CN106727981A - A kind of Chinese medicine composition for killing livestock and poultry vermin and its preparation method and application - Google Patents
A kind of Chinese medicine composition for killing livestock and poultry vermin and its preparation method and application Download PDFInfo
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Abstract
The present invention provides a kind of Chinese medicine composition for killing livestock and poultry vermin, and the Chinese medicine composition includes the Chinese medicine composition of volumes below part：23 parts of tree of heaven ailanthus bark water extract, bitter 13 parts of heart of a lotus seed Tween 80 mixed liquor；The bitter heart of a lotus seed Tween 80 mixed liquor is the mixed liquor of bitter heart of a lotus seed herb distillate and Tween 80, and in mixed liquor, the bitter heart of a lotus seed herb distillate is 5 with the volume ratio of Tween 80:1000‑1500.The present invention also provides its preparation method and application.Chinese medicine composition of the invention, using Chinese veterinarian's medicine compatibility principle, the nature and flavor and its effect of comprehensive medicine, the effect of not only having desinsection, can effectively kill livestock and poultry vermin, such as louse, acarid and tick, the anti-infective resistance against diseases of body can also be strengthened, the effect treated both principal and secondary aspect of disease is reached, while said preparation is without toxicity, side effect, noresidue, it is environmentally safe.
Description
Technical field
The invention belongs to veterinary drug technical field, and in particular to a kind of Chinese medicine composition of killing livestock and poultry vermin and its
Preparation method and application.
Background technology
Vermin parasitizes animal in vitro, belongs to non-chronicity parasite.The main vermin of livestock and poultry have tick,
Mite, lice, fly, flea, mosquito etc..There is very strong breeding and survival ability in the environment, and it is resistance to energetic.It is master that disease is mutually propagated
Want medium.
The amount reproduction of vermin, can make livestock and poultry cause anaemia, malnutrition, become thin, itching, exanthemv very
To Other diseases scabies secondary infection is caused, various diseases can be not only propagated between livestock and poultry, influence the development of livestock and poultry breeding industry, production
Power declines, and causes economic benefit to glide, and own health to public health and people brings significant threat.
Preventing and treating to epizoonosis, it is main include by hand and directly the killing of machinery, effective drug, biovaccine and
Method and the means such as pest-resistant livestock and poultry seed selection.Medical treatment is main based on chemical synthetic drug and antibiotic, but chemicals and
The long-term use of antibiotic easily makes parasite produce drug resistance, promotes the increase of the dosage during preventing and treating, does not only result in
Prevent and treat difficult problem to aggravate, and cause the pollution effect to environment, bad consequence is brought with health to public health.
Chinese herbal medicine has been reported and applies on veterinary clinic as the protective agents of vermin, its prevention effect
Confirmation and the affirmative of clinical practice are obtained.
The content of the invention
In order to solve problems of the prior art, the invention provides a kind of Chinese medicine for killing livestock and poultry vermin
Composition, has good killing effect to livestock and poultry vermin, and is not easy to develop immunity to drugs, and does not also result in environment dirty
Dye.
First purpose of the invention is to provide a kind of Chinese medicine composition for killing livestock and poultry vermin, the Chinese medicine group
Compound includes the Chinese medicine composition of volumes below part：2-3 parts of tree of heaven ailanthus bark water extract, the bitter heart of a lotus seed -1-3 parts of Tween-80 mixed liquor；It is described
The bitter heart of a lotus seed-Tween-80 mixed liquor is the mixed liquor of bitter heart of a lotus seed herb distillate and Tween-80, and in mixed liquor, the bitter heart of a lotus seed herb steams
Distillate is 5 with the volume ratio of Tween-80:1000-1500.
Preferably, the concentration of the tree of heaven ailanthus bark water extract is 1.5 grams of crude drug/mL.
Preferably, the bitter heart of a lotus seed herb distillate is distilled bitter heart of a lotus seed herb, 1g hardship heart of a lotus seed herb distillations
Obtain 1ml hardship heart of a lotus seed herb distillates.
