CN106860702A - Control Chinese medicine composition, its extract, preparation method and the medicament of self-closing disease - Google Patents

Control Chinese medicine composition, its extract, preparation method and the medicament of self-closing disease Download PDF

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CN106860702A
CN106860702A CN201510916491.9A CN201510916491A CN106860702A CN 106860702 A CN106860702 A CN 106860702A CN 201510916491 A CN201510916491 A CN 201510916491A CN 106860702 A CN106860702 A CN 106860702A
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medicine composition
chinese medicine
preparation
extract
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浦元清
黄烈霞
唐镇生
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The invention discloses a kind of Chinese medicine composition for controlling self-closing disease, its extract, preparation method and medicament.Said composition comprising kuh-seng 20-45 parts, grass-leaved sweetflag 8-15 parts, borneol 1-3 parts, play both sides of the street 8-15 parts, rhizome of chuanxiong 8-15 parts, Radix Astragali 25-35 parts, bighead atractylodes rhizome 8-15 parts, dried orange peel 8-15 parts and rhizoma alismatis 10-15 parts.Said composition preparation method is to mix each component of described Chinese medicine composition；Or after each component of described Chinese medicine composition is mixed, it is fine powder to crush.The preparation method of the extraction includes mixing described Chinese medicine composition with water, decocts, and decoction liquor is obtained after separation of solid and liquid.Chinese medicine composition of the invention and its extract are evident in efficacy in the treatment of self-closing disease, have no toxic side effect and drug dependence, meanwhile, preparation method is simple, convenient to take.

Description

Control Chinese medicine composition, its extract, preparation method and the medicament of self-closing disease
Technical field
The present invention relates to a kind of Chinese medicine composition for controlling self-closing disease, its extract, preparation method and medicament.
Background technology
It is known that self-closing disease is incurable disease, also known as spiritual " cancer ".According to incompletely statistics, whole world self-closing disease patient Have 7,007,000,000, China has 1,003,000,000 or so.Especially China carry out only-child after, to be originally excessive risk man Front yard, even more brings heavy disaster.Because number of the infected is huge, great threat is carried out to mankind's health care belt, while this kind of disease Disease also has the tendency of expansion trend, according to Korean science man research discovery, now many self-closing disease morbidities failed to pinpoint a disease in diagnosis, mistaken diagnosis etc.. According to statistics, slight morbidity number is counted, the morbidity of self-closing disease is up to 1/38th.
In the prior art, the treatment means of self-closing disease mainly have：1st, the traditional Chinese medical science (acupuncture etc.) treatment, takes effect slow, repeats Property is poor, it is difficult to allow autism children to receive and adhere to；2nd, doctor trained in Western medicine (kind stimulant substance, antidepressant, nerve growth factor Deng) treatment, side effect is obvious, and necessary long-term taking, once stopping the state of an illness becoming more serious.Long-term use, except can Cause childhood dystrophy, influence bone growth and growth and development, also the hyperactivity of original possible self-healing can be developed into continuity The spiritual foul disease in all one's life；3rd, psychological intervention, Rehabilitation Training in Treating, psychotherapy etc., simply alleviate symptom for the moment, treat the time one Long, the state of an illness still can rebound, it is necessary to long-term treatment, and slowly effect.In addition, the interference method for the treatment of autism is many at present, but It is the evidence for mostly lacking evidence-based medicine EBM.Optimum treatment method is there is no, optimal treatment method should be the treatment of individuation.Its In, education and training is most effective, topmost treatment method, wherein, " TEACCH educational plans " is effective certainly as one kind Disease therapy is closed, has worldwide been had and has widely been put into practice and obtained extensive approval.Therefore, national self-closing disease patient School for learning disabilities is in full flourish, and due to lacking the management of science, its quality is very different, except it is a small number of have certain qualification in addition to, greatly Many " shaking a meter machine " as money-making.In addition, the charge of China's psychological intervention, Rehabilitation Training in Treating and psychotherapy self-closing disease is compared Height, general family can not still afford.
It can be seen that, current self-closing disease does not have highly effective treatment means, is more preferably used to treat self-closing without a kind of The Chinese medicine of disease.Therefore, this area needs a kind of effective ways for treating self-closing disease, above-mentioned technical problem urgent need to resolve badly.
