CN106728619A - A kind of composition for preventing and treating fish streptococcosis - Google Patents

A kind of composition for preventing and treating fish streptococcosis Download PDF

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Publication number
CN106728619A
CN106728619A CN201710126167.6A CN201710126167A CN106728619A CN 106728619 A CN106728619 A CN 106728619A CN 201710126167 A CN201710126167 A CN 201710126167A CN 106728619 A CN106728619 A CN 106728619A
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parts
streptococcosis
composition
fish
preventing
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CN201710126167.6A
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Chinese (zh)
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苏金武
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Changsha Ruiduokang Biotechnology Co Ltd
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Changsha Ruiduokang Biotechnology Co Ltd
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Priority to CN201710126167.6A priority Critical patent/CN106728619A/en
Publication of CN106728619A publication Critical patent/CN106728619A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Fodder In General (AREA)

Abstract

The present invention relates to a kind of composition for preventing and treating fish streptococcosis, it is characterised in that be made up of the raw material of following weight portion:6~10 parts of folium artemisiae argyi, 2~5 parts of betel nut, 6~10 parts of the coptis, 3~6 parts of Radix Glycyrrhizae, 3~6 parts of the root of large-flowered skullcap, 8~12 parts of radix bupleuri, 5~8 parts of camphorwood, 10~15 parts of Honeysuckle flower, 5~8 parts of great burdock achene.The present invention has preferable resistant effect, and energy effectively preventing fish streptococcosis is reduced because fish streptococcosis is dead, had no toxic side effect and medicament residue, and production cost is relatively low, easy to use.

