CN106890818A - Microcarrier cleaning equipment - Google Patents
Microcarrier cleaning equipment Download PDFInfo
- Publication number
- CN106890818A CN106890818A CN201510956325.1A CN201510956325A CN106890818A CN 106890818 A CN106890818 A CN 106890818A CN 201510956325 A CN201510956325 A CN 201510956325A CN 106890818 A CN106890818 A CN 106890818A
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- CN
- China
- Prior art keywords
- microcarrier
- cleaning
- reaction
- plate rail
- reaction plate
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
- B08B3/10—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
- B08B3/102—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration with means for agitating the liquid
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- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention discloses a kind of microcarrier cleaning equipment, including platter, reaction plate rail, microcarrier adsorbent equipment and cleaning device, platter is provided with the upward reaction cup of spaced multiple rims of a cup, reaction plate rail is provided with the mounting hole for placing platter, microcarrier adsorbent equipment is arranged on the lower section of reaction plate rail, microcarrier adsorbent equipment includes substrate and the multiple magnets being arranged on substrate, multiple magnets are correspondingly arranged with multiple reaction cups respectively, and cleaning device is arranged on the top of reaction plate rail.Platter is arranged on the mounting hole of reaction plate rail, cleaning device above reaction plate rail can carry out cleaning operation to reaction cup, due to reaction cup need not be arranged on rotary rotation disk again, thus effectively prevent the cross pollution caused when reaction cup rotates.Microcarrier adsorbent equipment is arranged on the lower section of reaction plate rail, and microcarrier can be by magnet absorption in the bottom of reaction cup in cleaning, and more preferably, microcarrier is not easy loss to absorption affinity, cleans more abundant.
Description
Technical field
The present invention relates to medical instruments field, more particularly to a kind of microcarrier cleaning equipment.
Background technology
Chemiluminescence immunoassay technology is short due to the reaction time, simple to operate, thus greatly increases and exempt from
The operating efficiency of epidemic disease diagnosis, is widely used in medical treatment and scientific research field.Chemical illumination immunity analysis instrument is to use
In the instrument of measurement humoral chemistry composition, it is widely used in situation of all-level hospitals, epidemic prevention station at present.
Using microcarrier as reaction carriers, a corpse or other object for laboratory examination and chemical testing only needs a small amount of sample i.e. to chemical illumination immunity analysis instrument
Multinomial detection can be simultaneously carried out, clinical more accurate, easy, quick and tool cost advantage disease sieve can be provided
Inspection and diagnostic service.Chemiluminescence immunoassay point instrument at present on the market is usually provided with multiple reaction cups as anti-
Container is answered, after body fluid sample to be analyzed is added in reaction cup, then contains absorption to being added in reaction cup
There are the micron or the reaction reagent of nano level microcarrier of antigen or antibody.After the completion of sample and reagent reacting,
Reaction cup is moved to cleaning needle lower section by rotating disk, dress is adsorbed using the microcarrier rotated on the inside of disk
Absorption microcarrier is put, cleaning needle carries out injection cleaning fluid and suctions out waste liquid operation afterwards, and such repetitiousness is completing
Cleaning process.
But prior art is present in problems with needs improvement:
1) it is rotary rotate set on disk it is multiple close to reaction cup, smoothness is not good when rotated easily makes
Into cross pollution；
2) microcarrier is largely adsorbed in side, absorption affinity deficiency microcarrier in cleaning by microcarrier adsorbent equipment
Easily loss, cleans also not abundant enough.
The content of the invention
Based on this, the invention reside in the defect for overcoming prior art, there is provided a kind of microcarrier cleaning equipment, no
It is only capable of reducing the possibility of cross pollution, and microcarrier loss late is low, cleans also cleaner.
Its technical scheme is as follows：
A kind of microcarrier cleaning equipment, including platter, reaction plate rail, microcarrier adsorbent equipment and cleaning dress
Put, the platter is provided with the upward reaction cup of spaced multiple rims of a cup, is set on the reaction plate rail
There is the mounting hole for placing the platter, the microcarrier adsorbent equipment is arranged on the lower section of reaction plate rail,
The microcarrier adsorbent equipment includes substrate and multiple magnets for being arranged on substrate, multiple magnets respectively with it is many
Individual reaction cup is correspondingly arranged, and the cleaning device is arranged on the top of reaction plate rail.
