CN106727154A - Anti-acne gel and its preparation technology - Google Patents

Anti-acne gel and its preparation technology Download PDF

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Publication number
CN106727154A
CN106727154A CN201710019779.5A CN201710019779A CN106727154A CN 106727154 A CN106727154 A CN 106727154A CN 201710019779 A CN201710019779 A CN 201710019779A CN 106727154 A CN106727154 A CN 106727154A
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China
Prior art keywords
water
extract
acne
thickener
solvent
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CN201710019779.5A
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Inventor
吴志刚
张文泽
贺沛如
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HANGZHOU FACECARE COSMETICS Co Ltd
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HANGZHOU FACECARE COSMETICS Co Ltd
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Priority to CN201710019779.5A priority Critical patent/CN106727154A/en
Publication of CN106727154A publication Critical patent/CN106727154A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8158Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants

Abstract

The invention discloses a kind of anti-acne gel and its preparation technology, wherein, anti-acne gel includes the component of following weight/mass percentage composition:First solvent 15 50%;Salicylic acid 0.3 3%;Skin conditioning agent 0.7 14%;Thickener 0.8 3%;Camphor 0.05 1%;Melaleuca alternifolia leaf oil 0.05 0.5%;Balance of water and preservative;First solvent includes 5% water and 95% ethanol;Skin conditioning agent includes one or more in hamamelis extract mixtures, Aloe Barbadensis Miller extract mixtures, tea extract mixture;Thickener includes 10 20% polyacrylamides, 70 88% water, the isoparaffins of 1 5% C13 14,1 5% laureth 7.The present invention has gentle anti-acne, moisturizing, the effect of anti-acne.

Description

Anti-acne gel and its preparation technology
Technical field
The present invention relates to cosmetic technical field, more specifically, it relates to a kind of anti-acne gel and its preparation technology.
Background technology
As industry and rapid development of economy, air pollution are further exacerbated by, the work of people and rhythm of life get over Come faster, and bad work and rest custom and incorrect skin nursing under high pressure life, easily cause dry, coarse, skin The disorderly synthtic price index of the skins such as color is obscure, pore is thick, small pox, and in recent years, these phenomenons are in rising trend.Acne Acne is a kind of chronic inflammatory skin of pilosebaceous follicle, is mainly in all kinds of skins such as acne, papule, warts, the tubercle of face Skin is damaged.The factors such as the generation of acne and hypersteatosis, pilosebaceous duct are blocked, bacterium infection and inflammatory reaction are close Cut is closed.It is slow that it repairs course of disease, and easily repeatedly, it is attractive in appearance to have a strong impact on beauty, causes larger to people's mental health and quality of life Influence.
The product for resolving poxes that people typically use at present is being coated on the small pox surface of face, is rapid recovery skin surface acne Acne phenomenon, generally adds hormonal substance, although can reach the effect of potent anti-acne in the product for resolving poxes of prior art, but for a long time Use, easily cause easy dependence of the acne crowd long to such product, and reduce the antiallergy ability of skin, skin is in inferior health State;Meanwhile, in use, such product for resolving poxes is contacted with small pox, reaches the effect for dispelling acne, but due to wherein containing There is hormone, for easily causing hormone face after the skin of acne not long, injure skin, small pox is grown simultaneously so as to be difficult to prevention normal skin Skin is kept to be in normal condition.Therefore, it is a kind of to be applicable to acne-removing and again the product for resolving poxes of skin anti-acne and have Commercial value higher.
The content of the invention
In view of the shortcomings of the prior art, the purpose of the present invention one is to provide a kind of anti-acne gel, which solves and contains The product for resolving poxes for having hormonal substance easily reduces the antiallergy ability of skin, and is difficult to be applied to the problem of normal skin, has Gentle anti-acne, moisturizing, anti-acne advantage.
To achieve the above object one, the invention provides following technical scheme:
A kind of anti-acne gel, including following weight/mass percentage composition component:
First solvent 15-50%;
Salicylic acid 0.3-3%;
Skin conditioning agent 0.7-14%;
Thickener 0.8-3%;
Camphor 0.05-1%;
Alternate leaf white spirit layer leaf oil 0.05-0.5%;
Balance of water and preservative;
First solvent includes the water of 5wt% and the ethanol of 95wt%;The skin conditioning agent is extracted including hamamelis One or more in thing mixture, Aloe Barbadensis Miller extract mixtures, tea extract mixture;The thickener bag Include 10-20wt% polyacrylamides, 70-88wt% water, 1-5wt%C13-14 isoparaffins, 1-5wt% laureths -7.
