CN106822739A - 一种药食同源预防和治疗老年痴呆的颗粒 - Google Patents
一种药食同源预防和治疗老年痴呆的颗粒 Download PDFInfo
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Abstract
本发明公开了一种药食同源预防和治疗老年痴呆的颗粒,其特征在于:所述药食同源预防和治疗老年痴呆的颗粒按照重量的配方如下:人参2.5‑4份、枸杞子2.5‑4份、益智2.5‑4份、黄精1.5‑2.5份、玛咖0.2‑0.8份、大枣0.05‑0.2份、甘草0.05‑0.2份。补肾健脑,补中益气,养血安神,用于预防和治疗轻中度老年痴呆症(阿尔茨海默病),症见健忘、心悸、少气懒言、表情淡漠、头晕、神疲乏力、失眠、舌质淡、脉虚无力等。
Description
技术领域
本发明涉及治疗老年痴呆的颗粒技术领域,尤其涉及一种药食同源预防和治疗老年痴呆的颗粒。
背景技术
目前,关于老年痴呆病因机理研究的学说很多,在诸多学说中,金属铝在脑组织中的积蓄能引起神经元的衰老而引发的老年痴呆病是其中之一。铝是自然界中含量最多的金属,但并不是人体必需的微量元索。铝在正常人脑组织中的含量很低。正常人脑的铝含量上限仅为4微克/克,而老年痴呆患者脑组织铝含量明显高于正常人,最高可达到107微克/克。人们与铝制品有着广泛地接触,铝可通过食物链和医药进入人体。在一般情况下,由于铝不会在体内积累,因而毒性较低。但在老年人及肾脏病人(如尿毒症患者)中,铝却能够蓄积,并产生神经毒性。因此,预防和消除铝在人体内的异常蓄积尤为重要。使用金属鳌合剂“去铁胺”排铝,已在动物实验中表现了显著的效果。德国学者也有进入临床实验的报道并提出使用铝鳌合剂排铝治疗老年痴呆的新策略。从化学角度分析,使用“去铁胺”排铝有其必然性。因为铁、铝同属硬酸系列,有共同的化学属性特征。临床使用“去铁胺”虽然能够排铝,缓解老年痴呆病的症状并减慢老年痴呆病的进程,但是“去铁胺”不能通过血脑屏障,限制了它的临床应用。另外,“去铁胺”是天然生物生长素,化学合成困难、价格昂贵,而且不经消化道吸收,口服无效。为此,我们提出一种药食同源预防和治疗老年痴呆的颗粒
发明内容
本发明的目的在于提供一种药食同源预防和治疗老年痴呆的颗粒,以解决上述背景技术中提出的问题。
为了实现上述目的,本发明采用了如下技术方案:
一种药食同源预防和治疗老年痴呆的颗粒,所述药食同源预防和治疗老年痴呆的颗粒按照重量的配方如下:人参2.5-4份、枸杞子2.5-4份、益智2.5-4份、黄精1.5-2.5份、玛咖0.2-0.8份、山药0.2-0.8份、龙眼肉0.1-0.4份、大枣0.05-0.2份、甘草0.05-0.2份。
优选的,所述人参、枸杞子、益智的重量比为:2.6-3.5:2.6-3.5:2.6-3.5。
优选的,所述人参、枸杞子、益智的重量比为1:1:1。
优选的,所述黄精、玛咖、山药、龙眼肉、大枣、甘草的重量比为1.8-2.3:0.3-0.6:0.3-0.6:0.2-0.3:0.08-0.15:0.08-0.15。
优选的,所述玛咖和山药的重量比为1:1。
优选的,所述药食同源预防和治疗老年痴呆的颗粒按照重量的配方如下:所述人参2.8-3.2份、枸杞子2.8-3.2份、益智2.8-3.5份、黄精1.8-2.2份、玛咖0.4-0.6份、山药0.4-0.6份、龙眼肉0.15-0.3份、大枣0.07-0.12份、甘草0.07-0.12份。
