CN106729422A - A kind of raw arteries and veins pulvis curcumae Chinese medicine composition of adjuvant therapy radiotherapy and its application - Google Patents
A kind of raw arteries and veins pulvis curcumae Chinese medicine composition of adjuvant therapy radiotherapy and its application Download PDFInfo
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Abstract
The invention discloses a kind of raw arteries and veins pulvis curcumae Chinese medicine composition of adjuvant therapy radiotherapy and its application, its formula is composed of the following components：The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, the parts by weight of the fruit of Chinese magnoliavine are：3‑12:3‑12:3‑12:2‑12.Raw arteries and veins pulvis curcumae Chinese medicine composition of the invention, both sensitiveness of the tumour cell to radiotherapy ray can have been strengthened, therefore can be combined with Western medicine and tumour radiotherapy, so as to strengthen the curative effect of radiotherapy, the body of patient can be nourished again, and reduce various side effects and adverse reaction caused by radiotherapy, and Chinese medicine used is all integration of drinking and medicinal herbs medicinal material, so its toxic and side effect is smaller, and raw material is simple and easy to get, convenient to take, body and economic pressures to patient all greatly reduce.
Description
Technical field
The present invention relates to a kind of Chinese prescription of adjuvant therapy radiotherapy, and in particular to a kind of Shengmai San plus-minus side is " raw
The Chinese prescription and its preparation of arteries and veins pulvis curcumae " auxiliary enhancing tumour radiotherapy sensitiveness.
Background technology
Malignant tumour is the disease for seriously threatening human health, due to the biological property of tumour cell, and to difference
It is unsatisfactory that the factors such as the sensitiveness of ray, the difference of tolerance often lead to radiotherapy.Although by improving local radiation
Dosage further controls the survival rate of tumour cell, but can cause more serious radioreaction, particularly acute radio-reaction, such as
Dermoreaction, mucosa reaction, parotid gland reaction and more serious general reaction.Chinese medicine is antitumor with Mutiple Targets, and pleiotropism, poison is secondary
The features such as effect is few, therefore in recent years by the increasing research institution's attention that arrives.
The content of the invention
It is an object of the invention to provide a kind of raw arteries and veins pulvis curcumae Chinese medicine composition of adjuvant therapy radiotherapy, can strengthen swollen
Oncocyte reduces various side effects and adverse reaction caused by radiotherapy to the sensitiveness of radiotherapy ray.
Another object of the present invention is to be applied to above-mentioned raw arteries and veins pulvis curcumae Chinese medicine composition to prepare adjuvant therapy radiation
The medicine for the treatment of, is combined so as to strengthen the curative effect of radiotherapy with Western medicine and tumour radiotherapy.
The object of the present invention is achieved like this：A kind of raw arteries and veins pulvis curcumae Chinese medicine composition of adjuvant therapy radiotherapy,
It is characterized in that：Formula is composed of the following components：The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, the parts by weight of the fruit of Chinese magnoliavine are：3-12:3-
12:3-12:2-12。
Preferably, it is formulated composed of the following components：The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, the parts by weight of the fruit of Chinese magnoliavine are：3-9:
3-9:3-9:2-9。
It is furthermore preferred that formula is composed of the following components：The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, the parts by weight of the fruit of Chinese magnoliavine are：3-
6:3-6:3-6:2-6。
Above-mentioned raw arteries and veins pulvis curcumae Chinese medicine composition is applied to prepare the medicine of adjuvant therapy radiotherapy.
Described tumour is nasopharyngeal carcinoma.
The preparation method of the medicine is comprised the following steps：(1) ginseng, turmeric, the tuber of dwarf lilyturf, the fruit of Chinese magnoliavine, powder are weighed by formula
It is broken；(2) turmeric is extracted 2-3 times with 40%-95% alcohol refluxs, ginseng, the tuber of dwarf lilyturf, fruit of Chinese magnoliavine water boiling and extraction 2-3 times, every time
Plus alcohol or water are 5-15 times, each refluxing extraction 1-3 hours of medicinal material amount；Or, ginseng, the tuber of dwarf lilyturf, the fruit of Chinese magnoliavine, turmeric decocting
Extraction 2-3 times is boiled, the amount for adding water every time is 5-15 times of medicinal material and measures, and boils extraction 1-3 hours；(3) merge extract solution and cross filtration
Hair is concentrated to relative density for 1.10/80 DEG C -1.30/80 DEG C, obtains medicinal material extract medicinal extract；(4) corresponding pharmaceutic adjuvant is added to mix
Close, preparation is made by the technique of corresponding formulation.
