CN106563114A - Veterinary medicine containing table vinegar and preparation method thereof - Google Patents

Veterinary medicine containing table vinegar and preparation method thereof Download PDF

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Publication number
CN106563114A
CN106563114A CN201610784134.6A CN201610784134A CN106563114A CN 106563114 A CN106563114 A CN 106563114A CN 201610784134 A CN201610784134 A CN 201610784134A CN 106563114 A CN106563114 A CN 106563114A
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China
Prior art keywords
radix
parts
vinegar
fructus
rhizoma
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CN201610784134.6A
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Chinese (zh)
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李宏强
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Individual
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Individual
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Priority to CN201610784134.6A priority Critical patent/CN106563114A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
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    • A61K33/12—Magnesium silicate
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses veterinary medicine containing table vinegar and a preparation method thereof, and belongs to the field of veterinary medicine. The veterinary medicine is prepared from the following raw materials including the table vinegar, Chinese dates, radix aucklandiae, rhizoma zingiberis, liquorice roots, dwarf lilyturf roots, endothelium corneum gigeriae galli, radix polygoni multiflori, radix angelicae sinensis, panax quinquefolium, eucommia barks, radix astragali seu hedysari, paraffin oil, linseed oil, baijiu, boys' urine, table salt, lactasin, akebia quinata, rhizoma alismatis, cortex magnoliae officinalis, fructus aurantii, old carrot seeds, steatite, garlics, wild chrysanthemum flowers, mirabilite, dajiu, tobacco leaves, old folium artemisiae argyi, pepper, white granulated sugar, unbracteolated spurge roots, semen crotonis, white pepper, rhizoma cyrtomii, mung bean powder, realgar, fructus gardenia and semen phaseoli. Various kinds of traditional Chinese medicine are used and matched, and supplement each other; the obvious effect can be achieved on diseases of dyspepsia, enteritis constipation, abdominal fullness and distention, acariasis trauma, poisoning, painful swelling of joints and the like of livestock; the cost is low; no veterinary antibiotic exists; the safety degree is high; and no toxic and side effects exist.

Description

A kind of veterinary drug containing vinegar and preparation method thereof
Technical field
The invention belongs to field of veterinary, more particularly to a kind of veterinary drug containing vinegar and preparation method thereof.
Background technology
Spectators are safe to food increasingly pays close attention to for country and society, and many raisers are big for livestock and poultry pestilence preventing and treating is only relied on Amount is used or more dosage, more scope use antibiotic, and off-drug period pertinent regulations are not strictly held in addition, causes veterinary drug to remain in a large number, Affect food safety and public health.In recent years, National agricultural department proposes " limit is anti-" or even " prohibiting anti-" (veterinary antibiotic). Therefore, using Chinese herbal medicine or Traditional Folk veterinary methods are excavated, in addition innovation and application becomes the developing direction of modern livestock and poultry pestilence.
Vinegar is indispensable flavoring agent in people's life.It is many with Sorghum vulgare Pers., Semen Tritici aestivi, rice skin, wheat bran as raw material in China Fermented brew is formed, containing the battalion such as a large amount of lactic acid, acetic acid, succinic acid, gluconic acid, citric acid, aminoacid and calcium, phosphorus, ferrum Form point.In all age, effect of preventing and curing diseases of vinegar recognized by people and is paid attention to always.The Gu hospital that China finds 《52 Bingfang》Vinegar is all used in 17 prescriptions of the diseases such as treatment hernia, scabies, calcination, hemorrhoid described in one book.The Qing Dynasty Crown land hero exists《Sui occupies diet spectrum a moment》The promoting health and curing diseases function of vinegar is summarized as in one book：" appetizing, nourishing the liver, strong muscle, warming the stomach, Relieving alcoholic intoxication helps digestion, the therapeutic method to keep the adverse QI flowing downwards exorcises evil spirits, solve all poison ".Ancient Times in China physician's Li Shizhen (1518-1593 A.D.) exists《Compendium of Materia Medica》In write：" vinegar can subside a swelling pain, Aproll gas, pathogenic toxin killing, all medicines of reason ".Therefore, vinegar all has very important effect in the treatment of many diseases.
