CN106834032A - The application of gout health care product or medicament is controlled in a kind of alcoholic drink mixed with fruit juice, preparation method and its preparation - Google Patents
The application of gout health care product or medicament is controlled in a kind of alcoholic drink mixed with fruit juice, preparation method and its preparation Download PDFInfo
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Abstract
The invention provides the application that gout health care product or medicament are controlled in a kind of alcoholic drink mixed with fruit juice, preparation method and its preparation.The component of alcoholic drink mixed with fruit juice of the present invention includes base liquor, caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root, is fitted to each other between above-mentioned traditional Chinese medicinal components, and compatibility is reasonable, there is the effect of Synergistic in terms of gout is treated, not only instant effect, good effect but also the recurrence rate of gout is reduced, meanwhile, the alcoholic drink mixed with fruit juice entrance is continuous, the mouth that falls is sweet, there is emblic after drink, long times of aftertaste, existing aroma has the fragrance of agalloch eaglewood and the fruity also fragranced with herbal medicine of balloonflower root again, fragrance level enriches, and patient is happy to drink.Meanwhile, the present invention prepares alcoholic drink mixed with fruit juice by way of caulis lonicerae, pseudo-ginseng etc. being immersed directly in base liquor or the extract solution of above-mentioned medicinal material is added into base liquor, the preparation method process is simple, easily operation, is adapted to large-scale production.
Description
Technical field
The present invention relates to alcoholic drink mixed with fruit juice field, gout health care product are controlled in particular to a kind of alcoholic drink mixed with fruit juice, preparation method and its preparation
Or the application of medicament.
Background technology
Gout, is also called " hyperuricemia ", be it is a kind of increase because biosynthesis of purine is metabolized, uric acid produce it is excessive or
Because uric acid excretion is bad cause blood in uric acid raise, urate crystal is deposited in synovium of joint, synovial bursa, cartilage and its hetero-organization
The repeated relapsing inflammatory disease for causing.Clinical symptoms is mainly shown as：Caused by hyperuricemia and urate crystal, deposition
Characteristic acute arthritis, tophus, interstitial nephritis, severe patient are shown in joint deformity and dysfunction, often with uric acid urinary tract
Calculus.For a long time, the incidence of disease of gout remains high always in mid-aged population, especially middle-aging male colony, gives
The body of patient causes major injury, psychologically also brings immense pressure, has a strong impact on patients ' life quality.
At present to the treatment of gout still based on Western medicine, conventional have colchicin, an allopurinol, foregoing medicine, mostly
Abirritant, it is difficult to effect a radical cure, and all with obvious toxic and side effect, such as upset,gastro-intestinal, severe patient can occur hemorrhagic enteritis,
Blood middle leukocytes are reduced, severe patient can cause aplastic anemia, alopecia, myopathy, hepatic disorder, depression etc..
And for the traditional Chinese medicine treatment of gout, there is Simiao Yongan Tang, and juanbi decoction, Traditional Chinese medicine decoction for treating-ache and expelling atagnate, clearing heat and promoting diuresis eliminating impediment side etc., belong to more
In Chinese medicine ancient prescription, though there is certain curative effect, Chinese medicines soup decoction process is complicated, works slow, and the course for the treatment of is long, and some patientss are treated
Effect is not obvious.
Prior art also has Chinese medicine the brewed acquisition medicinal liquor together with wine, for treating gout, on the one hand can reduce west
The side effect of medicine treatment, the opposing party can promote the dissolving of the active ingredient in medicinal material and the absorption of human body.But it is existing to control
All there are various defects in the medicinal liquor for treating gout：The medicinal liquor of major part treatment gout is present matches somebody with somebody reasonable, slowly effect, weak curative effect,
Therapeutic effect defect repeatedly；Although the medicinal liquor curative effect of part treatment gout is still, 20~30 kinds of Chinese medicines must be added, sometimes
The rare medicinal herbs such as tiger bone, pilose antler, ganoderma lucidum, ginseng must also be added, complexity is not only formulated, drug effect is difficult to control to, and cost mistake
High, preparation is difficult；In addition, the medicinal material for being used to treat gout in being added to medicinal liquor is worked hard highly seasoned mostly, medicinal liquor bitterness is difficult to entrance,
For patient does not like.
Therefore, this area urgently propose one kind treat gout instant effect, do not recur, have no toxic side effect, therapeutic effect it is good and
In good taste, formula is simple, medicinal liquor that is easily preparing.
In view of this, it is special to propose the present invention.