The formulation of described medicine is decoction, pill, powder, paste, sublimed preparation, vina, syrup, extract, lozenge, dew
Agent, jelly, medicinal tea, nail agent, stylus, suppository, herbal leaven, paste, cake agent, liniment, finish are washed, line agent, medicated roll, agent is pressed, is processed agent, cigarette
Agent, medicine perfume (or spice) etc., tablet, electuary, bagged instant preparation, oral solutions, capsule, pill, mixture, tincture, aerosol, enema, film
Agent, eye-drops preparations, nasal formulations, sponginum or injection.
The formulation of described medicine is peroral dosage form.
Raw arteries and veins pulvis curcumae Chinese medicine composition of the invention, can both strengthen sensitiveness of the tumour cell to radiotherapy ray, therefore
Can be combined with Western medicine and tumour radiotherapy, so as to strengthen the curative effect of radiotherapy, the body of patient can be nourished again, and subtract
Various side effects and adverse reaction caused by few radiotherapy, and Chinese medicine used is all integration of drinking and medicinal herbs medicinal material, so its poison is secondary make
With smaller, and raw material is simple and easy to get, and convenient to take, body and economic pressures to patient all greatly reduce.
Brief description of the drawings
Fig. 1 is the influence of the Shengmai San and raw arteries and veins pulvis curcumae of various concentrations to the radiosensitivity of nasopharyngeal carcinoma cell CNE-2；
Fig. 2 is the influence of the Shengmai San and raw arteries and veins pulvis curcumae of various concentrations to people's immortalization nasopharyngeal cells NP69 cells.
Specific embodiment
The present invention is a kind of raw arteries and veins pulvis curcumae Chinese medicine composition of adjuvant therapy radiotherapy, it is characterised in that：Formula by
Following components is constituted：The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, the parts by weight of the fruit of Chinese magnoliavine are：3-12:3-12:3-12:2-12.It is preferred that
, it is formulated composed of the following components：The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, the parts by weight of the fruit of Chinese magnoliavine are：3-9:3-9:3-9:2-9.
It is furthermore preferred that formula is composed of the following components：The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, the parts by weight of the fruit of Chinese magnoliavine are：3-6:3-6:3-
6:2-6。
Above-mentioned raw arteries and veins pulvis curcumae Chinese medicine composition is applied to prepare the medicine of adjuvant therapy (especially nasopharyngeal carcinoma) radiotherapy
Thing.
The preparation method of described medicine is comprised the following steps：The preparation method of the medicine is comprised the following steps：(1) press
Formula weighs ginseng, turmeric, the tuber of dwarf lilyturf, the fruit of Chinese magnoliavine, crushes；(2) turmeric is extracted 2-3 times with 40%-95% alcohol refluxs, ginseng,
The tuber of dwarf lilyturf, fruit of Chinese magnoliavine water boiling and extraction 2-3 times, every time plus alcohol or water are 5-15 times of medicinal material amount, each refluxing extraction 1-3 is small
When；Or, ginseng, the tuber of dwarf lilyturf, the fruit of Chinese magnoliavine, turmeric water boiling and extraction 2-3 times, the amount for adding water every time is measured for 5-15 times of medicinal material,
Boil extraction 1-3 hours；(3) merge extract solution filtering to be concentrated by evaporation to relative density is 1.10/80 DEG C -1.30/80 DEG C, obtains medicine
Material extracts medicinal extract；(4) corresponding pharmaceutic adjuvant mixing is added, preparation is made by the technique of corresponding formulation.
