CN107029099A - A kind of relieving cough and asthma Chinese medicine composition and preparation method - Google Patents

A kind of relieving cough and asthma Chinese medicine composition and preparation method Download PDF

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CN107029099A
CN107029099A CN201710219567.1A CN201710219567A CN107029099A CN 107029099 A CN107029099 A CN 107029099A CN 201710219567 A CN201710219567 A CN 201710219567A CN 107029099 A CN107029099 A CN 107029099A
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asthma
cough
chinese medicine
medicine composition
maltodextrin
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魏增强
罗社文
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Abstract

The present invention provides a kind of relieving cough and asthma Chinese medicine composition and preparation method, and the Chinese medicine composition is composed of the following components by mass percentage:Momordica grosvenori 5%~7%, Exocarpium Citri Rubrum 5%~7%, Chinese torreyanut 5%~7%, the sophora bud 5%~7%, purple perilla seed 5%~7%, balloonflower root 5%~7%, gingko 7%~9%, Chinese yam 8%~10%, lily 8%~10%, emblic 5%~7%, the sterculia seed 5%~7%, almond 7%~9%, dried orange peel 4%~6%, cordate houttuynia 5%~7%, honeysuckle 3%~5%, Buddha's hand 4%~6%.Will above-mentioned component mix after add water be boiled into after paste with maltodextrin and potassium sorbate mixing granulation, dry, sterilizing,.The present invention plays the role of relieving cough and reducing sputum, inducing diaphoresis of relievining asthma, and the property of medicine is gentle, has no toxic side effect, is to treat both principal and secondary aspect of disease the characteristics of most prominent, long-term effect is good, and recurrence rate is low, has preferable therapeutic effect to the prolonged and repeated infection of the upper respiratory tract, cough, asthma.

Description

A kind of relieving cough and asthma Chinese medicine composition and preparation method
Technical field
The invention belongs to the Chinese medicine composition of integration of drinking and medicinal herbs category, and in particular to a kind of relieving cough and asthma Chinese medicine composition and Preparation method.
Background technology
The opinion of cough and asthma is started from《Interior warp》,《Plain Questions coughs opinion》Cloud:" the making us of lung coughs, He YeQi uncle is to saying:The vital organs of the human body All make us coughing, non-only lung.”《Bier five, which reads five, to be made》Cloud:" lung patient dyspnea and flaring of nares ".《The big paradoxia of Plain Questions》Cloud:" lung it Heap soil or fertilizer over and around the roots is breathed heavily and turgor ".The sick position of the cause of disease and the symptom of cough and asthma is more discussed in detail, it is indicated that vital organs of the human body functional disturbance is involved in lung, It may occur in which cough and asthma.Cough and also known as cough, breathe heavily and also known as pant, stridulate, breathing heavily inverse, upper gas etc., be the cardinal symptom performance of lung system disease.Outside Feel six evil, internal organs internal injury causes functional disturbance, involved in lung, causes impairment of dispersing and descending function of the lung, Lung Qi upward reversal, then can occur or cough or Breathe heavily or cough and asthma Symptoms.Breathe heavily has cough mostly, coughs not necessarily with breathing heavily, and so coughs and breathes heavily not from lung, does not also terminate in Lung, its common interpretation of the cause, onset and process of an illness is existed " Lung Qi upward reversal ".Thus, cough and asthma is the cardinal symptom of tuberculosis.
The Western medicine for the treatment of cough and asthma is treated primarily directed to cell, the spy relievingd asthma by force, rapidly with markedly fast, lethality Point, for example:Terbutaline, ketelin capsule, Zhejiang Kang Enbei P-Cymenes, Chongqing Ge Lan element ventolin inhaler, aminophylline, Albuterol, carbocisteine, cough-stopping (Ke Ke) capsule etc..But toxic side effect is larger, the organs such as liver, kidney can be damaged, part Western medicine is very To having drug resistance, largely it is not suitable for long-term taking, so most of patients is more likely to select Chinese medicine.Treated on existing market The Chinese medicine of cough and asthma has a lot, although these medicines can be relieving cough and asthma in time, cures the symptoms, not the disease, the state of an illness easily recurs.
The content of the invention
It is an object of the invention to provide a kind of relieving cough and asthma Chinese medicine composition, using the treatment means of solid decoction of medicinal ingredients, use In the prolonged and repeated infection of the upper respiratory tract, cough, the treatment of asthma, with having no toxic side effect, the spy that cure rate is high, recurrence rate is low Point.
