CN1068205C - Compound Chinese proprietary medicine for treating asthma of animal-"Kechuanwang" and preparation method thereof - Google Patents
Compound Chinese proprietary medicine for treating asthma of animal-"Kechuanwang" and preparation method thereof Download PDFInfo
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- CN1068205C CN1068205C CN95106988A CN95106988A CN1068205C CN 1068205 C CN1068205 C CN 1068205C CN 95106988 A CN95106988 A CN 95106988A CN 95106988 A CN95106988 A CN 95106988A CN 1068205 C CN1068205 C CN 1068205C
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- radix
- herba
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Abstract
The present invention relates to compound Chinese proprietary medicine for animals, which is prepared from common anemarrhena rhizome, Sichuan coptis root, platycodon root, green chiretta, borneol, Sichuan fritillary bulb, isatis root, sulphur, oriental wormwood, cassia bark, realgar, quinethanol, liquorice, ephedra and ophiopogon. The medicinal materials are pulverized, screened and uniformly mixed to obtain medicinal powder, or auxiliary materials are added to the powder, and the mixture is tabletted to obtain tablets; the medicinal materials are pulverized, decocted with water, filtered, concentrated, dried and pulverized, so water-soluble powder is obtained. The compound Chinese proprietary medicine of the present invention has obvious curative effect on chicken septico-mycoplasma diseases, colibacillosis, the combined infection diseases of the chicken septico-mycoplasma diseases and the colibacillosis, poultry pasteurellosis, poultry white diarrhea, etc.
Description
The present invention relates to a kind of veterinary drug and preparation method thereof, especially a kind ofly make, be used for the treatment of Chinese patent medicine of poultry disease and preparation method thereof with Chinese herbal medicine and Western medicine compound recipe.
Mycoplasma galliseplicum disease (being chronic respiratory disease) and chicken colibacillosis and both blended infection, be commonly encountered diseases and the frequently-occurring disease of chicken, its preventing and controlling become the problem that vast veterinary work person and foster fowl specialist are concerned about for a long time always, also are world-famous puzzles.The medicine that is used for the treatment of at present mainly contains kitasamycin, norfloxacin and safe wonderful spirit, though these Western medicine have certain effect, curative effect is not satisfactory.The present inventor once studied with Chinese herbal and crude drugs preparations and treated fowl diseases, as the disclosed antimicrobial " Kangjunling " as animal remedy of CN1085787A.This medicine is remarkable to the more similar medicine of chicken colibacillosis curative effect, but not satisfactory to mycoplasma galliseplicum disease.
The objective of the invention is to overcome the shortcoming of prior art, provide a kind of mycoplasma galliseplicum disease and chicken colibacillosis good effect, compound Chinese patent medicine that toxicity is low and preparation method thereof.
For achieving the above object, compound Chinese patent medicine of the present invention is formulated with the Rhizoma Anemarrhenae, Rhizoma Coptidis, Radix Platycodonis, Herba Andrographis, Borneolum Syntheticum, Bulbus Fritillariae Cirrhosae, Radix Isatidis, sulfur, Herba Artemisiae Scopariae, Cortex Cinnamomi, Realgar, olaquindox, Radix Glycyrrhizae, Herba Ephedrae and Radix Ophiopogonis.
Described Chinese patent medicine comprises tablet, powder and water-soluble powder etc. for dosage form commonly used.
The consumption of the above-mentioned medicine of respectively distinguishing the flavor of that the present invention is used, following row weight portion is advisable: the Rhizoma Anemarrhenae 12～18, Rhizoma Coptidis 5～7, Radix Platycodonis 13～19, Herba Andrographis 4～6, Borneolum Syntheticum 0.4～0.6, Bulbus Fritillariae Cirrhosae 13～19, Radix Isatidis 5～7, sulfur 0.4～0.6, Herba Artemisiae Scopariae 2.4～3.6, Cortex Cinnamomi 2.4～3.6, Realgar 2.4～3.6, olaquindox 0.4～0.8, Radix Glycyrrhizae 4～6, Herba Ephedrae 6～9, Radix Ophiopogonis 12～18.
