CN106729083A - It is a kind of to treat medicine of periodontitis and preparation method thereof - Google Patents

It is a kind of to treat medicine of periodontitis and preparation method thereof Download PDF

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CN106729083A
CN106729083A CN201611240130.8A CN201611240130A CN106729083A CN 106729083 A CN106729083 A CN 106729083A CN 201611240130 A CN201611240130 A CN 201611240130A CN 106729083 A CN106729083 A CN 106729083A
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张秀兰
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    • A61K36/88Liliopsida (monocotyledons)
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Abstract

Medicine of periodontitis and preparation method thereof is treated the invention discloses a kind of, it is mainly and is prepared from according to a certain weight ratio by purslane, the rhizome of davallia, the root of bidentate achyranthes, caulis lonicerae, the capsule of weeping forsythia, rhizoma imperatae, moutan bark, paniculate swallowwort, chrysanthemum indicum, radix rehmanniae recen, asarum, golden cypress, the root of Chinese clematis, garden burnet, madder, folium isatidis, blackberry lily, the wind-weed, honeysuckle, the root of Dahurain angelica, gypsum, the root bark of Chinese wolf-berry, sophora flower, medicine of the present invention has dispelling wind and heat from the body, purging intense heat and detonicating, swelling and pain relieving, facilitaing lung opens the function of sound, for treating periodontitis instant effect, good effect, do not recur.

Description

It is a kind of to treat medicine of periodontitis and preparation method thereof
Technical field
Medicine of periodontitis and preparation method thereof is treated the present invention relates to a kind of, belongs to the field of Chinese medicines.
Technical background
Periodontitis refers to that a kind of chronic destructive disease in gum, parodontium, alveolar bone, cementum etc. occurs, and can be made Tooth supporting tissue is gradually destroyed, and root of the tooth surrounding tissue chronic inflammation suppurates, and alveolar osteanabrosis, tooth mobility can not be chewed Food, can finally make entire mouth come off.The traditional Chinese medical science then thinks to belong to pingival atrophy, bleeding from the gum category, more by steaming in stomach fire, the deficiency of the kidney yin, Caused by being invaded outside burning hot evil poison.Because western medicine side effect is big, therefore people exist to the Chinese medicine of effectively treatment periodontitis Great demand, up to now, it has not been found that on relevant report of the invention.
The content of the invention
The present inventor have found effectively treatment periodontal finally according to the checking repeatedly of research and the clinical test of theory of traditional Chinese medical science Scorching medicine, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effective treatment periodontitis.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention be selection purslane, the rhizome of davallia, the root of bidentate achyranthes, caulis lonicerae, the capsule of weeping forsythia, rhizoma imperatae, moutan bark, paniculate swallowwort, Chrysanthemum indicum, radix rehmanniae recen, asarum, golden cypress, the root of Chinese clematis, garden burnet, madder, folium isatidis, blackberry lily, the wind-weed, honeysuckle, the root of Dahurain angelica, gypsum, Bone skin, sophora flower, subprostrate sophora, cattail pollen, selfheal, Radix Glycyrrhizae, rattletop, dandelion, radix boehmeriae medicine are combined preparation, by these Drug regimen causes that each efficacy of drugs produces synergy such that it is able to effectively treat periodontitis.Wherein from purslane be because It is the acid of its nature and flavor, trembles with fear, enter large intestine, liver, the spleen channel, there is clearing heat and detoxicating, dissipate the function of blood detumescence, controls hot dysentery purulence blood, heat gonorrhea, blood strangury, Under band, Carbuncle swells dislikes sore, erysipelas, scrofula.From the rhizome of davallia because its is bitter in taste, temperature enters liver and kidney channel, there is kidney tonifying, invigorates blood circulation, only The function of blood, controls kidney deficiency chronic diarrhea and pain in the back, arthralgia pain due to