The content of the invention
The first object of the present invention is to provide a kind of alcoholic drink mixed with fruit juice, the alcoholic drink mixed with fruit juice when gout is treated instant effect, do not recur, treat
Imitate, and it is in good taste, patient is happy to drink.
The second object of the present invention is to provide a kind of preparation method of the alcoholic drink mixed with fruit juice, and the preparation method is simple and easy to apply,
Easily operation, is adapted to large-scale production.
The third object of the present invention is the application for providing above-mentioned alcoholic drink mixed with fruit juice in the health products or medicament for preparing treatment gout,
Health products or medicament prepared by the application can effectively treat gout, prevent gout from recurring.
In order to realize above-mentioned purpose of the invention, spy uses following technical scheme：
A kind of alcoholic drink mixed with fruit juice, the alcoholic drink mixed with fruit juice is made up of base liquor with auxiliary material, wherein auxiliary material include caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and
Balloonflower root.
The above-mentioned alcoholic drink mixed with fruit juice of the present invention in base liquor by after strict selection, adding traditional Chinese medicinal components caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, heavy
Fragrant and balloonflower root.
Wherein, caulis lonicerae, it is sweet, it is cold in nature, with dispelling wind and removing obstruction in the meridians, clearing heat and detoxicating, anti-inflammatory, antianaphylaxis, hypertension and hyperlipemia
Effect, be generally used for curing mainly the illnesss such as arthralgia pain due to rheumatism, heating redness, sore carbuncle swells, toxic-heat and blood stasis, warm disease heating.Caulis lonicerae
Rich in organic acid, volatile oil, flavones and saponins compound；Wherein, organic acid and Hederagenin -3-0-a-I just adjoin the Ah that mutters
There is anti-inflammatory, antipyretic, analgesic to act on to draw the saponins compounds such as primary glucosides；The flavone compound such as honeysuckle element and cyanidenon
Renal tubule can be blocked and absorb lithate, be allowed to accelerate excretion, preventing and treating lithate generation is played a part of in content dilution.
Pseudo-ginseng, also known as pseudo-ginseng, its is warm in nature, sweet and slightly bitter taste, with dispelling wind and eliminating dampness, the effect restored menstrual flow and invigorated blood circulation with swelling and pain relieving.
Contain arasaponin, various sugared parts and amino acid and the necessary trace element of human body in pseudo-ginseng；Wherein arasaponin energy
The release of inflammatory cytokine is effectively reduced, internal oxygen radical is removed, suppresses mast cell release histamine isoreactivity material,
With the effect for improving patient's immunologic derangement state and anti-inflammatory.
Radix Glycyrrhizae, flat property and sweet taste, rich in flavones ingredients such as glycyrrhizin, glycyrrhizic acid and glycyrrhizins, with anti-inflammatory, removing toxic substances,
Heat-clearing, purging intense heat, moistening lung etc. are acted on, and can be invigorated the spleen and benefited qi, relieving spasm to stop pain, anti-inflammation, for deficiency of spleen-QI and stomach-QI, lassitude hypodynamia, four limbs
Contraction urgency pain is evident in efficacy.
Agalloch eaglewood, taste fragrance is warm in nature auxiliary containing volatile oil, flavones and its glycoside, phenols, triterpenes, polysaccharide and amino acid
Sun, has functions that anti-inflammation, sedation-analgesia, clear god qi-regulating, promoting the circulation of qi cold dispelling, warm stomach temperature spleen.
Balloonflower root, taste it is micro- it is sweet after it is slightly bitter, slightly warm in nature enters lung channel, with eliminating the phlegm, sedation-analgesia, relievings asthma, anti-inflammatory, venting QI-blood, rushes down
Fiery cold dispelling and the effect of strengthen immunity.
Caulis lonicerae and pseudo-ginseng in the above-mentioned alcoholic drink mixed with fruit juice of the present invention are dispelling wind and eliminating dampness, clearing and activating the channels and collaterals and anti-inflammatory analgetic good merchantable brand, two
The compatibility of person has the effect of Synergistic.Compared with alone caulis lonicerae or pseudo-ginseng, in alcoholic drink mixed with fruit juice simultaneously add caulis lonicerae with
Pseudo-ginseng can significantly increase the effect that alcoholic drink mixed with fruit juice treats gout, the rapid content for reducing uric acid in patient's body, rapid recovery gout
Shape, and effectively reduce the recurrence rate of gout.And Radix Glycyrrhizae, agalloch eaglewood and balloonflower root have anti-inflammatory analgesic and the effect of calmness of calming the nerves, and bear
Winter rattan and pseudo-ginseng are used together, the effect with Synergistic, can further cooperate with enhancing alcoholic drink mixed with fruit juice to treat the effect of gout, together
When also enhance the effect of alcoholic drink mixed with fruit juice ataralgesia, reduce the pain of patient.