Using above-mentioned technical proposal, the first solvent is the mixture of water and ethanol, contributes to the dissolving of the compositions such as salicylic acid, Uniform Aqueous dispersions system is formed, so that the anti-acne gel in the application has and softening and peeling off cutin, dissolve blackhead powder The effect of thorn, helps lend some impetus to the metabolism of skin, reduces clogging of pores phenomenon, and play the effect of desalination acne print.
The thickener that polyacrylamide, water, C13-14 isoparaffins, laureth -7 are mixed to form, with translucent Outward appearance, and in its anti-acne gel in this application have good stability, make each component in the application in liquid ring Good dispersion, emulsification and thickening effect are can reach in border, is in the anti-acne gel to be formed slightly thick, help to be detained In skin surface, and reduce the possibility of quick drippage.After anti-acne gel is applied to normal skin or rises at acne, guarantor can be formed Cuticula, pins active ingredient, and gentle and moisturizing longer, anti-inflammatory simultaneously stimulate circulation, and reduce the possibility that small pox occurs, or The time needed for dispelling small pox is reduced, meanwhile, can also effectively stop infringement of the polluter in the external world to skin, reduce pore and block up The probability of plug.
Tested through using effect and found, the first solvent, salicylic acid, skin conditioning agent, thickener, Melaleuca alternifolia leaf oil After compounding, make the anti-acne gel in the application that there is preferably gentle, replenishing water and preserving moisture, skin of releiving, reduce allergic phenomena, and protect Water and oil balance is held, the probability that small pox occurs is reduced, and also anti-inflammatory and healing can be carried out to small pox;Thick hair can also be refined Hole, softens and removes blackhead, reduces the possibility of clogging of pores;Additionally, the function of blood circulation and skin regeneration is may additionally facilitate, it is light Change acne print.
More preferably:Component including following weight/mass percentage composition:
First solvent 15-50%;
Salicylic acid 0.3-3%;
Skin conditioning agent 0.7-14%;
Thickener 0.8-3%;
Camphor 0.05-1%;
Alternate leaf white spirit layer leaf oil 0.05-0.5%;
Balance of water and preservative;
First solvent includes the water of 5wt% and the ethanol of 95wt%;The skin conditioning agent chooses 0.5-8% North Americas gold thread Prunus mume extract mixture, 0.1-3% Aloe Barbadensis Millers extract mixtures, 0.1-3% tea extract mixtures;The increasing Thick dose includes that 10-20wt% polyacrylamides, 70-88wt% water, 1-5wt%C13-14 isoparaffins, 1-5wt% laruyl alcohols gather Ether -7.
Using above-mentioned technical proposal, skin conditioning agent choose the composition than hamamelis extract mixtures, Ku La Rope Folium Aloe extract mixture is constituted, and makes the anti-acne and anti-acne effect of anti-acne gel more preferably, and is coated during to skin surface, clearly Thoroughly, greasy, effective moisturizing and skin of releiving are not sticked.
More preferably:Component including following weight/mass percentage composition:
First solvent 15-50%;
Salicylic acid 0.3-3%;
Hamamelis extract mixtures 0.5-8%;
Aloe Barbadensis Miller extract mixtures 0.1-3%;
Tea extract mixture 0.1-3%;
Thickener 0.8-3%;
Camphor 0.05-1%;
Melaleuca alternifolia leaf oil 0.05-0.5%;
Balance of water and preservative;
First solvent includes the water of 5wt% and the ethanol of 95wt%;The hamamelis extract mixtures include The water of 77.5-79.45wt%, 20wt% butanediols, 0.05-2.0wt% hamamelis extract, 0.5wt% Phenoxyethanols; The Aloe Barbadensis Miller extract mixtures include 79.5-84.5wt% water, 10wt% butanediols, 5-10wt% Curacao reeds Luxuriant growth leaf extract, 0.5wt% Phenoxyethanols;The tea extract mixture includes 69.4wt% water, 29.6-30wt% fourths two Alcohol, 0.1-0.5wt% tea extracts, 0.5wt% Phenoxyethanols;The thickener include 10-20wt% polyacrylamides, 70-88wt% water, 1-5wt%C13-14 isoparaffins, 1-5wt% laureths -7.