本发明还提供一种药食同源预防和治疗老年痴呆颗粒的制备方法,包括如下步骤:
S1、材料预备,选取人参、枸杞子、益智、黄精、玛咖、山药、龙眼肉、大枣、甘草等药材进行精选,精选后对人参和玛咖处理:
a、将人参和玛咖采用低温真空微波干燥机进行干燥,设置温度30-40℃,真空度为-0.08到-0.12兆帕,时间设置为25-40min;
b、使用超微粉碎机,粉碎时间为5-8min,且将原料粉碎成200-400目的超微粉;
S2、流浸膏制备,a、提取,将枸杞子、益智、黄精、山药、龙眼肉、大枣、甘草等药材加4-8倍水,利用减压微波加热提取二次,温度控制在50-70℃,第一次1.2-1.8小时,第二次0.8-1.2小时,合并煎液,采用离心加膜分离技术过滤;
b、浓缩,减压微波浓缩至相对密度为1.20~1.25,温度为55~60℃,得到流浸膏;
S3、混合制粒,将S1中制备好的超微粉加入流浸膏中混匀,且使用低温真空微波干燥的方式对颗粒进行烘干,烘干时间为3-8min,再利用微囊包合技术制成颗粒;
S4、包装,将S3中烘干后的颗粒利用包装盒进行包装。
优选的,所述超微粉碎机和低温真空微波设备均经过消毒后使用。
本发明提供的一种药食同源预防和治疗老年痴呆的颗粒,本发明以人参、枸杞子、益智、黄精、玛咖、山药、龙眼肉、大枣、甘草为主原料,保证了人体内所需营养物的补充,且能够增强抵抗力,补肾健脑,补中益气,养血安神,用于预防和治疗轻中度老年痴呆症(阿尔茨海默病),症见健忘、心悸、少气懒言、表情淡漠、头晕、神疲乏力、失眠、舌质淡、脉虚无力等,且制得的产品不含任何化学合成物质,纯天然、无任何副作用,能够满足现在生活的需求。
具体实施方式
为了使本发明的目的、技术方案及优点更加清楚明白,以下结合具体实施例,对本发明进行进一步详细说明。应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。
实施例1
一种药食同源预防和治疗老年痴呆的颗粒,所述药食同源预防和治疗老年痴呆的颗粒按照重量的配方如下:人参3份、枸杞子3份、益智3份、黄精2份、玛咖0.5份、山药0.5份、龙眼肉0.2份、大枣0.1份、甘草0.1份。
本发明还提供一种药食同源预防和治疗老年痴呆颗粒的制备方法,包括如下步骤:
S1、材料预备,选取人参、枸杞子、益智、黄精、玛咖、山药、龙眼肉、大枣、甘草等药材进行精选,精选后对人参和玛咖处理:
a、将人参和玛咖采用低温真空微波干燥机进行干燥,设置温度35℃,真空度为-0.08兆帕,时间设置为30min;
b、使用超微粉碎机,粉碎时间为6min,且将原料粉碎成300目的超微粉;
S2、流浸膏制备,a、提取,将枸杞子、益智、黄精、山药、龙眼肉、大枣、甘草等药材加5倍水,利用减压微波加热提取二次,温度控制在65℃,第一次1.5小时,第二次1小时,合并煎液,采用离心加膜分离技术过滤;
b、浓缩,减压微波浓缩至相对密度为1.22,温度为60℃,得到流浸膏;
S3、混合制粒,将S1中制备好的超微粉加入流浸膏中混匀,且使用低温真空微波干燥的方式对颗粒进行烘干,烘干时间为5min,再利用微囊包合技术制成颗粒;
S4、包装,将S3中烘干后的颗粒利用包装盒进行包装。
实施例2
一种药食同源预防和治疗老年痴呆的颗粒,所述药食同源预防和治疗老年痴呆的颗粒按照重量的配方如下:人参2.8份、枸杞子2.8份、益智2.8份、黄精1.8份、玛咖0.3份、山药0.3份、龙眼肉0.2份、大枣0.08份、甘草0.08份。
