CN1068201C - 嗜酸性白细胞浸润抑制剂 - Google Patents
嗜酸性白细胞浸润抑制剂 Download PDFInfo
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- CN1068201C CN1068201C CN93120515A CN93120515A CN1068201C CN 1068201 C CN1068201 C CN 1068201C CN 93120515 A CN93120515 A CN 93120515A CN 93120515 A CN93120515 A CN 93120515A CN 1068201 C CN1068201 C CN 1068201C
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- hydrogen
- intiltration
- inhibitor
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- 229960003444 immunosuppressant agent Drugs 0.000 description 1
- 230000001861 immunosuppressant effect Effects 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 239000007928 intraperitoneal injection Substances 0.000 description 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 239000003199 leukotriene receptor blocking agent Substances 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 229940040145 liniment Drugs 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229940049920 malate Drugs 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000001624 naphthyl group Chemical group 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000003650 oxygenase inhibitor Substances 0.000 description 1
- 229960001412 pentobarbital Drugs 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- CYQAYERJWZKYML-UHFFFAOYSA-N phosphorus pentasulfide Chemical compound S1P(S2)(=S)SP3(=S)SP1(=S)SP2(=S)S3 CYQAYERJWZKYML-UHFFFAOYSA-N 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- LPNYRYFBWFDTMA-UHFFFAOYSA-N potassium tert-butoxide Chemical compound [K+].CC(C)(C)[O-] LPNYRYFBWFDTMA-UHFFFAOYSA-N 0.000 description 1
- 239000000296 purinergic P1 receptor antagonist Substances 0.000 description 1
- 238000012797 qualification Methods 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000003637 steroidlike Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 229940086735 succinate Drugs 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000012622 synthetic inhibitor Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 208000037816 tissue injury Diseases 0.000 description 1
- 229950004288 tosilate Drugs 0.000 description 1
- 125000001680 trimethoxyphenyl group Chemical group 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP281653/92 | 1992-10-20 | ||
| JP28165392 | 1992-10-20 | ||
| JP281653/1992 | 1992-10-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1095594A CN1095594A (zh) | 1994-11-30 |
| CN1068201C true CN1068201C (zh) | 2001-07-11 |
Family
ID=17642105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93120515A Expired - Fee Related CN1068201C (zh) | 1992-10-20 | 1993-10-20 | 嗜酸性白细胞浸润抑制剂 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5478823A (cg-RX-API-DMAC10.html) |
| EP (1) | EP0617961A4 (cg-RX-API-DMAC10.html) |
| JP (1) | JP3163631B2 (cg-RX-API-DMAC10.html) |
| KR (1) | KR100293684B1 (cg-RX-API-DMAC10.html) |
| CN (1) | CN1068201C (cg-RX-API-DMAC10.html) |
| AU (1) | AU671865B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2126217A1 (cg-RX-API-DMAC10.html) |
| FI (1) | FI942962A7 (cg-RX-API-DMAC10.html) |
| NO (1) | NO942310L (cg-RX-API-DMAC10.html) |
| TW (1) | TW272127B (cg-RX-API-DMAC10.html) |
| WO (1) | WO1994008581A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19814838C2 (de) * | 1998-04-02 | 2001-01-18 | Asta Medica Ag | Indolyl-3-glyoxylsäure-Derivate mit Antitumorwirkung |
| US6492364B1 (en) * | 1998-12-04 | 2002-12-10 | Toray Industries, Inc. | Triazolo and derivatives as chemokine inhibitors |
| TWI269654B (en) * | 1999-09-28 | 2007-01-01 | Baxter Healthcare Sa | N-substituted indole-3-glyoxylamide compounds having anti-tumor action |
| US20040127501A1 (en) * | 2002-09-24 | 2004-07-01 | Zhengming Chen | Therapeutic agents useful for treating pain |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1066849A (zh) * | 1991-04-23 | 1992-12-09 | 东丽株式会社 | 三环三唑并衍生物、其制造方法及用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS494478B1 (cg-RX-API-DMAC10.html) * | 1970-11-09 | 1974-02-01 | ||
| JPS529198B2 (cg-RX-API-DMAC10.html) * | 1972-04-25 | 1977-03-14 | ||
| FI925833L (fi) * | 1991-04-23 | 1992-12-22 | Toray Industries | Tricykliskt triazolderivat, dess framstaellning och dess anvaendning |
-
1993
- 1993-10-18 CA CA002126217A patent/CA2126217A1/en not_active Abandoned
- 1993-10-18 KR KR1019940702144A patent/KR100293684B1/ko not_active Expired - Fee Related
- 1993-10-18 JP JP50983994A patent/JP3163631B2/ja not_active Expired - Fee Related
- 1993-10-18 EP EP93922646A patent/EP0617961A4/en not_active Withdrawn
- 1993-10-18 WO PCT/JP1993/001492 patent/WO1994008581A1/ja not_active Ceased
- 1993-10-18 AU AU51567/93A patent/AU671865B2/en not_active Ceased
- 1993-10-20 CN CN93120515A patent/CN1068201C/zh not_active Expired - Fee Related
- 1993-11-19 TW TW082109730A patent/TW272127B/zh active
-
1994
- 1994-06-17 NO NO942310A patent/NO942310L/no unknown
- 1994-06-20 FI FI942962A patent/FI942962A7/fi not_active Application Discontinuation
- 1994-08-22 US US08/244,891 patent/US5478823A/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1066849A (zh) * | 1991-04-23 | 1992-12-09 | 东丽株式会社 | 三环三唑并衍生物、其制造方法及用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| NO942310D0 (no) | 1994-06-17 |
| FI942962A7 (fi) | 1994-08-19 |
| KR100293684B1 (ko) | 2001-09-17 |
| CA2126217A1 (en) | 1994-04-28 |
| NO942310L (no) | 1994-08-19 |
| JP3163631B2 (ja) | 2001-05-08 |
| WO1994008581A1 (fr) | 1994-04-28 |
| EP0617961A1 (en) | 1994-10-05 |
| FI942962A0 (fi) | 1994-06-20 |
| AU671865B2 (en) | 1996-09-12 |
| AU5156793A (en) | 1994-05-09 |
| EP0617961A4 (en) | 1995-03-29 |
| TW272127B (cg-RX-API-DMAC10.html) | 1996-03-11 |
| CN1095594A (zh) | 1994-11-30 |
| US5478823A (en) | 1995-12-26 |
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| CF01 | Termination of patent right due to non-payment of annual fee |