CN106821793A - A kind of gentle efficient multiple corpus mamillare suncream and preparation method thereof - Google Patents
A kind of gentle efficient multiple corpus mamillare suncream and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/066—Multiple emulsions, e.g. water-in-oil-in-water
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/496—Triazoles or their condensed derivatives, e.g. benzotriazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4966—Triazines or their condensed derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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Abstract
The invention particularly discloses a kind of gentle efficient multiple corpus mamillare suncream, colostrumi bodies is first made, then make the multiple corpus mamillare comprising colostrumi bodies.The beneficial effects of the invention are as follows：With reference to special " the two film three-phases " structure of the multiple emulsified bodies of W/O/W; the chemical sun that will have potential stimulus is added in most interior phase; on the one hand chemical sun is carried out into a certain degree of protection; solve the problems, such as its photostability; on the other hand the concentration of chemical sun and direct skin contact is reduced, excitant is reduced to a certain extent；Therefore, multiple corpus mamillare suncream product compares general substance emulsified body sunscreen product, can be gentleer, non-stimulated, while sun-proof result also can more preferably, with very big application prospect.
Description
Technical field
The invention belongs to cosmetic field, specially a kind of gentle efficiently multiple corpus mamillare suncream and its preparation side
Method.
Background technology
Multiple emulsified body is the complicated multiple emulsification system comprising another more droplet again in dispersed phase drop.At present
It is dual structure corpus mamillare that research is more, i.e. W/O/W types or O/W/O type corpus mamillares.W/o type corpus mamillare is scattered in another company
System formed in continuous water phase, referred to as W/O/W types corpus mamillare；O/W type corpus mamillares are scattered in another continuous oil phase
The system for being formed, referred to as O/W/O types corpus mamillare.Multiplet corpus mamillare has unique " two film three-phases " structure, make its
The field such as food, medicine and cosmetics and material has a very wide range of applications prospect.Multiple corpus mamillare cosmetics are due to having
Excellent skin sense and its advantage in effect expression, already the cosmetics novel form as great competitiveness.This corpus mamillare
Most interior phase as add active ingredient after, active ingredient will can just be discharged by two interfaces, can delay active ingredient
Rate of release, extends the action time of active ingredient, and this characteristic obtains many applications in medicine, food, cosmetics industry.
For cosmetics, it had both had the good moisturizing effect of w/o type corpus mamillare to the multiple corpus mamillare of W/O/W types, and with O/W types
The good smear of corpus mamillare, without greasy sensation.This multiple emulsus build cosmetics, can increase to skin moisture-keeping,
Product fragrance guard time can be made persistently, can be used as the comparatively ideal formulation of the cosmetics containing bioactive ingredients.
The destruction of ozone layer causes the skin diseases showed increased that global range internal cause daylight excessive exposure causes, skin
The sun-proof extensive concern for having caused people.Sunscreen product in the market is anti-by adding physical sunscreen agent and chemistry mostly
Shine agent come reach broad spectrum ultraviolet light protection effect, but physical sunscreen agent there are problems that protective capacities it is weak, it is easy block, change
Learn sun-screening agent then there are problems that photostability it is poor,.
The content of the invention
It is an object of the invention to provide a kind of gentleer, non-stimulated, while photostability and sun-proof result are more preferable
Gentle efficient multiple corpus mamillare suncream.
It is a further object of the present invention to provide the preparation method of the gentle efficient multiple corpus mamillare suncream.
To achieve the object of the present invention, present invention employs following technical scheme：A kind of gentle efficient multiple corpus mamillare
Suncream, first makes colostrumi bodies (W/O), then makes the multiple corpus mamillare (W/O/W) comprising colostrumi bodies (W/O)；Correspondingly, make
It is divided into two steps as process, first prepares colostrumi bodies (W/O), multiple corpus mamillare (W/O/W) is then prepared again.
The colostrumi bodies (W/O), is made up of the component comprising following percentage by weight：
The preparation method of the colostrumi bodies (W/O) is as follows the step of it includes：Just oil phase (grease, emulsifying agent) and water
After phase (deionized water, sunscreen composition, NMF, colloid raw material) is uniformly dissolved at 70 DEG C respectively, it is added to water before emulsification
Enter light screening composition, dispersed with stirring is uniform；After draw water and mutually enter oil phase, with 1000-3000rpm, preferred rotating speed is 2500-
3000rpm carries out emulsifying homogeneous, and emulsification times are 15-25min；After emulsification is cooled to 45 DEG C after terminating, preservative and tax are added
Pastil, stir vacuum defoamation, stand-by.
