CN106620279A

CN106620279A - Traditional Chinese medicine composition for treating haemonchus contortus of sheep

Info

Publication number: CN106620279A
Application number: CN201611136769.1A
Authority: CN
Inventors: 张俊清; 张明
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-12-12
Filing date: 2016-12-12
Publication date: 2017-05-10

Abstract

The invention discloses a traditional Chinese medicine composition for treating haemonchus contortus of sheep and belongs to the technical field of traditional Chinese veterinary medicines. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 10 to 25 parts of fructus ulmi macrocarpae, 12 to 25 parts of butea monosperma, 10 to 24 parts of fructus quisqualis shell, 6 to 20 parts of sargentg loryvine stem, 5 to 20 parts of fructus mume, 3 to 12 parts of black pepper, 10 to 25 parts of wax gourd peel, 9 to 25 parts of fried semen euryales, 6 to 20 parts of semen myristicae, 6 to 18 parts of honey processed radix astragali seu hedysari, 30 to 50 parts of Chinese incarvilla herb, 8 to 20 parts of alcohol processed rhizoma polygonati, 6 to 18 parts of caulis dendrobii and 10 to 25 parts of honey processed liquorice root. The traditional Chinese medicine composition disclosed by the invention has the characteristics of killing and expelling parasites, benefiting qi and nourishing blood, warming spleen and stopping diarrhea and the like, can be used for completely killing the parasites, has a safe medical effect and has no toxic or side effect in clinical application.

Description

A kind of Chinese medicine composition for treating sheep haemonchiasis

Technical field

The invention belongs to technical field of Chinese veterinary medicine, in particular, belongs to a kind of Chinese medicine group for treating sheep haemonchiasis Compound.

Background technology

Sheep haemonchiasis in prior art, also known as haemonchus contortus, in parasite classification Mao Yuanke, blood lance is belonged to Category, polypide colonizes in sheep fourth stomach and small intestine, and polypide is superfine to have band and longitudinal ridge in hair-like on body surface skin, cervical papilla is very Significantly, the tapering oral capsule of polypide head end is little, have a thatch shape horny tooth in oral capsule.Female adult polypide due to white reproductive organs with contain The red intestinal tube of blood mutually surround, and outward appearance red and white is formed, so referred to as twisted mawworm.The disease can be sent out throughout the year It is raw, but it is more to be fallen ill with spring.

Haemonchiasis because：Worm's ovum pollution colony house, forage grass, the careless pasture discharged by ill domestic animal, nematode reproductive capacity is strong, grows Intermediate host is not needed in journey, the adaptability and resistance of worm's ovum and larva environment to external world is strong, and being difficult to be destroyed makes same group sheep Mutually infection, and scabies secondary infection other enterogastric diseases, the dosage for causing sheep husbandry increases cost increase, causes feed conversion Rate declines marketing time and extends.As prevented and treated the incidence of disease of animal not in time up to more than 70%, death toll accounts for the 40% of the incidence of disease More than, cause heavy economic losses to aquaculture.

Twisted mawworm primary symptom:Sick sheep down in spirits, two without god, by hair is thick disorderly, poor growth progressive emaciation, physique is empty It is weak not like to walk about out to herd not catching up with group.The visual mucosal pallor anaemia such as eye conjunctiva, oral mucosa.The slightly lower pulse of body temperature is weak, chest and abdomen Portion's oedema especially touch obvious with the oedema of lower jaw bottom when have fluctuation.Sick sheep indigestion anorexia drinking-water increases The soft shapeless prolongation excreta with the course of disease of loose and watery stool is in black gruel sample and is mixed with downright bad mucus discharge, is covered in sick sheep anus Between door periphery and two strands.Polypide parasitized breeding is quick, and parasitic quantity is mostly this sick distinguishing feature, and parasitic quantity is hundreds of at least Bar, course of disease time longer sick sheep detects polypide up to thousands of in abomasum, little enteral.This disease as treated not in time, sick sheep because Malnutrition sinks into cachexy and dies of exhaustion to die.

Twisted mawworm diagnosis:Root Ju clinical examination sick sheep symptom, Binding experiment room sick sheep excrement brine flotation, inspection Make a definite diagnosis by going out twisted mawworm worm's ovum.

Mostly based on chemicals metrifonate, ivermectin, foregoing pharmaceutical is facing the twisted mawworm of prior art treatment sheep There is the liver to domestic animal, gall-bladder, kidney organ's stimulation infringement in bed greatly, drug accumulation residual quantity is high, and use for a long time can be produced Raw drug resistance, is required for many course for the treatment of repeated drug takings to can be only achieved the effect for thoroughly dispelling polypide.Have not using after said medicine The medicine phase, typically at 28-35 days or so, can not butcher edible in the off-drug period, dam is forbidden to use in nursing period.Some anthelmintic drugs Promote smooth muscle spasm to cause pregnant sheep to miscarry sometimes in clinical treatment, inaccurate dose is grasped to thin and weak ill domestic animal dosage slightly larger Sick sheep can be caused to be poisoned to death.

The content of the invention

The present invention gives a kind of Chinese traditional medicine composition for treating sheep haemonchiasis to efficiently solve above technical problem Thing.

A kind of Chinese medicine composition for treating sheep haemonchiasis of the present invention, it is characterised in that constitute by following weight portion： Fructus ulmi 10-25 parts, palas 12-25 parts, fruit of Rangoon creeper's shell 10-24 parts, Sargent gloryvine 6-20 parts, dark plum 5-20 parts, black pepper 3-12 parts, winter Melon skin 10-25 parts, stir-baked SEMEN EURYALES 9-25 parts, nutmeg 6-20 parts, sweet Radix Astragali (processed) 6-18 parts, Chinese Incarvilla Herb 30-50 parts, stir-baked RHIZOMA POLYGONATI with yellow rice wine 8-20 Part, stem of noble dendrobium 6-18 parts, Radix Glycyrrhizae (processed with honey) 10-25 parts.

