CN106729498A - 一种放化疗后食用的蛋白粉及其制备方法 - Google Patents
一种放化疗后食用的蛋白粉及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种放化疗后食用的蛋白粉及其制备方法，由以下重量份原料制成：半夏0.3‑0.5份、威灵仙0.5‑0.7份、怀山药0.3‑0.5份、玉蝴蝶0.5‑0.8份、生黄芪0.5‑0.8份、茯苓2‑3份、泽泻1‑2份、当归1.2‑1.6份、川穹2‑2.5份、杜仲炭0.4‑0.8份、生姜1‑3份、人参水提取物浸膏粉0.3‑0.5份、灵芝水提取物浸膏粉0.3‑0.5份、银耳粉3‑5份、杏仁粉1‑2份、海藻粉1‑2份、水解乳清蛋白1.5‑2.0份。本发明的蛋白粉，可以减少放化疗引起副作用，有效改善放化疗后肠胃功能，提高放化疗患者免疫力，有治癌和降低放化疗毒副作用双疗效。
Description
技术领域
本发明涉及保健食品技术领域，尤其涉及一种放化疗后食用的蛋白粉及其制备方法。
背景技术
放化疗，是对病原微生物、寄生虫、恶性肿瘤所致得以疾病的药物晋升治疗。化疗也指开始应用药物治疗癌症，这些特殊的药物可杀灭肿瘤细胞，有时称为细胞毒药物。放疗就是放射治疗，指用射线消除病灶，放射治疗作为治疗恶性肿瘤的一个重要手段。化疗是肿瘤合作治疗的一个有效手段，但几乎所有的化疗药物都会引起患者不同程度的食欲不振、恶、呕吐等，从而削弱患者的营养状况，患者会出现周身疲乏无力、精神萎靡、出虚汗、嗜睡等，而且化疗药物会损害患者的免疫系统，导致免疫功能缺陷或下降。如果这时再加用其它药物对放化的毒副作用同时进行治疗，会加重患者精神负担，不利放化的疗效。目前供放化疗患者食用的保健蛋白粉，尚未见报道，它具有抗癌和抗放化毒副作用的双重效应。
发明内容
本发明的目的是克服现有技术的不足，提供一种放化疗后食用的蛋白粉，可以减少放化疗引起的白细胞减少、头昏、失眠、恶心呕吐、食欲减退等副作用，使机体对放化疗的毒性损伤减少，有效改善放化疗后肠胃功能，而且清除有害自由基，提高放化疗患者机体的免疫力，同时预防肿瘤的转移与复发，预防放化疗时出现耐药性，有治癌和降低放化疗毒副作用双疗效。
本发明的另一目的是提供该放化疗后食用的蛋白粉的制备方法。
为了实现上述目的，本发明采用如下技术方案：
一种放化疗后食用的蛋白粉，由以下重量份的原料制成：半夏0.3-0.5份、威灵仙0.5-0.7份、怀山药0.3-0.5份、玉蝴蝶0.5-0.8份、生黄芪0.5-0.8份、茯苓2-3份、泽泻1-2份、当归1.2-1.6份、川穹2-2.5份、杜仲炭0.4-0.8份、生姜1-3份、人参水提取物浸膏粉0.3-0.5份、灵芝水提取物浸膏粉0.3-0.5份、银耳粉3-5份、杏仁粉1-2份、海藻粉1-2份、水解乳清蛋白1.5-2.0份。
所述的人参水提取物浸膏粉由以下方法制备：将人参清洗干净，烘干，碾碎，过40目的筛网收集人参粉末；向人参粉末中加入5倍体积的蒸馏水，加热至液体微沸状态提取1小时，提取液转移至离心机上3500转/分离心10分钟后分离上层提取液，再将人参提取液转移至旋转蒸发仪上减压蒸馏至稠膏状；然后将人参浸膏转移至鼓风干燥箱50℃鼓风干燥24小时，粉碎至微粉，即得人参水提取物浸膏粉。制成浸膏粉形式，药效成分通过口腔粘膜直接被吸收，避免有效成分通过消化系统的吸收而产生的肝脏首过效应，提高药效成分利用率，而且使终产品蛋白粉无药味。
