CN107001436B - 用于治疗肌纤蛋白(myoc)青光眼的腺伴随病毒载体 - Google Patents

用于治疗肌纤蛋白(myoc)青光眼的腺伴随病毒载体 Download PDF

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CN107001436B
CN107001436B CN201580061882.5A CN201580061882A CN107001436B CN 107001436 B CN107001436 B CN 107001436B CN 201580061882 A CN201580061882 A CN 201580061882A CN 107001436 B CN107001436 B CN 107001436B
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myoc
aav
rspo3
capsid
mammal
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CN107001436A (zh
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P·佩汉
A·斯卡利亚
J·阿丁格
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Genzyme Corp
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Genzyme Corp
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CN201580061882.5A 2014-09-16 2015-09-16 用于治疗肌纤蛋白(myoc)青光眼的腺伴随病毒载体 Active CN107001436B (zh)

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CN202211533202.3A CN116585492A (zh) 2014-09-16 2015-09-16 用于治疗肌纤蛋白(myoc)青光眼的腺伴随病毒载体

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US201462051299P 2014-09-16 2014-09-16
US62/051,299 2014-09-16
PCT/US2015/050515 WO2016044478A1 (en) 2014-09-16 2015-09-16 Adeno-associated viral vectors for treating myocilin (myoc) glaucoma

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CN107001436B true CN107001436B (zh) 2023-01-06

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CN202211533202.3A Pending CN116585492A (zh) 2014-09-16 2015-09-16 用于治疗肌纤蛋白(myoc)青光眼的腺伴随病毒载体

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US (1) US10821193B2 (enExample)
EP (1) EP3194601B1 (enExample)
JP (2) JP6673923B2 (enExample)
KR (2) KR102612871B1 (enExample)
CN (2) CN107001436B (enExample)
AU (2) AU2015317756B2 (enExample)
BR (1) BR112017005235B1 (enExample)
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KR102612871B1 (ko) 2014-09-16 2023-12-13 젠자임 코포레이션 마이오실린(myoc) 녹내장을 치료하기 위한 아데노-관련 바이러스 벡터
US11845952B2 (en) * 2018-02-07 2023-12-19 Nippon Medical School Foundation Adeno-associated virus vector
US20210030719A1 (en) * 2018-02-22 2021-02-04 University Of South Florida Grp94 inhibitors to treat steroid-induced ocular hypertensions and glaucomas
JP2022522756A (ja) 2019-02-28 2022-04-20 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 治療薬の送達のためのアデノ随伴ウイルスベクター
WO2022120080A1 (en) * 2020-12-03 2022-06-09 University Of Massachusetts Development of novel gene therapeutics for fibrodysplasia ossificans progressiva
CN113032010B (zh) * 2021-03-12 2022-09-20 歌尔科技有限公司 命令的传输控制方法、终端及计算机可读存储介质
US20240318175A1 (en) * 2021-06-28 2024-09-26 Alnylam Pharmaceuticals, Inc. Compositions and Methods for Silencing MYOC Expression
US20250087355A1 (en) * 2021-12-16 2025-03-13 Peter Koulen A machine learning based framework using electroretinography for detecting early stage glaucoma
CN117343152B (zh) * 2023-04-18 2024-06-04 上海本导基因技术有限公司 一种用于治疗青光眼疾病的慢病毒样颗粒
CN118546217B (zh) * 2024-07-25 2024-10-29 广州译码基因科技有限公司 靶向小梁网、角膜缘及rpe的aav衣壳蛋白及其应用

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