CN106860054A - Composite skin care product and preparation method thereof, skin care item gel and preparation method thereof - Google Patents
Composite skin care product and preparation method thereof, skin care item gel and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The present invention relates to a kind of skin care item gel and preparation method thereof, and in particular to a kind of gel containing anthocyanins pigment from purple sweet potato monomer and preparation method.The gel is by 15~20 parts of the anthocyanin monomer of weight portion, 3~5 parts of glycerine, 2.5~5 parts of butanediol, 1~2 part of beta glucan, 0.3~2 part of carrageenan sodium, 5 2~4 parts of Matrixyl, 0.3~1 part of hyaluronic acid, 0.9~1.5 part of dipotassium glycyrrhizinate, 3~5 parts of glutathione, 0.3~2 part of Carbomer, 0.5~1 part of triethanolamine, 50~70 parts of compositions of 3~4 parts of 1,2 pentanediol and deionized water.The skin care item gel have improve skin ageing, improve wrinkle and color spot, and anthocyanin monomer stabilization, can long-term storage, be conducive to keep effect.
Description
Technical field
The invention belongs to cosmetic field, it is related to a kind of composite skin care product and preparation method thereof, and in particular to Yi Zhonghan
There are the gel and preparation method of anthocyanin monomer.
Background technology
In recent years, the anti-oxidant class skin care item of skin gradually receive the concern of dermatologist and consumer and like.Cause
Human body can be induced for city environmental pollution, for a long time using portable computer, bad daily life system, stress, solar irradiation
Produce substantial amounts of free radical.Free radical can attack the macromolecular substances such as the Skin Cell of health, destruction nucleic acid, protein, draw
Skin Cell membrane lipids peroxidating is played, changes skin cell metabolism and functional form, so as to upset normal skin function.For a long time
Radical damage can make skin produce aging sign, such as：It is light line, wrinkle, pigmentation, lax.Generally, anti-oxidant class skin care
Product contain antioxidant, can neutralize free radical molecule, and reduction is oxidized skin, and the Skin Cell that protects the health is from free radical
Oxidative damage, improves aging sign, such as：Pigmentation is reduced, light crenulation line is smoothed, is compacted.At present, most of antioxygens on the market
Change skin care item and all use vitamin E and vitamin C as antioxidant.But the antioxidant effect of injection Vitamin B_6 is not special
Substantially, skin ageing sign can not be effectively improved.Meanwhile, using injection Vitamin B_6 anti-oxidant skin care item more use Essence
Form, this form can influence consumer to use comfort, feel greasy and slightly skin stimulates.
Anthocyanins pigment from purple sweet potato monomer (hereinafter referred to as " anthocyanin monomer ") is the secondary metabolism thing in plant, belongs to flavonoids
Polyphenolic substance, is mainly enriched in the tubers position of plant, oxidative damage of the protection plant tissue from intensive ultraviolet.It is different
In other plant, the anthocyanin monomer major part that purple sweetpotato contains all is to be acylated bioside anthocyanin, such anthocyanin activity
It is higher.The anthocyanin monomer extracted from purple sweetpotato is proven to have efficient antioxidation activity, and its oxidation resistance is better than dimension life
Plain C and vitamin E.At present, extract from anthocyanins pigment from purple sweet potato monomer and be used for food, function more as a kind of novel antioxidant
Sex-health products industry, in not using it for anti-oxidant class skin care item formula also.Meanwhile, before high-efficiency antioxidant effect is ensured
Put, improve and use comfort and stability, especially using gel-type vehicle, lubricate non-greasy, low irritant.
The content of the invention
The purpose of the present invention is providing a kind of composite skin care product, and said composition is mainly by the raw material group of following weight portion
Into：15~20 parts of anthocyanin monomer, 3~5 parts of glycerine, 2.5~5 parts of butanediol, 1~2 part of beta glucan, carrageenan sodium 0.3
~2 parts, 2~4 parts of Matrixyl -5,0.3~1 part of hyaluronic acid, 0.9~1.5 part of dipotassium glycyrrhizinate, glutathione 3~5
50~70 parts of part, 0.5~1 part of triethanolamine, 3~4 parts of 1,2- pentanediols and deionized water.
