CN106798863A

CN106798863A - The medicine of adenovirus pneumonia

Info

Publication number: CN106798863A
Application number: CN201710199334.XA
Authority: CN
Inventors: 卢仁华
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-03-29
Filing date: 2017-03-29
Publication date: 2017-06-06

Abstract

The invention discloses the medicine of adenovirus pneumonia, pharmaceutical technology field, the correct pathological analysis and medicine of adenovirus pneumonia are solved the problems, such as, the Chinese medicine composition taken is applied to therapeutic effect significantly, it is characterized in that being combined by following each traditional Chinese medicine quality ratio：15 parts of spina gleditsiae, 15 parts of the root bark of white mulberry, 15 parts of the dried rhizome of rehmannia, 10 parts of honeysuckle, 15 parts of scorpio, 10 parts of the root bark of tree peony, 10 parts of Fructus Hordei Germinatus, 10 parts of chrysanthemum, 10 parts of mustard seed, 15 parts of the root of large-flowered skullcap, 10 parts of sealwort, 10 parts of the fruit of Chinese wolfberry, 15 parts of the capsule of weeping forsythia, 15 parts of tendril-leaved fritillary bulb, 10 parts of Radix Glycyrrhizae.

Description

The medicine of adenovirus pneumonia

Technical field

The present invention relates to one group of medicine for the treatment of adenovirus pneumonia, belong to medicine technology field.

Background technology

Adenovirus can also be led to infantile pneumonia in addition to the infection of the upper respiratory tract is caused, and be more common in the infant of 6 months to 2 years old Adenovirus pneumonia is the most critical, especially common with northern each province, and the person of being in a bad way is also more southern for many.

Adenovirus typically passes through respiratory tract infection.Often there is adenovirus upper respiratory tract sense simultaneously in collective children mechanism Dye and pneumonia.Crowd's serological research illustrates that initially the several months often retains the adenovirus specific antibody from parent transmission after life, hereafter Until 2 years old antibody deficiency, just gradually increases for 2 years old later.There is facing in 7~24 months infants with adenovirus pneumonia 80% in this Bed observation is complied fully with.

Adenovirus typically passes through respiratory tract infection.It is worth noting that local each age group Susceptible population quantity is more, hair The number of raw adenovirus respiratory tract infection is just more, and the chance that infant occurs adenovirus pneumonia is also bigger.Adenovirus pneumonia exists Northern China is more common in winter and spring, and summer, autumn are only accidental, and the high prevalence in Guangzhou is then more common in autumn in year.This parapneumonia exists Beijing accounts for the 20%~30% of viral pneumonia.

Known adenovirus has 41 Serotypes, wherein much closely relevant with the upper and lower respiratory tract infection of the mankind.From China The Pathogeny Observation of the northern sick child that is in hospital with southern various regions, proves that 3 types and 7 type adenovirus are the main disease of adenovirus pneumonia It is former.From throat swab, excrement or after death lung tissue can isolate virus, convalescent serum antibody titer relatively early stage（Morbidity 5~10 It or earlier）Rise more than 4 times.In the several cases of a part of measles complicated pneumonia, same etiological examination knot is also obtained Really.The ground such as Beijing also found that 11 type adenovirus are also the more typical cause of disease of pneumonia and the infection of the upper respiratory tract（Institute of pediatrics, 1964~1966）.Additionally, 21,14 and 1,2,5,6 etc. types also engender in China's Mainland, Taiwan is then with 1,2,5,6 types It is main.3, the 7 type adenovirus that nearest Bethune medical university to 1976~1988 years separate, have carried out the analysis of genome type, it was demonstrated that 7b Cause severe pneumonia more.

Adenovirus is DNA virus, is mainly bred in nucleus, and heatproof, the ability of acidproof, resistance to fatsolvent are stronger, except pharynx, knot Close outside film and lymphoid tissue, also bred in enteron aisle.3 groups can be divided into according to its agglutinability to special animal erythrocyte, easily Cause 3,7,11,14, the 21 of infantile pneumonia this group, can aggegation monkey red blood cells.

