CN106591172A - 一种赤红球菌pta-2及其固定化和应用 - Google Patents
一种赤红球菌pta-2及其固定化和应用 Download PDFInfo
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- CN106591172A CN106591172A CN201610204843.2A CN201610204843A CN106591172A CN 106591172 A CN106591172 A CN 106591172A CN 201610204843 A CN201610204843 A CN 201610204843A CN 106591172 A CN106591172 A CN 106591172A
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- Prior art keywords
- pta
- rhodococcus ruber
- methyl benzenesulfonic
- benzenesulfonic acid
- toluenesulfonic acid
- Prior art date
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- 241000187563 Rhodococcus ruber Species 0.000 title claims abstract description 29
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- 239000000243 solution Substances 0.000 description 14
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- 229910052921 ammonium sulfate Inorganic materials 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 5
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- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- 238000001994 activation Methods 0.000 description 3
- 239000007900 aqueous suspension Substances 0.000 description 3
- 239000001110 calcium chloride Substances 0.000 description 3
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- 239000001888 Peptone Substances 0.000 description 2
- 108010080698 Peptones Proteins 0.000 description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 2
- 230000002308 calcification Effects 0.000 description 2
- 235000010410 calcium alginate Nutrition 0.000 description 2
- 239000000648 calcium alginate Substances 0.000 description 2
- 229960002681 calcium alginate Drugs 0.000 description 2
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 description 2
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- QGLVWTFUWVTDEQ-UHFFFAOYSA-N 2-chloro-3-methoxyphenol Chemical compound COC1=CC=CC(O)=C1Cl QGLVWTFUWVTDEQ-UHFFFAOYSA-N 0.000 description 1
- CQPFMGBJSMSXLP-ZAGWXBKKSA-M Acid orange 7 Chemical compound OC1=C(C2=CC=CC=C2C=C1)/N=N/C1=CC=C(C=C1)S(=O)(=O)[O-].[Na+] CQPFMGBJSMSXLP-ZAGWXBKKSA-M 0.000 description 1
- PLXMOAALOJOTIY-FPTXNFDTSA-N Aesculin Natural products OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1Oc2cc3C=CC(=O)Oc3cc2O PLXMOAALOJOTIY-FPTXNFDTSA-N 0.000 description 1
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- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 229930195503 Fortimicin Natural products 0.000 description 1
- CMWTZPSULFXXJA-UHFFFAOYSA-N Naproxen Natural products C1=C(C(C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-UHFFFAOYSA-N 0.000 description 1
- VONGZNXBKCOUHB-UHFFFAOYSA-N Phenylmethyl butanoate Chemical compound CCCC(=O)OCC1=CC=CC=C1 VONGZNXBKCOUHB-UHFFFAOYSA-N 0.000 description 1
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- BIDUPMYXGFNAEJ-APGVDKLISA-N astromicin Chemical compound O[C@@H]1[C@H](N(C)C(=O)CN)[C@@H](OC)[C@@H](O)[C@H](N)[C@H]1O[C@@H]1[C@H](N)CC[C@@H]([C@H](C)N)O1 BIDUPMYXGFNAEJ-APGVDKLISA-N 0.000 description 1
- 150000001555 benzenes Chemical class 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- -1 casting Substances 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
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- UOAMTSKGCBMZTC-UHFFFAOYSA-N dicofol Chemical compound C=1C=C(Cl)C=CC=1C(C(Cl)(Cl)Cl)(O)C1=CC=C(Cl)C=C1 UOAMTSKGCBMZTC-UHFFFAOYSA-N 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- XHCADAYNFIFUHF-TVKJYDDYSA-N esculin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C(=C1)O)=CC2=C1OC(=O)C=C2 XHCADAYNFIFUHF-TVKJYDDYSA-N 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