The preparation method of tablet is: the Rhizoma Anemarrhenae, Rhizoma Coptidis, Radix Platycodonis, Herba Andrographis, Borneolum Syntheticum, Bulbus Fritillariae Cirrhosae, Radix Isatidis, sulfur, Herba Artemisiae Scopariae, Cortex Cinnamomi, Realgar, Radix Glycyrrhizae, Herba Ephedrae, Radix Ophiopogonis are pulverized, and sieve (80 order) adds olaquindox, mixing adds adjuvant, granulates, tabletting gets Chinese patent medicine of the present invention.
The preparation method of powder is: the Rhizoma Anemarrhenae, Rhizoma Coptidis, Radix Platycodonis, Herba Andrographis, Borneolum Syntheticum, Bulbus Fritillariae Cirrhosae, Radix Isatidis, sulfur, Herba Artemisiae Scopariae, Cortex Cinnamomi, Realgar, Radix Glycyrrhizae, Herba Ephedrae, Radix Ophiopogonis are pulverized, and sieve (80 order) adds olaquindox, and mixing gets Chinese patent medicine of the present invention and looses.
The preparation method of water solube powder is: the Rhizoma Anemarrhenae, Rhizoma Coptidis, Radix Platycodonis, Herba Andrographis, Borneolum Syntheticum, Bulbus Fritillariae Cirrhosae, Radix Isatidis, sulfur, Herba Artemisiae Scopariae, Cortex Cinnamomi, Realgar, Radix Glycyrrhizae, Herba Ephedrae, Radix Ophiopogonis are pulverized, add water to the submergence spice, decocted 1～3 hour, filter, be condensed into extractum, drying, pulverize, add olaquindox, mixing gets Chinese patent medicine water solube powder of the present invention.
Provide embodiment below:
[example 1] gets Rhizoma Anemarrhenae 15g, Rhizoma Coptidis 6g, Radix Platycodonis 16g, Herba Andrographis 5g, Borneolum Syntheticum 0.5g, Bulbus Fritillariae Cirrhosae 16g, Radix Isatidis 6g, sulfur 0.5g, Herba Artemisiae Scopariae 3g, Cortex Cinnamomi 3g, Realgar 3g, Radix Glycyrrhizae 5g, Herba Ephedrae 7.4g, 15g pulverizing Radix Ophiopogonis, cross 80 mesh sieves, add olaquindox 0.6g, mixing, add adjuvants such as starch, granulate, tabletting gets Chinese patent medicine.Be used for the treatment of mycoplasma galliseplicum disease and colibacillosis, and hemorrhagic septicemia of fowl, pullorum disease etc., sneak in 0.7% ratio and take in the feedstuff, once a day, serve on 3 days.Initial dose doubles, and dosage reduces by half when being used to prevent.
[example 2] gets Rhizoma Anemarrhenae 13g, Rhizoma Coptidis 5g, Radix Platycodonis 14g, Herba Andrographis 5g, Borneolum Syntheticum 0.4g, Bulbus Fritillariae Cirrhosae 14g, Radix Isatidis 5g, sulfur 0.4g, Herba Artemisiae Scopariae 2.4g, Cortex Cinnamomi 2.5g, Realgar 2.4g, Radix Glycyrrhizae 4g, Herba Ephedrae 7g, 13g pulverizing Radix Ophiopogonis.Sieve in (80 order), add olaquindox 0.6g, mixing gets Chinese patent medicine and looses.Be used for the treatment of mycoplasma galliseplicum disease, colibacillosis, hemorrhagic septicemia of fowl, pullorum disease etc., in feedstuff, once a day, serve on 3 days by 0.7% mixed.Double first, prevention reduces by half.
[example 3] gets Rhizoma Anemarrhenae 18g, Rhizoma Coptidis 6g, Radix Platycodonis 19g, Herba Andrographis 6g, Borneolum Syntheticum 0.5g, Bulbus Fritillariae Cirrhosae 18g, Radix Isatidis 7g, sulfur 0.6g, Herba Artemisiae Scopariae 3.6g, Cortex Cinnamomi 3.6g, Realgar 3.6g, Radix Glycyrrhizae 6g, Herba Ephedrae 8g, 18g pulverizing Radix Ophiopogonis, add water to and just soaked spice, decocted 2 hours, filter, filtrate is concentrated, dry, pulverizing, add olaquindox 0.6g, mixing gets the Chinese patent medicine water solube powder.Be used for the treatment of mycoplasma galliseplicum disease and colibacillosis, and hemorrhagic septicemia of fowl, pullorum disease etc., add diseases caused by retention of fluid usefulness in 1: 100～200 ratios, every day 1 time, serve on 3 days.First dose doubles, and prevention reduces by half.