Using above-mentioned technical proposal, hamamelis extract, aloe barbadensis Miller leaf extract, tea extract are used Carbon dioxide supercritical extraction is obtained, and organic solvent is provided without in extraction process, retains more complete natural herb elite, Safe antiallergy.
Wherein, various tannin matter are contained in hamamelis extract, sebum secretion, and the work with antibacterial is can adjust With moisture-keeping function of the reinforcement to skin;Meanwhile, also with skin blood circulation is promoted, effect of skin regeneration is helped, contribute to The elimination of small pox simultaneously desalinates acne print.Aloe barbadensis Miller leaf extract has the effect of excellent sterilization, anti-inflammatory, replenishing water and preserving moisture, can Repair the skin being damaged after anti-acne.It can also effectively stablize melanin activity enzyme, promote established melanin fast decoupled simultaneously It is metabolized, and tissue melanin is formed once again.Tea extract has preferable antiallergy and antiinflammation, also with anti-oxidant Effect, removes the free radical that skin is formed, so as to suppress activity and the lipid peroxidation of LOX so that skin is young Change.Through using effect test find, hamamelis extract, aloe barbadensis Miller leaf extract, tea extract butanediol, Under the interaction of Phenoxyethanol, three kinds of compositions can be made to play synergy, after anti-acne gel is coated on skin surface, can It is quick to form diaphragm, moisturizing and moisturizing are carried out to skin;For sensitive, also with preferable antiallergic effect;It is right Skin at acne, with excellent sterilization, anti-inflammatory, analgesic effect, so that the small pox for being formed relatively rapid is controlled More, and to acne print also there is more preferable fading effect.
More preferably:Component including following weight/mass percentage composition:
First solvent 30-50%;
Salicylic acid 1.5-3%;
Hamamelis extract mixtures 5-8%;
Aloe Barbadensis Miller extract mixtures 0.8-3%;
Tea extract mixture 2.2-3%;
Thickener 2-3%;
Camphor 0.5-1%;
Melaleuca alternifolia leaf oil 0.3-0.5%;
Balance of water and preservative;
First solvent includes the water of 5wt% and the ethanol of 95wt%;The hamamelis extract mixtures include The water of 77.5-79.45wt%, 20wt% butanediols, 0.05-2.0wt% hamamelis extract, 0.5wt% Phenoxyethanols; The Aloe Barbadensis Miller extract mixtures include 79.5-84.5wt% water, 10wt% butanediols, 5-10wt% Curacao reeds Luxuriant growth leaf extract, 0.5wt% Phenoxyethanols;The tea extract mixture includes 69.4wt% water, 29.6-30wt% fourths two Alcohol, 0.1-0.5wt% tea extracts, 0.5wt% Phenoxyethanols;The thickener include 10-20wt% polyacrylamides, 70-88wt% water, 1-5wt%C13-14 isoparaffins, 1-5wt% laureths -7.
Using above-mentioned technical proposal, tested through using effect and find have using product obtained in the component in above range There are more preferable moisturizing, moisturizing, anti-acne, the effect of going acne print.
The purpose of the present invention two is to provide a kind of preparation technology of anti-acne gel.