Composite skin care product of the invention or gel, wherein anthocyanin monomer be 3-O- 6-O- (E)-caffeoyl -2-O- β -
D- glycopyranosyl-β-D- glucopyranosides } -5-O- β-D- glucoside Cyanidins, its chemical structural formula such as following formula,
The composite skin care product of the invention described above, further includes 0.3~2 part of the Carbomer of weight portion.
Preferably, composite skin care product of the invention, is mainly made up of the raw material of following weight portion：Anthocyanin monomer 17
Part, 4 parts of glycerine, 3 parts of butanediol, 1 part of beta glucan, 1 part of carrageenan sodium, 2 parts of Matrixyl -5,1 part of hyaluronic acid,
1 part of dipotassium glycyrrhizinate, 4 parts of glutathione, 1 part of Carbomer, 0.8 part of triethanolamine, 4 parts of 1,2- pentanediols and deionized water 60.2
Part.
The preferred composite skin care product of the invention described above, further includes 1 part of the Carbomer of weight portion.
The composite skin care product of the invention described above, the composition is gel, emulsion or creme etc., preferably gel
Agent.
On the other hand, it is an object of the invention to provide a kind of skin care item gel, it is made up of the raw material of following weight portion：Flower
15~20 parts of color glycosides monomer, 3~5 parts of glycerine, 2.5~5 parts of butanediol, 1~2 part of beta glucan, 0.3~2 part of carrageenan sodium,
2~4 parts of Matrixyl -5,0.3~1 part of hyaluronic acid, 0.9~1.5 part of dipotassium glycyrrhizinate, 3~5 parts of glutathione, card ripple
50~70 parts of 0.3~2 part of nurse, 0.5~1 part of triethanolamine, 3~4 parts of 1,2- pentanediols and deionized water.
In one embodiment, skin care item gel of the present invention, is made up of the raw material of following weight portion：Pattern
It is 17 parts of glycosides monomer, 4 parts of glycerine, 3 parts of butanediol, 1 part of beta glucan, 1 part of carrageenan sodium, 2 parts of Matrixyl -5, transparent
1 part of matter acid, 1 part of dipotassium glycyrrhizinate, 4 parts of glutathione, 1 part of Carbomer, 0.8 part of triethanolamine, 4 parts of 1,2- pentanediols and go from
60.2 parts of sub- water.
Present invention also offers a kind of method for preparing composite skin care product, comprise the following steps：
(1) under high velocity agitation, Carbomer, carrageenan sodium powder end are slowly spread in a certain amount of deionized water, fully
Stirring is until Carbomer, carrageenan sodium are completely dispersed and are swelled into solution；
(2) solution of heating stepses (1) is to 80 DEG C, and continues high-speed stirred 15 minutes, then stands and is cooled to room temperature, delays
Slow addition triethanolamine, it is stirring while adding, obtain transparence gel-type vehicle；
(3) glycerine is measured, butanediol, beta glucan, 1,2- pentanediols is added, solution is stirred into, then in stirring
It is lower that solution is added into the matrix of step (2), form solution；
(4) by remaining deionized water and Matrixyl -5, hyaluronic acid, dipotassium glycyrrhizinate, glutathione, anthocyanin
Monomer is well mixed, and obtains solution；
(5) under agitation, the solution of step (4) is added in the solution of step (3), stir can be prepared by containing
The gel of anthocyanin monomer.
In another embodiment, a kind of method for preparing skin care item gel of the invention, comprises the following steps：
(1) under high velocity agitation, 1g Carbomers, 1g carrageenans sodium powder end are slowly spread in 40g deionized waters, fully
Stirring is until Carbomer, carrageenan sodium are completely dispersed and are swelled into solution；
(2) solution of heating stepses (1) is to 80 DEG C, and continues high-speed stirred 15 minutes, then stands and is cooled to room temperature, delays
Slow addition 0.8g triethanolamines, it is stirring while adding, obtain transparence gel-type vehicle；
(3) 4g glycerine is measured, adds 3g butanediols, 1g beta glucans, 4g 1,2- pentanediols to stir, then stirring
Mix it is lower will step (3) solution add step (2) matrix in form solution；
(4) by remaining 20.2g deionized waters and 2g Matrixyls -5,1g hyaluronic acids, 1g dipotassium glycyrrhizinates, 4g paddy
The sweet peptide of Guang, 17g anthocyanin monomers are well mixed, and obtain solution；
(5) solution of step (4) is added in the solution of step (3) under agitation, stir can be prepared by containing
The gel of anthocyanin monomer.
