CN1065399A - The preparation method of medicine tonifying kidney and bone - Google Patents
The preparation method of medicine tonifying kidney and bone Download PDFInfo
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- CN1065399A CN1065399A CN 92106182 CN92106182A CN1065399A CN 1065399 A CN1065399 A CN 1065399A CN 92106182 CN92106182 CN 92106182 CN 92106182 A CN92106182 A CN 92106182A CN 1065399 A CN1065399 A CN 1065399A
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Abstract
The present invention relates to a kind of medicine tonifying kidney and bone preparation method.System adopts Chinese medicine Rhizoma Drynariae, the Radix Astragali, Herba Epimedii, the Radix Rehmanniae, Radix Salviae Miltiorrhizae, Semen Cucumidis sativi, Auricularia etc., through Chinese medicine extraction, extractum, drying, crushing screening, makes granule.Clinical effectiveness is better than domestic and international Chinese medicine and western medicine.Can effectively treat osteoporosis, repair sclerotin, again can accelerating union of bone fracture, the medicine tonifying kidney and bone taking convenience that the present invention makes has no side effect, and confirms that through zoopery therapeutic effect is remarkable.This preparation method technology is simple, and raw material sources are abundant, low cost of manufacture.
Description
The present invention relates to a kind of preparation method of Chinese medicine preparation, particularly a kind of medicine tonifying kidney and bone preparation method for the treatment of osteoporosis.
Current, one of old man's frequently-occurring disease had caused domestic and international expert's attention during osteoporosis belonged to, and is existing multiple to the medicine of primary disease, for example adopt calcium preparation, fluoride, estrogen, parathyroid hormone, calcitonin, vitamin D3 etc., androgen treatment primary disease on probation is also arranged.But in these medicines, fluoride can cause osteodynia aggravation, and side effect is bigger, and gonadal hormone can cause endocrine regulation, and is carcinogenic even, and calcitonin is non-oral administration, uses inconvenient and costs an arm and a leg.Special needs to be pointed out is that these medicines all can not make loose sclerotin reparation.Domestic once openly the report with the kidney invigorating and essence nourishing method or the kidney invigorating ruling by law treated osteoporosis (seeing 86 years the 6th phases of Journal of Traditional Chinese Medicine), and its result can only make kidney deficiency improve, and osteoporosis is not had repair.Osteoporosis is to make the disease that increases and increase with year, and the prolongation of human longevity also makes this disease sickness rate increase, directly harm humans health and even life.For this reason, the treatment osteoporosis has become medical worker's difficult problem anxious to be solved.
The purpose of this invention is to provide a kind of medicine tonifying kidney and bone preparation method that solves an above-mentioned difficult problem, not only technology is simple for it, and raw material sources are extensive, low cost of manufacture, and the medicine that adopts this method to make can make osteoporosis obtain repairing taking convenience, have no side effect, therapeutic effect is remarkable.
The object of the present invention is achieved like this: take by weighing by weight raw materials used; Radix Rehmanniae 10-35 part; Radix Rehmanniae Preparata 0-25 part; Cortex Eucommiae 0-25 part; parasitic 0-30 part; Radix Salviae Miltiorrhizae 0-30 part; Rhizoma Cibotii 0-25 part; Radix Astragali 10-80 part; cattle sunset 0-20 part; Herba Epimedii 5-35 part; Rhizoma Dioscoreae 0-15 part; Rhizoma Drynariae 5-30 part; Semen Cucumidis sativi 10-100 part; Colla Corii Asini 0-20 part; Auricularia 10-100 part; earlier that the Semen Cucumidis sativi clean dry is standby; all the other each medicines place extraction pot to decoct with water twice; add for the first time 10 times of amounts of water; decocted 40-120 minute; add for the second time 8 times of amounts of water; decocted 40-90 minute; leach filtrate then respectively; remerge filtrate twice; left standstill 24 hours, and after vacuum concentration becomes thick shape, added standby Semen Cucumidis sativi and add medicinal paste while stirring; stir until becoming paste; vacuum drying becomes dried cream under 80 ℃ of temperature being no more than, and dried cream is mixed on demand with sucrose, pulverized 100 mesh sieves after; in comminutor, add 75% alcohol and granulate, through being no more than 80 ℃ of temperature dryings; packing is finished product.