The technical solution adopted in the present invention is,
A kind of relieving cough and asthma Chinese medicine composition, it is by mass percentage, raw materials used composed of the following components:
Momordica grosvenori 5%~7%, Exocarpium Citri Rubrum 5%~7%, Chinese torreyanut 5%~7%, the sophora bud 5%~7%, purple perilla seed 5%~7%, Balloonflower root 5%~7%, gingko 7%~9%, Chinese yam 8%~10%, lily 8%~10%, emblic 5%~7%, the sterculia seed 5%~7%, almond 7%~9%, dried orange peel 4%~6%, cordate houttuynia 5%~7%, honeysuckle 3%~5%, Buddha's hand 4%~ 6%, the mass percent summation of above each component is 100%.
The preparation method of above-mentioned relieving cough and asthma Chinese medicine composition, including following operating procedure:
Step 1,
By mass percentage, weigh Momordica grosvenori 5%~7%, Exocarpium Citri Rubrum 5%~7%, Chinese torreyanut 5%~7%, the sophora bud 5%~ 7%th, purple perilla seed 5%~7%, balloonflower root 5%~7%, gingko 7%~9%, Chinese yam 8%~10%, lily 8%~10%, emblic Son 5%~7%, the sterculia seed 5%~7%, almond 7%~9%, dried orange peel 4%~6%, cordate houttuynia 5%~7%, honeysuckle 3% ~5%, Buddha's hand 4%~6%, the mass percent summation of above each component is 100%;
Step 2,
16 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts are decocted 2 hours, are added for the second time The water of 6 times of amounts, is decocted 2 hours, merges decocting liquid twice, filtering, it is 1.20~1.40 (60 DEG C) that filtrate, which is concentrated into relative density, Thick paste;
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby;
Step 4,
By mass percentage, thick paste 24%~26.97%, the and of maltodextrin 73%~75.97% that step 1 is obtained are weighed Potassium sorbate 0.01%~0.03%, the mass percent summation of above each component is 100%;Thick paste and water are stirred To whitewashing, the weight ratio of thick paste and water is 1:2;
Step 5,
In multifunctional fluidized bed, maltodextrin and potassium sorbate are subjected to material heating and premixed, mixed material is obtained, so Pelletized afterwards toward whitewashing on mixed material, finally dry, cool, discharging, shutdown;
Step 6,
Last whole grain and filling, is produced.
In above-mentioned steps 5, by maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 15m3/ h~ 25m3/ h, EAT is set to 80 DEG C~100 DEG C, heating premix is carried out to material 7~15 minutes, obtains mixed material;In advance It is mixed finish after, by adjusting air quantity and EAT so that mixed material temperature reaches 35 DEG C~40 DEG C, then multi-functional fluidisation Bed starts whitewashing, and spouting velocity is set to 15rpm~20rpm, and atomizing pressure is 1.50bar~2.0bar, due to thing after whitewashing Material is aggravated, temperature reduction, and air quantity is adjusted at any time and keeps material fully to jump, and regulation EAT keeps temperature of charge at any time At 35 DEG C~40 DEG C, whitewashing is closed after whitewashing 15min~30min, granulation is completed;Multifunctional fluidized bed EAT is set again It is set to 100 DEG C material is dried, regulation air quantity keeps material fully to jump, when the moisture≤2.0% of material, by air intake Temperature is down to 25 DEG C~45 DEG C, the temperature of material is reduced to 25 DEG C~45 DEG C, finally discharging shutdown.
In above-mentioned steps 6, the particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 is completed The dry particl of selection, is then fitted into bag and completes filling by whole grain.
The beneficial effects of the invention are as follows:There is relieving cough and reducing sputum, inducing diaphoresis of relievining asthma, the property of medicine is gentle, has no toxic side effect, most prominent The characteristics of going out is to treat both principal and secondary aspect of disease, and long-term effect is good, and recurrence rate is low, is had preferably to the prolonged and repeated infection of the upper respiratory tract, cough, asthma Therapeutic effect.