所述的灵芝水提取物浸膏粉由以下方法制备：将灵芝清洗干净，烘干，碾碎，过40目的筛网收集灵芝粉末；向灵芝粉末中加入5倍体积的蒸馏水，加热至液体微沸状态提取1小时，提取液转移至离心机上3500转/分离心10分钟后分离上层提取液，再将灵芝提取液转移至旋转蒸发仪上减压蒸馏至稠膏状；然后将灵芝浸膏转移至鼓风干燥箱50℃鼓风干燥24小时，粉碎至微粉，即得灵芝水提取物浸膏粉。
所述的海藻粉由以下方法制备：先将海藻洗净，放入海藻重量5-6倍的水中浸泡1-2小时，循环浸泡3-4次，然后取出放入海藻重量5-6倍质量比为1-2％的玫瑰花茶溶液中，浸泡10-20分钟；然后取出，用搅碎机捣碎，加入海藻重量2-3倍的水，充分搅匀，用100目筛网过滤得到海藻浆液；最后在温度为80-100℃、压力为50-60Mpa下进行干燥得到海藻粉。海藻中含有植物活性硒，补充植物活性硒可以提高放化疗患者机体的免疫力，使患者机体有足够能力顺利完成放化疗，免疫力的提高也有利于帮助肿瘤患者尽快康复，同时预防肿瘤的转移与复发，能预防放化疗时出现耐药性，有效缓解放化疗引起的白细胞减少及肠胃不适的情况；通过上述方法制备海藻粉，可以大大改变海藻的腥味，使得终产品蛋白粉的口味醇香。
所述的放化疗后食用的蛋白粉的制备方法，其特征在于：包括以下步骤：
(1)将半夏、威灵仙、怀山药、玉蝴蝶、生黄芪、茯苓、泽泻、当归、川穹、杜仲炭、生姜清洗干净，烘干，碾碎，过40目的筛网，混合得中药粉；向中药粉中加入5倍体积的蒸馏水，加热至液体微沸状态提取1小时，提取液转移至离心机上3500转/分钟，离心15分钟后分离上层提取液，得中药提取液；
(2)将步骤(1)的中药提取液与人参水提取物浸膏粉、灵芝水提取物浸膏粉、银耳粉、杏仁粉、海藻粉、水解乳清蛋白搅拌混合均匀；
(3)磨浆：采用胶体磨对步骤(2)的混合物进行磨浆，得磨浆液；
(4)均质：将磨浆液放入均质机中均质，均质机的压强为20-25Mpa，得到均质液；
(5)将均质液进行喷雾干燥，杀菌，包装即可。
本发明用开水冲调后就可以直接食用，方便卫生。
本发明的半夏、威灵仙和生姜配合，具有降肺胃虚逆之气及止呕之功，增强抵抗力，使机体对放化疗的毒性损伤减少，可以改变胃气、减少放化疗对胃粘膜的刺激损伤，有效地治疗放化疗引起的呕吐，可使患者增加食欲；怀山药含有淀粉酶、多酚氧化物等物质，有利于胃消化吸收功能；玉蝴蝶具有润肺、舒肝、和胃、生肌功效；生黄芪具有补气固表，利尿托毒，排脓，生肌功效；茯苓具有调理肠胃，健脾宁心的功效，可以提高机体免疫功能、增强消化吸收能力、促进疾病的治疗和患者康复；泽泻具有利水渗湿，泄热、益气力的功效；当归既能补血，又可活血，可以调经止痛、润燥滑肠；川穹能辛散温通，既能活血化瘀，又能行气止痛，为“血中之气药”，具通达气血功效；杜仲炭可以补肝肾及强筋骨；人参具有补气固脱，健脾益肺，养血生津，宁心益智的功效，主治久病、大病、失血、脱液所致元气欲脱，脾气不足之食少倦怠，肺气虚弱之气短喘促，心气虚衰之失眠多梦，体虚多汗，血虚之萎黄，眩晕，肾虚之阳萎，尿频，气虚外感；灵芝具有增强人体免疫力，调节血糖，控制血压，辅助肿瘤放化疗，保肝护肝，促进睡眠的功效；银耳粉含多糖，可以抗癌，提升白细胞，养胃生津，益气活血，清肺润肠；杏仁粉具有镇咳、平喘、润肠通便、抗炎、镇痛的作用，而且促进肿瘤细胞凋亡。
与已有技术相比，本发明的有益效果如下：