Literature searches of the Jing to prior art finds that just Chinese equality reports application of the vinegar in aquaculture,《Herd in the north Industry》, 2004 (12)：19-19.The document reports vinegar containing abundant organic acid, various battalion such as free amino acid and vitamin Foster thing.It is preferable for Production of Livestock and Poultry and diseases prevention and treatment effect with the pharmacological action such as seasoning, aid digestion, bactericidal antiphlogistic, removing toxic substances. Zhao Congmin etc. reports application of the vinegar in livestock and poultry cultivation,《Modern agriculture》, 2001,28 (1), 41-41.The document is reported While vinegar is as flavoring agent, for raising livestock and poultry production performance and diseases prevention and treatment all have very important effect.Although It is above-mentioned to prior art discloses vinegar for Production of Livestock and Poultry and diseases prevention and treatment, but its prevention effect is not obvious enough.
The content of the invention
The technical problem to be solved is to provide a kind of veterinary drug containing vinegar, and the veterinary drug digests not for domestic animal The diseases such as good, enteritis constipation, gastrointestinal tympanites, scabies wound, poisoning rescue, arthralgia have significantly curative effect, spend low, nothing Veterinary antibiotic, safe coefficient is high, has no toxic side effect.
In order to achieve the above object, the present invention is employed the following technical solutions and is achieved.
A kind of veterinary drug containing vinegar, is made up of the raw material of following weight：30～50 parts of vinegar, 6～8 parts of Fructus Jujubae, 12～16 parts of the Radix Aucklandiae, 7～10 parts of Rhizoma Zingiberiss, 12～14 parts of Radix Glycyrrhizae, 8～10 parts of Radix Ophiopogonis, 6～11 parts of Endothelium Corneum Gigeriae Galli, Radix Polygoni Multiflori 8～13 Part, 12～14 parts of Radix Angelicae Sinensis, 9～11 parts of Radix Panacis Quinquefolii, 10～12 parts of the Cortex Eucommiae, 7～11 parts of the Radix Astragali, 0～10 part of paraffin oil, siritch 0 ～14 parts, 0～12 part of Chinese liquor, 0～15 part of urine of baby boys, 0～4 part of Sal, 0～9 part of lactasinum, 0～16 part of Caulis Akebiae, Rhizoma Alismatis 0～12 Part, 0～16 part of Cortex Magnoliae Officinalis, 0～17 part of Fructus Aurantii, 0～9 part of old carrot seed, 0～15 part of Talcum, 0～10 part of Bulbus Allii, Flos Chrysanthemi Indici 0～7 Part, 0～12 part of Natrii Sulfas, 0～10 part of big wine, 0～19 part of tobacco leaf, 0～11 part of Chen Aiye, 0～11 part of Pericarpium Zanthoxyli, white sugar 0～6 Part, 0～16 part of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 0～11 part of Fructus Crotonis, 0～11 part of Radix orixae japonicae, 0～18 part of Rhizoma Osmundae, 0～22 part of Semen phaseoli radiati powder, Realgar 0～7 Part, 0～11 part of Fructus Gardeniae, 0～9 part of Semen Phaseoli.