The multiple corpus mamillare (W/O/W), is made up of the component comprising following percentage by weight：
The step of preparation method of the multiple corpus mamillare (W/O/W) includes is as follows：By Aqueous Phase Raw Material (deionized water, guarantor
Humectant, colloid raw material) and oil phase raw material (grease, emulsifying agent) after dissolving is uniformly dispersed respectively at 70 DEG C, pump into water mutually breast
Change, emulsifying homogeneous speed is 1000-3000rpm, preferred speed is 2500-3000rpm, and emulsification times are 10-20min, breast
After change terminates, 50 DEG C are cooled to, the colostrumi bodies (W/O) that will be prepared is slowly added into water phase, while with 200-800rpm speed
Rate is stirred, and mixing time is 5-15min；It is cooled to 45 DEG C and adds preservative and odorant, stirs vacuum defoamation.
The grease be Parleam, carbonic acid dioctyl ester, caprylic/capric triglyceride, cetanol ethylhexoate,
Nexbase 2004, C12-15 alcohol benzoic ethers, isomery hexadecane, dimethyl silicone polymer, ring five dimethyl silicone polymer, ore deposit
One kind/two kind or more than three kinds of mixing in oil, ceresine.
The emulsifying agent is the smooth stearate of sorb, stereth -2, cetyl PEG/PPG-10/1 poly dimethyl silicon
Oxygen alkane, sorbitan sesquioleate, KF6017, polysorbate -60, stereth -21, poly- sorb
The one or two kinds of combination of the above of alcohol ester -20, Phosphoric acid monohexadecyl ester potassium.
The sunscreen composition of the colostrumi bodies (W/O) is Phenylbenzimidazolesulfonic acid, di-2-ethylhexylphosphine oxide-BTA base tetramethyl
Base butylphenol, BEMT, methyl methacrylate cross-linked polymer, zinc oxide, titanium dioxide
In one kind, the combination of two kinds or more than three kinds.
Described NMF be glycerine, butanediol, 1,3-PD, Sodium Hyaluronate, PEG-8 in one kind or
Two or more combinations.
The colloid raw material is xanthan gum, starch, Carbomer, AVC, acrylic acid
One or more combination in polymer, Sodium Polyacrylate.
Compared with prior art, the beneficial effects of the invention are as follows：With reference to the multiple emulsified bodies of W/O/W special " two film three-phases "
Structure, the chemical sun that will have potential stimulus is added in most interior phase, and chemical sun on the one hand is carried out into certain journey
The protection of degree, solves the problems, such as its photostability, on the other hand reduces the concentration of chemical sun and direct skin contact,
Excitant is reduced to a certain extent；Therefore, multiple corpus mamillare suncream product compares general substance emulsified body sunscreen product, meeting
It is gentleer, non-stimulated, while sun-proof result also can be more preferably；With very big application prospect.
Specific embodiment
Below by way of specific embodiment come the present invention is further illustrated, but these embodiments simply to illustrate that,
It is not limitation of the present invention.
The multiple corpus mamillare suncream (I) of embodiment 1
A kind of gentle efficient multiple corpus mamillare suncream (skin nursing with multiple corpus mamillare suncream), it has following matching somebody with somebody
The component composition of square table, concrete component is shown in Table 1, table 2.
The colostrumi bodies of table 1 (W/O) is formulated
The multiple corpus mamillare (W/O/W) of table 2 is formulated
The preparation method of the gentle efficient multiple corpus mamillare suncream, it is comprised the following steps that：
The preparation method of colostrumi bodies (W/O) is as follows the step of it includes：By oil phase (grease, emulsifying agent) and water phase (go from
Sub- water, sunscreen composition, NMF, colloid raw material) be uniformly dissolved at 70 DEG C respectively after, emulsification before be added to sun-screening agent to water
Composition, dispersed with stirring is uniform；After draw water and mutually enter oil phase, emulsifying homogeneous are carried out with 2000rpm, emulsification times are 20min；Emulsification
After 45 DEG C are cooled to after end, preservative and odorant are added, stir vacuum defoamation, stand-by.
