CN106619705A - Soft capsules containing calcium, magnesium and vitamin D and preparation method of soft capsules - Google Patents
Soft capsules containing calcium, magnesium and vitamin D and preparation method of soft capsules Download PDFInfo
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- CN106619705A CN106619705A CN201611095087.0A CN201611095087A CN106619705A CN 106619705 A CN106619705 A CN 106619705A CN 201611095087 A CN201611095087 A CN 201611095087A CN 106619705 A CN106619705 A CN 106619705A
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- gram
- calcium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
Abstract
The invention discloses soft capsules containing calcium, magnesium and vitamin D and a preparation method of the soft capsules, and belongs to the technical field of health products. In order to provide stable and content-controllable sources of calcium, magnesium and vitamin D for people, 1000 grains of the soft capsules containing calcium, magnesium and vitamin D comprises the following substances: 420-425g of calcium carbonate, 290-295g of magnesium carbonate, 0.8g of vitamin D3, 360-370g of soybean oil, 68.4-70g of beeswax, 271-295g of gelatin, 101.28-110g of glycerol, 268-288g of purified water, and 0.21-0.23g of titanium dioxide, thereby providing stable and content-controllable sources of calcium, magnesium and vitamin D for the people. Prevention focuses more on diseases caused by deficiency of calcium, magnesium and vitamin D, and enhancement of physical quality of the people.
Description
Technical field
The invention belongs to health product technology field, and in particular to a kind of calcium and magnesium adds vitamin D soft capsule and preparation method thereof.
Background technology
Calcium is element necessary to biology.For human body, no matter in muscle, nerve, body fluid and bone, all useful Ca2+Knot
The protein of conjunction.Calcium is the main inorganic composition of mankind's bone, tooth, is also that neurotransmission, contraction of muscle, blood clotting, hormone are released
Put and the necessary element such as galactosis.Calcium accounts for the 1.4% of body mass, participates in metabolism, and calcium is must be supplemented with daily；
Calcium content is not enough or surplus all can affect to grow and health in human body.The daily supply standard of recommendation of calcium is as follows：From first
It is raw to 10 years old 600 milligrams of children, 10～13 years old 800 milligrams, 13～16 years old 1200 milligrams, 16～l9 year 1000 milligrams, grow up man
800 milligrams of female, 1500 milligrams of pregnant woman, 2000 milligrams of wet nurse.Prepubertal children grows rapidly, and the requirement of calcium is also relative
Maximum, up to 2～4 times of adult's requirement.Pay special attention to supplement.If calcium insufficiency of intake, human body just occurs physiological
Calcium is overdrawed, and causes calcium level to decline.When calcium level drops to certain threshold value, will promote by pth secretion first shape
Parathyrine.Parathormone has broken bone effect, and calcium back suction that will be in bone is recalled, and uses maintenance calcium level.In calcium deficiency
At the initial stage, when calcium deficiency degree is lighter, simply there is invertibity physiological function exception, ventricular premature contraction, mood occurs in such as heart
The reactions such as unstable, sleep quality decline.Lasting low blood calcium, particularly after middle age, human body is chronically at negative calcium balance shape
State, causes pth secretion hyperfunction, and what is stood in the breach is bone, because bone calcium continues to disengage in a large number, cause osteoporosis and
Osteoproliferation.On the other hand, in the case of parathyroid gland is persistently elevated, because parathormone has calcium on cell membrane is promoted
Passage is opened and closes and do not live, and prevents calcium pump, weakens calcium pump function, causes intracellular calcium content to raise.Lasting cell
Interior high calcium, activated cell is hyperfunction as wild horse out of control, uncontrolled, causes cellular energy to exhaust.At the same time, metabolic waste is again
Less than elimination in time, oneself injury will be constituted, cause cell to tend to unusual calcification decline.Due to calcium deficiency, sclerotin is caused to be dredged
The disease such as pine, osteoproliferation, children rachitis, tetany disease and hypertension, kidney stone, colon cancer, senile dementia is sent out
It is raw.