The content of the invention
The technical problems to be solved by the invention be in order to overcome it is existing treatment self-closing disease medicine in, Western medicine exist Toxic and side effect is big, cures the symptoms, not the disease, and the course for the treatment of that Chinese medicine is present is long, and curative effect is not obvious, and there is not yet effectively treats self-closing The defects such as the Chinese medicine of disease, and provide a kind of Chinese medicine composition for controlling self-closing disease, its extract, preparation method and medicament.This hair Bright Chinese medicine composition and its extract are evident in efficacy in the treatment of self-closing disease, have no toxic side effect and drug dependence, together When, preparation method is simple, convenient to take.
The invention provides a kind of Chinese medicine composition, its component for including following parts by weight：Kuh-seng 20-45 parts, stone Chang Pu 8-15 parts, borneol 1-3 parts, play both sides of the street 8-15 parts, rhizome of chuanxiong 8-15 parts, Radix Astragali 25-35 parts, bighead atractylodes rhizome 8-15 parts, dried orange peel 8-15 parts With rhizoma alismatis 10-15 parts.
In described Chinese medicine composition, it is preferred that the component comprising following parts by weight：Kuh-seng 35-45 parts (preferably 40 Part), grass-leaved sweetflag 8-10 parts, borneol 1-3 parts (preferably 2 parts), play both sides of the street 8-10 parts, rhizome of chuanxiong 8-10 parts, Radix Astragali 30-35 parts, the bighead atractylodes rhizome 10-15 parts, dried orange peel 10-12 parts and rhizoma alismatis 10-12 parts.
Described Chinese medicine composition, it is preferred that it is made up of the component of following parts by weight：Kuh-seng 20-45 parts, grass-leaved sweetflag 8-15 parts, borneol 1-3 parts, play both sides of the street 8-15 parts, rhizome of chuanxiong 8-15 parts, Radix Astragali 25-35 parts, bighead atractylodes rhizome 8-15 parts, dried orange peel 8-15 parts and Rhizoma alismatis 10-15 parts.
Present invention also offers a kind of preparation method of described Chinese medicine composition, it comprises the following steps：Will be described The each component mixing of Chinese medicine composition, you can, or after each component of described Chinese medicine composition is mixed, it is fine powder to crush, .
It is preferred that each component in described Chinese medicine composition directly can also mix as fine powder.
Crushed after the mixing of above-mentioned each component during for fine powder, the method and condition of described crushing can be the conventional side in this area The method such as method and condition, such as dry pulverization process, wet pulverizing, low-temperature grinding and ultra-fine grinding, specific method and condition can bases It is actually needed and is selected, preferably using the method for ultra-fine grinding.After the operation of described crushing terminates, the grain of gained fine powder Footpath can be not especially limited, usually each breaking method conventional particle size to be reached.When the method using ultra-fine grinding, It is preferred that the average diameter of the fine powder of gained is less than 10 μm.
Described Chinese medicine composition can be taken according to the conventional instructions of taking in this area, for example boiling water punching as fine powder Clothes are directly taken in the form of Chinese medical extract.When being taken after mixing it with water with fine powder form boiling water, it is preferred that it is daily 2-3 times, every time 3g。
Chinese medicine composition of the invention can be form of mixtures or the nested form for being divided into some independent components.
Present invention also offers a kind of preparation method of Chinese medical extract, it comprises the following steps：By described Chinese medicine group Compound mixes with water, decocts, and decoction liquor is obtained after separation of solid and liquid, you can.
Described Chinese medicine composition can be not especially limited with water with magnitude relation, be this area conventional amount used, preferably The consumption of water is defined by submerging powder, usually more than 2-3 centimetres of powder.Wherein, the volume mass of water and Chinese medicine composition Than being preferably 5mL/g-15mL/g.
The method of the decoction can be the conventional method of this area decocting for Chinese herbal medicine, be preferably comprised the following steps：Will be described Chinese medicine composition soaked in water 15-30 minutes, first intense fire is fried boiling, then is cooked by slow fire 10-15 minutes, you can.
In decoction process, the operation of stirring preferably can be also further included.The operation of the stirring is mainly and avoids Medicinal material decocts paste, while also improving the decocting rate of Effective Component of Chinese Medicine.Generally every stirring in 5-10 minutes once, 30 are stirred every time - 1 minute second.
The number of times of the decoction can be not especially limited, and generally decoct 1-3 times, and gained decoction liquor is mixed after decocting every time, .If decoction liquor is too many after mixing, the decoction liquor of mixing can again be decocted, be taken again after concentration.