Embodiment
The present invention provides a kind of relieving cough and asthma Chinese medicine composition, by mass percentage, raw materials used by following components group Into:
Momordica grosvenori 5%~7%, Exocarpium Citri Rubrum 5%~7%, Chinese torreyanut 5%~7%, the sophora bud 5%~7%, purple perilla seed 5%~7%, Balloonflower root 5%~7%, gingko 7%~9%, Chinese yam 8%~10%, lily 8%~10%, emblic 5%~7%, the sterculia seed 5%~7%, almond 7%~9%, dried orange peel 4%~6%, cordate houttuynia 5%~7%, honeysuckle 3%~5%, Buddha's hand 4%~ 6%, the mass percent summation of above each component is 100%.
The pharmacological action of Chinese medicine of the present invention is as follows:
Momordica grosvenori:Sweet, cool, return lung large intestine channel clearing heat and moistening lung, relieving sore-throat opens sound, laxation defaecation, for lung-heat type cough, pharyngalgia mistake Sound, dry constipation of intestines.
Exocarpium Citri Rubrum:Regulating the flow of QI to ease the stomach, eliminating dampness and eliminating phlegm, for coughing with a lot of sputum, dyspepsia is got sick from drinking too much wine, and evil of vomitting ruffian is vexed.
Chinese torreyanut:Killing insect and eliminating accumulation, moistens the lung and relieve the cough, moistening dryness for relaxing bowels, and for hookworm disease, roundworm disease, taeniasis, abdominal pain due to enterositosis is small Youngster's infantile malnutrition due to digestive disturbances or intestinalparasites, xeropulmonary cough, constipation.
The sophora bud:Cooling blood and hemostasis, clearing liver-fire, for having blood in stool, hemorrhoid blood, bloody flux, uterine bleeding is spitted blood, and the hot hot eyes of liver is had a headache dizzy It is dizzy.
Purple perilla seed:Relieving exterior syndrome and dispelling cold, relieving QI stagnancy in the stomach, for anemofrigid cold, cough evil of vomitting, the vomiting of pregnancy, fish and crab poisoning sending down abnormally ascending Resolving sputum, only phlegm relieving asthma, relax bowel, for phlegm stops up the circulation of vital energy in the wrong direction, cough and asthma, dry constipation of intestines.
Balloonflower root:Facilitaing lung, relieving sore-throat, eliminating the phlegm, apocenosis, for coughing with a lot of sputum, uncomfortable in chest not smooth, pharyngalgia sound is mute, lung carbuncle pyemesis.
Gingko:It is sweet, it is bitter, it is puckery, put down, poisonous, return lung kidney channel astringing lung for relieving asthma, stop-band contracting urine is breathed with cough for abundant expectoration, with lower white It is turbid, enuresis frequent micturition.
Chinese yam:It is sweet, put down, return skin lung kidney channel tonifying spleen nourishing the stomach, engender liquid and benefic lung, for spleen eating less, endless diarrhea, the deficiency syndrome of the lung is breathed heavily Cough, emission due to the kidney deficiency, under band, frequent micturition, abnormal heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) good efficacy to suffering from a deficiency of the kidney;For spleen eating less, diarrhea loose stool, leukorrhea mistake It is many.
Lily:It is sweet, tremble with fear, thoughts of returning home lung channel Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing, for deficiency of Yin cough caused by dryness, consumptive disease is coughed hemoptysis, dysphoria palpitates with fear, Insomnia and dreamful sleep, it is absent-minded.
Emblic:Sweet, sour and astringent, cool, return lung stomach clearing heat and cooling blood, food digesting stomach fortifying, cough-relieving of promoting the production of body fluid, for blood-head blood stasis, disappears Change bad, abdominal distension, cough, laryngalgia, dry.
The sterculia seed:Clearing heat and moistening lung, relieving sore-throat opens sound, relaxes bowel.For lung heat celostomia, dry cough without phlegm, pharyngodynia with dryness, thermojunction Just close, headache and hot eyes.
Almond:Hardship, trembles with fear, poisonous.Return liver taste treat moss through desinsection, for roundworm disease, around parasitosis, outer Zhi Jie Xian itch.
Dried orange peel:Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For abdominal fullness and distention, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
Cordate houttuynia:It is pungent, it is slightly cold, return lung is through clearing heat and detoxicating, the carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia, and for lung carbuncle pyemesis, phlegm heat is coughed Breathe heavily, hot dysentery, heat gonorrhea, carbuncle sore tumefacting virus.
