CN107050455B - 用于治疗中枢介导的恶心及呕吐的组合物及方法 - Google Patents
用于治疗中枢介导的恶心及呕吐的组合物及方法 Download PDFInfo
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- CN107050455B CN107050455B CN201610795817.1A CN201610795817A CN107050455B CN 107050455 B CN107050455 B CN 107050455B CN 201610795817 A CN201610795817 A CN 201610795817A CN 107050455 B CN107050455 B CN 107050455B
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| EP2722045B1 (en) | 2009-11-18 | 2016-07-06 | Helsinn Healthcare SA | Compositions for treating centrally mediated nausea and vomiting |
| PE20121483A1 (es) | 2009-11-18 | 2012-12-02 | Helsinn Healthcare Sa | Composiciones para tratar nausea y vomito centralmente mediados |
| WO2013004766A1 (en) * | 2011-07-04 | 2013-01-10 | Ferrari Giulio | Nk-1 receptor antagonists for treating corneal neovascularisation |
| WO2013057554A2 (en) * | 2011-10-18 | 2013-04-25 | Helsinn Healthcare Sa | Therapeutic combinations of netupitant and palonosetron |
| US9403772B2 (en) | 2011-11-29 | 2016-08-02 | Helsinn Healthcare Sa | 4-(5-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-4-(o-tolyl)pyridin-2-yl)-1-methyl-1-((phosphonooxy)methyl)piperazin-1-ium as a neurokinin receptor modulator |
| US8426450B1 (en) | 2011-11-29 | 2013-04-23 | Helsinn Healthcare Sa | Substituted 4-phenyl pyridines having anti-emetic effect |
| CN103520725B (zh) * | 2012-07-05 | 2017-10-24 | 海思科医药集团股份有限公司 | 一种治疗呕吐的药物组合物 |
| RU2770050C2 (ru) | 2015-03-04 | 2022-04-14 | Ванда Фармасьютиклз Инк. | Способ лечения с применением традипитанта |
| CN106902086B (zh) * | 2015-12-23 | 2020-10-20 | 江苏恒瑞医药股份有限公司 | 一种包含奈妥匹坦的固体组合物 |
| GB201618425D0 (en) * | 2016-11-01 | 2016-12-14 | Acacia Pharma Ltd | method |
| GB201702250D0 (en) | 2017-02-10 | 2017-03-29 | Acacia Pharma Ltd | Method |
| CN108721214B (zh) * | 2017-04-14 | 2020-06-16 | 和龙 | 奈妥吡坦和帕洛诺司琼复方纳米粒溶液、纳米粒及制备方法和用途 |
| CN108853010A (zh) * | 2017-05-15 | 2018-11-23 | 和龙 | 奈妥吡坦环糊精包合物、复方组合制剂及其制备方法和用途 |
| CN109200018A (zh) * | 2017-07-04 | 2019-01-15 | 南京诺瑞特医药科技有限公司 | 含有奈妥吡坦的微乳制剂 |
| DK3710000T3 (da) * | 2017-11-17 | 2025-06-16 | Vanda Pharmaceuticals Inc | Tradipitant til anvendelse til behandling af gastroparese |
| WO2019148247A1 (en) * | 2018-02-02 | 2019-08-08 | Eustralis Pharmaceuticals Limited (Trading As Pressura Neuro) | Oral formulations and uses thereof |
| JP2024501994A (ja) * | 2020-12-25 | 2024-01-17 | 上海盛迪医▲葯▼有限公司 | Ｎｋ１拮抗剤プロドラッグ化合物と５－ｈｔ３受容体拮抗剤との併用使用 |
| EP4385500B1 (en) | 2022-12-12 | 2026-07-01 | Alfred E. Tiefenbacher (GmbH & Co. KG) | FIXED-DOSE COMBINATION INCLUDING NETUPITANT AND PALONOSETRON |
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| EP4385497A1 (en) | 2022-12-12 | 2024-06-19 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Antioxidant-free fixed dose combination of netupitant and palonosetron |
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| WO2025246530A1 (en) * | 2024-05-30 | 2025-12-04 | The Chinese University Of Hong Kong | Personalized anti-emetic treatment for chemotherapy-induced nausea and vomiting |
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