Allow the auxiliary material for adding to mix with country and professional standard and regulation above-mentioned medicinal extract, medicine is made by proper method
Any formulation of product, for example：Decoction, pill (honeyed bolus, the water-bindered pill, starched pill, wax-wrapped pill, condensed pill), powder, paste (cream taste, ointment,
Plaster), sublimed preparation, vina, syrup, extract, lozenge, distillate medicinal water, jelly, medicinal tea, nail agent, stylus, suppository, herbal leaven, paste, cake
Agent, wash liniment, finish, line agent (medicated thread), medicated roll (fuse), press agent, process agent, fumicants, medicine perfume (or spice) etc., tablet, electuary, bagged instant preparation,
Oral solutions, capsule, pill, mixture, tincture, aerosol, enema, film (membrane agent), eye-drops preparations (eyewash,
Eye drops, ophthalmic ointment), nasal formulations (nasal drop, nasal spray), sponginum (sterilizing hemostasis), the formulation such as injection.The present invention is excellent
First select the formulations such as peroral dosage form, such as soft extract, tablet, capsule, vina, medicinal tea, electuary, bagged instant preparation, mixture.
The present invention is to carry out plus-minus side on the basis of traditional herbal medicine Shengmai San to form.Shengmai San is traditional Chinese medicine simply,
It is earliest that the Tang Dynasty holy doctor SUN Si miao is proposed.Red ginseng tonifying lung gas, nourishing generate fluid in side in Shengmai San, are monarch drug in a prescription；The tuber of dwarf lilyturf is supported
Yin and clearing lung-heat and promote the production of body fluid, be ministerial drug；The fruit of Chinese magnoliavine is astringeed the lung to stop cough, hidroschesis, is adjutant.Three taste medicines are shared, altogether into invigorating the lung and benefiting vital QI, yin-nourishing life
The work(in Tianjin.For QIYINLIANGXU, palpitation, weak pulse spontaneous perspiration.
Ginseng：The root of Araliaceae (Araliaceae) plant ginseng.Property sweet, slight bitter, tepor.Enter spleen, lung channel.Big complement
Gas, Gu de- promote the production of body fluid, calms the nerves.Control internal lesion caused by overexertion deficient, food is told in deficiency of food, burnout, gastric disorder causing nausea, lingering diarrhea of defecating, empty cough and asthma promotees, and spontaneous perspiration takes off cruelly, shies
Throb with fear, forgetful, dizziness and headache, impotence, frequent micturition is quenched one's thirst, and woman uterine bleeding, children shy slowly, and it is empty long not multiple, all qi-blood-body fluids are not enough
Card.
Turmeric：The dry rhizome of zingiberaceous plant turmeric (Curcuma longa L.).Taste is pungent, hardship, it is warm in nature.Returns spleen, Liver Channel.
With blood-breaking, the effect of inducing meastruation to relieve menalgia.For chest side of body shouting pain, amenorrhoea , wei lumps in the abdomen, rheumatism shoulder arm pain, tumbling and swelling.This hair
The research of the bright principle active component curcumin to turmeric finds that it has substantially antitumor and enhancing tumour cell to nasopharyngeal carcinoma
To the responsive type double effectses of ray.
The tuber of dwarf lilyturf：The rhizome of Liliaceae (Liliaceae) Ophiopogon plant tuber of dwarf lilyturf.Sweet, slight bitter is slightly cold.The thoughts of returning home, lung, stomach
Through.Nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire.For dryness of the lung dry cough.Tuberculosis cough, injury thirst, vexed insomnia, Heat Diabetes, intestinal dryness is just
It is secret；Pharyngeal diphtheria.
The fruit of Chinese magnoliavine：Magnoliaceae schisandra Schisandra chinensis (Turcz.) Baill. or schisandra chinensis
The dry mature fruit of Schisandra sphenanthera Rehd.et Wils..It is sour, sweet, temperature.Return lung, the heart, kidney channel.Receive
Hold back astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming.Breathed heavily for void of coughing long, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, Tianjin
Wound is thirsty, feeble pulse of losing heart, Heat Diabetes, palpitation and insomnia.