Magnesium is a kind of participation organism normal activities and the requisite element of metabolic processes.Magnesium affects cell
Various biological functions：Affect the transhipment of potassium ion and calcium ion, the transmission of adjustment signal, participate in energetic supersession, protein and
The synthesis of nucleic acid；Can by be complexed negative electrical charge group, especially the phosphate group in nucleotides come play maintain material structure
And function；The activation and suppression of catalyzing enzyme and the regulation and control of cell cycle, cell propagation and cell differentiation；Magnesium also participates in maintaining base
It is and also relevant with body oxidative stress and tumour generation because of the stability organized.Adult male about needs daily 350 milligrams of magnesium, into
Year, women was about 300 milligrams, and pregnant woman and the phase women of breast-feeding are about 450 milligrams, and children are 150 milligrams within 2～3 years old, are within 3～6 years old
200 milligrams.Tolerable highest intake (UL) is set to 700mg/d.Magnesium shortage is clinically mainly shown as mood uneasiness, Yi Ji
Dynamic, tetany, exagger etc., under normal circumstances, due to the adjustment effect of kidney, oral excessive magnesium will not typically occur magnesium
Poisoning.When renal insufficiency, a large amount of oral magnesium can cause magnesium to be poisoned, and show as suffering from abdominal pain, suffer from diarrhoea, vomit, polydipsia, tired nothing
There is expiratory dyspnea, cyanosis, mydriasis etc. in power, severe patient.
Vitamin D deficiency can cause the osteomalacia of juvenile's rickets and adult.Rickets is mainly in infant, main table
It is now the change of neuropsychic symptom and bone.Hidrosis, sleep terror fright at night, irritability are shown as on neuropsychic symptom.The change of bone
The factors such as the degree with age, growth rate and vitamin D deficiency are relevant.May occur in which Lu osteomalacia, beading of ribs etc..Osteomalacia
Disease is multiple to be born in adult, is more common in the women and weak and sickly old man of pregnant fecund.Modal symptom is ostalgia, myasthenia
With bone tenderness.People with osteoporosis can effectively improve the suction of calcium ion by the suitable vitamin D of addition and magnesium
Receipts degree.In addition, vitamin D also be used to reduce the probability of colon cancer, breast cancer and prostate cancer, also have to immune system
Humidification.The mechanism of action of vitamin D.
The content of the invention
In view of calcium, three kinds of elements of magnesium and vitamin D each for human body important function and three promote each other
Effect, i.e., vitamin D and magnesium can effectively improve the trap of calcium ion.The present invention proposes that calcium and magnesium adds vitamin D soft capsule
And preparation method thereof, it is therefore an objective to provide a kind of stable and content controllable calcium, three kinds of elements of magnesium and vitamin D for people
Source.
In order to solve above-mentioned technical problem, the technical solution used in the present invention is：
A kind of calcium and magnesium adds vitamin D soft capsule, it is characterised in that：In terms of adding vitamin D soft capsule by 1000 calcium and magnesiums, comprising
Following material and its 420-425 gram of content calcium carbonate, 290-295 gram of magnesium carbonate, 0.8 gram of vitamine D3, soybean oil 360-370
Gram, 68.4-70 gram of beeswax, 271-285 gram of gelatin, 101.28-110 gram of glycerine, purified water 268-288 gram, titanium dioxide 0.21-
0.23 gram.
In terms of adding vitamin D soft capsule by 1000 calcium and magnesiums, comprising following material and its 423 grams of content calcium carbonate, magnesium carbonate
292 grams, 0.8 gram of vitamine D3,365 grams of soybean oil, 69.2 grams of beeswax, 278 grams of gelatin, 105.64 grams of glycerine, purified water 278
Gram, 0.22 gram of titanium dioxide.
