CN106728321A - A kind of eye ointment and preparation method thereof - Google Patents

A kind of eye ointment and preparation method thereof Download PDF

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CN106728321A
CN106728321A CN201611128195.3A CN201611128195A CN106728321A CN 106728321 A CN106728321 A CN 106728321A CN 201611128195 A CN201611128195 A CN 201611128195A CN 106728321 A CN106728321 A CN 106728321A
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parts
eye
weight
ointment
eye ointment
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陈忠燕
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07Retinol compounds, e.g. vitamin A
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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Abstract

The present invention relates to a kind of eye ointment and preparation method thereof, eye ointment is by pearl powder, rhizoma atractylodis, the seed of feather cockscomb, peppermint, purslane, radix rehmanniae recen, black soya bean, lotus leaf, feverfew, Semen Leonuri, rosemary, vitamin A, lutein, eye pasting substrate, glycerine, milk composition, eye pasting substrate is made up of albolene, atoleine and lanolin.Eye ointment formula of the invention is reasonable, can clear liver and improve vision, and kopiopia is alleviated in moisturizing moisturizing, and easy to use, effect is good.The preparation method is simple to operate, and inexpensive drug effect is high, and poison is secondary small pollution-free.

Description

A kind of eye ointment and preparation method thereof
Technical field
The present invention relates to a kind of eye ointment and preparation method thereof.
Background technology
The use kopiopia problem of current people is increasingly severe, and eye dry eyes are puckery, serious the problems such as eye water shortage inflammation, due to People need long-term opposite computer work mostly, like playing mobile phone, see that TV is more exacerbated and use kopiopia.For eye fatigue Alleviation method, of all kinds, masses receive to be many rests;Replenishing vitamins;Using eye drops or eye ointment and do eye exercises. It is simply again convenient using eye drops and eye ointment, but general eyedrops and eye ointment are all Western medicine, and long-term use is unfavorable to body, more Pointed out come more reports, long-term use or excessively use eyedrops, make eyes capacity of self-regulation worse and worse, medicine is got over More to rely on, What is more causes blindness.
Existing pure Chinese medicine draft eye ointment matches imperfection, effect when influence is used.
The content of the invention
To solve the deficiency of the ointment for alleviating eye strain in the prior art, the technical problem to be solved in the present invention is to provide A kind of safety has no side effect, eye ointment of the pure draft without hormone.On the other hand, another technical problem to be solved of the invention is There is provided a kind of safety to have no side effect, the preparation method of eye ointment of the pure draft without hormone.
The present invention provides following technical scheme:
A kind of eye ointment, is made up of the raw material of following portions by weight:Pearl powder 8-14 parts, rhizoma atractylodis 5-9 parts, seed of feather cockscomb 4-8 parts, peppermint 4-8 parts, purslane 6-10 parts, radix rehmanniae recen 6-12 parts, black soya bean 6-10 parts, lotus leaf 6-8 parts, feverfew 10-20 parts, Semen Leonuri 4-8 Part, rosemary 10-18 parts, vitamin A 0.02-0.08 parts, lutein 0.02-0.06 parts, eye pasting substrate 800-1600 parts, glycerine 2-6 parts, milk 4-8 parts, the eye pasting substrate is made up of albolene, atoleine and lanolin.
Preferably, the raw material composition of the eye ointment following portions by weight:11 parts of pearl powder, 7 parts of rhizoma atractylodis, 6 parts of the seed of feather cockscomb is thin 6 parts of lotus, 8 parts of purslane, 9 parts of radix rehmanniae recen, 8 parts of black soya bean, 7 parts of lotus leaf, 15 parts of feverfew, 6 parts of Semen Leonuri, 14 parts of rosemary, dimension Raw A0.05 parts of element, 0.03 part of lutein, eye pasting substrate 1200,4 parts of glycerine, 6 parts of milk, the eye pasting substrate by albolene, Atoleine and lanolin are constituted.
Preferably, the eye pasting substrate by following weight than raw material constitute, albolene:Atoleine:Lanolin=6: 1:1。
A kind of preparation method of eye ointment is provided, step is as follows:The first step, by rhizoma atractylodis, the seed of feather cockscomb, peppermint, purslane, the dried rhizome of rehmannia Huang, black soya bean, lotus leaf, feverfew, Semen Leonuri, rosemary is weighed, cleans, sterilizes, dried by weight, adds raw material 4-9 Times ethanol invades bubble 4-10 hour, and heating is decocted 1-2 hours, is filtered, and obtains the dregs of a decoction 1 and filtrate 1;The dregs of a decoction 1 add 6-10 times of decocting to boil 0.5-2 hours, filter to obtain the dregs of a decoction 2 and filtrate 2, filtrate 1 and filtrate are 2-in-1 and be concentrated into relative density for 1.01-1.03, must concentrate Liquid;Second step, matrix is configured to by proportioning by albolene, liquid paraffin, lanolin, is heated to 85-100 DEG C, 60- to be cooled to At 70 DEG C, above-mentioned concentrate and proportioning parts by weight pearl powder, vitamin A, lutein, glycerine, milk, mixing are added, obtain eye Cream.
Eye ointment is mainly made up of pure Chinese herbal medicine, addition eye pasting substrate, glycerine, milk, vitamin A and lutein, natural nothing Stimulate, it is safe and reliable.Wherein Chinese herbal medicine formula, scientific and reasonable compatibility, it then follows " monarch, minister, help, make " principle, with pearl powder, feverfew Flower is monarch drug in a prescription, and to clear liver and improve vision, treatment red eye, swell pain, eyes are dim-sighted, with Semen Leonuri, the seed of feather cockscomb, purslane, radix rehmanniae recen, black soya bean It is ministerial drug, can clears liver and improve vision, antibacterial, clearing heat and detoxicating, swelling and pain relieving, with rhizoma atractylodis, peppermint, lotus leaf, rosemary as adjuvant, cool blood Hemostasis, coordinating the drug actions of a prescription, reasonable compatibility is realized alleviating eye dryness, and the dry and astringent red and swollen pharmacological function effect of prevention eye reaches slow Solve the purpose of eye strain.Eye ointment add milk, glycerine can replenishing water and preserving moisture, add lutein and vitamin A to protect eyesight, be confused Repeatedly perfume (or spice) can refresh the mind, and have stronger astriction to skin, stimulate circulation, and mitigate kopiopia.
Beneficial effect:Eye ointment energy rapid osmotic skin of the invention, symptom position of going directly, nutrition needed for supplement eye;It is slow Solution eye dry eyes are puckery, and the easypro network that stimulates the menstrual flow promoting blood circulation and removing blood stasis, detumescence relieves the pain, and expansion local vascular increases blood flow, clears liver and improve vision;Improve eye Portion's endocrine and metabolism, strengthen light sensation ability, adjust diopter, alleviate eye strain;Pure draft does not stimulate without hormone. Coordinate ocular region massaging, it is better.Formula more rationally, alleviates kopiopia, and improvement eye dry eyes are puckery, the disease such as inflamed water shortage of eye Shape is better.
The preparation method is applied to this eye ointment, and simple to operate, easy to use, without any side effects, external application is safe and reliable, Make drug effect more preferable.
Specific embodiment
With reference to specific embodiment, the present invention is furture elucidated, it should be understood that following specific embodiments are only used for The bright present invention rather than limitation the scope of the present invention.
A kind of eye ointment of embodiment 1, is made up of the raw material of following portions by weight:8 parts of pearl powder, 5 parts of rhizoma atractylodis, 4 parts of the seed of feather cockscomb, 4 parts of peppermint, 6 parts of purslane, 6 parts of radix rehmanniae recen, 6 parts of black soya bean, 6 parts of lotus leaf, 10 parts of feverfew, 4 parts of Semen Leonuri, 10 parts of rosemary, 0.02 part of vitamin A, 0.02 part of lutein, 800 parts of eye pasting substrate, 2 parts of glycerine, 4 parts of milk, eye pasting substrate by albolene, The part by weight such as atoleine and lanolin is constituted.
Preparation method, step is as follows:
The first step, weighs 5 parts of rhizoma atractylodis, 4 parts of the seed of feather cockscomb, 4 parts of peppermint, 6 parts of purslane, 6 parts of radix rehmanniae recen, black soya bean 6 by weight Part, 6 parts of lotus leaf, 10 parts of feverfew, 4 parts of Semen Leonuri, 10 parts of rosemary is cleaned, sterilizes, dried, and adds 4 times of ethanol of raw material to invade When steeping 4, heating is decocted 1 hour, and filtering obtains the dregs of a decoction 1 and filtrate 1;The dregs of a decoction 1 add 6 times of decoctings to boil 0.5 hour, filter to obtain the dregs of a decoction 2 With filtrate 2, filtrate 1 and filtrate are 2-in-1 and be concentrated into relative density for 1.01, obtain concentrate;Second step, albolene, liquid stone The part by weight such as wax, lanolin are configured to matrix, are heated to 85 DEG C, when being cooled to 60 DEG C, add concentrate, the proportioning of the first step The pearl powder of parts by weight, vitamin A, lutein, glycerine, milk, mixing, obtain eye ointment.
A kind of eye ointment of embodiment 2, is made up of the raw material of following portions by weight:14 parts of pearl powder, 9 parts of rhizoma atractylodis, the seed of feather cockscomb 8 Part, 8 parts of peppermint, 10 parts of purslane, 12 parts of radix rehmanniae recen, 10 parts of black soya bean, 8 parts of lotus leaf, 20 parts of feverfew, 8 parts of Semen Leonuri, rosemary 18 parts, 0.08 part of vitamin A, 0.06 part of lutein, 1600 parts of eye pasting substrate, 6 parts of glycerine, 8 parts of milk, eye pasting substrate is by white all Intellectual circle, atoleine and lanolin are 1 by ratio of weight and the number of copies:1.5:2 compositions.
Preparation method, step is as follows:
The first step, weighs 9 parts of rhizoma atractylodis, 8 parts of the seed of feather cockscomb, 8 parts of peppermint, 10 parts of purslane, 12 parts of radix rehmanniae recen, black soya bean by weight 10 parts, 8 parts of lotus leaf, 20 parts of feverfew, 8 parts of Semen Leonuri, 18 parts of rosemary is cleaned, sterilizes, dried, and adds 9 times of ethanol of raw material Invade bubble 10 hours, heating is decocted 2 hours, filtering obtains the dregs of a decoction 1 and filtrate 1;The dregs of a decoction 1 add 10 times of decoctings to boil 2 hours, filter The dregs of a decoction 2 and filtrate 2, filtrate 1 and filtrate are 2-in-1 and be concentrated into relative density for 1.03, obtain concentrate;Second step, will be white by proportioning Vaseline, liquid paraffin, lanolin are configured to matrix, are heated to 100 DEG C, when being cooled to 70 DEG C, add first step concentrate, match somebody with somebody The pearl powder of weight/power ratio number, vitamin A, lutein, glycerine, milk, obtain eye ointment.
A kind of eye ointment of embodiment 3, is made up of the raw material of following portions by weight:11 parts of pearl powder, 7 parts of rhizoma atractylodis, the seed of feather cockscomb 6 Part, 6 parts of peppermint, 8 parts of purslane, 9 parts of radix rehmanniae recen, 8 parts of black soya bean, 7 parts of lotus leaf, 15 parts of feverfew, 6 parts of Semen Leonuri, rosemary 14 Part, 0.05 part of vitamin A, 0.03 part of lutein, eye pasting substrate 1200,4 parts of glycerine, 6 parts of milk, eye pasting substrate is by Bai Fanshi The white vaseline by weight of woods, atoleine and lanolin:Atoleine:Lanolin=6:1:1 composition.
Preparation method, step is as follows:
The first step, weighs 9 parts of rhizoma atractylodis, 8 parts of the seed of feather cockscomb, 8 parts of peppermint, 10 parts of purslane, 12 parts of radix rehmanniae recen, black soya bean by weight 10 parts, 8 parts of lotus leaf, 20 parts of feverfew, 8 parts of Semen Leonuri, 18 parts of rosemary is cleaned, sterilizes, dried, and adds 6 times of ethanol of raw material Invade bubble 7 hours, heating is decocted 1.5 hours, filtering obtains the dregs of a decoction 1 and filtrate 1;The dregs of a decoction 1 add 7 times of decoctings to boil 1 hour, filter The dregs of a decoction 2 and filtrate 2, filtrate 1 and filtrate are 2-in-1 and be concentrated into relative density for 1.02, obtain concentrate;Second step, will be white by proportioning Vaseline, liquid paraffin, lanolin are configured to matrix, are heated to 95 DEG C, when being cooled to 65 DEG C, add concentrate, with weight/power ratio The pearl powder of number, vitamin A, lutein, glycerine, milk, obtain eye ointment.
Clinical test:
Randomly selecting 300 asthenopes carries out clinical test, and patient age is in 14-50 Sui, average age 30 years old, by patient It is divided into 3 groups, respectively using the eye ointment in embodiment 1 to 3, application method is that twice a day, sooner or later respectively once, eye strain is tight Painting can be added during weight once.A course for the treatment of on the seven.
Criterion of therapeutical effect is:Recovery from illness, symptom is wholly absent, and eye is not tired, not engorgement pain, and eye dry eyes are not puckery;Take a turn for the better, disease Shape disappears substantially, and kopiopia mitigates, and eye dry eyes are puckery etc., and symptom all mitigates;Invalid, all symptoms are without improvement.
Clinical effectiveness:
Embodiment 1:Cure rate 62%, improvement rate 37%, inefficiency 1%, the average improvement time be using ointment two days later.
Embodiment 1:Cure rate 64%, improvement rate 34%, inefficiency 2%, the average improvement time be using ointment two days later.
Embodiment 3:Cure rate 70%, improvement rate 29%, inefficiency 1%, the average improvement time be using ointment two days later.
All patients are effectively treated, and are had no adverse reaction during medication, and effective percentage reaches more than 98%, take a turn for the better fast, treat Effect is notable, safe and reliable, non-stimulated and adverse reaction.
Clinical exemplary embodiments:
1. Lee so-and-so, 15 years old, man, student.After eye's fatigue, immediately using this ointment, the same day has taken a turn for the better, and eye dry eyes are puckery Problem is pulled up a horse and is eased, and is fully recovered two days later.
2. leaf so-and-so, 28 years old, female, white collar.Patient because to computer work, eye strain happens occasionally for a long time, eye dry eyes Puckery problem is serious, using one day after, symptom has relaxed, and is taken a turn for the better after a course for the treatment of.
3. certain is permitted, man, 34 years old, white collar.Eye's fatigue more than two days, using ointment, using symptom after a day Relax, taken a turn for the better after three days.
Technological means disclosed in the present invention program is not limited only to the technological means disclosed in above-mentioned implementation method, also includes Constituted technical scheme is combined by above technical characteristic.It should be pointed out that for those skilled in the art For, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications are also considered as Protection scope of the present invention.

