CN106811343A - Whitening anti-inflammatory antibacterial toilet soap containing vine tea general flavone and its preparation method and application - Google Patents
Whitening anti-inflammatory antibacterial toilet soap containing vine tea general flavone and its preparation method and application Download PDFInfo
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- CN106811343A CN106811343A CN201611230140.3A CN201611230140A CN106811343A CN 106811343 A CN106811343 A CN 106811343A CN 201611230140 A CN201611230140 A CN 201611230140A CN 106811343 A CN106811343 A CN 106811343A
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- vine tea
- general flavone
- ultrasonic extraction
- soap
- tea general
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Classifications
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/02—Compositions of detergents based essentially on soap on alkali or ammonium soaps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D13/00—Making of soap or soap solutions in general; Apparatus therefor
- C11D13/14—Shaping
- C11D13/16—Shaping in moulds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
- C11D9/22—Organic compounds, e.g. vitamins
- C11D9/26—Organic compounds, e.g. vitamins containing oxygen
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
- C11D9/22—Organic compounds, e.g. vitamins
- C11D9/38—Products in which the composition is not well defined
Abstract
The invention discloses a kind of whitening anti-inflammatory antibacterial toilet soap containing vine tea general flavone and its preparation method and application, the whitening anti-inflammatory antibacterial toilet soap containing vine tea general flavone is made up of following raw material:1~3 part of palm oil, 5~8 parts of olive oil, 1~3 part of NaOH, 4~7 parts of water, 1~3 part of vine tea general flavone ultrasonic extraction liquid, 0.2~0.5 part of vitamin E.The present invention is experimentally confirmed, general flavone is by reducing the activity of tyrosinase in vine tea, melanin in human body skin can be prevented to generate, so as to play the effect of whitening, can be used as the ideal chose of natural plant whitening skin care item, new foundation is provided for vine tea is developed into new cosmetic skincare product, makes to be provided with wide application prospect and commercial value as the vine tea of conventional medicament.
Description
Technical field
It is particularly a kind of containing the whitening anti-inflammatory antibacterial toilet soap of vine tea general flavone and its preparation side the present invention relates to a kind of perfumed soap
Method and application, belong to the technical field of cosmetic skincare product.
Background technology
Vine tea, scientific name ampelopsis grossdentata Ampelopsis grossedentata (Hand~Mazz) W.T.Wang, category
A kind of bejuco of Vitaceae Ampelopsis, is distributed in the Yunnan Province of China southeast, Guangxi, Guangdong, Fujian, Jiangxi, lake
The ground such as south, Guizhou, West of Hubei Province.Vine tea is a kind of very ancient Chinese traditional herbs, is China's widely used medicine food among the people
Dual purpose plant, complete stool is medicinal, sweet, light, cool in nature, the effect of with clearing heat and detoxicating, wind-damp dispelling, strengthening the bones and muscles, China's successive dynasties pharmacy
Monograph and flora, such as《Herbal for Relief of Famines》、《The Illustrated Book on Plants》、《Plant name converges》、《National Chinese herbal medicine compilation》、《Seed
Botanical name》、《Quanzhou draft》、《Jiangxi medicine will》、《Zhejiang conventional herbal medicine among the people》、《Often use Chinese herbal medicine handbook in northeast》、《On
The conventional Chinese herbal medicine in sea》Deng the record for being related to vine tea.Research and application at present to vine tea pharmacological action is concentrated mainly on anti-
Oxidation, antibacterial action, hepatoprotective effect, reducing blood lipid, hypoglycemic effect, anti-inflammatory, analgesic activity, antitumor action etc., have no
There is vine tea to be applied to the relevant report of beauty and skin care.
Melanocyte is present in the basalis of human epidermal, and in melanocyte, tyrosine is urged tyrosinase
DOPA, DOPA quinone, dopachrome, 5,6-dihydroxy indole, indoles-5,6- quinones, and then shape are progressively oxidized under change effect
Into pigment granule.Skin-whitening agents are exactly to act on dermal melanin generation, metabolic process, suppress melanin generation and meet rule
The material of model, traditional skin-whitening agents are often chemical substance, such as have the mercury salt of whitening effect and the hydrogen of effect of dispelling spots
Quinone, though there is quick whitening, to skin toxic side effect, long-term use can cause contact dermatitis or permanent decolouring etc.