Second object of the present invention is to provide the preparation method of above-mentioned Chinese medicine composition, and step is as follows：
（1）Tree of heaven ailanthus bark is boiled with decocting, tree of heaven ailanthus bark Aqueous extracts are collected；
（2）Bitter heart of a lotus seed herb is distilled, bitter heart of a lotus seed herb distillate is collected；
（3）In step（2）Bitter heart of a lotus seed herb distillate in add Tween-80, both volume ratios be 5:1000-1500, stirring
Uniformly, the bitter heart of a lotus seed-Tween-80 mixed liquor is obtained；
（4）By step（1）2-3 parts of the tree of heaven ailanthus bark Aqueous extracts of preparation and step（3）The bitter heart of a lotus seed of preparation -1-3 parts of Tween-80 mixed liquor
Well mixed, sterilization obtains Chinese medicine composition.
Preferably, step（1）In, described boil tree of heaven ailanthus bark decocting is 3 times of water of weight of addition in tree of heaven ailanthus bark, is decocted
Boil 2 times, decoct 30 minutes every time.
Third object of the present invention is to provide above-mentioned Chinese medicine composition and is preparing the medicine of killing livestock and poultry vermin
In application.
It is louse, acarid or tick as the vermin.
Fourth object of the present invention is to provide a kind of medicine, and the active ingredient of the medicine is that claim 1-3 is any
Described Chinese medicine composition.
Preferably, the medicine also includes medically acceptable auxiliary material.
Chinese medicine composition of the invention can be used directly as medicine, it is also possible to according to the general skill of this area
Art, in Chinese medicine composition, this adds medically acceptable auxiliary material to be used as medicine.In the case of above-mentioned, contain
Chinese medicine composition of the invention as active ingredient, therefore, good prevention effect is respectively provided with to livestock and poultry vermin.
Analysis on TCM prescriptions：
Tree of heaven ailanthus bark, it is bitter in taste, cold, puckery, return the channels and collaterals such as stomach, large intestine, the heart, liver, spleen, lung.With except heat, eliminating dampness, puckery intestines, hemostasis,
The special efficacy of desinsection.Cure mainly heat-clearing removing jaundice, let out dysentery, have blood in stool, hemorrhoid hemorrhage, ascariasis, sore tinea.Bitter heart of a lotus seed gas is pungent, bitter, it is slightly poisonous,
Cold nature, return lung, Liver Channel.Clearing heat and detoxicating, wind-dispelling heat-dissipating has positive effect to hypertension, hepatitis, dysentery, carbuncle furuncle treatment sore, its
Infusion is also highly effective to killing fly maggot.Tween-80 contributes to volatile oil to be uniformly dispersed as cosolvent.Tree of heaven ailanthus bark and hardship
The mutual compatibility of the heart of a lotus seed is used, and is complemented each other, and enhances the effects such as clearing heat and detoxicating, desinsection, hemostasis, convergence.
Chinese medicine composition of the invention, using Chinese veterinarian's medicine compatibility principle, the nature and flavor and its effect of comprehensive medicine not only have
There is desinsection, can effectively kill livestock and poultry vermin, such as louse, acarid and tick, moreover it is possible to strengthen body anti-infective
Resistance against diseases, reaches the effect treated both principal and secondary aspect of disease, while said preparation is without toxicity, side effect, noresidue, it is environmentally safe.
Specific embodiment
Following embodiment facilitates a better understanding of the present invention, but does not limit the present invention.Experiment in following embodiments
Method, unless otherwise specified, is conventional method.Test material used in following embodiments, unless otherwise specified, is city
Sell.
The formula of the Chinese medicine composition for killing livestock and poultry vermin of the invention is as follows：
Tree of heaven ailanthus bark water extract 2-3 parts by volume, the bitter heart of a lotus seed-Tween-80 mixed liquor 1-3 parts by volume；
The bitter heart of a lotus seed-Tween-80 the mixed liquor is the mixed liquor of bitter heart of a lotus seed herb distillate and Tween-80, in mixed liquor, the hardship
Heart of a lotus seed herb distillate is 5 with the volume ratio of Tween-80:1000-1500.
