CN106806247A - A kind of skin cream containing red pomegranate gadol extract and preparation method thereof - Google Patents

A kind of skin cream containing red pomegranate gadol extract and preparation method thereof Download PDF

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Publication number
CN106806247A
CN106806247A CN201610932423.6A CN201610932423A CN106806247A CN 106806247 A CN106806247 A CN 106806247A CN 201610932423 A CN201610932423 A CN 201610932423A CN 106806247 A CN106806247 A CN 106806247A
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extract
red pomegranate
phases
red
skin cream
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田鹏新
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Abstract

The present invention relates to a kind of skin cream, more particularly to red pomegranate gadol extract skin cream and preparation method thereof.It includes following components:A phases:Ceteareth 21 0.1 5%, cetostearyl alcohol 1 5%, caprylic/capric triglyceride 5 15%, dimethyl silicone polymer 0.1 5%, cetyl dimethicone 0.1 2%, liposomes vitamin e1 10%;B phases:The dipropylene glycol 1 10% of shea butter 5 15%;The assistant for emulsifying agent 1 5% of isoflavones 0.1 5%;C phases:The red pomegranate gadol extract 3 15% of thickener 1 10%.Remaining material is deionized water.By using red pomegranate gadol extract, and it is equipped with various effective ingredients, overcome the defect that active ingredient is more easily damaged when red pomegranate gadol extract is difficult to be absorbed and be made skin cream in the prior art, improve red pomegranate gadol extract decentralization in skin cream, and obtained skin cream is stable in properties, can give full play to moisturizing, whitening, crease-resistant function.

Description

A kind of skin cream containing red pomegranate-gadol extract and preparation method thereof
Technical field
The present invention relates to a kind of skin cream, more particularly to red pomegranate-gadol extract skin cream and preparation method thereof.
Background technology
With the development in epoch, especially urban woman is most in sealing and air conditioner surroundings and more for modern female Ground is in radiation environment as in the environment of computer screen.It refers to just electromagnetic radiation that computer radiation is main, and electromagnetic radiation is usual With fuel factor, non-thermal effect and stimulation produce biological agent to body.Computer comes to the hidden danger of human health from emission types See, the main electromagnetic radiation (various electromagnetic radiations and electromagnetic wave etc.) for operationally being produced including computer and being sent, sound (noise), Various radiation " pollution " such as light (ultraviolet, infrared radiation and visible ray etc.), Long Term Contact electromagnetic radiation can produce skin Give birth to early ageing, the negative effect such as spot occur;And during the dehumidifier of air-conditioning so that body water is constantly evaporated, even if by mending Fill drinking-water, it is also difficult to even if making up the loss of moisture of skin.Therefore, dry skin and mistake are exposed to radiation environment for a long time, into For the main skin health that most women face in daily life is threatened.
At home and abroad cosmetic field, it is crease-resistant and whitening type skin care item to pay close attention at present more, and for being applicable In daily skin radiation-preventing and dry then less, although sun screen has certain obstruct to make for the negative effect of external environment condition With, but sun screen when mostly more stimulating the dense chemicals modulation of smell form, commonly using being unfavorable for human skin Natural health.Therefore on the premise of product functionality is ensured, consumer more has a mind to purchase addition natural material, instead of artificial Synthesize the cosmetics of chemical composition.
The content of the invention
The present invention and is equipped with various effective ingredients by using red pomegranate-gadol extract, is prepared into red pomegranate-red Red-spotted stonecrop extract skin cream, can overcome red pomegranate-gadol extract to be in the prior art difficult to be absorbed and be made skin cream When the defect that is more easily damaged of active ingredient, improve red pomegranate-gadol extract decentralization in skin cream, and obtained profit Skin frost is stable in properties, can give full play to moisturizing, whitening, crease-resistant function.
One of the object of the invention is to provide the formula of the red pomegranate-gadol extract skin cream.
The two of the object of the invention are to provide the red pomegranate-gadol extract skin cream preparation method.
A kind of skin cream containing red pomegranate-gadol extract, count by weight percentage, it includes following components:
A phases:
The 0.1-5% cetostearyl alcohols of ceteareth -21 1-5%
Caprylic/capric triglyceride 5-15% dimethyl silicone polymers 0.1-5%
Cetyl dimethicone 0.1-2% liposomes vitamin Es 1-10%
B phases:
Shea butter 5-15% dipropylene glycols 1-10%
Isoflavones 0.1-5% assistant for emulsifying agents 1-5%
C phases:
Thickener 1-10% red pomegranates-gadol extract 3-15%
Described red pomegranate-gadol extract is that content ratio is 1-2 respectively:Red pomegranate extract and the rhodiola root of 3-5 are carried Take the mixed extract of thing;
Remaining material is deionized water.