The preparation of multiple corpus mamillare (W/O/W)：Aqueous Phase Raw Material (deionized water, NMF, colloid raw material) and oil phase is former
Material (grease, emulsifying agent) dissolves after being uniformly dispersed respectively at 70 DEG C, pumps and is mutually emulsified into water, and emulsifying homogeneous speed is
2500rpm, emulsification times are 15min, after emulsification terminates, are cooled to 50 DEG C, and the colostrum (W/O) that will be prepared is slowly added into water
Xiang Zhong, while being stirred with 500rpm speed, mixing time is 10min；It is cooled to 45 DEG C and adds preservative and odorant, stirring is equal
Even vacuum defoamation.
The multiple corpus mamillare suncream (II) of embodiment 2
A kind of gentle efficient multiple corpus mamillare suncream (skin nursing with multiple corpus mamillare suncream), it has following matching somebody with somebody
The component composition of square table, concrete component is shown in Table 3, table 4.
The colostrumi bodies of table 3 (W/O) is formulated
The multiple corpus mamillare (W/O/W) of table 4 is formulated
The preparation method of the gentle efficient multiple corpus mamillare suncream, it is comprised the following steps that：
The preparation method of colostrumi bodies (W/O) is as follows the step of it includes：By oil phase (grease, emulsifying agent) and water phase (go from
Sub- water, sunscreen composition, NMF, colloid raw material) be uniformly dissolved at 70 DEG C respectively after, emulsification before be added to sun-screening agent to water
Composition, dispersed with stirring is uniform；After draw water and mutually enter oil phase, emulsifying homogeneous are carried out with 2900rpm, emulsification times are 22min；Emulsification
After 45 DEG C are cooled to after end, preservative and odorant are added, stir vacuum defoamation, stand-by.
The preparation of multiple corpus mamillare (W/O/W)：Aqueous Phase Raw Material (deionized water, NMF, colloid raw material) and oil phase is former
Material (grease, emulsifying agent) dissolves after being uniformly dispersed respectively at 70 DEG C, pumps and is mutually emulsified into water, and emulsifying homogeneous speed is
1500rpm, emulsification times are 15min, after emulsification terminates, are cooled to 50 DEG C, and the colostrum (W/O) that will be prepared is slowly added into water
Xiang Zhong, while being stirred with 600rpm speed, mixing time is 14min；It is cooled to 45 DEG C and adds preservative and odorant, stirring is equal
Even vacuum defoamation.
The multiple corpus mamillare suncream (III) of embodiment 3
A kind of gentle efficient multiple corpus mamillare suncream (skin nursing with multiple corpus mamillare suncream), it has following matching somebody with somebody
The component composition of square table, concrete component is shown in Table 5, table 6.
The colostrumi bodies of table 5 (W/O) is formulated
The multiple corpus mamillare (W/O/W) of table 6 is formulated
The preparation method of the gentle efficient multiple corpus mamillare suncream, it is comprised the following steps that：
The preparation method of colostrumi bodies (W/O) is as follows the step of it includes：By oil phase (grease, emulsifying agent) and water phase (go from
Sub- water, sunscreen composition, NMF, colloid raw material) be uniformly dissolved at 70 DEG C respectively after, emulsification before be added to sun-screening agent to water
Composition, dispersed with stirring is uniform；After draw water and mutually enter oil phase, emulsifying homogeneous are carried out with 2800rpm, emulsification times are 20min；Emulsification
After 45 DEG C are cooled to after end, preservative and odorant are added, stir vacuum defoamation, stand-by.
The preparation of multiple corpus mamillare (W/O/W)：Aqueous Phase Raw Material (deionized water, NMF, colloid raw material) and oil phase is former
Material (grease, emulsifying agent) dissolves after being uniformly dispersed respectively at 70 DEG C, pumps and is mutually emulsified into water, and emulsifying homogeneous speed is
2500rpm, emulsification times are 16min, after emulsification terminates, are cooled to 50 DEG C, and the colostrum (W/O) that will be prepared is slowly added into water
Xiang Zhong, while being stirred with 500rpm speed, mixing time is 10min；It is cooled to 45 DEG C and adds preservative and odorant, stirring is equal
Even vacuum defoamation.
Effect experiment
Test 1 sensory evaluation
● moisture-keeping efficacy evaluation experimental
According to light industry standard QB/T 4256-2011 cosmetics moisture-keeping efficacy evaluation guides, from of the invention gentle high
Multiple corpus mamillare suncream and commercially available certain brand of effect are sold fast suncream (substance emulsified body), determine its moistening effect.