It is of the invention kill livestock and poultry vermin the preparation method of Chinese medicine composition be：
（1）A certain amount of Chinese medicine tree of heaven ailanthus bark is weighed, 3 times of weight originally water submerged is added, soaked overnight is decocted, and same method is decocted
Twice, every all over 30 minutes, decoction liquor 4-6 layers of filtered through gauze merges decoction liquor and concentrates decoction liquor to concentration when 150%（1.5 grams
Crude drug/mL）, place cool to room temperature, it is standby.
（2）The fresh bitter heart of a lotus seed herb of constant weight is weighed, is placed in distiller, distilled using vapour method, distilled
Liquid reaches certain volume（1 gram of drug weight correspondence 1mL distillate）When, distillate is collected, it is cool to room temperature.
（3）It is 5 according to volume ratio:The ratio of 1000-1500, in step（2）Add in collected bitter heart of a lotus seed herb distillate
Enter Tween-80, stir, emulsion dispersion is uniform, obtains the bitter heart of a lotus seed-Tween-80 mixed liquor.
（4）Take step（1）The Chinese medicine tree of heaven ailanthus bark liquid of preparation presses 2-3 parts by volume and step（3）The bitter heart of a lotus seed of preparation-tell
Warm -80 mixed liquor 1-3 parts by volume are mixed, and are stirred, and mixed liquor is uniformly dispersed.
（5）Brown glass reagent bottle is sub-packed in, is covered, carried out flowing steam and disinfect, 30-40 minutes, obtain Chinese medicine
Composition.
Smeared by cotton swab when using or be sprayed at body pars affecta skin surface.
Embodiment 1
The formula of the Chinese medicine composition for killing livestock and poultry vermin of the invention is as follows：
The parts by volume of tree of heaven ailanthus bark water extract 2.5, the bitter heart of a lotus seed-parts by volume of Tween-80 mixed liquor 2；
The bitter heart of a lotus seed-Tween-80 the mixed liquor is the mixed liquor of bitter heart of a lotus seed herb distillate and Tween-80, in mixed liquor, the hardship
Heart of a lotus seed herb distillate is 5 with the volume ratio of Tween-80:1000.
It is of the invention kill livestock and poultry vermin the preparation method of Chinese medicine composition be：
（1）A certain amount of Chinese medicine tree of heaven ailanthus bark is weighed, 3 times of weight originally water submerged is added, soaked overnight is decocted, and same method is decocted
Twice, every all over 30 minutes, 6 layers of filtered through gauze of decoction liquor merge decoction liquor and concentrate decoction liquor to concentration when 150%（1.5 grams of lifes
Medicine/mL）, place cool to room temperature, it is standby.
（2）The fresh bitter heart of a lotus seed herb of constant weight is weighed, is placed in distiller, distilled using vapour method, distilled
Liquid reaches certain volume（1 gram of drug weight correspondence 1mL distillate）When, distillate is collected, it is cool to room temperature.
（3）It is 5 according to volume ratio:1000 ratio, in step（2）Added in collected bitter heart of a lotus seed herb distillate and told
Temperature -80, stirring, emulsion dispersion is uniform, obtains the bitter heart of a lotus seed-Tween-80 mixed liquor.
（4）Take step（1）The Chinese medicine tree of heaven ailanthus bark liquid of preparation presses 2.5 parts by volume and step（3）The bitter heart of a lotus seed of preparation-tell
The warm parts by volume of -80 mixed liquor 2 is mixed, and is stirred, and mixed liquor is uniformly dispersed.
（5）Brown glass reagent bottle is sub-packed in, is covered, carried out flowing steam and disinfect, 40 minutes, obtain Chinese traditional medicine composition
Thing.
Smeared by cotton swab when using or be sprayed at body pars affecta skin surface.
Embodiment 2
The formula of the Chinese medicine composition for killing livestock and poultry vermin of the invention is as follows：
The parts by volume of tree of heaven ailanthus bark water extract 2, the bitter heart of a lotus seed-parts by volume of Tween-80 mixed liquor 3；
The bitter heart of a lotus seed-Tween-80 the mixed liquor is the mixed liquor of bitter heart of a lotus seed herb distillate and Tween-80, in mixed liquor, the hardship
Heart of a lotus seed herb distillate is 5 with the volume ratio of Tween-80:1500.