Used as improvement, the red pomegranate-gadol extract skin cream can also be produced using formula as below:
A phases:
The 0.5-2% cetostearyl alcohols of ceteareth -21 2-4%
Caprylic/capric triglyceride 8-12% dimethyl silicone polymers 1-3%
Cetyl dimethicone 0.8-1.2% liposomes vitamin Es 4-8%
B phases:
Shea butter 8-12% dipropylene glycols 4-7%
Isoflavones 0.5-1.5% assistant for emulsifying agents 2-4%
C phases:
Thickener 4-7% red pomegranates-gadol extract 5-10%
Preservative 0.1-0.5% essence 0.1-0.3%
Described red pomegranate-gadol extract is that content ratio is 1-2 respectively:Red pomegranate extract and the rhodiola root of 3-5 are carried Take the mixed extract of thing;
Remaining material is deionized water.
As a further improvement, described thickener is glycerine polymethacrylates or propane diols;
Described preservative is double(Methylol)In imidazolidinyl urea, methyl hydroxybenzoate, Nipasol one or more Mixture;
Described assistant for emulsifying agent is polyacrylamide/C13-14 isoparaffins/laureth -7.
The preparation method of the red pomegranate-gadol extract skin cream is as follows:
(1)Mix A, B two-phase raw material respectively;
(2)The A phases and B phases in addition to assistant for emulsifying agent are heated respectively to 85-95 DEG C, and maintain 20min to sterilize;
(3)When A, B two-phase are cooled to 70-80 DEG C, after B phases are slowly mixed with A phases in 5-15min, 35-40 DEG C is cooled to And add C phase materials;
(4)Add after deionized water and carry out emulsifying treatment, that is, obtain described red pomegranate-gadol extract moisturizing Frost.
After deionized water is added, carried out by way of homogeneous emulsifying machine is below 40 DEG C with 3000-4500r/min During matter emulsification treatment, the mixing of each component can be made more uniform.
In order that the red pomegranate-gadol extract skin cream is better, following methods can be used, prepare red stone Pomegranate-gadol extract:
(1)Rhodiola root and red pomegranate are cleaned respectively, after drying, carries out pulverization process, obtain fineness for the red scape of 100-200 purposes Its powder and red pomegranate powder;
(2)By rhodiola root powder, red pomegranate powder concentration for the hydrochloric acid solution of 10-15% is extracted, red scape is obtained respectively Its extract solution and red pomegranate extract solution;
(3)Rhodiola extract and red pomegranate extract solution are filtered successively respectively, are cooled down, being stood and centrifugal filtration after, adopt With macroporous resin column to the active ingredient in absorption rhodiola extract and red pomegranate extract solution;
(4)Respectively by step(3)The middle macroreticular resin for having adsorbed active ingredient in rhodiola extract and red pomegranate extract solution, makes After deionized water rinsing 5-15min, concentration carries out gradient parsing to the macroreticular resin for 70%-80% ethanol, mixing The desorbed solution that rhodiola extract and red pomegranate extract solution are extracted, and by mixing desorbed solution by being concentrated to give CE;
(5)Petroleum ether cycling extraction will be added in CE, obtain being mixed with the thin medicinal extract of petroleum ether, then made using revolving method After obtaining the petroleum ether volatilization in thin medicinal extract, absolute ethyl alcohol to thin medicinal extract is added to be completely dissolved, then cooled down successively, settled, Centrifugal filtration and concentration, drying, are obtained red pomegranate-rhodiola root leaf extract.
Contain substantial amounts of OPC in red pomegranate, it has very strong activity in vivo.It is demonstrated experimentally that OPC Green Tea Extract oxidability is 50 times of vitamin E, ascorbic 20 times, can effectively remove free radical unnecessary in vivo, protection Human cell tissue prevents and treats the kind more than 100 such as allergy, cancer, aging disease relevant with free radical from the oxidative damage of free radical Disease, also with reinforcement and protection human body active mass, stabilizing cell membrane and antienzyme activity(Histamine decarboxylase)Etc. biological nature. Additionally, OPC possesses good bioavilability, it is easy to be absorbed by the body;
Because endocrine disturbance, the oxygen radical lacked of proper care and cause are excessive, make internal superoxide dismutase (SOD) not enough, lead Cause excessive oxygen radical that the reaction of oxidation is produced with corium confluent monolayer cells, form substantial amounts of lipofuscin (lipid peroxide), cause Chloasma or cyasma.Contained flavone component can hinder formation and calmness of the pigment in skin corium in rhodiola root, reach To skin whitening and the effect for preventing and treating pigment patch.In addition to flavones, the trace element such as manganese, molybdenum in rhodiola root also can be clear Except oxygen radical and suppression melanin growth.