Description

A kind of composition for preventing and treating fish streptococcosis
Technical field
The present invention is related to the disease treatment of the fish in aquaculture, and in particular to a kind of preventing and treating fish streptococcosis Composition.
Background technology
Fish streptococcus is one of cultured fishes significant bacterial disease, fish streptococcosis cause of disease be Streptococcus iniae, The coccus of Streptococcusagalactiae, accessory mamma streptococcus, Lactococcus garvieae etc., Gram-positive, double-strand or chain lock shape.Fish chain Based on nervous symptoms, sick fish is rotated the acute case of coccus disease with C-shaped or the bending of comma sample;Chronic cases are with eye Ball is protruded, muddiness is characterized.The Ministry of Agriculture in 2008 announces No. 1125 and is classified as three class animal epidemics.Although streptococcus can be felt Contaminate various aquiculture animals and cause disease, but, there is certain selectivity for different breeding fish.The disease mostly occurs In the salmon fishes such as Tilapia mossambica, channel catfish, sweetfish, Colossoma brachypomum, the close perch of striped, the blue sub- fish of hickie, rainbow trout, barramundi, The fish such as golden head porgy, the blue sub- fish of hyoid tooth perch and wild gold ribbon, miscellaneous spot Lizardfiss, Conodon, and have no infection grass carp, carp, The cultured fishes such as silver carp, flathead, Tilapia mossambica suffers from the cardinal symptom after streptococcosis, ill fish gradually disequilibrium, have even in water Middle rolling, leaning to one side of having does circular motion;When being in a bad way, sick fish preceding on one's deathbed is spinned in the water surface or intermittence alters trip;Belly body Table has point-like or plaque haemorrhage or ulcer, and lower jaw and two gill cover lower edges have a diffusivity bleeding, liver, gall-bladder, spleen enlargement, goes out Blood, it is rotten to the corn when serious;There are ponding or yellow mucus in enteron aisle, anus is protruded;Eyeball congestion, enlargement, protrusion, serious cornea Muddiness is turned white, or even eyeball comes off.Although also thering is some medicines and antibiotic to be used to treat the nothing of Tilapia mossambica in the prior art Streptococcus lactis disease, but the drug resistance and abuse of antibiotics that are caused because of long-term use also cause harm to aquaculture, seek one Planting can prevent fish streptococcosis, will not cause the research of side effect very urgent to Rofe fish culture again.
The content of the invention
It is an object of the invention to overcome shortcoming present in prior art, there is provided a kind of reasonable recipe, prepare it is simple, A kind of composition of preventing and treating fish streptococcosis easy to use.
The composition of described a kind of preventing and treating fish streptococcosis, it is characterised in that be made up of the raw material of following weight portion:Folium artemisiae argyi 6 ~10 parts, 2~5 parts of betel nut, 6~10 parts of the coptis, 3~6 parts of Radix Glycyrrhizae, 3~6 parts of the root of large-flowered skullcap, 8~12 parts of radix bupleuri, 5~8 parts of camphorwood, 10~15 parts of Honeysuckle flower, 5~8 parts of great burdock achene.
A kind of preparation method of the composition of above-mentioned preventing and treating fish streptococcosis is:Each original is weighed by described weight portion Material, weighs herbal raw material by weight, dry, pulverize to 100 mesh or so, it is well mixed, packaging obtains final product composition.
A kind of application method of the composition for preventing and treating fish streptococcosis, it is characterised in that by composition by 0.5% ~ 0.8% ratio is made an addition in conventional feed.
A kind of above-mentioned composition material effect parsing for preventing and treating fish streptococcosis:
Folium artemisiae argyi:With antibacterial action, can significantly increase reticuloendothelial cell phagocytic function, relieving asthma, antibechic, eliminating the phlegm, antiallergy Property shock, suppress myocardial contraction, anticoagulant and high intensity and suppress platelet aggregation;
Betel nut:Excited choline receptor, resisting pathogenic microbes, anti-hypertension, anticancer;
The coptis:Heat-clearing and damp-drying drug, purging intense heat and detonicating, antibacterial action, anti-inflammatory, anti-CaM antibody;
Radix Glycyrrhizae:Anti-inflammatory, antiulcer, antianaphylaxis, anticancer, antibacterial are antiviral, promote pancreatic secretion, have suppression in vitro intestines, Regulation immunologic function;
The root of large-flowered skullcap:It is heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, antiabortive, there is inhibitory action to bacillus, coccus, infected by influenza, skin are true Bacterium;
Radix bupleuri:With anti-inflammatory, antipyretic, calm, analgesia, antibechic and anticonvulsant action;It is antiulcer, antibacterial, antiviral;
Camphorwood:Expelling wind and clearing away cold, has inhibitory action to staphylococcus aureus, Pseudomonas aeruginosa;
Honeysuckle flower:Clearing heat and detoxicating, wind-heat dissipating.It is thin with antibacterial, resisting pathogenic microbes, antitoxin, anti-inflammatory, antipyretic, promotion inflammatory Born of the same parents' phagocytic function, enhancing body's immunity effect;
Great burdock achene:Dispelling wind and heat from the body, facilitaing lung promoting eruption, subdhing swelling and detoxicating.Anti-bacteria and anti-virus;It is hypoglycemic;Step-down;Anti- ephrosis.
Beneficial effect:
1st, energy effectively preventing fish streptococcosis, reduces because fish streptococcosis is dead;
2nd, using the cooperation of Chinese herbal medicine formula, it is not likely to produce the resistance to the action of a drug;
3rd, many advantages, such as lacking with safe, residual.
Specific embodiment:
Embodiment one:
The composition of described a kind of preventing and treating fish streptococcosis, it is characterised in that be made up of the raw material of following weight portion:Folium artemisiae argyi 6 Part, 5 parts of betel nut, 9 parts of the coptis, 6 parts of Radix Glycyrrhizae, 3 parts of the root of large-flowered skullcap, 11 parts of radix bupleuri, 8 parts of camphorwood, 11 parts of Honeysuckle flower, 5 parts of great burdock achene.
Embodiment two:
The composition of described a kind of preventing and treating fish streptococcosis, it is characterised in that be made up of the raw material of following weight portion:Folium artemisiae argyi 7 Part, 4 parts of betel nut, 8 parts of the coptis, 5 parts of Radix Glycyrrhizae, 4 parts of the root of large-flowered skullcap, 10 parts of radix bupleuri, 7 parts of camphorwood, 12 parts of Honeysuckle flower, 7 parts of great burdock achene.
Embodiment three:
The composition of described a kind of preventing and treating fish streptococcosis, it is characterised in that be made up of the raw material of following weight portion:Folium artemisiae argyi 8 Part, 3 parts of betel nut, 7 parts of the coptis, 5 parts of Radix Glycyrrhizae, 5 parts of the root of large-flowered skullcap, 9 parts of radix bupleuri, 6 parts of camphorwood, 13 parts of Honeysuckle flower, 8 parts of great burdock achene.
A kind of preparation method of the composition of above-mentioned preventing and treating fish streptococcosis is:Each original is weighed by described weight portion Material, weighs herbal raw material by weight, dry, pulverize to 100 mesh or so, it is well mixed, packaging obtains final product composition.
A kind of application method of the composition for preventing and treating fish streptococcosis, it is characterised in that by composition by 0.5% ~ 0.8% ratio is made an addition in conventional feed.
Experiment effect of the invention
The tail of streptococcosis Tilapia mossambica 800 is taken, every group of 200 tails, point four ponds are placed, and the tail of disease fish 150, water depth are put into per pond 1.5 meters, control 26 DEG C or so of water temperature, pH 6~8.Blank group routine feeding, experimental group 1 uses embodiments of the invention one, real Test group 2 and use an embodiments of the invention two, experimental group 3 uses embodiments of the invention three, experimental group by the present composition In conventional feed being made an addition in 0.5% ratio.The data such as following table of record fish after 10 days:
Blank group Experimental group 1 Experimental group 2 Experimental group 3
Sick fish number 200 200 200 200
Survival number 101 178 182 185
Survival rate 50.5% 89.0% 91.0% 92.5%
The present invention has good curative effect to fish streptococcosis as can be seen from the above table.
The above, is only presently preferred embodiments of the present invention, is not the limitation for making other forms to the present invention, is appointed What those skilled in the art changed possibly also with the technology contents of the disclosure above or be modified as equivalent variations etc. Effect embodiment.But it is every without departing from technical solution of the present invention content, according to technical spirit of the invention to above example institute Any simple modification, equivalent variations and the remodeling made, still fall within the protection domain of technical solution of the present invention.