It is of the invention kill livestock and poultry vermin the preparation method of Chinese medicine composition be：
（1）A certain amount of Chinese medicine tree of heaven ailanthus bark is weighed, 3 times of weight originally water submerged is added, soaked overnight is decocted, and same method is decocted
Twice, every all over 30 minutes, 4 layers of filtered through gauze of decoction liquor merge decoction liquor and concentrate decoction liquor to concentration when 150%（1.5 grams of lifes
Medicine/mL）, place cool to room temperature, it is standby.
（2）The fresh bitter heart of a lotus seed herb of constant weight is weighed, is placed in distiller, distilled using vapour method, distilled
Liquid reaches certain volume（1 gram of drug weight correspondence 1mL distillate）When, distillate is collected, it is cool to room temperature.
（3）It is 5 according to volume ratio:1500 ratio, in step（2）Added in collected bitter heart of a lotus seed herb distillate and told
Temperature -80, stirring, emulsion dispersion is uniform, obtains the bitter heart of a lotus seed-Tween-80 mixed liquor.
（4）Take step（1）The Chinese medicine tree of heaven ailanthus bark liquid of preparation presses 2 parts by volume and step（3）The bitter heart of a lotus seed-the tween of preparation-
The parts by volume of 80 mixed liquor 3 is mixed, and is stirred, and mixed liquor is uniformly dispersed.
（5）Brown glass reagent bottle is sub-packed in, is covered, carried out flowing steam and disinfect, 30 minutes, obtain Chinese traditional medicine composition
Thing.
Smeared by cotton swab when using or be sprayed at body pars affecta skin surface.
Embodiment 3
The formula of the Chinese medicine composition for killing livestock and poultry vermin of the invention is as follows：
The parts by volume of tree of heaven ailanthus bark water extract 3, the bitter heart of a lotus seed-parts by volume of Tween-80 mixed liquor 1；
The bitter heart of a lotus seed-Tween-80 the mixed liquor is the mixed liquor of bitter heart of a lotus seed herb distillate and Tween-80, in mixed liquor, the hardship
Heart of a lotus seed herb distillate is 5 with the volume ratio of Tween-80:1200.
It is of the invention kill livestock and poultry vermin the preparation method of Chinese medicine composition be：
（1）A certain amount of Chinese medicine tree of heaven ailanthus bark is weighed, 3 times of weight originally water submerged is added, soaked overnight is decocted, and same method is decocted
Twice, every all over 30 minutes, 5 layers of filtered through gauze of decoction liquor merge decoction liquor and concentrate decoction liquor to concentration when 150%（1.5 grams of lifes
Medicine/mL）, place cool to room temperature, it is standby.
（2）The fresh bitter heart of a lotus seed herb of constant weight is weighed, is placed in distiller, distilled using vapour method, distilled
Liquid reaches certain volume（1 gram of drug weight correspondence 1mL distillate）When, distillate is collected, it is cool to room temperature.
（3）It is 5 according to volume ratio:1200 ratio, in step（2）Added in collected bitter heart of a lotus seed herb distillate and told
Temperature -80, stirring, emulsion dispersion is uniform, obtains the bitter heart of a lotus seed-Tween-80 mixed liquor.
（4）Take step（1）The Chinese medicine tree of heaven ailanthus bark liquid of preparation presses 3 parts by volume and step（3）The bitter heart of a lotus seed-the tween of preparation-
The parts by volume of 80 mixed liquor 1 is mixed, and is stirred, and mixed liquor is uniformly dispersed.
（5）Brown glass reagent bottle is sub-packed in, is covered, carried out flowing steam and disinfect, 30-40 minutes, obtain Chinese medicine
Composition.
Smeared by cotton swab when using or be sprayed at body pars affecta skin surface.