Method of testing：Healthy volunteer 30, the age was at 20~50 years old.In isoperibol (22 ± 1 DEG C), relative humidity 50
± 5%, after 1 hour of rest.By (2.0 ± 0.1) mg/cm2 consumption samples be coated in subject's left hand inner forearm (4cm ×
4cm) with right forearm inner side (4cm × 4cm).Blank (not applying) is while test.Respectively be painted with sample 2 hours, 4
Hour, 6 hours, 8 hours test the hydrauture state of skin.Evaluation result hydrauture average value represents, is shown in Table 7 institutes
Show.
The hydrauture of the different time product of table 7
Result shows that the water skin of gentle efficient multiple corpus mamillare suncream is right after 8h still 54.32%, and commercially available
Skin hydration degree is reduced to 38.39% after product 8h.Illustrate that gentle efficient multiple corpus mamillare suncream has compared to contrast product
More preferable moistening effect.
● sensory evaluation
It is right from gentle efficient multiple corpus mamillare suncream product of the invention in order to evaluate using effect of the invention
Than commercially available common sunscreen frost product.Choosing 30 usually has the female consumer being accustomed to using suncream product to carry out for 20~50 years old
Product sensory evaluation test, subject adheres to using product daily, and sensory evaluation is carried out to product after 1 month, and its result is such as
(counted per capita, digitized representation more approves the number of the assessment item of product) shown in table 8 below.
The product sensory evaluation of table 8
To can be seen that this product preferably salubrious with respect to having for commercially available prod for the evaluation result of user from table 8
Degree and smear, moisturizing degree are very nearly the same with commercially available prod with comfortableness, and overall use feeling is better than commercially available prod.
Test the test of 2 sun-proof functions
1st, SPF (SPF)：Also referred to as sun protection coefficient, shows the height of the sun-proof efficiency that sun-proof articles can be played
It is low.Spf value is bigger, and sun-proof result is better.It is the minimum Erythema Dose (MED) according to skin come what is determined.Use Sun block
After product, the minimum Erythema Dose of skin can increase, then the SPF SPF of the sun-proof articles is then：
SPF indexes are applied to the protection effect evaluated to UVB.
2nd, sun care preparations long wave ultraviolet protection index (PFA values)：Also referred to as UVA protection index.UVA is irradiated in daylight
Skin, the physiological effect of main generation skin melanism, effect is measured with minimal persistent pigment dose (MPPD).MPPD is
Minimum ultraviolet irradiation dose or most short irradiation needed for 2~4h produces slight melanism on whole irradiated site skin after irradiation
Time.
Using SPF-290 type instrument test methods come the spf value of determination sample and PFA values.First with the filter that instrument is subsidiary in itself
Piece and standard items carry out a detection examination, carry out sample test after all going well again.First determine the background curve of blank film, Ran Houyong
Sample applicator uniform point sample-adding product on 3M adhesive tapes, are smeared with the finger with latex finger-stall, make the sample on film surface with 2 μ L/
cm2Distribution.Then the sample panel after smearing is placed in 37 DEG C of thermostatic drying chamber and is dried, with SPF-290 analyzers transparent
6 point tests are randomly selected on film.Work station processing data is finally utilized, corresponding spf value or PFA values is obtained.Contrast test
Result is as shown in table 9.
The SPF of the contrast product of table 9
Test 3 patch tests
Reference《Cosmetics health specification》The method of (2007 editions)-human skin patch is tested.Selection 40
The volunteer of the requirement of Pass Test in 18~60 years old is used as study subject (each 20 of men and women).Sample (tested material) is added into spot examination device
Interior, consumption is 0.020~0.025g.Control wells are blank (not putting any material).To be used added with the spot of tested material examination device
The forearm that non-stimulated adhesive tape is pasted on subject bends side, is gently pressed with palm, is allowed to equably be pasted on skin.Do at experiment position
Good mark, to observe.Sticked once every 24h, open 30min after paster, dermoreaction is observed after impression disappears.If
Suspicious reaction or positive reaction, then subject stopping carry out patch test；If negative reaction, then receive the subject is same
Examination position proceeds as above patch test, and 6 patch experiments are repeated altogether.Test population reaction result is recorded by table 10.
Result is as shown in table 11.
The skin adverse reaction grade scale of table 10
The patch test results of table 11
By the experimental result of table 14, gentle efficient multiple corpus mamillare suncream is non-stimulated to skin, no positive reaction, and compares
Compared with the positive reaction that the commercially available prod of example there are 2 times, there is certain stimulation to skin.Therefore, multiple corpus mamillare suncream product phase
Compared with common product, more gently, non-stimulated.
