CN101549085A - Traditional Chinese medicine for treating neurasthenia and preparation method thereof - Google Patents
Traditional Chinese medicine for treating neurasthenia and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating neurasthenia and a preparation method thereof, and the active ingredients of the traditional Chinese medicine are prepared by extracting more than ten medicinal materials of membranous milkvetch root, pilose Asiabell root, stir-fried largehead atractylodes rhizome, tangerine peel, Chinese angelica, Indian bread with pine, stir-fried date seed, thinleaf milkwort root-bark, platycladi seed, dried longan pulp, arisaema cum bile, crateagus pinnatifida, costustoot, honey-fried licorice root, raw oyster shell, spina date seed, common anemarrhena rhizome, oriental waterplantain rhizome and the like. The unique medicinal active ingredients in the traditional Chinese medicine have the efficacies of invigorating heart and spleen, nourishing blood and tranquillization. The traditional Chinese medicine is used for improving insomnia, forgetfulness, failure of memory, fatigue, weakness, dizziness, palpitation and other neurasthenia-like symptoms.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to a kind of neurasthenic Chinese medicine and preparation method thereof that is used for.
Technical background
The neurasthenia is a kind of neurosis disorder, and it is tired easily mainly to show as easy excitement of spirit and mentality, emotion worry, difficulty falling asleep.The patient who has also shows as headache, giddy, dim eyesight, tinnitus, cardiopalmus, breathes hard, sexual impotence, premature ejaculation or menoxenia.The neurasthenia is a kind of slight psychosis, is neurosal a kind of.China psychologic medicine man thinks that through secular investigation the neurasthenia is a kind of neurosis disorder, and it is tired easily mainly to show as easy excitement of spirit and mentality, emotion worry, difficulty falling asleep.The patient who has also shows as headache, giddy, dim eyesight, tinnitus, cardiopalmus, breathes hard, sexual impotence, premature ejaculation or menoxenia.
The neurasthenia is a kind of slight psychosis, is neurosal a kind of." Chinese neural psychiatric department magazine " editorial board in 1985 in " diagnostic criteria of neurosis clinical position ", rewritten neurosal definition " neurosis refers to one group of mental disorder, by sense of discomfort various bodies or spirit, intensive intrapsychic conflict or depression experience worries.Its pathology is not tested normal continuing and is existed or occur repeatedly, but lacks any provable organic basis; The patient tries hard to break away from, and is powerless." neurasthenia also meets These characteristics, patient does not have organic disease, normal for insomnia, mental deficiency, anxious state of mind symptom that can not be autonomous such as big worries.But neurasthenic patient does not have serious conduct disorder, and this and serious psychosis such as schizophrenia are distinguishing.
In general, patient neurasthenia has persistent nervous and stress more before ill, and it is bad to worry to take an examination as the student, man and wife, mother-in-law and daughter-in-law's strained relations, and personal lifestyle environment, rule of life drastic change etc., all the possibility inducing neural is weak.
Because mental burden is overweight, do not note striking a proper balance between work and rest, mental work is overtired, and the neurasthenia can be taken place.Primary disease is more common in the brain worker, and cardinal symptom is mental tired easily with muscle power, and work is gone down with the learning efficiency, normal companion's insomnia, absent minded, worried, performance such as feel dizzy.
The neurasthenia is a kind of commonly encountered diseases, and various places all over the world occupy various neurosal first places.The prevalence of urban district, Tianjin primary disease is 9.1%.Guizhou Province finds that after rural survey prevalence is higher, reaches 70.69%o.Because the main feature of primary disease is brain higher nervous center and neuro vegetative functional disorder, so the patient not only has the symptom of brain dysfunctions such as headache, giddy, insomnia and hypomnesis, but also can occur circulating, the symptom of functional disorder such as digestion, endocrine, metabolism and reproductive system.Patient's subjective symptoms is various, and spiritual negative twist is extremely heavy, and many people have obeyed many nourishing medicines, still can not get ideal curative effect, thereby worries that what serious disease is not found out, and the thought worries are checked everywhere and sought medical advice, and have wasted many medicines, time and money.
Neurastheniac is owing to identify oneself to be possessed by the demon of disease for a long time, thus nervous, burnt empty, worried, do not have enough sleep, inappetence, immunologic function degression, also can concurrent other diseases.Not only seriously influence study, work and future, also increased burden, even influence the harmony of family to family.And, constitute new socio-psychological factors again to the worry and the family friction of disease, individual future, and disease is further increased the weight of, form the vicious cycle of pathology, influence the prognosis of disease.