Wherein in one embodiment, the microcarrier cleaning equipment also includes the first drive mechanism, described the
One drive mechanism can drive microcarrier adsorbent equipment to be moved towards the direction closer or far from the reaction plate rail.
Wherein in one embodiment, the microcarrier cleaning equipment also includes the second drive mechanism, described clear
Cleaning device includes lifting seat, cleaning agent storage tank, waste tank and multiple cleaning needles, and the cleaning needle is arranged on
On the lifting seat, the cleaning agent storage tank, waste tank are connected by pipeline with cleaning needle respectively, and
Be provided with liquid pump and triple valve on the pipeline, second drive mechanism can drive lifting seat towards near or it is remote
From the direction movement of the reaction plate rail.
Wherein in one embodiment, the microcarrier cleaning equipment also includes oscillating plate and eccentric motor, institute
State oscillating plate to be connected with the reaction plate rail by the first spring, the output shaft of the eccentric motor is provided with partially
Heart block, the eccentric block is provided with the first protruding shaft, and the oscillating plate is provided with the second protruding shaft, and described first is convex
Second spring is connected between axle and the second protruding shaft.
Wherein in one embodiment, first spring is four, and four first springs are connected respectively
Between reaction plate rail and four corners of oscillating plate, first protruding shaft is one, and second protruding shaft is
Two, two the second protruding shaft interval settings simultaneously by corresponding second spring are connected to described first respectively
In protruding shaft, the transitional pore matched with the substrate is additionally provided with the oscillating plate.
Wherein in one embodiment, the magnet is inlaid on substrate, and the magnet is around the reaction
Cup is set.
Wherein in one embodiment, the microcarrier cleaning equipment also includes control device, and described first drives
Motivation structure and cleaning device are electrically connected with control device respectively, when the cleaning device starts, control dress
Putting the first drive mechanism of control makes microcarrier adsorbent equipment be moved towards near the direction of the reaction plate rail；Institute
When stating cleaning device stopping, the first drive mechanism of control device control makes microcarrier adsorbent equipment towards away from described
React the direction movement of plate rail.
Wherein in one embodiment, the platter is disposable porous plate.
Wherein in one embodiment, the microcarrier cleaning equipment also includes test casing, the test box
Accommodating chamber is provided with vivo, the reaction plate rail, microcarrier adsorbent equipment and cleaning device are arranged at accommodating chamber
In, it is additionally provided with switchable hermatic door on the test casing.
Wherein in one embodiment, the control device includes being used to provide being needed in the specified platter of user
The cleaning selecting module of the reaction cup to be cleaned.
The advantage or principle to preceding solution are illustrated below：
Above-mentioned microcarrier cleaning equipment, platter is arranged on the mounting hole of reaction plate rail, positioned at reaction plate rail
The cleaning device of top can carry out cleaning operation to the reaction cup in platter, due to without again setting reaction cup
Put and rotated on disk rotary, thus effectively prevent the cross pollution caused when reaction cup rotates.Micro- load
Body adsorbent equipment is arranged on the lower section of reaction plate rail, and microcarrier can be by magnet absorption in reaction cup in cleaning
Bottom, more preferably, microcarrier is not easy loss to absorption affinity, cleans more abundant.
Brief description of the drawings
Fig. 1 is the structural representation of the platter described in the embodiment of the present invention；
Fig. 2 is the structural representation one of the microcarrier cleaning equipment described in the embodiment of the present invention；
Fig. 3 is the structural representation two of the microcarrier cleaning equipment described in the embodiment of the present invention；
Fig. 4 is the structural representation of the test casing described in the embodiment of the present invention.
