CN107074967B - 白介素-2/白介素-2受体α融合蛋白和使用方法 - Google Patents

白介素-2/白介素-2受体α融合蛋白和使用方法 Download PDF

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CN107074967B
CN107074967B CN201580042330.XA CN201580042330A CN107074967B CN 107074967 B CN107074967 B CN 107074967B CN 201580042330 A CN201580042330 A CN 201580042330A CN 107074967 B CN107074967 B CN 107074967B
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fusion protein
activity
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amino acid
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CN107074967A (zh
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T.马列克
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University of Miami
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag

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CN201580042330.XA 2014-08-06 2015-08-05 白介素-2/白介素-2受体α融合蛋白和使用方法 Active CN107074967B (zh)

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US201462033726P 2014-08-06 2014-08-06
US62/033726 2014-08-06
PCT/US2015/043792 WO2016022671A1 (en) 2014-08-06 2015-08-05 Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use

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EP3177307A1 (en) 2017-06-14
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WO2016022671A1 (en) 2016-02-11
PT3177307T (pt) 2024-09-13
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ZA201700245B (en) 2024-06-26
JP7272663B2 (ja) 2023-05-12
US20230079120A1 (en) 2023-03-16
JP2017523789A (ja) 2017-08-24
EA202091342A2 (ru) 2020-11-30
SG11201700706WA (en) 2017-02-27
AU2020203352B2 (en) 2022-03-10
LT3177307T (lt) 2024-08-12
CO2017002166A2 (es) 2017-05-19
HRP20241258T1 (hr) 2024-12-06
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