The Chinese medicine composition of sheep haemonchiasis is treated in accordance with the above, it is preferable that constituted by following weight portion：Fructus ulmi 10 Part, 12 parts of palas, 10 parts of fruit of Rangoon creeper's shell, 6 parts of Sargent gloryvine, 5 parts of dark plum, 3 parts of black pepper, 10 parts of waxgourd peel, 9 parts of stir-baked SEMEN EURYALES, Pork and beans Cool 6 parts, sweet 6 parts of Radix Astragali (processed), 30 parts of Chinese Incarvilla Herb, 8 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 6 parts of the stem of noble dendrobium, 10 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of sheep haemonchiasis is treated in accordance with the above, it is preferable that constituted by following weight portion：Fructus ulmi 25 Part, 25 parts of palas, 24 parts of fruit of Rangoon creeper's shell, 20 parts of Sargent gloryvine, 20 parts of dark plum, 12 parts of black pepper, 25 parts of waxgourd peel, 25 parts of stir-baked SEMEN EURYALES, 20 parts of nutmeg, sweet 18 parts of Radix Astragali (processed), 50 parts of Chinese Incarvilla Herb, 20 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 18 parts of the stem of noble dendrobium, 25 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of sheep haemonchiasis is treated in accordance with the above, it is preferable that constituted by following weight portion：Fructus ulmi 12 Part, 13 parts of palas, 12 parts of fruit of Rangoon creeper's shell, 8 parts of Sargent gloryvine, 7 parts of dark plum, 5 parts of black pepper, 12 parts of waxgourd peel, 11 parts of stir-baked SEMEN EURYALES, Pork and beans Cool 8 parts, sweet 9 parts of Radix Astragali (processed), 32 parts of Chinese Incarvilla Herb, 10 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 7 parts of the stem of noble dendrobium, 12 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of sheep haemonchiasis is treated in accordance with the above, it is preferable that constituted by following weight portion：Fructus ulmi 14 Part, 15 parts of palas, 13 parts of fruit of Rangoon creeper's shell, 9 parts of Sargent gloryvine, 8 parts of dark plum, 6 parts of black pepper, 14 parts of waxgourd peel, 13 parts of stir-baked SEMEN EURYALES, Pork and beans Cool 10 parts, sweet 11 parts of Radix Astragali (processed), 35 parts of Chinese Incarvilla Herb, 11 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 9 parts of the stem of noble dendrobium, 13 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of sheep haemonchiasis is treated in accordance with the above, it is preferable that constituted by following weight portion：Fructus ulmi 15 Part, 17 parts of palas, 15 parts of fruit of Rangoon creeper's shell, 11 parts of Sargent gloryvine, 10 parts of dark plum, 7 parts of black pepper, 16 parts of waxgourd peel, 15 parts of stir-baked SEMEN EURYALES, meat 12 parts of cardamom, sweet 12 parts of Radix Astragali (processed), 39 parts of Chinese Incarvilla Herb, 13 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 11 parts of the stem of noble dendrobium, 15 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of sheep haemonchiasis is treated in accordance with the above, it is preferable that constituted by following weight portion：Fructus ulmi 17 Part, 19 parts of palas, 17 parts of fruit of Rangoon creeper's shell, 13 parts of Sargent gloryvine, 12 parts of dark plum, 9 parts of black pepper, 18 parts of waxgourd peel, 17 parts of stir-baked SEMEN EURYALES, meat 14 parts of cardamom, sweet 13 parts of Radix Astragali (processed), 42 parts of Chinese Incarvilla Herb, 15 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 12 parts of the stem of noble dendrobium, 16 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of sheep haemonchiasis is treated in accordance with the above, it is preferable that constituted by following weight portion：Fructus ulmi 19 Part, 20 parts of palas, 19 parts of fruit of Rangoon creeper's shell, 15 parts of Sargent gloryvine, 14 parts of dark plum, 10 parts of black pepper, 20 parts of waxgourd peel, 19 parts of stir-baked SEMEN EURYALES, 16 parts of nutmeg, sweet 15 parts of Radix Astragali (processed), 45 parts of Chinese Incarvilla Herb, 16 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 14 parts of the stem of noble dendrobium, 18 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of sheep haemonchiasis is treated in accordance with the above, it is preferable that constituted by following weight portion：Fructus ulmi 21 Part, 22 parts of palas, 21 parts of fruit of Rangoon creeper's shell, 18 parts of Sargent gloryvine, 16 parts of dark plum, 11 parts of black pepper, 22 parts of waxgourd peel, 21 parts of stir-baked SEMEN EURYALES, 18 parts of nutmeg, sweet 16 parts of Radix Astragali (processed), 47 parts of Chinese Incarvilla Herb, 17 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 15 parts of the stem of noble dendrobium, 20 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of sheep haemonchiasis is treated in accordance with the above, it is preferable that constituted by following weight portion：Fructus ulmi 23 Part, 24 parts of palas, 23 parts of fruit of Rangoon creeper's shell, 19 parts of Sargent gloryvine, 18 parts of dark plum, 12 parts of black pepper, 24 parts of waxgourd peel, 23 parts of stir-baked SEMEN EURYALES, 19 parts of nutmeg, sweet 17 parts of Radix Astragali (processed), 48 parts of Chinese Incarvilla Herb, 18 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 17 parts of the stem of noble dendrobium, 23 parts of Radix Glycyrrhizae (processed with honey).

Property of medicine effect of each component in the Chinese medicine composition of the treatment sheep haemonchiasis of the present invention：

Fructus ulmi:Nature and flavor:Acrid, bitter, warm.Return through:Enter liver, spleen, stomach.Effect:It is killing insect and eliminating accumulation, warming spleen and stopping diarrha.Cure mainly:Kill Abdominal pain due to enterositosis and vermin mange caused by endoparasite such as roundworm, tapeworm.

Palas：Nature and flavor：Bitter, sweet, temperature.Return through：Return liver, stomach.Effect：Kill internal organ worm, pain relieving.Cure mainly：Kill and post in vivo Raw insect.

Fruit of Rangoon creeper's shell：Nature and flavor:Sweet, temperature.Return through：Returns spleen, stomach.Effect:Disappear long-pending desinsection, reinforcing spleen to promote digestion.Cure mainly:By parasitism Parasitosis such as roundworm, the abdominal pain due to enterositosis carcass that pinworm causes day by day is become thin, and weakness of the spleen and the stomach indigestion is caused to suffer from diarrhoea.

Sargent gloryvine:Nature and flavor:It is bitter, puckery, flat.Return through:Return stomach, large intestine channel.Effect:Relax the muscles and stimulate the blood circulation, clearing heat and detoxicating, disappear long-pending desinsection. Cure mainly:The stomachache that numbness contracture, killing roundworm, hookworm and the polypide blocking that rheumatism twitching pain of muscle causes causes.

Dark plum:Nature and flavor:Sour, puckery, temperature.Return through:Return liver, spleen and lung, large intestine channel.Effect:Astringe the lung to stop cough, relieving diarrhea with astringents, claming ascaris Pain relieving.Cure mainly:Chronic cough is more than, chronic diarrhea, protracted dysentery cause that body fluid deficiency, can play and promote the production of body fluid to quench thirst and worm caused by various parasites Product stomachache.The nature and flavor of dark plum are sour and astringent, enter stomach can promote the production of body fluid peace worm, worm meet it is sour and astringent then volt and it is motionless, kill effect beneficial to anthelmintic drug It is external with being excluded.

Black pepper:Nature and flavor:Pungent, heat.Return through:Enter large intestine channel.Effect:Warming spleen and stomach for dispelling cold, lower gas dissolving phlegm.Cure mainly:Insufficiency of the spleen stomach is weak The cold intestines that indigestion causes are had loose bowels；Fructus Piperis extract has destroying and expelling tenia to act on.Black pepper nature and flavor function is pungent fiber crops, and pungent fiber crops can It is easy to exclude polypide with the adsorption function for weakening polypide sucker.

Waxgourd peel：Nature and flavor：It is sweet, be slightly cold.Return through：Return lung, spleen, small intestinl channel.Effect：Clearing away heat and promoting diuresis, detumescence.Cure mainly：Oedema, Difficult urination, have loose bowels.

Stir-baked SEMEN EURYALES:Nature and flavor:Nature and flavor:It is sweet, puckery, flat.Return through:Returns spleen, kidney channel.Effect:Invigorating the spleen to arrest diarrhea, reinforcing the kidney and controlling noctural emission.Cure mainly: Insufficiency of the spleen caused by weakness of the spleen and the stomach transformation failure of spleen rushes down, endless diarrhea.

Nutmeg:Nature and flavor:Pungent, temperature.Return through:Returns spleen, stomach, large intestine channel.Effect:Relieving diarrhea with astringents, warming the middle warmer and descending qi.Cure mainly:By Weakness of the spleen and the stomach, transporting is lost the food stagnation caused by splenasthenic diarrhea and deficiency-cold in spleen and stomach caused by power and is not changed, and tripe abdomen pain is had loose bowels.