After decoction, gained decoction liquor, every dose of about 50mL-200mL, every dose is daily dose, divides 2-3 times and takes.In principle, Above-mentioned Chinese medical extract (decoction liquor) same day prepares the same day and takes, but in order to convenient to take, can also be prepared on a large scale it is described in Medicament extract, with 20mL-100mL/ bags of packing, when taking, heating.
In a preferred embodiment of the present invention, it is preferred that the Chinese medical extract prepares gained decoction liquor, can also be further Concentrate drying, you can obtain the concentrated extract or concentrate drying powder of the decoction liquor.It is preferred that 60 DEG C -65 DEG C of described concentrated extract Lower relative density is 1.10-1.12.
Present invention also offers a kind of Chinese medical extract, it is prepared by the preparation method of above-mentioned Chinese medical extract.Institute The Chinese medical extract stated can be the decoction liquor after above-mentioned decoction, or be obtained after gained decoction liquor concentrate drying after above-mentioned decoction Concentrated extract or concentrate drying powder.
In the present invention, each component kuh-seng in described Chinese medicine composition, grass-leaved sweetflag, borneol, play both sides of the street, it is rhizome of chuanxiong, the Radix Astragali, white Art, dried orange peel and rhizoma alismatis are Chinese medicine material medicine commonly used in the art.
Present invention also offers a kind of medicament, it includes Chinese medicine composition as described above and/or Chinese medicine as described above Extract.In described medicament, described Chinese medicine composition and/or described Chinese medical extract as active component, its quality Account for the 0.5%-99% of described medicament gross mass.Wherein, it can be the conventional formulation in this area, example that the formulation of described medicament is Such as powder, pill, granule, capsule, tablet or oral liquid.Wherein, powder, pill, granule, capsule, tablet or mouth The preparation method for taking liquid is the conventional preparation method in this area.
Also comprising this area routine in described medicament, with auxiliary material of the inventive compound without antagonism.It is described Auxiliary material refer to the conventional pharmaceutic adjuvant of pharmaceutical field, be to add to solve the mouldability of preparation, validity, stability, security Enter the medicinal material of routine in addition to the active ingredient (s in prescription, such as diluent (such as carboxyrnethyl starch sodium), adhesive (such as PVP Deng), disintegrant (such as microcrystalline cellulose), lubricant (such as magnesium stearate, superfine silica gel powder) and other adjuvants.According to Need, above-mentioned auxiliary material may be selected, by this area conventional method, Chinese medicine composition of the invention is made described medicament.
Treatment and/or prevention are being prepared present invention also offers described Chinese medicine composition or described Chinese medical extract certainly The application closed in the medicine or health products of disease.
In order to reach more preferable curative effect, when using Chinese medicine composition of the invention or extract, can be while partner treatment Health care instrument treats self-closing disease together.The treatment of health care equipment is treatment of health care equipment commonly used in the art, preferably The treatment of health care equipment disclosed in Chinese patent CN202637727U.Here, the application quotes the complete of above-mentioned Chinese patent application Text.
When partner treatment health care instrument treats self-closing disease together, the intrinsic frequency arranges value of described treatment of health care equipment Should be identical with human body brain intrinsic frequency, usually 8-12 hertz (Hz).The treatment time of described treatment of health care equipment is general It is 2-4 hours/day, preferably morning 1-2 hours, 1-2 hours afternoon.
The treatment cycle of self-closing disease is general more than one month, can suitably be adjusted depending on state of an illness difference.
Without prejudice to the field on the basis of common sense, above-mentioned each optimum condition, can be combined, and obtain final product the present invention each preferably Example.
Agents useful for same of the present invention and raw material are commercially available.
Positive effect of the invention is：
Chinese medicine composition of the invention and its extract are evident in efficacy in the treatment of self-closing disease, have no toxic side effect and medicine Thing dependence, meanwhile, preparation method is simple, convenient to take.
Specific embodiment
The present invention is further illustrated below by the mode of embodiment, but does not therefore limit the present invention to described reality Apply among a scope.The experimental technique of unreceipted actual conditions in the following example, conventionally and condition, or according to business Product specification is selected.
In following embodiments, the average diameter of superfine powder is below 10 μm.
Embodiment 1
Weigh kuh-seng 20g, grass-leaved sweetflag 8g, borneol 1g, the 8g that plays both sides of the street, rhizome of chuanxiong 8g, Radix Astragali 25g, bighead atractylodes rhizome 8g, dried orange peel 8g and pool 10g mixing is rushed down, using superfine grinding method, it is superfine powder that above-mentioned Chinese medicine composition is crushed, you can.