rheumatism, dentalgia, tinnitus, the bruise sudden strain of a muscle, bone fracture, appendicitis, alopecia areata, corn. From the root of bidentate achyranthes because its nature and flavor sweetness and bitterness is sour, put down, enter liver and kidney channel, life scattered blood stasis, the function of subduing inflammation controls gonorrhoea, hematuria, Amenorrhea , Disorder lumps in the abdomen, difficult labour, placenta retension, postpartum blood stasis stomachache, larynx numbness, carbuncle swells, traumatic injury, ripe use filling liver kidney, strengthening the bones and muscles is controlled Control waist and knee ostalgia, spasm of limbs, Impotence numbness.From caulis lonicerae because its nature and flavor is sweet, tremble with fear, enter the heart, lung channel, there is heat-clearing, detoxify, dredging collateral Function, control warm disease heating, toxic-heat and blood stasis, catarrhal jaundice, carbuncle sore tumefacting virus, arthralgia and myalgia.From the capsule of weeping forsythia because its nature and flavor Hardship, it is cool, enter the heart, liver, gallbladder channel, there is heat-clearing, to detoxify, dissipating bind, the function of detumescence controls warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula Scrofula, urine leaching closes.From rhizoma imperatae because its nature and flavor is sweet, cold, enter lung, stomach, small intestinl channel, there is cool blood, stop blooding, heat-clearing, diuresis Function, control pyreticosis polydipsia, spit blood, bleeding from five sense organs or subcutaneous tissue, lung heat breathes heavily urgency, stomach energy hiccup, gonorrhoea, difficult urination, oedema, jaundice.From male The root bark of tree peony is cool because its nature and flavor is arduous, enters the heart, liver and kidney channel, there is heat-clearing, cool blood, and blood, and the function of dispersing blood stasis controls heat invading xuefen, Hair spot , Jing Epilepsy, tells, is defeated in battle, has blood in stool, and hectic fever due to yin labor heat, Amenorrhea , Disorder lumps in the abdomen, large carbuncle flutters damage.From paniculate swallowwort because its nature and flavor is pungent, Temperature, there is analgesia, and cough-relieving, inducing diuresis for removing edema, the function of promoting blood circulation and detoxication is treated for stomachache, toothache, rheumatalgia pain, bellyache in menstrual period, Chronic Airway Inflammation, ascites, oedema, dysentery, enteritis, traumatic injury, eczema, nettle rash, venomous snake bite.From chrysanthemum indicum because its is bitter in taste It is pungent, it is cool, enter lung, Liver Channel, there is a wind and heat dispersing, the function of subdhing swelling and detoxicating controls anemopyretic cold, pneumonia, diphtheria, gastroenteritis, hypertension, Malignant boil, carbuncle, aphtha, erysipelas, eczema, epidemic blisters.From radix rehmanniae recen because its nature and flavor is sweet, tremble with fear, the thoughts of returning home, liver and kidney channel have heat-clearing cool Blood, yin-nourishing, the function of promoting the production of body fluid controls pyreticosis polydipsia, and yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, Heat Diabetes is spitted blood, bleeding from five sense organs or subcutaneous tissue, spot dermexanthesis. From asarum because its nature and flavor is pungent, temperature enters lung, kidney channel, there is wind-dispelling, and cold dispelling, water-filling is opened function surreptitiously, controls air-cooled headache, nose Deep pool, analgesic, phlegm and retained fluid coughs inverse, arthralgia pain due to rheumatism.From golden cypress because its is bitter in taste, tremble with fear, enter kidney, bladder warp, there is a heat-clearing, eliminating dampness, Purging intense heat, the function of removing toxic substances controls hot dysentery, and diarrhea is quenched one's thirst, and jaundice , crippling wilts, nocturnal emission, stranguria with turbid discharge, hemorrhoid are had blood in stool, leukorrhea with reddish discharge, hectic fever due to yin Labor heat, red eye, swell pain, aphthae, sore swollen toxin.From the root of Chinese clematis because its nature and flavor is pungent salty, temperature is poisonous, enters bladder warp, There is a wind-damp dispelling, degrading the channel, dissolving phlegm saliva, the function of dissipate