The Chinese medicine added in the above-mentioned alcoholic drink mixed with fruit juice of the present invention belongs to sweet, sweet or slight bitter type, and without adding, toil is highly seasoned
Chinese medicine, considerably reduce the bitter taste of general medicinal liquor, reduce conflict of the patient when drinking.Meanwhile, containing sweet in Radix Glycyrrhizae
Oxalic acid, sweet taste is 80~300 times of sucrose, is natural sweetener, and agalloch eaglewood has fragrant delicate fragrance, and sweet cool with sweet, balloonflower root taste is sweet
Slight bitter, with fruity delicate fragrance；Above-mentioned traditional Chinese medicinal components are added in alcoholic drink mixed with fruit juice can further lift the mouthfeel and fragrance of alcoholic drink mixed with fruit juice,
Make its entrance silk floss, the mouth that falls sweet, there is emblic after drink, long times of aftertaste, existing aroma has the fragrance of agalloch eaglewood and the fruity also band of balloonflower root again
There is the fragranced of herbal medicine, fragrance level enriches.
In some embodiments, the base liquor and auxiliary material weight are as follows：
50 parts of base liquor, 0.7~8 part of caulis lonicerae, 0.7~7 part of pseudo-ginseng, 0.7~7 part of Radix Glycyrrhizae, 0.7~7 part of agalloch eaglewood, balloonflower root
0.7~7 part；Or,
50 parts of base liquor, 1.5~7 parts of caulis lonicerae, 1~6 part of pseudo-ginseng, 1~6 part of Radix Glycyrrhizae, 1~6 part of agalloch eaglewood, 1~6 part of balloonflower root；
Or,
50 parts of base liquor, 3~6 parts of caulis lonicerae, 2~5 parts of pseudo-ginseng, 2~5 parts of Radix Glycyrrhizae, 2~5 parts of agalloch eaglewood, 2~5 parts of balloonflower root；Or
Person,
50 parts of base liquor, 4~5 parts of caulis lonicerae, 3~4 parts of pseudo-ginseng, 3~4 parts of Radix Glycyrrhizae, 3~4 parts of agalloch eaglewood, 3~4 parts of balloonflower root；Or
Person,
50 parts of base liquor, 6~8 parts of caulis lonicerae, 5~6 parts of pseudo-ginseng, 5~6 parts of Radix Glycyrrhizae, 5~6 parts of agalloch eaglewood, 5~6 parts of balloonflower root.
In order to strengthen caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root treat gout when synergistic function and take into account dew
The mouthfeel of wine, above-mentioned alcoholic drink mixed with fruit juice of the invention is further limited the content of each traditional Chinese medicinal components.In above-mentioned content range, honeysuckle
Rattan, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root can further cooperate with enhancing alcoholic drink mixed with fruit juice to treat the effect of gout, while also ensureing alcoholic drink mixed with fruit juice
Mouthfeel is sweet, mellow, and aroma is elegant long.
In some embodiments, the base liquor and auxiliary material weight are as follows：
50 parts of base liquor, 1.5 parts of caulis lonicerae, 1.2 parts of pseudo-ginseng, 1 part of Radix Glycyrrhizae, 0.9 part of agalloch eaglewood, 0.9 part of balloonflower root；Or,
50 parts of base liquor, 3 parts of caulis lonicerae, 2.5 parts of pseudo-ginseng, 2 parts of Radix Glycyrrhizae, 1.4 parts of agalloch eaglewood, 1.5 parts of balloonflower root；Or,
50 parts of base liquor, 4.5 parts of caulis lonicerae, 3.5 parts of pseudo-ginseng, 2.5 parts of Radix Glycyrrhizae, 2 parts of agalloch eaglewood, 2 parts of balloonflower root；Or,
50 parts of base liquor, 6 parts of caulis lonicerae, 5 parts of pseudo-ginseng, 4 parts of Radix Glycyrrhizae, 3.6 parts of agalloch eaglewood, 4 parts of balloonflower root；Or,
50 parts of base liquor, 7 parts of caulis lonicerae, 6 parts of pseudo-ginseng, 5 parts of Radix Glycyrrhizae, 4 parts of agalloch eaglewood, 4.2 parts of balloonflower root；Or,
50 parts of base liquor, 8 parts of caulis lonicerae, 7 parts of pseudo-ginseng, 6 parts of Radix Glycyrrhizae, 5 parts of agalloch eaglewood, 5.1 parts of balloonflower root.