Preferred embodiment of the invention described in detail above, be inventor take a large amount of manpower financial capacities and when
Between, test of many times out it will be appreciated that, as a result, the ordinary skill of this area without creative work just can according to this
Many modifications and variations are made in the design of invention.Therefore, all technical staff in the art according to present inventive concept in existing skill
By logic analysis, reasoning or according to the limited available technical scheme of experiment on the basis of art, should be by this power
Among protection domain determined by sharp claim.
Claims (8)
1. a kind of gentle efficient multiple corpus mamillare suncream, it is characterised in that first make colostrumi bodies, then make and include colostrum
The multiple corpus mamillare of body；
The colostrumi bodies, is made up of the component comprising following percentage by weight：
The multiple corpus mamillare, is made up of the component comprising following percentage by weight：
2. a kind of gentle efficient multiple corpus mamillare suncream according to claim 1, it is characterised in that the grease is
Parleam, carbonic acid dioctyl ester, caprylic/capric triglyceride, cetanol ethylhexoate, Nexbase 2004, C12-15
More than three kinds in alcohol benzoic ether, isomery hexadecane, dimethyl silicone polymer, ring five dimethyl silicone polymer, Dormant oils, ceresine
Mixing.
3. a kind of gentle efficient multiple corpus mamillare suncream according to claim 1, it is characterised in that the emulsifying agent
It is the smooth stearate of sorb, stereth -2, cetyl PEG/PPG-10/1 dimethyl silicone polymers, the smooth sesquialter oleic acid of sorb
Ester, KF6017, polysorbate -60, stereth -21, polysorbate -20, cetanol phosphoric acid
The two or more combination of ester potassium.
4. a kind of gentle efficient multiple corpus mamillare suncream according to claim 1, it is characterised in that the colostrumi bodies
Sunscreen composition be Phenylbenzimidazolesulfonic acid, MBBT, double-ethyl hexyl oxygen benzene
More than three kinds in phenol anisyl triazine, methyl methacrylate cross-linked polymer, zinc oxide, titanium dioxide of combination.
5. a kind of gentle efficient multiple corpus mamillare suncream according to claim 1, it is characterised in that described moisturizing
Agent is one or more the combination in glycerine, butanediol, 1,3-PD, Sodium Hyaluronate, PEG-8.
6. a kind of gentle efficient multiple corpus mamillare suncream according to claim 1, it is characterised in that the colloid is former
Expect to be xanthan gum, starch, Carbomer, AVC, acrylate copolymer, Sodium Polyacrylate
In one or more combination.
7. the preparation method of a kind of gentle efficient multiple corpus mamillare suncream according to claim 1, it is characterised in that
Including the step of it is as follows：
The preparation method of colostrumi bodies is as follows the step of it includes：After oil phase and Aqueous Phase Raw Material are uniformly dissolved at 70 DEG C respectively,
Light screening composition is added to water before emulsification, dispersed with stirring is uniform；After draw water and mutually enter oil phase, breast is carried out with 1000-3000rpm
Change homogeneous, emulsification times are 15-25min；After emulsification is cooled to 45 DEG C after terminating, preservative and odorant are added, stirred
Vacuum defoamation；
The step of preparation method of multiple corpus mamillare includes is as follows：The dissolving point respectively at 70 DEG C by Aqueous Phase Raw Material and oil phase raw material
After dissipating uniformly, pump and mutually emulsified into water, emulsifying homogeneous speed is 1000-3000rpm, and emulsification times are 10-20min, emulsification knot
Shu Hou, is cooled to 50 DEG C, and the colostrumi bodies that will be prepared is slowly added into water phase, while being stirred with 200-800rpm speed, stirs
The time is mixed for 5-15min；It is cooled to 45 DEG C and adds preservative and odorant, stirs vacuum defoamation.
8. the preparation method of a kind of gentle efficient multiple corpus mamillare suncream according to claim 7, it is characterised in that
Emulsifying homogeneous speed is 2500-3000rpm.
