CN106715695B - 用于治疗和诊断的微rna和包含所述微rna的组合物 - Google Patents

用于治疗和诊断的微rna和包含所述微rna的组合物 Download PDF

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CN106715695B
CN106715695B CN201580018229.0A CN201580018229A CN106715695B CN 106715695 B CN106715695 B CN 106715695B CN 201580018229 A CN201580018229 A CN 201580018229A CN 106715695 B CN106715695 B CN 106715695B
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mir
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expression
receptor
antibody
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CN106715695A (zh
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A.陈
O.伊斯勒
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Yeda Research and Development Co Ltd
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CN201580018229.0A 2014-02-05 2015-02-05 用于治疗和诊断的微rna和包含所述微rna的组合物 Active CN106715695B (zh)

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US201461935912P 2014-02-05 2014-02-05
US61/935912 2014-02-05
PCT/IL2015/050132 WO2015118537A2 (en) 2014-02-05 2015-02-05 Micro-rnas and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions

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US (3) US10125365B2 (cg-RX-API-DMAC7.html)
EP (1) EP3102679B1 (cg-RX-API-DMAC7.html)
JP (3) JP2017506228A (cg-RX-API-DMAC7.html)
CN (2) CN106715695B (cg-RX-API-DMAC7.html)
CA (1) CA2936158C (cg-RX-API-DMAC7.html)
IL (1) IL246942B (cg-RX-API-DMAC7.html)
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EP2739736B1 (en) 2011-08-04 2017-04-19 Yeda Research and Development Co. Ltd. Mir-135 and compositions comprising same for the treatment of serotonin associated medical conditions
WO2015118537A2 (en) 2014-02-05 2015-08-13 Yeda Research And Development Co. Ltd. Micro-rnas and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions
JP7012310B2 (ja) * 2017-02-15 2022-02-14 国立研究開発法人医薬基盤・健康・栄養研究所 精神疾患モデル動物およびその製造方法
AU2018358016A1 (en) * 2017-11-03 2020-05-07 Interna Technologies B.V. MiRNA molecule, equivalent, antagomir, or source thereof for treating and/or diagnosing a condition and/or a disease associated with neuronal deficiency or for neuronal (re)generation
JP7268026B2 (ja) 2017-12-05 2023-05-02 サノビオン ファーマシューティカルズ インク 非ラセミ混合物およびその使用
CN112236138B (zh) 2017-12-05 2024-05-31 赛诺维信制药公司 晶体形式及其制备方法
CN108409851B (zh) * 2018-01-29 2020-12-08 上海交通大学 肾细胞癌中高水平表达的蛋白及其应用
CA3019970A1 (en) * 2018-10-05 2020-04-05 Fang Liu Methods for diagnosing or treating post-traumatic stress disorder, and compositions therefor
TWI703218B (zh) * 2019-01-19 2020-09-01 高雄榮民總醫院 生物標記用以診斷第二型雙極症的用途
EP3980009A4 (en) 2019-06-04 2023-07-05 Sunovion Pharmaceuticals Inc. MODIFIED RELEASE FORMULATIONS AND ASSOCIATED USES
EP4028507A4 (en) * 2019-09-10 2023-10-18 The Board of Trustees of the Leland Stanford Junior University Functional neuromodulatory assembloids
CN110585197B (zh) * 2019-09-26 2023-02-17 上海交通大学 多巴胺受体拮抗剂泰尔登在治疗急性髓系白血病中的应用
CN111172274B (zh) * 2020-01-22 2021-10-15 清华大学 Synaptotagmin-7在双向情感障碍诊断和治疗中的用途
CN111440861B (zh) * 2020-04-01 2022-11-04 上海市精神卫生中心（上海市心理咨询培训中心） 甲基化的miR-124基因在制备用于诊断抑郁症的标志物中的用途
EP4277635A4 (en) * 2021-01-18 2024-12-25 Yeda Research and Development Co. Ltd MODIFIED MIR-135, CONJUGATED FORM THEREOF, AND USES THEREOF
KR102570458B1 (ko) * 2021-01-21 2023-08-24 전남대학교산학협력단 여성의 우울증 위험도 예측용 바이오마커, 상기 바이오마커를 이용한 여성의 우울증 위험도 진단에 대한 정보제공방법 및 진단키트
JP7748047B2 (ja) * 2021-08-23 2025-10-02 国立研究開発法人産業技術総合研究所 唾液中のうつ病バイオマーカー
CN114292851B (zh) * 2022-01-12 2023-08-08 徐州医科大学 抑制Cnr1基因表达的干扰序列、shRNA慢病毒载体及构建方法和应用
CN117737246B (zh) * 2024-02-01 2025-01-28 首都医科大学附属北京天坛医院 Plcb1基因作为生物标志物在侵袭性垂体腺瘤中的应用

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