Theory of traditional Chinese medical science thinks：Easily there is dry in patient after nasopharyngeal carcinoma radiotherapy, and salivary secretion is reduced, neck fibrosis, neck
Muscular atrophy, neck attenuates, and skin of neck is belittled, difficulty in opening mouth.Hinder Tianjin gas consumption from traditional Chinese medical science angle analysis, after radiotherapy, cloudy part is big
Void, the weary source of metaplasia, therefore see dry, salivary secretion is rare, while the deficiency of vital energy then heat, radiotherapy ray is deeply worried, and fire of deficiency type excess fire is deposited simultaneously
.Rustic deficiency, soil irrigates the hypofunction on four sides, and meat gas loses supports, therefore sees neck fibrosis, and musculi colli skin withers useless.《Element
Ask that vitality of human communicating and corresponding to the universe is discussed》Point out：" yang-energy person, smart then repose, soft then nourishing the muscle and tendon ", the difficulty in opening mouth occurred after nasopharyngeal carcinoma radiotherapy is not only
Withered to local muscle useless related, at the same also with YANG QI deficiency, it is impossible to moisten foster passages through which vital energy circulates muscles and bones correlation.To sum up analyze, nasopharyngeal carcinoma radiotherapy
The interpretation of the cause, onset and process of an illness of patient empty greatly, the rustic deficiency that concentrates on cloudy part afterwards, burning hot pathogenic dryness is floating more in outer, and fire of deficiency type excess fire tangles.Our compatibility adds
Turmeric simply, for strengthening therapeutic effect during radiotherapy, simultaneously because the invigorating the lung and benefiting vital QI of Shengmai San, the work(of nourishing Yin and promoting production of body fluid.
Both the curative effect of radiotherapy can have been strengthened, side effect and adverse reaction that radiotherapy brings can have been mitigated again.
Embodiment 1 (3:3:3:2)
The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, parts by weight of schisandra chinensis medicinal material are 3:3:3:2.Ginseng, turmeric, the tuber of dwarf lilyturf, the five tastes
Son is ground into meal, and with water boiling and extraction 3 times, the amount for adding water every time is 5 times of amounts of medicinal material, boils extraction 1 hour.Merging is carried
It is 1.10/80 DEG C~1.30/80 DEG C to take liquid filtering and be concentrated by evaporation to relative density, obtains medicinal material water and extracts medicinal extract.
Embodiment 2 (3:3:3:1)
The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, parts by weight of schisandra chinensis medicinal material are 15:15:15:5.Ginseng, turmeric, the tuber of dwarf lilyturf, five
Taste is ground into meal, and with water boiling and extraction 3 times, the amount for adding water every time is 10 times of amounts of medicinal material, boils extraction 2 hours.Close
And it is 1.10/80 DEG C~1.30/80 DEG C that extract solution filtering is concentrated by evaporation to relative density, obtains medicinal material water and extract medicinal extract.
Embodiment 3 (3:3:3:1)
The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, parts by weight of schisandra chinensis medicinal material are 30:30:30:10.Ginseng, turmeric, the tuber of dwarf lilyturf,
The fruit of Chinese magnoliavine is ground into meal, and with water boiling and extraction 3 times, the amount for adding water every time is 15 times of amounts of medicinal material, boils extraction 3 hours.
Merge extract solution filtering to be concentrated by evaporation to relative density is 1.10/80 DEG C~1.30/80 DEG C, obtains medicinal material water and extracts medicinal extract.
Embodiment 4 (3:3:3:2)
The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, parts by weight of schisandra chinensis medicinal material are 60:60:60:40.Ginseng, turmeric, the tuber of dwarf lilyturf,
The fruit of Chinese magnoliavine is ground into meal, and with water boiling and extraction 3 times, the amount for adding water for the 1st time is 15 times of amounts of medicinal material, boils extraction 3 hours,
The amount for adding water for 2nd, 3 times is 10 times of amounts of medicinal material, boils extraction 2h.Merge extract solution filtering evaporation and concentration is to relative density
1.10/80 DEG C~1.30/80 DEG C, obtain medicinal material water and extract medicinal extract.
Embodiment 5 (3:3:3:2)
The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, parts by weight of schisandra chinensis medicinal material are 90:90:90:60.Ginseng, turmeric, the tuber of dwarf lilyturf,
The fruit of Chinese magnoliavine is ground into meal.Turmeric is extracted 3 times with 75% alcohol reflux, and each alcohol adding amount is 15 times of amounts of medicinal material, is carried every time
Take 3 hours.Ginseng, the tuber of dwarf lilyturf, fruit of Chinese magnoliavine water boiling and extraction 3 times, the amount for adding water every time is 15 times of amounts of medicinal material, boils extraction 3
Hour.Merge extract solution filtering to be concentrated by evaporation to relative density is 1.10/80 DEG C~1.30/80 DEG C, obtains medicinal material water and extracts medicinal extract.