To achieve the above object two, the invention provides following technical scheme:
A kind of preparation technology of anti-acne gel, comprises the following steps:
Step one, 5wt% water, 95wt% ethanol are sufficiently mixed, and form the first solvent;
Step 2, by 77.5-79.45wt% water, 20wt% butanediols, 0.05-2.0wt% hamamelis extract, 0.5wt% Phenoxyethanols are sufficiently mixed, and form hamamelis extract mixtures;
Step 3, by 79.5-84.5wt% water, 10wt% butanediols, 5-10wt% aloe barbadensis Millers leaf extract, 0.5wt% Phenoxyethanol is sufficiently mixed, and forms Aloe Barbadensis Miller extract mixtures;
Step 4, by 69.4wt% water, 29.6-30wt% butanediols, 0.1-0.5wt% tea extracts, 0.5wt% benzene oxygen second Alcohol is sufficiently mixed, and forms tea extract mixture;
Step 5, by 10-20wt% polyacrylamides, 70-88wt% water, 1-5wt%C13-14 isoparaffins, the 1-5wt% months Laureth -7 is sufficiently mixed, and forms thickener;
Step 6, first solvent of the 15-50% obtained in step one is sufficiently mixed with the salicylic acid of 0.3-3%, forms water Poplar acid solution;
Step 7, heats water to 78-80 DEG C, and 40-45 DEG C is cooled to after insulation half an hour, then at wherein adding by step 5 The salicylic acid solution of acquisition, is sufficiently mixed, and forms bigcatkin willow acid hydrate;
Step 8, in the hamamelis extract mixtures that will be prepared in 0.5-8% step 2,0.1-3% step 3 The tea extract mixture obtained in Aloe Barbadensis Miller extract mixtures, the 0.1-3% step 4 of acquisition is added to step In the rapid seven bigcatkin willow acid hydrates for obtaining, dispersed with stirring is uniform;0.05-0.5% alternate leaves white spirit layer leaf oil, 0.05- are added afterwards 1% camphor, is sufficiently mixed;The thickener obtained in 0.8-3% step 5 is added, is sufficiently stirred for, be eventually adding preservative, stirred Mix and be uniformly dispersed, obtain finished product, detection, discharging.
Tested through even results and found, using above-mentioned technical proposal, the hamamelis extract in the product of acquisition is mixed Compound, Aloe Barbadensis Miller extract mixtures, tea extract mixture, thickener, salicylic acid mix more abundant.
More preferably:The preservative includes 0.3-1wt% Sodium Benzoates.
Using above-mentioned technical proposal, preservative within the range can be with respect to the anti-acne gel extended after opening and using Effective life.
In sum, the invention has the advantages that:
1st, using effect experiment finds that the first solvent, salicylic acid, skin conditioning agent, thickener, alternate leaf white spirit layer leaf oil are compounded Afterwards, making the anti-acne gel in the application has preferably gentle, replenishing water and preserving moisture, skin of releiving, and reduces allergic phenomena, and keep water Oil balance, reduces the probability that small pox occurs, and also can carry out anti-inflammatory and healing to small pox;Thick pore can be also refined, it is soft Change and remove blackhead, reduce the possibility of clogging of pores;Additionally, may additionally facilitate the function of blood circulation and skin regeneration, desalinate acne Print;
2nd, using effect experiment finds that hamamelis extract, aloe barbadensis Miller leaf extract, tea extract are in fourth two Under alcohol, the interaction of Phenoxyethanol, three kinds of compositions can be made to play synergy, when anti-acne gel is coated on skin surface Afterwards, diaphragm can be quickly formed, moisturizing and moisturizing is carried out to skin;For sensitive, also imitated with preferable antiallergy Really;For playing the skin at acne, with excellent sterilization, anti-inflammatory, analgesic effect, so that the small pox for being formed is relatively rapid It is cured, and also has more preferable fading effect to acne print;
3rd, using effect experiment finds have more preferable moisturizing, moisturizing using product obtained in the component in above range, resist Acne, the effect for going acne print;
4th, even results experiment finds, using above-mentioned technical proposal, hamamelis extract mixtures in the product of acquisition, Aloe Barbadensis Miller extract mixtures, tea extract mixture, thickener, salicylic acid mix more abundant.
Specific embodiment
With reference to embodiment, the present invention will be described in detail.