Preferably, a kind of veterinary drug containing vinegar, is made up of the raw material of following weight：40 parts of vinegar, Fructus Jujubae 7 Part, 14 parts of the Radix Aucklandiae, 8.5 parts of Rhizoma Zingiberiss, 13 parts of Radix Glycyrrhizae, 9 parts of Radix Ophiopogonis, 8.5 parts of Endothelium Corneum Gigeriae Galli, 10.5 parts of Radix Polygoni Multiflori, 13 parts of Radix Angelicae Sinensis, the West 10 parts of ginseng, 11 parts of the Cortex Eucommiae, 9 parts of the Radix Astragali, 9 parts of paraffin oil, 13 parts of siritch, 10 parts of Chinese liquor, 13 parts of urine of baby boys, 3.5 parts of Sal, galactenzyme Raw 7.5 parts, 15 parts of Caulis Akebiae, 10 parts of Rhizoma Alismatis, 15 parts of Cortex Magnoliae Officinalis, 16 parts of Fructus Aurantii, 7 parts of old carrot seed, 13 parts of Talcum, 9 parts of Bulbus Allii, open country 6 parts of Flos Chrysanthemi, 10 parts of Natrii Sulfas, 9 parts of big wine, 17 parts of tobacco leaf, 10 parts of Chen Aiye, 9 parts of Pericarpium Zanthoxyli, 5 parts of white sugar, 15 parts of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), bar 10 parts of bean, 10 parts of Radix orixae japonicae, 16 parts of Rhizoma Osmundae, 20 parts of Semen phaseoli radiati powder, 6 parts of Realgar, 8.5 parts of Fructus Gardeniae, 6.5 parts of Semen Phaseoli.
A kind of preparation method of the veterinary drug containing vinegar, it is comprised the following steps that：
1) old carrot seed in formula, Talcum, Bulbus Allii, big wine, Pericarpium Zanthoxyli, Fructus Crotonis, Radix orixae japonicae, Semen phaseoli radiati powder, Semen Phaseoli, breast are taken Enzyme life, Caulis Akebiae, Rhizoma Alismatis are crushed, and cross 130-140 mesh sieves, are mixed, and must mix coarse powder A；
2) Flos Chrysanthemi Indici in formula, tobacco leaf, Chen Aiye, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Rhizoma Osmundae, Sal, white sugar mix homogeneously are taken and is placed in microwave In stove microwave power be 400W, microwave frequency be 20KHz effect under irradiation 70-75s, then take out and be placed in multifunctional extracting pot Plus 6-10 times of 60%～90% ether heating and refluxing extraction measured 3 times, each 2-3 hours, united extraction liquid reclaims ethanol, dense Shorten thick paste B into；
3) Fructus Jujubae, Rhizoma Zingiberiss, Radix Ophiopogonis, Endothelium Corneum Gigeriae Galli, Radix Polygoni Multiflori, Natrii Sulfas, Fructus Gardeniae are ground into into coarse powder C, cross 120-130 mesh sieves, Mix, add vinegar, paraffin oil, siritch, Chinese liquor, urine of baby boys, Realgar to be uniformly mixed, then extract by percolation, use 75% ethanol as solvent, after immersion 30-40h, with per kilogram by 6-7ml per minute speed slowly percolation, collect coarse powder C 5～ The liquid of filtering of 7 times of weight, is spray dried to dry cream, crushes, and crosses 120-130 mesh sieves, obtains dry extract D；
4) by the Radix Aucklandiae, Radix Glycyrrhizae, Radix Angelicae Sinensis, Radix Panacis Quinquefolii, the Cortex Eucommiae, the Radix Astragali, Cortex Magnoliae Officinalis, Fructus Aurantii by formula add 8-10 times measure go from Sub- water, heating is decocted, and decocts 2-3h, obtains decoction liquor E；Filtrate after heating is decocted is filtered, and the medicinal residues after filtration add again Ionized water, soaks 50-60min, continues to decoct 2-3h, obtains decoction liquor F；Merge decoction liquor E and decoction liquor F, heating concentration surpasses Membrane filtration, leaching supernatant, filtrate is condensed into thick paste M；
5) mixing coarse powder A, thick paste B, dry extract D, thick paste M are sufficiently mixed uniformly, make ball block, use mechanical extrusion, Pill is made, wet grain is dried, is sieved, coating, obtained final product；Described dry extract D water content 1-2%；Described thick paste B is aqueous Amount 13～19%；Described thick paste M water content 14～18%；Described pill particle diameter is 6-8mm.