the hypochondriac lump controls gout, stupid numbness, waist and knee crymodynia, tinea pedis, malaria , lumps in the chest and abdomen, Lockjaw, tonsillitis, all bone sticking swallow.From garden burnet because its nature and flavor picric acid, trembles with fear, enter liver, large intestine channel have cooling blood and hemostasis, Clearing heat and detoxicating function, controls haematemesis, bleeding from five sense organs or subcutaneous tissue, bloody flux, uterine bleeding, intestines wind, anal fistula, carbuncle swells, eczema, metal-inflicted wound, burn.It is from madder Because its is bitter in taste, tremble with fear, return liver warp has cooling blood and hemostasis, and the function of Stasis through controls haematemesis, bleeding from five sense organs or subcutaneous tissue, uterine bleeding, traumatism and bleeding, the stasis of blood Resistance Amenorrhea, joint pain, tumbling and swelling.From folium isatidis because its is bitter in taste, tremble with fear, enter liver, the heart, stomach have heat-clearing, solution Poison, cool blood, the function of hemostasis, control warm disease heat contain polydipsia, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, Acute pneumonia, erysipelas is spitted blood, bleeding from five sense organs or subcutaneous tissue, jaundice, dysentery, larynx numbness, aphtha, swollen ulcer drug.From blackberry lily because its is bitter in taste, It is cold, it is poisonous, enter lung, Liver Channel, there is fall fire, detoxify, blood is dissipated, the function of dissolving phlegm controls larynx numbness pharyngalgia, cough with dyspnea, accumulation and obstruction of sputum, scrofula Scrofula tuberculosis, malaria is female, women's Amenorrhea, carbuncle sore tumefacting virus.From the wind-weed because its is bitter in taste, tremble with fear, enter lung, stomach, kidney channel, there is enriching yin to drop Fire, the function of moisturize laxation is controlled dysphoria with smothery sensation and is quenched one's thirst, hectic fever due to yin labor heat, cough with lung heat, dry feces, difficult urination.It is from honeysuckle Because its nature and flavor is sweet, tremble with fear, enter lung, stomach, there is heat-clearing, the function of removing toxic substances controls warm disease heating, toxic-heat and blood stasis, large carbuncle, pyogenic infections, scrofula Scrofula, anal fistula.From the root of Dahurain angelica because its nature and flavor is pungent, temperature enters lung, spleen, stomach, there is wind-dispelling, and eliminating dampness, detumescence, the function of analgesic is controlled Headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin is dry itches, mange.Choosing With gypsum because its property acrid-sweet flavor, trembles with fear, enter lung, stomach, raw with there is expelling pathogenic factors from muscles for clearing heat, the function that relieving restlessness is quenched the thirst controls pyreticosis high fever Do not move back, vexed coma, delirious speech is gone mad, thirsty and dry pharynx, lung heat breathes heavily urgency, heatstroke spontaneous perspiration, stomach headache due to fire-evil, toothache, heat toxin is stopped up Sheng, sends out spot Dermexanthesis, aphthae forges deposited myogenic sore, and ulcer sores are controlled outward, bursts and does not withdraw, the burning hot wound of soup.From the root bark of Chinese wolf-berry because its Nature and flavor are sweet, tremble with fear, and enter lung, liver and kidney channel, there is heat-clearing, and the function of cool blood controls consumptive disease hectic fever night sweat, and lung heat cough and asthma is spitted blood, bleeding from five sense organs or subcutaneous tissue, blood Drench, quench one's thirst, hypertension, carbuncle swells dislike sore.Cool from sophora flower because its is bitter in taste, enter liver, large intestine channel have a heat-clearing, cool blood, only The function of blood, controls hematochezia, hemorrhoid blood, hematuria, blood strangury, uterine bleeding, bleeding from five sense organs or subcutaneous tissue, and under dysentery, wind-heat hot eyes, skin sore is used in combination In prevention of stroke.From subprostrate sophora because its is bitter in taste, tremble with fear, enter the heart, lung, the warp of large intestine three, relieve inflammation or internal heat, detoxify, detumescence, analgesic Function, control