Embodiment 1:Anti-acne gel, each component and its corresponding weight/mass percentage composition are as shown in table 1, and as follows Prepare:
Step one, water, ethanol are sufficiently mixed, and form the first solvent;
Step 2, water, butanediol, hamamelis extract, Phenoxyethanol are sufficiently mixed, and form hamamelis extract Mixture;
Step 3, water, butanediol, aloe barbadensis Miller leaf extract, Phenoxyethanol are sufficiently mixed, and are formed Aloe Barbadensis Miller and are carried Take thing mixture;
Step 4, water, butanediol, tea extract, Phenoxyethanol are sufficiently mixed, and form tea extract mixture;
Step 5,1 polyacrylamide, water, C13-14 isoparaffins, laureth -7 are sufficiently mixed, and form thickener;
Step 6, the first solvent obtained in step one is sufficiently mixed with salicylic acid, forms salicylic acid solution;
Step 7, heats water to 78 DEG C, 45 DEG C are cooled to after insulation half an hour, then at wherein adding by being obtained in step 5 Salicylic acid solution, is sufficiently mixed, and forms bigcatkin willow acid hydrate;
Step 8, the Curacao reed obtained in the hamamelis extract mixtures, the step 3 that will be prepared in step 2 The tea extract mixture obtained in luxuriant growth leaf extract mixture, step 4 adds the bigcatkin willow acid hydrate obtained to step 7 In, dispersed with stirring is uniform;Melaleuca alternifolia leaf oil, camphor are added afterwards, are sufficiently mixed;Add the thickening obtained in step 5 Agent, is sufficiently stirred for, and is eventually adding preservative, and dispersed with stirring is uniform, obtains finished product.
Embodiment 2:Anti-acne gel, the difference with embodiment 1 is, each component and its respective quality percentage composition such as table 1 It is shown.
Embodiment 3:Anti-acne gel, the difference with embodiment 1 is, each component and its respective quality percentage composition such as table 1 It is shown, and heat water to 80 DEG C in step 7, it is cooled to 40 DEG C after insulation half an hour.
Each component and respective quality percentage composition in the embodiment 1-3 of table 1
Note:If non-specifically is indicated in the application, the equal representation quality percentage composition of ratio.
Embodiment 4:Anti-acne gel, the difference with embodiment 3 is, all hamamelis extracts of skin conditioning agent Mixture.
Embodiment 5:Anti-acne gel, the difference with embodiment 3 is that all Aloe Barbadensis Millers of skin conditioning agent are extracted Thing mixture.
Embodiment 6:Anti-acne gel, the difference with embodiment 3 is that all tea extracts of skin conditioning agent mix Thing.
Embodiment 7:Anti-acne gel, the difference with embodiment 3 is that skin conditioning agent mixes for hamamelis extract The mix products of thing and Aloe Barbadensis Miller extract mixtures.
Embodiment 8:Anti-acne gel, the difference with embodiment 3 is that skin conditioning agent mixes for hamamelis extract The mix products of thing and tea extract mixture.
Embodiment 9:Anti-acne gel, the difference with embodiment 3 is that skin conditioning agent is tea extract mixture and storehouse The mix products of drag-line Folium Aloe extract mixture.
Embodiment 10:Anti-acne gel, the difference with embodiment 3 is that 79 DEG C are heated water in step 7, and insulation half is small When after be cooled to 43 DEG C.
Comparative example 1:Anti-acne gel, the difference with embodiment 3 is that the content of each component is distinguished by weight percentage For:Acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.3~0.8%, glycerine 2.0~5.0%, 1,3- fourths Glycol 2.0~5.0%, hamamelis extract 2.0~5.0%, pearl hydrolysate liposome 3.0~8.0%, phytosterol 1.0~5.0%, decoyl glycine 0.2~1.0%, allantoin 0.1~0.2%, dipotassium glycyrrhizinate 0.1~0.4%, double imidazoles Ureine 0.1~0.5%, methyl hydroxybenzoate 0.1~0.2%, triethanolamine 0.5~1.0%, disodium ethylene diamine tetraacetate 0.05~ 0.15%, balance of water.The anti-acne gel is made by the steps acquisition:
1st, add after acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymers are soaked 0.5~1.5 hour with deionized water Glycerine, 1,3-BDO, hamamelis extract, allantoin, methyl hydroxybenzoate, disodium ethylene diamine tetraacetate mixing input emulsification pot are stirred Mix and be heated to 80~85 DEG C;Keep vacuum and constantly deaerate, until transparent without steam bubble;
2nd, 80~85 DEG C when add triethanolamine stir;
3rd, being cooled to 40~50 DEG C adds pearl hydrolysate liposome, phytosterol, decoyl glycine, double imidazolidinyl urea to stir Mix uniform discharge and obtain finished product.
Comparative example 2:Anti-acne gel, the difference with embodiment 3 is, all water in the first solvent.