In the method for preparing gel of the invention described above, the weight of raw material also is understood as weight portion.
Composite skin care product of the invention, particularly skin care item gel contains anthocyanin monomer, makes the change such as face cream, gel
Cosmetic has functions that to improve skin ageing, improves wrinkle and color spot.Composite skin care product of the invention or gel with can
Anthocyanin monomer stabilization, long-term storage is set to be conducive to keeping effect, vitamin C E is better than to the improvement ability of skin ageing and is combined
Essence, and be considerably less than using the number of vitamin C E composite essence liquids without the number for improving, and relaxed with good
Suitable sense, smearing sense.
Specific embodiment
Following examples are used for the essence that the present invention is furture elucidated, the scope of but do not limit the invention in any way.
Skin care item gel of the embodiment 1 containing anthocyanin monomer and its preparation
The formula of skin care item gel：
Anthocyanin monomer 17g, glycerine 4g, butanediol 3g, beta glucan 1g, carrageenan sodium 1g, Matrixyl -5
2g, hyaluronic acid 1g, dipotassium glycyrrhizinate 1g, glutathione 4g, Carbomer 1g, triethanolamine 0.8g, 1,2- pentanediols 4g and go
Ionized water 60.2g.
(1) under high velocity agitation, 1g Carbomers, 1g carrageenans sodium powder end are slowly spread in 40g deionized waters, fully
Stirring until Carbomer, carrageenan sodium be completely dispersed it is swelling.
(2) heating (1) solution is to 80 DEG C, and continues high-speed stirred 15 minutes, then stands and is cooled to room temperature, is slowly added to
0.8g triethanolamines, it is stirring while adding, obtain transparence gel-type vehicle.
(3) 4g glycerine is measured, adds 3g butanediols, 1g beta glucans, 4g 1,2- pentanediols to be stirred into solution, side
Be added to solution in the solution of (2) by stirring at low speed side, forms solution.
(4) by remaining 20.2g deionized waters and 2g Matrixyls -5,1g hyaluronic acids, 1g dipotassium glycyrrhizinates, 4g paddy
The sweet peptide of Guang, 17g anthocyanin monomers are well mixed, and obtain solution.
(5) stir in the solution of solution addition (3) of (4) and can be prepared by containing anthocyanin in stirring at low speed
The gel of monomer.
Skin care item gel of the embodiment 2 containing anthocyanin monomer and its preparation
The formula of skin care item gel：Anthocyanin monomer 15g, glycerine 3g, butanediol 2.5g, beta glucan 2g, carrageenan
Sodium 0.3g, the 3g of Matrixyl -5, hyaluronic acid 0.3g, dipotassium glycyrrhizinate 0.9g, glutathione 3g, Carbomer 0.3g, three second
Hydramine 0.5g, 1,2- pentanediols 3g and deionized water 66.2g.
Preparation technology is such as the method for embodiment 1.
Skin care item gel of the embodiment 3 containing anthocyanin monomer and its preparation
The formula of skin care item gel：Anthocyanin monomer 20g, glycerine 5g, butanediol 5g, beta glucan 1g, carrageenan sodium
2g, the 4g of Matrixyl -5, hyaluronic acid 0.5g, dipotassium glycyrrhizinate 1.5g, glutathione 5g, Carbomer 2g, triethanolamine
1g, 1,2- pentanediols 4g and deionized water 50g.
Preparation technology is such as the method for embodiment 1.
Clinical efficacy：
In June, -2016 in January, 2016, gel to the present invention containing anthocyanins pigment from purple sweet potato monomer be (such as embodiment 1
Formula gel) clinical observation on the therapeutic effect has been carried out, assessing the gel skin care item containing anthocyanins pigment from purple sweet potato monomer improves skin ageing
Effect.Take digital mark method that patient is randomly divided into two groups, wherein control group 40, wherein male 9, women 31,
27~41 years old age, average 27.9 years old；Treatment group 40, male 7, women 33,26~40 years old age, average 28.3 years old.