Embodiment 4
The formula of the Chinese medicine composition for killing livestock and poultry vermin of the invention is as follows：
The parts by volume of tree of heaven ailanthus bark water extract 2.5, the bitter heart of a lotus seed-parts by volume of Tween-80 mixed liquor 1；
The bitter heart of a lotus seed-Tween-80 the mixed liquor is the mixed liquor of bitter heart of a lotus seed herb distillate and Tween-80, in mixed liquor, the hardship
Heart of a lotus seed herb distillate is 5 with the volume ratio of Tween-80:1300.
It is of the invention kill livestock and poultry vermin the preparation method of Chinese medicine composition be：
（1）A certain amount of Chinese medicine tree of heaven ailanthus bark is weighed, 3 times of weight originally water submerged is added, soaked overnight is decocted, and same method is decocted
Twice, every all over 30 minutes, 6 layers of filtered through gauze of decoction liquor merge decoction liquor and concentrate decoction liquor to concentration when 150%（1.5 grams of lifes
Medicine/mL）, place cool to room temperature, it is standby.
（2）The fresh bitter heart of a lotus seed herb of constant weight is weighed, is placed in distiller, distilled using vapour method, distilled
Liquid reaches certain volume（1 gram of drug weight correspondence 1mL distillate）When, distillate is collected, it is cool to room temperature.
（3）It is 5 according to volume ratio:1300 ratio, in step（2）Added in collected bitter heart of a lotus seed herb distillate and told
Temperature -80, stirring, emulsion dispersion is uniform, obtains the bitter heart of a lotus seed-Tween-80 mixed liquor.
（4）Take step（1）The Chinese medicine tree of heaven ailanthus bark liquid of preparation presses 2.5 parts by volume and step（3）The bitter heart of a lotus seed of preparation-tell
The warm parts by volume of -80 mixed liquor 1 is mixed, and is stirred, and mixed liquor is uniformly dispersed.
（5）Brown glass reagent bottle is sub-packed in, is covered, carried out flowing steam and disinfect, 35 minutes, obtain Chinese traditional medicine composition
Thing.
Smeared by cotton swab when using or be sprayed at body pars affecta skin surface.
Embodiment 5
The formula of the Chinese medicine composition for killing livestock and poultry vermin of the invention is as follows：
The parts by volume of tree of heaven ailanthus bark water extract 3, the bitter heart of a lotus seed-parts by volume of Tween-80 mixed liquor 3；
The bitter heart of a lotus seed-Tween-80 the mixed liquor is the mixed liquor of bitter heart of a lotus seed herb distillate and Tween-80, in mixed liquor, the hardship
Heart of a lotus seed herb distillate is 5 with the volume ratio of Tween-80:1100.
It is of the invention kill livestock and poultry vermin the preparation method of Chinese medicine composition be：
（1）A certain amount of Chinese medicine tree of heaven ailanthus bark is weighed, 3 times of weight originally water submerged is added, soaked overnight is decocted, and same method is decocted
Twice, every all over 30 minutes, 4 layers of filtered through gauze of decoction liquor merge decoction liquor and concentrate decoction liquor to concentration when 150%（1.5 grams of lifes
Medicine/mL）, place cool to room temperature, it is standby.
（2）The fresh bitter heart of a lotus seed herb of constant weight is weighed, is placed in distiller, distilled using vapour method, distilled
Liquid reaches certain volume（1 gram of drug weight correspondence 1mL distillate）When, distillate is collected, it is cool to room temperature.
（3）It is 5 according to volume ratio:1100 ratio, in step（2）Added in collected bitter heart of a lotus seed herb distillate and told
Temperature -80, stirring, emulsion dispersion is uniform, obtains the bitter heart of a lotus seed-Tween-80 mixed liquor.
（4）Take step（1）The Chinese medicine tree of heaven ailanthus bark liquid of preparation presses 3 parts by volume and step（3）The bitter heart of a lotus seed-the tween of preparation-
The parts by volume of 80 mixed liquor 3 is mixed, and is stirred, and mixed liquor is uniformly dispersed.
（5）Brown glass reagent bottle is sub-packed in, is covered, carried out flowing steam and disinfect, 30-40 minutes, obtain Chinese medicine
Composition.
Smeared by cotton swab when using or be sprayed at body pars affecta skin surface.