Claims (1)

1. it is a kind of prevent and treat fish streptococcosis composition, it is characterised in that be made up of the raw material of following weight portion:Folium artemisiae argyi 6~10 Part, 2~5 parts of betel nut, 6~10 parts of the coptis, 3~6 parts of Radix Glycyrrhizae, 3~6 parts of the root of large-flowered skullcap, 8~12 parts of radix bupleuri, 5~8 parts of camphorwood, mountain silver Spend 10~15 parts, 5~8 parts of great burdock achene.
CN201710126167.6A 2017-03-06 2017-03-06 A kind of composition for preventing and treating fish streptococcosis Withdrawn CN106728619A (en)

Priority Applications (1)

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CN201710126167.6A CN106728619A (en) 2017-03-06 2017-03-06 A kind of composition for preventing and treating fish streptococcosis

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CN201710126167.6A CN106728619A (en) 2017-03-06 2017-03-06 A kind of composition for preventing and treating fish streptococcosis

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111467386A (en) * 2020-05-25 2020-07-31 邓军龙 Antibacterial and detoxifying traditional Chinese medicine purification composition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103844143A (en) * 2014-03-11 2014-06-11 广西大学 Chinese herbal compound feed additive preventing streptococcicosis for tilapia mossambica
CN106389683A (en) * 2016-12-18 2017-02-15 长沙瑞多康生物科技有限公司 Composition capable of preventing fish streptococcicosis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103844143A (en) * 2014-03-11 2014-06-11 广西大学 Chinese herbal compound feed additive preventing streptococcicosis for tilapia mossambica
CN106389683A (en) * 2016-12-18 2017-02-15 长沙瑞多康生物科技有限公司 Composition capable of preventing fish streptococcicosis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111467386A (en) * 2020-05-25 2020-07-31 邓军龙 Antibacterial and detoxifying traditional Chinese medicine purification composition

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Application publication date: 20170531