CN106573018A - 用于治疗骨骼缺损的体干细胞 - Google Patents
用于治疗骨骼缺损的体干细胞 Download PDFInfo
- Publication number
- CN106573018A CN106573018A CN201580043614.0A CN201580043614A CN106573018A CN 106573018 A CN106573018 A CN 106573018A CN 201580043614 A CN201580043614 A CN 201580043614A CN 106573018 A CN106573018 A CN 106573018A
- Authority
- CN
- China
- Prior art keywords
- cells
- sample
- somatic stem
- stem cell
- lgr5
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Gynecology & Obstetrics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110799982.5A CN113521107A (zh) | 2014-11-19 | 2015-11-18 | 用于治疗骨骼缺损的体干细胞 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462081880P | 2014-11-19 | 2014-11-19 | |
| US62/081,880 | 2014-11-19 | ||
| PCT/US2015/061257 WO2016081553A1 (en) | 2014-11-19 | 2015-11-18 | Somatic stem cells for treating bone defects |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110799982.5A Division CN113521107A (zh) | 2014-11-19 | 2015-11-18 | 用于治疗骨骼缺损的体干细胞 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106573018A true CN106573018A (zh) | 2017-04-19 |
Family
ID=55960744
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580043614.0A Pending CN106573018A (zh) | 2014-11-19 | 2015-11-18 | 用于治疗骨骼缺损的体干细胞 |
| CN202110799982.5A Pending CN113521107A (zh) | 2014-11-19 | 2015-11-18 | 用于治疗骨骼缺损的体干细胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110799982.5A Pending CN113521107A (zh) | 2014-11-19 | 2015-11-18 | 用于治疗骨骼缺损的体干细胞 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20160136203A1 (enExample) |
| EP (1) | EP3220929A4 (enExample) |
| JP (1) | JP2018501189A (enExample) |
| CN (2) | CN106573018A (enExample) |
| HK (1) | HK1232131A1 (enExample) |
| TW (2) | TW201625280A (enExample) |
| WO (1) | WO2016081553A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201819623A (zh) * | 2016-10-18 | 2018-06-01 | 美商幹細胞生物科技股份有限公司 | 用於降低膽紅素位準之組成物及方法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010056341A2 (en) * | 2008-11-12 | 2010-05-20 | The University Of Vermont And State Agriculture College | Compositions and methods for tissue repair |
| CN103097519A (zh) * | 2010-08-04 | 2013-05-08 | 干细胞生物科技公司 | 体干细胞 |
| US20140161774A1 (en) * | 2012-12-06 | 2014-06-12 | StemBios Technologies, Inc. | Lgr5+ SOMATIC STEM CELLS |
| US20140219952A1 (en) * | 2010-03-23 | 2014-08-07 | The Johns Hopkins University | Methods of treatment using stem cell mobilizers |
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| JP2936171B2 (ja) * | 1989-09-01 | 1999-08-23 | 東ソー株式会社 | 血清アルブミンの製造方法 |
| AU1705599A (en) * | 1997-11-26 | 1999-06-15 | Allegheny University Of The Health Sciences | Methods for mobilizing hematopoietic facilitating cells and hematopoietic stem cells into the peripheral blood |
| US6175420B1 (en) * | 1998-05-20 | 2001-01-16 | Zymequest, Inc. | Optical sensors for cell processing systems |
| JP3553858B2 (ja) * | 1999-08-25 | 2004-08-11 | 東洋紡績株式会社 | 血管網類似構造体を有する細胞培養用モジュール |
| US7011761B2 (en) * | 1999-09-03 | 2006-03-14 | Baxter International Inc. | Red blood cell processing systems and methods which control red blood cell hematocrit |
| US20020020680A1 (en) * | 2000-06-20 | 2002-02-21 | Glen Jorgensen | Blood component preparation (BCP) device and method of use thereof |