Honeysuckle:It is sweet, tremble with fear, return lung heart stomach is clearing heat and detoxicating, dispelling wind and heat from the body, for carbuncle swells furunculosis, larynx numbness, erysipelas, heat toxin Bloody flux, anemopyretic cold, warm disease heating.
Buddha's hand:It is pungent, bitter, acid, temperature, Return liver taste lung channel dispersing stagnated hepatoqi, and stomach and alleviating pain, it is eliminating dampness and eliminating phlegm, for stagnation of liver-QI and stomach-QI, Distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, deficiency of food vomiting, coughing with a lot of sputum.
The old multifactor body abundant expectoration of cough and asthma with the passing of time, accumulation phlegm-heat in the interior, caused by the failure of the kidney in receiving air.Suitable clearing lung and eliminating phlegm is controlled, it is relieving cough and asthma, Gu Kidney receives gas.According to《Chinese Pharmacopoeia》, almond facilitaing lung dissipates heresy to relieving asthma in side, gingko astringing lung for relieving asthma and eliminating the phlegm, is altogether monarch, one dissipates one Receive, strengthen the work(relievingd asthma.Momordica grosvenori, purple perilla seed, Exocarpium Citri Rubrum, balloonflower root, Buddha's hand, dried orange peel, qi-regulating are relievingd asthma, cough-relieving apophlegmatic, are altogether minister.Fish Raw meat grass, honeysuckle, Chinese torreyanut, the sophora bud, lily, emblic, the sterculia seed, clear purging the lung of pathogenic fire heat is relieving cough and asthma;Chinese yam, it is sour and astringent to reinforce the kidney, receive gas Relieving asthma;Cordate houttuynia, honeysuckle, Chinese torreyanut, the sophora bud, lily, emblic, the sterculia seed, Chinese yam, are altogether assistant.All medicines share, makes lung qi respectful Drop, phlegm is warm clearly, and kidney qi must be consolidated, then all diseases of dyspnea and cough with excessive sputum are removed certainly.
Chinese medicine composition of the present invention is by the way of oral, oral 10 grams every time, 2 times a day, is within one month a course for the treatment of.
With reference to specific embodiment, the present invention is described in detail.
Embodiment 1
A kind of preparation method of relieving cough and asthma Chinese medicine composition, including following operating procedure:
Step 1,
Weigh Momordica grosvenori 5kg, Exocarpium Citri Rubrum 7kg, Chinese torreyanut 6kg, sophora bud 7kg, purple perilla seed 5kg, balloonflower root 7kg, gingko 7kg, Chinese yam 8kg, lily 8kg, emblic 5kg, sterculia seed 7kg, almond 9kg, dried orange peel 4kg, cordate houttuynia 6kg, honeysuckle 3kg, Buddha's hand 6kg;
Step 2,
16 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts are decocted 2 hours, are added for the second time The water of 6 times of amounts, is decocted 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.35 (60 DEG C);
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby;
Step 4,
Weigh thick paste 20.5kg, maltodextrin 61.5kg and potassium sorbate 20g;Thick paste and water are uniformly mixing to obtain spray The weight ratio of slurry, thick paste and water is 1:2;
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 20m3/ h, EAT is set For 90 DEG C, heating premix is carried out to material 10 minutes, obtain mixed material;After premix is finished, by adjusting air quantity and entering wind-warm syndrome Degree so that mixed material temperature reaches 36 DEG C, then multifunctional fluidized bed to start whitewashing, spouting velocity is set to 17rpm, is atomized Pressure is 1.70bar, because material is aggravated after whitewashing, temperature reduction, and air quantity is adjusted at any time and keeps material fully to jump, and at any time Regulation EAT makes temperature of charge close whitewashing after being maintained at 36 DEG C, whitewashing 20min, completes granulation;Again by multi-functional fluidisation The EAT of bed is set to 100 DEG C material is dried, and regulation air quantity keeps material fully to jump, when material moisture≤ When 2.0%, EAT is down to 25 DEG C, the temperature of material is reduced to 25 DEG C, finally discharging shutdown;
Step 6,
The particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then will The dry particl of selection, which is fitted into bag, completes filling.