Description of reference numerals：
1st, platter, 2, reaction plate rail, 3, microcarrier adsorbent equipment, 4, cleaning device, 5, first drives
Motivation structure, the 6, second drive mechanism, 7, oscillating plate, 8, eccentric motor, 9, test casing, 10, anti-
Answer cup, 20, mounting hole, 40, lifting seat, 41, cleaning needle, the 70, first spring, 72, second spring,
80th, eccentric block, 90, hermatic door.
Specific embodiment
Embodiments of the invention are described in detail below：
As shown in Figure 1, 2, 3, the microcarrier cleaning equipment described in the present embodiment, including platter 1, reaction
Plate rail 2, microcarrier adsorbent equipment 3 and cleaning device 4, the platter 1 are provided with spaced multiple
The upward reaction cup 10 of rim of a cup, the reaction plate rail 2 is provided with the mounting hole for placing the platter 1
20, the microcarrier adsorbent equipment 3 is arranged on the lower section of reaction plate rail 2, the microcarrier adsorbent equipment 3
Including substrate and the multiple magnets being arranged on substrate, multiple magnets are correspondingly arranged with multiple reaction cups 10 respectively,
The cleaning device 4 is arranged on the top of reaction plate rail 2.Above-mentioned microcarrier cleaning equipment, platter 1 is pacified
On the mounting hole 20 of reaction plate rail 2, the cleaning device 4 positioned at the top of reaction plate rail 2 can be to platter
Reaction cup 10 on 1 carries out cleaning operation, due to without reaction cup 10 is arranged on into rotary rotation disk again
On, thus effectively prevent the cross pollution caused when reaction cup 10 rotates.Microcarrier adsorbent equipment 3 is set
In the lower section of reaction plate rail 2, microcarrier can be by magnet absorption in the bottom of reaction cup 10, absorption in cleaning
More preferably, microcarrier is not easy loss to power, cleans more abundant.
As shown in figure 1, the platter 1 that the present embodiment is used is disposable 96 orifice plate, 96 can be simultaneously carried out
The cleaning of individual sample, the stationarity of cleaning process rotates disk better than rotary, and substantial amounts of sample size can be saved
Save time and manpower, and single use can reduce pollution rate.Certainly, platter 1 can also be 24 orifice plates
Or 48 porous plates such as orifice plate, the type of platter 1 refuses to limit.
As shown in figure 3, the microcarrier cleaning equipment also includes the first drive mechanism 5, first driving machine
Structure 5 can drive microcarrier adsorbent equipment 3 to be moved towards the direction closer or far from the reaction plate rail 2.At this
In embodiment, the microcarrier cleaning equipment also includes control device, first drive mechanism 5 and cleaning
Device 4 is electrically connected with control device respectively, and when the cleaning device 4 starts, control device controls the
One drive mechanism 5 makes microcarrier adsorbent equipment 3 be moved towards near the direction of the reaction plate rail 2；Described
Cleaning device 4 stop when, control device control the first drive mechanism 5 make microcarrier adsorbent equipment 3 towards away from
The direction movement of the reaction plate rail 2.When microcarrier is cleaned, microcarrier adsorbent equipment 3 inhales microcarrier
It is attached on the inwall of reaction cup 10, reduces the loss of microcarrier.When microcarrier reacts, microcarrier absorption dress
3 are put away from platter 1, microcarrier can be suspended in the liquid of reaction cup 10, course of reaction does not receive magnetic field shadow
Ring.The present embodiment is from BLDC motors as the first drive mechanism 5.
As shown in Fig. 2 the magnet totally 59, is inlaid on substrate, the magnetic in mode arranged in a crossed manner
Body is set around the reaction cup 10, microcarrier can be strengthened into absorption on the inwall of reaction cup 10, reduces
The loss of microcarrier.The microcarrier cleaning equipment also includes the second drive mechanism 6, and the cleaning device 4 is wrapped
Lifting seat 40, cleaning agent storage tank, waste tank and eight cleaning needles 41 are included, eight cleaning needles 41 set side by side
Put on the lifting seat 40, the cleaning agent storage tank, waste tank pass through pipeline and cleaning needle 41 respectively
Connection, and liquid pump and triple valve are provided with the pipeline, second drive mechanism 6 can drive lifting
Seat 40 realizes imbibition or fluid injection operation towards the direction movement closer or far from the reaction plate rail 2.