Embodiment 6 (3:3:3:2)
The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, parts by weight of schisandra chinensis medicinal material are 120:120:120:80.Ginseng, turmeric, wheat
Winter, the fruit of Chinese magnoliavine is ground into meal.Turmeric is extracted 1 time with 95% alcohol reflux, and alcohol adding amount is 15 times of amounts of medicinal material, extracts 3 small
When.Extracted 2 times with 75% alcohol reflux again, each alcohol adding amount is 10 times of amounts of medicinal material, is extracted 2 hours.Ginseng, the tuber of dwarf lilyturf, the five tastes
Son uses water boiling and extraction 3 times, and the amount for adding water every time is 15 times of amounts of medicinal material, boils extraction 3 hours.Merge extract solution filtering evaporation
Relative density is concentrated to for 1.10/80 DEG C~1.30/80 DEG C, medicinal material water is obtained and is extracted medicinal extract.
Embodiment 7 (12:12:12:2)
The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, parts by weight of schisandra chinensis medicinal material are 12:12:12:2.The same embodiment of preparation method
1。
Embodiment 8 (10:10:10:10)
The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, parts by weight of schisandra chinensis medicinal material are 10:10:10:10.The same embodiment of preparation method
1。
Contrast experiment
By Shengmai San, (the ratio between ginseng, the tuber of dwarf lilyturf, parts by weight of schisandra chinensis medicinal material are 3:3:2) (implement with raw arteries and veins pulvis curcumae
Example 1 is formulated：The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, parts by weight of schisandra chinensis medicinal material are 3:3:3:2) by the preparation method system of embodiment 1
Into dry extract.
Take nasopharyngeal carcinoma CNE-2 and people immortalizes nasopharyngeal cells NP69 exponential phase cells, plant 96 orifice plates.Cell concentration
It is 5.0 × 104Individual/ml, per the μ l of hole 100, (cell number is 5.0 × 103It is individual), every group of cell sets 6 parallel control holes.Wherein CNE-
2 cells are put into after incubator culture 24h with changing liquid after linear accelerator 6MV x-ray bombardments 2Gy.Two kinds of cells are respectively by concentration ladder
Degree (12,8,4,2,1,0mg/ml) to the Shengmai San that configure with give birth to arteries and veins pulvis curcumae solution.Add 5g/L MTT solution after administration 24h
11 μ l, put back to incubator and continue to cultivate.After 4h, every hole supernatant liquid is carefully sucked, add 100 μ l and analyze pure DMSO solution, shaken
Shake 10min.M550 ELIASAs measure the absorbance per hole under 490nm wavelength.
As a result：Shengmai San and raw arteries and veins pulvis curcumae can increase the radiosensitivity of nasopharyngeal carcinoma cell CNE-2, but raw arteries and veins turmeric
Dissipate and become apparent from, as shown in Figure 1.Shengmai San and raw arteries and veins pulvis curcumae can promote people to immortalize the life of nasopharyngeal cells NP69 cells simultaneously
Grow, but raw arteries and veins pulvis curcumae becomes apparent from, as shown in Figure 2.
Claims (8)
1. the raw arteries and veins pulvis curcumae Chinese medicine composition of a kind of adjuvant therapy radiotherapy, it is characterised in that：Formula is by following components group
Into：The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, the parts by weight of the fruit of Chinese magnoliavine are：3-12:3-12:3-12:2-12.
2. the raw arteries and veins pulvis curcumae Chinese medicine composition of adjuvant therapy radiotherapy according to claim 1, it is characterised in that：Match somebody with somebody
Side is composed of the following components：The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, the parts by weight of the fruit of Chinese magnoliavine are：3-9:3-9:3-9:2-9.
3. the raw arteries and veins pulvis curcumae Chinese medicine composition of adjuvant therapy radiotherapy according to claim 1, it is characterised in that：Match somebody with somebody
Side is composed of the following components：The ratio between ginseng, turmeric, the tuber of dwarf lilyturf, the parts by weight of the fruit of Chinese magnoliavine are：3-6:3-6:3-6:2-6.