Embodiment 2
A kind of preparation method of relieving cough and asthma Chinese medicine composition, including following operating procedure:
Step 1,
Weigh Momordica grosvenori 6kg, Exocarpium Citri Rubrum 6kg, Chinese torreyanut 5kg, sophora bud 7kg, purple perilla seed 7kg, balloonflower root 6kg, gingko 8kg, Chinese yam 8kg, lily 10kg, emblic 6kg, sterculia seed 7kg, almond 7kg, dried orange peel 5kg, cordate houttuynia 5kg, honeysuckle 3kg, Buddha's hand 4kg;
Step 2,
16 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts are decocted 2 hours, are added for the second time The water of 6 times of amounts, is decocted 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.20 (60 DEG C);
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby;
Step 4,
Weigh thick paste 24kg, maltodextrin 75.97kg and potassium sorbate 30g;Thick paste and water are uniformly mixing to obtain whitewashing, The weight ratio of thick paste and water is 1:2;
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 25m3/ h, EAT is set For 80 DEG C, heating premix is carried out to material 7 minutes, obtain mixed material;After premix is finished, by adjusting air quantity and entering wind-warm syndrome Degree so that mixed material temperature reaches 40 DEG C, then multifunctional fluidized bed to start whitewashing, spouting velocity is set to 15rpm, is atomized Pressure is 1.50bar, because material is aggravated after whitewashing, temperature reduction, and air quantity is adjusted at any time and keeps material fully to jump, and at any time Regulation EAT makes temperature of charge close whitewashing after being maintained at 40 DEG C, whitewashing 15min, completes granulation;Again by multi-functional fluidisation The EAT of bed is set to 100 DEG C material is dried, and regulation air quantity keeps material fully to jump, when material moisture≤ When 2.0%, EAT is down to 35 DEG C, the temperature of material is reduced to 35 DEG C, finally discharging shutdown;
Step 6,
The particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then will The dry particl of selection, which is fitted into bag, completes filling.
Embodiment 3
A kind of preparation method of relieving cough and asthma Chinese medicine composition, including following operating procedure:
Step 1,
Weigh Momordica grosvenori 6kg, Exocarpium Citri Rubrum 5kg, Chinese torreyanut 7kg, sophora bud 5kg, purple perilla seed 5kg, balloonflower root 5kg, gingko 9kg, Chinese yam 10kg, lily 9kg, emblic 6kg, sterculia seed 5kg, almond 8kg, dried orange peel 6kg, cordate houttuynia 5kg, honeysuckle 4kg, Buddha's hand 5kg;
Step 2,
16 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts are decocted 2 hours, are added for the second time The water of 6 times of amounts, is decocted 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.30 (60 DEG C);
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby;
Step 4,
Weigh thick paste 26.97kg, maltodextrin 73kg and potassium sorbate 30g;Thick paste and water are uniformly mixing to obtain whitewashing, The weight ratio of thick paste and water is 1:2;
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 15m3/ h, EAT is set For 100 DEG C, heating premix is carried out to material 12 minutes, obtain mixed material;After premix is finished, by adjusting air quantity and entering wind-warm syndrome Degree so that when mixed material temperature reaches 38 DEG C, then multifunctional fluidized bed to start whitewashing, spouting velocity is set to 18rpm, mist Change pressure is 2.0bar, because material is aggravated after whitewashing, temperature reduction, and air quantity is adjusted at any time and keeps material fully to jump, and with When regulation EAT temperature of charge is maintained at 38 DEG C, close whitewashing after whitewashing 30min, complete granulation;Again by multi-functional stream The EAT of change bed is set to 100 DEG C and material is dried, and regulation air quantity keeps material fully to jump, when the moisture of material When≤2.0%, EAT is down to 30 DEG C, the temperature of material is reduced to 30 DEG C, finally discharging shutdown;
Step 6,
The particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then will The dry particl of selection, which is fitted into bag, completes filling.