Specific embodiment
The present invention is specifically described with reference to embodiment, the present invention also can be by other essence without departing from its spirit Or the embodiment of essential feature is realized.Therefore, embodiment below, is merely illustrative, and is not only, Suo You Change in the scope of the invention or in equivalent the scope of the present invention and be included in the invention.
Embodiment 1
A kind of skin cream containing red pomegranate-gadol extract, count by weight percentage, it includes following components:
A phases:
The 0.1-5% cetostearyl alcohols of ceteareth -21 1-5%
Caprylic/capric triglyceride 5-15% dimethyl silicone polymers 0.1-5%
Cetyl dimethicone 0.1-2% liposomes vitamin Es 1-10%
B phases:
Shea butter 5-15% dipropylene glycols 1-10%
Isoflavones 0.1-5% assistant for emulsifying agents 1-5%
C phases:
Thickener 1-10% red pomegranates-gadol extract 3-15%
Described red pomegranate-gadol extract is commercially available red pomegranate extract and gadol extract by 2:3 ratio is mixed Conjunction is formed;
Remaining material is deionized water.
The preparation method of the red pomegranate-gadol extract skin cream is as follows:
(1)Mix A, B two-phase raw material respectively;
(2)The A phases and B phases in addition to assistant for emulsifying agent are heated respectively to 85-95 DEG C, and maintain 20min to sterilize;
(3)When A, B two-phase are cooled to 70-80 DEG C, after B phases are slowly mixed with A phases in 5-15min, 35-40 DEG C is cooled to And add C phase materials;
(4)Add after deionized water and carry out emulsifying treatment, that is, obtain described red pomegranate-gadol extract moisturizing Frost.
Embodiment 2
Used as improvement, the red pomegranate-gadol extract skin cream can also be produced using formula as below:
A phases:
The 0.5-2% cetostearyl alcohols of ceteareth -21 2-4%
Caprylic/capric triglyceride 8-12% dimethyl silicone polymers 1-3%
Cetyl dimethicone 0.8-1.2% liposomes vitamin Es 4-8%
B phases:
Shea butter 8-12% dipropylene glycols 4-7%
Isoflavones 0.5-1.5% polyacrylamides 1-2%
The 1-2% of laureth -7
C phases:
Glycerine polymethacrylates 4-7% red pomegranates-gadol extract 5-10%
It is double(Methylol)Imidazolidinyl urea 0.1-0.5% essence 0.1-0.3%
Remaining material is deionized water.
In the present embodiment, red pomegranate-gadol extract is produced in the following manner:
(1)Rhodiola root and red pomegranate are cleaned respectively, after drying, carries out pulverization process, obtain fineness for the red scape of 100-150 purposes Its powder and red pomegranate powder;
(2)Rhodiola root powder, the hydrochloric acid solution that red pomegranate powder concentration is 10% are extracted, rhodiola root is obtained respectively Extract solution and red pomegranate extract solution;
(3)Rhodiola extract and red pomegranate extract solution are filtered successively respectively, are cooled down, being stood and centrifugal filtration after, adopt With macroporous resin column to the active ingredient in absorption rhodiola extract and red pomegranate extract solution;
(4)Respectively by step(3)The middle macroreticular resin for having adsorbed active ingredient in rhodiola extract and red pomegranate extract solution, makes After deionized water rinsing 8min, concentration carries out gradient parsing to the macroreticular resin for 70% ethanol, and mixing rhodiola root is carried The desorbed solution that liquid and red pomegranate extract solution are extracted is taken, and by mixing desorbed solution by being concentrated to give CE;
(5)Petroleum ether cycling extraction will be added in CE, obtain being mixed with the thin medicinal extract of petroleum ether, then made using revolving method After obtaining the petroleum ether volatilization in thin medicinal extract, absolute ethyl alcohol to thin medicinal extract is added to be completely dissolved, then cooled down successively, settled, Centrifugal filtration and concentration, drying, are obtained red pomegranate-rhodiola root leaf extract.
