HK1214147A1 - 用於治疗中枢介导的恶心及呕吐的组合物及方法 - Google Patents

用於治疗中枢介导的恶心及呕吐的组合物及方法 Download PDF

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Publication number
HK1214147A1
HK1214147A1 HK16102109.6A HK16102109A HK1214147A1 HK 1214147 A1 HK1214147 A1 HK 1214147A1 HK 16102109 A HK16102109 A HK 16102109A HK 1214147 A1 HK1214147 A1 HK 1214147A1
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HK
Hong Kong
Prior art keywords
netupitant
palonosetron
capsule
nausea
vomiting
Prior art date
Application number
HK16102109.6A
Other languages
English (en)
Chinese (zh)
Inventor
‧特蘭托
F‧特兰托
‧坎托雷吉
S‧坎托雷吉
‧羅西
G‧罗西
‧坎內拉
R‧坎内拉
‧邦那迪奧
D‧邦那迪奥
‧布拉利亞
R‧布拉利亚
Original Assignee
赫尔森保健股份公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43608757&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1214147(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 赫尔森保健股份公司 filed Critical 赫尔森保健股份公司
Publication of HK1214147A1 publication Critical patent/HK1214147A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Paints Or Removers (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)
HK16102109.6A 2009-11-18 2016-02-24 用於治疗中枢介导的恶心及呕吐的组合物及方法 HK1214147A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26247009P 2009-11-18 2009-11-18
US61/262,470 2009-11-18
US38270910P 2010-09-14 2010-09-14
US61/382,709 2010-09-14

Publications (1)

Publication Number Publication Date
HK1214147A1 true HK1214147A1 (zh) 2016-07-22

Family

ID=43608757

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16102109.6A HK1214147A1 (zh) 2009-11-18 2016-02-24 用於治疗中枢介导的恶心及呕吐的组合物及方法
HK16102110.3A HK1214148A1 (zh) 2009-11-18 2016-02-24 用於治疗中枢介导的恶心及呕吐的组合物及方法

Family Applications After (1)

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HK16102110.3A HK1214148A1 (zh) 2009-11-18 2016-02-24 用於治疗中枢介导的恶心及呕吐的组合物及方法

Country Status (40)

Country Link
US (1) US12042494B2 (enExample)
EP (3) EP2722044B1 (enExample)
JP (1) JP5890780B2 (enExample)
KR (1) KR101615108B1 (enExample)
CN (6) CN107050455B (enExample)
AP (1) AP3083A (enExample)
AU (1) AU2010320598B2 (enExample)
BR (1) BR112012011485B1 (enExample)
CA (1) CA2778301C (enExample)
CL (1) CL2012001276A1 (enExample)
CO (1) CO6551693A2 (enExample)
CR (1) CR20120216A (enExample)
CU (1) CU24048B1 (enExample)
CY (1) CY1118062T1 (enExample)
DK (2) DK2722045T3 (enExample)
DO (1) DOP2012000138A (enExample)
EA (1) EA026815B1 (enExample)
EC (1) ECSP12011907A (enExample)
ES (4) ES2559475T3 (enExample)
GE (1) GEP20156226B (enExample)
GT (1) GT201200156A (enExample)
HK (2) HK1214147A1 (enExample)
HR (3) HRP20140759T1 (enExample)
HU (1) HUE029677T2 (enExample)
IL (1) IL219576A (enExample)
LT (1) LT2722045T (enExample)
MA (1) MA33810B1 (enExample)
MX (1) MX2012005347A (enExample)
MY (1) MY159393A (enExample)
NI (1) NI201200090A (enExample)
NZ (1) NZ599439A (enExample)
PE (1) PE20121483A1 (enExample)
PH (1) PH12012500887A1 (enExample)
PL (3) PL2722044T3 (enExample)
PT (2) PT2722045T (enExample)
RS (2) RS53491B1 (enExample)
SI (2) SI2722045T1 (enExample)
SM (1) SMT201400112B (enExample)
TN (1) TN2012000170A1 (enExample)
WO (1) WO2011061622A1 (enExample)