| US6610002B2 (en) * | 2001-04-09 | 2003-08-26 | Medtronic, Inc. | Method for handling blood sample to ensure blood components are isolated |
| US6790371B2 (en) * | 2001-04-09 | 2004-09-14 | Medtronic, Inc. | System and method for automated separation of blood components |
| US6890291B2 (en) * | 2001-06-25 | 2005-05-10 | Mission Medical, Inc. | Integrated automatic blood collection and processing unit |
| JP2005523128A (ja) * | 2002-04-24 | 2005-08-04 | インターポア・オルソペディックス | 血液分離及び濃縮システム |
| JP2004123716A (ja) * | 2002-08-06 | 2004-04-22 | Mitsubishi Pharma Corp | 化学物質に起因する肝障害の予防及び/又は治療のための医薬 |
| JP2004099560A (ja) * | 2002-09-11 | 2004-04-02 | Hiroshi Makino | 薬剤性腎障害の予防及び/又は治療のための医薬 |
| ES2265199B1 (es) * | 2003-06-12 | 2008-02-01 | Cellerix, S.L. | Celulas madre adultas multipotentes procedentes de condrocitos desdiferenciados y sus aplicaciones. |
| EP1789540B9 (en) * | 2004-09-03 | 2012-02-22 | Moraga Biotechnology Inc. | Non-embryonic totipotent blastomer-like stem cells and methods therefor |
| WO2006070370A2 (en) * | 2004-12-29 | 2006-07-06 | Hadasit Medical Research Services & Development Limited | Stem cells culture systems |
| JP4722508B2 (ja) * | 2005-02-23 | 2011-07-13 | 日本メナード化粧品株式会社 | 多能性幹細胞の同定及び分離培養方法 |
| EP1962719A4 (en) * | 2005-08-29 | 2011-05-04 | Technion Res And Dev Of Foundation Ltd | MEDIA FOR BREEDING STEM CELLS |
| WO2009059032A2 (en) * | 2007-10-30 | 2009-05-07 | University Of Louisville Research Foundation, Inc. | Uses and isolation of very small embryonic-like (vsel) stem cells |
| US7939057B2 (en) * | 2006-01-25 | 2011-05-10 | Mount Sinai School Of Medicine | Methods and compositions for modulating the mobilization of stem cells |
| EP1991666A4 (en) * | 2006-02-27 | 2009-06-10 | Moraga Biotech Corp | NON-EMBRYONIC TOTIPOTENT STEM CELLS OF BLASTOMERIC TYPE AND METHODS |
| EP2489728A1 (en) * | 2006-06-15 | 2012-08-22 | Neostem, Inc | Processing procedure for peripheral blood stem cells |
| CA2850793A1 (en) * | 2006-10-23 | 2008-05-02 | Anthrogenesis Corporation | Methods and compositions for treatment of bone defects with placental cell populations |
| CN101688177A (zh) * | 2007-02-12 | 2010-03-31 | 人类起源公司 | 来自贴壁胎盘干细胞的肝细胞和软骨细胞;以及cd34+、cd45-胎盘干细胞富集的细胞群 |
| US20090053182A1 (en) * | 2007-05-25 | 2009-02-26 | Medistem Laboratories, Inc. | Endometrial stem cells and methods of making and using same |
| US7737175B2 (en) * | 2007-06-01 | 2010-06-15 | Duke University | Methods and compositions for regulating HDAC4 activity |
| WO2009012357A2 (en) * | 2007-07-17 | 2009-01-22 | The General Hospital Corporation | Methods to identify and enrich for populations of ovarian cancer stem cells and somatic ovarian stem cells and uses thereof |
| EP2022848A1 (en) * | 2007-08-10 | 2009-02-11 | Hubrecht Institut | A method for identifying, expanding, and removing adult stem cells and cancer stem cells |
| WO2009061024A1 (en) * | 2007-11-09 | 2009-05-14 | Rnl Bio Co., Ltd | Method for isolating and culturing adult stem cells derived from human amniotic epithelium |
| WO2009136283A2 (en) * | 2008-05-08 | 2009-11-12 | Coretherapix Slu | Multipotent adult stem cell population |
