CN207232181U - A kind of rotating disc type Electrogenerated chemiluminescent immunoassay instrument - Google Patents
A kind of rotating disc type Electrogenerated chemiluminescent immunoassay instrument Download PDFInfo
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- CN207232181U CN207232181U CN201721163979.XU CN201721163979U CN207232181U CN 207232181 U CN207232181 U CN 207232181U CN 201721163979 U CN201721163979 U CN 201721163979U CN 207232181 U CN207232181 U CN 207232181U
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Abstract
The utility model discloses a kind of rotating disc type Electrogenerated chemiluminescent immunoassay instrument, it includes electrochemical luminescence test cell (105), can be driven in rotation the rotating turntable (100) of device (108) driving and an at least sampling probe (107), one in wherein described sampling probe (107) is in fluid communication with the electrochemical luminescence test cell (105), wherein the turntable (100) is equipped with along at least two in its circumferentially distributed following four reagent position in storehouse：Detection reagent position in storehouse (101), system reagent position in storehouse (102), sample to be tested position in storehouse (103) and incubation cup position in storehouse (104).Rotating disc type Electrogenerated chemiluminescent immunoassay instrument in the utility model is while the automation function of instrument is retained, greatly reduce moving component, the robustness of apparatus structure and the reliability of analysis result are improved, less but equipment instrument occasion as compact as possible is required suitable for test sample amount.
Description
Technical field
The utility model belongs to Electrogenerated chemiluminescent immunoassay instrument field, and in particular to a kind of rotating disc type electrochemical luminescence
Immunity analysis instrument.
Background technology
It is widely used in electrochemical luminescence (ECL) the technology generally use tris (bipyridine) ruthenium [Ru (bpy) of clinical immunoassays3
]2+Succinimide ester (i.e. NHS esters) be used as label, antibody or antigen are marked.Being formed, antibody/antigen is compound
After body, by electrochemical reaction and a series of subsequent chemical reaction in electrochemistry flow cell, luminous excitation is ultimately resulted in
The formation of state, produces detectable luminous signal.Mark molecule tris (bipyridine) ruthenium as generation detection signal is in coreagent
Tripropyl amine (TPA) (TPA, N (CH2CH2CH3)3) participate under electrochemical luminescence process it is as follows：
[Ru(bpy)3]2+-e-→[Ru(bpy)3]3+ (1)
N(CH2CH2CH3)3-e-→N(CH2CH2CH3)3 ·+ (2)
N(CH2CH2CH3)3 ·+-H+→(CH3CH2CH2)2NC·HCH2CH3 (3)
(CH3CH2CH2)2NC·HCH2CH3+[Ru(bpy)3]3+→[Ru(bpy)3]2+* (4)
[Ru(bpy)3]2+*→[Ru(bpy)3]2++hν (5)
Actual immunoassay according to the property (feature such as molecular size) of measured object also relate to antibody antigen how group
Close, with reference to order etc. examine project development details.Exemplified by commonly used in illustrating the sandwich method of immunoassay principle,
In ECL immunoassays, capture antibody is reacted by biotin and Streptavidin is fixed on magnetic particle surface, and signal antibody
Amido site is marked by tris (bipyridine) ruthenium.Two antibody and measured object form antibody-antigen-antibody sandwich on magnetic particle surface
After structural composites, a specific electrochemistry flow cell is brought into.Will in the sandwich structure complex that magnetic bead surfaces are formed
Electrochemical working electrode surface is fixed on by the magnet under flow cell.In the buffer solution system containing tripropyl amine (TPA), in spy
Determine under current potential (such as 1.4V vs.Ag/AgCl), tris (bipyridine) ruthenium [Ru (bpy)3]2+With coreagent tripropyl amine (TPA) in electrochemistry stream
The electrochemical oxidation reactions that working electrode (anode) surface experience in dynamic pond loses an electronics form the [Ru of trivalent respectively
(bpy)3]3+With radical cation N (CH2CH2CH3)3 ·+(reaction 1 and 2).The latter is very unstable, soon loses a proton
(H+) become a kind of Neutral radical (CH with strong reducing power3CH2CH2)2NC·HCH2CH3.[the Ru (bpy) of trivalent3]3+
Then by (CH3CH2CH2)2NC·HCH2CH3Reduction forms the divalence [Ru (bpy) of excitation state3]2+*.[Ru in excitation state
(bpy)3]2+*The photon of one wavelength 615nm of release returns to ground state [Ru (bpy)3]2+.This process electrode surface repeat into
OK, many photons are constantly produced, are enhanced optical signal.The optical signal that photodetector above flow cell detects
The measurer of measured object that is captured with magnetic bead surfaces of intensity have correlation, so as to carry out quantitative analysis to measured object.