Adverse reaction.In recent years, people increasingly favor those safe and stable, nontoxic, non-stimulated natural plant whitening cosmetics.
Therefore, find, exploitation efficiently and human body is had no side effect or Small side effects natural Chinese medicinal herb skin-whitening and speckle eliminating preparation
One of focus as the research of current cosmetic field.
The content of the invention
The technical problems to be solved by the invention are whitening, the suppression having using the vine tea general flavone extracted from vine tea
Bacterium and antiinflammatory action, there is provided a kind of whitening anti-inflammatory antibacterial toilet soap containing vine tea general flavone and its preparation method and application, the product
It is a kind of natural plant whitening cosmetics that are safe and nontoxic, being had no side effect to human body.
In order to solve the above technical problems, the technical solution adopted by the present invention is as follows:
Whitening anti-inflammatory antibacterial toilet soap containing vine tea general flavone, the whitening anti-inflammatory antibacterial toilet soap containing vine tea general flavone is by weight
Calculating is made up of following raw material:1~3 part of palm oil, 5~8 parts of olive oil, 1~3 part of NaOH, 4~7 parts of water, vine tea are total
1~3 part of flavones ultrasonic extraction liquid, 0.2~0.5 part of vitamin E, described vine tea general flavone ultrasonic extraction liquid is to use vine tea
Meal adds the ethanol that 25~35 times of amount volume fractions are 60~80% as raw material, and ultrasonic extraction 1 after 20~40min of immersion~
3 times, 20~40min, filters and merging filtrate every time, obtains final product vine tea general flavone ultrasonic extraction liquid.
In the above-mentioned whitening anti-inflammatory antibacterial toilet soap containing vine tea general flavone, it is preferred that the weight portion of the raw material is:Palm
1 part of oil, 6 parts of olive oil, 1 part of NaOH, 5 parts of water, 1 part of vine tea general flavone ultrasonic extraction liquid, 0.3 part of vitamin E are described
Vine tea general flavone ultrasonic extraction liquid be preferably as raw material, to add the second that 30 times of amount volume fractions are 70% using vine tea meal
Alcohol, ultrasonic extraction 3 times, each 20min, filter and merging filtrate after immersion 30min, obtain final product vine tea general flavone ultrasonic extraction liquid.
The preparation method of the foregoing whitening anti-inflammatory antibacterial toilet soap containing vine tea general flavone, comprises the following steps:
Step one:Palm oil and olive oil are weighed by required weight, is put into container together, heated, fully mixed, and keep temperature
45 DEG C of degree, obtains miscella;
Step 2:Water and NaOH are weighed by required weight, NaOH is slowly added in water, side edged is stirred with alkaline-resisting
Mix device quickly to stir, NaOH is cooled to 45 DEG C after being dissolved completely in water, obtains aqueous slkali;
Step 3:Above-mentioned aqueous slkali is blown slowly in the container for pouring into dress miscella, leaned to one side while quickly being stirred with alkaline-resisting agitator
Mix, obtain soap lye;
Step 4:Ceaselessly stir, untill soap lye surface can mark 8 complete words, obtain thick soap lye;
Step 5:Adding vine tea general flavone ultrasonic extraction liquid and vitamin E while stirring in thick soap lye must mix soap lye;
Step 6:A small amount of olive oil is dipped in mould inside brush time with brush, and the mixing soap lye that step 5 is obtained is poured into mould,
Mould is covered with plastic sheeting again, is placed 1~2 day in 35 DEG C of incubators, obtain perfumed soap;
Step 7:Perfumed soap is removed from the molds, is placed at shady and cool ventilation, placed for 4 to 8 weeks, obtain perfumed soap finished product.
Application of the vine tea in cosmetic skincare product is prepared, can be made the beauty such as perfumed soap, mildy wash, shower cream, facial mask
Skincare product.