Embodiment 4
A kind of preparation method of relieving cough and asthma Chinese medicine composition, including following operating procedure:
Step 1,
Weigh Momordica grosvenori 7kg, Exocarpium Citri Rubrum 5kg, Chinese torreyanut 5kg, sophora bud 6kg, purple perilla seed 6kg, balloonflower root 6kg, gingko 7kg, Chinese yam 9kg, lily 9kg, emblic 7kg, sterculia seed 6kg, almond 7kg, dried orange peel 4kg, cordate houttuynia 7kg, honeysuckle 5kg, Buddha's hand 4kg;
Step 2,
16 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts are decocted 2 hours, are added for the second time The water of 6 times of amounts, is decocted 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.40 (60 DEG C);
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby;
Step 4,
Weigh thick paste 24.02kg, maltodextrin 75.97kg and potassium sorbate 10g;Thick paste and water are uniformly mixing to obtain spray The weight ratio of slurry, thick paste and water is 1:2;
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 20m3/ h, EAT is set For 95 DEG C, heating premix is carried out to material 15 minutes, obtain mixed material;After premix is finished, by adjusting air quantity and entering wind-warm syndrome Degree so that mixed material temperature reaches 35 DEG C, then multifunctional fluidized bed to start whitewashing, spouting velocity is set to 20rpm, is atomized Pressure is 1.70bar, because material is aggravated after whitewashing, temperature reduction, and air quantity is adjusted at any time and keeps material fully to jump, and at any time Regulation EAT makes temperature of charge close whitewashing after being maintained at 35 DEG C, whitewashing 25min, completes granulation;Again by multi-functional fluidisation The EAT of bed is set to 100 DEG C material is dried, and regulation air quantity keeps material fully to jump, when material moisture≤ When 2.0%, EAT is down to 45 DEG C, the temperature of material is reduced to 45 DEG C, finally discharging shutdown;
Step 6,
The particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then will The dry particl of selection, which is fitted into bag, completes filling.
Clinical data:
1st, case selection:
In order to verify the effect of Chinese medicine composition of the present invention, in December, -2015 in June, 2014, the patient 120 made a definite diagnosis is selected Example carries out clinical observation, wherein male 57, women 63, age 25-65 Sui, average age 42 years old, the course of disease -8 years 2 years.
Make a definite diagnosis standard:Without diseases caused by external factors symptom with cough throughout the year for cardinal symptom, or it is uncomfortable in chest with asthma, gurgling with sputum, shortness of breath, Auscultation of lung has different degrees of wheezing sound;Annual morbidity more than 2 months, and continuous more than 2 years.If patient's cough and asthma Elder generation Fa Qibiao is answered with diseases caused by external factors symptoms such as headache, heating, aversion to cold simultaneously, after after the disappearance of diseases caused by external factors symptom, if also there is cough and asthma symptom, It is then controlled with Chinese medicine composition of the present invention.
Exclude the tool such as pulmonary tuberculosis, pneumoconiosis, pulmonary abscess, bronchiectasis, heart disease, cardiac insufficiency, chronic naso-pharynageal disease Have cough, cough up phlegm, the other diseases of wheezing symptoms.
2nd, medicament selection:
Patient takes medicine of the present invention, and 2 times a day, each 10g, warm water delivery service in half an hour after meal, is within 30 days a treatment Journey, continuously takes 2 to 4 courses for the treatment of, and serious patient increases the amount of discretion.
3rd, efficacy determination:(issued with reference to State Administration of Traditional Chinese Medicine in 1994《Tcm internal medicine Illnesses Diagnoses curative effect mark It is accurate》)
(1) cure:Cough, cough and asthma symptom and lung's wheezing sound are wholly absent;
(2) it is effective:Cough, phlegm, breathe heavily symptom and be obviously improved, activity is without breaking-out;
(3) effectively:Cough, phlegm, breathe heavily symptom and substantially mitigate, attack times are reduced;
(4) it is invalid:Symptom does not improve or exacerbation of symptoms.
4th, result:
Take after drug therapy of the present invention, healing 64, effective 30, effective 16, invalid 10, cure rate is 53.3%, total effective rate 91.6%.In follow-up after half a year, 110 patients of effective therapeutic effect, recurrence rate is 22%.
Case 1
Lee of Shaanxi Province Shangluo City, female, 50 years old, cough is simultaneous to breathe heavily disease 4 years, and antibiotic, aminophylline and spraying is used for a long time Treatment, all diseases have alleviated after treatment;Come here it is medical when, cough is aggravated more than 20 days, and night is coughed very, tells thin frothy sputum, when Heat when cold, dry is bitter, uncomfortable in chest, thin white fur of tongue, shortness of breath and fatigue, veins string;Physical examination:Double lungs are covered with wheezing sound;Rabat is pointed out:Lung line Manage thickening, heart diaphragm no abnormality seen.Tcm diagnosis:Asthenic cold type bronchial astehma.Chinese medicine takes Chinese medicine of the present invention, daily two dose (one Agent 10g), after 2 courses for the treatment of, symptom is clearly better, and continues to take 1 course for the treatment of, cough and asthma symptom disappears substantially, and after treatment 1 The course for the treatment of.