Embodiment 2
Weigh kuh-seng 45g, grass-leaved sweetflag 15g, borneol 3g, the 15g that plays both sides of the street, rhizome of chuanxiong 15g, Radix Astragali 35g, bighead atractylodes rhizome 15g, dried orange peel 15g and rhizoma alismatis 15g mixes, and using the method for ultra-fine grinding, it is superfine powder that above-mentioned Chinese medicine composition is crushed, you can.
Embodiment 3
Weigh kuh-seng 35g, grass-leaved sweetflag 8g, borneol 2g, the 8g that plays both sides of the street, rhizome of chuanxiong 8g, Radix Astragali 30g, bighead atractylodes rhizome 10g, dried orange peel 10g and Rhizoma alismatis 10g mixes, and using the method for ultra-fine grinding, it is superfine powder that above-mentioned Chinese medicine composition is crushed, you can.
Embodiment 4
Weigh kuh-seng 45g, grass-leaved sweetflag 10g, borneol 2g, the 10g that plays both sides of the street, rhizome of chuanxiong 10g, Radix Astragali 35g, bighead atractylodes rhizome 15g, dried orange peel 12g and rhizoma alismatis 12g mixes, and using the method for ultra-fine grinding, it is superfine powder that above-mentioned Chinese medicine composition is crushed, you can.
Embodiment 5
Weigh kuh-seng 20g, grass-leaved sweetflag 8g, borneol 1g, the 8g that plays both sides of the street, rhizome of chuanxiong 8g, Radix Astragali 25g, bighead atractylodes rhizome 8g, dried orange peel 8g and pool 10g mixing is rushed down, plus 500mL water soaks 15 minutes, first intense fire is fried boiling, then is cooked by slow fire 10 minutes, filtering, takes decoction liquor, you can. When decocting, every stirring in 5 minutes once, it is to avoid medicinal material decocts paste.Take for convenience, by 50mL/ bags of bag of pan-fried well-done liquid point Dress, heating can take.
Embodiment 6
Weigh kuh-seng 35g, grass-leaved sweetflag 8g, borneol 2g, the 8g that plays both sides of the street, rhizome of chuanxiong 8g, Radix Astragali 30g, bighead atractylodes rhizome 10g, dried orange peel 10g and Rhizoma alismatis 10g mix, plus 1000mL water soak 30 minutes, first intense fire is fried boiling, then is cooked by slow fire 15 minutes, filtering, take decoction liquor (in Medicament extract), you can.When decocting, every stirring in 5 minutes once, it is to avoid medicinal material decocts paste.Take for convenience, it is well-done by decocting 100mL/ bags of packaging of liquid (Chinese medical extract) point, heating can take.
Embodiment 7
Weigh kuh-seng 45g, grass-leaved sweetflag 10g, borneol 2g, the 10g that plays both sides of the street, rhizome of chuanxiong 10g, Radix Astragali 35g, bighead atractylodes rhizome 15g, dried orange peel 12g and rhizoma alismatis 12g mixes, plus 1500mL water soaks 30 minutes, and first intense fire is fried boiling, then is cooked by slow fire 15 minutes, filtering, takes decoction Liquid, you can.When decocting, every stirring in 5 minutes once, it is to avoid medicinal material decocts paste.Take for convenience, by pan-fried well-done liquid point 100mL/ bags of packaging, heating can take.
Embodiment 8
Weigh kuh-seng 40g, grass-leaved sweetflag 10g, borneol 2g, the 10g that plays both sides of the street, rhizome of chuanxiong 10g, Radix Astragali 35g, bighead atractylodes rhizome 15g, dried orange peel 12g and rhizoma alismatis 12g mixes, plus 1500mL water soaks 30 minutes, and first intense fire is fried boiling, then is cooked by slow fire 15 minutes, filtering, takes decoction Liquid, you can.When decocting, every stirring in 5 minutes once, it is to avoid medicinal material decocts paste.Gained decoction liquor is concentrated under reduced pressure, when dense Contracting liquid 60 DEG C measure relative density for 1.10 when, stop concentration, obtain final product concentrated extract.
Embodiment 9
Weigh kuh-seng 40g, grass-leaved sweetflag 12g, borneol 2g, the 12g that plays both sides of the street, rhizome of chuanxiong 10g, Radix Astragali 35g, bighead atractylodes rhizome 15g, dried orange peel 10g and rhizoma alismatis 10g mixes, plus 1500mL water soaks 30 minutes, and first intense fire is fried boiling, then is cooked by slow fire 15 minutes, filtering, takes decoction Liquid, you can.When decocting, every stirring in 5 minutes once, it is to avoid medicinal material decocts paste.Gained decoction liquor be concentrated under reduced pressure into it is dry, Obtain final product concentrate drying powder.