4. raw arteries and veins pulvis curcumae Chinese medicine composition is applied to prepare the medicine of adjuvant therapy radiotherapy described in claim 1-3.
5. the medicine that arteries and veins pulvis curcumae Chinese medicine composition is applied to prepare adjuvant therapy radiotherapy is given birth to according to claim 4,
It is characterized in that：Described tumour is nasopharyngeal carcinoma.
6. raw arteries and veins pulvis curcumae Chinese medicine composition is applied to prepare the medicine of adjuvant therapy radiotherapy according to claim 4 or 5
Thing, it is characterised in that：The preparation method of the medicine is comprised the following steps：(1) ginseng, turmeric, the tuber of dwarf lilyturf, the five tastes are weighed by formula
Son, crushes；(2) turmeric is extracted 2-3 times with 40%-95% alcohol refluxs, ginseng, the tuber of dwarf lilyturf, fruit of Chinese magnoliavine water boiling and extraction 2-3
It is secondary, add alcohol or water to be 5-15 times, each refluxing extraction 1-3 hours of medicinal material amount every time；Or, ginseng, the tuber of dwarf lilyturf, the fruit of Chinese magnoliavine, ginger
Huang uses water boiling and extraction 2-3 times, and the amount for adding water every time is 5-15 times of medicinal material and measures, and boils extraction 1-3 hours；(3) merge and extract
It is 1.10/80 DEG C -1.30/80 DEG C that liquid filtering is concentrated by evaporation to relative density, obtains medicinal material extract medicinal extract；(4) corresponding medicine is added
Mixed with auxiliary material, preparation is made by the technique of corresponding formulation.
7. raw arteries and veins pulvis curcumae Chinese medicine composition is applied to prepare the medicine of adjuvant therapy radiotherapy according to claim 4 or 5
Thing, it is characterised in that：The formulation of described medicine be decoction, pill, powder, paste, sublimed preparation, vina, syrup, extract,
Lozenge, distillate medicinal water, jelly, medicinal tea, nail agent, stylus, suppository, herbal leaven, paste, cake agent, wash liniment, finish, line agent, medicated roll, press agent,
Process agent, fumicants, medicine perfume (or spice) etc., tablet, electuary, bagged instant preparation, oral solutions, capsule, pill, mixture, tincture, aerosol, filling
Intestines agent, film, eye-drops preparations, nasal formulations, sponginum or injection.
8. raw arteries and veins pulvis curcumae Chinese medicine composition is applied to prepare the medicine of adjuvant therapy radiotherapy according to claim 4 or 5
Thing, it is characterised in that：The formulation of described medicine is peroral dosage form.
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| CN201710008060.1A CN106729422B (en) | 2017-01-05 | 2017-01-05 | Pulse-activating turmeric powder traditional Chinese medicine composition for assisting tumor radiotherapy and application thereof |
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| CN201710008060.1A CN106729422B (en) | 2017-01-05 | 2017-01-05 | Pulse-activating turmeric powder traditional Chinese medicine composition for assisting tumor radiotherapy and application thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109170892A (en) * | 2018-09-29 | 2019-01-11 | 首益特殊医学用途配方食品科技研究（北京）有限公司 | Diet therapy nutritional element solid beverage and preparation method thereof for tumor recovering |
-
2017
- 2017-01-05 CN CN201710008060.1A patent/CN106729422B/en not_active Expired - Fee Related
Non-Patent Citations (3)
| Title |
|---|
| 王文等: ""生脉注射液对鼻咽癌放疗减毒增效作用的临床观察"", 《浙江中医学院学报》 * |
| 苗苗等: ""生脉注射液对不同化疗药物的增敏作用"", 《中草药》 * |
| 范昊宁: ""姜黄素对人鼻咽癌细胞放射增敏作用及其机制研究"", 《中国博士学位论文全文数据库 医药卫生科技辑》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109170892A (en) * | 2018-09-29 | 2019-01-11 | 首益特殊医学用途配方食品科技研究（北京）有限公司 | Diet therapy nutritional element solid beverage and preparation method thereof for tumor recovering |
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| Publication number | Publication date |
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| CN106729422B (en) | 2020-09-04 |
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