本发明的放化疗后食用的蛋白粉，可以减少放化疗引起的白细胞减少、头昏、失眠、恶心呕吐、食欲减退等副作用，使机体对放化疗的毒性损伤减少，有效改善放化疗后肠胃功能，而且清除有害自由基，提高放化疗患者机体的免疫力，同时预防肿瘤的转移与复发，预防放化疗时出现耐药性，有治癌和降低放化疗毒副作用双疗效，而且口感好，口味醇香，易于患者食用。
具体实施方式
以下结合实施例对本发明作进一步的说明，但本发明不仅限于这些实施例，在未脱离本发明宗旨的前提下，所作的任何改进均落在本发明的保护范围之内。
首先，自市场购买或现有技术获得半夏、威灵仙、怀山药、玉蝴蝶、生黄芪、茯苓、泽泻、当归、川穹、杜仲炭、生姜、人参、灵芝、银耳粉、杏仁粉、海藻、水解乳清蛋白、玫瑰花茶溶液。
接着，按以下方法制备所述的人参水提取物浸膏粉、灵芝水提取物浸膏粉、海藻粉：
将人参清洗干净，烘干，碾碎，过40目的筛网收集人参粉末；向人参粉末中加入5倍体积的蒸馏水，加热至液体微沸状态提取1小时，提取液转移至离心机上3500转/分离心10分钟后分离上层提取液，再将人参提取液转移至旋转蒸发仪上减压蒸馏至稠膏状；然后将人参浸膏转移至鼓风干燥箱50℃鼓风干燥24小时，粉碎至微粉，即得人参水提取物浸膏粉；
将灵芝清洗干净，烘干，碾碎，过40目的筛网收集灵芝粉末；向灵芝粉末中加入5倍体积的蒸馏水，加热至液体微沸状态提取1小时，提取液转移至离心机上3500转/分离心10分钟后分离上层提取液，再将灵芝提取液转移至旋转蒸发仪上减压蒸馏至稠膏状；然后将灵芝浸膏转移至鼓风干燥箱50℃鼓风干燥24小时，粉碎至微粉，即得灵芝水提取物浸膏粉。
将海藻洗净，放入海藻重量5-6倍的水中浸泡1-2小时，循环浸泡3-4次，然后取出放入海藻重量5-6倍质量比为1-2％的玫瑰花茶溶液中，浸泡10-20分钟；然后取出，用搅碎机捣碎，加入海藻重量2-3倍的水，充分搅匀，用100目筛网过滤得到海藻浆液；最后在温度为80-100℃、压力为50-60Mpa下进行干燥得到海藻粉。
然后，
实施例1：
一种放化疗后食用的蛋白粉，由以下重量份的原料制成：半夏0.3份、威灵仙0.7份、怀山药0.3份、玉蝴蝶0.5份、生黄芪0.5份、茯苓3份、泽泻1份、当归1.2份、川穹2份、杜仲炭0.8份、生姜1份、人参水提取物浸膏粉0.3份、灵芝水提取物浸膏粉0.5份、银耳粉3份、杏仁粉2份、海藻粉1份、水解乳清蛋白1.5份。
所述的放化疗后食用的蛋白粉的制备方法，其特征在于：包括以下步骤：
(1)将半夏、威灵仙、怀山药、玉蝴蝶、生黄芪、茯苓、泽泻、当归、川穹、杜仲炭、生姜清洗干净，烘干，碾碎，过40目的筛网，混合得中药粉；向中药粉中加入5倍体积的蒸馏水，加热至液体微沸状态提取1小时，提取液转移至离心机上3500转/分钟，离心15分钟后分离上层提取液，得中药提取液；
(2)将步骤(1)的中药提取液与人参水提取物浸膏粉、灵芝水提取物浸膏粉、银耳粉、杏仁粉、海藻粉、水解乳清蛋白搅拌混合均匀；
(3)磨浆：采用胶体磨对步骤(2)的混合物进行磨浆，得磨浆液；
(4)均质：将磨浆液放入均质机中均质，均质机的压强为20Mpa，得到均质液；
(5)将均质液进行喷雾干燥，杀菌，包装即可。
实施例2：
一种放化疗后食用的蛋白粉，由以下重量份的原料制成：半夏0.4份、威灵仙0.6份、怀山药0.4份、玉蝴蝶0.6份、生黄芪0.6份、茯苓2.2份、泽泻1.9份、当归1.4份、川穹2.1份、杜仲炭0.6份、生姜2份、人参水提取物浸膏粉0.4份、灵芝水提取物浸膏粉0.4份、银耳粉4份、杏仁粉1.5份、海藻粉1.5份、水解乳清蛋白1.8份。
所述的放化疗后食用的蛋白粉的制备方法，其特征在于：包括以下步骤：