Because the present invention selects for use Chinese medicine to process granular preparation, so taking convenience, its raw material sources are extensive, and technology is simple, and equipment is few, so low cost of manufacture.This method is compared with the traditional decocting medicine method, can extract former medicine 12-14%, and the traditional decocting medicine method can only be extracted 8-10%, and the principles of formulating prescriptions are to tonify Qi of the kidney to invigorate blood circulation, and are evident in efficacy through clinical verification, and have no side effect.This medicine tonifying kidney and bone except that to osteoporosis and by its lumbago and skelalgia that causes effective in cure, also can treat diseases such as osteonecrosis, particularly femur necrosis, anemia of cancer, union of fracture, hyperosteogeny, chronic nephritis, rheumatism and rheumatoid.
Describe preparation method of the present invention in detail below in conjunction with embodiment.
Embodiment 1
Select the Radix Rehmanniae 15 grams, Radix Salviae Miltiorrhizae 10 grams, the Radix Astragali 10 grams, Herba Epimedii 10 grams, Rhizoma Drynariae 10 grams, Semen Cucumidis sativi 20 grams, Auricularia 10 grams, Colla Corii Asini 20 grams for use, after taking by weighing according to quantity, earlier that the Semen Cucumidis sativi clean dry is standby.All the other each medicines place extraction pot to decoct with water twice.For the first time add 10 times of amounts of water, decocted 40-120 minute, add 8 times of amounts of water for the second time, decocted 40-90 minute, leach filtrate then respectively, remerge filtrate twice.Left standstill 24 hours, and after vacuum concentration becomes thick shape, added standby Semen Cucumidis sativi.Add medicinal paste while stirring, stir until becoming paste.Vacuum drying becomes dried cream under 80 ℃ of temperature being no more than, and dried cream is mixed on demand with sucrose, makes that sugariness is suitable get final product, pulverizes then to reach 100 mesh sieves, adds 75% alcohol granulation in comminutor, through being no more than 80 ℃ of temperature dryings, packing and be finished product.Said preparation cures mainly the first example of curing the disease of osteoporosis.
Embodiment 2
Select for use Radix Rehmanniae Preparata 10 gram, the Radix Rehmanniae 10 grams, Radix Salviae Miltiorrhizae 10 grams, Rhizoma Dioscoreae 5 grams, Rhizoma Drynariae 5 grams, Rhizoma Cibotii 5 grams, Semen Cucumidis sativi 10 grams, cattle sunset 5 gram, Auricularia 5 grams, the Radix Astragali 10 grams, Herba Epimedii 5 grams,, its technology manufacture process is identical with embodiment 1.Be mainly used in and consolidate osteoporotic curative effect and preventive dosage.
Embodiment 3
Select Radix Rehmanniae Preparata 25 grams, the Radix Rehmanniae 35 grams, the Cortex Eucommiae 25 grams, Radix Salviae Miltiorrhizae 20 grams, the Radix Astragali 80 grams, Herba Epimedii 35 grams, Auricularia 80 grams, Semen Cucumidis sativi 100 grams, Rhizoma Drynariae 30 grams for use, its technology manufacture process is identical with embodiment 1.Be mainly used in severe solid osteoporosis, fracture and osteonecrosis patient.
Embodiment 4
Select the Cortex Eucommiae 25 grams, parasitic 30 grams, Radix Salviae Miltiorrhizae 20 grams, Rhizoma Cibotii 25 grams, Herba Epimedii 20 grams, Rhizoma Drynariae 20 grams, Semen Cucumidis sativi 20 grams, Auricularia 30 grams, the Radix Astragali 30 grams for use, its technology manufacture process is identical with embodiment 1.Be mainly used in osteoporosis and merge rheumatoid, rheumatism.