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RU2770050C2 (ru) 2015-03-04 2022-04-14 Ванда Фармасьютиклз Инк. Способ лечения с применением традипитанта
CN106902086B (zh) * 2015-12-23 2020-10-20 江苏恒瑞医药股份有限公司 一种包含奈妥匹坦的固体组合物
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CN108853010A (zh) * 2017-05-15 2018-11-23 和龙 奈妥吡坦环糊精包合物、复方组合制剂及其制备方法和用途
CN109200018A (zh) * 2017-07-04 2019-01-15 南京诺瑞特医药科技有限公司 含有奈妥吡坦的微乳制剂
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JP2024501994A (ja) * 2020-12-25 2024-01-17 上海盛迪医▲葯▼有限公司 Ｎｋ１拮抗剤プロドラッグ化合物と５－ｈｔ３受容体拮抗剤との併用使用
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AP3083A (en) 2015-01-31
US20230263799A1 (en) 2023-08-24
CA2778301A1 (en) 2011-05-26
PE20121483A1 (es) 2012-12-02
CN107050455B (zh) 2020-09-29
HUE029677T2 (hu) 2017-03-28
BR112012011485B1 (pt) 2021-06-29
EP2361090A1 (en) 2011-08-31
EP2722044A1 (en) 2014-04-23
CN106512010A (zh) 2017-03-22
ES2623503T3 (es) 2017-07-11
NI201200090A (es) 2012-11-13
CR20120216A (es) 2012-07-24
TN2012000170A1 (en) 2013-12-12
PL2722045T3 (pl) 2017-03-31
EP2722044B1 (en) 2017-01-04
BR112012011485A2 (pt) 2018-04-03
CN102655864A (zh) 2012-09-05
KR20120101456A (ko) 2012-09-13
CU20120078A7 (es) 2012-10-15
CU24048B1 (es) 2014-12-26
ES2595077T3 (es) 2016-12-27
JP5890780B2 (ja) 2016-03-22
HRP20140759T1 (hr) 2014-10-24
PL2722044T3 (pl) 2017-08-31
CN107050455A (zh) 2017-08-18
CA2778301C (en) 2016-06-14
DK2722045T3 (en) 2016-10-24
EA026815B1 (ru) 2017-05-31
DOP2012000138A (es) 2012-11-15
CL2012001276A1 (es) 2012-12-07
SMT201400112B (it) 2014-11-10
ES2559475T3 (es) 2016-02-12
MY159393A (en) 2016-12-30
IL219576A (en) 2017-08-31
RS53491B1 (sr) 2015-02-27
GT201200156A (es) 2014-03-27
EP2727590A1 (en) 2014-05-07
LT2722045T (lt) 2016-09-26
WO2011061622A1 (en) 2011-05-26
CN104856998A (zh) 2015-08-26
CN106421793B (zh) 2023-06-16
AP2012006278A0 (en) 2012-06-30
US12042494B2 (en) 2024-07-23
SI2722045T1 (sl) 2017-02-28
PT2361090E (pt) 2014-09-03
IL219576A0 (en) 2012-06-28
PH12012500887A1 (en) 2016-08-26
SI2361090T1 (sl) 2014-09-30
JP2013511507A (ja) 2013-04-04
CO6551693A2 (es) 2012-10-31
NZ599439A (en) 2014-06-27
CN106421793A (zh) 2017-02-22
DK2361090T3 (da) 2014-08-25
KR101615108B1 (ko) 2016-05-12
CN104856999A (zh) 2015-08-26
ES2494015T3 (es) 2014-09-12
PT2722045T (pt) 2016-10-18
GEP20156226B (en) 2015-01-26
HRP20170419T1 (hr) 2017-06-02
MA33810B1 (fr) 2012-12-03
ECSP12011907A (es) 2012-10-30
EP2361090B1 (en) 2014-05-21
RS55206B1 (sr) 2017-01-31
CY1118062T1 (el) 2017-06-28
HRP20161277T1 (hr) 2016-11-18
MX2012005347A (es) 2012-08-03
HK1214148A1 (zh) 2016-07-22
PL2361090T3 (pl) 2014-10-31
EP2727590B1 (en) 2015-10-21
AU2010320598B2 (en) 2016-06-16
EA201290356A1 (ru) 2012-12-28
AU2010320598A1 (en) 2012-06-14

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