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| CN107648056A (en) * | 2017-09-27 | 2018-02-02 | 广州环亚化妆品科技有限公司 | A kind of suntan lotion and preparation method thereof |
| CN107693395A (en) * | 2017-09-21 | 2018-02-16 | 诺斯贝尔化妆品股份有限公司 | A kind of oil-in-water type phase inversion element face frost |
| CN108379159A (en) * | 2018-04-20 | 2018-08-10 | 西安博和医疗科技有限公司 | A kind of transparent sun protection gel product and preparation method thereof |
| CN109498474A (en) * | 2018-12-12 | 2019-03-22 | 中山中研化妆品有限公司 | A kind of salubrious three-phase Emulsified sunscreen cosmetic and preparation method thereof |
| CN109512682A (en) * | 2018-12-29 | 2019-03-26 | 浙江大学华南工业技术研究院 | A kind of multiple-phase emulsion, preparation method and its application with protection natural water-soluble colorants function |
| CN109908004A (en) * | 2019-04-23 | 2019-06-21 | 广东芭薇生物科技股份有限公司 | A kind of multiple emulsion sunscreen cosmetic and preparation method thereof |
| CN110063901A (en) * | 2019-03-18 | 2019-07-30 | 曼秀雷敦(中国)药业有限公司 | A kind of sun-proof creams and preparation method thereof suitable for sensitive flesh |
| CN111631995A (en) * | 2020-06-10 | 2020-09-08 | 广东柏俐臣生物科技有限公司 | Multiplex eye cream and preparation method thereof |
| CN115350099A (en) * | 2022-08-26 | 2022-11-18 | 广州栋方生物科技股份有限公司 | Emulsification method and application of oil-in-water type sunscreen composition |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107693395A (en) * | 2017-09-21 | 2018-02-16 | 诺斯贝尔化妆品股份有限公司 | A kind of oil-in-water type phase inversion element face frost |
| CN107648056A (en) * | 2017-09-27 | 2018-02-02 | 广州环亚化妆品科技有限公司 | A kind of suntan lotion and preparation method thereof |
| CN108379159A (en) * | 2018-04-20 | 2018-08-10 | 西安博和医疗科技有限公司 | A kind of transparent sun protection gel product and preparation method thereof |
| CN109498474A (en) * | 2018-12-12 | 2019-03-22 | 中山中研化妆品有限公司 | A kind of salubrious three-phase Emulsified sunscreen cosmetic and preparation method thereof |
| CN109512682A (en) * | 2018-12-29 | 2019-03-26 | 浙江大学华南工业技术研究院 | A kind of multiple-phase emulsion, preparation method and its application with protection natural water-soluble colorants function |
| CN109512682B (en) * | 2018-12-29 | 2022-03-25 | 浙江大学华南工业技术研究院 | Multiple emulsion with function of protecting natural water-soluble pigment, preparation method and application thereof |
| CN110063901A (en) * | 2019-03-18 | 2019-07-30 | 曼秀雷敦(中国)药业有限公司 | A kind of sun-proof creams and preparation method thereof suitable for sensitive flesh |
| CN109908004B (en) * | 2019-04-23 | 2021-11-16 | 广东芭薇生物科技股份有限公司 | Multiple emulsion sunscreen cosmetic and preparation method thereof |
| CN109908004A (en) * | 2019-04-23 | 2019-06-21 | 广东芭薇生物科技股份有限公司 | A kind of multiple emulsion sunscreen cosmetic and preparation method thereof |
| CN111631995A (en) * | 2020-06-10 | 2020-09-08 | 广东柏俐臣生物科技有限公司 | Multiplex eye cream and preparation method thereof |
| CN111631995B (en) * | 2020-06-10 | 2021-06-04 | 广东柏俐臣生物科技有限公司 | Multiplex eye cream and preparation method thereof |
| CN115350099A (en) * | 2022-08-26 | 2022-11-18 | 广州栋方生物科技股份有限公司 | Emulsification method and application of oil-in-water type sunscreen composition |
| CN115350099B (en) * | 2022-08-26 | 2023-12-29 | 广州栋方生物科技股份有限公司 | Emulsification method of oil-in-oil type sun-screening composition and application thereof |
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Address after: 510663 Guangzhou High-tech Industrial Development Zone, Guangzhou, Guangdong Province, 15 Kelin Road, Guangzhou Science City Patentee after: Guangzhou Huanya cosmetics technology Co.,Ltd. Address before: 510663 Guangzhou High-tech Industrial Development Zone, Guangzhou, Guangdong Province, 15 Kelin Road, Guangzhou Science City Patentee before: GUANGZHOU HUANYA COSMETICS TECHNOLOGY Co.,Ltd. |