The above-mentioned alcoholic drink mixed with fruit juice of the present invention has been carried out further preferably to the content of each component, in above-mentioned preferred technical scheme,
The curative effect and mouthfeel of alcoholic drink mixed with fruit juice are further strengthened.
In some embodiments, the auxiliary material also includes safflower, and the parts by weight of the safflower are 0.01~1.7 part,
Preferably 0.05 part.
Alcoholic drink mixed with fruit juice of the present invention preferably includes micro safflower, and the micro safflower has the effect of wind expelling stagnation removing, energy
Enough further enhance the effect that the alcoholic drink mixed with fruit juice treats gout.
In some embodiments, the base liquor be selected from white wine, yellow rice wine, fruit wine and beer in one or more, preferably
Ground, the base liquor is white wine.
In some embodiments, the white wine is selected from Maotai-flavor, delicate fragrance type, Luzhou-flavor, rice-fragrant type, strong fragrant odor type, phoenix
Odor type, sesame-flavor, odor type, fermented soya beans type, medicinal-flavor and Laobaigan-flavour, it is preferable that the white wine is Maotai-flavor.
In some embodiments, the number of degrees of the white wine are 33~68 degree, preferably 50~53 degree.
The above-mentioned alcoholic drink mixed with fruit juice of the present invention is carried out preferably to the species of base liquor, odor type and the number of degrees, wherein, the species of base liquor is preferably white
Wine, its alcohol content is high, it is possible to increase caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and in balloonflower root active ingredient dissolution, lifted alcoholic drink mixed with fruit juice
Effect.And odor type and Alcohol degree then particularly preferred 50~53 degree of Maotai-flavor liquor.Maotai-flavor liquor is rich in aromatic substance,
Taste elegant and delicate, wine body is mellow, enriches, long times of aftertaste, and hydrone and alcohol molecule forms in 50~53 degree of Maotai-flavor liquors
It is right preferably, taste most alcohol and.Therefore, the base liquor in alcoholic drink mixed with fruit juice is preferably 50~53 degree of Maotai-flavor liquor, can significantly carry
Rise the mouthfeel of alcoholic drink mixed with fruit juice.
The invention further relates to the preparation method of above-mentioned alcoholic drink mixed with fruit juice, methods described includes the step of mixing base liquor with auxiliary material.
In some embodiments, the step of mixing includes being immersed in auxiliary material in base liquor, it is preferable that immersion 6 days
More than, particularly preferably, soak more than 2 months；Or, the step of the mixing including the extract solution that will be extracted from auxiliary material with
The step of base liquor is blent.
The above-mentioned alcoholic drink mixed with fruit juice preparation method of the present invention is mixed traditional Chinese medicinal components with base liquor by way of soaking or blending, preparation side
Method is simple and easy to apply, is adapted to large-scale production.
The invention further relates to application of the above-mentioned alcoholic drink mixed with fruit juice in the health products or medicament for preparing treatment gout.
Compared with prior art, beneficial effects of the present invention are：
1), the present invention adds traditional Chinese medicinal components caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root, above-mentioned traditional Chinese medicinal components in alcoholic drink mixed with fruit juice
Compatibility rationally, with synergistic function so that the alcoholic drink mixed with fruit juice have treatment gout and ataralgesia effect, can quickly reduce
Uric acid content in patient's body, the pain of rapid reduction of patient, good effect, and conditions of patients are difficult repeatedly, hardly possible recurrence.
2), the traditional Chinese medicinal components of alcoholic drink mixed with fruit juice selection of the present invention belong to sweet, sweet or slight bitter type, without addition toil
Highly seasoned traditional Chinese medicinal components, reduce the Chinese medicine bitter taste of alcoholic drink mixed with fruit juice, make the more preferable entrance of alcoholic drink mixed with fruit juice；While Radix Glycyrrhizae, agalloch eaglewood and balloonflower root institute band
Sweet taste, fragranced and fruit flavor can further assign the sweet mellow mouthfeel of alcoholic drink mixed with fruit juice and the abundant fragrance of stereovision.
3), alcoholic drink mixed with fruit juice of the present invention further limits the proportioning of caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root, and to proportioning
Optimize, the synergistic function between enhancing each component makes the drug effect of alcoholic drink mixed with fruit juice more prominent, and mouthfeel more alcohol is just.
4) present invention also provides the preparation method of alcoholic drink mixed with fruit juice, and the method is immersed in base liquor by by medicinal material, or by medicinal material
Extract solution with base liquor blend being prepared from, the preparation method process is simple, easily operation, is adapted to large-scale production.