A kind of described veterinary drug containing vinegar is preparing dyspepsia, enteritis constipation, gastrointestinal tympanites, scabies wound, poisoning Rescue, the purposes of arthralgia.
When using, the veterinary drug only needs to admix mix homogeneously in feedstuff according to the 0.6～0.8% of domestic animal body weight.
Compared with prior art, Advantageous Effects of the invention：The present invention is coordinated using plurality of Chinese, is complemented each other, For the diseases such as domestic animals dyspepsia, enteritis constipation, gastrointestinal tympanites, scabies wound, poisoning rescue, arthralgia have significantly Effect, spends low, and without veterinary antibiotic, safe coefficient is high, has no toxic side effect.Meanwhile, add vinegar, vinegar to have in formula Resist the special efficacy such as transaminase activity and platelet aggregation.During rescue domestic animal poisoning with urea, vinegar has resisted urase Activity, slow down the decomposition of carbamide, and neutralized the ammonia in cud；In terms for the treatment of domestic animal Fengshi Guanjie, the work of vinegar Blood blood stasis dispelling, the strong muscle effect of warm bone are fairly obvious；Vinegar is used to prevent poultry anemofrigid cold and enteritis and dysentery to be primarily due to it to wound It is cold to wait pathogen that there is stronger killing effect.
Specific embodiment
Below by specific embodiment, technical scheme is further illustrated.It should be appreciated that this Bright embodiment is not limited to the following examples, and any pro forma flexible and/or change made for the present invention all will Fall into protection scope of the present invention.
Embodiment 1：For veterinary drug prepared by domestic animals dyspepsia
The veterinary drug constituted using the following raw material：Vinegar 40g, Fructus Jujubae 7g, Rhizoma Zingiberiss 8.5g, Radix Aucklandiae 14g, Radix Glycyrrhizae 13g, Radix Ophiopogonis 9g, Endothelium Corneum Gigeriae Galli 8.5g, Radix Polygoni Multiflori 10.5g, Radix Angelicae Sinensis 13g, Radix Panacis Quinquefolii 10g, Cortex Eucommiae 11g, Radix Astragali 9g, Sal 3.5g, Semen phaseoli radiati powder 20g。
When using, the veterinary drug only needs to admix mix homogeneously in feedstuff according to the 0.6% of domestic animal body weight.
Embodiment 2：For veterinary drug prepared by the constipation of domestic animal enteritis
The veterinary drug constituted using the following raw material：Vinegar 40g, Fructus Jujubae 7g, Rhizoma Zingiberiss 8.5g, Radix Aucklandiae 14g, Radix Glycyrrhizae 13g, Radix Ophiopogonis 9g, Endothelium Corneum Gigeriae Galli 8.5g, Radix Polygoni Multiflori 10.5g, Radix Angelicae Sinensis 13g, Radix Panacis Quinquefolii 10g, Cortex Eucommiae 11g, Radix Astragali 9g, lactasinum 7.5g, paraffin oil 9g, siritch 13g, Caulis Akebiae 15g, Rhizoma Alismatis 10g, Cortex Magnoliae Officinalis 15g, Fructus Aurantii 16g.
When using, the veterinary drug only needs to admix mix homogeneously in feedstuff according to the 0.7% of domestic animal body weight.
Embodiment 3：For veterinary drug prepared by domestic animal gastrointestinal tympanites
The veterinary drug constituted using the following raw material：Vinegar 40g, Fructus Jujubae 7g, Rhizoma Zingiberiss 8.5g, Radix Aucklandiae 14g, Radix Glycyrrhizae 13g, Radix Ophiopogonis 9g, Endothelium Corneum Gigeriae Galli 8.5g, Radix Polygoni Multiflori 10.5g, Radix Angelicae Sinensis 13g, Radix Panacis Quinquefolii 10g, Cortex Eucommiae 11g, Radix Astragali 9g, old carrot seed 7g, Talcum 13g, siritch 13g, Bulbus Allii 9g, Flos Chrysanthemi Indici 6g, Sal 3.5g, urine of baby boys 13g parts, Natrii Sulfas 10g, big wine 9g, tobacco leaf 17g.