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- 239000003317 industrial substance Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 229910017053 inorganic salt Inorganic materials 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
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- 231100001224 moderate toxicity Toxicity 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 description 1
- 229960002009 naproxen Drugs 0.000 description 1
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- 125000000542 sulfonic acid group Chemical group 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F3/00—Biological treatment of water, waste water, or sewage
- C02F3/34—Biological treatment of water, waste water, or sewage characterised by the microorganisms used
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/14—Enzymes or microbial cells immobilised on or in an inorganic carrier
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2101/00—Nature of the contaminant
- C02F2101/30—Organic compounds
- C02F2101/40—Organic compounds containing sulfur
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Hydrology & Water Resources (AREA)
- Biodiversity & Conservation Biology (AREA)
- Molecular Biology (AREA)
- Environmental & Geological Engineering (AREA)
- Water Supply & Treatment (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
Abstract
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CN201610204843.2A CN106591172B (zh) | 2016-04-01 | 2016-04-01 | 一种赤红球菌pta-2及其固定化和应用 |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020147530A1 (zh) | 2019-01-15 | 2020-07-23 | 辽宁格瑞仕特生物制药有限公司 | 分离的赤红球菌细胞壁骨架在制备治疗人乳头瘤病毒感染的药物中的用途 |
WO2020216281A1 (zh) | 2019-04-24 | 2020-10-29 | 辽宁格瑞仕特生物制药有限公司 | 赤红球菌产品在治疗热损伤中的用途 |
WO2021147899A1 (zh) | 2020-01-21 | 2021-07-29 | 辽宁格瑞仕特生物制药有限公司 | 赤红球菌细胞壁骨架在再生医学中的用途 |
Citations (3)
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CN100371438C (zh) * | 2005-04-27 | 2008-02-27 | 中国石油化工股份有限公司 | 一株用于生物脱硫的红串红球菌及应用 |
CN101475924A (zh) * | 2009-01-12 | 2009-07-08 | 中国科学院武汉病毒研究所 | 一种降解3-硝基甲苯的红球菌菌株及制备方法和应用 |
CN103627653A (zh) * | 2013-10-17 | 2014-03-12 | 浙江省环境保护科学设计研究院 | 一种赤红球菌菌株及其在含有机污染物的废水处理中的应用 |
-
2016
- 2016-04-01 CN CN201610204843.2A patent/CN106591172B/zh active Active
Patent Citations (3)
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CN100371438C (zh) * | 2005-04-27 | 2008-02-27 | 中国石油化工股份有限公司 | 一株用于生物脱硫的红串红球菌及应用 |
CN101475924A (zh) * | 2009-01-12 | 2009-07-08 | 中国科学院武汉病毒研究所 | 一种降解3-硝基甲苯的红球菌菌株及制备方法和应用 |
CN103627653A (zh) * | 2013-10-17 | 2014-03-12 | 浙江省环境保护科学设计研究院 | 一种赤红球菌菌株及其在含有机污染物的废水处理中的应用 |
Non-Patent Citations (2)
Title |
---|
YOSHIKAZU IZUMI ET AL.: "Selective Desulfurization of Dibenzothiophene by Rhodococcus erythropolis D-1", 《APPLIED AND ENVIRONMENTAL MICROBIOLOGY》 * |
沈洁等: "化工厂废水中对甲苯磺酸降解菌的筛选及降解特性研究", 《浙江化工》 * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020147530A1 (zh) | 2019-01-15 | 2020-07-23 | 辽宁格瑞仕特生物制药有限公司 | 分离的赤红球菌细胞壁骨架在制备治疗人乳头瘤病毒感染的药物中的用途 |
WO2020147472A1 (zh) | 2019-01-15 | 2020-07-23 | 辽宁格瑞仕特生物制药有限公司 | 赤红球菌产品及其制药用途 |
CN111727235A (zh) * | 2019-01-15 | 2020-09-29 | 辽宁格瑞仕特生物制药有限公司 | 赤红球菌产品及其制药用途 |
WO2020216281A1 (zh) | 2019-04-24 | 2020-10-29 | 辽宁格瑞仕特生物制药有限公司 | 赤红球菌产品在治疗热损伤中的用途 |
US12064458B2 (en) | 2019-04-24 | 2024-08-20 | Liaoning Greatest Bio-Pharmaceutical Co., Ltd. | Use of Rhodococcus ruber product in treating thermal injury |
WO2021147899A1 (zh) | 2020-01-21 | 2021-07-29 | 辽宁格瑞仕特生物制药有限公司 | 赤红球菌细胞壁骨架在再生医学中的用途 |
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