Embodiment 6
The pharmacological evaluation of Chinese medicine composition of the invention：
1st, experiment in vitro：Three kinds of various concentrations of the Chinese medicine composition prepared with embodiments of the invention 1 are tested：I.e. 4 times
Dilution, 2 times of dilutions and original liquid.
（1）Crawl pig body surface louse, is put in four plates with cover, each plate 20, after placing 1 day, is added dropwise respectively
Physiological saline, 4 times of dilute liquid medicines, 2 times of dilute liquid medicines and original liquid, added liquid just soak whole bottom surfaces, should not mistake
It is many.Plate lid is covered, 28-30 DEG C is positioned over, cultivated in the insulating box of humidity 50%, observed with magnifying glass.
As a result：The louse of physiological saline is added dropwise 72 hours, there are 18 also it is observed that foot has obvious light activity；
4 times of dilute liquid medicine plates of observation, at 30 hours, 90% dead was 36 hours, all dead；2 times of dilute liquid medicine plates, 20 is small
When, 80% dead, 30 hours, 100% is dead；Observation original liquid plate, 8 hours 50% deads, 12 hours, 100% dead.
（2）The tick 25 for parasitizing ox-hide skin is taken, according to（1）Middle group technology, is tested every other day by every group 5, added
Amount of liquid is advisable with not flooding polypide.Insulating box culture under similarity condition, and observed.
As a result：The polypide that physiological saline is added dropwise does not find death in 72 hours, all there is mobility；4 times of dilute liquid medicines are put down
Polypide in ware, 36 hours, 2 death, 60 hours are all dead；Polypide in 2 times of dilute liquid medicine plates, 48 hours all dead
Die；The polypide of original liquid is added dropwise, 12 hours, mobility was extremely weak, observation in 24 hours is all dead.
（3）The skin with acarid of itch mite rabbit is suffered from gripping, separates polypide, every group 20, is pressed（1）Method cultivated,
And observe.
As a result：The acarid of physiological saline is added dropwise, 72 hours, there are 17 still it is observed that foot has slight activity；Observation 4
Acarid in times dilute liquid medicine plate, at 30 hours, 80% dead was 40 hours, all dead；Mite in 2 times of dilute liquid medicine plates
Worm, 24 hours, 80% dead, 36 hours, 100% is dead；Acarid in observation original liquid plate, 12 hours 60% deads, 24 is small
When, 100% dead.
（1）-（3）All experiments in, while separately setting Tween-80 group, dilution factor is 1:2000, all results with life
Reason salt solution group is similar.
The dermal toxicity test of Chinese medicine composition of the invention：
Choose adult healthy rabbits（About 2kg）, cut off back backbone diamond wool, area about 150cm2.It is divided into 5 groups, applies respectively
Wipe physiological saline, 4 times of dilutions, 2 times of dilutions, original liquids and 1:2000 Tween-80, continuously embrocates 7 days.As a result：Experiment
There is not any exception in the skin of group rabbit, and the rabbit skin embrocated with physiology salt salt solution compares indifference.After being discontinued 3 days, then use
State liquid carries out an eye test respectively, 12 hours, 24 hours, 48 hours observation eye mucosa change, as a result：All experimental rabbits
, there is not rubescent and bleeding and other anomalies such as shed tears in eye mucosa.
The clinical test of Chinese medicine composition of the invention：
The 2 times of dilute liquid medicines of Chinese medicine composition and original liquid prepared using embodiment of the present invention 1-5 carry out Preliminay clinical trials, with
The chicken of parasitic louse, pig, the ox for suffering from acariasis sheep and infection tick is experimental subjects.
Result shows, chicken, pig, the sheep embrocated using original liquid, and after 3 days, parasite is all dead, dead worm for continuous use
Body has disengaged from skin；2 times of liquids of dilution, when medication was to 5 days, polypide swells and dead.
For the tick worm for parasitizing ox, original liquid medication is shrivelled to tick worm appearance at 3 days, when continuing medication to 5 days, polypide
Death departs from skin.When 2 times of dilute liquid medicines were to 3 days, there is swelling in some tick worms, and some appearance are more apparent shrivelled, during to 7 days,
Substantially it is dead, depart from skin.