Adenovirus pneumonia is Focal or amalgamation gangrenosum acne lung infiltrates and bronchitis is this sick major lesions.Pneumonia realification The whole of a leaf can be occupied, it is most common with lobe of left lung.On lung tangent plane yellow-white sphacelus composition is can extrude out from realification area Cast sample thing, has obvious wind-puff the lung tissue beyond realification more.Microscopy finding lesion, with bronchitis and peribronchitis Centered on, inflammation often enters to transform into necrosis, and exudate is full of whole tube chamber, also often has exudate in the alveolar space of peribronchial, It is mostly lymph, monocyte, slurries, cellulose, sometimes with bleeding, and neutrocyte is then little, and alveolar wall is also common Necrosis.The visible bronchus in edge or alveolar proliferation of areas of inflammation, Chang Kejian in hyperplasia and in the epithelial nucleus of enlargement Intranuclear inclusion, the approximate normocyte of its size, boundary is clear, dyes inclined acidophilia or thermophilic dichromatism, there is one saturating around it Bright circle；Nuclear membrane understands have a small amount of chromatin to pile up in nuclear membrane inner face；But without inclusion body in endochylema, also without multinucleate giant cell shape Into, therefore, can be distinguished with measles pneumonia and pulmonary type cytomegalic inclusion disease on morphology.Additionally, each internal organs of whole body are such as Central nervous system and heart have interstitial inflammation and thin vessels parietal cell proliferation response.

The treatment of adenovirus pneumonia.1. antiviral treatment：Adenovirus pneumonia, collunarium effect are treated with ribavirin It is unobvious；Use vein and/or intramuscular injection instead, in early-stage cases compared with control group for excellent, late case then DeGrain；Neulized inhalation The research for the treatment of has pending.2. the preventing and treating of secondary bacterial infection.As tentatively concluded there is scabies secondary infection to answer active treatment, for example Infection of staphylococcus aureus new penicillin, cephaloridnum etc.；Escherichia coli aminobenzylpenicillin etc. is treated.3. chlorine third The calmness such as piperazine, fenazil, spasmolysis, cough-relieving are breathed heavily.

The content of the invention

Adenovirus pneumonia, patient often shows spleen and transports weak, reaction sensitivity.With traditional Chinese medicine viewpoint analysis adenovirus pneumonia, category In spleen and lung weakness, wind toxin mouthful enters, and accumulates and invests lung, and wind-heat closes hair, and treatment should be drawn out pus by applying a plaster to the affected part with invigorating the spleen to clear away damp pathogen, heat-clearing, among dispelling wind cool blood Medicine is controlled in medicine combination.

The medicine of adenovirus pneumonia is combined by following each traditional Chinese medicine quality ratio：15 parts of spina gleditsiae, the root bark of white mulberry 15 Part, 15 parts of the dried rhizome of rehmannia, 10 parts of honeysuckle, 15 parts of scorpio, 10 parts of the root bark of tree peony, 10 parts of Fructus Hordei Germinatus, 10 parts of chrysanthemum, 10 parts of mustard seed, the root of large-flowered skullcap 15 Part, 10 parts of sealwort, 10 parts of the fruit of Chinese wolfberry, 15 parts of the capsule of weeping forsythia, 15 parts of tendril-leaved fritillary bulb, 10 parts of Radix Glycyrrhizae.