Embodiment 5
Select cattle sunset 20 gram, Radix Salviae Miltiorrhizae 30 grams, Radix Rehmanniae Preparata 20 grams, the Radix Rehmanniae 20 grams, the Radix Astragali 30 grams, Herba Epimedii 20 grams, Auricularia 10 grams, Semen Cucumidis sativi 15 grams, Rhizoma Drynariae 25 grams for use, its technology manufacture process is identical with embodiment 1.Be mainly used in osteoporosis bone spiral hypertrophy case.
Embodiment 6
Select Colla Corii Asini 20 grams, Herba Epimedii 35 grams, Rhizoma Dioscoreae 15 grams, Radix Rehmanniae Preparata 25 grams, the Radix Astragali 60 grams, the Radix Rehmanniae 25 grams, Radix Salviae Miltiorrhizae 30 grams, Rhizoma Drynariae 15 grams, Semen Cucumidis sativi 10 grams, Auricularia 30 grams for use, its technology manufacture process is identical with embodiment 1.Be mainly used in anemia of cancer and chronic nephritis patient.
Zoopery
1, selecting rat for use is the moulding animal.
2, formative method adopts retinoic acid method, long bone from disconnected method.
3, result of the test:
The retinoic acid method
A, simple moulding group: it is irregular that the attenuation of long bone sclerotin appears in animal, and bone trabecula attenuates even disappears;
B, modeling and adding are given beneficial bone spirit group: sclerotin does not have significant change, and visible osteoblast active proliferation, angiogenesis, calcium deposition;
The blank group of administration not after C, the moulding: the attenuation of long bone sclerotin is irregular, and bone trabecula does not see, and does not promptly have the phenomenon of reparation;
Dispensing treatment group after D, the simple moulding: the long bone cortical bone is repaired, and also can be clear that bone trabecula, and presents the calcium deposition.
Long bone is from disconnected method
A, with the rat long bone from having no progeny, make it repair (blank) naturally;
B, the contrast of Chinese medicine Cortex torricelliae tiliifoliae;
C, throwing medicine tonifying kidney and bone
The result throws medicine tonifying kidney and bone C group, and healing time is significantly shorter than two groups of A, B.
Usage and dosage: boiled water is taken after mixing it with water, one time one bag, two to three times on the one, the child follows the doctor's advice.
Claims (1)
1; a kind of medicine tonifying kidney and bone preparation method; it is characterized in that taking by weighing by weight with raw materials used; Radix Rehmanniae 10-35 part; Radix Rehmanniae Preparata 0-25 part; Cortex Eucommiae 0-25 part; parasitic 0-30 part; Radix Salviae Miltiorrhizae 10-30 part; Rhizoma Cibotii 0-25 part; Radix Astragali 10-80 part; cattle sunset 0-20 part; Herba Epimedii 5-35 part; Rhizoma Dioscoreae 0-15 part; Rhizoma Drynariae 5-30 part; Semen Cucumidis sativi 10-100 part; Colla Corii Asini 0-20 part; Auricularia 10-100 part; earlier that the Semen Cucumidis sativi clean dry is standby; all the other each medicines place extraction pot to decoct with water twice; add for the first time 10 times of amounts of water; decocted 40-120 minute; add for the second time 8 times of amounts of water; decocted 40-90 minute; leach filtrate then respectively; remerge filtrate twice; left standstill 24 hours; after vacuum concentration becomes the thick paste shape; adding standby Semen Cucumidis sativi adds medicinal paste while stirring and stirs until becoming paste; vacuum drying becomes dried cream under 80 ℃ of temperature being no more than; dried cream is mixed on demand with sucrose; after pulverizing 100 mesh sieves; in comminutor, add 75% alcohol and granulate, through being no more than 80 ℃ of temperature dryings; packing is finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN92106182A CN1047082C (en) | 1992-05-15 | 1992-05-15 | Process of preparation of medicine tonifying kidney and bone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN92106182A CN1047082C (en) | 1992-05-15 | 1992-05-15 | Process of preparation of medicine tonifying kidney and bone |