retropharyngeal abscess, sore-throat, larynx numbness, swelling and aching of gum is breathed heavily full heat and is coughed, jaundice, diarrhea, haemorrhoids, and heat is swollen, the favus of the scalp, mange, snake, Worm, dog bite.From cattail pollen because its nature and flavor is sweet arduous, cool, enter liver, the heart channel of Hang-Shaoyin have a cooling blood and hemostasis, the function of activating blood circulation and dissipating blood stasis, Raw controlling through closing is suffered from abdominal pain, and postpartum stasis are had a pain, and falls vexed, sore furuncle poison of flutterring blood, fries black antiemetic blood, bleeding from five sense organs or subcutaneous tissue, uterine bleeding, rushes down blood, hematuria, Bloody flux, under band controls outward double tongue, aphtha, Ting discharging ear, bleeding in ear, uncontrolled urination.From selfheal because its is bitter in taste It is pungent, to tremble with fear, enter liver, gallbladder channel have clearing liver, and the function of dissipating bind controls scrofula, and goiter and tumor, acute mastitis, breast cancer, mesh pearl nyctalgia, photophobia is shed tears, head It is dizzy dizzy, facial paralysis, arthralgia and myalgia, pulmonary tuberculosis, acute icteric catarrhal jaundice, metrorrhagia, under band.From Radix Glycyrrhizae because Its property sweet taste, enters spleen, stomach, lung channel, has and processs, food weakness of the spleen and the stomach with controlling with middle emergency, moistening lung, removing toxic substances, the function of coordinating the drug actions of a prescription Few, stomachache loose stool, overstrain heating, consumptive lung disease cough, palpitaition shies carbuncle, and raw with abscess of throat is controlled, peptic ulcer, ulcer sores are solved Medicine poison and food poisoning.From rattletop because its property acrid-sweet flavor slight bitter, cool, enter lung, spleen, stomach, there is rising Yang, deliver, promoting eruption, The function of removing toxic substances, gas epidemic disease labor when controlling, fever and chills of having a headache, laryngalgia, aphtha scar, macula is impermeable, the sinking of qi of middle-jiao, protracted dysentery and diarrhea, prolapse of the anus, woman Female collapses band, uterus tenesmus, carbuncle sore tumefacting virus.From dandelion because its nature and flavor bitter sweet, trembles with fear, enter liver, stomach have clearing heat and detoxicating, The function of diuresis dissipating bind, controls acute mastitis, and adenolymphitis, scrofula, malignant boil carbuncle toxin, acute conjunctivitis, cold, fever is acute flat Peach body is scorching, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections.From radix boehmeriae because its nature and flavor is sweet, tremble with fear, enter Meridian of Foot-JUE YIN, there is reducing fever and causing diuresis, antiabortive hemostasis, the function of removing toxic substances, the heating that cures cold, measles high fever, urinary tract infections, ephritis water Swollen, pregnant woman's stomachache, fetal irritability, threatened abortion, traumatic injury, fracture, sore swell and ache curative, hemorrhagic disease.
Specific embodiment
The drug dose of instant component is also that inventor summarizes what is drawn by largely groping, and the consumption of each component is under Stating all has preferable curative effect in weight range:
15-25 grams of purslane, 8-12 grams of the rhizome of davallia, 12-18 grams of the root of bidentate achyranthes, 8-12 grams of caulis lonicerae, 8-12 grams of the capsule of weeping forsythia, rhizoma imperatae 10- 15 grams, 12-18 grams of moutan bark, 8-12 grams of paniculate swallowwort, 10-15 grams of chrysanthemum indicum, 8-12 grams of radix rehmanniae recen, 10-15 grams of asarum, golden cypress 8- 12 grams, 10-15 grams of the root of Chinese clematis, 8-12 grams of garden burnet, 8-12 grams of madder, 6-10 grams of folium isatidis, 12-18 grams of blackberry lily, wind-weed 12-18 Gram, 10-15 grams of honeysuckle, 8-12 grams of the root of Dahurain angelica, 8-12 grams of gypsum, 15-25 grams of the root bark of Chinese wolf-berry, 8-12 grams of sophora flower, subprostrate sophora 10-15 Gram, 15-25 grams of cattail pollen, 15-25 grams of selfheal, 10-15 grams of Radix Glycyrrhizae, 8-12 grams of rattletop, 6-10 grams of dandelion, radix boehmeriae 12-18 Gram.