Comparative example 3:Anti-acne gel, the difference with embodiment 3 is, all ethanol in the first solvent.
Comparative example 4:Anti-acne gel, the difference with embodiment 3 is, wherein without hamamelis extract, Curacao Folium Aloe extract, tea extract.
Comparative example 5:Anti-acne gel, the difference with embodiment 3 is, wherein without aloe barbadensis Miller leaf extract, tealeaves Extract.
Comparative example 6:Anti-acne gel, the difference with embodiment 3 is, wherein without tea extract.
Comparative example 7:Anti-acne gel, the difference with embodiment 3 is, wherein without polyacrylamide, the different alkanes of C13-14 Hydrocarbon, laureth -7.
Comparative example 8:Anti-acne gel, the difference with embodiment 3 is, wherein gathering without C13-14 isoparaffins, laruyl alcohol Ether -7.
Comparative example 9:Anti-acne gel, the difference with embodiment 3 is, wherein laureth -7.
Comparative example 10:Anti-acne gel, the difference with embodiment 3 is, wherein without salicylic acid.
Comparative example 11:Anti-acne gel, the difference with embodiment 3 is, wherein without alternate leaf white spirit layer leaf oil.
Comparative example 12:Anti-acne gel, the difference with embodiment 3 is to be prepared using following steps:
66.168% water, 28.5% ethanol, 1.661% butanediol, 0.041% Phenoxyethanol, 0.003% hamamelis are carried Take thing, 1.5% salicylic acid, 0.45% polyacrylamide, 0.09%C13-14 isoparaffins, 0.06 laureth -7,0.5% Camphor, 0.7% Sodium Benzoate, 0.3% Melaleuca alternifolia leaf oil, 0.005% aloe barbadensis Miller leaf extract, 0.022% tea Leaf extract is together well mixed, and is obtained.
Test using effect experiment
Test specimen:Using the mascara obtained in embodiment 1-10 as test specimen 1-10, using being obtained in comparative example 1-12 The mascara for obtaining is used as control sample 1-12.
Test method:Choose areal, the age be 18-45 one full year of life, sensitiveness skin quality, easily small pox long women white collar Subject 2200, is divided into 22 groups, respectively numbering 1-22.Wherein, 1-10 groups subject uses test specimen 1- respectively 10,11-22 groups subject then uses control sample 1-12 respectively.
1. use test specimen 1-10 and each 2mL of control sample 1-12, corresponds to subject by corresponding sample uniform application In the experience for after face, smearing, recording sample of the every group of subject to being used, project of investigating includes allergic phenomena, protects After wet effect, 15min small pox anti-inflammatory situation and carrying out use rear small pox healing state.
2. every group of subject is sooner or later each to smear using above-mentioned test method after face cleaning is carried out using identical burnisher Successively, persistently using 3 months after, observe and record anti-acne effect, acne print desalination situation and blackhead-removing situation (with every group 95% and the subject of the above there is change at aspects such as anti-acne, acne print desalination, blackhead-removings and be defined).
Result of the test:The experience of subject's 1-22 groups is as shown in table 2;Anti-acne effect, the acne print of subject's 1-22 groups Desalination situation and blackhead-removing situation are as shown in table 3.As shown in Table 2, test specimen 1-10 has excellent moistening effect, disappears , and in use, there is not allergic phenomena in inflammation effect and the effect of rapid healing small pox, clear not sticky texture, The crowd for being adapted to all ages and classes stage and sensitiveness skin quality uses.As shown in Table 3, test specimen 1-10 have excellent anti-acne, Desalination acne print, removal blackhead effect, and control sample 1-12 to subject's anti-acne, acne print desalination, blackhead-removing do not occur compared with Good contribution.
The experience of the subject's 1-22 groups of table 2
The anti-acne effect of the subject's 1-22 groups of table 3, acne print desalination situation and blackhead-removing situation
Test the experiment of two even results
Test specimen:Using the mascara obtained in embodiment 1-10 as test specimen 1-10, using comparative example 2-3, contrast The mascara obtained in example 12 is used as control sample 1-3.
Test method:From each taking-up 50mL in test specimen 1-10, control sample 1-3, numbering 1-13 groups, Xiang Qi respectively Middle instillation 0.1mL methyl orange reagents, after the mixer stirring 10s of 50rpm rotating speeds, the sample of the different groups of taking-up 1mL, and It is even to be applied to etc. in the blank sheet of paper of whiteness, compare the uniformity coefficient that each group scribbles color on different sample blank sheet of paper.