Embodiment 10
By concentrate drying powder obtained in embodiment 9, it is well mixed with Icing Sugar and dextrin, concentrate drying powder, Icing Sugar and dextrin Mass ratio be 1:3:1；Ethanol is added, the softwood of " hand pinches agglomerating, and pressure is to dissipate " is made, then 20 mesh sieves are passed through with fashion of extrusion Net, is made single-size.Dried at 60 DEG C, whole grain, obtain final product the granule containing Chinese medical extract of the present invention.
Embodiment 11
By concentrate drying powder obtained in embodiment 9, it is well mixed with Icing Sugar and dextrin, concentrate drying powder, Icing Sugar and dextrin Mass ratio be 1:3:1；Ethanol is added, the softwood of " hand pinches agglomerating, and pressure is to dissipate " is made, then 20 mesh sieves are passed through with fashion of extrusion Net, is made single-size.Dried at 60 DEG C, whole grain, obtain particle 10g, add magnesium stearate 1g, compressing tablet to obtain final product containing in the present invention The tablet of medicament extract.
Effect example
(1) treatment group：10 self-closing disease patients are selected, patient age is maximum 10 years old, minimum 6 years old, man 5, female 5, disease Journey is most long 7 years, most short 3 years.
(2) treatment method：Chinese medicine composition superfine powder obtained in embodiment 1 is taken by treatment group, daily 2-3 times, each 3g, Boiling water is taken after mixing it with water, and the course for the treatment of is accordingly adjusted depending on the state of an illness.
(3) curative effect judging standard：
Clinical cure：Clinical symptom disappearance；
It is effective：Clinical symptoms are obviously improved；
Take a turn for the better：Clinical symptoms take a turn for the better；
It is invalid：Clinical symptoms are without change.
The treatment group's efficacy result of table 1
In following model cases, each component and consumption are referring to above-described embodiment 4 in the Chinese medicine composition superfine powder taken. When partner treatment health care instrument treats self-closing disease together, the intrinsic frequency arranges value for the treatment of of health care equipment is 8-12 hertz (Hz). The treatment time for the treatment of of health care equipment is generally 2-4 hours/day, preferably morning 1-2 hours, 1-2 hours afternoon.
Model case 1
Slowly, man, 8 years old, self-closing disease is diagnosed as by Shanghai Spirit health center.He is except being enclosed in the world of oneself not Can be outer with people's contacts, it is exactly abnormal excitement that he has a symptom for making one to be difficult to receive, and can scream ten or twenty in one minute, Day and night it is not always the case.In the dead of night by he cry the whole family must not sleep peacefully, travel around the country seek medical advice it is all invalid, used up it is all of in family Savings, great predicament is brought to family.By taking Chinese medicine composition of the invention, while with the treatment of health care equipment that closes Treatment, it is important that head.After the treatment of continuous ten days, patient's excitement in the past totally disappeared, and no longer sending makes one horrent point Cry a, night sleeps big daybreak.
Through treatment after a while, patient quiets down study now, for example, learn to read with the aid of pictures, and sings nursery rhymes etc., has once in a while Vexed sound, but no longer scream.Simultaneously with the interactive instruction for also becoming many, and listening people around of household, sometimes can also actively with People exchanges.
In addition, by taking Chinese medicine composition of the invention, while with treatment of health care equipment treatment of closing, it is self-closing to three Disease patient continuously treats four months, tentatively changes " the natural kingdom " being enclosed in self world, can receive the instruction of household. This three patients have entered a school reading after tracking 2 years.
Model case 2
Small jade (assumed name), female seven years old, self-closing disease was diagnosed as before 2 years by Shanghai Mental Health Center.Will not be handed over people Stream, look hinders, is enclosed in the world of self late.By taking Chinese medicine composition of the invention, while with the treatment and health that closes After instrument treatment one month, can be exchanged with people, be greatly improved, and family members enquirement or requirement, will soon return Answer or react.Family members says that teach her to become literate in the past, each word is taught seven, eight times can just be remembered；First and second can be only taught now Just remember.Up to the present, known four, 500 words, phonetic also can, and poem can be carried on the back.