In current clinical analysis practice, above process luminescence process and its advantage are in an electrification automated
Learn what is realized on luminescence immunoassay instrument.The instrument examines project for specific, is moved automatically according to program set in advance
(antibody or antigen of mark, biotinylated antibody or antigen and magnetic are micro- for the reagent for taking in Electrogenerated chemiluminescent immunoassay
Grain etc.) and analyzed sample, and be added into the container (being incubated cup or reaction cup) for immune response.Certain time
Afterwards, immune complex being formed in cup is incubated, being combined with magnetic bead is injected into an electrochemical luminous flowing pond again, in work
Make to apply a specific voltage between electrode and reference electrode, so that it may obtain electrochemical luminescence signals.After completing an analysis test,
Cleaned liquid band is gone out flow cell by magnetic bead and sandwich epidemic disease compound on electrode surface, and electrode surface is specific through one
After cleaning and regeneration and electrochemistry chemical state Balance Treatment process, the test available for next sample.
Above overall process is realized on Electrogenerated chemiluminescent immunoassay instrument and global function is related to plurality of liquid, liquid mixes
Compound or liquid/solid mixtures.They are divided into following four classes by property：
A, for the detection reagent of particular test project, include but is not limited to, biotinylated antibody or antigenic solution,
The antibody or antigenic solution of luminous marker (such as tris (bipyridine) ruthenium) mark, bead suspension, for the sample of high concentration sample
This dilution, for dissociation solution of some non-free measured objects etc.；
B, the system reagent unrelated with particular test project, including but not limited to, tripropyl amine (TPA) buffer solution, for flow cell
The alkali electrochemical cleaning solution of cleaning, for the oxidisability cleaning solution of instrument maintenance, the pure water for avoiding cross contamination cleans
Liquid；
C, tested sample, including but not limited to, serum, blood plasma, urine or other body fluid etc.；
D, by mixing and (reacting or dilute) mixture to be formed, including but not limited to, stage by stage by A classes and C classes
The immune complex that material adds container (being incubated cup or reaction cup) and formed, the low concentration that high concentration sample is formed after dilution
Sample, the sample to be tested that non-free measured object is formed after being dissociated etc..
In the instrument of all past different styles, this four class I liquid I, liquid mixture, liquid/solid mixing are stored
The container of thing and independently put for carrying out liquid phase and liquid/solid phase reaction or diluted container (being incubated cup or reaction cup)
Put in the different spatial of Electrogenerated chemiluminescent immunoassay instrument.The instrument knot designed for the storage and mixing of these liquid
Structure unit (or position in storehouse) has：
- detection reagent position in storehouse, it places A class detection reagents；
- system reagent position in storehouse, it places B class system reagents；
- sample to be tested position in storehouse, it places sample to be tested；
- cup position in storehouse is incubated, it, which is placed, is incubated cup, and equivalent to reactor, various reagents carry out anti-the incubation cup in the cup
Should；
- other cleaning solution positions in storehouse；
- other medical disposable material positions in storehouse.