| US20120021482A1 (en) * | 2008-09-30 | 2012-01-26 | Zuba-Surma Ewa K | Methods for isolating very small embryonic-like (vsel) stem cells |
| CN101748096B (zh) * | 2008-12-17 | 2013-03-13 | 北京汉氏联合生物技术有限公司 | 亚全能干细胞、其制备方法及其用途 |
| WO2010083203A2 (en) * | 2009-01-13 | 2010-07-22 | StemBios Technologies, Inc. | Non-embryonic stem cells and uses thereof |
| CN102421467B (zh) * | 2009-03-13 | 2015-04-22 | 梅约医学教育与研究基金会 | 生物人工肝 |
| CA2835313A1 (en) * | 2010-05-07 | 2011-11-10 | Institut De Recherches Cliniques De Montreal | Gfi1b modulation and uses thereof |
| SG10201913920PA (en) * | 2010-05-12 | 2020-03-30 | Abt Holding Co | Modulation of splenocytes in cell therapy |
| CN102008650B (zh) * | 2010-12-16 | 2017-02-15 | 天津市医药科学研究所 | 一种治疗肿瘤的复方中药制剂及其制备方法 |
| WO2012139131A1 (en) * | 2011-04-08 | 2012-10-11 | The Regents Of The University Of Michigan | Autologous human adult pluripotent very small embryonic-like (hvsel) stem cell regeneration of bone and cartilage |
| US9289375B2 (en) * | 2011-08-05 | 2016-03-22 | Stemtech International Inc. | Skin care compositions containing combinations of natural ingredients |
| TWI614340B (zh) * | 2011-09-28 | 2018-02-11 | 幹細胞生物科技股份有限公司 | 體幹細胞及其製備方法 |
| EP2818544A1 (en) * | 2013-06-24 | 2014-12-31 | Stembios Technologies, Inc. | Method for counting number of stem cells in human or animal samples |
| CN105687245A (zh) * | 2014-12-13 | 2016-06-22 | 干细胞生物科技公司 | 制备注射液的方法 |
-
2015
- 2015-11-18 JP JP2017504036A patent/JP2018501189A/ja active Pending
- 2015-11-18 WO PCT/US2015/061257 patent/WO2016081553A1/en not_active Ceased
- 2015-11-18 CN CN201580043614.0A patent/CN106573018A/zh active Pending
- 2015-11-18 US US14/945,012 patent/US20160136203A1/en not_active Abandoned
- 2015-11-18 EP EP15860413.2A patent/EP3220929A4/en not_active Withdrawn
- 2015-11-18 HK HK17105713.6A patent/HK1232131A1/zh unknown
- 2015-11-18 CN CN202110799982.5A patent/CN113521107A/zh active Pending
- 2015-11-19 TW TW104138263A patent/TW201625280A/zh unknown
- 2015-11-19 TW TW110135166A patent/TW202224691A/zh unknown
-
2018
- 2018-11-02 US US16/179,522 patent/US20190105353A1/en not_active Abandoned
-
2020
- 2020-10-08 US US17/066,163 patent/US20210093676A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010056341A2 (en) * | 2008-11-12 | 2010-05-20 | The University Of Vermont And State Agriculture College | Compositions and methods for tissue repair |
| US20140219952A1 (en) * | 2010-03-23 | 2014-08-07 | The Johns Hopkins University | Methods of treatment using stem cell mobilizers |
| CN103097519A (zh) * | 2010-08-04 | 2013-05-08 | 干细胞生物科技公司 | 体干细胞 |
| US20140161774A1 (en) * | 2012-12-06 | 2014-06-12 | StemBios Technologies, Inc. | Lgr5+ SOMATIC STEM CELLS |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3220929A1 (en) | 2017-09-27 |
| US20210093676A1 (en) | 2021-04-01 |
| CN113521107A (zh) | 2021-10-22 |
| WO2016081553A1 (en) | 2016-05-26 |
| EP3220929A4 (en) | 2018-06-27 |
| TW201625280A (zh) | 2016-07-16 |
| TW202224691A (zh) | 2022-07-01 |
| JP2018501189A (ja) | 2018-01-18 |
| HK1232131A1 (zh) | 2018-01-05 |
| US20160136203A1 (en) | 2016-05-19 |
| US20190105353A1 (en) | 2019-04-11 |
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