Beneficial effects of the present invention:Vine tea, is the branches and leaves of vitaceae ampelopsis, except anti-inflammatory common at present
Sterilization, reducing blood lipid, hypoglycemic, liver protecting effect are outer, and applicant has found by lot of experiments:Contain flavones in vine tea
The chemical compositions such as class, tannin class, Polyphenols, wherein flavonoids are its main chemical composition, flavone compound in vine tea
Content highest, general flavone content may be up to more than 35% in vine tea, and this is very rare in plant.And flavone compound
And its derivative has been found to suppress tyrosinase activity, tyrosinase is the ferment for producing melanin, is to cause
The main matter of human body skin pigment granule, general flavone can prevent human body skin by reducing the activity of tyrosinase in vine tea
Melanin generation in skin, so as to play the effect of whitening, can be used as the ideal chose of natural plant whitening skin care item, and vine tea
General flavone also has preferable antibacterial and antiinflammatory action, can also reach antibacterial, antiphlogistic effects while whitening, killing three birds with one stone, and
And it is natural, environmentally friendly, safe and stable, nontoxic, non-stimulated, develop vine tea and prepare the new opplication in cosmetic skincare product field, be
Vine tea is developed into new cosmetic skincare product there is provided new foundation, makes to be provided with wide answering as the vine tea of conventional medicament
With prospect and commercial value.
With reference to specific embodiment, the present invention is further illustrated.
Specific embodiment
First, the preparation of the whitening of general flavone containing vine tea anti-inflammatory antibacterial toilet soap:
Embodiment 1:Composition of raw materials:Palm oil 1kg, olive oil 6kg, NaOH 1kg, water 5kg, vine tea general flavone ultrasonic extraction
Liquid 1kg, vitamin E 0.3kg, vine tea general flavone ultrasonic extraction liquid are, as raw material, to add 30 times of amount volumes using vine tea meal
Fraction is 70% ethanol, and ultrasonic extraction 3 times, each 20min, filter and merging filtrate after immersion 30min, obtain final product.
Preparation method:Step one:Palm oil 1kg and olive oil 6kg are weighed by formula, is put into container together, heated, filled
Divide and mix, and 45 DEG C of keeping temperature, obtain miscella;
Step 2:Water 5kg and NaOH 1kg are weighed by formula, NaOH is slowly added in water, side edged is with alkaline-resisting
Agitator is quickly stirred, and NaOH is cooled to 45 DEG C after being dissolved completely in water, obtains aqueous slkali;
Step 3:Above-mentioned aqueous slkali is blown slowly in the container for pouring into dress miscella, leaned to one side while quickly being stirred with alkaline-resisting agitator
Mix, obtain soap lye;
Step 4:Ceaselessly stir, untill soap lye surface can mark 8 complete words, obtain thick soap lye;
Step 5:Add the vine tea general flavone ultrasonic extraction liquid of 1kg and the vitamin of 0.3kg while stirring in thick soap lye
E must mix soap lye;
Step 6:A small amount of olive oil is dipped in mould inside brush time with brush, and the mixing soap lye that step 5 is obtained is poured into mould,
Mould is covered with plastic sheeting again, is placed 1~2 day in 35 DEG C of incubators, obtain perfumed soap;
Step 7:Perfumed soap is removed from the molds, is placed at shady and cool ventilation, placed 6 weeks, obtain perfumed soap finished product.
Embodiment 2:Composition of raw materials:Palm oil 1kg, olive oil 5kg, NaOH 1kg, water 4kg, vine tea general flavone ultrasound
Extract solution 1kg, vitamin E 0.2kg, vine tea general flavone ultrasonic extraction liquid are, as raw material, to add 25 times of amounts using vine tea meal
Volume fraction is 80% ethanol, and ultrasonic extraction 2 times, each 30min, filter and merging filtrate after immersion 20min, obtain final product.