A kind of calcium and magnesium adds the preparation method of vitamin D soft capsule, it is characterised in that：The preparation side comprises the steps,
Step one, magnesium carbonate is crushed, 100 mesh sieves are crossed, and is taken the carbonic acid magnesium powder after sieving and is mixed with vitamine D3
Prepared mixed powder A；
Calcium carbonate crushing, 100 mesh sieves excessively are obtained calcium carbonate fine powder by step 2；
Step 3, the calcium carbonate fine powder weighed in step 2 mixes 30 minutes with mixed powder A, obtains mixture B；
Step 4, weighs soybean oil and gram beeswax mixing, then mixed liquor is heated into 80 degrees Celsius so that beeswax is melted
After be cooled to 30 degrees Celsius, obtain oily wax liquor；
Step 5, oily wax liquor is mixed with mixture B, is then ground 3 times using colloid mill so that oily wax liquor and mixture
B is well mixed, and obtains content feed liquid；
Step 6, is heated to glycerine and purified water 60 degrees Celsius and is subsequently adding gelatin in change glue in-tank mixing, adds bright
80 degrees Celsius are again heated to after glue and 2-3 hours are kept, colloidal sol is obtained；
Step 7, adds titanium dioxide in colloidal sol, then stirs, and will change glue tank and vacuumize will change glue tank inside gas
Voltage-controlled system in -0.08Mpa to -0.06Mpa, to carry out deaeration process, then cross 100 mesh sieves and be incubated 60 degrees Celsius and obtain by colloidal sol
Glue；
Step 8, glue is mixed and by mixed liquid in 18～26 DEG C of temperature, relative humidity with content feed liquid
It is placed into the environment of 45-65% in soft capsule pellet press and suppresses soft capsule；
Step 9, in 18～26 DEG C of temperature, places in the environment of relative humidity 45-65% and is shaped for 4 hours；
Step 10,20～25 DEG C of temperature after sizing are dried when 18-24 is placed in the environment of relative humidity 45-50%；
Step 11, carries out washing ball process with 95% ethanol to dried soft capsule, washes after ball and is dried；
Step 12, is wrapped inside to soft capsule dress, then external packing after drying；
Step 13, randomly selects the inspection of the soft capsule after external packing, after the assay was approved by product warehousing.
Present invention has the advantages that:People provide a kind of stable and content controllable calcium, three kinds of elements of magnesium and vitamin D
Source.Prevention more weight is due to lacking calcium, the caused disease of magnesium and three kinds of element institutes of vitamin D, and the physique for strengthening people.
Specific embodiment
Below by the description to embodiment, the present invention is further detailed explanation, to help people in the art
Member has more complete, accurate and deep understanding to inventive concept of the invention, technical scheme.
Embodiment 1
A kind of calcium and magnesium adds vitamin D soft capsule, add vitamin D soft capsule by 1000 calcium and magnesiums in terms of, comprising following material and
423 grams of its content calcium carbonate, 292 grams of magnesium carbonate, 0.8 gram of vitamine D3,365 grams of soybean oil, 69.2 grams of beeswax, gelatin 278
Gram, 105.64 grams of glycerine, 278 grams of purified water, 0.22 gram of titanium dioxide.
Above-mentioned calcium and magnesium adds the preparation method of vitamin D soft capsule, comprises the steps,
Step one, by magnesium carbonate crush, cross 100 mesh sieves, take 292 grams sieve after carbonic acid magnesium powder with 0.8 gram tie up
Raw element D3 is mixed to prepare mixed powder A；
Calcium carbonate crushing, 100 mesh sieves excessively are obtained calcium carbonate fine powder by step 2；
Step 3,423 grams of the calcium carbonate fine powder weighed in step 2 mixes 30 minutes with mixed powder A, obtains mixture B；
Step 4, weighs 365 grams of soybean oils and 69.2 grams of beeswax mixing, then mixed liquor is heated into 80 degrees Celsius, makes
Obtain and be cooled to 30 degrees Celsius after beeswax melting, obtain oily wax liquor；
Step 5, oily wax liquor is mixed with mixture B, is then ground 3 times using colloid mill so that oily wax liquor and mixture
B is well mixed, and obtains content feed liquid；
105.64 grams of glycerine and 278 grams of purified waters are heated to 60 degrees Celsius and then are added by step 6 in change glue in-tank mixing
Enter 278 grams of gelatin, to add and be again heated to 80 degrees Celsius after gelatin and keep 2-3 hours, obtain colloidal sol；
Step 7, adds 0.22 gram of titanium dioxide in colloidal sol, then stirs, and will change glue tank and vacuumizes and will change glue tank
In -0.08Mpa to -0.06Mpa, to carry out deaeration process, then colloidal sol crosses 100 mesh sieves and to be incubated 60 Celsius for air pressure inside control
Degree obtains glue；
Step 8, glue is mixed and by mixed liquid in 18～26 DEG C of temperature, relative humidity with content feed liquid
It is placed into the environment of 45-65% in soft capsule pellet press and suppresses soft capsule；
Step 9, in 18～26 DEG C of temperature, places in the environment of relative humidity 45-65% and is shaped for 4 hours；
Step 10,20～25 DEG C of temperature after sizing are dried when 18-24 is placed in the environment of relative humidity 45-50%；
Step 11, carries out washing ball process with 95% ethanol to dried soft capsule, washes after ball and is dried；
Step 12, is wrapped inside to soft capsule dress, then external packing after drying；
Step 13, randomly selects the inspection of the soft capsule after external packing, after the assay was approved by product warehousing.