Use turntable as position in storehouse come the position of transfer liquid container to facilitate sampling probe to be pipetted in the position of a certain fixation
The method of liquid is the usual method in chemical illumination immunity analysis instrument, Biochemical Analyzer and many other analytical instrument, and
And there is use on all Roche Electrogenerated chemiluminescent immunoassay instrument.Such as 1010 immunoassays of Elecsys in Roche
Incubating device on instrument is a rotary turnplate, and the Elecsys 2010 of Roche and cobas e 411 at the same time have reagent and
Two turntables of sample.Also have in addition to the position in storehouse or mechanism unit of various liquid and liquid/solid mixtures is placed, on instrument and move
Take liquid or the device of liquid/solid mixtures (comprising sampling probe and mechanical arm etc.), waste liquid collection vessel, (include three electrodes
Electrochemical luminous flowing pond, photomultiplier and magnetic capture mechanism) electrochemical luminescence measuring unit, (electrochemistry, fluid path,
Signal acquiring and processing etc.) control circuit, sample bar code read in, result output display etc. unit, module and subsystem.
But the rotating disc type Electrogenerated chemiluminescent immunoassay instrument of all prior arts have the characteristics that one it is common, it is as each
Class reagent position in storehouse is all separately provided a holding structure, otherwise it is rectangle fixed mechanism, otherwise it is turntable.In other words, exist
When using turntable, same type of reagent position in storehouse is provided only with each turntable, different classes of liquid position in storehouse is only
Stand up what is put, its locus is fixed relative to instrument base.Therefore, in Electrogenerated chemiluminescent immunoassay instrument, usually
Multiple holding structures (rectangle fixed mechanism or turntable) are set, and one can in tri- dimensions of XYZ independently of one another from
By the mechanical arm moved, which is equipped with sampling probe, so that according to program setting, from each holding structure, (rectangle is solid
Determine mechanism or turntable) on take different reagents to be added to be incubated in cup, and be inserted into after sampling in cleaning current carry out it is clear
Wash.This design prevents the time conflict for pipetting liquid, can meet to automate sample number, test speed and other functions
The demand of the more demanding occasion of degree (such as hospital laboratory and clinical examination center).But this structure design also has it to lack
Point：Since in tri- dimensions of XYZ huge mechanical driving mechanism can be needed by the mechanical arm of free movement independently of one another, and
Multiple holding structures (rectangle fixed mechanism or turntable) also take very big space, and in order to improve test speed and automation journey
Degree, also have a big chunk instrument space be used for store/configure liquid and consumptive material, this causes electrochemical luminescence of the prior art
Immunity analysis instrument is bulky, its design concept is " trading space for time ".This instrument is not easy in space since volume is big
The few place in limited place (such as community hospital, hospital department, emergency ward or operating room) and inspection project uses.
The utility model aims to solve the problem that the above problem.
Utility model content
The first aspect of the utility model provides a kind of rotating disc type Electrogenerated chemiluminescent immunoassay instrument, it includes electrochemistry
Luminous test cell 105, energy driven device 108 drive rotating turntable 100 and at least a sampling probe 107, wherein one
The sampling probe 107 is in fluid communication with the electrochemical luminescence test cell 105, wherein the turntable 100 is equipped with along its circumferential direction
At least two in the following four reagent position in storehouse of distribution：Detection reagent position in storehouse 101, system reagent position in storehouse 102, sample to be tested storehouse
Position 103 and incubation cup position in storehouse 104.
Preferably, there is above-mentioned four kinds of reagent positions in storehouse at the same time on the turntable.
Preferably, also there is through hole 111 on the turntable 100.
Preferably, the turntable 100 is annular shape, and the detection reagent position in storehouse 101, system reagent position in storehouse 102, treat test sample
This position in storehouse 103 and at least two and the through hole 111 being incubated in cup position in storehouse 104 are all located at the inside and outside circle of the annulus
Between annular region on.
Preferably, the sampling probe 107 is connected to by cantilever in the vertical axes of sampling needle assemblies 106, the sampling probe
107 can only move up and down along the vertical axes, or can move up and down along the vertical axes but also be done around institute's vertical axes
Rotary motion.
Preferably, the electrochemical luminescence test cell 105 is placed in inside the circular turntable 100, so that whole
Body instrument is compacter.It is of course also possible to the electrochemical luminescence test cell 105 is placed in outside the circular turntable 100
Portion, and the inside of the turntable 100 is used to accommodate other parts.