Preferable amount is
20 grams of purslane, 10 grams of the rhizome of davallia, 15 grams of the root of bidentate achyranthes, 10 grams of caulis lonicerae, 10 grams of the capsule of weeping forsythia, 12 grams of rhizoma imperatae, 15 grams of moutan bark, 10 grams of paniculate swallowwort, 12 grams of chrysanthemum indicum, 10 grams of radix rehmanniae recen, 12 grams of asarum, 10 grams of golden cypress, 12 grams of the root of Chinese clematis, 10 grams of garden burnet, madder 10 Gram, 8 grams of folium isatidis, 15 grams of blackberry lily, 15 grams of the wind-weed, 12 grams of honeysuckle, 10 grams of the root of Dahurain angelica, 10 grams of gypsum, 20 grams of the root bark of Chinese wolf-berry, sophora flower 10 Gram, 12 grams of subprostrate sophora, 20 grams of cattail pollen, 20 grams of selfheal, 12 grams of Radix Glycyrrhizae, 10 grams of rattletop, 8 grams of dandelion, 15 grams of radix boehmeriae.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, purslane:Net impurity is picked, undesirable root is removed, is slightly moistened with water, segment is dried;
2nd, the rhizome of davallia:Sediment contamination is removed, is cleaned, slightly soaked, run through, cut into slices, dried;
3rd, the root of bidentate achyranthes:Impurity is picked, is cleaned, softened, go reed, segment is dried;
4th, caulis lonicerae:Impurity is picked, is soaked in water, run through, cut into slices, dried;
5th, the capsule of weeping forsythia:Net impurity is picked, stranding is opened, except discarding stalk;
6th, rhizoma imperatae:Net impurity is picked, is cleaned, micro- profit, segment is dried, net chip of winnowing with a dustpan;
7th, moutan bark:Impurity is picked, core is removed, cleaned, run through, cut into slices, dried;
8th, paniculate swallowwort:Net impurity is picked, is cleaned, run through, be cut into 1.5 centimetres of sections, dried;
9th, chrysanthemum indicum:Impurity is removed, undesirable root is removed, segment is cleaned, dried;
10th, radix rehmanniae recen:Crude drug is taken, impurity is removed, cleaned, slightly moistened, cut sheet, dried, weed out chip;
11st, asarum:Cleared impurity, is sprayed with water and moistened, and timely segment is dried;
12nd, golden cypress:Impurity is picked, is washed, pulled out, run through, cut into slices or chopping, dried;
13rd, the root of Chinese clematis:Net impurity is picked, residual stem is removed, is soaked in water, pulled out and run through, segment is dried;
14th, garden burnet:Impurity is picked, is washed, slightly soaked, run through, be cut into sheet, dried;
15th, madder:Impurity is removed, is cleaned, run through, cut sheet or section, dried, weed out chip;
16th, folium isatidis:Impurity and dead leaf are picked, is cleaned, slightly moistened, segment is dried;
17th, blackberry lily:Impurity is picked, water is cleaned, slightly soaked, pull out, runs through, and is cut into slices, and is dried, weed out and must, consider to be worth doing;
18th, the wind-weed:Net impurity is picked, is hit with water and washed, pulled out, softened, section is dried;
19th, honeysuckle:Silt is weeded out, net impurity is picked;
20th, the root of Dahurain angelica:Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after vexed profit, cut Piece is dried;
21st, gypsum:Miscellaneous stone is removed, soil is cleaned, fritter is broken into;
22nd, the root bark of Chinese wolf-berry:Impurity and core are picked, is slightly washed, segment is dried;
23rd, sophora flower:Crude drug is taken, stalk, leaf and impurity is removed, grey bits are weeded out;
24th, subprostrate sophora:Net impurity is picked, thickness stepping is soaked in water, pulls out, cut into slices after running through, dried;
25th, cattail pollen:Broken caking is rubbed, is sieved, remove impurity;
26th, selfheal:Crude drug is taken, except discarding stalk, blade and impurity, grey bits is weeded out;
27th, Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, airing;
28th, rattletop:Impurity is picked, slightly foam washing is net, pulls out, runs through, and cuts into slices, and dries;
29th, dandelion:Impurity is picked, soil is cleaned, segment is dried;
30th, radix boehmeriae:Crude drug is taken, impurity is removed, cleaned, run through, cut sheet, dried.
2nd, prepare
1st, by the purslane of the weight, the rhizome of davallia, the root of bidentate achyranthes, caulis lonicerae, the capsule of weeping forsythia, rhizoma imperatae, moutan bark, paniculate swallowwort, chrysanthemum indicum, Radix rehmanniae recen, asarum, golden cypress, the root of Chinese clematis, garden burnet, madder, folium isatidis, blackberry lily, the wind-weed, honeysuckle, the root of Dahurain angelica, gypsum, the root bark of Chinese wolf-berry, Chinese scholartree Flower, subprostrate sophora, cattail pollen, selfheal, Radix Glycyrrhizae, rattletop, dandelion, radix boehmeriae are put into decocting container, are added water for the first time 8 times and are measured, After immersion 100 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, filter to obtain first time decoction liquor, first time is decocted Liquid is poured into container;
2nd, the dregs of a decoction of filtering are added water 6 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor;
3rd, will decoction liquor mixing and stirring twice, be divided into 4 doses and take.