Compound Chinese patent medicine of the present invention is tested through the animal doctor of Agricultural University Of South China Pharmacology Lab clinical treatment, Mycoplasma galliseplicum disease and colibacillosis are had good curative effect, and result for the treatment of obviously is better than fluorine Croak acid, Kitasamycin and safe wonderful spirit, and be better than next three kinds of west aspect relief of symptoms and the weightening finish Medicine, result such as following table.
Chinese patent drug of the present invention and orfloxacin, Kitasamycin, safe wonderful clever therapeutic test result are relatively
| Grouping | Dosage | The animal number of elements | Average weight gain (kg) X ± SD | The antibody positive reactivity | The death rate | Mycoplasma galliseplicum disease (sampling observation) | Escherichia coli separate recall rate (sampling observation) | Clinical symptoms | ||
| Control group | Normal healthy controls (not inoculating not administration) | 22 | 0.433±0.134 | 1/22 | 0/22 | 0/5 | 0/5 | 0/22 | ||
| Negative (infection) contrast (inoculation, not administration) | 22 | 0.230±0.122 | 16/16 | 6/22 | 5/5 | 5/5 | 16/16 | |||
| The dispensing group | Chinese patent drug of the present invention | Powder | 0.8g/kg | 22 | 0.374±0.123 | 5/22 | 0/22 | 0/5 | 0/5 | 0/22 |
| Decoction | 0.8ml/kg 0.8g/kg | 22 | 0.362±0.131 | 7/22 | 0/22 | 0/5 | 0/5 | 0/22 | ||
| Water solube powder | 4ml／kg 0.8g/kg | 22 | 0.374±0.147 | 5/21 | 1/22 | 1/5 | 1/5 | 3/21 | ||
| Other drug | Orfloxacin | 10mg/kg | 22 | 0.247±0.130 | 3/19 | 3/22 | 3/5 | 2/5 | 12/19 | |
| Kitasamycin | 40mg/kg | 22 | 0.371±0.153 | 5/21 | 1/22 | 1/5 | 1/5 | 3/21 | ||
| Safe wonderful spirit | 20mg/kg | 22 | 0.356±0.170 | 14/21 | 1/22 | 1/5 | 1/5 | 6/21 | ||
Claims (4)
1, a kind of veterinary drug compound Chinese patent medicine, it is characterized in that by the Rhizoma Anemarrhenae, Rhizoma Coptidis, Radix Platycodonis, Herba Andrographis, Borneolum Syntheticum, Bulbus Fritillariae Cirrhosae, Radix Isatidis, sulfur, Herba Artemisiae Scopariae, Cortex Cinnamomi, Realgar, olaquindox, Radix Glycyrrhizae, Herba Ephedrae and Radix Ophiopogonis are formulated, the following row weight portion of the consumption of the medicine of wherein respectively distinguishing the flavor of: the Rhizoma Anemarrhenae 12～18, Rhizoma Coptidis 5～7, Radix Platycodonis 13～19, Herba Andrographis 4～6, Borneolum Syntheticum 0.4～0.6, Bulbus Fritillariae Cirrhosae 13～19, Radix Isatidis 5～7, sulfur 0.4～0.6, Herba Artemisiae Scopariae 2.4～3.6, Cortex Cinnamomi 2.4～3.6, Realgar 2.4～3.6, olaquindox 0.4～0.8, Radix Glycyrrhizae 4～6, Herba Ephedrae 6～9, Radix Ophiopogonis 12～18.
2, a kind of preparation method of veterinary drug compound Chinese patent medicine tablet, it is characterized in that the Rhizoma Anemarrhenae, Rhizoma Coptidis, Radix Platycodonis, Herba Andrographis, Borneolum Syntheticum, Bulbus Fritillariae Cirrhosae, Radix Isatidis, sulfur, Herba Artemisiae Scopariae, Cortex Cinnamomi, Realgar, Radix Glycyrrhizae, Herba Ephedrae, Radix Ophiopogonis are pulverized, (80 order) sieves, add olaquindox, mixing adds adjuvant, granulates, tabletting gets Chinese patent medicine.