Preferably, the number of the turntable 100 is only one.
The rotating disc type electrochemical luminescence that the second aspect of the utility model is related to described in the first aspect of the utility model is exempted from
The characteristics of operating method of epidemic disease analyzer, it is maximum, is to include the following steps：The institute by the rotation of the turntable 100
State at least two in detection reagent position in storehouse 101, system reagent position in storehouse 102, sample to be tested position in storehouse 103 and incubation cup position in storehouse 104
Position in storehouse is placed in the lower section of sampling probe 107 according to setting sequential.
The utility model core point be to the layout of above-mentioned tetra- class position in storehouse of A, B, C and D and the driving structure of sampling probe into
Row improves, without regard to the design of other functional units of Electrogenerated chemiluminescent immunoassay instrument, module and subsystem, therefore,
The concrete structure of other each functional units repeats no more, it is believed that other functional units are same as the prior art or are easy to
Slightly adaptations can be applied in the instrument of the utility model on the basis of existing design.
The design concept of the utility model is " changing space with the time ", in order to reduce equipment instrument as much as possible, accounting for instrument
Certain larger class of device space or a few class reagent containers (such as container of storage A classes and C class I liquid Is) are placed on outside instrument (such as
In refrigerator), according to the actual needs in application-specific place, the position in storehouse for minimum number liquid storage only is set in instrument internal；
The position in storehouse of difference in functionality is merged into a unit at the same time.This design can bring time conflict during sampling, but this conflict
It can be avoided by reducing the test number of unit interval.That is, reduce equipment instrument to sacrifice time and efficiency
To meet that test volume is of less demanding, examine project few, but the application places that the size requirements to instrument are very high.
Considered based on this theory and design, the utility model is different from the key of other Electrogenerated chemiluminescent immunoassay instrument
Technical characteristic is that the plurality of liquid in A, B, C and D class, liquid mixture, liquid/solid mixtures are placed on one to revolve
On the turntable for turning (preferably bidirectional rotation).Fig. 1 is a schematic diagram (being expressed in a manner of top view) of the utility model.Schematic diagram
In turntable 100 there are six detection reagent positions in storehouse 101 (detection reagent for example can be that biotinylated antibody or antigen are molten
Liquid, the antibody or antigenic solution of luminescent label, and bead suspension triplets), two systems agent bin compartment
102 (system reagent is, for example, tripropyl amine (TPA) buffer solution and electrochemical cleaning liquid), five sample positions in storehouse 103 and five incubation cup positions in storehouse
104.As needed, through hole 111 (see Fig. 2) can be further opened up on turntable 100 to wear to allow sampling probe to move up and down
Cross the turntable and cleaned by the water spray of lower part placement or current.The class position in storehouse of described 101,102,103 and 104 4 is circumferentially distributed in
On turntable 100, according to design and it is actually needed, can be set on turntable 100 in position in storehouse 101,102,103 and 104 at least
Two classes.It is preferred that four class positions in storehouse are all set.
Due to storage liquid, liquid mixture, the container of liquid/solid mixtures and reactor shape and differ in size,
Hole (or container placement space) on different classes of position in storehouse is also different in terms of size, geometry and number.Root
According to the usual way of Electrogenerated chemiluminescent immunoassay, the volume of hole (or container placement space) and number should expire on turntable 100
Foot is claimed below：
The detection reagent container that each energy receiving volume of detection reagent position in storehouse 101 is 1 milliliter to 50 milliliters；Each is
The system reagent container that the energy receiving volume of reagent position in storehouse 102 of uniting is 50 milliliters to 500 milliliters；Each sample to be tested position in storehouse 103
The sample container that energy receiving volume is 0.5 milliliter to 20 milliliters；Each be incubated cup position in storehouse 104 can receiving volume for 50 microlitres extremely
500 microlitres of reaction vessel.