Case 2
The Zheng of Shaanxi Province's Ankang City, female, before 58 years old, 2 years, patient is because of the disease for heating occur after flu, coughing and spitting Shape, by treating resolution of fever, coughs, spits incessantly, though the medicine such as Brown Mixtura, spiramvcin by oral administration, the state of an illness is still Prolong the several months.Second Year is often aggravated or induced because suffering from cold, and repeated coughing, is panted, is spat, nearly 4 months of the course of disease, often in night or icepro Morning coughs, usually repeated cold, when clear nasal discharge, rhiocnesmus eye itches, to the cold or strenuous exercise's cough is aggravated.Symptoms include:Cough frequency is made, shape Cold body is cold, it is more to tell yellow amount of expectoration, and asthma, cold extremities with aversion to cold is indigestion and loss of appetite, defecate partially dry, red tongue body, yellow tongue fur, superficial and rapid pulse.Auscultation:Double lungs are exhaled Sound-absorbing is thick, and audible and rhonchus is dispersed in when deep air-breathing and cough.Chest X ray is shown:Thorax is symmetrical, and tracheae is placed in the middle, and double lung marking increase It is many, obscure, marched off into political wilderness and attached most importance to right lung, heart diaphragm no abnormality seen.Tcm diagnosis:Asthenia in origin and asthenia in superficiality type cough and asthma is demonstrate,proved;Chinese medicine of the present invention is taken, After daily two doses (one 10g), 2 courses for the treatment of, symptom is clearly better, and coughs, spits, panting substantially mitigates;Continue to take 2 treatments Journey, cough, wheezing symptoms disappear, and double pulmonary respiration sounds are slightly thick, without dry moist rale.
Case 3
The Zhang of Shaanxi Province Weinan City Fuping County, 62 years old, man, cough was panted recurrent exerbation 2 years, before two weeks, because of weather Mutation causes cough and asthma to aggravate, and the thin amount of uttering phlegm is more, and shortness of breath receives difference, half congealed during stool, red tongue with thin and yellowish fur, stringy,thready and rapid pulse;Differential diagnosis in tcm Lung, deficiency of qi and fluid are lied prostrate for phlegm and retained fluid;Take daily two doses (one 10g) after this formula, after 1 course for the treatment of, cough and asthma is substantially taken a favourable turn, and is spat Amount is reduced, and continues to take 2 courses for the treatment of, cough and asthma disappears, and remaining symptom disappears.
Case 4
Shaanxi Province Yanan City week certain, 64 years old, female, asthma recurrent exerbation 2 years aggravated first quarter moon, because of weather before first quarter moon Quenching, old complaint breaking-out, sits up straight and crouches, municipal hospital is moved in then all day, is relievingd asthma through spasmolysis, anti-infective, pulmicort repules are sprayed Suction, SOA control, at nightfall can prostration, only morning, which still breathes heavily, has compeled seat, and wheezing sound in the throat coughs up phlegm not well, partially dry, the tongue of stool The thin yellow greasy of purple, wiry and frequent pulse.Dialectical to hand over resistance for mental disorder, lung closes mistake exhibition, and stagnation of phlegm converting into heat becomes.Take Chinese medicine of the present invention, daily two After agent (one 10g), 2 courses for the treatment of, cough and asthma mitigates, but morning has still needed to sit, and phlegm is also easily coughed up;Continue to take 2 courses for the treatment of, nothing is coughed Breathe heavily, nighttime sleep is quiet, recovery from illness.
Case 5
Shaanxi Province Yulin City Zhang, 45 years old, man, cough and asthma 2 months repeatedly, examine see it is uncomfortable in chest, cough, pant, night is very, coughs Phlegm color is sticky in vain, is difficult to bring up, and the micro- Huang of tongue fur is thin greasy, and matter is red, floating-rolling pulse number.It is dialectical to compel lung, impairment of dispersing and descending function of the lung for drink heat.Give and take Use after Chinese medicine of the present invention, daily two doses (one 10g), 2 courses for the treatment of, further consultation cough and asthma is clearly better, and coughs up phlegm still malaise;Continue 1 course for the treatment of of medicine of the present invention is taken, cough substantially mitigates, and asthma has been put down, only morning still cough and asthma, and the amount of coughing up phlegm is few, and thin lingual fur is yellow, Greasy tongue has moved back, and matter is red, slippery;Continue to take 1 course for the treatment of of medicine of the present invention, no cough and asthma, nighttime sleep is quiet, recovery from illness.