The preparation method of the red pomegranate-gadol extract skin cream is as follows:
(1)Mix A, B two-phase raw material respectively;
(2)The A phases and B phases in addition to assistant for emulsifying agent are heated respectively to 85 DEG C, and maintain 20min to sterilize;
(3)When A, B two-phase are cooled to 75 DEG C, after B phases are slowly mixed with A phases in 15min, it is cooled to 36 DEG C and adds C Phase material;
(4)After adding deionized water, carried out at emulsifying by way of homogeneous emulsifying machine is below 40 DEG C with 3000r/min Reason, that is, obtain described red pomegranate-gadol extract skin cream.
Embodiment 3
In order that the red pomegranate-gadol extract skin cream is better, following methods, preparation red pomegranate-red can be used Red-spotted stonecrop extract:
Embodiment 2
Used as improvement, the red pomegranate-gadol extract skin cream can also be produced using formula as below:
A phases:
The 0.8-1.5% cetostearyl alcohols of ceteareth -21 2.5-4%
Caprylic/capric triglyceride 8-10.5% dimethyl silicone polymers 1-2.5%
Cetyl dimethicone 0.8-1.0% liposomes vitamin Es 5-7%
B phases:
Shea butter 8-10% dipropylene glycols 4-6%
Isoflavones 0.5-1.5% polyacrylamides 1-2%
The 1-2% of laureth -7
C phases:
Glycerine polymethacrylates 4-6.5% red pomegranates-gadol extract 5-8%
It is double(Methylol)Imidazolidinyl urea 0.1-0.5% essence 0.1-0.3%
Remaining material is deionized water.
In the present embodiment, red pomegranate-gadol extract is produced in the following manner:
(1)Rhodiola root and red pomegranate are cleaned respectively, after drying, carries out pulverization process, obtain fineness for the red scape of 150-200 purposes Its powder and red pomegranate powder;
(2)Rhodiola root powder, the hydrochloric acid solution that red pomegranate powder concentration is 15% are extracted, rhodiola root is obtained respectively Extract solution and red pomegranate extract solution;
(3)Rhodiola extract and red pomegranate extract solution are filtered successively respectively, are cooled down, being stood and centrifugal filtration after, adopt With macroporous resin column to the active ingredient in absorption rhodiola extract and red pomegranate extract solution;
(4)Respectively by step(3)The middle macroreticular resin for having adsorbed active ingredient in rhodiola extract and red pomegranate extract solution, makes After deionized water rinsing 15min, concentration carries out gradient parsing to the macroreticular resin for 80% ethanol, mixes rhodiola root The desorbed solution that extract solution and red pomegranate extract solution are extracted, and by mixing desorbed solution by being concentrated to give CE;
(5)Petroleum ether cycling extraction will be added in CE, obtain being mixed with the thin medicinal extract of petroleum ether, then made using revolving method After obtaining the petroleum ether volatilization in thin medicinal extract, absolute ethyl alcohol to thin medicinal extract is added to be completely dissolved, then cooled down successively, settled, Centrifugal filtration and concentration, drying, are obtained red pomegranate-rhodiola root leaf extract.
The preparation method of the red pomegranate-gadol extract skin cream is as follows:
(1)Mix A, B two-phase raw material respectively;
(2)The A phases and B phases in addition to assistant for emulsifying agent are heated respectively to 90 DEG C, and maintain 20min to sterilize;
(3)When A, B two-phase are cooled to 70-80 DEG C, after B phases are slowly mixed with A phases in 10min, it is cooled to 38 DEG C and adds Enter C phase materials;
(4)Add after deionized water and carry out emulsifying treatment, that is, obtain described red pomegranate-gadol extract moisturizing Frost.
After deionized water is added, homogenized milk is carried out by way of homogeneous emulsifying machine is below 40 DEG C with 4500r/min When changing treatment, that is, obtain described red pomegranate-gadol extract skin cream.
The above, the only present invention preferably specific embodiment, but protection scope of the present invention is not limited thereto, Any one skilled in the art the invention discloses technical scope in, the change or replacement that can be readily occurred in, Should all be included within the scope of the present invention.Therefore, protection scope of the present invention should be with scope of the claims It is defined.

Claims (6)

1. a kind of skin cream containing red pomegranate-gadol extract, count by weight percentage, it includes following components:
A phases:
The 0.1-5% cetostearyl alcohols of ceteareth -21 1-5%
Caprylic/capric triglyceride 5-15% dimethyl silicone polymers 0.1-5%
Cetyl dimethicone 0.1-2% liposomes vitamin Es 1-10%
B phases:
Shea butter 5-15% dipropylene glycols 1-10%
Isoflavones 0.1-5% assistant for emulsifying agents 1-5%
C phases:
Thickener 1-10% red pomegranates-gadol extract 3-15%
Described red pomegranate-gadol extract is that content ratio is 1-2 respectively:Red pomegranate extract and the rhodiola root of 3-5 are carried Take the mixed extract of thing;
Remaining material is deionized water.