Turntable 100 can according to program setting, under rotating driving device 108 (such as motor, gear component) driving into
Row rotates clockwise or counterclockwise, so as to the detection reagent for being placed on detection reagent position in storehouse 101 and be placed on sample to be tested storehouse
The sample of position 103 is placed under sampling probe 107 moving up and down by setting order.Equally, it is placed on to be incubated on cup position in storehouse 104 and uses
It can be also in the incubation cup that liquid is mixed or reacted by the rotation of turntable under sampling probe 107, receive sampling probe by setting
The liquid or liquid/solid mixtures that volume pipettes.It is another in the immune complex that magnetic bead surfaces are formed after incubation process
One (being also designed to same) sampling probe 107 extracts injection electrochemical luminescence measuring unit 105 and measures.The sampling probe 107
It is also used for extracting system reagent (buffer solution and electrochemical cleaning such as containing tripropyl amine (TPA) for being placed on system reagent position in storehouse 102 at the same time
Liquid etc.).
Turntable 100 can be directly placed on a base 109, also can be overhead on base 109 by stent.By
Disposable in being incubated cup, can be placed inside or outside turntable 100 be incubated cup box and set corresponding crawl and
Place and be incubated cup mechanism 112.
The advantages of the utility model, is as follows：
The utility model is to set two on same turntable relative to the greatest improvement point of prior art instrument equipment
Kind and the above different freight spaces, space is exchanged for the time, by turntable rotation by each position in storehouse according to setting sequential as
Below sampling probe, to extract and add reagent, reduce turntable number, it also avoid being so that sampling probe XYZ is three-dimensional originally
The required huge driving mechanism of free movement, therefore, the apparatus structure of the utility model is more compact compact.
Brief description of the drawings
Fig. 1 is the position in storehouse schematic diagram of the rotating disc type Electrogenerated chemiluminescent immunoassay instrument in the utility model.
Fig. 2 is the rotating disc type Electrogenerated chemiluminescent immunoassay instrument schematic diagram that turntable is located on instrument base.
Fig. 3 is turntable mounting higher than the rotating disc type Electrogenerated chemiluminescent immunoassay instrument schematic diagram on base.
Fig. 4 is with the Electrogenerated chemiluminescent immunoassay instrument schematic diagram for being incubated the automatic placement of cup and recovering mechanism.
Each reference numeral implication is as follows：
100 turntables
101 detection reagent positions in storehouse
102 system reagent positions in storehouse
103 sample to be tested positions in storehouse
104 are incubated cup position in storehouse
105 electrochemical luminescence measuring units
106 sampling needle assemblies
107 sampling probes
108 rotating driving devices
109 bases
110 support for rotary disc
111 through holes
112 automatic loadings and unloading are incubated cup mechanism
113 are placed in the incubation cup in box.
Embodiment
Below in conjunction with each attached drawing, clear, complete description is carried out to the technical scheme in the embodiment of the utility model, is shown
So, described embodiment is only the part of the embodiment of the utility model, instead of all the embodiments.Based on this practicality
Embodiment in new, the every other reality that those of ordinary skill in the art are obtained without creative efforts
Example is applied, shall fall within the protection scope of the present invention.
Embodiment 1
A kind of mode for implementing the utility model is to set multiple perforates on the turntable 100 described in utility model content
(or container placement space) forms 101,102,103 and 104 4 class positions in storehouse.The turntable is placed on a base 109, in base
The rotation of turntable 100 is ensured by ball (not shown) between turntable.
The embodiment employs the design of double sampling probes, and a sampling probe 107 is responsible for pipetting the reagent for being positioned over position in storehouse 101
With magnetic bead and the sample of position in storehouse 103 (being blocked in fig. 2, with reference to figure 1), and the material pipetted injection position in storehouse 104 being incubated
Educate cup or reaction cup.It is another in the antibody-antigen-antibody sandwich structure compound that magnetic bead surfaces are formed after the completion of incubation
Sampling probe 107 extracts injection electrochemical luminescence test cell 105, is measured by electrochemical luminescence signals.After test,
Sampling probe 107 extracts and is placed in the system reagent of position in storehouse 102 into the cleaning and regeneration of row test cell 105.
