CN106714804A - 用于预测dlbcl对用btk抑制剂进行的治疗的响应的生物标志 - Google Patents

用于预测dlbcl对用btk抑制剂进行的治疗的响应的生物标志 Download PDF

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Publication number
CN106714804A
CN106714804A CN201580049596.7A CN201580049596A CN106714804A CN 106714804 A CN106714804 A CN 106714804A CN 201580049596 A CN201580049596 A CN 201580049596A CN 106714804 A CN106714804 A CN 106714804A
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dlbcl
lymphoma
modification
inhibitor
cell
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卡尔·施魏格霍费尔
卡尔·埃克特
旭平·郭
贝蒂·张
达林·博普雷
张宏杰
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Pharmacyclics LLC
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Pharmacyclics LLC
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  • Bioinformatics & Cheminformatics (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201580049596.7A 2014-08-01 2015-07-31 用于预测dlbcl对用btk抑制剂进行的治疗的响应的生物标志 Pending CN106714804A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462032430P 2014-08-01 2014-08-01
US62/032,430 2014-08-01
US201562119668P 2015-02-23 2015-02-23
US62/119,668 2015-02-23
US201562127484P 2015-03-03 2015-03-03
US62/127,484 2015-03-03
PCT/US2015/043300 WO2016019341A1 (en) 2014-08-01 2015-07-31 Biomarkers for predicting response of dlbcl to treatment with a btk inhibitor

Publications (1)

Publication Number Publication Date
CN106714804A true CN106714804A (zh) 2017-05-24

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Country Link
US (1) US20160032404A1 (enExample)
EP (1) EP3185870A4 (enExample)
JP (1) JP2017523188A (enExample)
KR (1) KR20170042614A (enExample)
CN (1) CN106714804A (enExample)
AU (1) AU2015296010A1 (enExample)
BR (1) BR112017001677A2 (enExample)
CA (1) CA2955744A1 (enExample)
IL (1) IL250221A0 (enExample)
MX (1) MX2017001302A (enExample)
RU (1) RU2017106794A (enExample)
SG (1) SG11201700774UA (enExample)
WO (1) WO2016019341A1 (enExample)

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CN110996972A (zh) * 2017-06-08 2020-04-10 恩立夫克治疗有限责任公司 用于癌症治疗的治疗性凋亡细胞
US11500112B2 (en) * 2018-10-10 2022-11-15 Symetrica Limited Gamma-ray spectrum classification

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KR101580714B1 (ko) 2010-06-03 2016-01-04 파마싸이클릭스 엘엘씨 브루톤 티로신 인산화효소(ｂｔｋ)의 억제제의 용도
BR112015001690A2 (pt) 2012-07-24 2017-11-07 Pharmacyclics Inc mutações associadas com a resistência a inibidores da tirosina quinase de bruton (btk)
WO2016071770A2 (en) * 2014-11-05 2016-05-12 Janssen Pharmaceutica Nv Biological markers for identifying ibrutinib resistance in patients having mantle cell lymphoma and methods of using the same
PT3699181T (pt) 2014-11-16 2023-04-05 Array Biopharma Inc Forma cristalina de hidrogenossulfato de (s)-n-(5-((r)-2-(2,5-difluorofenil)-pirrolidin-1-il)-pirazolo[1,5-a]pirimidin-3-il)-3-hidroxipirrolidina-1-carboxamida
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TN2018000138A1 (en) 2015-10-26 2019-10-04 Array Biopharma Inc Point mutations in trk inhibitor-resistant cancer and methods relating to the same
CN109414442B (zh) 2016-04-04 2024-03-29 洛克索肿瘤学股份有限公司 一种化合物的液体制剂
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JOP20190092A1 (ar) 2016-10-26 2019-04-25 Array Biopharma Inc عملية لتحضير مركبات بيرازولو[1، 5-a]بيريميدين وأملاح منها
JP7356351B2 (ja) 2016-12-12 2023-10-04 エクセラ・バイオサイエンシーズ・インコーポレイテッド マイクロキャピラリーアレイを使用したスクリーニングのための方法およびシステム
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CZ2017787A3 (cs) 2017-12-08 2019-06-19 Zentiva, K.S. Farmaceutické kompozice obsahující ibrutinib
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US11500112B2 (en) * 2018-10-10 2022-11-15 Symetrica Limited Gamma-ray spectrum classification

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EP3185870A4 (en) 2018-06-20
CA2955744A1 (en) 2016-02-04
BR112017001677A2 (pt) 2018-07-17
RU2017106794A (ru) 2018-09-03
SG11201700774UA (en) 2017-02-27
RU2017106794A3 (enExample) 2019-02-27
MX2017001302A (es) 2017-10-11
US20160032404A1 (en) 2016-02-04
AU2015296010A1 (en) 2017-02-02
EP3185870A1 (en) 2017-07-05
KR20170042614A (ko) 2017-04-19
WO2016019341A1 (en) 2016-02-04
JP2017523188A (ja) 2017-08-17
IL250221A0 (en) 2017-03-30

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