Embodiment 2
A kind of calcium and magnesium adds vitamin D soft capsule, add vitamin D soft capsule by 1000 calcium and magnesiums in terms of, comprising following material and
425 grams of its content calcium carbonate, 290 grams of magnesium carbonate, 0.8 gram of vitamine D3,370 grams of soybean oil, 68.4 grams of beeswax, gelatin 271
Gram, 110 grams of glycerine, 288 grams of purified water, 0.21 gram of titanium dioxide.
Above-mentioned calcium and magnesium adds the preparation method of vitamin D soft capsule, comprises the steps,
Step one, by magnesium carbonate crush, cross 100 mesh sieves, take 290 grams sieve after carbonic acid magnesium powder with 0.8 gram tie up
Raw element D3 is mixed to prepare mixed powder A；
Calcium carbonate crushing, 100 mesh sieves excessively are obtained calcium carbonate fine powder by step 2；
Step 3,425 grams of the calcium carbonate fine powder weighed in step 2 mixes 30 minutes with mixed powder A, obtains mixture B；
Step 4, weighs 370 grams of soybean oils and 68.4 grams of beeswax mixing, then mixed liquor is heated into 80 degrees Celsius, makes
Obtain and be cooled to 30 degrees Celsius after beeswax melting, obtain oily wax liquor；
Step 5, oily wax liquor is mixed with mixture B, is then ground 3 times using colloid mill so that oily wax liquor and mixture
B is well mixed, and obtains content feed liquid；
110 grams of glycerine and 288 grams of purified waters are heated to 60 degrees Celsius and are subsequently adding by step 6 in change glue in-tank mixing
271 grams of gelatin, to add and be again heated to 80 degrees Celsius after gelatin and keep 2-3 hours, obtain colloidal sol；
Step 7, adds 0.21 gram of titanium dioxide in colloidal sol, then stirs, and will change glue tank and vacuumizes and will change glue tank
In -0.08Mpa to -0.06Mpa, to carry out deaeration process, then colloidal sol crosses 100 mesh sieves and to be incubated 60 Celsius for air pressure inside control
Degree obtains glue；
Step 8, glue is mixed and by mixed liquid in 18～26 DEG C of temperature, relative humidity with content feed liquid
It is placed into the environment of 45-65% in soft capsule pellet press and suppresses soft capsule；
Step 9, in 18～26 DEG C of temperature, places in the environment of relative humidity 45-65% and is shaped for 4 hours；
Step 10,20～25 DEG C of temperature after sizing are dried when 18-24 is placed in the environment of relative humidity 45-50%；
Step 11, carries out washing ball process with 95% ethanol to dried soft capsule, washes after ball and is dried；
Step 12, is wrapped inside to soft capsule dress, then external packing after drying；
Step 13, randomly selects the inspection of the soft capsule after external packing, after the assay was approved by product warehousing.
Embodiment 3
A kind of calcium and magnesium adds vitamin D soft capsule, add vitamin D soft capsule by 1000 calcium and magnesiums in terms of, comprising following material and
420 grams of its content calcium carbonate, 295 grams of magnesium carbonate, 0.8 gram of vitamine D3,360 grams of soybean oil, 70 grams of beeswax, 285 grams of gelatin,
101.28 grams of glycerine, 260 grams of purified water, 0.23 gram of titanium dioxide.
