BR112016027818A2 - composições purificadas de proteínas ivig e kh para modular linfócitos e tratar virus da hepatite b. - Google Patents
composições purificadas de proteínas ivig e kh para modular linfócitos e tratar virus da hepatite b.Info
- Publication number
- BR112016027818A2 BR112016027818A2 BR112016027818A BR112016027818A BR112016027818A2 BR 112016027818 A2 BR112016027818 A2 BR 112016027818A2 BR 112016027818 A BR112016027818 A BR 112016027818A BR 112016027818 A BR112016027818 A BR 112016027818A BR 112016027818 A2 BR112016027818 A2 BR 112016027818A2
- Authority
- BR
- Brazil
- Prior art keywords
- virus
- cells
- blood plasma
- plasma products
- protein compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
a presente invenção se refere a produtos de plasma sanguíneo purificados obtidos de fração ii+iii contendo proteínas em concentrações úteis para o tratamento de várias doenças e infecções incluindo vírus da hepatite b. também são descritos métodos de fabricação e tratamento. os produtos purificados de plasma de sangue regulam níveis de células imunes e suas proteínas nos órgãos e sangue periférico dos indivíduos tratados. exemplos de células imunes e proteínas associadas reguladas pelos produtos purificados de plasma de sangue incluem níveis de cd62l em células t, células t cd4+, cd8+, cd28+ e foxp3+, bem como granulócitos e macrófagos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462003664P | 2014-05-28 | 2014-05-28 | |
PCT/US2015/032807 WO2015184050A1 (en) | 2014-05-28 | 2015-05-28 | Purified compositions of ivig and kh proteins for modulating lymphocytes and treating hepatitis b virus |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112016027818A2 true BR112016027818A2 (pt) | 2017-10-24 |
Family
ID=54699755
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016027818A BR112016027818A2 (pt) | 2014-05-28 | 2015-05-28 | composições purificadas de proteínas ivig e kh para modular linfócitos e tratar virus da hepatite b. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP3148574B1 (pt) |
JP (1) | JP2017525752A (pt) |
CN (1) | CN107106664A (pt) |
AU (1) | AU2015266997A1 (pt) |
BR (1) | BR112016027818A2 (pt) |
CA (1) | CA2949994A1 (pt) |
ES (1) | ES2878043T3 (pt) |
MX (1) | MX2016015574A (pt) |
RU (1) | RU2016151761A (pt) |
WO (1) | WO2015184050A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015184050A1 (en) | 2014-05-28 | 2015-12-03 | Rare Antibody Antigen Supply, Inc. | Purified compositions of ivig and kh proteins for modulating lymphocytes and treating hepatitis b virus |
WO2016161422A1 (en) * | 2015-04-02 | 2016-10-06 | Kieu Hoang | A method of manufacturing and purifiying prothrombin complex concentrate from fraction iii for intraveneous injection and a method of curing and preventing hemophilia a with inhibitors or hempophilia b patients infected with hiv-1 and hiv-2 |
US20160289300A1 (en) * | 2015-04-02 | 2016-10-06 | Kieu Hoang | Method of manufacturing intravenous immunoglobulin from fraction iii |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3825429C2 (de) * | 1988-07-27 | 1994-02-10 | Biotest Pharma Gmbh | Verfahren zur Herstellung eines intravenös verabreichbaren polyklonalen Immunglobulin-Präparates mit hohem IgM-Gehalt |
US20040142325A1 (en) * | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
GB0315248D0 (en) * | 2003-06-30 | 2003-08-06 | Hoffmann La Roche | HCV regulated protein expression |
TWI532498B (zh) * | 2008-03-17 | 2016-05-11 | 巴克斯特保健公司 | 供免疫球蛋白及玻尿酸酶之皮下投藥之用的組合及方法 |
CA2639003A1 (en) | 2008-08-20 | 2010-02-20 | Canadian Blood Services | Inhibition of fc.gamma.r-mediated phagocytosis with reduced immunoglobulin preparations |
KR20130070576A (ko) * | 2010-04-09 | 2013-06-27 | 노보자임스 바이오파마 디케이 에이/에스 | 알부민 유도체 및 변이체 |
EP2569332B1 (en) * | 2010-05-14 | 2019-01-09 | The Regents of the University of Colorado, A Body Corporate | Improved complement receptor 2 (cr2) targeting groups |
WO2015184050A1 (en) | 2014-05-28 | 2015-12-03 | Rare Antibody Antigen Supply, Inc. | Purified compositions of ivig and kh proteins for modulating lymphocytes and treating hepatitis b virus |
TW201335181A (zh) | 2012-01-31 | 2013-09-01 | Kieu Hoang | 55種新發現的蛋白質之序列及其應用 |
-
2015
- 2015-05-28 WO PCT/US2015/032807 patent/WO2015184050A1/en active Application Filing
- 2015-05-28 AU AU2015266997A patent/AU2015266997A1/en not_active Abandoned
- 2015-05-28 ES ES15799654T patent/ES2878043T3/es active Active
- 2015-05-28 RU RU2016151761A patent/RU2016151761A/ru not_active Application Discontinuation
- 2015-05-28 MX MX2016015574A patent/MX2016015574A/es unknown
- 2015-05-28 BR BR112016027818A patent/BR112016027818A2/pt not_active Application Discontinuation
- 2015-05-28 CN CN201580041532.2A patent/CN107106664A/zh active Pending
- 2015-05-28 CA CA2949994A patent/CA2949994A1/en active Pending
- 2015-05-28 EP EP15799654.7A patent/EP3148574B1/en not_active Revoked
- 2015-05-28 JP JP2017515008A patent/JP2017525752A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2015184050A1 (en) | 2015-12-03 |
JP2017525752A (ja) | 2017-09-07 |
ES2878043T3 (es) | 2021-11-18 |
CA2949994A1 (en) | 2015-12-03 |
AU2015266997A1 (en) | 2016-12-08 |
RU2016151761A (ru) | 2018-07-03 |
MX2016015574A (es) | 2018-05-28 |
CN107106664A (zh) | 2017-08-29 |
EP3148574B1 (en) | 2021-04-14 |
EP3148574A4 (en) | 2017-04-05 |
RU2016151761A3 (pt) | 2018-12-26 |
EP3148574A1 (en) | 2017-04-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B04C | Request for examination: application reinstated [chapter 4.3 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001 |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |