CN106728321A - A kind of eye ointment and preparation method thereof - Google Patents
A kind of eye ointment and preparation method thereof Download PDFInfo
- Publication number
- CN106728321A CN106728321A CN201611128195.3A CN201611128195A CN106728321A CN 106728321 A CN106728321 A CN 106728321A CN 201611128195 A CN201611128195 A CN 201611128195A CN 106728321 A CN106728321 A CN 106728321A
- Authority
- CN
- China
- Prior art keywords
- parts
- eye
- weight
- ointment
- eye ointment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003885 eye ointment Substances 0.000 title claims abstract description 31
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 30
- 239000000758 substrate Substances 0.000 claims abstract description 19
- 239000004166 Lanolin Substances 0.000 claims abstract description 16
- 229940039717 lanolin Drugs 0.000 claims abstract description 16
- 235000019388 lanolin Nutrition 0.000 claims abstract description 16
- 240000002853 Nelumbo nucifera Species 0.000 claims abstract description 15
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims abstract description 15
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims abstract description 15
- 235000011187 glycerol Nutrition 0.000 claims abstract description 15
- 229960005375 lutein Drugs 0.000 claims abstract description 15
- 239000001656 lutein Substances 0.000 claims abstract description 15
- 235000012680 lutein Nutrition 0.000 claims abstract description 15
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 claims abstract description 15
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 claims abstract description 15
- 239000008267 milk Substances 0.000 claims abstract description 15
- 235000013336 milk Nutrition 0.000 claims abstract description 15
- 210000004080 milk Anatomy 0.000 claims abstract description 15
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 claims abstract description 15
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 claims abstract description 15
- 240000008365 Celosia argentea Species 0.000 claims abstract description 14
- 235000000722 Celosia argentea Nutrition 0.000 claims abstract description 14
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 claims abstract description 14
- 244000192528 Chrysanthemum parthenium Species 0.000 claims abstract description 14
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 claims abstract description 14
- 244000068988 Glycine max Species 0.000 claims abstract description 14
- 235000010469 Glycine max Nutrition 0.000 claims abstract description 14
- 235000001855 Portulaca oleracea Nutrition 0.000 claims abstract description 14
- 244000178231 Rosmarinus officinalis Species 0.000 claims abstract description 14
- 235000008384 feverfew Nutrition 0.000 claims abstract description 14
- 239000000843 powder Substances 0.000 claims abstract description 14
- 210000000582 semen Anatomy 0.000 claims abstract description 14
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 13
- 244000246386 Mentha pulegium Species 0.000 claims abstract description 13
- 235000016257 Mentha pulegium Nutrition 0.000 claims abstract description 13
- 235000004357 Mentha x piperita Nutrition 0.000 claims abstract description 13
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims abstract description 13
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 13
- 235000001050 hortel pimenta Nutrition 0.000 claims abstract description 13
- 235000019155 vitamin A Nutrition 0.000 claims abstract description 13
- 239000011719 vitamin A Substances 0.000 claims abstract description 13
- 229940045997 vitamin a Drugs 0.000 claims abstract description 13
- 244000234609 Portulaca oleracea Species 0.000 claims abstract 4
- 239000000706 filtrate Substances 0.000 claims description 20
- 239000002994 raw material Substances 0.000 claims description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- 239000012141 concentrate Substances 0.000 claims description 10
- 239000003814 drug Substances 0.000 claims description 8
- 238000010438 heat treatment Methods 0.000 claims description 5
- 239000011159 matrix material Substances 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 4
- 229940057995 liquid paraffin Drugs 0.000 claims description 4
- 239000002893 slag Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 5
- 230000004438 eyesight Effects 0.000 abstract description 5
- 210000004185 liver Anatomy 0.000 abstract description 4
- 239000000203 mixture Substances 0.000 abstract description 4
- 230000000857 drug effect Effects 0.000 abstract description 2
- 230000003020 moisturizing effect Effects 0.000 abstract 2
- 239000002574 poison Substances 0.000 abstract 1
- 231100000614 poison Toxicity 0.000 abstract 1
- 241000219304 Portulacaceae Species 0.000 description 10
- 230000006872 improvement Effects 0.000 description 10
- 206010013774 Dry eye Diseases 0.000 description 8
- 208000003464 asthenopia Diseases 0.000 description 8
- 208000003556 Dry Eye Syndromes Diseases 0.000 description 7
- 239000002674 ointment Substances 0.000 description 6
- 208000024891 symptom Diseases 0.000 description 6
- 229940079593 drug Drugs 0.000 description 4
- 239000003889 eye drop Substances 0.000 description 4
- 229940012356 eye drops Drugs 0.000 description 4
- 229960005150 glycerol Drugs 0.000 description 4
- 239000005556 hormone Substances 0.000 description 3
- 229940088597 hormone Drugs 0.000 description 3
- 230000007774 longterm Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 241000721047 Danaus plexippus Species 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 229940099259 vaseline Drugs 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 201000004569 Blindness Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 241000405414 Rehmannia Species 0.000 description 1
- 241000593989 Scardinius erythrophthalmus Species 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 238000010422 painting Methods 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 239000003871 white petrolatum Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of eye ointment and preparation method thereof, eye ointment is by pearl powder, rhizoma atractylodis, the seed of feather cockscomb, peppermint, purslane, radix rehmanniae recen, black soya bean, lotus leaf, feverfew, Semen Leonuri, rosemary, vitamin A, lutein, eye pasting substrate, glycerine, milk composition, eye pasting substrate is made up of albolene, atoleine and lanolin.Eye ointment formula of the invention is reasonable, can clear liver and improve vision, and kopiopia is alleviated in moisturizing moisturizing, and easy to use, effect is good.The preparation method is simple to operate, and inexpensive drug effect is high, and poison is secondary small pollution-free.
Description
Technical field
The present invention relates to a kind of eye ointment and preparation method thereof.
Background technology
The use kopiopia problem of current people is increasingly severe, and eye dry eyes are puckery, serious the problems such as eye water shortage inflammation, due to
People need long-term opposite computer work mostly, like playing mobile phone, see that TV is more exacerbated and use kopiopia.For eye fatigue
Alleviation method, of all kinds, masses receive to be many rests;Replenishing vitamins;Using eye drops or eye ointment and do eye exercises.
It is simply again convenient using eye drops and eye ointment, but general eyedrops and eye ointment are all Western medicine, and long-term use is unfavorable to body, more
Pointed out come more reports, long-term use or excessively use eyedrops, make eyes capacity of self-regulation worse and worse, medicine is got over
More to rely on, What is more causes blindness.
Existing pure Chinese medicine draft eye ointment matches imperfection, effect when influence is used.
The content of the invention
To solve the deficiency of the ointment for alleviating eye strain in the prior art, the technical problem to be solved in the present invention is to provide
A kind of safety has no side effect, eye ointment of the pure draft without hormone.On the other hand, another technical problem to be solved of the invention is
There is provided a kind of safety to have no side effect, the preparation method of eye ointment of the pure draft without hormone.
The present invention provides following technical scheme:
A kind of eye ointment, is made up of the raw material of following portions by weight:Pearl powder 8-14 parts, rhizoma atractylodis 5-9 parts, seed of feather cockscomb 4-8 parts, peppermint
4-8 parts, purslane 6-10 parts, radix rehmanniae recen 6-12 parts, black soya bean 6-10 parts, lotus leaf 6-8 parts, feverfew 10-20 parts, Semen Leonuri 4-8
Part, rosemary 10-18 parts, vitamin A 0.02-0.08 parts, lutein 0.02-0.06 parts, eye pasting substrate 800-1600 parts, glycerine
2-6 parts, milk 4-8 parts, the eye pasting substrate is made up of albolene, atoleine and lanolin.
Preferably, the raw material composition of the eye ointment following portions by weight:11 parts of pearl powder, 7 parts of rhizoma atractylodis, 6 parts of the seed of feather cockscomb is thin
6 parts of lotus, 8 parts of purslane, 9 parts of radix rehmanniae recen, 8 parts of black soya bean, 7 parts of lotus leaf, 15 parts of feverfew, 6 parts of Semen Leonuri, 14 parts of rosemary, dimension
Raw A0.05 parts of element, 0.03 part of lutein, eye pasting substrate 1200,4 parts of glycerine, 6 parts of milk, the eye pasting substrate by albolene,
Atoleine and lanolin are constituted.
Preferably, the eye pasting substrate by following weight than raw material constitute, albolene:Atoleine:Lanolin=6:
1:1。
A kind of preparation method of eye ointment is provided, step is as follows:The first step, by rhizoma atractylodis, the seed of feather cockscomb, peppermint, purslane, the dried rhizome of rehmannia
Huang, black soya bean, lotus leaf, feverfew, Semen Leonuri, rosemary is weighed, cleans, sterilizes, dried by weight, adds raw material 4-9
Times ethanol invades bubble 4-10 hour, and heating is decocted 1-2 hours, is filtered, and obtains the dregs of a decoction 1 and filtrate 1;The dregs of a decoction 1 add 6-10 times of decocting to boil
0.5-2 hours, filter to obtain the dregs of a decoction 2 and filtrate 2, filtrate 1 and filtrate are 2-in-1 and be concentrated into relative density for 1.01-1.03, must concentrate
Liquid;Second step, matrix is configured to by proportioning by albolene, liquid paraffin, lanolin, is heated to 85-100 DEG C, 60- to be cooled to
At 70 DEG C, above-mentioned concentrate and proportioning parts by weight pearl powder, vitamin A, lutein, glycerine, milk, mixing are added, obtain eye
Cream.
Eye ointment is mainly made up of pure Chinese herbal medicine, addition eye pasting substrate, glycerine, milk, vitamin A and lutein, natural nothing
Stimulate, it is safe and reliable.Wherein Chinese herbal medicine formula, scientific and reasonable compatibility, it then follows " monarch, minister, help, make " principle, with pearl powder, feverfew
Flower is monarch drug in a prescription, and to clear liver and improve vision, treatment red eye, swell pain, eyes are dim-sighted, with Semen Leonuri, the seed of feather cockscomb, purslane, radix rehmanniae recen, black soya bean
It is ministerial drug, can clears liver and improve vision, antibacterial, clearing heat and detoxicating, swelling and pain relieving, with rhizoma atractylodis, peppermint, lotus leaf, rosemary as adjuvant, cool blood
Hemostasis, coordinating the drug actions of a prescription, reasonable compatibility is realized alleviating eye dryness, and the dry and astringent red and swollen pharmacological function effect of prevention eye reaches slow
Solve the purpose of eye strain.Eye ointment add milk, glycerine can replenishing water and preserving moisture, add lutein and vitamin A to protect eyesight, be confused
Repeatedly perfume (or spice) can refresh the mind, and have stronger astriction to skin, stimulate circulation, and mitigate kopiopia.
Beneficial effect:Eye ointment energy rapid osmotic skin of the invention, symptom position of going directly, nutrition needed for supplement eye;It is slow
Solution eye dry eyes are puckery, and the easypro network that stimulates the menstrual flow promoting blood circulation and removing blood stasis, detumescence relieves the pain, and expansion local vascular increases blood flow, clears liver and improve vision;Improve eye
Portion's endocrine and metabolism, strengthen light sensation ability, adjust diopter, alleviate eye strain;Pure draft does not stimulate without hormone.
Coordinate ocular region massaging, it is better.Formula more rationally, alleviates kopiopia, and improvement eye dry eyes are puckery, the disease such as inflamed water shortage of eye
Shape is better.
The preparation method is applied to this eye ointment, and simple to operate, easy to use, without any side effects, external application is safe and reliable,
Make drug effect more preferable.
Specific embodiment
With reference to specific embodiment, the present invention is furture elucidated, it should be understood that following specific embodiments are only used for
The bright present invention rather than limitation the scope of the present invention.
A kind of eye ointment of embodiment 1, is made up of the raw material of following portions by weight:8 parts of pearl powder, 5 parts of rhizoma atractylodis, 4 parts of the seed of feather cockscomb,
4 parts of peppermint, 6 parts of purslane, 6 parts of radix rehmanniae recen, 6 parts of black soya bean, 6 parts of lotus leaf, 10 parts of feverfew, 4 parts of Semen Leonuri, 10 parts of rosemary,
0.02 part of vitamin A, 0.02 part of lutein, 800 parts of eye pasting substrate, 2 parts of glycerine, 4 parts of milk, eye pasting substrate by albolene,
The part by weight such as atoleine and lanolin is constituted.
Preparation method, step is as follows:
The first step, weighs 5 parts of rhizoma atractylodis, 4 parts of the seed of feather cockscomb, 4 parts of peppermint, 6 parts of purslane, 6 parts of radix rehmanniae recen, black soya bean 6 by weight
Part, 6 parts of lotus leaf, 10 parts of feverfew, 4 parts of Semen Leonuri, 10 parts of rosemary is cleaned, sterilizes, dried, and adds 4 times of ethanol of raw material to invade
When steeping 4, heating is decocted 1 hour, and filtering obtains the dregs of a decoction 1 and filtrate 1;The dregs of a decoction 1 add 6 times of decoctings to boil 0.5 hour, filter to obtain the dregs of a decoction 2
With filtrate 2, filtrate 1 and filtrate are 2-in-1 and be concentrated into relative density for 1.01, obtain concentrate;Second step, albolene, liquid stone
The part by weight such as wax, lanolin are configured to matrix, are heated to 85 DEG C, when being cooled to 60 DEG C, add concentrate, the proportioning of the first step
The pearl powder of parts by weight, vitamin A, lutein, glycerine, milk, mixing, obtain eye ointment.
A kind of eye ointment of embodiment 2, is made up of the raw material of following portions by weight:14 parts of pearl powder, 9 parts of rhizoma atractylodis, the seed of feather cockscomb 8
Part, 8 parts of peppermint, 10 parts of purslane, 12 parts of radix rehmanniae recen, 10 parts of black soya bean, 8 parts of lotus leaf, 20 parts of feverfew, 8 parts of Semen Leonuri, rosemary
18 parts, 0.08 part of vitamin A, 0.06 part of lutein, 1600 parts of eye pasting substrate, 6 parts of glycerine, 8 parts of milk, eye pasting substrate is by white all
Intellectual circle, atoleine and lanolin are 1 by ratio of weight and the number of copies:1.5:2 compositions.
Preparation method, step is as follows:
The first step, weighs 9 parts of rhizoma atractylodis, 8 parts of the seed of feather cockscomb, 8 parts of peppermint, 10 parts of purslane, 12 parts of radix rehmanniae recen, black soya bean by weight
10 parts, 8 parts of lotus leaf, 20 parts of feverfew, 8 parts of Semen Leonuri, 18 parts of rosemary is cleaned, sterilizes, dried, and adds 9 times of ethanol of raw material
Invade bubble 10 hours, heating is decocted 2 hours, filtering obtains the dregs of a decoction 1 and filtrate 1;The dregs of a decoction 1 add 10 times of decoctings to boil 2 hours, filter
The dregs of a decoction 2 and filtrate 2, filtrate 1 and filtrate are 2-in-1 and be concentrated into relative density for 1.03, obtain concentrate;Second step, will be white by proportioning
Vaseline, liquid paraffin, lanolin are configured to matrix, are heated to 100 DEG C, when being cooled to 70 DEG C, add first step concentrate, match somebody with somebody
The pearl powder of weight/power ratio number, vitamin A, lutein, glycerine, milk, obtain eye ointment.
A kind of eye ointment of embodiment 3, is made up of the raw material of following portions by weight:11 parts of pearl powder, 7 parts of rhizoma atractylodis, the seed of feather cockscomb 6
Part, 6 parts of peppermint, 8 parts of purslane, 9 parts of radix rehmanniae recen, 8 parts of black soya bean, 7 parts of lotus leaf, 15 parts of feverfew, 6 parts of Semen Leonuri, rosemary 14
Part, 0.05 part of vitamin A, 0.03 part of lutein, eye pasting substrate 1200,4 parts of glycerine, 6 parts of milk, eye pasting substrate is by Bai Fanshi
The white vaseline by weight of woods, atoleine and lanolin:Atoleine:Lanolin=6:1:1 composition.
Preparation method, step is as follows:
The first step, weighs 9 parts of rhizoma atractylodis, 8 parts of the seed of feather cockscomb, 8 parts of peppermint, 10 parts of purslane, 12 parts of radix rehmanniae recen, black soya bean by weight
10 parts, 8 parts of lotus leaf, 20 parts of feverfew, 8 parts of Semen Leonuri, 18 parts of rosemary is cleaned, sterilizes, dried, and adds 6 times of ethanol of raw material
Invade bubble 7 hours, heating is decocted 1.5 hours, filtering obtains the dregs of a decoction 1 and filtrate 1;The dregs of a decoction 1 add 7 times of decoctings to boil 1 hour, filter
The dregs of a decoction 2 and filtrate 2, filtrate 1 and filtrate are 2-in-1 and be concentrated into relative density for 1.02, obtain concentrate;Second step, will be white by proportioning
Vaseline, liquid paraffin, lanolin are configured to matrix, are heated to 95 DEG C, when being cooled to 65 DEG C, add concentrate, with weight/power ratio
The pearl powder of number, vitamin A, lutein, glycerine, milk, obtain eye ointment.
Clinical test:
Randomly selecting 300 asthenopes carries out clinical test, and patient age is in 14-50 Sui, average age 30 years old, by patient
It is divided into 3 groups, respectively using the eye ointment in embodiment 1 to 3, application method is that twice a day, sooner or later respectively once, eye strain is tight
Painting can be added during weight once.A course for the treatment of on the seven.
Criterion of therapeutical effect is:Recovery from illness, symptom is wholly absent, and eye is not tired, not engorgement pain, and eye dry eyes are not puckery;Take a turn for the better, disease
Shape disappears substantially, and kopiopia mitigates, and eye dry eyes are puckery etc., and symptom all mitigates;Invalid, all symptoms are without improvement.
Clinical effectiveness:
Embodiment 1:Cure rate 62%, improvement rate 37%, inefficiency 1%, the average improvement time be using ointment two days later.
Embodiment 1:Cure rate 64%, improvement rate 34%, inefficiency 2%, the average improvement time be using ointment two days later.
Embodiment 3:Cure rate 70%, improvement rate 29%, inefficiency 1%, the average improvement time be using ointment two days later.
All patients are effectively treated, and are had no adverse reaction during medication, and effective percentage reaches more than 98%, take a turn for the better fast, treat
Effect is notable, safe and reliable, non-stimulated and adverse reaction.
Clinical exemplary embodiments:
1. Lee so-and-so, 15 years old, man, student.After eye's fatigue, immediately using this ointment, the same day has taken a turn for the better, and eye dry eyes are puckery
Problem is pulled up a horse and is eased, and is fully recovered two days later.
2. leaf so-and-so, 28 years old, female, white collar.Patient because to computer work, eye strain happens occasionally for a long time, eye dry eyes
Puckery problem is serious, using one day after, symptom has relaxed, and is taken a turn for the better after a course for the treatment of.
3. certain is permitted, man, 34 years old, white collar.Eye's fatigue more than two days, using ointment, using symptom after a day
Relax, taken a turn for the better after three days.
Technological means disclosed in the present invention program is not limited only to the technological means disclosed in above-mentioned implementation method, also includes
Constituted technical scheme is combined by above technical characteristic.It should be pointed out that for those skilled in the art
For, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications are also considered as
Protection scope of the present invention.
Claims (4)
1. a kind of eye ointment, it is characterised in that be made up of the raw material of following portions by weight:Pearl powder 8-14 parts, rhizoma atractylodis 5-9 parts, feather cockscomb
It is sub- 4-8 parts, peppermint 4-8 parts, purslane 6-10 parts, radix rehmanniae recen 6-12 parts, black soya bean 6-10 parts, lotus leaf 6-8 parts, feverfew 10-20
Part, Semen Leonuri 4-8 parts, rosemary 10-18 parts, vitamin A 0.02-0.08 parts, lutein 0.02-0.06 parts, eye pasting substrate
800-1600 parts, glycerine 2-6 parts, milk 4-8 parts, the eye pasting substrate is made up of albolene, atoleine and lanolin.
2. a kind of eye ointment as claimed in claim 1, it is characterised in that be made up of the raw material of following portions by weight:Pearl powder 11
Part, 7 parts of rhizoma atractylodis, 6 parts of the seed of feather cockscomb, 6 parts of peppermint, 8 parts of purslane, 9 parts of radix rehmanniae recen, 8 parts of black soya bean, 7 parts of lotus leaf, 15 parts of feverfew,
6 parts of Semen Leonuri, 14 parts of rosemary, 0.05 part of vitamin A, 0.03 part of lutein, eye pasting substrate 1200,4 parts of glycerine, 6 parts of milk,
The eye pasting substrate is made up of albolene, atoleine and lanolin.
3. a kind of eye ointment as claimed in claim 1 or 2, it is characterised in that the eye pasting substrate by following weight than raw material group
Into albolene:Atoleine:Lanolin=6:1:1.
4. a kind of preparation method for realizing the eye ointment described in claim 1, it is characterised in that comprise the following steps:First
Step, by rhizoma atractylodis, the seed of feather cockscomb, peppermint, purslane, radix rehmanniae recen, black soya bean, lotus leaf, feverfew, Semen Leonuri, rosemary is by weight
Weigh, clean, sterilize, dry, add 4-9 times of ethanol of raw material to invade bubble 4-10 hours, heating is decocted 1-2 hours, filtering obtains medicine
Slag 1 and filtrate 1;The dregs of a decoction 1 add 6-10 times of decocting to boil 0.5-2 hours, filter to obtain the dregs of a decoction 2 and filtrate 2, and filtrate 1 and filtrate are 2-in-1 simultaneously
Relative density is concentrated into for 1.01-1.03, concentrate is obtained;Second step, is matched somebody with somebody albolene, liquid paraffin, lanolin by proportioning
Matrix is made, 85-100 DEG C is heated to, when being cooled to 60-70 DEG C, above-mentioned concentrate and proportioning parts by weight pearl powder, dimension is added
Raw element A, lutein, glycerine, milk, mixing obtain eye ointment.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201611128195.3A CN106728321A (en) | 2016-12-09 | 2016-12-09 | A kind of eye ointment and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201611128195.3A CN106728321A (en) | 2016-12-09 | 2016-12-09 | A kind of eye ointment and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106728321A true CN106728321A (en) | 2017-05-31 |
Family
ID=58874829
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201611128195.3A Withdrawn CN106728321A (en) | 2016-12-09 | 2016-12-09 | A kind of eye ointment and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106728321A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107157923A (en) * | 2017-07-03 | 2017-09-15 | 武汉瑞福宁科技有限公司 | A kind of zoopery protection eye ointment and its application device |
CN115444803A (en) * | 2022-09-13 | 2022-12-09 | 武汉洁宜生物科技有限公司 | Antibacterial moisturizing medical eye protection patch and preparation method thereof |
CN116327846A (en) * | 2023-05-15 | 2023-06-27 | 普润德百目通(北京)科技有限公司 | Traditional Chinese medicine eye ointment for nourishing blood and improving eyesight and preparation method thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105833094A (en) * | 2016-05-24 | 2016-08-10 | 柳晖 | Traditional Chinese medicine composition for treating trachoma |
-
2016
- 2016-12-09 CN CN201611128195.3A patent/CN106728321A/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105833094A (en) * | 2016-05-24 | 2016-08-10 | 柳晖 | Traditional Chinese medicine composition for treating trachoma |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107157923A (en) * | 2017-07-03 | 2017-09-15 | 武汉瑞福宁科技有限公司 | A kind of zoopery protection eye ointment and its application device |
CN115444803A (en) * | 2022-09-13 | 2022-12-09 | 武汉洁宜生物科技有限公司 | Antibacterial moisturizing medical eye protection patch and preparation method thereof |
CN116327846A (en) * | 2023-05-15 | 2023-06-27 | 普润德百目通(北京)科技有限公司 | Traditional Chinese medicine eye ointment for nourishing blood and improving eyesight and preparation method thereof |
CN116327846B (en) * | 2023-05-15 | 2023-11-03 | 普润德百目通(北京)科技有限公司 | Traditional Chinese medicine eye ointment for nourishing blood and improving eyesight and preparation method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1060350C (en) | Chinese medicine for treatment of woman postpartum disease | |
CN106728321A (en) | A kind of eye ointment and preparation method thereof | |
CN1315457C (en) | Bath lotion for chilblain nursing and preparation method thereof | |
CN102793848B (en) | Traditional Chinese medicine powder for treating night blindness | |
CN104435831A (en) | Medicine for treating Meniere's disease and preparation method thereof | |
CN101249255B (en) | Proprietary Chinese medicine for curing children's cough and method of preparing the same | |
CN104491596A (en) | Traditional Chinese medicine composition for treating liver-kidney yin deficiency type stroke and application thereof | |
CN100579573C (en) | Chinese medicine composition orally taken for curing cervical vertebra osteoproliferation | |
CN103041215B (en) | Chinese medicament composition for treating hashimoto thyroiditis | |
CN101983666A (en) | Traditional Chinese medicine composition for treating rheumatism and preparation method thereof | |
CN101612380A (en) | A kind of Chinese medicine composition for the treatment of chilblain and preparation method thereof | |
CN101518579B (en) | Pressure stabilizing deoppilant and preparation process | |
CN100402077C (en) | Medicinal composition for treating hyperosteogency | |
CN104524479A (en) | Traditional Chinese medicine composition for treating premenstrual syndrome and preparation method of traditional Chinese medicine composition | |
CN110227142A (en) | A kind of liquid medicine and preparation method thereof | |
CN104173775A (en) | Traditional Chinese medicine composition for treating cervicogenic headache and preparation method of traditional Chinese medicine composition | |
CN101607007B (en) | Traditional Chinese medicine preparation for treating cerebral circulation insufficiency | |
CN102671115A (en) | Traditional Chinese medicine composition for treating headache and preparation method thereof | |
CN102028876B (en) | Liquid Chinese medicine for treating hyperosteogeny | |
CN101940744A (en) | Chinese herbal medicine for treating simple gastritis | |
CN101843810A (en) | Medicinal liquor for treating bi syndromes and preparation method thereof | |
CN105748679A (en) | Traditional Chinese medicine prescription for treating heat toxin and dysentery of pigs | |
CN105106692A (en) | Traditional Chinese medicinal composition for gallstone postoperative recovery and preparation method of traditional Chinese medicinal composition | |
CN102068615B (en) | Chinese medicinal liquid for treating sciatica | |
CN103800724A (en) | Traditional Chinese medicine for treating thyroiditis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170531 |
|
WW01 | Invention patent application withdrawn after publication |