Sweet Radix Astragali (processed):Nature and flavor:Sweet, temperature.Return through:Return lung, the spleen channel.Effect:It is raw to use solid table, torr sore myogenic；Process with bowl spares, carry Rise healthy tendency, the work(of favourable water.Cure mainly:Tonifying middle-Jiao and Qi, tonifying Qi are simultaneous to help sun to cause for weakness of the spleen and the stomach, splenasthenic diarrhea collapse from qi deficiency Endless diarrhea void oedema

Chinese Incarvilla Herb:Nature and flavor:Sweet, light, temperature.Return through：Effect:Strengthening by means of tonics, damp dispelling and pain relieving.Cure mainly:Prolonged illness deficiency of vital energy and blood qi and blood Carcass weakness, lassitude that deficiency causes.

Stir-baked RHIZOMA POLYGONATI with yellow rice wine：Nature and flavor：It is sweet, flat.Return through：Returns spleen, lung channel.Effect：Tonifying middle-Jiao and Qi, moisten the lung and relieve the cough.Cure mainly：It is weakness of the spleen and the stomach Caused endless diarrhea plays astringing to arrest diarrhea and palace is supported bad One's spirits are drooping depressed, the lassitude for causing and moved less.

The stem of noble dendrobium:Nature and flavor:It is sweet, light, be slightly cold.Return through：Enter lung, stomach, kidney channel.Effect:Replenishing the vital essence and removing heat, promote the production of body fluid to quench thirst, zhuanggu mend It is empty, kind to drive cold numbness.Cure mainly：Nourishing the stomach-yin, born fluid, it is adaptable to which body fluid is injured or yin asthenia generating intrinsic heat, and tongue light is few without tongue, body fluid Etc. deficiency of stomach-Yin disease.This product is good at qi-restoratives.

Radix Glycyrrhizae (processed with honey):Nature and flavor:It is sweet, flat.Return through:Return 12 warps.Effect:Tonifying Qi and in, it is clearing heat and detoxicating, coordinating the drug actions of a prescription, slow Anxious pain relieving.Cure mainly:Coordinating the drug actions of a prescription, attenuating drug toxicity, warmly invigorating spleen and stomach are empty thanks to, strengthening QI of middle-JIAO is not enough strong carcass, alleviation are because of stomach The stomachache that enterospasm causes.

The principle of reatment of the present invention：It is desinsection parasite elimination, benefiting qi and nourishing blood, warming spleen and stopping diarrha.

Fang Xie：With fructus ulmi, palas, fruit of Rangoon creeper's shell, red Sheng as main ingredient in side, the polypide colonized in abomasum is killed；With crow Plum, black pepper be adjuvant, assist monarch drug in a prescription desinsection, parasite elimination, especially with the sour and astringent property of dark plum can with numb Paralysis polypides, prevent polypide activity It is set to be temporarily lost with locomitivity；The property of the pungent fiber crops of black pepper can release the adsorption function of polypide sucker, make polypide depart from stomach Wall is smoothly excreted；Tonifying Qi is played as adjutant with waxgourd peel, stir-baked SEMEN EURYALES, nutmeg, sweet Radix Astragali (processed), Chinese Incarvilla Herb, stir-baked RHIZOMA POLYGONATI with yellow rice wine, the stem of noble dendrobium The pale anaemia of conjunctiva caused because of parasitic infestation is treated in promoting circulation of blood, enriching yin of enriching blood, and is recovered the thin and weak physique of sick sheep and is promoted diet recovery Resistance, recovers the diarrhoea stomachache caused by gastrointestinal function is controlled because of Enterozoa, and dispelling dampness and promoting diuresis eliminates swelling；It is with Radix Glycyrrhizae (processed with honey) Make medicine, coordinating the drug actions of a prescription, relax the property of medicine, priming return through, each medicine of the above closes medicine and shares, and reaches and cures this sick purpose.

The beneficial effect of the present invention and prior art：The present invention middle pharmaceutical composition overcome the deficiencies in the prior art, The low shortcoming of He Zhi More rates, there is provided the Traditional Chinese medicine composition formula for treating sheep haemonchiasis a kind of evident in efficacy, safe and reliable.

It is to change that the Chinese medicine composition of the present invention treats the maximum difference of sheep haemonchiasis with existing chemical synthetic drug For many years on veterinary clinic expelling parasite medication outdated ideas, due to Long-Time Service chemosynthesis medicine treatment animal parasite disease, make Low into domestic animal non-specific immunity, particularly medicine is in, and carcass is interior to be remained and manure contamination environment, and to people meat is eaten Safety and environmental pollution work the mischief.

The present invention pharmaceutical composition adopt multi-flavor pure Chinese medicine composition, with Western medicine chemicals do not have it is unique excellent Gesture, both has functions that to kill twisted mawworm polypide, while and the effect that polypide discharges from sick sheep body can be promoted, it is of the invention Chinese medicine composition be unique in that in formula and select medicine targetedly from the medicine of the property with sour and astringent nature and flavor and pungent fiber crops, The twisted nematode polypide that paralysis is colonized in sick sheep abomasum is allowed to lose absorption and mobility, can quickly be excluded external. Disease liver, kidney are not damaged, remained, had no toxic side effect without drug accumulation, not developing immunity to drugs.Play and thoroughly kill and discharge worm The therapeutic effect of body, chemical expelling parasite medicine does not have conditioning engine body equilibrium between yin and yang, effect of the strong ill domestic animal body of help, the present invention The Chinese medicine composition for killing twisted mawworm there is to kill polypide there is the thin and weak body of the strong body recovery sick sheep of help again Matter, improves effect of carcass immunity, and treatment principle has essence different from chemical drug, and inaccurate appearance is grasped in chemical synthetic drug metering Easily cause and be poisoned to death, cause unnecessary economic loss.The Chinese medicine composition of the present invention solves above-mentioned deficiency can be reached The prevention effect treated both principal and secondary aspect of disease.

The present invention Chinese medicine composition it is easy to use, easily absorbed.Further preferred dosage form in improved technology scheme, is administered Approach simplicity is various can both to have gavaged administration, can also mix livestock free choice feeding of leaving in feed, use manpower and material resources sparingly easily Received by raiser.Composition medicine is easy to make storage and is used, suitably the wide popularization and application in Animal husbandry production practice, The Chinese medicine composition of the present invention has desinsection parasite elimination, benefiting qi and nourishing blood, warming spleen and stopping diarrha, fast quick-recovery sick sheep resistance, nontoxic secondary work With clinical practice is without any side effects.

Specific embodiment

Preferred embodiment 1

The Chinese medicine composition of the treatment sheep haemonchiasis of present embodiment, is constituted by following weight portion：10 parts of fructus ulmi, purple 12 parts of riveting, 10 parts of fruit of Rangoon creeper's shell, 6 parts of Sargent gloryvine, 5 parts of dark plum, 3 parts of black pepper, 10 parts of waxgourd peel, 9 parts of stir-baked SEMEN EURYALES, 6 parts of nutmeg, 6 parts of sweet Radix Astragali (processed), 30 parts of Chinese Incarvilla Herb, 8 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 6 parts of the stem of noble dendrobium, 10 parts of Radix Glycyrrhizae (processed with honey).