Specific embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the present invention.It is unreceipted specific in embodiment
Condition person, the condition advised according to normal condition or manufacturer is carried out.Agents useful for same or the unreceipted production firm person of instrument, are
The conventional products that can be obtained by commercially available purchase.
Embodiment 1
Weigh 53 degree of 50 kilograms of Maotai-flavor liquors, 1.5 kilograms of caulis lonicerae, 1.2 kilograms of pseudo-ginseng, 1 kilogram of Radix Glycyrrhizae, agalloch eaglewood 0.9
Kilogram and 0.9 kilogram of balloonflower root；Caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root are crushed, is mixed after crossing 90 mesh sieves；By mixture plus
Enter in 53 degree of Maotai-flavor liquors, sealing at normal temperatures is soaked 2 months；The cleaning dregs of a decoction, precipitation filtering obtains final product the alcoholic drink mixed with fruit juice for the treatment of gout.
Embodiment 2
Weigh 53 degree of 50 kilograms of Maotai-flavor liquors, 3 kilograms of caulis lonicerae, 2.5 kilograms of pseudo-ginseng, 2 kilograms of Radix Glycyrrhizae, agalloch eaglewood 1.4 thousand
Gram and 1.5 kilograms of balloonflower root；Caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root are crushed, is mixed after crossing 90 mesh sieves；Feed the mixture into
In 53 degree of Maotai-flavor liquors, sealing immersion at normal temperatures 2 months；The cleaning dregs of a decoction, precipitation filtering obtains final product the alcoholic drink mixed with fruit juice for the treatment of gout.
Embodiment 3
Weigh 53 degree of 50 kilograms of Maotai-flavor liquors, 4.5 kilograms of caulis lonicerae, 3.5 kilograms of pseudo-ginseng, 2.5 kilograms of Radix Glycyrrhizae, agalloch eaglewood 2
Kilogram and 2 kilograms of balloonflower root；Caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root are crushed, is mixed after crossing 90 mesh sieves；Feed the mixture into
In 53 degree of Maotai-flavor liquors, sealing immersion at normal temperatures 2 months；The cleaning dregs of a decoction, precipitation filtering obtains final product the alcoholic drink mixed with fruit juice for the treatment of gout.
Embodiment 4
Weigh 53 degree of 50 kilograms of Maotai-flavor liquors, 6 kilograms of caulis lonicerae, 5 kilograms of pseudo-ginseng, 4 kilograms of Radix Glycyrrhizae, 3.6 kilograms of agalloch eaglewood
With 4 kilograms of balloonflower root；Caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root are crushed, is mixed after crossing 90 mesh sieves；Feed the mixture into 53 degree
In Maotai-flavor liquor, sealing immersion at normal temperatures 2 months；The cleaning dregs of a decoction, precipitation filtering obtains final product the alcoholic drink mixed with fruit juice for the treatment of gout.
Embodiment 5
Weigh 53 degree of 50 kilograms of Maotai-flavor liquors, 7 kilograms of caulis lonicerae, 6 kilograms of pseudo-ginseng, 5 kilograms of Radix Glycyrrhizae, 4 kilograms of agalloch eaglewood and
4.2 kilograms of balloonflower root；Caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root are crushed, is mixed after crossing 90 mesh sieves；Feed the mixture into 53 degree
In Maotai-flavor liquor, sealing immersion at normal temperatures 2 months；The cleaning dregs of a decoction, precipitation filtering obtains final product the alcoholic drink mixed with fruit juice for the treatment of gout.
Embodiment 6
Weigh 53 degree of 50 kilograms of Maotai-flavor liquors, 7 kilograms of caulis lonicerae, 6 kilograms of pseudo-ginseng, 6 kilograms of Radix Glycyrrhizae, 5 kilograms of agalloch eaglewood and
5.1 kilograms of balloonflower root；Caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root are crushed, is mixed after crossing 90 mesh sieves；Feed the mixture into 53 degree
In Maotai-flavor liquor, sealing immersion at normal temperatures 2 months；The cleaning dregs of a decoction, precipitation filtering obtains final product the alcoholic drink mixed with fruit juice for the treatment of gout.
Embodiment 7
Weigh 38 degree of 50 kilograms of fen-flavor type white spirits, 6 kilograms of caulis lonicerae, 5 kilograms of pseudo-ginseng, 4 kilograms of Radix Glycyrrhizae, 3.6 kilograms of agalloch eaglewood
With 4 kilograms of balloonflower root；Caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root are crushed, is mixed after crossing 90 mesh sieves；Feed the mixture into 38 degree
In fen-flavor type white spirit, sealing immersion at normal temperatures 2 months；The cleaning dregs of a decoction, precipitation filtering obtains final product the alcoholic drink mixed with fruit juice for the treatment of gout.