Great burdock achene has a dispelling wind and heat from the body in prescription, facilitaing lung promoting eruption, and the function of subdhing swelling and detoxicating is monarch drug in a prescription;Subprostrate sophora relieves inflammation or internal heat, removing toxic substances, Detumescence, analgesic;The coptis has a purging intense heat, eliminating dampness, removing toxic substances, the function of desinsection, and the two is ministerial drug, and three taste medicines play dispelling wind jointly, purging intense heat, Removing toxic substances, detumescence, the effect of analgesic, treatment periodontitis effect comprehensively, and with dispelling wind, can effect a permanent cure based on purging intense heat, and the sterculia seed has heat-clearing, Moistening lung, relieving sore-throat, the function of removing toxic substances is adjutant, Radix Glycyrrhizae have with middle emergency, moistening lung, removing toxic substances, the function of coordinating the drug actions of a prescription is and remaining to make medicine Under all medicines be to take stopgap measures.
Medicine of the present invention has dispelling wind and heat from the body, and purging intense heat and detonicating, swelling and pain relieving, facilitaing lung opens the function of sound, for treating periodontal Inflammation, short treating period, instant effect, non-relapse after healing.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include this hair The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention:
Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, and every group 15, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, takes medicine continuously 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic and side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept periodontitis out-patient totally 30 for medical treatment.
2nd, diagnostic criteria
Early symptom is not obvious, and patient often only has the performance of Secondary cases bleeding gums or halitosis, similar to symptoms of gingivitis.During inspection It can be seen that gum edge, the swelling of gum nipple and attached gingiva, matter are soft, in peony or kermesinus, easy bleeding is examined in spy.With entering for inflammation One step spreads, and following symptoms occurs:
(1)Periodontal bag formation:Because the extension of inflammation, parodontium are destroyed, alveolar bone is gradually absorbed, and gum is separated with root of the tooth, Gingival sulcus is set to deepen and form oral pocket.Depth of pocket can be surveyed with probe;
(2)Periodontal pyorrhea:Oral pocket wall has ulcer and inflammatory granulation tissue to be formed, and has purulent secretion to retain in bag, therefore gently Press gum, it is seen that pyorrhea simultaneously often has halitosis;
(3)Tooth mobility:Because periodontium is destroyed, when particularly absorption of alveolar bone is aggravated, support that tooth strength is not enough, go out The phenomenons such as existing tooth mobility, displacement.Now patient often feels the powerless, dull pain of occlusion, and bleeding gums and halitosis are aggravated.
When Abwehrkraft des Koepers reduction, oral pocket sepage inadequate drainage, periodontal abscess can be formed, it is late to be that periodontitis is developed into Phase, a common concomitant symptom for deep oral pocket occur.Now gum is in oval projection, rubescent swelling, surface-brightening;Tooth Loose compact degree increases, and kowtows pain;Patient acutely jumps pain with local.Meanwhile, patient can have body temperature to raise, general malaise, under jaw The symptoms such as enlargement of lymph nodes, tenderness.
3rd, treatment method
From above-mentioned medicament, taken to patient, each take 1 dose, early daily, evening respectively takes 1 time, be within 5 days a course for the treatment of, continuous clothes With 5 courses for the treatment of.
4th, efficacy assessment standard
It is effective:Periodontitis symptom disappears, and constitution recovers normal, recovery from illness;
Take a turn for the better:Patient's bleeding gums, halitosis phenomenon mitigate, and periodontitis symptom is clearly better, and constitution is progressively recovered;
It is invalid:Improvement standard person is not reached.
5th, treatment results(See the table below)
In above-mentioned treatment, with drug therapy patients with periodontitis of the present invention 30, as a result effective 27, obvious effective rate is 90%, is taken a turn for the better 2, improvement rate is 6.67%, and invalid 1, total effective rate is 96.67%.