Preparation method one

Step one, mixing immersion：By 10 parts of fructus ulmi, 12 parts of palas, 10 parts of fruit of Rangoon creeper's shell, 6 parts of Sargent gloryvine, 5 parts of dark plum, black Hu 3 parts of green pepper, 10 parts of waxgourd peel, 9 parts of stir-baked SEMEN EURYALES, 6 parts of nutmeg, sweet 6 parts of Radix Astragali (processed), 30 parts of Chinese Incarvilla Herb, 8 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 6 parts of the stem of noble dendrobium, 10 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, is well mixed immersion：Each raw material, gross weight note are weighed by above-mentioned mass ratio For 1 part, 8 parts of purified waters, 40-50 DEG C of immersion 2h are added medicinal material is fully expanded；

Step 2, extraction：Using decocting method twice, by medicinal material and purified water, it is 0.1-0.2MPa to control steam pressure, plus Heat continues to boil 2h to after seething with excitement, and separates and takes out fried liquid, continues the purified water that 4 parts are added into medicinal material, controls steam pressure For 0.1-0.2MPa, after being heated to boiling, continue to boil 1.5h, merge fried liquid twice and be extract；

Step 3, concentration：Obtained extract is added and is concentrated in economic benefits and social benefits concentration tank, steam pressure concentrated in vacuo is 0.1MPa, an effect vacuum concentrator operating pressure is 0.04MPa, and temperature is 80 DEG C；Two effect inspissator operating pressures 0.06MPa, Temperature is 65 DEG C, and concentration time is 2.5-3.5h, when heat survey relative density is 1.17-1.20, obtains concentrate；

Step 4, alcohol precipitation：Concentrate is placed in Alcohol-settling tank, 95% ethanol is slowly added to in Alcohol-settling tank, contain ethanol Measure as 65%-70%, stir 30min, 4 DEG C of refrigerations stand 48h, be evaporated to relative density for 1.40-1.50, reclaim second Alcohol, that is, obtain alcohol extracting liquid；

Step 5, with liquid：To in Agitation Tank add 0.3-0.4 part purified waters, then sequentially add gained alcohol extract, 0.003 part of Sodium Benzoate, stirs to fully dissolving, the amount for adding purified water to be settled to 1 part, stirs 15min, and treatment sheep is obtained The traditional Chinese medicine oral liquid of haemonchiasis.

Preparation method two

Step one, by 10 parts of fructus ulmi, 12 parts of palas, 10 parts of fruit of Rangoon creeper's shell, 6 parts of Sargent gloryvine, 5 parts of dark plum, 3 parts of black pepper, winter 10 parts of melon skin, 9 parts of stir-baked SEMEN EURYALES, 6 parts of nutmeg, sweet 6 parts of Radix Astragali (processed), 30 parts of Chinese Incarvilla Herb, 8 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 6 parts of the stem of noble dendrobium, Radix Glycyrrhizae (processed with honey) 10 parts, every part of active compound quality is one gram, stirring, mixing in input mixer；Send in pulverizer and crush；

Step 2, the Chinese medicine composition after crushing is fitted in multi-function extractor, is added relative to 6 times of amounts of its quality Water, boil 3 hours, steam pressure is 0.6Mpa process, filter, obtain the first filtered fluid and filter residue；By the filter residue for obtaining again Add the water relative to 5 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, be filtrated to get the second filtered fluid and filter Slag；

Step 3, the first filtered fluid and the second filtered fluid are merged, concentration removes moisture and obtains dry cream, using ultra micro grinding Machine is crushed, and is crushed to acquisition Chinese medicine micropowders below 40-60 microns, and the composition for preparing is put in container or polybag Middle sealing is standby.

Preparation method three

Step one：By 10 parts of fructus ulmi, 12 parts of palas, 10 parts of fruit of Rangoon creeper's shell, 6 parts of Sargent gloryvine, 5 parts of dark plum, 3 parts of black pepper, winter 10 parts of melon skin, 9 parts of stir-baked SEMEN EURYALES, 6 parts of nutmeg, sweet 6 parts of Radix Astragali (processed), 30 parts of Chinese Incarvilla Herb, 8 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 6 parts of the stem of noble dendrobium, Radix Glycyrrhizae (processed with honey) 10 parts, it is well mixed, every part of active compound quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, is decocted 3 hours, the The secondary 6 times of weight that add water, decoct 2 hours；

Step 2, decoction liquor to be filtered and obtain filtrate after the dregs of a decoction, filtrate is concentrated into relative density for 1.23-1.33 (65 DEG C) Clear cream；

Mix in step 3, clear cream plus after appropriate amount of starch, be dried, crush and add appropriate amount of ethanol to make particle, it is dry, whole Grain, obtain final product composition grain preparation.

The usage and dosage of the Chinese medicine composition of the present embodiment：1st, oral liquid formulations usage and dosage：By sick sheep body weight 2g/kg agent Amount, is administered by perfusion clothes, and one time a day, is used in conjunction 4-8 days.2nd, powder preparation or granular preparation usage and dosage：By sick sheep body weight 3ml/kg dosage, is administered by perfusion clothes, and one time a day, is used in conjunction 4-8 days.Or according to the upper of present embodiment Chinese medicine composition After proportion relation is stated by Chinese medicine composition mixing immersion, with obtaining Chinese medicinal decoction after frying pan infusion, according to the body weight of ill domestic animal with And after the Chinese medicinal decoction of the state of an illness selection doses ill domestic animal is directly gavaged by stomach tube, one time a day, is used in conjunction 4-8 days.

Preferred embodiment 2

The Chinese medicine composition of the treatment sheep haemonchiasis of present embodiment, is constituted by following weight portion：25 parts of fructus ulmi, purple 25 parts of riveting, 24 parts of fruit of Rangoon creeper's shell, 20 parts of Sargent gloryvine, 20 parts of dark plum, 12 parts of black pepper, 25 parts of waxgourd peel, 25 parts of stir-baked SEMEN EURYALES, nutmeg 20 parts, sweet 18 parts of Radix Astragali (processed), 50 parts of Chinese Incarvilla Herb, 20 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 18 parts of the stem of noble dendrobium, 25 parts of Radix Glycyrrhizae (processed with honey).

Preparation method one

Step one, mixing immersion：By 25 parts of fructus ulmi, 25 parts of palas, 24 parts of fruit of Rangoon creeper's shell, 20 parts of Sargent gloryvine, 20 parts of dark plum, black 12 parts of pepper, 25 parts of waxgourd peel, 25 parts of stir-baked SEMEN EURYALES, 20 parts of nutmeg, sweet 18 parts of Radix Astragali (processed), 50 parts of Chinese Incarvilla Herb, 20 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, stone 18 parts of dry measure used in former times, 25 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, is well mixed immersion：Each raw material is weighed by above-mentioned mass ratio, always Weight is designated as 1 part, adds 8 parts of purified waters, 40-50 DEG C of immersion 2h medicinal material is fully expanded；

Preparation method two

Step one, by 25 parts of fructus ulmi, 25 parts of palas, 24 parts of fruit of Rangoon creeper's shell, 20 parts of Sargent gloryvine, 20 parts of dark plum, 12 parts of black pepper, 25 parts of waxgourd peel, 25 parts of stir-baked SEMEN EURYALES, 20 parts of nutmeg, sweet 18 parts of Radix Astragali (processed), 50 parts of Chinese Incarvilla Herb, 20 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 18 parts of the stem of noble dendrobium, honey 25 parts of honey-fried licorice root, every part of active compound quality is one gram, stirring, mixing in input mixer；Send in pulverizer and crush；

Preparation method three

Step one：By 25 parts of fructus ulmi, 25 parts of palas, 24 parts of fruit of Rangoon creeper's shell, 20 parts of Sargent gloryvine, 20 parts of dark plum, 12 parts of black pepper, 25 parts of waxgourd peel, 25 parts of stir-baked SEMEN EURYALES, 20 parts of nutmeg, sweet 18 parts of Radix Astragali (processed), 50 parts of Chinese Incarvilla Herb, 20 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 18 parts of the stem of noble dendrobium, honey 25 parts of honey-fried licorice root, is well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, decocts 3 little When, add water for the second time 6 times of weight, decocts 2 hours；

Preferred embodiment 3

The Chinese medicine composition of the treatment sheep haemonchiasis of present embodiment, is constituted by following weight portion：12 parts of fructus ulmi, purple 13 parts of riveting, 12 parts of fruit of Rangoon creeper's shell, 8 parts of Sargent gloryvine, 7 parts of dark plum, 5 parts of black pepper, 12 parts of waxgourd peel, 11 parts of stir-baked SEMEN EURYALES, nutmeg 8 Part, sweet 9 parts of Radix Astragali (processed), 32 parts of Chinese Incarvilla Herb, 10 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 7 parts of the stem of noble dendrobium, 12 parts of Radix Glycyrrhizae (processed with honey).