In the present embodiment, the microcarrier cleaning equipment also includes oscillating plate 7 and eccentric motor 8, described to shake
Dynamic plate 7 is connected by the first spring 70 with the reaction plate rail 2, is set on the output shaft of the eccentric motor 8
There is eccentric block 80, the eccentric block 80 is provided with the first protruding shaft, and the oscillating plate 7 is provided with the second protruding shaft,
Second spring 72 is connected between first protruding shaft and the second protruding shaft.Wherein, first spring 70 is four
Individual, four first springs 70 are connected between reaction plate rail 2 and four corners of oscillating plate 7,
First protruding shaft is one, and second protruding shaft is two, and two the second protruding shaft interval settings are simultaneously divided
It is not connected in first protruding shaft by corresponding second spring 72, is additionally provided with the oscillating plate 7 and institute
The transitional pore of substrate matching is stated, substrate is passed through from transitional pore.Eccentric motor 8 drive oscillating plate 7 from
And cause that the platter 1 on reaction plate rail 2 completes vibration in the way of " 8 " font, fully shakes up reaction cup
Material in 10.The present embodiment is from stepper motor as eccentric motor 8.
As shown in figure 4, the microcarrier cleaning equipment also includes test casing 9, set in the test casing 9
There is accommodating chamber, the reaction plate rail 2, microcarrier adsorbent equipment 3 and cleaning device 4 are arranged in accommodating chamber,
Play a protective role, switchable hermatic door 90 is additionally provided with the test casing 9, it is convenient to install and change
Platter 1.
Microcarrier cleaning equipment described in the present embodiment has a set of software coordinated with control device, can be right
Microcarrier cleaning parameter and process be controlled, including the differential responses stage microcarrier cleaning selection, it is micro-
Carrier breaks up, react plate rail 2 cleans, pipeline-cleaning and service mode etc..Control device is received and comes from software
Operational order and according to operational order to the first drive mechanism 5, the second drive mechanism 6, eccentric motor 8,
Liquid pump and triple valve are controlled, and complete whole cleaning process.Test casing 9 is provided with touch LCD and shows
Show device, may be selected to need the position of cleaning and show real-time status, convenient operation.
Touch LCD display has the patterning interface for being supplied to user to operate, and can carry out following operation：
1、Menu Bar:Row of Well, Auto Rinsing Time, Touch Calibration may be selected,
Data/Time and IP Address set.
2、Virtual Keyboard:Numeric type dummy keyboard is provided.
3、Procedure Selection:BMB, BMB Disperse, ELISA, CUSTOM, RINSE are provided,
RUN, STOP are selected.
4、Screen Saver:Screen protection program.
5、Message Box:Display information is used, such as operation information, error message etc..
6、Row of Well Selection:Cleaning selecting module, can directly click the reaction for wanting cleaning
Cup 10.
Each technical characteristic of embodiment described above can be combined arbitrarily, not right to make description succinct
The all possible combination of each technical characteristic in above-described embodiment is all described, as long as however, these skills
The combination of art feature does not exist contradiction, is all considered to be the scope of this specification record.
Embodiment described above only expresses several embodiments of the invention, and its description is more specific and detailed,
But can not therefore be construed as limiting the scope of the patent.It should be pointed out that for this area
For those of ordinary skill, without departing from the inventive concept of the premise, some deformations can also be made and changed
Enter, these belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be with appended power
Profit requires to be defined.
Claims (10)
1. a kind of microcarrier cleaning equipment, it is characterised in that inhaled including platter, reaction plate rail, microcarrier
Adsorption device and cleaning device, the platter are provided with the upward reaction cup of spaced multiple rims of a cup, institute
State reaction plate rail and be provided with mounting hole for placing the platter, the microcarrier adsorbent equipment is arranged on
The lower section of plate rail is reacted, the microcarrier adsorbent equipment includes substrate and the multiple magnets being arranged on substrate,
Multiple magnets are correspondingly arranged with multiple reaction cups respectively, and the cleaning device is arranged on the top of reaction plate rail.