Primary skin problem has light line, wrinkle.
1. treatment method：Control group sooner or later respectively once, is continuously used using the commercially available Essence being combined containing vitamin C E
2 months.The skin care item gel containing anthocyanins pigment from purple sweet potato monomer that treatment group is prepared with the present invention, sooner or later respectively once, continuously makes
With 2 months.
2. evaluation criteria：Before treatment, treatment 2 months after shoot standardization picture, the light line of comparative evaluation, wrinkle.4 grades of improvement
(improving 76%-100%), 3 grades of improvement (improving 51%-75%), 2 grades improve (improve 26%-50%), and 1 grade improves (improvement
1%-25%), without improvement；(total to improve+4 grades of improvement rates of effective percentage=1 grade of+2 grades of improvement rate+3 grades of improvement rate improvement rate).
3. assessment result：Light line, wrinkle improve efficient comparing result and see the table below 1.
The light line of table 1, wrinkle improve efficient comparing result
4. the result explanation of table 1：Gel containing anthocyanins pigment from purple sweet potato monomer is better than dimension to the improvement ability of skin ageing
Raw element CE composite essence liquids, and the number for using vitamin C E composite essence liquids is considerably less than without the number for improving.
In January, -2017 in July, 2016, internal control is carried out to gel of the present invention containing anthocyanins pigment from purple sweet potato monomer clinical
Observation of curative effect, assessing the gel skin care item containing anthocyanins pigment from purple sweet potato monomer improves color spot, pigmented ability.Take numeral
Patient is randomly divided into two groups by mark method, wherein control group 50, women 37, male 13, age 25-40 Sui, averagely
29.0 years old, the course of disease 2 months~5 years, average 2 years；Treatment group 56, women 41, male 15,24~39 years old age, averagely
28.2 years old, the course of disease 3 months~6 years, average 2 years.Primary disease has the chromatodermatosis such as chloasma, freckle.
1. clinical manifestation and symptom：Women is more compared with male, is apt to occur in face, shows as Facial symmetry, meshy arrangement color
Plain calmness patch.
2. treatment method：Control group uses the commercially available Essence containing L-vitamin C, sooner or later respectively once, continuously uses 2
Individual month.The gel containing anthocyanins pigment from purple sweet potato monomer that treatment group is prepared with the present invention, sooner or later respectively once,
It is continuous to use 2 months.
3. criterion of therapeutical effect：After 2 months, situation is mitigated to color spot and is evaluated.
A is almost recovered：Color spot area regression >=90%, color disappears substantially
B is effective：Color spot area regression 60%~89%, color is substantially thin out
C takes a turn for the better：Color spot area regression 30%~59%, color is thin out
D is invalid：Color spot area disappears<30%, color change is not obvious
(rate that is almost recovered plus obvious effective rate plus improvement rate, add up to total effective rate)
4. color spot improvement assessment result is shown in Table 2.
The comparing result that the color spot of table 2 improves
5. the result explanation of table 2：Gel containing anthocyanins pigment from purple sweet potato monomer improves color spot, pigmented ability and is better than
Contain ascorbic Essence.
Gel containing anthocyanins pigment from purple sweet potato monomer prepared by the present invention is tried for a long time with commercially available anti-oxidant Essence
With comparing, the evaluation test of skin sense is carried out, test number is 30 people, and test result is as shown in table 3 below：
The long-term use comfort of table 3 and smearing sense comparing result
The result explanation of table 3：Gel totality skin sense score of the present invention containing anthocyanins pigment from purple sweet potato monomer is anti-better than commercially available
Oxidation Essence, especially in terms of comfort, smearing impression is used.