Embodiment 8
Weigh 68 degree of 50 kilograms of aromatic Chinese spirits, 6 kilograms of caulis lonicerae, 5 kilograms of pseudo-ginseng, 4 kilograms of Radix Glycyrrhizae, 3.6 kilograms of agalloch eaglewood
With 4 kilograms of balloonflower root；Caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root are crushed, is mixed after crossing 90 mesh sieves；Feed the mixture into 68 degree
In aromatic Chinese spirit, sealing immersion at normal temperatures 2 months；The cleaning dregs of a decoction, precipitation filtering obtains final product the alcoholic drink mixed with fruit juice for the treatment of gout.
Comparative example 1
Weigh 53 degree of 50 kilograms of Maotai-flavor liquors, 4.5 kilograms of caulis lonicerae, 2.5 kilograms of Radix Glycyrrhizae, 2 kilograms of agalloch eaglewood and balloonflower root 2,000
Gram；Caulis lonicerae, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root are crushed, is mixed after crossing 90 mesh sieves；In feeding the mixture into 53 degree of Maotai-flavor liquors,
Sealing immersion at normal temperatures 2 months；The cleaning dregs of a decoction, precipitation filtering obtains final product the alcoholic drink mixed with fruit juice for the treatment of gout.
Comparative example 2
Weigh 53 degree of 50 kilograms of Maotai-flavor liquors, 3.5 kilograms of pseudo-ginseng, 2.5 kilograms of Radix Glycyrrhizae, 2 kilograms of agalloch eaglewood and balloonflower root 2,000
Gram；Pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and balloonflower root are crushed, is mixed after crossing 90 mesh sieves；In feeding the mixture into 53 degree of Maotai-flavor liquors,
Immersion 2 months is sealed under normal temperature；The cleaning dregs of a decoction, precipitation filtering obtains final product the alcoholic drink mixed with fruit juice for the treatment of gout.
Comparative example 3
Weigh 53 degree of 50 kilograms of Maotai-flavor liquors, 4.5 kilograms of caulis lonicerae, 3.5 kilograms of pseudo-ginseng；By caulis lonicerae and Radix Notoginseng powder
It is broken, mix after crossing 90 mesh sieves；Feed the mixture into 53 degree of Maotai-flavor liquors, sealing at normal temperatures is soaked 2 months；Cleaning medicine
Slag, precipitation filtering obtains final product the alcoholic drink mixed with fruit juice for the treatment of gout.
Experimental example 1
Evaluate therapeutic effect of the alcoholic drink mixed with fruit juice to chmice acute gouty arthritis：
Experiment male mouse of kunming is taken, body weight (25 ± 2) g, quantity 36 carries out chmice acute gouty arthritis and makes
Mould：Mouse carries out etherization in closed container, and mouse is observed at any time, prevents etherization excess, causes dead mouse.It is small
After mouse is anaesthetized, it is fixed in fixing device, selects the right side lower limb of mouse, the absorbent cotton soaked with the tincture of iodine and alcohol mixeding liquid
Toes portion of flower partly sterilised, draws 0.05mL uric acid sodium solution subplantar injections on the right side of metapedes, while in dorsal portion with syringe
Also hypodermic injection 0.05mL uric acid sodium solution at the 0.5cm of top, observes the metapedes obvious tumefaction of mouse, thicker, do not have blood and
Uric acid sodium solution overflows, then is put into cage tool after being disinfected to toes portion, prevents mouse from biting each other.After modeling, mouse is right
There is obvious tumefaction compared with left limb in metapedes toe, and no liquid is overflowed, and liquid is not fully absorbed, and points out acute gouty arthritis
Modeling success.
After modeling terminates, the mouse that will suffer from experimental study is randomly divided into 12 groups, every group 3, respectively negative right
According to, experimental group 1~8 and contrast groups 1~3, the alcoholic drink mixed with fruit juice for being prepared with 53 degree of Maotai-flavor liquors, embodiment 1~8 respectively and comparative example
1~3 alcoholic drink mixed with fruit juice feeding mouse for preparing, daily feeding 2 times, each 0.1g, continuous feeding 5 days detects that the inflammation of mouse refers to daily
Number.The classification of inflammatory index includes 0 grade, 1 grade, 2 grades, 3 grades, 4 grades altogether, wherein 0 grade represents toes portion normally, it is anti-without any inflammation
Should；1 grade represents that erythema occur in mild swelling, articular skin, and bone mark is high-visible, inflammatory reaction lesser extent；2 grades of joints
The swelling of position limitation, redness, bone mark is can't see, inflammatory reaction degree is heavier；3 grades of portions represented beyond toes portion joint
There is swelling in position, and inflammatory reaction degree is serious, foot heavy burden reduced capability, often lifts injury rear side limbs.