2. a kind of skin cream containing red pomegranate-gadol extract as claimed in claim 1, count by weight percentage, its Comprising following components:
A phases:
The 0.5-2% cetostearyl alcohols of ceteareth -21 2-4%
Caprylic/capric triglyceride 8-12% dimethyl silicone polymers 1-3%
Cetyl dimethicone 0.8-1.2% liposomes vitamin Es 4-8%
B phases:
Shea butter 8-12% dipropylene glycols 4-7%
Isoflavones 0.5-1.5% assistant for emulsifying agents 2-4%
C phases:
Thickener 4-7% red pomegranates-gadol extract 5-10%
Preservative 0.1-0.5% essence 0.1-0.3%
Described red pomegranate-gadol extract is that content ratio is 1-2 respectively:Red pomegranate extract and the rhodiola root of 3-5 are carried Take the mixed extract of thing;
Remaining material is deionized water.
3. a kind of skin cream containing red pomegranate-gadol extract as claimed in claim 1 or 2, it is characterised in that:
Described thickener is glycerine polymethacrylates or propane diols;
A kind of skin cream containing red pomegranate-gadol extract as claimed in claim 1 or 2, it is characterised in that:
Described preservative is double(Methylol)In imidazolidinyl urea, methyl hydroxybenzoate, Nipasol one or more Mixture;
A kind of skin cream containing red pomegranate-gadol extract as claimed in claim 1 or 2, it is characterised in that:
Described assistant for emulsifying agent is polyacrylamide/C13-14 isoparaffins/laureth -7.
4. the preparation side of a kind of skin cream containing red pomegranate-gadol extract as described in claim 1-5 any one Method, it is characterised in that following steps:
(1)Mix A, B two-phase raw material respectively;
(2)The A phases and B phases in addition to assistant for emulsifying agent are heated respectively to 85-95 DEG C, and maintain 20min to sterilize;
(3)When A, B two-phase are cooled to 70-80 DEG C, after B phases are slowly mixed with A phases in 5-15min, 35-40 DEG C is cooled to And add C phase materials;
(4)Add after deionized water and carry out emulsifying treatment, that is, obtain described red pomegranate-gadol extract moisturizing Frost.
5. the preparation method of a kind of skin cream containing red pomegranate-gadol extract as described in claim 6 any one, It is characterized in that following steps:
Described step(4)In, pass through homogeneous emulsifying machine below 40 DEG C with 3000-4500r/min's after adding deionized water Mode carries out emulsifying treatment.
6. the preparation method of a kind of skin cream containing red pomegranate-gadol extract as described in claim 6 any one, It is characterized in that following steps:
The preparation method of described red pomegranate-gadol extract is as follows:
(1)Rhodiola root and red pomegranate are cleaned respectively, after drying, carries out pulverization process, obtain fineness for the red scape of 100-200 purposes Its powder and red pomegranate powder;
(2)By rhodiola root powder, red pomegranate powder concentration for the hydrochloric acid solution of 10-15% is extracted, red scape is obtained respectively Its extract solution and red pomegranate extract solution;
(3)Rhodiola extract and red pomegranate extract solution are filtered successively respectively, are cooled down, being stood and centrifugal filtration after, adopt With macroporous resin column to the active ingredient in absorption rhodiola extract and red pomegranate extract solution;
(4)Respectively by step(3)The middle macroreticular resin for having adsorbed active ingredient in rhodiola extract and red pomegranate extract solution, makes After deionized water rinsing 5-15min, concentration carries out gradient parsing to the macroreticular resin for 70%-80% ethanol, mixing The desorbed solution that rhodiola extract and red pomegranate extract solution are extracted, and by mixing desorbed solution by being concentrated to give CE;
(5)Petroleum ether cycling extraction will be added in CE, obtain being mixed with the thin medicinal extract of petroleum ether, then made using revolving method After obtaining the petroleum ether volatilization in thin medicinal extract, absolute ethyl alcohol to thin medicinal extract is added to be completely dissolved, then cooled down successively, settled, Centrifugal filtration and concentration, drying, are obtained red pomegranate-rhodiola root leaf extract.
CN201610932423.6A 2016-11-01 2016-11-01 A kind of skin cream containing red pomegranate gadol extract and preparation method thereof Pending CN106806247A (en)

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CN103446195A (en) * 2013-08-22 2013-12-18 陕西洋县志建药业科技有限公司 Preparation method of ginkgo biloba extract
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