Claims (4)

1. a kind of eye ointment, it is characterised in that be made up of the raw material of following portions by weight:Pearl powder 8-14 parts, rhizoma atractylodis 5-9 parts, feather cockscomb It is sub- 4-8 parts, peppermint 4-8 parts, purslane 6-10 parts, radix rehmanniae recen 6-12 parts, black soya bean 6-10 parts, lotus leaf 6-8 parts, feverfew 10-20 Part, Semen Leonuri 4-8 parts, rosemary 10-18 parts, vitamin A 0.02-0.08 parts, lutein 0.02-0.06 parts, eye pasting substrate 800-1600 parts, glycerine 2-6 parts, milk 4-8 parts, the eye pasting substrate is made up of albolene, atoleine and lanolin.
2. a kind of eye ointment as claimed in claim 1, it is characterised in that be made up of the raw material of following portions by weight:Pearl powder 11 Part, 7 parts of rhizoma atractylodis, 6 parts of the seed of feather cockscomb, 6 parts of peppermint, 8 parts of purslane, 9 parts of radix rehmanniae recen, 8 parts of black soya bean, 7 parts of lotus leaf, 15 parts of feverfew, 6 parts of Semen Leonuri, 14 parts of rosemary, 0.05 part of vitamin A, 0.03 part of lutein, eye pasting substrate 1200,4 parts of glycerine, 6 parts of milk, The eye pasting substrate is made up of albolene, atoleine and lanolin.
3. a kind of eye ointment as claimed in claim 1 or 2, it is characterised in that the eye pasting substrate by following weight than raw material group Into albolene:Atoleine:Lanolin=6:1:1.
4. a kind of preparation method for realizing the eye ointment described in claim 1, it is characterised in that comprise the following steps:First Step, by rhizoma atractylodis, the seed of feather cockscomb, peppermint, purslane, radix rehmanniae recen, black soya bean, lotus leaf, feverfew, Semen Leonuri, rosemary is by weight Weigh, clean, sterilize, dry, add 4-9 times of ethanol of raw material to invade bubble 4-10 hours, heating is decocted 1-2 hours, filtering obtains medicine Slag 1 and filtrate 1;The dregs of a decoction 1 add 6-10 times of decocting to boil 0.5-2 hours, filter to obtain the dregs of a decoction 2 and filtrate 2, and filtrate 1 and filtrate are 2-in-1 simultaneously Relative density is concentrated into for 1.01-1.03, concentrate is obtained;Second step, is matched somebody with somebody albolene, liquid paraffin, lanolin by proportioning Matrix is made, 85-100 DEG C is heated to, when being cooled to 60-70 DEG C, above-mentioned concentrate and proportioning parts by weight pearl powder, dimension is added Raw element A, lutein, glycerine, milk, mixing obtain eye ointment.
CN201611128195.3A 2016-12-09 2016-12-09 A kind of eye ointment and preparation method thereof Withdrawn CN106728321A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107157923A (en) * 2017-07-03 2017-09-15 武汉瑞福宁科技有限公司 A kind of zoopery protection eye ointment and its application device
CN115444803A (en) * 2022-09-13 2022-12-09 武汉洁宜生物科技有限公司 Antibacterial moisturizing medical eye protection patch and preparation method thereof
CN116327846A (en) * 2023-05-15 2023-06-27 普润德百目通(北京)科技有限公司 Traditional Chinese medicine eye ointment for nourishing blood and improving eyesight and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN105833094A (en) * 2016-05-24 2016-08-10 柳晖 Traditional Chinese medicine composition for treating trachoma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105833094A (en) * 2016-05-24 2016-08-10 柳晖 Traditional Chinese medicine composition for treating trachoma

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107157923A (en) * 2017-07-03 2017-09-15 武汉瑞福宁科技有限公司 A kind of zoopery protection eye ointment and its application device
CN115444803A (en) * 2022-09-13 2022-12-09 武汉洁宜生物科技有限公司 Antibacterial moisturizing medical eye protection patch and preparation method thereof
CN116327846A (en) * 2023-05-15 2023-06-27 普润德百目通(北京)科技有限公司 Traditional Chinese medicine eye ointment for nourishing blood and improving eyesight and preparation method thereof
CN116327846B (en) * 2023-05-15 2023-11-03 普润德百目通(北京)科技有限公司 Traditional Chinese medicine eye ointment for nourishing blood and improving eyesight and preparation method thereof

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