板蓝根18~31g、细辛5~8g、半夏5~9g、合欢皮11~14g。
3.根据权利要求1至2所述的用于治疗慢性支气管炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄10g、红参10g、金银花23g、芦根28g、杏仁8g、连翘22g、桔梗8g、白术12g、元胡12g、百部8g、夏枯草12g、浙贝母10g、紫菀10g、太子参14g、桑白皮12g、百合36g、五倍子6g、瓜萎12g、当归14g、鱼腥草22g、陈皮12g、板蓝根28g、细辛7g、半夏8g、合欢皮12g。
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