CN106659676A - 一种罗哌卡因缓释凝胶制剂及其制备与应用 - Google Patents
一种罗哌卡因缓释凝胶制剂及其制备与应用 Download PDFInfo
- Publication number
- CN106659676A CN106659676A CN201580038632.XA CN201580038632A CN106659676A CN 106659676 A CN106659676 A CN 106659676A CN 201580038632 A CN201580038632 A CN 201580038632A CN 106659676 A CN106659676 A CN 106659676A
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- CN
- China
- Prior art keywords
- ropivacaine
- gel
- sustained
- release gel
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
罗哌卡因缓释凝胶制剂、其制备方法及用途，所述凝胶制剂包括1‑20wt％的罗哌卡因、14‑22wt％的泊洛沙姆407和余量的水或盐溶液。
Description
PCT国内申请，说明书已公开。
Claims (34)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2014106181617 | 2014-11-05 | ||
| CN201410618161 | 2014-11-05 | ||
| PCT/CN2015/093883 WO2016070826A1 (zh) | 2014-11-05 | 2015-11-05 | 一种罗哌卡因缓释凝胶制剂及其制备与应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106659676A true CN106659676A (zh) | 2017-05-10 |
Family
ID=55908605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580038632.XA Pending CN106659676A (zh) | 2014-11-05 | 2015-11-05 | 一种罗哌卡因缓释凝胶制剂及其制备与应用 |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN106659676A (zh) |
| WO (1) | WO2016070826A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116172943B (zh) * | 2023-02-15 | 2024-01-26 | 上海市肿瘤研究所 | 一种可注射的缓释凝胶制剂及其制备与应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020013331A1 (en) * | 2000-06-26 | 2002-01-31 | Williams Robert O. | Methods and compositions for treating pain of the mucous membrane |
| CN103816111B (zh) * | 2014-02-26 | 2016-08-17 | 中国人民解放军第二军医大学 | 一种罗哌卡因纳米脂质载体温敏原位凝胶及其制备方法 |
-
2015
- 2015-11-05 CN CN201580038632.XA patent/CN106659676A/zh active Pending
- 2015-11-05 WO PCT/CN2015/093883 patent/WO2016070826A1/zh active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016070826A1 (zh) | 2016-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170510 |
|
| WD01 | Invention patent application deemed withdrawn after publication |