Above-mentioned calcium and magnesium adds the preparation method of vitamin D soft capsule, comprises the steps,
Step one, by magnesium carbonate crush, cross 100 mesh sieves, take 295 grams sieve after carbonic acid magnesium powder with 0.8 gram tie up
Raw element D3 is mixed to prepare mixed powder A；
Calcium carbonate crushing, 100 mesh sieves excessively are obtained calcium carbonate fine powder by step 2；
Step 3,420 grams of the calcium carbonate fine powder weighed in step 2 mixes 30 minutes with mixed powder A, obtains mixture B；
Step 4, weighs 360 grams of soybean oils and 70 grams of beeswax mixing, then mixed liquor is heated into 80 degrees Celsius so that
30 degrees Celsius are cooled to after beeswax melting, oily wax liquor is obtained；
Step 5, oily wax liquor is mixed with mixture B, is then ground 3 times using colloid mill so that oily wax liquor and mixture
B is well mixed, and obtains content feed liquid；
101.28 grams of glycerine and 260 grams of purified waters are heated to 60 degrees Celsius and then are added by step 6 in change glue in-tank mixing
Enter 285 grams of gelatin, to add and be again heated to 80 degrees Celsius after gelatin and keep 2-3 hours, obtain colloidal sol；
Step 7, adds 0.23 gram of titanium dioxide in colloidal sol, then stirs, and will change glue tank and vacuumizes and will change glue tank
In -0.08Mpa to -0.06Mpa, to carry out deaeration process, then colloidal sol crosses 100 mesh sieves and to be incubated 60 Celsius for air pressure inside control
Degree obtains glue；
Step 8, glue is mixed and by mixed liquid in 18～26 DEG C of temperature, relative humidity with content feed liquid
It is placed into the environment of 45-65% in soft capsule pellet press and suppresses soft capsule；
Step 9, in 18～26 DEG C of temperature, places in the environment of relative humidity 45-65% and is shaped for 4 hours；
Step 10,20～25 DEG C of temperature after sizing are dried when 18-24 is placed in the environment of relative humidity 45-50%；
Step 11, carries out washing ball process with 95% ethanol to dried soft capsule, washes after ball and is dried；
Step 12, is wrapped inside to soft capsule dress, then external packing after drying；
Step 13, randomly selects the inspection of the soft capsule after external packing, after the assay was approved by product warehousing.
The present invention is exemplarily described above, it is clear that the present invention is implemented and is not subject to the restrictions described above,
As long as the improvement of the various unsubstantialities that method of the present invention design and technical scheme are carried out is employed, or it is not improved by this
Bright design and technical scheme directly applies to other occasions, within protection scope of the present invention.The protection of the present invention
The protection domain that scope should be limited by claims is defined.
Claims (3)
1. a kind of calcium and magnesium adds vitamin D soft capsule, it is characterised in that：In terms of adding vitamin D soft capsule by 1000 calcium and magnesiums, comprising such as
420-425 gram of lower material and its content calcium carbonate, 290-295 gram of magnesium carbonate, 0.8 gram of vitamine D3,360-370 gram of soybean oil,
68.4-70 gram of beeswax, 271-285 gram of gelatin, 101.28-110 gram of glycerine, purified water 268-288 gram, titanium dioxide 0.21-
0.23 gram.
2. calcium and magnesium according to claim 1 adds vitamin D soft capsule, it is characterised in that：Add vitamin D with 1000 calcium and magnesiums
Soft capsule meter, comprising following material and its 423 grams of content calcium carbonate, 292 grams of magnesium carbonate, 0.8 gram of vitamine D3, soybean oil 365
Gram, 69.2 grams of beeswax, 278 grams of gelatin, 105.64 grams of glycerine, 278 grams of purified water, 0.22 gram of titanium dioxide.