Stability test
Study on the stability experiment is carried out to gel prepared by embodiment 1, embodiment 2, embodiment 3, test result is as follows：
The study on the stability result of table 4
The result of table 4 shows：Composition or gel containing anthocyanins pigment from purple sweet potato monomer of the invention can very well keep pattern
Glycosides monomer stabilization, anthocyanin monomer will not be separated out, while in the case of low temperature, room temperature, high temperature and illumination, gel does not occur bright
Aobvious discoloration problem.With the method testing example 1 of efficient liquid phase, embodiment 2, embodiment 3 under different storage conditions pattern
The content of glycosides monomer, the degraded of anthocyanin monomer can be ignored, and the gel containing anthocyanin monomer has excellent stabilization
Property, the demand of listing can be met.Gel stable for extended periods of time of the invention, effect remains permanent.
Claims (10)
1. a kind of composite skin care product, is mainly made up of the raw material of following weight portion：15~20 parts of anthocyanin monomer, glycerine 3~5
Part, 2.5~5 parts of butanediol, 1~2 part of beta glucan, 0.3~2 part of carrageenan sodium, Matrixyl -52~4 part, hyalomitome
Sour 0.3~1 part, 0.9~1.5 part of dipotassium glycyrrhizinate, 3~5 parts of glutathione, 0.5~1 part of triethanolamine, 1,2- pentanediols 3~
4 parts and 50~70 parts of deionized water.
2. composite skin care product as claimed in claim 1, is mainly made up of the raw material of following weight portion：Anthocyanin monomer 17
It is part, 4 parts of glycerine, 3 parts of butanediol, 1 part of beta glucan, 1 part of carrageenan sodium, -52 parts of Matrixyl, 1 part of hyaluronic acid, sweet
1 part of oxalic acid dipotassium, 4 parts of glutathione, 1 part of Carbomer, 0.8 part of triethanolamine, 4 parts of 1,2- pentanediols and deionized water 60.2
Part.
3. composite skin care product as claimed in claim 1, it is characterised in that：Further include the Carbomer 0.3~2 of weight portion
Part.
4. composite skin care product as claimed in claim 2, it is characterised in that：Further include 1 part of the Carbomer of weight portion.
5. composite skin care product as claimed in claim 1 or 2, it is characterised in that：The composition is gel, creme or breast
Agent.
6. composite skin care product as claimed in claim 5, it is characterised in that：The composition is gel.
7. a kind of method of the composite skin care product for preparing claim 1, comprises the following steps：
(1) under high velocity agitation, Carbomer, carrageenan sodium powder end are slowly spread in deionized water, are sufficiently stirred for until card
Ripple nurse, carrageenan sodium are completely dispersed and are swelled into solution；
(2) solution of heating stepses (1) is to 80 DEG C, and continues high-speed stirred 15 minutes, then stands and is cooled to room temperature, adds three
Monoethanolamine, it is stirring while adding, obtain transparence gel-type vehicle；
(3) glycerine is measured, butanediol, beta glucan, 1,2- pentanediols is added, solution is stirred into, then under agitation will
Solution is obtained in the matrix of solution addition step (2)；
(4) by remaining deionized water and Matrixyl -5, hyaluronic acid, dipotassium glycyrrhizinate, glutathione, anthocyanin monomer
It is well mixed, obtain solution；
(5) under agitation, the solution of step (4) is added in the solution of step (3), stirs and can be prepared by containing pattern
The gel of glycosides monomer.
8. a kind of skin care item gel, is made up of the raw material of following weight portion：15~20 parts of anthocyanin monomer, 3~5 parts of glycerine, fourth
2.5~5 parts of glycol, 1~2 part of beta glucan, 0.3~2 part of carrageenan sodium, Matrixyl -52~4 part, hyaluronic acid 0.3
~1 part, 0.9~1.5 part of dipotassium glycyrrhizinate, 3~5 parts of glutathione, 0.3~2 part of Carbomer, 0.5~1 part of triethanolamine, 1,
50~70 parts of 3~4 parts of 2- pentanediols and deionized water.
9. gel as claimed in claim 8, is made up of the raw material of following weight portion：17 parts of anthocyanin monomer, 4 parts of glycerine, fourth
3 parts of glycol, 1 part of beta glucan, 1 part of carrageenan sodium, -52 parts of Matrixyl, 1 part of hyaluronic acid, 1 part of dipotassium glycyrrhizinate,
60.2 parts of 4 parts of glutathione, 1 part of Carbomer, 0.8 part of triethanolamine, 4 parts of 1,2- pentanediols and deionized water.