2. microcarrier cleaning equipment according to claim 1, it is characterised in that also driven including first
Mechanism, first drive mechanism can drive microcarrier adsorbent equipment towards closer or far from the reaction plate rail
Move in direction.
3. microcarrier cleaning equipment according to claim 2, it is characterised in that also driven including second
Mechanism, the cleaning device includes lifting seat, cleaning agent storage tank, waste tank and multiple cleaning needles, described
Cleaning needle is arranged on the lifting seat, and the cleaning agent storage tank, waste tank are respectively by pipeline and cleaning
Pin is connected, and liquid pump and triple valve are provided with the pipeline, and second drive mechanism can drive lifting
Seat is moved towards the direction closer or far from the reaction plate rail.
4. microcarrier cleaning equipment according to claim 3, it is characterised in that also including oscillating plate and
Eccentric motor, the oscillating plate by the first spring with it is described reaction plate rail be connected, the eccentric motor it is defeated
Shaft is provided with eccentric block, and the eccentric block is provided with the first protruding shaft, and the oscillating plate is provided with the second protruding shaft,
Second spring is connected between first protruding shaft and the second protruding shaft.
5. microcarrier cleaning equipment according to claim 4, it is characterised in that first spring is
Four, four first springs are connected between reaction plate rail and four corners of oscillating plate, described
First protruding shaft is one, and second protruding shaft is two, and two the second protruding shaft interval settings are simultaneously led to respectively
Cross corresponding second spring to be connected in first protruding shaft, be additionally provided with the oscillating plate and the substrate
The transitional pore matched somebody with somebody.
6. microcarrier cleaning equipment according to claim 5, it is characterised in that the magnet is inlaid in
On substrate, and the magnet is set around the reaction cup.
7. the microcarrier cleaning equipment according to claim any one of 4-6, it is characterised in that also include
Control device, first drive mechanism and cleaning device are electrically connected with control device respectively, described clear
When cleaning device starts, the first drive mechanism of control device control makes microcarrier adsorbent equipment towards near the reaction
The direction movement of plate rail；When the cleaning device stops, the first drive mechanism of control device control makes micro- load
Body adsorbent equipment is moved towards the direction away from the reaction plate rail.
8. microcarrier cleaning equipment according to claim 7, it is characterised in that the platter is
Secondary property porous plate.
9. microcarrier cleaning equipment according to claim 7, it is characterised in that also including test casing,
Accommodating chamber is provided with the test box body, the reaction plate rail, microcarrier adsorbent equipment and cleaning device are all provided with
Put in accommodating chamber, switchable hermatic door is additionally provided with the test casing.
10. microcarrier cleaning equipment according to claim 7, it is characterised in that the control device
Cleaning selecting module including specifying the reaction cup that cleaning is needed in platter for providing user.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510956325.1A CN106890818A (en) | 2015-12-17 | 2015-12-17 | Microcarrier cleaning equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510956325.1A CN106890818A (en) | 2015-12-17 | 2015-12-17 | Microcarrier cleaning equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106890818A true CN106890818A (en) | 2017-06-27 |
Family
ID=59189447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510956325.1A Pending CN106890818A (en) | 2015-12-17 | 2015-12-17 | Microcarrier cleaning equipment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106890818A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109807106A (en) * | 2019-03-21 | 2019-05-28 | 安图实验仪器(郑州)有限公司 | Full automatic support disc type slide shakes wiper mechanism |
| CN111215382A (en) * | 2019-10-17 | 2020-06-02 | 海宁华悦电子有限公司 | High-efficient belt cleaning device of ferrite |
-
2015
- 2015-12-17 CN CN201510956325.1A patent/CN106890818A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109807106A (en) * | 2019-03-21 | 2019-05-28 | 安图实验仪器(郑州)有限公司 | Full automatic support disc type slide shakes wiper mechanism |
| CN111215382A (en) * | 2019-10-17 | 2020-06-02 | 海宁华悦电子有限公司 | High-efficient belt cleaning device of ferrite |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170627 |
|
| WD01 | Invention patent application deemed withdrawn after publication |