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| Publication Number | Publication Date |
|---|---|
| CN1065399A true CN1065399A (en) | 1992-10-21 |
| CN1047082C CN1047082C (en) | 1999-12-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN92106182A Expired - Lifetime CN1047082C (en) | 1992-05-15 | 1992-05-15 | Process of preparation of medicine tonifying kidney and bone |
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| Country | Link |
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| CN (1) | CN1047082C (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1038813C (en) * | 1993-07-02 | 1998-06-24 | 周勇 | Traditional Chinese medicine for curing osteoporosis |
| CN1056769C (en) * | 1996-02-09 | 2000-09-27 | 王成武 | Prescription for bone setting capsule and process thereof |
| WO2003105829A1 (en) * | 2002-06-18 | 2003-12-24 | Shanghai Institute Of Pharmaceutical Industry | A formulation of traditional chinese medicine for preventing and treating osteoporosis |
| CN1323677C (en) * | 2004-06-03 | 2007-07-04 | 陈根生 | Medicine for osteoporosis |
| CN100418553C (en) * | 2005-12-09 | 2008-09-17 | 康辰医药股份有限公司 | Preparation for treating osteoporosis and preparation method thereof |
| CN101361893B (en) * | 2008-09-16 | 2010-11-03 | 东莞市赫尔逊生物科技有限公司 | Traditional Chinese medicine combination for preventing and treating osteoporosis |
| CN1943691B (en) * | 2005-10-08 | 2011-04-13 | 周小明 | A Chinese traditional medicinal composition for treatment of osteoporosis and its preparation method |
| CN101579389B (en) * | 2008-05-15 | 2011-08-31 | 北京北大维信生物科技有限公司 | Medicinal composition for treating osteoporosis |
| CN101455375B (en) * | 2008-11-27 | 2012-07-04 | 成都润馨堂药业有限公司 | Nutrient health-care products and preparation method thereof |
| CN104623064A (en) * | 2015-02-18 | 2015-05-20 | 辽宁康辰药业有限公司 | Gushukang preparation |
| CN104906250A (en) * | 2015-06-16 | 2015-09-16 | 辽宁康辰药业有限公司 | Application of gushukang (Chinese character) in preparation of medicines for treating osteonecrosis diseases |
-
1992
- 1992-05-15 CN CN92106182A patent/CN1047082C/en not_active Expired - Lifetime
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1038813C (en) * | 1993-07-02 | 1998-06-24 | 周勇 | Traditional Chinese medicine for curing osteoporosis |
| CN1056769C (en) * | 1996-02-09 | 2000-09-27 | 王成武 | Prescription for bone setting capsule and process thereof |
| WO2003105829A1 (en) * | 2002-06-18 | 2003-12-24 | Shanghai Institute Of Pharmaceutical Industry | A formulation of traditional chinese medicine for preventing and treating osteoporosis |
| CN1323677C (en) * | 2004-06-03 | 2007-07-04 | 陈根生 | Medicine for osteoporosis |
| CN1943691B (en) * | 2005-10-08 | 2011-04-13 | 周小明 | A Chinese traditional medicinal composition for treatment of osteoporosis and its preparation method |
| CN100418553C (en) * | 2005-12-09 | 2008-09-17 | 康辰医药股份有限公司 | Preparation for treating osteoporosis and preparation method thereof |
| CN101579389B (en) * | 2008-05-15 | 2011-08-31 | 北京北大维信生物科技有限公司 | Medicinal composition for treating osteoporosis |
| CN101361893B (en) * | 2008-09-16 | 2010-11-03 | 东莞市赫尔逊生物科技有限公司 | Traditional Chinese medicine combination for preventing and treating osteoporosis |
| CN101455375B (en) * | 2008-11-27 | 2012-07-04 | 成都润馨堂药业有限公司 | Nutrient health-care products and preparation method thereof |
| CN104623064A (en) * | 2015-02-18 | 2015-05-20 | 辽宁康辰药业有限公司 | Gushukang preparation |
| CN104623064B (en) * | 2015-02-18 | 2017-11-14 | 辽宁康辰药业有限公司 | A kind for the treatment of osteoporosis preparation |
| CN104906250A (en) * | 2015-06-16 | 2015-09-16 | 辽宁康辰药业有限公司 | Application of gushukang (Chinese character) in preparation of medicines for treating osteonecrosis diseases |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1047082C (en) | 1999-12-08 |
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