3, a kind of preparation method of veterinary drug compound Chinese patent medicine powder, it is characterized in that with the Rhizoma Anemarrhenae, Rhizoma Coptidis, Radix Platycodonis, Herba Andrographis, Borneolum Syntheticum, Bulbus Fritillariae Cirrhosae, Radix Isatidis, sulfur, Herba Artemisiae Scopariae, Cortex Cinnamomi, Realgar, Radix Glycyrrhizae, Herba Ephedrae, Radix Ophiopogonis pulverize, (80 order) sieves, add olaquindox, mixing gets Chinese patent medicine and looses.
4, a kind of preparation method of veterinary drug compound Chinese patent medicine water solube powder, it is characterized in that the Rhizoma Anemarrhenae, Rhizoma Coptidis, Radix Platycodonis, Herba Andrographis, Borneolum Syntheticum, Bulbus Fritillariae Cirrhosae, Radix Isatidis, sulfur, Herba Artemisiae Scopariae, Cortex Cinnamomi, Realgar, Radix Glycyrrhizae, Herba Ephedrae, Radix Ophiopogonis are pulverized, add water in the submergence spice, decocted 1～3 hour, filter, be condensed into extractum, drying is pulverized, and adds olaquindox, mixing gets Chinese patent medicine compound recipe water solube powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95106988A CN1068205C (en) | 1995-08-03 | 1995-08-03 | Compound Chinese proprietary medicine for treating asthma of animal-"Kechuanwang" and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95106988A CN1068205C (en) | 1995-08-03 | 1995-08-03 | Compound Chinese proprietary medicine for treating asthma of animal-"Kechuanwang" and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1117870A CN1117870A (en) | 1996-03-06 |
| CN1068205C true CN1068205C (en) | 2001-07-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95106988A Expired - Fee Related CN1068205C (en) | 1995-08-03 | 1995-08-03 | Compound Chinese proprietary medicine for treating asthma of animal-"Kechuanwang" and preparation method thereof |
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| CN (1) | CN1068205C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1888903B (en) * | 2006-08-08 | 2010-08-11 | 中国农业科学院农业质量标准与检测技术研究所 | Enzyme-linked immune assay kit for detecting olaquindox |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057688C (en) * | 1996-09-10 | 2000-10-25 | 康寿昆 | Physiological balancing agent for livestock and fowls |
| CN103751517A (en) * | 2014-01-06 | 2014-04-30 | 崔磊 | Pharmaceutical composition for treating chronic bronchitis |
| CN103830404B (en) * | 2014-03-11 | 2016-02-03 | 李伟跃 | The treatment Chinese medicine composition of chicken colibacillosis, the preparation method of herb mixture and herb mixture |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN88105210A (en) * | 1988-01-29 | 1988-09-28 | 赵从勤 | The manufacture method of bactericide powder for poultry |
| CN1076118A (en) * | 1993-01-08 | 1993-09-15 | 薛选清 | Antimicrobial " Kangjunling " as animal remedy and preparation method thereof |
| CN1085787A (en) * | 1992-12-02 | 1994-04-27 | 薛选清 | Antimicrobial " Kangjunling " as animal remedy and preparation method thereof |
-
1995
- 1995-08-03 CN CN95106988A patent/CN1068205C/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN88105210A (en) * | 1988-01-29 | 1988-09-28 | 赵从勤 | The manufacture method of bactericide powder for poultry |
| CN1085787A (en) * | 1992-12-02 | 1994-04-27 | 薛选清 | Antimicrobial " Kangjunling " as animal remedy and preparation method thereof |
| CN1076118A (en) * | 1993-01-08 | 1993-09-15 | 薛选清 | Antimicrobial " Kangjunling " as animal remedy and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1888903B (en) * | 2006-08-08 | 2010-08-11 | 中国农业科学院农业质量标准与检测技术研究所 | Enzyme-linked immune assay kit for detecting olaquindox |
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| Publication number | Publication date |
|---|---|
| CN1117870A (en) | 1996-03-06 |
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