Therapeutic action of the alcoholic drink mixed with fruit juice of table 1 to experimental study mouse
It can be seen from data shown in table 1, compared with negative control (being not added with the white wine of the traditional Chinese medicinal components such as caulis lonicerae), the present invention
The inflammatory reaction degree that can substantially reduce mouse on the 1st~3 day of alcoholic drink mixed with fruit juice prepared by embodiment 1~8 after drinking, the 4th
The effect of basic healing can even be reached within~5 days, it can be seen that, the alcoholic drink mixed with fruit juice prepared by the embodiment of the present invention 1~8 is in treatment gout
When instant effect, good effect can effectively treat gout.Knowable to comparing with comparative example 1~3, the institute of the embodiment of the present invention 1~8
Effect is significant of the alcoholic drink mixed with fruit juice of preparation when gout is treated is better than comparative example 1~3, shows caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae, agalloch eaglewood and tangerine
Stalk with the use of with significant synergistic function.
Experimental example 2
Evaluate therapeutic effect of the alcoholic drink mixed with fruit juice to patient with gout：
120 patient with gout are convened, 12 groups are randomly divided into, every group of 10 people, as negative control group, experimental group 1~8 and right
Than group 1~3, drink prepared by common 53 degree of Maotai-flavor liquors, the alcoholic drink mixed with fruit juice of the preparation of embodiment 1~8 and comparative example 1~3 respectively
Alcoholic drink mixed with fruit juice 1 month, is drunk 2 times daily, and 100 grams are drunk every time, and period inquired the treatment of patient every 10 days, after the course for the treatment of terminates
Half a year, count the recurrence of patient.Specific testing result is referring to table 2.
The patient with gout therapeutic effect of table 2 is assessed
"-" is represented：Get nowhere；"+" is represented：Slightly take a turn for the better；" ++ " represents：Take a turn for the better；" +++ " represents：It is clearly better；“+++
+ " represent be almost recovered.
It can be seen from data shown in table 2, compared with negative control and comparative example 1~3, the alcoholic drink mixed with fruit juice prepared by embodiment 1~8
When gout is treated, not only instant effect, cure rate are high, and can also significantly reduce the recurrence rate of gout, show caulis lonicerae, pseudo-ginseng,
Radix Glycyrrhizae, agalloch eaglewood and balloonflower root have the effect of Synergistic in terms of gout is treated.
Experimental example 3
5 tasters are convened, the mouthfeel of alcoholic drink mixed with fruit juice, color and luster and fragrance enter to embodiment 1~8 and prepared by comparative example 1~3
Row is evaluated, sensory evaluation scores canonical reference table 3, and Analyses Methods for Sensory Evaluation Results is referring to table 4.
The alcoholic drink mixed with fruit juice sensory evaluation scores standard of table 3
The sensory evaluation score of the embodiment 1~8 of table 4 and comparative example 1~4
It can be seen from comparing comparative example 4 and embodiment 1~8, the Analyses Methods for Sensory Evaluation Results according to table 4, caulis lonicerae, pseudo-ginseng, Radix Glycyrrhizae,
Agalloch eaglewood and balloonflower root can lift the mouthfeel and fragrance of alcoholic drink mixed with fruit juice, especially the addition of Radix Glycyrrhizae, agalloch eaglewood and balloonflower root, can make alcoholic drink mixed with fruit juice
Mouthfeel is more sweet long, and its fragrance more enriches the sense that has levels.
Finally it should be noted that：Various embodiments above is merely illustrative of the technical solution of the present invention, rather than its limitations；To the greatest extent
Pipe has been described in detail with reference to foregoing embodiments to the present invention, but it will be understood by those within the art that：Its
The technical scheme described in foregoing embodiments can still be modified, or to which part or all technical characteristic
Carry out equivalent；And these modifications or replacement, the essence of appropriate technical solution is departed from various embodiments of the present invention skill
The scope of art scheme.
Claims (10)
1. a kind of alcoholic drink mixed with fruit juice, it is characterised in that the alcoholic drink mixed with fruit juice is made up of base liquor with auxiliary material, wherein auxiliary material include caulis lonicerae, pseudo-ginseng, sweet
Grass, agalloch eaglewood and balloonflower root.