As shown in Fig. 2, to reduce the overall volume of instrument as much as possible, electrochemical luminescence test cell 105 is located at turntable
The inside of ring.But the outside that also electrochemical luminescence test cell can be placed in turret loop according to being actually needed, and by instrument its
Its unit, module or subsystem are placed in the inside of ring.
In the present embodiment, two sampling probes 107 only move up and down.But according to design and it can also be actually needed, will
One of sampling probe or two sampling probes are designed as that sampling can be rotated in a fan section or between different freight spaces and add
The operating mode of sample.This pattern can reduce crosspointer and sample (or sample-adding) time conflict caused by possibility at the same time.
Embodiment 2
The another way for implementing the utility model is to set to place on the turntable 100 described in utility model content to use
In tetra- class I liquid I of A, B, C and D, liquid mixture, liquid/solid mixtures position in storehouse 101,102,103 and 104.And this turn
Disk is overhead on base 109, and turntable is supported by some stents 110 on base.
The embodiment employs the design of double sampling probes, and a sampling probe 107 is responsible for pipetting the A classes for being positioned over position in storehouse 101
The C class samples of reagent and position in storehouse 103, and the material pipetted injection is previously placed among the incubation cup of 104 positions in storehouse on turntable.Incubate
After the completion of educating, note is extracted by another sampling probe 107 in the antibody-antigen-antibody sandwich structure compound that magnetic bead surfaces are formed
Enter electrochemical luminescence test cell 105, measured by electrochemical luminescence signals.After test, sampling probe 107 is extracted and put
In position in storehouse 102 B class system reagents into row test cell 105 cleaning and regeneration.
As shown in figure 3, to reduce the overall volume of instrument as much as possible, electrochemical luminescence test cell 105 is located at turntable
The inside of ring.But electrochemical luminescence test cell can be also placed in the outside of turret loop according to design and being actually needed, and by instrument
Other units, module or the subsystem of device are placed in the inside of ring.
In the present embodiment, two sampling probes 107 only move up and down.But according to design and it can also be actually needed, will
One of sampling probe or two sampling probes are designed as that sampling can be rotated in a fan section or between different freight spaces and add
The operating mode of sample.This pattern can reduce crosspointer and sample (or sample-adding) time conflict caused by possibility at the same time.In another kind
In the case of, it can also use single-needle design.
Embodiment 3
In above-described embodiment 1 and embodiment 2, reaction cup or incubation cup as consumptive material are to be manually placed into its position in storehouse in advance
104.In order to improve efficiency, it can add automatic loading on the basis of embodiment one and embodiment two and unloading be incubated cup
Mechanism 112.
Fig. 4 shows in turntable, arranges neat incubation cup 113 and is incubated cup placement and recovering mechanism 112 automatically.
When multiple samples need to carry out multiple tests, but 104 positions in storehouse not enough use and the time it is urgent when, load and unload using automatic
The designing scheme for being incubated cup mechanism 112 can be in the case where not disturbing the test sample waited on machine, certain
Testing efficiency is lifted in degree.
Equally, which employs the design of double sampling probes, and a sampling probe 107, which is responsible for pipetting, is positioned over position in storehouse 101
A classes reagent and position in storehouse 103 C class samples, and by the material pipetted injection be previously placed in 104 positions in storehouse on turntable incubation cup it
In.After the completion of incubation, taken out in the antibody-antigen-antibody sandwich structure compound that magnetic bead surfaces are formed by another sampling probe 107
Injection electrochemical luminescence test cell 105 is taken, is measured by electrochemical luminescence signals.After test, sampling probe 107 is taken out
Take the cleaning and regeneration for being placed in the B class system reagents of position in storehouse 102 into row test cell 105.
As shown in figure 3, to reduce the overall volume of instrument as much as possible, electrochemical luminescence test cell 105 is located at turntable
The inside of ring.But electrochemical luminescence test cell can be also placed in the outside of turret loop according to design and being actually needed, and by instrument
Other units, module or the subsystem of device are placed in the inside of ring.