Result of the test:It is in uniform orange on blank sheet of paper after being smeared through test specimen 1-10, and is coated with control sample 1-3 Blank sheet of paper on different degrees of non-uniform phenomenon is presented respectively, wherein, scribble degree of irregularity on the blank sheet of paper of control sample 3 most For serious, the degree of irregularity for scribbling the blank sheet of paper of control sample 1 is more serious, scribbles the uneven journey of the blank sheet of paper of control sample 2 Degree takes second place.
The above is only the preferred embodiment of the present invention, and protection scope of the present invention is not limited merely to above-mentioned implementation Example, all technical schemes belonged under thinking of the present invention belong to protection scope of the present invention.It should be pointed out that for the art Those of ordinary skill for, some improvements and modifications without departing from the principles of the present invention, these improvements and modifications Should be regarded as protection scope of the present invention.

Claims (6)

1. a kind of anti-acne gel, it is characterised in that the component including following weight/mass percentage composition:
First solvent 15-50%;
Salicylic acid 0.3-3%;
Skin conditioning agent 0.7-14%;
Thickener 0.8-3%;
Camphor 0.05-1%;
Melaleuca alternifolia leaf oil 0.05-0.5%;
Balance of water and preservative;
First solvent includes the water of 5wt% and the ethanol of 95wt%;The skin conditioning agent includes hamamelis extract One or more in mixture, Aloe Barbadensis Miller extract mixtures, tea extract mixture;The thickener includes 10-20wt% polyacrylamides, 70-88wt% water, 1-5wt% C13-14 isoparaffins, 1-5wt% laureths -7.
2. anti-acne gel according to claim 1, it is characterised in that the component including following weight/mass percentage composition:
First solvent 15-50%;
Salicylic acid 0.3-3%;
Skin conditioning agent 0.7-14%;
Thickener 0.8-3%;
Camphor 0.05-1%;
Melaleuca alternifolia leaf oil 0.05-0.5%;
Balance of water and preservative;
First solvent includes the water of 5wt% and the ethanol of 95wt%;The skin conditioning agent chooses 0.5-8% hamamelis Extract mixtures, 0.1-3% Aloe Barbadensis Millers extract mixtures, 0.1-3% tea extract mixtures;The thickener Including 10-20wt% polyacrylamides, 70-88wt% water, 1-5wt% C13-14 isoparaffins, 1-5wt% laureths -7.
3. anti-acne gel according to claim 2, it is characterised in that the component including following weight/mass percentage composition:
First solvent 15-50%;
Salicylic acid 0.3-3%;
Hamamelis extract mixtures 0.5-8%;
Aloe Barbadensis Miller extract mixtures 0.1-3%;
Tea extract mixture 0.1-3%;
Thickener 0.8-3%;
Camphor 0.05-1%;
Melaleuca alternifolia leaf oil 0.05-0.5%;
Balance of water and preservative;
First solvent includes the water of 5wt% and the ethanol of 95wt%;The hamamelis extract mixtures include 77.5- The water of 79.45wt%, 20wt% butanediols, 0.05-2.0wt% hamamelis extract, 0.5wt% Phenoxyethanols;Draw in the storehouse Rope Folium Aloe extract mixture include 79.5-84.5wt% water, 10wt% butanediols, 5-10wt% aloe barbadensis Millers leaf extract, 0.5wt% Phenoxyethanols;The tea extract mixture includes 69.4wt% water, 29.6-30wt% butanediols, 0.1-0.5wt% Tea extract, 0.5wt% Phenoxyethanols;The thickener includes 10-20wt% polyacrylamides, 70-88wt% water, 1-5wt% C13-14 isoparaffins, 1-5wt% laureths -7.