Property of medicine effect of each traditional Chinese medicine ingredients in the medicine of lower surface analysis adenovirus pneumonia.Spina gleditsiae effect dissipation carbuncle Swollen, apocenosis of drawing out pus by applying a plaster to the affected part cures mainly swollen ulcer drug, sick pestilence, tinea sore etc..Root bark of white mulberry removing heat from lung and relieving asthma, line water detumescence；Dyspnea and cough due to lung-heat is controlled, is spitted blood, Oedema, tinea pedis, difficult urination.Dried rhizome of rehmannia clearing heat and promoting fluid, cool blood, hemostasis, for consumption of YIN caused by febrile disease, the deep red polydipsia of tongue, spot dermexanthesis are told Blood, bleeding from five sense organs or subcutaneous tissue, abscess of throat.Honeysuckle is described as clearing heat and detoxicating good medicine by the traditional Chinese medical science from ancient times, and the stem of honeysuckle, leaf and Huadu can enter Medicine, with removing toxic substances, anti-inflammatory, antivirus, sterilization, diuresis and antipruritic effect.Scorpio is classified as medicine for calming liver and calming endopathic wind, its taste is pungent, mild-natured, It is poisonous, return liver warp, have functions that Inflammation Zhijing, remove obstruction in channels to relieve pain, detoxicating and resolving a mass.The root bark of tree peony thoughts of returning home, clearing heat and cooling blood, promoting blood circulation Dissipate the stasis of blood, nourishing Yin and falling fire, throat, diuresis, anti-inflammatory, calmness, cooling.Spina gleditsiae have detumescence and apocenosis, the saturating purulence of sterilizing, Search effect of wind, desinsection.Fructus Hordei Germinatus strengthening the spleen and stomach, soothing the liver promoting the circulation of qi, for spleen eating less, milk smoulders.Chrysanthemum effect, with scattered It is the effect of wind heat-clearing, flat liver improving eyesight, dim-sighted for treating anemopyretic cold, dizziness of having a headache, red eye, swell pain, eyes.Mustard seeds has a surname Lung slit phlegm, in sharp temperature, removing toxicity for detumescence, appetite-stimulating indigestion-relieving, middle benefit gas profit gas, improving eyesight profit diaphragm；Phlegm is stagnant, the full vexed, sore of septum pectorale to cure mainly cough The illness such as rotten, cold stomachache, constipation that carbuncle and painful swelling, knowledge are become deaf, gum swells.Root of large-flowered skullcap heat-clearing and damp-drying drug, purging intense heat and detonicating, antiabortive, antioxygen Change, antiviral, antibacterial.Polygonatum tonic, enters spleen, and nourishing Yin and moistening lung, blood-nourishing, embellish lung is quenched one's thirst, and controls deficiency of Yin labor and coughs, Xeropulmonary cough, insufficiency of the spleen weak, few dry of food is quenched one's thirst, deficiency of the kidney soreness and weakness of waist and knees, impotence and seminal emission, and tinnitus mesh is dark, and poliosis is physically weak Win thin, wind favus disease.The fruit of Chinese wolfberry can adjust body's immunity, can effectively suppress tumour growth and cell mutation, with delaying Aging, AFL, regulation blood fat and blood sugar, the effect for promoting the aspects such as hematopoiesis function.The capsule of weeping forsythia is a herb, bitter It is cold, with heat-clearing, removing toxic substances, dissipating bind, the effect of detumescence；It is usually used in treatment warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine Pouring such as closes at the symptom.Tendril-leaved fritillary bulb moistens the lung and relieve the cough resolving sputum and relieving asthma, effect of clearing heat and eliminating phlegm, for heat symptom-complex cough, such as cough due to wind-heat evil, scorching Cough, lung-fire cough.Radix Glycyrrhizae is mild-natured, sweet, return 12 warps；There are removing toxic substances, eliminating the phlegm, analgesic, spasmolysis so that the pharmacological action such as anticancer； In the traditional Chinese medical science, Radix Glycyrrhizae is invigorated the spleen and benefited qi, and moistening lung, emergency removing toxic substances, hundred medicines of mediation are coughed in taste.

The medicine beneficial effect of the invention of adenovirus pneumonia is：The medicine of adenovirus pneumonia is by with traditional Chinese medicine Viewpoint analysis adenovirus pneumonia, belongs to spleen and lung weakness, and wind toxin mouthful enters, accumulates and invest lung, and wind-heat closes hair, takes with invigorating the spleen to clear away damp pathogen, clearly Hot drawing poison, the Chinese medicine combination of dispelling wind cool blood control medicine, and significantly, recurrence rate is few for application effect.

Specific embodiment

It is further described as the presently preferred embodiments with being suitable for adenovirus pneumonia patient's dose below.

The medicine of adenovirus pneumonia is to press suitable for the dosage dose that an adenovirus pneumonia patient takes Each traditional Chinese medicine quality in face is combined：15 grams of spina gleditsiae, 15 grams of the root bark of white mulberry, 15 grams of the dried rhizome of rehmannia, 10 grams of honeysuckle, 15 grams of scorpio, the root bark of tree peony 10 grams, 10 grams of Fructus Hordei Germinatus, 10 grams of chrysanthemum, 10 grams of mustard seed, 15 grams of the root of large-flowered skullcap, 10 grams of sealwort, 10 grams of the fruit of Chinese wolfberry, 15 grams of the capsule of weeping forsythia, tendril-leaved fritillary bulb 15 grams, 10 grams of Radix Glycyrrhizae.

Claims

1. the medicine of adenovirus pneumonia, it is characterized in that being combined by following each traditional Chinese medicine quality ratio：15 parts of spina gleditsiae, Sang Bai 15 parts of skin, 15 parts of the dried rhizome of rehmannia, 10 parts of honeysuckle, 15 parts of scorpio, 10 parts of the root bark of tree peony, 10 parts of Fructus Hordei Germinatus, 10 parts of chrysanthemum, 10 parts of mustard seed, Huang 15 parts of a kind of reed mentioned in ancient books, 10 parts of sealwort, 10 parts of the fruit of Chinese wolfberry, 15 parts of the capsule of weeping forsythia, 15 parts of tendril-leaved fritillary bulb, 10 parts of Radix Glycyrrhizae.