(1)将半夏、威灵仙、怀山药、玉蝴蝶、生黄芪、茯苓、泽泻、当归、川穹、杜仲炭、生姜清洗干净，烘干，碾碎，过40目的筛网，混合得中药粉；向中药粉中加入5倍体积的蒸馏水，加热至液体微沸状态提取1小时，提取液转移至离心机上3500转/分钟，离心15分钟后分离上层提取液，得中药提取液；
(2)将步骤(1)的中药提取液与人参水提取物浸膏粉、灵芝水提取物浸膏粉、银耳粉、杏仁粉、海藻粉、水解乳清蛋白搅拌混合均匀；
(3)磨浆：采用胶体磨对步骤(2)的混合物进行磨浆，得磨浆液；
(4)均质：将磨浆液放入均质机中均质，均质机的压强为25Mpa，得到均质液；
(5)将均质液进行喷雾干燥，杀菌，包装即可。
实施例3：
一种放化疗后食用的蛋白粉，由以下重量份的原料制成：半夏0.5份、威灵仙0.5份、怀山药0.5份、玉蝴蝶0.8份、生黄芪0.8份、茯苓3份、泽泻2份、当归1.6份、川穹2.5份、杜仲炭0.4份、生姜3份、人参水提取物浸膏粉0.5份、灵芝水提取物浸膏粉0.3份、银耳粉5份、杏仁粉2份、海藻粉2份、水解乳清蛋白2.0份。
所述的放化疗后食用的蛋白粉的制备方法，其特征在于：包括以下步骤：
(1)将半夏、威灵仙、怀山药、玉蝴蝶、生黄芪、茯苓、泽泻、当归、川穹、杜仲炭、生姜清洗干净，烘干，碾碎，过40目的筛网，混合得中药粉；向中药粉中加入5倍体积的蒸馏水，加热至液体微沸状态提取1小时，提取液转移至离心机上3500转/分钟，离心15分钟后分离上层提取液，得中药提取液；
(2)将步骤(1)的中药提取液与人参水提取物浸膏粉、灵芝水提取物浸膏粉、银耳粉、杏仁粉、海藻粉、水解乳清蛋白搅拌混合均匀；
(3)磨浆：采用胶体磨对步骤(2)的混合物进行磨浆，得磨浆液；
(4)均质：将磨浆液放入均质机中均质，均质机的压强为25Mpa，得到均质液；
(5)将均质液进行喷雾干燥，杀菌，包装即可。
本发明的实际试验病例：
李某，女，55岁，合肥市，患者于2010年4月，出现下腹部疼痛，月经量多，曾到安徽省立医院诊断为宫体癌，给予FD方案化疗，化疗后出现面色萎黄，不思饮食，呕吐恶心，舌质淡白，苔少乏津，脉沉细。食用本发明蛋白粉：早晚一次用开水冲调，一次20ml，一个月后，患者饮食改善，面色红润，呕吐减轻，检测各项指标，达到了临床的好转。
许某，男，60岁，安庆市，在咳嗽，胸痛，少气懒言，检查CT之后，在安徽医科大学第一附属一样，进行活体组织学检查，诊断为肺癌-纵隔淋巴结转移；行CBP方案化疗后2周，气短懒言，身体消瘦，呕吐恶心，舌质淡白，苔花剥，脉细弱。食用本发明蛋白粉：早晚一次用开水冲调，一次20ml，两个月后，患者饮食改善，面色转红，呕吐减轻，检测各项指标，到了临床的好转。
鲁某，女，45岁，铜陵市，2012年患乳腺癌手切后化疗，出现脱发、恶心、乏力、厌食等现象；经使用本发明蛋白粉：早晚一次用开水冲调，一次30ml，一个月后，饮食增加，精神好转，心悸、乏力现象都已消失，脱发症状也得到改善，体质得到改善。
Claims (5)
1.一种放化疗后食用的蛋白粉，其特征在于：由以下重量份的原料制成：半夏0.3-0.5份、威灵仙0.5-0.7份、怀山药0.3-0.5份、玉蝴蝶0.5-0.8份、生黄芪0.5-0.8份、茯苓2-3份、泽泻1-2份、当归1.2-1.6份、川穹2-2.5份、杜仲炭0.4-0.8份、生姜1-3份、人参水提取物浸膏粉0.3-0.5份、灵芝水提取物浸膏粉0.3-0.5份、银耳粉3-5份、杏仁粉1-2份、海藻粉1-2份、水解乳清蛋白1.5-2.0份。