Therefore, though this sick life that does not jeopardize the patient of neurasthenia does not influence the life-span, influenced people's physical and mental health and orthobiosis to a certain extent.
Although it is a lot of to treat neurasthenic Western medicine at present, these medicines also have obvious effect to anxiety reduction, calmness, improvement sleep etc.If but the long-term or excessive use of the tranquilizer of much sleeping peacefully also easily forms dependency and the generation drug resistance of human body to medicine, also has certain side effect.Many patients wish to adhere to for a long time taking that some side effect are little, the reliable Chinese patent medicine of curative effect.
Summary of the invention:
One of purpose of the present invention provides a kind of neurasthenic Chinese medicine that is used for.
Another object of the present invention provides this preparation method of Chinese medicine.
Chinese medicine of the present invention is made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made (part is unit of weight) by following raw materials according:
1. write out a prescription:
Radix Astragali 100-300 part Radix Codonopsis 100-300 part Rhizoma Atractylodis Macrocephalae (parched) 80-240 part
Pericarpium Citri Reticulatae 80-240 part Radix Angelicae Sinensis 80-240 part Poria cum Radix Pini 100-300 part
Semen Ziziphi Spinosae (parched) 100-300 part Radix Polygalae 80-240 part Semen Platycladi 80-240 part
Arillus Longan 100-300 part Arisaema Cum Bile 80-240 part crataegus pin natifida var. Major 100-300 part
Radix Aucklandiae 50-150 part Radix Glycyrrhizae Preparata 50-150 part Concha Ostreae 80-240 part
Semen Ziziphi Spinosae 80-240 part Rhizoma Anemarrhenae 50-150 part Rhizoma Alismatis 80-240 part
The active component that preferred following raw materials according is made, curative effect is better:
120 parts of 150 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 150 parts of Radix Codonopsis of the Radix Astragali
150 parts of 120 parts of Poria cum Radix Pinis of 120 parts of Radix Angelicae Sinensis of Pericarpium Citri Reticulatae
120 parts of 120 parts of Semen Platycladi of 150 parts of Radix Polygalaes of Semen Ziziphi Spinosae (parched)
150 parts of 120 parts of crataegus pin natifida var. Major of 150 parts of Arisaema Cum Bile of Arillus Longan
120 parts of 100 parts of Concha Ostreae of 50 parts of Radix Glycyrrhizae Preparatas of the Radix Aucklandiae
120 parts of 50 portions of Rhizoma Alismatis of 120 parts of Rhizoma Anemarrhenaes of Semen Ziziphi Spinosae
The active ingredient preparation method of Chinese medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.
The following preparation method preparation of preferred employing:
2. preparation technology
(1) Radix Astragali, Radix Codonopsis add 75% alcohol dipping three times, flood 48 hours for the first time, and second and third time flooded respectively 24 hours, filter, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Rhizoma Atractylodis Macrocephalae (parched)s, Pericarpium Citri Reticulatae, Radix Angelicae Sinensis, Poria cum Radix Pini, Semen Ziziphi Spinosae (parched), Radix Polygalae, Semen Platycladi, Arillus Longan, Arisaema Cum Bile, crataegus pin natifida var. Major, the Radix Aucklandiae, Radix Glycyrrhizae Preparata, Concha Ostreae, Semen Ziziphi Spinosae, the Rhizoma Anemarrhenae, Rhizoma Alismatis add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, be ground into fine powder, add acceptable accessories and make different preparations such as granule, sheet, capsule.
Adopt mutual compatibility of above-mentioned raw material of Chinese medicine and preparation method thereof, full side has invigorating the heart and spleen, the effect of nourishing blood to tranquillize the mind.Be used for insomnia forgetfulness, hypomnesis, fatigue and weakness, the improvement of neurasthenia symptoms such as dizzy cardiopalmus.
By the following examples technical scheme of the present invention is described further.