Preparation method one

Step one, mixing immersion：By 12 parts of fructus ulmi, 13 parts of palas, 12 parts of fruit of Rangoon creeper's shell, 8 parts of Sargent gloryvine, 7 parts of dark plum, black Hu 5 parts of green pepper, 12 parts of waxgourd peel, 11 parts of stir-baked SEMEN EURYALES, 8 parts of nutmeg, sweet 9 parts of Radix Astragali (processed), 32 parts of Chinese Incarvilla Herb, 10 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, the stem of noble dendrobium 7 Part, 12 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, is well mixed immersion：Each raw material, gross weight are weighed by above-mentioned mass ratio 1 part is designated as, adds 8 parts of purified waters, 40-50 DEG C of immersion 2h medicinal material is fully expanded；

Preparation method two

Step one, by 12 parts of fructus ulmi, 13 parts of palas, 12 parts of fruit of Rangoon creeper's shell, 8 parts of Sargent gloryvine, 7 parts of dark plum, 5 parts of black pepper, winter 12 parts of melon skin, 11 parts of stir-baked SEMEN EURYALES, 8 parts of nutmeg, sweet 9 parts of Radix Astragali (processed), 32 parts of Chinese Incarvilla Herb, 10 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 7 parts of the stem of noble dendrobium, honey are processed sweet 12 parts of grass, every part of active compound quality is one gram, stirring, mixing in input mixer；Send in pulverizer and crush；

Preparation method three

Step one：By 12 parts of fructus ulmi, 13 parts of palas, 12 parts of fruit of Rangoon creeper's shell, 8 parts of Sargent gloryvine, 7 parts of dark plum, 5 parts of black pepper, winter 12 parts of melon skin, 11 parts of stir-baked SEMEN EURYALES, 8 parts of nutmeg, sweet 9 parts of Radix Astragali (processed), 32 parts of Chinese Incarvilla Herb, 10 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 7 parts of the stem of noble dendrobium, honey are processed sweet 12 parts of grass, is well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, is decocted 3 hours, Add water for the second time 6 times of weight, decocts 2 hours；

Preferred embodiment 4

The Chinese medicine composition of the treatment sheep haemonchiasis of present embodiment, is constituted by following weight portion：14 parts of fructus ulmi, purple 15 parts of riveting, 13 parts of fruit of Rangoon creeper's shell, 9 parts of Sargent gloryvine, 8 parts of dark plum, 6 parts of black pepper, 14 parts of waxgourd peel, 13 parts of stir-baked SEMEN EURYALES, nutmeg 10 Part, sweet 11 parts of Radix Astragali (processed), 35 parts of Chinese Incarvilla Herb, 11 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 9 parts of the stem of noble dendrobium, 13 parts of Radix Glycyrrhizae (processed with honey).

Preparation method one

Step one, mixing immersion：By 14 parts of fructus ulmi, 15 parts of palas, 13 parts of fruit of Rangoon creeper's shell, 9 parts of Sargent gloryvine, 8 parts of dark plum, black Hu 6 parts of green pepper, 14 parts of waxgourd peel, 13 parts of stir-baked SEMEN EURYALES, 10 parts of nutmeg, sweet 11 parts of Radix Astragali (processed), 35 parts of Chinese Incarvilla Herb, 11 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, the stem of noble dendrobium 9 Part, 13 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, is well mixed immersion：Each raw material, gross weight are weighed by above-mentioned mass ratio 1 part is designated as, adds 8 parts of purified waters, 40-50 DEG C of immersion 2h medicinal material is fully expanded；

Preparation method two

Step one, by 14 parts of fructus ulmi, 15 parts of palas, 13 parts of fruit of Rangoon creeper's shell, 9 parts of Sargent gloryvine, 8 parts of dark plum, 6 parts of black pepper, winter 14 parts of melon skin, 13 parts of stir-baked SEMEN EURYALES, 10 parts of nutmeg, sweet 11 parts of Radix Astragali (processed), 35 parts of Chinese Incarvilla Herb, 11 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 9 parts of the stem of noble dendrobium, honey are processed 13 parts of Radix Glycyrrhizae, every part of active compound quality is one gram, stirring, mixing in input mixer；Send in pulverizer and crush；

Preparation method three

Step one：By 14 parts of fructus ulmi, 15 parts of palas, 13 parts of fruit of Rangoon creeper's shell, 9 parts of Sargent gloryvine, 8 parts of dark plum, 6 parts of black pepper, winter 14 parts of melon skin, 13 parts of stir-baked SEMEN EURYALES, 10 parts of nutmeg, sweet 11 parts of Radix Astragali (processed), 35 parts of Chinese Incarvilla Herb, 11 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 9 parts of the stem of noble dendrobium, honey are processed 13 parts of Radix Glycyrrhizae, is well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, decocts 3 little When, add water for the second time 6 times of weight, decocts 2 hours；

Preferred embodiment 5

The Chinese medicine composition of the treatment sheep haemonchiasis of present embodiment, is constituted by following weight portion：15 parts of fructus ulmi, purple 17 parts of riveting, 15 parts of fruit of Rangoon creeper's shell, 11 parts of Sargent gloryvine, 10 parts of dark plum, 7 parts of black pepper, 16 parts of waxgourd peel, 15 parts of stir-baked SEMEN EURYALES, nutmeg 12 parts, sweet 12 parts of Radix Astragali (processed), 39 parts of Chinese Incarvilla Herb, 13 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 11 parts of the stem of noble dendrobium, 15 parts of Radix Glycyrrhizae (processed with honey).

Preparation method one

Step one, mixing immersion：By 15 parts of fructus ulmi, 17 parts of palas, 15 parts of fruit of Rangoon creeper's shell, 11 parts of Sargent gloryvine, 10 parts of dark plum, black 7 parts of pepper, 16 parts of waxgourd peel, 15 parts of stir-baked SEMEN EURYALES, 12 parts of nutmeg, sweet 12 parts of Radix Astragali (processed), 39 parts of Chinese Incarvilla Herb, 13 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, stone 11 parts of dry measure used in former times, 15 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, is well mixed immersion：Each raw material is weighed by above-mentioned mass ratio, always Weight is designated as 1 part, adds 8 parts of purified waters, 40-50 DEG C of immersion 2h medicinal material is fully expanded；

Preparation method two

Step one, by 15 parts of fructus ulmi, 17 parts of palas, 15 parts of fruit of Rangoon creeper's shell, 11 parts of Sargent gloryvine, 10 parts of dark plum, 7 parts of black pepper, 16 parts of waxgourd peel, 15 parts of stir-baked SEMEN EURYALES, 12 parts of nutmeg, sweet 12 parts of Radix Astragali (processed), 39 parts of Chinese Incarvilla Herb, 13 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 11 parts of the stem of noble dendrobium, honey 15 parts of honey-fried licorice root, every part of active compound quality is one gram, stirring, mixing in input mixer；Send in pulverizer and crush；