Claims (3)

1. a kind of medicine for treating periodontitis, it is characterised in that:It is made up of the bulk drug in following weight range:
15-25 grams of purslane, 8-12 grams of the rhizome of davallia, 12-18 grams of the root of bidentate achyranthes, 8-12 grams of caulis lonicerae, 8-12 grams of the capsule of weeping forsythia, rhizoma imperatae 10- 15 grams, 12-18 grams of moutan bark, 8-12 grams of paniculate swallowwort, 10-15 grams of chrysanthemum indicum, 8-12 grams of radix rehmanniae recen, 10-15 grams of asarum, golden cypress 8- 12 grams, 10-15 grams of the root of Chinese clematis, 8-12 grams of garden burnet, 8-12 grams of madder, 6-10 grams of folium isatidis, 12-18 grams of blackberry lily, wind-weed 12-18 Gram, 10-15 grams of honeysuckle, 8-12 grams of the root of Dahurain angelica, 8-12 grams of gypsum, 15-25 grams of the root bark of Chinese wolf-berry, 8-12 grams of sophora flower, subprostrate sophora 10-15 Gram, 15-25 grams of cattail pollen, 15-25 grams of selfheal, 10-15 grams of Radix Glycyrrhizae, 8-12 grams of rattletop, 6-10 grams of dandelion, radix boehmeriae 12-18 Gram.
2. medicine according to claim 1, wherein the consumption of each bulk drug is:
20 grams of purslane, 10 grams of the rhizome of davallia, 15 grams of the root of bidentate achyranthes, 10 grams of caulis lonicerae, 10 grams of the capsule of weeping forsythia, 12 grams of rhizoma imperatae, 15 grams of moutan bark, 10 grams of paniculate swallowwort, 12 grams of chrysanthemum indicum, 10 grams of radix rehmanniae recen, 12 grams of asarum, 10 grams of golden cypress, 12 grams of the root of Chinese clematis, 10 grams of garden burnet, madder 10 Gram, 8 grams of folium isatidis, 15 grams of blackberry lily, 15 grams of the wind-weed, 12 grams of honeysuckle, 10 grams of the root of Dahurain angelica, 10 grams of gypsum, 20 grams of the root bark of Chinese wolf-berry, sophora flower 10 Gram, 12 grams of subprostrate sophora, 20 grams of cattail pollen, 20 grams of selfheal, 12 grams of Radix Glycyrrhizae, 10 grams of rattletop, 8 grams of dandelion, 15 grams of radix boehmeriae.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps:
(One)Get the raw materials ready
(1)Purslane:Net impurity is picked, undesirable root is removed, is slightly moistened with water, segment is dried;
(2)The rhizome of davallia:Sediment contamination is removed, is cleaned, slightly soaked, run through, cut into slices, dried;
(3)The root of bidentate achyranthes:Impurity is picked, is cleaned, softened, go reed, segment is dried;
(4)Caulis lonicerae:Impurity is picked, is soaked in water, run through, cut into slices, dried;
(5)The capsule of weeping forsythia:Net impurity is picked, stranding is opened, except discarding stalk;
(6)Rhizoma imperatae:Net impurity is picked, is cleaned, micro- profit, segment is dried, net chip of winnowing with a dustpan;
(7)Moutan bark:Impurity is picked, core is removed, cleaned, run through, cut into slices, dried;
(8)Paniculate swallowwort:Net impurity is picked, is cleaned, run through, be cut into 1.5 centimetres of sections, dried;
(9)Chrysanthemum indicum:Impurity is removed, undesirable root is removed, segment is cleaned, dried;
(10)Radix rehmanniae recen:Crude drug is taken, impurity is removed, cleaned, slightly moistened, cut sheet, dried, weed out chip;
(11)Asarum:Cleared impurity, is sprayed with water and moistened, and timely segment is dried;
(12)Golden cypress:Impurity is picked, is washed, pulled out, run through, cut into slices or chopping, dried;
(13)The root of Chinese clematis:Net impurity is picked, residual stem is removed, is soaked in water, pulled out and run through, segment is dried;
Garden burnet:Impurity is picked, is washed, slightly soaked, run through, be cut into sheet, dried;
(15)Madder:Impurity is removed, is cleaned, run through, cut sheet or section, dried, weed out chip;
(16)Folium isatidis:Impurity and dead leaf are picked, is cleaned, slightly moistened, segment is dried;
(17)Blackberry lily:Impurity is picked, water is cleaned, slightly soaked, pull out, runs through, and is cut into slices, and is dried, weed out and must, consider to be worth doing;
(18)The wind-weed:Net impurity is picked, is hit with water and washed, pulled out, softened, section is dried;