Preparation method:Step one:Palm oil 1kg and olive oil 5kg are weighed by formula, is put into container together, heated, filled
Divide and mix, and 45 DEG C of keeping temperature, obtain miscella;
Step 2:Water 4kg and NaOH 1kg are weighed by formula, NaOH is slowly added in water, side edged is with alkaline-resisting
Agitator is quickly stirred, and NaOH is cooled to 45 DEG C after being dissolved completely in water, obtains aqueous slkali;
Step 3:Above-mentioned aqueous slkali is blown slowly in the container for pouring into dress miscella, leaned to one side while quickly being stirred with alkaline-resisting agitator
Mix, obtain soap lye;
Step 4:Ceaselessly stir, untill soap lye surface can mark 8 complete words, obtain thick soap lye;
Step 5:Add the vine tea general flavone ultrasonic extraction liquid of 1kg and the vitamin of 0.2kg while stirring in thick soap lye
E must mix soap lye;
Step 6:A small amount of olive oil is dipped in mould inside brush time with brush, and the mixing soap lye that step 5 is obtained is poured into mould,
Mould is covered with plastic sheeting again, is placed 1~2 day in 35 DEG C of incubators, obtain perfumed soap;
Step 7:Perfumed soap is removed from the molds, is placed at shady and cool ventilation, placed 4 weeks, obtain perfumed soap finished product.
Embodiment 3:Composition of raw materials:Palm oil 3kg, olive oil 8kg, NaOH 3kg, water 7kg, vine tea general flavone ultrasound
Extract solution 3kg, vitamin E 0.5kg, vine tea general flavone ultrasonic extraction liquid are, as raw material, to add 35 times of amounts using vine tea meal
Volume fraction is 80% ethanol, and ultrasonic extraction 2 times, each 40min, filter and merging filtrate after immersion 40min, obtain final product.
Preparation method:Step one:Palm oil 3kg and olive oil 8kg are weighed by formula, is put into container together, heated, filled
Divide and mix, and 45 DEG C of keeping temperature, obtain miscella;
Step 2:Water 7kg and NaOH 3kg are weighed by formula, NaOH is slowly added in water, side edged is with alkaline-resisting
Agitator is quickly stirred, and NaOH is cooled to 45 DEG C after being dissolved completely in water, obtains aqueous slkali;
Step 3:Above-mentioned aqueous slkali is blown slowly in the container for pouring into dress miscella, leaned to one side while quickly being stirred with alkaline-resisting agitator
Mix, obtain soap lye;
Step 4:Ceaselessly stir, untill soap lye surface can mark 8 complete words, obtain thick soap lye;
Step 5:Add the vine tea general flavone ultrasonic extraction liquid of 3kg and the vitamin of 0.5kg while stirring in thick soap lye
E must mix soap lye;
Step 6:A small amount of olive oil is dipped in mould inside brush time with brush, and the mixing soap lye that step 5 is obtained is poured into mould,
Mould is covered with plastic sheeting again, is placed 1~2 day in 35 DEG C of incubators, obtain perfumed soap;
Step 7:Perfumed soap is removed from the molds, is placed at shady and cool ventilation, placed 8 weeks, obtain perfumed soap finished product.
2nd, the research of vine tea general flavone antiinflammatory action:
The antiinflammatory action of vine tea general flavone is studied using mice caused by dimethylbenzene xylene auricle edema method, is as a result shown:Vine tea is total
The high, medium and low dosage group paraxylene induced mice auricle edema of flavones has inhibitory action, and with vine tea general flavone concentration
Its swelling inhibiting rate is improved also accordingly to improve.Vine tea general flavone high dose group is notable to the inhibition of mice auricle swelling, low,
Middle dose group inhibition is not obvious.
3rd, the research of vine tea general flavone bacteriostasis:
Experiment uses Beating holes method, determines vine tea general flavone to staphylococcus aureus, Shigella, bacillus subtilis
Bacterium, salmonella, the fungistatic effect of Escherichia coli, and with same test conditions under compound berberine tablet and ospeneff
Fungistatic effect compares.The minimal inhibitory concentration of vine tea general flavone is determined with test tube double dilution method(MIC)It is sterilized with minimum
Concentration(MBC).Result shows, vine tea general flavone to staphylococcus aureus, Shigella, bacillus subtilis, salmonella,
Escherichia coli have fungistatic effect.By comparing the diameter of inhibition zone, vine tea general flavone is to this 5 kinds of fungistatic effects of bacterium
Shigella > salmonella > bacillus subtilis > staphylococcus aureus > Escherichia coli are followed successively by from high to low;For examination
There was only vine tea general flavone in medicine has fungistatic effect to all for examination bacterium, and the 'Compound berberine solution of comparable sodium is to will Hayes
, without inhibition, certain density ospeneff solution on E. coli is without antibacterial effect for bacterium, salmonella and Escherichia coli
Really;It is total that the 'Compound berberine solution of comparable sodium is not so good as vine tea to the fungistatic effect of bacillus subtilis and staphylococcus aureus
Flavones is obvious;Certain density ospeneff solution is not so good as vine tea general flavone to the fungistatic effect of Shigella and salmonella
Substantially, the fungistatic effect to bacillus subtilis and staphylococcus aureus is more much more obvious than vine tea general flavone;By comparing rattan
Tea general flavone understands that vine tea general flavone suppression Shigella is most notable, suppresses Escherichia coli least to 5 kinds of MIC and MBC of bacterium
Significantly.