In the present embodiment, two sampling probes 107 only move up and down.But according to design and it can also be actually needed, will
One of sampling probe or two sampling probes are designed as that sampling can be rotated in a fan section or between different freight spaces and add
The operating mode of sample.This pattern can reduce crosspointer and sample (or sample-adding) time conflict caused by possibility at the same time.In another kind
In the case of, it can also use single-needle design.
The above is only the preferred embodiment of the utility model only, is not intended to limit the utility model, all at this
Within the spirit and principle of utility model, any modification, equivalent replacement, improvement and so on, should be included in the utility model
Protection domain within.
Claims (7)
1. a kind of rotating disc type Electrogenerated chemiluminescent immunoassay instrument, it includes electrochemical luminescence test cell (105), can be driven by rotation
Dynamic device (108) drives rotating turntable (100) and an at least sampling probe (107), wherein one in the sampling probe (107)
Only it is in fluid communication with the electrochemical luminescence test cell (105), it is characterised in that：The turntable (100) is equipped with along its circumferential direction
At least two in the following four reagent position in storehouse of distribution：Detection reagent position in storehouse (101), system reagent position in storehouse (102), treat test sample
This position in storehouse (103) and incubation cup position in storehouse (104).
2. rotating disc type Electrogenerated chemiluminescent immunoassay instrument according to claim 1, it is characterised in that：The turntable (100)
On also there is through hole (111).
3. rotating disc type Electrogenerated chemiluminescent immunoassay instrument according to claim 2, it is characterised in that：The turntable (100)
For annular shape, the detection reagent position in storehouse (101), system reagent position in storehouse (102), sample to be tested position in storehouse (103) and incubation cup storehouse
At least two and the through hole (111) in position (104) are all located in the annular region between the inside and outside circle of the annulus.
4. rotating disc type Electrogenerated chemiluminescent immunoassay instrument according to claim 1, it is characterised in that：The sampling probe
(107) it is connected to by cantilever in the vertical axes of sampling needle assemblies (106), the sampling probe (107) can only be along the vertical axes
Move up and down, or can move up and down along the vertical axes and by can rotate around institute's vertical axes.
5. rotating disc type Electrogenerated chemiluminescent immunoassay instrument according to claim 3, it is characterised in that：The electrochemical luminescence
It is internal that test cell (105) is placed in the circular turntable (100).
6. rotating disc type Electrogenerated chemiluminescent immunoassay instrument according to claim 1, it is characterised in that：The turntable (100)
Number be only one.
7. rotating disc type Electrogenerated chemiluminescent immunoassay instrument according to claim 1, it is characterised in that：The incubation cup position in storehouse
(104), the number of detection reagent position in storehouse (101), system reagent position in storehouse (102) and sample to be tested position in storehouse (103) is independently of one another
For one or more.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201721163979.XU CN207232181U (en) | 2017-09-12 | 2017-09-12 | A kind of rotating disc type Electrogenerated chemiluminescent immunoassay instrument |
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| CN201721163979.XU CN207232181U (en) | 2017-09-12 | 2017-09-12 | A kind of rotating disc type Electrogenerated chemiluminescent immunoassay instrument |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107449928A (en) * | 2017-09-12 | 2017-12-08 | 深圳安赛诊断技术有限公司 | A kind of rotating disc type Electrogenerated chemiluminescent immunoassay instrument |
| CN113433264A (en) * | 2020-03-23 | 2021-09-24 | 上海烟草集团有限责任公司 | A carousel formula suction equipment for triggering type cigarette |
-
2017
- 2017-09-12 CN CN201721163979.XU patent/CN207232181U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107449928A (en) * | 2017-09-12 | 2017-12-08 | 深圳安赛诊断技术有限公司 | A kind of rotating disc type Electrogenerated chemiluminescent immunoassay instrument |
| CN113433264A (en) * | 2020-03-23 | 2021-09-24 | 上海烟草集团有限责任公司 | A carousel formula suction equipment for triggering type cigarette |
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