本发明还提供一种药食同源预防和治疗老年痴呆颗粒的制备方法,包括如下步骤:
S1、材料预备,选取人参、枸杞子、益智、黄精、玛咖、山药、龙眼肉、大枣、甘草等药材进行精选,精选后对人参和玛咖处理:
a、将人参和玛咖采用低温真空微波干燥机进行干燥,设置温度32℃,真空度为-0.09兆帕,时间设置为30min;
b、使用超微粉碎机,粉碎时间为6min,且将原料粉碎成250目的超微粉;
S2、流浸膏制备,a、提取,将枸杞子、益智、黄精、山药、龙眼肉、大枣、甘草等药材加6倍水,利用减压微波加热提取二次,温度控制在60℃,第一次1.4小时,第二次0.9小时,合并煎液,采用离心加膜分离技术过滤;
b、浓缩,减压微波浓缩至相对密度为1.22,温度为58℃,得到流浸膏;
S3、混合制粒,将S1中制备好的超微粉加入流浸膏中混匀,且使用低温真空微波干燥的方式对颗粒进行烘干,烘干时间为4min,再利用微囊包合技术制成颗粒;
S4、包装,将S3中烘干后的颗粒利用包装盒进行包装。
实施例3
一种药食同源预防和治疗老年痴呆的颗粒,所述药食同源预防和治疗老年痴呆的颗粒按照重量的配方如下:人参3.5份、枸杞子3.5份、益智3.5份、黄精2.2份、玛咖0.4份、山药0.4份、龙眼肉0.25份、大枣0.15份、甘草0.15份。
本发明还提供一种药食同源预防和治疗老年痴呆颗粒的制备方法,包括如下步骤:
S1、材料预备,选取人参、枸杞子、益智、黄精、玛咖、山药、龙眼肉、大枣、甘草等药材进行精选,精选后对人参和玛咖处理:
a、将人参和玛咖采用低温真空微波干燥机进行干燥,设置温度38℃,真空度为-0.11兆帕,时间设置为35min;
b、使用超微粉碎机,粉碎时间为7min,且将原料粉碎成200目的超微粉;
S2、流浸膏制备,a、提取,将枸杞子、益智、黄精、山药、龙眼肉、大枣、甘草等药材加6倍水,利用减压微波加热提取二次,温度控制在65℃,第一次1.6小时,第二次1.1小时,合并煎液,采用离心加膜分离技术过滤;
b、浓缩,减压微波浓缩至相对密度为1.24,温度为58℃,得到流浸膏;
S3、混合制粒,将S1中制备好的超微粉加入流浸膏中混匀,且使用低温真空微波干燥的方式对颗粒进行烘干,烘干时间为7min,再利用微囊包合技术制成颗粒;
S4、包装,将S3中烘干后的颗粒利用包装盒进行包装。
实施例4
一种药食同源预防和治疗老年痴呆的颗粒,所述药食同源预防和治疗老年痴呆的颗粒按照重量的配方如下:人参4份、枸杞子4份、益智4份、黄精2.5份、玛咖0.8份、山药0.8份、龙眼肉0.4份、大枣0.2份、甘草0.2份。
本发明还提供一种药食同源预防和治疗老年痴呆颗粒的制备方法,包括如下步骤:
S1、材料预备,选取人参、枸杞子、益智、黄精、玛咖、山药、龙眼肉、大枣、甘草等药材进行精选,精选后对人参和玛咖处理:
a、将人参和玛咖采用低温真空微波干燥机进行干燥,设置温度40℃,真空度为-0.12兆帕,时间设置为40min;
b、使用超微粉碎机,粉碎时间为8min,且将原料粉碎成400目的超微粉;
S2、流浸膏制备,a、提取,将枸杞子、益智、黄精、山药、龙眼肉、大枣、甘草等药材加8倍水,利用减压微波加热提取二次,温度控制在70℃,第一次1.8小时,第二次1.2小时,合并煎液,采用离心加膜分离技术过滤;
b、浓缩,减压微波浓缩至相对密度为1.25,温度为60℃,得到流浸膏;