When using, the veterinary drug only needs to admix mix homogeneously in feedstuff according to the 0.8% of domestic animal body weight.
Embodiment 4：For veterinary drug prepared by domestic animal scabies wound
The veterinary drug constituted using the following raw material：Vinegar 40g, Fructus Jujubae 7g, Rhizoma Zingiberiss 8.5g, Radix Aucklandiae 14g, Radix Glycyrrhizae 13g, Radix Ophiopogonis 9g, Endothelium Corneum Gigeriae Galli 8.5g, Radix Polygoni Multiflori 10.5g, Radix Angelicae Sinensis 13g, Radix Panacis Quinquefolii 10g, Cortex Eucommiae 11g, Radix Astragali 9g, Chen Aiye 10g, Pericarpium Zanthoxyli 9g, White sugar 5g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 15g, Fructus Crotonis 10g, Radix orixae japonicae 10g.
When using, the veterinary drug only needs to admix mix homogeneously in feedstuff according to the 0.6% of domestic animal body weight.
Embodiment 5：The veterinary drug for preparing is saved for Livestock poisoned
The veterinary drug constituted using the following raw material：Vinegar 40g, Fructus Jujubae 7g, Rhizoma Zingiberiss 8.5g, Radix Aucklandiae 14g, Radix Glycyrrhizae 13g, Radix Ophiopogonis 9g, Endothelium Corneum Gigeriae Galli 8.5g, Radix Polygoni Multiflori 10.5g, Radix Angelicae Sinensis 13g, Radix Panacis Quinquefolii 10g, Cortex Eucommiae 11g, Radix Astragali 9g, Chinese liquor 10g, paraffin oil 9g, White sugar 5g, siritch 13g, Rhizoma Osmundae 16g, Semen phaseoli radiati powder 20g, Flos Chrysanthemi Indici 6g.
When using, the veterinary drug only needs to admix mix homogeneously in feedstuff according to the 0.7% of domestic animal body weight.
Embodiment 6：Veterinary drug prepared by arthralgia is raiseeed for domestic animal
The veterinary drug constituted using the following raw material：Vinegar 40g, Fructus Jujubae 7g, Rhizoma Zingiberiss 8.5g, Radix Aucklandiae 14g, Radix Glycyrrhizae 13g, Radix Ophiopogonis 9g, Endothelium Corneum Gigeriae Galli 8.5g, Radix Polygoni Multiflori 10.5g, Radix Angelicae Sinensis 13g, Radix Panacis Quinquefolii 10g, Cortex Eucommiae 11g, Radix Astragali 9g, Pericarpium Zanthoxyli 9g, Realgar 6g, Fructus Gardeniae 8.5g, Semen Phaseoli 6.5g.
When using, the veterinary drug only needs to admix mix homogeneously in feedstuff according to the 0.8% of domestic animal body weight.
Embodiment 7：For the veterinary drug that domestic animal prepares with dyspepsia+gastrointestinal tympanites symptom
Veterinary drug formula is：Vinegar 40g, Fructus Jujubae 7g, Rhizoma Zingiberiss 8.5g, Radix Aucklandiae 14g, Radix Glycyrrhizae 13g, 9g Radix Ophiopogonis, Endothelium Corneum Gigeriae Galli 8.5g, Radix Polygoni Multiflori 10.5g, Radix Angelicae Sinensis 13g, Radix Panacis Quinquefolii 10g, Cortex Eucommiae 11g, Radix Astragali 9g, Sal 3.5g, Semen phaseoli radiati powder 20g, old carrot seed 7g, Talcum 13g, siritch 13g, Bulbus Allii 9g, Flos Chrysanthemi Indici 6g, urine of baby boys 13g parts, Natrii Sulfas 10g, big wine 9g, tobacco leaf 17g.