Claims (4)
1. the whitening anti-inflammatory antibacterial toilet soap of vine tea general flavone is contained, it is characterised in that the whitening anti-inflammatory suppression containing vine tea general flavone
Bacterium perfumed soap calculates be made up of following raw material by weight:1~3 part of palm oil, 5~8 parts of olive oil, 1~3 part of NaOH, water 4
~7 parts, 1~3 part of vine tea general flavone ultrasonic extraction liquid, 0.2~0.5 part of vitamin E, described vine tea general flavone ultrasonic extraction
Liquid is, as raw material, to add 25~35 times to measure the ethanol that volume fraction is 60~80% using vine tea meal, soaks 20~40min
Ultrasonic extraction 1~3 time afterwards, 20~40min, filters and merging filtrate every time, obtains final product vine tea general flavone ultrasonic extraction liquid.
2. the whitening anti-inflammatory antibacterial toilet soap containing vine tea general flavone according to claim 1, it is characterised in that the raw material
Weight portion is:1 part of palm oil, 6 parts of olive oil, 1 part of NaOH, 5 parts of water, 1 part of vine tea general flavone ultrasonic extraction liquid, vitamin
0.3 part of E, described vine tea general flavone ultrasonic extraction liquid is that, used as raw material, 30 times of amount volume fractions of addition are using vine tea meal
70% ethanol, ultrasonic extraction 3 times, each 20min, filter and merging filtrate after immersion 30min, obtain final product vine tea general flavone ultrasound
Extract solution.
3. the preparation method of the whitening anti-inflammatory antibacterial toilet soap of vine tea general flavone is contained as claimed in claim 1 or 2, and its feature exists
In comprising the following steps:
Step one:Palm oil and olive oil are weighed by required weight, is put into container together, heated, fully mixed, and keep temperature
45 DEG C of degree, obtains miscella;
Step 2:Water and NaOH are weighed by required weight, NaOH is slowly added in water, side edged is stirred with alkaline-resisting
Mix device quickly to stir, NaOH is cooled to 45 DEG C after being dissolved completely in water, obtains aqueous slkali;
Step 3:Above-mentioned aqueous slkali is blown slowly in the container for pouring into dress miscella, leaned to one side while quickly being stirred with alkaline-resisting agitator
Mix, obtain soap lye;
Step 4:Ceaselessly stir, untill soap lye surface can mark 8 complete words, obtain thick soap lye;
Step 5:Adding vine tea general flavone ultrasonic extraction liquid and vitamin E while stirring in thick soap lye must mix soap lye;
Step 6:A small amount of olive oil is dipped in mould inside brush time with brush, and the mixing soap lye that step 5 is obtained is poured into mould,
Mould is covered with plastic sheeting again, is placed 1~2 day in 35 DEG C of incubators, obtain perfumed soap;
Step 7:Perfumed soap is removed from the molds, is placed at shady and cool ventilation, placed for 4 to 8 weeks, obtain perfumed soap finished product.
4. application of the vine tea in cosmetic skincare product is prepared.
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Cited By (7)
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CN108992383A (en) * | 2018-10-17 | 2018-12-14 | 武汉市卉研生物科技有限公司 | Vine tea flavone composition alcohol plastid and its preparation method and application |
CN111388367A (en) * | 2020-03-25 | 2020-07-10 | 江南大学 | Composition for inhibiting melanin at multiple target points, preparation method and application of composition in cosmetics |
CN111388367B (en) * | 2020-03-25 | 2021-09-24 | 江南大学 | Composition for inhibiting melanin at multiple target points, preparation method and application of composition in cosmetics |
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