In addition, during one's sickness, a small beautiful also strange symptom is afraid of the sound.Number voice is heard, such as bird cries, she Meeting hand as very frightened goes to seal ear.Present these symptoms are also wholly absent.
Model case 3
Xiao Ming (assumed name), man, seven years old.Doubtful self-closing disease was diagnosed as by Shanghai City Children Hospital before 2 years.Patient is constantly Run and jump, constantly stir, also to climb in turn sometimes, move situation extremely serious more.He talks and speaks with a lisp, at all cannot be with People is interactive.It is at home vexed skin, around turns over thing, misses potter the water for playing flowing, unrestrained Kingsoft of water that family often does with him. He cannot contact with anyone, you said with him it is various, be all one answer：Do not want.He has extremely abundant imagination, His mother has bought a set of building blocks to him, and he never takes according to the requirement of regulation, and he did not read English, can but take out various English Word is female next, or even also takes Chu Liao robots, very true to nature.He has fabulous memory function to road, what his father specially opened His automobile route have at fingertips, once having opened an other road, he can kyoodle.
By taking Chinese medicine composition of the invention, while after being treated ten days with the treatment of health care equipment that closes, patient moves more Disease is greatly taken on a new look, and can lie two hours, while various many dynamic performances are also greatly taken on a new look at home, and can be exchanged with people, Observation surrounding, accepts some instructions of people around.

Claims (9)

1. a kind of Chinese medicine composition, it is characterised in that its component for including following parts by weight：Kuh-seng 20-45 parts, grass-leaved sweetflag 8- 15 parts, borneol 1-3 parts, play both sides of the street 8-15 parts, rhizome of chuanxiong 8-15 parts, Radix Astragali 25-35 parts, bighead atractylodes rhizome 8-15 parts, dried orange peel 8-15 parts and pool Rush down 10-15 parts.
2. in Chinese medicine composition as claimed in claim 1, it is characterised in that its component for including following parts by weight：Kuh-seng 35-45 parts, grass-leaved sweetflag 8-10 parts, borneol 1-3 parts, play both sides of the street 8-10 parts, rhizome of chuanxiong 8-10 parts, Radix Astragali 30-35 parts, bighead atractylodes rhizome 10-15 Part, dried orange peel 10-12 parts and rhizoma alismatis 10-12 parts.
3. a kind of preparation method of Chinese medicine composition as claimed in claim 1 or 2, it is characterised in that it comprises the following steps： The each component of described Chinese medicine composition is mixed, you can；Or after each component of described Chinese medicine composition is mixed, crush It is fine powder, you can；Wherein, each component in described Chinese medicine composition directly can also mix as fine powder.
4. a kind of preparation method of Chinese medical extract, it comprises the following steps：By Chinese traditional medicine composition as claimed in claim 1 or 2 Thing mixes with water, decocts, and decoction liquor is obtained after separation of solid and liquid, you can.
5. preparation method as claimed in claim 4, it is characterised in that the volume matter of described water and described Chinese medicine composition Amount is than being 5mL/g-15mL/g；And/or, described decoction comprises the following steps：Described Chinese medicine composition is soaked in water 15-30 minutes, first intense fire was fried boiling, then was cooked by slow fire 10-15 minutes, you can；And/or, described preparation method is also further wrapped The step of containing gained decoction liquor is carried out into concentrate drying, obtain the concentrated extract or concentrate drying powder of the decoction liquor；It is preferred that institute Relative density is 1.10-1.12 at 60 DEG C -65 DEG C of the concentrated extract stated.
6. a kind of Chinese medical extract, it is characterised in that it is prepared by the preparation method of claim 4 or 5.
7. a kind of medicament, it is characterised in that it includes Chinese medicine composition as claimed in claim 1 or 2 and/or such as claim 6 Described Chinese medical extract.
8. medicament as claimed in claim 7, it is characterised in that described Chinese medicine composition and/or described Chinese medical extract Used as active component, its quality accounts for more than the 0.5% of described medicament gross mass, preferably 0.5%-99%；And/or, institute The formulation of the medicament stated is powder, pill, granule, capsule, tablet or oral liquid.
9. a kind of Chinese medicine composition as claimed in claim 1 or 2 or Chinese medical extract as claimed in claim 6 are controlled in preparation Treat and/or prevent the application in the medicine or health products of self-closing disease.
CN201510916491.9A 2015-12-10 2015-12-10 Control Chinese medicine composition, its extract, preparation method and the medicament of self-closing disease Pending CN106860702A (en)

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