Preparation method three

Step one：By 15 parts of fructus ulmi, 17 parts of palas, 15 parts of fruit of Rangoon creeper's shell, 11 parts of Sargent gloryvine, 10 parts of dark plum, 7 parts of black pepper, 16 parts of waxgourd peel, 15 parts of stir-baked SEMEN EURYALES, 12 parts of nutmeg, sweet 12 parts of Radix Astragali (processed), 39 parts of Chinese Incarvilla Herb, 13 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 11 parts of the stem of noble dendrobium, honey 15 parts of honey-fried licorice root, is well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, decocts 3 little When, add water for the second time 6 times of weight, decocts 2 hours；

Preferred embodiment 6

The Chinese medicine composition of the treatment sheep haemonchiasis of present embodiment, is constituted by following weight portion：17 parts of fructus ulmi, purple 19 parts of riveting, 17 parts of fruit of Rangoon creeper's shell, 13 parts of Sargent gloryvine, 12 parts of dark plum, 9 parts of black pepper, 18 parts of waxgourd peel, 17 parts of stir-baked SEMEN EURYALES, nutmeg 14 parts, sweet 13 parts of Radix Astragali (processed), 42 parts of Chinese Incarvilla Herb, 15 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 12 parts of the stem of noble dendrobium, 16 parts of Radix Glycyrrhizae (processed with honey).

Preparation method one

Step one, mixing immersion：By 17 parts of fructus ulmi, 19 parts of palas, 17 parts of fruit of Rangoon creeper's shell, 13 parts of Sargent gloryvine, 12 parts of dark plum, black 9 parts of pepper, 18 parts of waxgourd peel, 17 parts of stir-baked SEMEN EURYALES, 14 parts of nutmeg, sweet 13 parts of Radix Astragali (processed), 42 parts of Chinese Incarvilla Herb, 15 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, stone 12 parts of dry measure used in former times, 16 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, is well mixed immersion：Each raw material is weighed by above-mentioned mass ratio, always Weight is designated as 1 part, adds 8 parts of purified waters, 40-50 DEG C of immersion 2h medicinal material is fully expanded；

Preparation method two

Step one, by 17 parts of fructus ulmi, 19 parts of palas, 17 parts of fruit of Rangoon creeper's shell, 13 parts of Sargent gloryvine, 12 parts of dark plum, 9 parts of black pepper, 18 parts of waxgourd peel, 17 parts of stir-baked SEMEN EURYALES, 14 parts of nutmeg, sweet 13 parts of Radix Astragali (processed), 42 parts of Chinese Incarvilla Herb, 15 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 12 parts of the stem of noble dendrobium, honey 16 parts of honey-fried licorice root, every part of active compound quality is one gram, stirring, mixing in input mixer；Send in pulverizer and crush；

Preparation method three

Step one：By 17 parts of fructus ulmi, 19 parts of palas, 17 parts of fruit of Rangoon creeper's shell, 13 parts of Sargent gloryvine, 12 parts of dark plum, 9 parts of black pepper, 18 parts of waxgourd peel, 17 parts of stir-baked SEMEN EURYALES, 14 parts of nutmeg, sweet 13 parts of Radix Astragali (processed), 42 parts of Chinese Incarvilla Herb, 15 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 12 parts of the stem of noble dendrobium, honey 16 parts of honey-fried licorice root, is well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, decocts 3 little When, add water for the second time 6 times of weight, decocts 2 hours；

Preferred embodiment 7

The Chinese medicine composition of the treatment sheep haemonchiasis of present embodiment, is constituted by following weight portion：19 parts of fructus ulmi, purple 20 parts of riveting, 19 parts of fruit of Rangoon creeper's shell, 15 parts of Sargent gloryvine, 14 parts of dark plum, 10 parts of black pepper, 20 parts of waxgourd peel, 19 parts of stir-baked SEMEN EURYALES, nutmeg 16 parts, sweet 15 parts of Radix Astragali (processed), 45 parts of Chinese Incarvilla Herb, 16 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 14 parts of the stem of noble dendrobium, 18 parts of Radix Glycyrrhizae (processed with honey).

Preparation method one

Step one, mixing immersion：By 19 parts of fructus ulmi, 20 parts of palas, 19 parts of fruit of Rangoon creeper's shell, 15 parts of Sargent gloryvine, 14 parts of dark plum, black 10 parts of pepper, 20 parts of waxgourd peel, 19 parts of stir-baked SEMEN EURYALES, 16 parts of nutmeg, sweet 15 parts of Radix Astragali (processed), 45 parts of Chinese Incarvilla Herb, 16 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, stone 14 parts of dry measure used in former times, 18 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, is well mixed immersion：Each raw material is weighed by above-mentioned mass ratio, always Weight is designated as 1 part, adds 8 parts of purified waters, 40-50 DEG C of immersion 2h medicinal material is fully expanded；

Preparation method two

Step one, by 19 parts of fructus ulmi, 20 parts of palas, 19 parts of fruit of Rangoon creeper's shell, 15 parts of Sargent gloryvine, 14 parts of dark plum, 10 parts of black pepper, 20 parts of waxgourd peel, 19 parts of stir-baked SEMEN EURYALES, 16 parts of nutmeg, sweet 15 parts of Radix Astragali (processed), 45 parts of Chinese Incarvilla Herb, 16 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 14 parts of the stem of noble dendrobium, honey 18 parts of honey-fried licorice root, every part of active compound quality is one gram, stirring, mixing in input mixer；Send in pulverizer and crush；

Preparation method three

Step one：By 19 parts of fructus ulmi, 20 parts of palas, 19 parts of fruit of Rangoon creeper's shell, 15 parts of Sargent gloryvine, 14 parts of dark plum, 10 parts of black pepper, 20 parts of waxgourd peel, 19 parts of stir-baked SEMEN EURYALES, 16 parts of nutmeg, sweet 15 parts of Radix Astragali (processed), 45 parts of Chinese Incarvilla Herb, 16 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 14 parts of the stem of noble dendrobium, honey 18 parts of honey-fried licorice root, is well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, decocts 3 little When, add water for the second time 6 times of weight, decocts 2 hours；

Preferred embodiment 8

The Chinese medicine composition of the treatment sheep haemonchiasis of present embodiment, is constituted by following weight portion：21 parts of fructus ulmi, purple 22 parts of riveting, 21 parts of fruit of Rangoon creeper's shell, 18 parts of Sargent gloryvine, 16 parts of dark plum, 11 parts of black pepper, 22 parts of waxgourd peel, 21 parts of stir-baked SEMEN EURYALES, nutmeg 18 parts, sweet 16 parts of Radix Astragali (processed), 47 parts of Chinese Incarvilla Herb, 17 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 15 parts of the stem of noble dendrobium, 20 parts of Radix Glycyrrhizae (processed with honey).