Embodiment 1: the preparation method of granule
1. write out a prescription:
120 parts of 150 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 150 parts of Radix Codonopsis of the Radix Astragali
150 parts of 120 parts of Poria cum Radix Pinis of 120 parts of Radix Angelicae Sinensis of Pericarpium Citri Reticulatae
120 parts of 120 parts of Semen Platycladi of 150 parts of Radix Polygalaes of Semen Ziziphi Spinosae (parched)
150 parts of 120 parts of crataegus pin natifida var. Major of 150 parts of Arisaema Cum Bile of Arillus Longan
120 parts of 100 parts of Concha Ostreae of 50 parts of Radix Glycyrrhizae Preparatas of the Radix Aucklandiae
120 parts of 50 portions of Rhizoma Alismatis of 120 parts of Rhizoma Anemarrhenaes of Semen Ziziphi Spinosae
2. preparation technology
(1) Radix Astragali, Radix Codonopsis add 75% alcohol dipping three times, flood 48 hours for the first time, and second and third time flooded respectively 24 hours, filter, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Rhizoma Atractylodis Macrocephalae (parched)s, Pericarpium Citri Reticulatae, Radix Angelicae Sinensis, Poria cum Radix Pini, Semen Ziziphi Spinosae (parched), Radix Polygalae, Semen Platycladi, Arillus Longan, Arisaema Cum Bile, crataegus pin natifida var. Major, the Radix Aucklandiae, Radix Glycyrrhizae Preparata, Concha Ostreae, Semen Ziziphi Spinosae, the Rhizoma Anemarrhenae, Rhizoma Alismatis add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, add cane sugar powder, mixing is made granule, drying, promptly.
Embodiment 2: the preparation method of tablet
1. write out a prescription:
120 parts of 150 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 150 parts of Radix Codonopsis of the Radix Astragali
150 parts of 120 parts of Poria cum Radix Pinis of 120 parts of Radix Angelicae Sinensis of Pericarpium Citri Reticulatae
120 parts of 120 parts of Semen Platycladi of 150 parts of Radix Polygalaes of Semen Ziziphi Spinosae (parched)
150 parts of 120 parts of crataegus pin natifida var. Major of 150 parts of Arisaema Cum Bile of Arillus Longan
120 parts of 100 parts of Concha Ostreae of 50 parts of Radix Glycyrrhizae Preparatas of the Radix Aucklandiae
120 parts of 50 portions of Rhizoma Alismatis of 120 parts of Rhizoma Anemarrhenaes of Semen Ziziphi Spinosae
2. preparation technology
(1) Radix Astragali, Radix Codonopsis add 75% alcohol dipping three times, flood 48 hours for the first time, and second and third time flooded respectively 24 hours, filter, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Rhizoma Atractylodis Macrocephalae (parched)s, Pericarpium Citri Reticulatae, Radix Angelicae Sinensis, Poria cum Radix Pini, Semen Ziziphi Spinosae (parched), Radix Polygalae, Semen Platycladi, Arillus Longan, Arisaema Cum Bile, crataegus pin natifida var. Major, the Radix Aucklandiae, Radix Glycyrrhizae Preparata, Concha Ostreae, Semen Ziziphi Spinosae, the Rhizoma Anemarrhenae, Rhizoma Alismatis add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, pulverize, sieve, add starch, magnesium stearate, tabletting, promptly.
Embodiment 3: the preparation method of capsule
1. write out a prescription:
120 parts of 150 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 150 parts of Radix Codonopsis of the Radix Astragali
150 parts of 120 parts of Poria cum Radix Pinis of 120 parts of Radix Angelicae Sinensis of Pericarpium Citri Reticulatae
120 parts of 120 parts of Semen Platycladi of 150 parts of Radix Polygalaes of Semen Ziziphi Spinosae (parched)
150 parts of 120 parts of crataegus pin natifida var. Major of 150 parts of Arisaema Cum Bile of Arillus Longan
120 parts of 100 parts of Concha Ostreae of 50 parts of Radix Glycyrrhizae Preparatas of the Radix Aucklandiae
120 parts of 50 portions of Rhizoma Alismatis of 120 parts of Rhizoma Anemarrhenaes of Semen Ziziphi Spinosae
2. preparation technology
(1) Radix Astragali, Radix Codonopsis add 75% alcohol dipping three times, flood 48 hours for the first time, and second and third time flooded respectively 24 hours, filter, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Rhizoma Atractylodis Macrocephalae (parched)s, Pericarpium Citri Reticulatae, Radix Angelicae Sinensis, Poria cum Radix Pini, Semen Ziziphi Spinosae (parched), Radix Polygalae, Semen Platycladi, Arillus Longan, Arisaema Cum Bile, crataegus pin natifida var. Major, the Radix Aucklandiae, Radix Glycyrrhizae Preparata, Concha Ostreae, Semen Ziziphi Spinosae, the Rhizoma Anemarrhenae, Rhizoma Alismatis add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, pulverize, sieve, add starch, mixing is made granule, and drying incapsulates, promptly.