3. a kind of calcium and magnesium adds the preparation method of vitamin D soft capsule, it is characterised in that：The preparation side comprises the steps,
Step one, magnesium carbonate is crushed, 100 mesh sieves are crossed, and is taken the carbonic acid magnesium powder after sieving and is mixed to prepare with vitamine D3
Mixed powder A；
Calcium carbonate crushing, 100 mesh sieves excessively are obtained calcium carbonate fine powder by step 2；
Step 3, the calcium carbonate fine powder weighed in step 2 mixes 30 minutes with mixed powder A, obtains mixture B；
Step 4, weighs soybean oil and gram beeswax mixing, then mixed liquor is heated into 80 degrees Celsius so that drop after beeswax melting
Temperature obtains oily wax liquor to 30 degrees Celsius；
Step 5, oily wax liquor is mixed with mixture B, is then ground 3 times using colloid mill so that oily wax liquor is mixed with mixture B
Close uniform, obtain content feed liquid；
Step 6, is heated to glycerine and purified water 60 degrees Celsius and is subsequently adding gelatin, after adding gelatin in change glue in-tank mixing
It is again heated to 80 degrees Celsius and keeps 2-3 hours, obtains colloidal sol；
Step 7, adds titanium dioxide in colloidal sol, then stirs, and will change glue tank and vacuumizes and will change glue tank air pressure inside control
System in -0.08Mpa to -0.06Mpa, to carry out deaeration process, then cross 100 mesh sieves and be incubated 60 degrees Celsius and obtain glue by colloidal sol
Liquid；
Step 8, glue is mixed and by mixed liquid in 18～26 DEG C of temperature, relative humidity 45- with content feed liquid
It is placed into 65% environment in soft capsule pellet press and suppresses soft capsule；
Step 9, in 18～26 DEG C of temperature, places in the environment of relative humidity 45-65% and is shaped for 4 hours；
Step 10,20～25 DEG C of temperature after sizing are dried when 18-24 is placed in the environment of relative humidity 45-50%；
Step 11, carries out washing ball process with 95% ethanol to dried soft capsule, washes after ball and is dried；
Step 12, is wrapped inside to soft capsule dress, then external packing after drying；
Step 13, randomly selects the inspection of the soft capsule after external packing, after the assay was approved by product warehousing.
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| CN201611095087.0A CN106619705A (en) | 2016-12-02 | 2016-12-02 | Soft capsules containing calcium, magnesium and vitamin D and preparation method of soft capsules |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108065403A (en) * | 2017-12-08 | 2018-05-25 | 芜湖市诺康生物科技有限公司 | A kind of calcium and magnesium adds the preparation method of dimension D soft capsules |
| CN108936687A (en) * | 2018-08-08 | 2018-12-07 | 深圳极醇健康产业股份有限公司 | A kind of soft capsule and preparation method thereof of replenishing vitamins KD calcium |
| CN113244260A (en) * | 2021-04-15 | 2021-08-13 | 山东卫康生物医药科技有限公司 | Soft capsule for supplementing calcium, magnesium and vitamin D |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1686182A (en) * | 2005-03-21 | 2005-10-26 | 成刚 | Medicinal preparation for supplementing calcium, magnesium and vitamin D |
| CN101647810A (en) * | 2009-09-04 | 2010-02-17 | 芜湖市诺康生物科技有限公司 | Liquid calcium soft capsule |
| CN102125581A (en) * | 2010-01-14 | 2011-07-20 | 哈尔滨顺亿堂医药生物科技开发有限公司 | Method for preparing vitamin D calcium soft capsules |
| CN105963318A (en) * | 2016-05-03 | 2016-09-28 | 宣城柏维力生物工程有限公司 | Calcium-magnesium-vitamin D tablets and preparation method thereof |
-
2016
- 2016-12-02 CN CN201611095087.0A patent/CN106619705A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1686182A (en) * | 2005-03-21 | 2005-10-26 | 成刚 | Medicinal preparation for supplementing calcium, magnesium and vitamin D |
| CN101647810A (en) * | 2009-09-04 | 2010-02-17 | 芜湖市诺康生物科技有限公司 | Liquid calcium soft capsule |
| CN102125581A (en) * | 2010-01-14 | 2011-07-20 | 哈尔滨顺亿堂医药生物科技开发有限公司 | Method for preparing vitamin D calcium soft capsules |
| CN105963318A (en) * | 2016-05-03 | 2016-09-28 | 宣城柏维力生物工程有限公司 | Calcium-magnesium-vitamin D tablets and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 郭建生等: "《保健品与亚健康》", 31 May 2009, 中国中医药出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108065403A (en) * | 2017-12-08 | 2018-05-25 | 芜湖市诺康生物科技有限公司 | A kind of calcium and magnesium adds the preparation method of dimension D soft capsules |
| CN108936687A (en) * | 2018-08-08 | 2018-12-07 | 深圳极醇健康产业股份有限公司 | A kind of soft capsule and preparation method thereof of replenishing vitamins KD calcium |
| CN113244260A (en) * | 2021-04-15 | 2021-08-13 | 山东卫康生物医药科技有限公司 | Soft capsule for supplementing calcium, magnesium and vitamin D |
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