2.根据权利要求1所述的放化疗后食用的蛋白粉，其特征在于：所述的人参水提取物浸膏粉由以下方法制备：将人参清洗干净，烘干，碾碎，过40目的筛网收集人参粉末；向人参粉末中加入5倍体积的蒸馏水，加热至液体微沸状态提取1小时，提取液转移至离心机上3500转/分离心10分钟后分离上层提取液，再将人参提取液转移至旋转蒸发仪上减压蒸馏至稠膏状；然后将人参浸膏转移至鼓风干燥箱50℃鼓风干燥24小时，粉碎至微粉，即得人参水提取物浸膏粉。
3.根据权利要求1所述的放化疗后食用的蛋白粉，其特征在于：所述的灵芝水提取物浸膏粉由以下方法制备：将灵芝清洗干净，烘干，碾碎，过40目的筛网收集灵芝粉末；向灵芝粉末中加入5倍体积的蒸馏水，加热至液体微沸状态提取1小时，提取液转移至离心机上3500转/分离心10分钟后分离上层提取液，再将灵芝提取液转移至旋转蒸发仪上减压蒸馏至稠膏状；然后将灵芝浸膏转移至鼓风干燥箱50℃鼓风干燥24小时，粉碎至微粉，即得灵芝水提取物浸膏粉。
4.根据权利要求1所述的放化疗后食用的蛋白粉，其特征在于：所述的海藻粉由以下方法制备：先将海藻洗净，放入海藻重量5-6倍的水中浸泡1-2小时，循环浸泡3-4次，然后取出放入海藻重量5-6倍质量比为1-2％的玫瑰花茶溶液中，浸泡10-20分钟；然后取出，用搅碎机捣碎，加入海藻重量2-3倍的水，充分搅匀，用100目筛网过滤得到海藻浆液；最后在温度为80-100℃、压力为50-60Mpa下进行干燥得到海藻粉。
5.根据权利要求1-4中任一项所述的放化疗后食用的蛋白粉的制备方法，其特征在于：包括以下步骤：
(1)将半夏、威灵仙、怀山药、玉蝴蝶、生黄芪、茯苓、泽泻、当归、川穹、杜仲炭、生姜清洗干净，烘干，碾碎，过40目的筛网，混合得中药粉；向中药粉中加入5倍体积的蒸馏水，加热至液体微沸状态提取1小时，提取液转移至离心机上3500转/分钟，离心15分钟后分离上层提取液，得中药提取液；
(2)将步骤(1)的中药提取液与人参水提取物浸膏粉、灵芝水提取物浸膏粉、银耳粉、杏仁粉、海藻粉、水解乳清蛋白搅拌混合均匀；
(3)磨浆：采用胶体磨对步骤(2)的混合物进行磨浆，得磨浆液；
(4)均质：将磨浆液放入均质机中均质，均质机的压强为20-25Mpa，得到均质液；
(5)将均质液进行喷雾干燥，杀菌，包装即可。
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| CN110574916A (zh) * | 2018-06-11 | 2019-12-17 | 江苏帝尔生物科技有限公司 | 一种具有减脂和通便功效的营养代餐产品及其制备方法 |
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| CN102068607A (zh) * | 2011-01-05 | 2011-05-25 | 中国人民解放军第三七一医院 | 治疗由放、化疗引起的白细胞减少及肠胃不适的中药制剂 |
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| CN110574916A (zh) * | 2018-06-11 | 2019-12-17 | 江苏帝尔生物科技有限公司 | 一种具有减脂和通便功效的营养代餐产品及其制备方法 |
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