(19)Honeysuckle:Silt is weeded out, net impurity is picked;
(20)The root of Dahurain angelica:Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after vexed profit, cut Piece is dried;
(21)Gypsum:Miscellaneous stone is removed, soil is cleaned, fritter is broken into;
(22)The root bark of Chinese wolf-berry:Impurity and core are picked, is slightly washed, segment is dried;
(23)Sophora flower:Crude drug is taken, stalk, leaf and impurity is removed, grey bits are weeded out;
(24)Subprostrate sophora:Net impurity is picked, thickness stepping is soaked in water, pulls out, cut into slices after running through, dried;
(25)Cattail pollen:Broken caking is rubbed, is sieved, remove impurity;
(26)Selfheal:Crude drug is taken, except discarding stalk, blade and impurity, grey bits is weeded out;
(27)Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, airing;
(28)Rattletop:Impurity is picked, slightly foam washing is net, pulls out, runs through, and cuts into slices, and dries;
(29)Dandelion:Impurity is picked, soil is cleaned, segment is dried;
(30)Radix boehmeriae:Crude drug is taken, impurity is removed, cleaned, run through, cut sheet, dried;
(Two)Prepare
(1)By the purslane of the weight, the rhizome of davallia, the root of bidentate achyranthes, caulis lonicerae, the capsule of weeping forsythia, rhizoma imperatae, moutan bark, paniculate swallowwort, mother chrysanthemum Flower, radix rehmanniae recen, asarum, golden cypress, the root of Chinese clematis, garden burnet, madder, folium isatidis, blackberry lily, the wind-weed, honeysuckle, the root of Dahurain angelica, gypsum, bone Skin, sophora flower, subprostrate sophora, cattail pollen, selfheal, Radix Glycyrrhizae, rattletop, dandelion, radix boehmeriae are put into decocting container, are added water 8 times and are measured, leaching Bubble is fried by intense fire to boil and risen after 100 minutes, then with being cooked by slow fire 20 minutes, filters to obtain first time decoction liquor, by first time decoction liquor Pour into container;
(2)The dregs of a decoction of filtering are added water 6 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor;
(3)Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 4 doses and is taken.
CN201611240130.8A 2016-12-29 2016-12-29 It is a kind of to treat medicine of periodontitis and preparation method thereof Withdrawn CN106729083A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2754828C1 (en) * 2021-01-11 2021-09-08 федеральное государственное бюджетное образовательное учреждение высшего образования "Башкирский государственный медицинский университет" Министерства здравоохранения Российской Федерации Dental gel for treatment of inflammatory diseases of periodontal and mucosa of oral cavity, arising on background of psychoemotional stress

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Publication number Priority date Publication date Assignee Title
CN1857587A (en) * 2006-03-21 2006-11-08 北京阜康仁生物制药科技有限公司 Compound Chinese medicine preparation for clearing stomach heat, nourishing Yin and cooling blood and its preparing process
CN103919915A (en) * 2014-04-28 2014-07-16 四川金堂海纳生物医药技术研究所 Oral medicine for treating apicitis and preparation method thereof
CN104740182A (en) * 2015-04-12 2015-07-01 丰蓉 Traditional Chinese medicine composition for treating periodontitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1857587A (en) * 2006-03-21 2006-11-08 北京阜康仁生物制药科技有限公司 Compound Chinese medicine preparation for clearing stomach heat, nourishing Yin and cooling blood and its preparing process
CN103919915A (en) * 2014-04-28 2014-07-16 四川金堂海纳生物医药技术研究所 Oral medicine for treating apicitis and preparation method thereof
CN104740182A (en) * 2015-04-12 2015-07-01 丰蓉 Traditional Chinese medicine composition for treating periodontitis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2754828C1 (en) * 2021-01-11 2021-09-08 федеральное государственное бюджетное образовательное учреждение высшего образования "Башкирский государственный медицинский университет" Министерства здравоохранения Российской Федерации Dental gel for treatment of inflammatory diseases of periodontal and mucosa of oral cavity, arising on background of psychoemotional stress

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Application publication date: 20170531