The preparation method of veterinary drug is：
1) old carrot seed in formula, Talcum, Bulbus Allii, big wine, Semen phaseoli radiati powder are taken to crush, 130 mesh sieves are crossed, is mixed, must mix thick Powder A；
2) it is 400W, microwave to take Flos Chrysanthemi Indici in formula, tobacco leaf, Sal mix homogeneously and be placed in microwave oven in microwave power Frequency is the lower irradiation 70s of 20KHz effects, then takes out and is placed in multifunctional extracting pot plus 90% ether of 8 times of amounts are heated to reflux carrying Take 3 times, 2 hours every time, united extraction liquid reclaimed ethanol, is condensed into thick paste B；
3) Fructus Jujubae, Rhizoma Zingiberiss, Radix Ophiopogonis, Endothelium Corneum Gigeriae Galli, Radix Polygoni Multiflori, Natrii Sulfas are ground into into coarse powder C, cross 130 mesh sieves, mixed, added Vinegar, siritch, urine of baby boys are uniformly mixed, and then extract by percolation, 75% ethanol as solvent are used, after immersion 35h, with every Kilogram by 6ml per minute speed slowly percolation, collect the liquid of filtering of coarse powder 6 times of weight of C, be spray dried to dry cream, crush, mistake 120 mesh sieves, obtain dry extract D；
4) Radix Aucklandiae, Radix Glycyrrhizae, Radix Angelicae Sinensis, Radix Panacis Quinquefolii, the Cortex Eucommiae, the Radix Astragali are pressed into the deionized water that formula adds 8 times of amounts, heating is decocted Boil, decoct 2h, obtain decoction liquor E；Filtrate after heating is decocted is filtered, and the medicinal residues after filtration add again deionized water, is soaked 50min, continues to decoct 2h, obtains decoction liquor F；Merge decoction liquor E and decoction liquor F, heating concentration, ultrafiltration membrance filter, in leaching Clear liquid, filtrate is condensed into thick paste M；
5) mixing coarse powder A, thick paste B, dry extract D, thick paste M are sufficiently mixed uniformly, make ball block, use mechanical extrusion, Pill is made, wet grain is dried, is sieved, coating, obtained final product；Described dry extract D water content 2%；Described thick paste B water content 16%；Described thick paste M water content 16%；Described pill particle diameter is 7mm.
Experimental example
On July 15th, 2015 to November 15, professional of agriculture has carried out by a definite date 4 on Gansu Province Jingning County pig farm 2600 pigs are divided into 13 groups by the veterinary drug preventive effect experiment of individual month, wherein 6 groups is matched group, 7 groups is embodiment 1-7, respectively Veterinary drug in daily feeding embodiment 1-7, as a result as shown in table 1：
Table 1：The veterinary drug prevention result tables of data of the present invention
Result of the test shows：The therapeutic effect of embodiment 1-7 significantly, has no toxic side effect, and cure rate is high, and inefficiency is low, can To promote the use of.
Embodiment described above is one kind preferably scheme of the present invention, not makees any pro forma to the present invention Limit.On the premise of without departing from the technical scheme described in claim, also other variants and remodeling.