4. anti-acne gel according to claim 3, it is characterised in that the component including following weight/mass percentage composition:
First solvent 30-50%;
Salicylic acid 1.5-3%;
Hamamelis extract mixtures 5-8%;
Aloe Barbadensis Miller extract mixtures 0.8-3%;
Tea extract mixture 2.2-3%;
Thickener 2-3%;
Camphor 0.5-1%;
Melaleuca alternifolia leaf oil 0.3-0.5%;
First solvent includes the water of 5wt% and the ethanol of 95wt%;The hamamelis extract mixtures include 77.5- The water of 79.45wt%, 20wt% butanediols, 0.05-2.0wt% hamamelis extract, 0.5wt% Phenoxyethanols;Draw in the storehouse Rope Folium Aloe extract mixture include 79.5-84.5wt% water, 10wt% butanediols, 5-10wt% aloe barbadensis Millers leaf extract, 0.5wt% Phenoxyethanols;The tea extract mixture includes 69.4wt% water, 29.6-30wt% butanediols, 0.1-0.5wt% Tea extract, 0.5wt% Phenoxyethanols;The thickener includes 10-20wt% polyacrylamides, 70-88wt% water, 1-5wt% C13-14 isoparaffins, 1-5wt% laureths -7.
5. a kind of preparation technology of anti-acne gel as described in claim 4, it is characterised in that comprise the following steps:
Step one, 5wt% water, 95wt% ethanol are sufficiently mixed, and form the first solvent;
Step 2, by 77.5-79.45wt% water, 20wt% butanediols, 0.05-2.0wt% hamamelis extract, 0.5wt% benzene Oxyethanol is sufficiently mixed, and forms hamamelis extract mixtures;
Step 3, by 79.5-84.5wt% water, 10wt% butanediols, 5-10wt% aloe barbadensis Millers leaf extract, 0.5wt% benzene oxygen Ethanol is sufficiently mixed, and forms Aloe Barbadensis Miller extract mixtures;
Step 4,69.4wt% water, 29.6-30wt% butanediols, 0.1-0.5wt% tea extracts, 0.5wt% Phenoxyethanols are filled Divide mixing, form tea extract mixture;
Step 5, by 10-20wt% polyacrylamides, 70-88wt% water, 1-5wt% C13-14 isoparaffins, 1-5wt% laruyl alcohols Polyethers -7 is sufficiently mixed, and forms thickener;
Step 6, first solvent of the 15-50% obtained in step one is sufficiently mixed with the salicylic acid of 0.3-3%, forms bigcatkin willow Acid solution;
Step 7, heats water to 78-80 DEG C, and 40-45 DEG C is cooled to after insulation half an hour, then at wherein adding by step 5 The salicylic acid solution of acquisition, is sufficiently mixed, and forms bigcatkin willow acid hydrate;
Step 8, obtains in the hamamelis extract mixtures that will be prepared in 0.5-8% step 2,0.1-3% step 3 The tea extract mixture obtained in the Aloe Barbadensis Miller extract mixtures, the 0.1-3% step 4 that obtain is added to step 7 In the bigcatkin willow acid hydrate of acquisition, dispersed with stirring is uniform;0.05-0.5% Melaleuca alternifolias leaf oil, 0.05-1% camphor trees are added afterwards Brain, is sufficiently mixed;The thickener obtained in 0.8-3% step 5 is added, is sufficiently stirred for, be eventually adding preservative, dispersed with stirring Uniformly, finished product, detection, discharging are obtained.
6. the preparation technology of anti-acne gel according to claim 5, it is characterised in that the preservative includes 0.3-1wt% Sodium Benzoate.
CN201710019779.5A 2017-01-11 2017-01-11 Anti-acne gel and its preparation technology Pending CN106727154A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648099A (en) * 2017-09-30 2018-02-02 朱耀灯 A kind of clear acne of oil-control repairs Essence
CN108272655A (en) * 2018-03-15 2018-07-13 广州普立森生物科技有限公司 The high moisture saver mask Essence of tremella polysaccharides and facial mask and preparation method thereof

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CN105434290A (en) * 2016-01-12 2016-03-30 中国热带农业科学院农产品加工研究所 Tea tree hydrosol acne-removing gel mask and preparation method thereof
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648099A (en) * 2017-09-30 2018-02-02 朱耀灯 A kind of clear acne of oil-control repairs Essence
CN108272655A (en) * 2018-03-15 2018-07-13 广州普立森生物科技有限公司 The high moisture saver mask Essence of tremella polysaccharides and facial mask and preparation method thereof

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Application publication date: 20170531