S3、混合制粒,将S1中制备好的超微粉加入流浸膏中混匀,且使用低温真空微波干燥的方式对颗粒进行烘干,烘干时间为8min,再利用微囊包合技术制成颗粒;
S4、包装,将S3中烘干后的颗粒利用包装盒进行包装。
以上所述,仅为本发明较佳的具体实施方式,但本发明的保护范围并不局限于此,任何熟悉本技术领域的技术人员在本发明揭露的技术范围内,根据本发明的技术方案及其发明构思加以等同替换或改变,都应涵盖在本发明的保护范围之内。
Claims (8)
1.一种药食同源预防和治疗老年痴呆的颗粒,其特征在于:所述药食同源预防和治疗老年痴呆的颗粒按照重量的配方如下:人参2.5-4份、枸杞子2.5-4份、益智2.5-4份、黄精1.5-2.5份、玛咖0.2-0.8份、山药0.2-0.8份、龙眼肉0.1-0.4份、大枣0.05-0.2份、甘草0.05-0.2份。
2.根据权利要求1所述的一种药食同源预防和治疗老年痴呆的颗粒,其特征在于:所述人参、枸杞子、益智的重量比为:2.6-3.5:2.6-3.5:2.6-3.5。
3.根据权利要求2所述的一种药食同源预防和治疗老年痴呆的颗粒,其特征在于:所述人参、枸杞子、益智的重量比为1:1:1。
4.根据权利要求1所述的一种药食同源预防和治疗老年痴呆的颗粒,其特征在于:所述黄精、玛咖、山药、龙眼肉、大枣、甘草的重量比为1.8-2.3:0.3-0.6:0.3-0.6:0.2-0.3:0.08-0.15:0.08-0.15。
5.根据权利要求1或2所述的一种药食同源预防和治疗老年痴呆的颗粒,其特征在于:所述玛咖和山药的重量比为1:1。
6.根据权利要求1所述的一种药食同源预防和治疗老年痴呆的颗粒,其特征在于:所述药食同源预防和治疗老年痴呆的颗粒按照重量的配方如下:所述人参2.8-3.2份、枸杞子2.8-3.2份、益智2.8-3.5份、黄精1.8-2.2份、玛咖0.4-0.6份、山药0.4-0.6份、龙眼肉0.15-0.3份、大枣0.07-0.12份、甘草0.07-0.12份。
7.一种权利要求1所述的药食同源预防和治疗老年痴呆颗粒的制备方法,其特征在于,包括如下步骤:
S1、材料预备,选取人参、枸杞子、益智、黄精、玛咖、山药、龙眼肉、大枣、甘草等药材进行精选,精选后对人参和玛咖处理:
a、将人参和玛咖采用低温真空微波干燥机进行干燥,设置温度30-40℃,真空度为-0.08到-0.12兆帕,时间设置为25-40min;
b、使用超微粉碎机,粉碎时间为5-8min,且将原料粉碎成200-400目的超微粉;
S2、流浸膏制备,a、提取,将枸杞子、益智、黄精、山药、龙眼肉、大枣、甘草等药材加4-8倍水,利用减压微波加热提取二次,温度控制在50-70℃,第一次1.2-1.8小时,第二次0.8-1.2小时,合并煎液,采用离心加膜分离技术过滤;
b、浓缩,减压微波浓缩至相对密度为1.20~1.25,温度为55~60℃,得到流浸膏;
S3、混合制粒,将S1中制备好的超微粉加入流浸膏中混匀,且使用低温真空微波干燥的方式对颗粒进行烘干,烘干时间为3-8min,再利用微囊包合技术制成颗粒;
S4、包装,将S3中烘干后的颗粒利用包装盒进行包装。
8.根据权利要求7所述的药食同源预防和治疗老年痴呆颗粒的制备方法,其特征在于:所述超微粉碎机和低温真空微波设备均经过消毒后使用。
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