Preparation method one

Step one, mixing immersion：By 21 parts of fructus ulmi, 22 parts of palas, 21 parts of fruit of Rangoon creeper's shell, 18 parts of Sargent gloryvine, 16 parts of dark plum, black 11 parts of pepper, 22 parts of waxgourd peel, 21 parts of stir-baked SEMEN EURYALES, 18 parts of nutmeg, sweet 16 parts of Radix Astragali (processed), 47 parts of Chinese Incarvilla Herb, 17 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, stone 15 parts of dry measure used in former times, 20 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, is well mixed immersion：Each raw material is weighed by above-mentioned mass ratio, always Weight is designated as 1 part, adds 8 parts of purified waters, 40-50 DEG C of immersion 2h medicinal material is fully expanded；

Preparation method two

Step one, by 21 parts of fructus ulmi, 22 parts of palas, 21 parts of fruit of Rangoon creeper's shell, 18 parts of Sargent gloryvine, 16 parts of dark plum, 11 parts of black pepper, 22 parts of waxgourd peel, 21 parts of stir-baked SEMEN EURYALES, 18 parts of nutmeg, sweet 16 parts of Radix Astragali (processed), 47 parts of Chinese Incarvilla Herb, 17 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 15 parts of the stem of noble dendrobium, honey 20 parts of honey-fried licorice root, every part of active compound quality is one gram, stirring, mixing in input mixer；Send in pulverizer and crush；

Preparation method three

Step one：By 21 parts of fructus ulmi, 22 parts of palas, 21 parts of fruit of Rangoon creeper's shell, 18 parts of Sargent gloryvine, 16 parts of dark plum, 11 parts of black pepper, 22 parts of waxgourd peel, 21 parts of stir-baked SEMEN EURYALES, 18 parts of nutmeg, sweet 16 parts of Radix Astragali (processed), 47 parts of Chinese Incarvilla Herb, 17 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 15 parts of the stem of noble dendrobium, honey 20 parts of honey-fried licorice root, is well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, decocts 3 little When, add water for the second time 6 times of weight, decocts 2 hours；

Preferred embodiment 9

The Chinese medicine composition of the treatment sheep haemonchiasis of present embodiment, is constituted by following weight portion：23 parts of fructus ulmi, purple 24 parts of riveting, 23 parts of fruit of Rangoon creeper's shell, 19 parts of Sargent gloryvine, 18 parts of dark plum, 12 parts of black pepper, 24 parts of waxgourd peel, 23 parts of stir-baked SEMEN EURYALES, nutmeg 19 parts, sweet 17 parts of Radix Astragali (processed), 48 parts of Chinese Incarvilla Herb, 18 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 17 parts of the stem of noble dendrobium, 23 parts of Radix Glycyrrhizae (processed with honey).

Preparation method one

Step one, mixing immersion：By 23 parts of fructus ulmi, 24 parts of palas, 23 parts of fruit of Rangoon creeper's shell, 19 parts of Sargent gloryvine, 18 parts of dark plum, black 12 parts of pepper, 24 parts of waxgourd peel, 23 parts of stir-baked SEMEN EURYALES, 19 parts of nutmeg, sweet 17 parts of Radix Astragali (processed), 48 parts of Chinese Incarvilla Herb, 18 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, stone 17 parts of dry measure used in former times, 23 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, is well mixed immersion：Each raw material is weighed by above-mentioned mass ratio, always Weight is designated as 1 part, adds 8 parts of purified waters, 40-50 DEG C of immersion 2h medicinal material is fully expanded；

Preparation method two

Step one, by 23 parts of fructus ulmi, 24 parts of palas, 23 parts of fruit of Rangoon creeper's shell, 19 parts of Sargent gloryvine, 18 parts of dark plum, 12 parts of black pepper, 24 parts of waxgourd peel, 23 parts of stir-baked SEMEN EURYALES, 19 parts of nutmeg, sweet 17 parts of Radix Astragali (processed), 48 parts of Chinese Incarvilla Herb, 18 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 17 parts of the stem of noble dendrobium, honey 23 parts of honey-fried licorice root, every part of active compound quality is one gram, stirring, mixing in input mixer；Send in pulverizer and crush；

Preparation method three

Step one：By 23 parts of fructus ulmi, 24 parts of palas, 23 parts of fruit of Rangoon creeper's shell, 19 parts of Sargent gloryvine, 18 parts of dark plum, 12 parts of black pepper, 24 parts of waxgourd peel, 23 parts of stir-baked SEMEN EURYALES, 19 parts of nutmeg, sweet 17 parts of Radix Astragali (processed), 48 parts of Chinese Incarvilla Herb, 18 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 17 parts of the stem of noble dendrobium, honey 23 parts of honey-fried licorice root, is well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, decocts 3 little When, add water for the second time 6 times of weight, decocts 2 hours；

Concrete test

Experimental animal：Clinical haemonchiasis sheep 3, Jing water washing and precipitating methods ovoscopy confirms to carry twisted mawworm, Jing EPG inspections Ovum method confirms that worm's ovum infection rate is close, with comparativity；Three groups, one per group are randomly divided into, different tests are carried out respectively.

Trial drug：This composition group：From oral liquid prepared by preferred embodiment 2, take orally：It is each by sheep body weight 3ml/kg dosage, by gavaging administration, once a day, is used in conjunction 5 days.Control group：Metrifonate pulvis (commercially available prod), takes orally：By disease Sheep body weight 0.1g/kg dosage, by gavaging administration, once a day, is used in conjunction 5 days.Blank control group：Observed drug group is not used, is examined Look into gastrointestinal nematode parasites egg counts in excrement.

Result of the test：

This composition test group, every gram of excrement averagely detects worm's ovum 59 before test sheep medication, after medication 48 hours, excrement Worm's ovum is rechecked, and worm's ovum is 7, and Redution of eggs is 88.1%；After medication 72 hours, faecal egg is rechecked, and worm's ovum is 2, worm's ovum Slip is 8.5%, and excrement always subtracts worm's ovum rate 96.6% after medication 72 hours.

Metrifonate control group, every gram of excrement averagely detects worm's ovum 56 before sheep medication, and after medication 48 hours, faecal egg is multiple Inspection, worm's ovum is 21, Redution of eggs 62.5%；Faecal egg is rechecked after medication 72 hours, and worm's ovum is 6, Redution of eggs 26.7%, excrement always subtracts worm's ovum rate 89.2% after medication 72 hours.

Blank control group observes twisted mawworm egg counts in natural environment in rising not use observed drug group, Worm's ovum 60 is detected before control in every gram of excrement of sick sheep；Worm's ovum 66 in every gram of excrement after 48 hours, worm's ovum increases by 6；72 Worm's ovum 68 in every gram of excrement after hour, worm's ovum increased 2, blank control group after 72 hours every gram of excrement increased 8 worms Ovum.

Curative effect determinate standard：Criterion of cure：Stomachache disappears, and diarrhoea stops, and gathers sick sheep excrement saturated saline floatation Worm's ovum is checked, worm's ovum is not detected.Effective standard：Stomachache disappears, and diarrhoea number of times is reduced 1-2 time daily, and collection sick sheep excrement uses full With saline floatation method inspection, a small amount of worm's ovum is detected.Null criterion：Not up to above-mentioned mark, collection sick sheep excrement is floated with saturated brine Float glass process inspection, detects a large amount of worm's ovums.

Test case：The poultry raiser of certain cultivation company sees a doctor, and claims 6 sheep raised illness occur, follows live diagnosis and treatment sheep Twisted mawworm 6.

Clinical examination and diagnosis：Between sick sheep body temperature is slightly lower 39.2-39.7 DEG C, conjunctiva is pale, and anorexia is weak to disappear Thin, row's black loose stools, inquiry poultry raiser sick sheep is raised situation, parasitosis is posted for interior with reference to the tentative diagnosis of local epidemic disease history, is Further make a definite diagnosis collection sick sheep excrement and send laboratory inspection, with saturated saline floatation worm's ovum is checked, detect twisted mawworm worm's ovum, It is diagnosed as sheep haemonchiasis.

