CN107106664A - 用于调节淋巴细胞和治疗乙型肝炎病毒的ivig蛋白和kh蛋白的纯化组合物 - Google Patents
用于调节淋巴细胞和治疗乙型肝炎病毒的ivig蛋白和kh蛋白的纯化组合物 Download PDFInfo
- Publication number
- CN107106664A CN107106664A CN201580041532.2A CN201580041532A CN107106664A CN 107106664 A CN107106664 A CN 107106664A CN 201580041532 A CN201580041532 A CN 201580041532A CN 107106664 A CN107106664 A CN 107106664A
- Authority
- CN
- China
- Prior art keywords
- leu
- glu
- ser
- lys
- ala
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462003664P | 2014-05-28 | 2014-05-28 | |
| US62/003,664 | 2014-05-28 | ||
| PCT/US2015/032807 WO2015184050A1 (en) | 2014-05-28 | 2015-05-28 | Purified compositions of ivig and kh proteins for modulating lymphocytes and treating hepatitis b virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107106664A true CN107106664A (zh) | 2017-08-29 |
Family
ID=54699755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580041532.2A Pending CN107106664A (zh) | 2014-05-28 | 2015-05-28 | 用于调节淋巴细胞和治疗乙型肝炎病毒的ivig蛋白和kh蛋白的纯化组合物 |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP3148574B1 (https=) |
| JP (1) | JP2017525752A (https=) |
| CN (1) | CN107106664A (https=) |
| AU (1) | AU2015266997A1 (https=) |
| BR (1) | BR112016027818A2 (https=) |
| CA (1) | CA2949994A1 (https=) |
| ES (1) | ES2878043T3 (https=) |
| MX (1) | MX2016015574A (https=) |
| RU (1) | RU2016151761A (https=) |
| WO (1) | WO2015184050A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118878610A (zh) * | 2024-03-19 | 2024-11-01 | 北京达尔文细胞生物科技有限公司 | 一种蛋白聚合物及其生产工艺 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015184050A1 (en) | 2014-05-28 | 2015-12-03 | Rare Antibody Antigen Supply, Inc. | Purified compositions of ivig and kh proteins for modulating lymphocytes and treating hepatitis b virus |
| US20160289300A1 (en) * | 2015-04-02 | 2016-10-06 | Kieu Hoang | Method of manufacturing intravenous immunoglobulin from fraction iii |
| CN107921080A (zh) * | 2015-04-02 | 2018-04-17 | K·黄 | 由组分iii制造并纯化出用于静脉注射的凝血酶原复合物浓缩剂的方法以及治疗和预防具有抑制剂的a型血友病或感染了hiv‑1和hiv‑2的b型血友病患者的方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1673368A (zh) * | 2003-06-30 | 2005-09-28 | 弗·哈夫曼-拉罗切有限公司 | Hcv调节的蛋白表达 |
| CN102939304A (zh) * | 2010-04-09 | 2013-02-20 | 诺维信生物制药丹麦公司 | 白蛋白衍生物和变体 |
| TW201335371A (zh) * | 2012-01-31 | 2013-09-01 | Kieu Hoang | Afod及afcc之方法以及蛋白質之製備及純化方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3825429C2 (de) * | 1988-07-27 | 1994-02-10 | Biotest Pharma Gmbh | Verfahren zur Herstellung eines intravenös verabreichbaren polyklonalen Immunglobulin-Präparates mit hohem IgM-Gehalt |
| US20040142325A1 (en) * | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
| TWI489994B (zh) | 2008-03-17 | 2015-07-01 | Baxter Healthcare Sa | 供免疫球蛋白及玻尿酸酶之皮下投藥之用的組合及方法 |
| CA2639003A1 (en) | 2008-08-20 | 2010-02-20 | Canadian Blood Services | Inhibition of fc.gamma.r-mediated phagocytosis with reduced immunoglobulin preparations |
| WO2011143637A1 (en) * | 2010-05-14 | 2011-11-17 | The Regents Of The University Of Colorado, A Body Corporate | Improved complement receptor 2 (cr2) targeting groups |
| WO2015184050A1 (en) | 2014-05-28 | 2015-12-03 | Rare Antibody Antigen Supply, Inc. | Purified compositions of ivig and kh proteins for modulating lymphocytes and treating hepatitis b virus |
-
2015
- 2015-05-28 WO PCT/US2015/032807 patent/WO2015184050A1/en not_active Ceased
- 2015-05-28 JP JP2017515008A patent/JP2017525752A/ja active Pending
- 2015-05-28 RU RU2016151761A patent/RU2016151761A/ru not_active Application Discontinuation
- 2015-05-28 AU AU2015266997A patent/AU2015266997A1/en not_active Abandoned
- 2015-05-28 BR BR112016027818A patent/BR112016027818A2/pt not_active Application Discontinuation
- 2015-05-28 EP EP15799654.7A patent/EP3148574B1/en not_active Revoked
- 2015-05-28 ES ES15799654T patent/ES2878043T3/es active Active
- 2015-05-28 CN CN201580041532.2A patent/CN107106664A/zh active Pending
- 2015-05-28 MX MX2016015574A patent/MX2016015574A/es unknown
- 2015-05-28 CA CA2949994A patent/CA2949994A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1673368A (zh) * | 2003-06-30 | 2005-09-28 | 弗·哈夫曼-拉罗切有限公司 | Hcv调节的蛋白表达 |
| CN102939304A (zh) * | 2010-04-09 | 2013-02-20 | 诺维信生物制药丹麦公司 | 白蛋白衍生物和变体 |
| TW201335371A (zh) * | 2012-01-31 | 2013-09-01 | Kieu Hoang | Afod及afcc之方法以及蛋白質之製備及純化方法 |
Non-Patent Citations (2)
| Title |
|---|
| ANGELI P等: "Nephrotoxicity of Intravenous Immunoglobulin in the Setting of Liver Transplantation or HBV-related Cirrhosis: An Undervalued Topic", 《MINERVA GASTROENTEROL DIETOL》 * |
| 刘新民: "《中华医学百科大辞海 第1卷 内科学》", 31 July 2008, 军事医学科学出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118878610A (zh) * | 2024-03-19 | 2024-11-01 | 北京达尔文细胞生物科技有限公司 | 一种蛋白聚合物及其生产工艺 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2878043T3 (es) | 2021-11-18 |
| EP3148574A4 (en) | 2017-04-05 |
| MX2016015574A (es) | 2018-05-28 |
| RU2016151761A (ru) | 2018-07-03 |
| CA2949994A1 (en) | 2015-12-03 |
| WO2015184050A1 (en) | 2015-12-03 |
| EP3148574B1 (en) | 2021-04-14 |
| JP2017525752A (ja) | 2017-09-07 |
| AU2015266997A1 (en) | 2016-12-08 |
| BR112016027818A2 (pt) | 2017-10-24 |
| RU2016151761A3 (https=) | 2018-12-26 |
| EP3148574A1 (en) | 2017-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170829 |