Claims (2)

1. a kind of veterinary drug containing vinegar, it is characterised in that be made up of the raw material of following weight：It is 30～50 parts of vinegar, big 6～8 parts of Fructus Jujubae, 12～16 parts of the Radix Aucklandiae, 7～10 parts of Rhizoma Zingiberiss, 12～14 parts of Radix Glycyrrhizae, 8～10 parts of Radix Ophiopogonis, 6～11 parts of Endothelium Corneum Gigeriae Galli, He Shou Crow 8～13 parts, 12～14 parts of Radix Angelicae Sinensis, 9～11 parts of Radix Panacis Quinquefolii, 10～12 parts of the Cortex Eucommiae, 7～11 parts of the Radix Astragali, 0～10 part of paraffin oil, 0～14 part of siritch, 0～12 part of Chinese liquor, 0～15 part of urine of baby boys, 0～4 part of Sal, 0～9 part of lactasinum, 0～16 part of Caulis Akebiae, pool Rush down 0～12 part, it is 0～16 part of Cortex Magnoliae Officinalis, 0～17 part of Fructus Aurantii, 0～9 part of old carrot seed, 0～15 part of Talcum, 0～10 part of Bulbus Allii, wild It is 0～7 part of Flos Chrysanthemi, 0～12 part of Natrii Sulfas, 0～10 part of big wine, 0～19 part of tobacco leaf, 0～11 part of Chen Aiye, 0～11 part of Pericarpium Zanthoxyli, white 0～6 part of Saccharum Sinensis Roxb., 0～16 part of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 0～11 part of Fructus Crotonis, 0～11 part of Radix orixae japonicae, 0～18 part of Rhizoma Osmundae, 0～22 part of Semen phaseoli radiati powder, hero Yellow 0～7 part, 0～11 part of Fructus Gardeniae, 0～9 part of Semen Phaseoli.
2. a kind of method for preparing the veterinary drug containing vinegar as claimed in claim 1, it is characterised in that comprise the steps：
1) take old carrot seed in formula, Talcum, Bulbus Allii, big wine, Pericarpium Zanthoxyli, Fructus Crotonis, Radix orixae japonicae, Semen phaseoli radiati powder, Semen Phaseoli, lactasinum, Caulis Akebiae, Rhizoma Alismatis are crushed, and cross 130-140 mesh sieves, are mixed, and must mix coarse powder A；
2) take Flos Chrysanthemi Indici in formula, tobacco leaf, Chen Aiye, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Rhizoma Osmundae, Sal, white sugar mix homogeneously to be placed in microwave oven It is irradiation 70-75s under 400W, microwave frequency are 20KHz effects in microwave power, then takes out and be placed in multifunctional extracting pot plus 6- 60%～90% ether heating and refluxing extraction of 10 times of amounts 3 times, each 2-3 hours, united extraction liquid reclaims ethanol, is condensed into Thick paste B；
3) Fructus Jujubae, Rhizoma Zingiberiss, Radix Ophiopogonis, Endothelium Corneum Gigeriae Galli, Radix Polygoni Multiflori, Natrii Sulfas, Fructus Gardeniae are ground into into coarse powder C, cross 120-130 mesh sieves, mixed, Add vinegar, paraffin oil, siritch, Chinese liquor, urine of baby boys, Realgar to be uniformly mixed, then extract by percolation, use 75% ethanol Make solvent, after immersion 30-40h, with per kilogram by the speed slowly percolation of 6-7ml per minute, collect coarse powder 5～7 times of weight of C Liquid of filtering, be spray dried to dry cream, crush, cross 120-130 mesh sieves, obtain dry extract D；
4) Radix Aucklandiae, Radix Glycyrrhizae, Radix Angelicae Sinensis, Radix Panacis Quinquefolii, the Cortex Eucommiae, the Radix Astragali, Cortex Magnoliae Officinalis, Fructus Aurantii are added into the 8-10 times of deionization measured by formula Water, heating is decocted, and decocts 2-3h, obtains decoction liquor E；Will heating decoct after filtrate filter, the medicinal residues after filtration add again from Sub- water, soaks 50-60min, continues to decoct 2-3h, obtains decoction liquor F；Merge decoction liquor E and decoction liquor F, heating concentration, ultrafiltration Membrane filtration, leaching supernatant, filtrate is condensed into thick paste M；
5) mixing coarse powder A, thick paste B, dry extract D, thick paste M are sufficiently mixed uniformly, make ball block, use mechanical extrusion, made Pill, wet grain is dried, sieved, coating, obtains final product；Described dry extract D water content 1-2%；Described thick paste B water content 13 ～19%；Described thick paste M water content 14～18%；Described pill particle diameter is 6-8mm.
CN201610784134.6A 2016-08-31 2016-08-31 Veterinary medicine containing table vinegar and preparation method thereof Pending CN106563114A (en)

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Application publication date: 20170419