Treatment：The oral liquid prepared with this preferred embodiment 2, all 6 sick sheeps, by body weight 3ml/kg dosage, are led to Cross and gavage administration, once a day, be used in conjunction 5 days；All medication sick sheeps are concentrated on into a colony house and concentrates raising, colony house ground is clear Sweep clean in case collecting sick sheep excrement after medicine；After sick sheep medication 48 hours, the excrement arranged after 6 sick sheep medicines is collected, using full Poly- method is floated with salt solution, twisted mawworm polypide about 630 is detected；Medication collects the excrement arranged after 6 sick sheep medicines after 3 days, still adopts Brine flotation inspection result is used, polypide significantly reduces in excrement, the rear sick sheep diarrhoea of medication 6 days or so stops, and excrement becomes Dilute soft discoid, sick sheep searches for food amount of drinking water compared with showed increased before medicine；Take sick sheep excrement within 15th day to be checked with saturated saline floatation Polypide, does not detect parasitic polypide.

Claims

1. a kind of Chinese medicine composition for treating sheep haemonchiasis, it is characterised in that constitute by following weight portion：Fructus ulmi 10-25 Part, palas 12-25 parts, fruit of Rangoon creeper's shell 10-24 parts, Sargent gloryvine 6-20 parts, dark plum 5-20 parts, black pepper 3-12 parts, waxgourd peel 10-25 Part, stir-baked SEMEN EURYALES 9-25 parts, nutmeg 6-20 parts, sweet Radix Astragali (processed) 6-18 parts, Chinese Incarvilla Herb 30-50 parts, stir-baked RHIZOMA POLYGONATI with yellow rice wine 8-20 parts, stem of noble dendrobium 6-18 Part, Radix Glycyrrhizae (processed with honey) 10-25 parts.

2. the Chinese medicine composition of sheep haemonchiasis is treated according to claim 1, it is characterised in that by following weight portion group Into：10 parts of fructus ulmi, 12 parts of palas, 10 parts of fruit of Rangoon creeper's shell, 6 parts of Sargent gloryvine, 5 parts of dark plum, 3 parts of black pepper, 10 parts of waxgourd peel, stir-baked SEMEN EURYALES 9 parts, 6 parts of nutmeg, sweet 6 parts of Radix Astragali (processed), 30 parts of Chinese Incarvilla Herb, 8 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 6 parts of the stem of noble dendrobium, 10 parts of Radix Glycyrrhizae (processed with honey).

3. the Chinese medicine composition of sheep haemonchiasis is treated according to claim 1, it is characterised in that by following weight portion group Into：25 parts of fructus ulmi, 25 parts of palas, 24 parts of fruit of Rangoon creeper's shell, 20 parts of Sargent gloryvine, 20 parts of dark plum, 12 parts of black pepper, 25 parts of waxgourd peel, stir-fry 25 parts of Gorgon fruit, 20 parts of nutmeg, sweet 18 parts of Radix Astragali (processed), 50 parts of Chinese Incarvilla Herb, 20 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 18 parts of the stem of noble dendrobium, 25 parts of Radix Glycyrrhizae (processed with honey).

4. the Chinese medicine composition of sheep haemonchiasis is treated according to claim 1, it is characterised in that by following weight portion group Into：12 parts of fructus ulmi, 13 parts of palas, 12 parts of fruit of Rangoon creeper's shell, 8 parts of Sargent gloryvine, 7 parts of dark plum, 5 parts of black pepper, 12 parts of waxgourd peel, stir-baked SEMEN EURYALES 11 parts, 8 parts of nutmeg, sweet 9 parts of Radix Astragali (processed), 32 parts of Chinese Incarvilla Herb, 10 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 7 parts of the stem of noble dendrobium, 12 parts of Radix Glycyrrhizae (processed with honey).

5. the Chinese medicine composition of sheep haemonchiasis is treated according to claim 1, it is characterised in that by following weight portion group Into：14 parts of fructus ulmi, 15 parts of palas, 13 parts of fruit of Rangoon creeper's shell, 9 parts of Sargent gloryvine, 8 parts of dark plum, 6 parts of black pepper, 14 parts of waxgourd peel, stir-baked SEMEN EURYALES 13 parts, 10 parts of nutmeg, sweet 11 parts of Radix Astragali (processed), 35 parts of Chinese Incarvilla Herb, 11 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 9 parts of the stem of noble dendrobium, 13 parts of Radix Glycyrrhizae (processed with honey).

6. the Chinese medicine composition of sheep haemonchiasis is treated according to claim 1, it is characterised in that by following weight portion group Into：15 parts of fructus ulmi, 17 parts of palas, 15 parts of fruit of Rangoon creeper's shell, 11 parts of Sargent gloryvine, 10 parts of dark plum, 7 parts of black pepper, 16 parts of waxgourd peel, stir-fry Gorgon euryale Real 15 parts, 12 parts of nutmeg, sweet 12 parts of Radix Astragali (processed), 39 parts of Chinese Incarvilla Herb, 13 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 11 parts of the stem of noble dendrobium, 15 parts of Radix Glycyrrhizae (processed with honey).

7. the Chinese medicine composition of sheep haemonchiasis is treated according to claim 1, it is characterised in that by following weight portion group Into：17 parts of fructus ulmi, 19 parts of palas, 17 parts of fruit of Rangoon creeper's shell, 13 parts of Sargent gloryvine, 12 parts of dark plum, 9 parts of black pepper, 18 parts of waxgourd peel, stir-fry Gorgon euryale Real 17 parts, 14 parts of nutmeg, sweet 13 parts of Radix Astragali (processed), 42 parts of Chinese Incarvilla Herb, 15 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 12 parts of the stem of noble dendrobium, 16 parts of Radix Glycyrrhizae (processed with honey).

8. the Chinese medicine composition of sheep haemonchiasis is treated according to claim 1, it is characterised in that by following weight portion group Into：19 parts of fructus ulmi, 20 parts of palas, 19 parts of fruit of Rangoon creeper's shell, 15 parts of Sargent gloryvine, 14 parts of dark plum, 10 parts of black pepper, 20 parts of waxgourd peel, stir-fry 19 parts of Gorgon fruit, 16 parts of nutmeg, sweet 15 parts of Radix Astragali (processed), 45 parts of Chinese Incarvilla Herb, 16 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 14 parts of the stem of noble dendrobium, 18 parts of Radix Glycyrrhizae (processed with honey).

9. the Chinese medicine composition of sheep haemonchiasis is treated according to claim 1, it is characterised in that by following weight portion group Into：21 parts of fructus ulmi, 22 parts of palas, 21 parts of fruit of Rangoon creeper's shell, 18 parts of Sargent gloryvine, 16 parts of dark plum, 11 parts of black pepper, 22 parts of waxgourd peel, stir-fry 21 parts of Gorgon fruit, 18 parts of nutmeg, sweet 16 parts of Radix Astragali (processed), 47 parts of Chinese Incarvilla Herb, 17 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 15 parts of the stem of noble dendrobium, 20 parts of Radix Glycyrrhizae (processed with honey).

10. the Chinese medicine composition of sheep haemonchiasis is treated according to claim 1, it is characterised in that by following weight portion Composition：23 parts of fructus ulmi, 24 parts of palas, 23 parts of fruit of Rangoon creeper's shell, 19 parts of Sargent gloryvine, 18 parts of dark plum, 12 parts of black pepper, 24 parts of waxgourd peel, 23 parts of stir-baked SEMEN EURYALES, 19 parts of nutmeg, sweet 17 parts of Radix Astragali (processed), 48 parts of Chinese Incarvilla Herb, 18 parts of stir-baked RHIZOMA POLYGONATI with yellow rice wine, 17 parts of the stem of noble dendrobium, 23 parts of Radix Glycyrrhizae (processed with honey).