Overall efficiency is up to 100%, cure rate more than 98% after medication.The relatively dilute liquid liquid effect of original liquid is obvious.
Finally it should be noted that：The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention,
Although being described in detail to the present invention with reference to the foregoing embodiments, for a person skilled in the art, it still may be used
Modified with to the technical scheme described in foregoing embodiments, or equivalent is carried out to which part technical characteristic.
All any modification, equivalent substitution and improvements within the spirit and principles in the present invention, made etc., should be included in of the invention
Within protection domain.
Claims (9)
1. it is a kind of kill livestock and poultry vermin Chinese medicine composition, it is characterised in that：The Chinese medicine composition is included with lower body
The Chinese medicine composition of product part：2-3 parts of tree of heaven ailanthus bark water extract, the bitter heart of a lotus seed -1-3 parts of Tween-80 mixed liquor；The bitter heart of a lotus seed-the Tween-80 is mixed
Close the mixed liquor that liquid is bitter heart of a lotus seed herb distillate and Tween-80, in mixed liquor, the bitter heart of a lotus seed herb distillate and Tween-80
Volume ratio be 5:1000-1500.
2. Chinese medicine composition according to claim 1, it is characterised in that：The concentration of the tree of heaven ailanthus bark water extract is 1.5 grams
Crude drug/mL.
3. Chinese medicine composition according to claim 1, it is characterised in that：The bitter heart of a lotus seed herb distillate is by bitter heart of a lotus seed herb
Carry out distilling what is obtained, 1g hardship heart of a lotus seed herb distillations obtain 1ml hardship heart of a lotus seed herb distillates.
4. the preparation method of any described Chinese medicine compositions of claim 1-3, it is characterised in that：Step is as follows：
（1）Tree of heaven ailanthus bark is boiled with decocting, tree of heaven ailanthus bark Aqueous extracts are collected；
（2）Bitter heart of a lotus seed herb is distilled, bitter heart of a lotus seed herb distillate is collected；
（3）In step（2）Bitter heart of a lotus seed herb distillate in add Tween-80, both volume ratios be 5:1000-1500, stirring
Uniformly, the bitter heart of a lotus seed-Tween-80 mixed liquor is obtained；
（4）By step（1）2-3 parts of the tree of heaven ailanthus bark Aqueous extracts of preparation and step（3）The bitter heart of a lotus seed of preparation -1-3 parts of Tween-80 mixed liquor
Well mixed, sterilization obtains Chinese medicine composition.
5. preparation method according to claim 4, it is characterised in that：Step（1）In, described boil tree of heaven ailanthus bark decocting is
3 times of water of weight are added in tree of heaven ailanthus bark, is decocted 2 times, decocted 30 minutes every time.
6. application of any described Chinese medicine compositions of claim 1-3 in the medicine for killing livestock and poultry vermin is prepared.
7. application according to claim 6, it is characterised in that：The livestock and poultry vermin is louse, acarid or tick.
8. a kind of medicine, it is characterised in that：The active ingredient of the medicine is any described Chinese traditional medicine compositions of claim 1-3
Thing.
9. medicine according to claim 8, it is characterised in that：The medicine also includes medically acceptable auxiliary material.
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| CN104705339A (en) * | 2015-04-09 | 2015-06-17 | 陈会良 | Insecticide for preventing and treating ectoparasites of livestock and poultry |
| CN105687188A (en) * | 2014-11-25 | 2016-06-22 | 洛阳惠中兽药有限公司 | Parasite prevention and/or treatment pharmaceutical composition and preparation method and application thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105687188A (en) * | 2014-11-25 | 2016-06-22 | 洛阳惠中兽药有限公司 | Parasite prevention and/or treatment pharmaceutical composition and preparation method and application thereof |
| CN104705339A (en) * | 2015-04-09 | 2015-06-17 | 陈会良 | Insecticide for preventing and treating ectoparasites of livestock and poultry |
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| Title |
|---|
| 沈阳药学院药剂教研组: "《常用药物制剂》", 30 November 1975, 辽宁人民出版社 * |
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