Claims (4)

1. a kind of relieving cough and asthma Chinese medicine composition, it is characterised in that by mass percentage, raw materials used by following components group Into:
Momordica grosvenori 5%~7%, Exocarpium Citri Rubrum 5%~7%, Chinese torreyanut 5%~7%, the sophora bud 5%~7%, purple perilla seed 5%~7%, balloonflower root 5%~7%, gingko 7%~9%, Chinese yam 8%~10%, lily 8%~10%, emblic 5%~7%, the sterculia seed 5%~ 7%th, almond 7%~9%, dried orange peel 4%~6%, cordate houttuynia 5%~7%, honeysuckle 3%~5%, Buddha's hand 4%~6%, the above The mass percent summation of each component is 100%.
2. the preparation method of relieving cough and asthma Chinese medicine composition described in a kind of claim 1, it is characterised in that including following operation step Suddenly:
Step 1,
By mass percentage, Momordica grosvenori 5%~7%, Exocarpium Citri Rubrum 5%~7%, Chinese torreyanut 5%~7%, the sophora bud 5%~7%, purple are weighed Perillaseed 5%~7%, balloonflower root 5%~7%, gingko 7%~9%, Chinese yam 8%~10%, lily 8%~10%, emblic 5% ~7%, the sterculia seed 5%~7%, almond 7%~9%, dried orange peel 4%~6%, cordate houttuynia 5%~7%, honeysuckle 3%~5%, Buddha's hand 4%~6%, the mass percent summation of above each component is 100%;
Step 2,
16 taste raw materials in step 1 are added water to cook twice, the water of 10 times of amounts are added for the first time, are decocted 2 hours, second plus 6 times The water of amount, is decocted 2 hours, merges decocting liquid twice, filtering, it is the thick of 1.20~1.40 (60 DEG C) that filtrate, which is concentrated into relative density, Cream;
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby;
Step 4,
By mass percentage, thick paste 24%~26.97%, maltodextrin 73%~75.97% and sorb that step 1 is obtained are weighed Sour potassium 0.01%~0.03%, the mass percent summation of above each component is 100%;Thick paste and water are uniformly mixing to obtain spray The weight ratio of slurry, thick paste and water is 1:2;
Step 5,
In multifunctional fluidized bed, maltodextrin and potassium sorbate are subjected to material heating and premixed, mixed material is obtained, it is then past Whitewashing is pelletized on mixed material, is finally dried, cools, discharges, is shut down;
Step 6,
Last whole grain and filling, is produced.
3. the preparation method of relieving cough and asthma Chinese medicine composition according to claim 2, it is characterised in that:, will in the step 5 Maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 15m3/ h~25m3/ h, EAT is set to 80 DEG C~100 DEG C, heating premix is carried out to material 7~15 minutes, obtain mixed material;Premix finish after, by adjust air quantity and EAT so that mixed material temperature reaches 35 DEG C~40 DEG C, then multifunctional fluidized bed to start whitewashing, spouting velocity is set For 15rpm~20rpm, atomizing pressure is 1.50bar~2.0bar, because material is aggravated after whitewashing, and temperature reduction is adjusted at any time Air quantity keeps material fully to jump, and regulation EAT makes temperature of charge be maintained at 35 DEG C~40 DEG C at any time, and the 15min that whitewashes~ Whitewashing is closed after 30min, granulation is completed;Multifunctional fluidized bed EAT is set into 100 DEG C again material is dried, Regulation air quantity keeps material fully to jump, and when the moisture≤2.0% of material, EAT is down into 25 DEG C~45 DEG C, makes thing The temperature of material is reduced to 25 DEG C~45 DEG C, finally discharging shutdown.
4. the preparation method of relieving cough and asthma Chinese medicine composition according to claim 2, it is characterised in that:, will in the step 6 The particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then by dry of selection Grain, which is fitted into bag, completes filling.
CN201710219567.1A 2017-04-06 2017-04-06 A kind of relieving cough and asthma Chinese medicine composition and preparation method Pending CN107029099A (en)

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