10. a kind of method for preparing skin care item gel, comprises the following steps：
(1) under high velocity agitation, 1g Carbomers, 1g carrageenans sodium powder end are slowly spread in 40g deionized waters, are sufficiently stirred for
Until Carbomer, carrageenan sodium are completely dispersed and are swelled into solution；
(2) solution of heating stepses (1) is to 80 DEG C, and continues high-speed stirred 15 minutes, then stands and is cooled to room temperature, slow to add
Enter 0.8g triethanolamines, it is stirring while adding, obtain transparence gel-type vehicle；
(3) 4g glycerine is measured, adds 3g butanediols, 1g beta glucans, 4g 1,2- pentanediols to stir, then under agitation
The solution of step (3) is added in the matrix of step (2) and forms solution；
(4) by remaining 20.2g deionized waters and 2g Matrixyls -5,1g hyaluronic acids, 1g dipotassium glycyrrhizinates, 4g gluathiones
Peptide, 17g anthocyanin monomers are well mixed, and obtain solution；
(5) solution of step (4) is added in the solution of step (3) under agitation, stirs and can be prepared by containing pattern
The gel of glycosides monomer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710240672.3A CN106860054A (en) | 2017-04-13 | 2017-04-13 | Composite skin care product and preparation method thereof, skin care item gel and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710240672.3A CN106860054A (en) | 2017-04-13 | 2017-04-13 | Composite skin care product and preparation method thereof, skin care item gel and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107468539A (en) * | 2017-08-14 | 2017-12-15 | 北京明弘科贸有限责任公司 | One kind contains ascorbic sub- gel and preparation method and application |
| CN110698699A (en) * | 2019-10-28 | 2020-01-17 | 天津一安生物技术有限公司 | Method for preparing sodium hyaluronate gel by puerarin crosslinking and sodium hyaluronate gel |
| CN112386506A (en) * | 2019-08-16 | 2021-02-23 | 上海可米日化股份有限公司 | Skin care gel containing peptide-alcohol liposome compound and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961276A (en) * | 2014-01-08 | 2014-08-06 | 片仔癀（上海）生物科技研发有限公司 | Anti-glycation cosmetic composition and anti-glycation cosmetics containing same |
| CN104926777A (en) * | 2014-12-12 | 2015-09-23 | 中国科学院成都生物研究所 | Preparation technology of high-content purple potato anthocyanin extract |
| CN105411926A (en) * | 2015-12-03 | 2016-03-23 | 青蛙王子(中国)日化有限公司 | Skin-tendering essence rich in anthocyanin and preparation method of skin-tendering essence |
-
2017
- 2017-04-13 CN CN201710240672.3A patent/CN106860054A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961276A (en) * | 2014-01-08 | 2014-08-06 | 片仔癀（上海）生物科技研发有限公司 | Anti-glycation cosmetic composition and anti-glycation cosmetics containing same |
| CN104926777A (en) * | 2014-12-12 | 2015-09-23 | 中国科学院成都生物研究所 | Preparation technology of high-content purple potato anthocyanin extract |
| CN105411926A (en) * | 2015-12-03 | 2016-03-23 | 青蛙王子(中国)日化有限公司 | Skin-tendering essence rich in anthocyanin and preparation method of skin-tendering essence |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107468539A (en) * | 2017-08-14 | 2017-12-15 | 北京明弘科贸有限责任公司 | One kind contains ascorbic sub- gel and preparation method and application |
| CN112386506A (en) * | 2019-08-16 | 2021-02-23 | 上海可米日化股份有限公司 | Skin care gel containing peptide-alcohol liposome compound and preparation method thereof |
| CN110698699A (en) * | 2019-10-28 | 2020-01-17 | 天津一安生物技术有限公司 | Method for preparing sodium hyaluronate gel by puerarin crosslinking and sodium hyaluronate gel |
| CN110698699B (en) * | 2019-10-28 | 2022-03-11 | 天津一安生物技术有限公司 | Method for preparing sodium hyaluronate gel by puerarin crosslinking and sodium hyaluronate gel |
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Application publication date: 20170620 |