Claims (5)
1, a kind ofly be used for neurasthenic Chinese medicine, it is characterized in that being made up of active ingredient and/or pharmaceutically acceptable carrier, wherein said active ingredient is made by following raw materials according:
Radix Astragali 100-300 part Radix Codonopsis 100-300 part Rhizoma Atractylodis Macrocephalae (parched) 80-240 part
Pericarpium Citri Reticulatae 80-240 part Radix Angelicae Sinensis 80-240 part Poria cum Radix Pini 100-300 part
Semen Ziziphi Spinosae (parched) 100-300 part Radix Polygalae 80-240 part Semen Platycladi 80-240 part
Arillus Longan 100-300 part Arisaema Cum Bile 80-240 part crataegus pin natifida var. Major 100-300 part
Radix Aucklandiae 50-150 part Radix Glycyrrhizae Preparata 50-150 part Concha Ostreae 80-240 part
Semen Ziziphi Spinosae 80-240 part Rhizoma Anemarrhenae 50-150 part Rhizoma Alismatis 80-240 part.
2, a kind of neurasthenic Chinese medicine that is used for according to claim 1 is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:
120 parts of 150 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 150 parts of Radix Codonopsis of the Radix Astragali
150 parts of 120 parts of Poria cum Radix Pinis of 120 parts of Radix Angelicae Sinensis of Pericarpium Citri Reticulatae
120 parts of 120 parts of Semen Platycladi of 150 parts of Radix Polygalaes of Semen Ziziphi Spinosae (parched)
150 parts of 120 parts of crataegus pin natifida var. Major of 150 parts of Arisaema Cum Bile of Arillus Longan
120 parts of 100 parts of Concha Ostreae of 50 parts of Radix Glycyrrhizae Preparatas of the Radix Aucklandiae
120 parts of 50 portions of Rhizoma Alismatis of 120 parts of Rhizoma Anemarrhenaes of Semen Ziziphi Spinosae.
3, according to the described a kind of neurasthenic Chinese medicine that is used for of claim 1-2, it is characterized in that adopting following method to make:
(1) Radix Astragali, Radix Codonopsis add 75% alcohol dipping three times, flood 48 hours for the first time, and second and third time flooded respectively 24 hours, filter, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Rhizoma Atractylodis Macrocephalae (parched)s, Pericarpium Citri Reticulatae, Radix Angelicae Sinensis, Poria cum Radix Pini, Semen Ziziphi Spinosae (parched), Radix Polygalae, Semen Platycladi, Arillus Longan, Arisaema Cum Bile, crataegus pin natifida var. Major, the Radix Aucklandiae, Radix Glycyrrhizae Preparata, Concha Ostreae, Semen Ziziphi Spinosae, the Rhizoma Anemarrhenae, Rhizoma Alismatis add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, be ground into fine powder, add acceptable accessories and make different preparations such as granule, sheet, capsule.
4, according to any one described a kind of neurasthenic Chinese medicine that is used among the claim 1-3, it is characterized in that this Chinese medicine composition is an oral formulations.
5, according to the described a kind of neurasthenic Chinese medicine that is used for of claim 3-4, it is characterized in that this Chinese medicine composition can be made into granule, capsule, tablet.
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| CNA200810103425XA CN101549085A (en) | 2008-04-03 | 2008-04-03 | Traditional Chinese medicine for treating neurasthenia and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102370779A (en) * | 2010-08-17 | 2012-03-14 | 康达生命科学有限公司 | Preparation method of flos longan extract having nerve protection effects |
| CN104189214A (en) * | 2014-09-29 | 2014-12-10 | 洛阳御平国生物科技有限公司 | Formula for treating neurasthenia |
| CN105287994A (en) * | 2014-05-29 | 2016-02-03 | 李益坤 | Medicine for treating neurasthenia |
| CN105687701A (en) * | 2016-04-21 | 2016-06-22 | 河南中医学院 | Traditional Chinese medicine for treating neurasthenia insomnia |
| CN106389967A (en) * | 2016-12-13 | 2017-02-15 | 徐洪安 | Medicine for treating neurasthenia and preparation method thereof |
-
2008
- 2008-04-03 CN CNA200810103425XA patent/CN101549085A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102370779A (en) * | 2010-08-17 | 2012-03-14 | 康达生命科学有限公司 | Preparation method of flos longan extract having nerve protection effects |
| CN105287994A (en) * | 2014-05-29 | 2016-02-03 | 李益坤 | Medicine for treating neurasthenia |
| CN104189214A (en) * | 2014-09-29 | 2014-12-10 | 洛阳御平国生物科技有限公司 | Formula for treating neurasthenia |
| CN105687701A (en) * | 2016-04-21 | 2016-06-22 | 河南中医学院 | Traditional Chinese medicine for treating neurasthenia insomnia |
| CN106389967A (en) * | 2016-12-13 | 2017-02-15 | 徐洪安 | Medicine for treating neurasthenia and preparation method thereof |
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Open date: 20091007 |