2. alcoholic drink mixed with fruit juice as claimed in claim 1, it is characterised in that the base liquor and auxiliary material weight are as follows：
50 parts of base liquor, 0.7~8 part of caulis lonicerae, 0.7~7 part of pseudo-ginseng, 0.7~7 part of Radix Glycyrrhizae, 0.7~7 part of agalloch eaglewood, balloonflower root 0.7~7
Part；Or,
50 parts of base liquor, 1.5~7 parts of caulis lonicerae, 1~6 part of pseudo-ginseng, 1~6 part of Radix Glycyrrhizae, 1~6 part of agalloch eaglewood, 1~6 part of balloonflower root；Or,
50 parts of base liquor, 3~6 parts of caulis lonicerae, 2~5 parts of pseudo-ginseng, 2~5 parts of Radix Glycyrrhizae, 2~5 parts of agalloch eaglewood, 2~5 parts of balloonflower root；Or,
50 parts of base liquor, 4~5 parts of caulis lonicerae, 3~4 parts of pseudo-ginseng, 3~4 parts of Radix Glycyrrhizae, 3~4 parts of agalloch eaglewood, 3~4 parts of balloonflower root；Or,
50 parts of base liquor, 6~8 parts of caulis lonicerae, 5~6 parts of pseudo-ginseng, 5~6 parts of Radix Glycyrrhizae, 5~6 parts of agalloch eaglewood, 5~6 parts of balloonflower root.
3. alcoholic drink mixed with fruit juice as claimed in claim 1, it is characterised in that the base liquor and auxiliary material weight are as follows：
50 parts of base liquor, 1.5 parts of caulis lonicerae, 1.2 parts of pseudo-ginseng, 1 part of Radix Glycyrrhizae, 0.9 part of agalloch eaglewood, 0.9 part of balloonflower root；Or,
50 parts of base liquor, 3 parts of caulis lonicerae, 2.5 parts of pseudo-ginseng, 2 parts of Radix Glycyrrhizae, 1.4 parts of agalloch eaglewood, 1.5 parts of balloonflower root；Or,
50 parts of base liquor, 4.5 parts of caulis lonicerae, 3.5 parts of pseudo-ginseng, 2.5 parts of Radix Glycyrrhizae, 2 parts of agalloch eaglewood, 2 parts of balloonflower root；Or,
50 parts of base liquor, 6 parts of caulis lonicerae, 5 parts of pseudo-ginseng, 4 parts of Radix Glycyrrhizae, 3.6 parts of agalloch eaglewood, 4 parts of balloonflower root；Or,
50 parts of base liquor, 7 parts of caulis lonicerae, 6 parts of pseudo-ginseng, 5 parts of Radix Glycyrrhizae, 4 parts of agalloch eaglewood, 4.2 parts of balloonflower root；Or,
50 parts of base liquor, 8 parts of caulis lonicerae, 7 parts of pseudo-ginseng, 6 parts of Radix Glycyrrhizae, 5 parts of agalloch eaglewood, 5.1 parts of balloonflower root.
4. alcoholic drink mixed with fruit juice as claimed in claim 1, it is characterised in that the auxiliary material also includes safflower, the parts by weight of the safflower
It is 0.01~17 part, preferably 0.05 part.
5. the alcoholic drink mixed with fruit juice as described in any one of Claims 1 to 4, it is characterised in that the base liquor be selected from white wine, yellow rice wine, fruit wine and
One or more in beer, it is preferable that the base liquor is white wine.
6. alcoholic drink mixed with fruit juice as claimed in claim 5, it is characterised in that the white wine is selected from Maotai-flavor, delicate fragrance type, Luzhou-flavor, meter Xiang
Type, strong fragrant odor type, medicine odor type, sesame-flavor, odor type, fermented soya beans type, medicinal-flavor and Laobaigan-flavour, it is preferable that the white wine
It is Maotai-flavor.
7. alcoholic drink mixed with fruit juice as claimed in claim 6, it is characterised in that the number of degrees of the white wine are 33~68 degree, preferably 50~53 degree.
8. the preparation method of alcoholic drink mixed with fruit juice described in any one of claim 1~7, it is characterised in that methods described include by base liquor with it is auxiliary
The step of material mixing.
9. preparation method as claimed in claim 8, it is characterised in that include for auxiliary material being immersed in base liquor the step of the mixing
In, it is preferable that immersion more than 6 days, particularly preferably, soak more than 2 months；Or, including the step of the mixing will be from auxiliary
The step of extract solution extracted in material is blent with base liquor.
10. application of the alcoholic drink mixed with fruit juice described in any one of claim 1~7 in the health products or medicament for preparing treatment gout.
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