CN1052880C - "Zhennaoning" capsule for treating angioneurotic headache - Google Patents

Abstract

The present invention relates to a 'Zhennaoning' capsule for treating angioneurotic headache, which is prepared from Chinese herbal medicines such aschuanxiong rhizome, red sage root, pig brain, gastrodia tuber and asarum herb through processing. The capsule realizes the efficacy of calming the wind and relieving pain through promoting the circulation of qi and blood, calming the liver, sobering the brain and relieving anxiety for tranquilization and sedation.

Description

The capsular preparation method of treatment angioneurotic headache

The invention belongs to a kind of preparation method of Chinese patent medicine, the capsular preparation method of in particular a kind of treatment angioneurotic headache.

At present, headache is common clinically subjective symptoms, is found in that modern medicine is inside and outside, among each section's disease such as nerve and face, and especially the medicine of angioneurotic headache disease being only limited to ease pain alleviates patient's pain, can not radical curing of disease.

The objective of the invention is to: provide a kind of have arteriosclerosis, hypertension and the caused angioneurotic headache of some symptoms and chronic headache high partially based on liver-yang, the headache of two, three class diseases such as the resistance of the folder stasis of blood, blood deficiency or expectorant are turbid is an object, has " mark ", " basis " double capsular preparation method of controlling effect.

Solution of the present invention is: selecting Rhizoma Chuanxiong, Rhizoma Ligustici, Herba Asari, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae, Pulvis Cornus Bubali Concentratus, Radix Salviae Miltiorrhizae, Radix Puerariae, Medulla sus domestica for use is pharmaceutical raw material, process pick → mixing → pulverizing → enzymolysis → mixing sterilization packing technical process is made capsular, and the weight proportion of above-mentioned all kinds of medical materials is:

15 parts of 7 parts of Rhizoma Chuanxiongs, 5 parts of Rhizoma Ligusticis, 5 parts of Herba Asaris, 7 parts of the Radixs Angelicae Dahuricae, 1 part in Rhizoma Gastrodiae, 7 parts of Radix Salviae Miltiorrhizaes, 7 parts of Radix Puerariaes, Pulvis Cornus Bubali Concentratus 1, Medulla sus domestica.

Make the capsular production method of the present invention according to above-mentioned prescription:

1, pick Rhizoma Chuanxiong, Rhizoma Ligustici, Herba Asari, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae, Radix Salviae Miltiorrhizae, Radix Puerariae carry out sensory testly, get the medical material decontamination earth that meets pharmacopeia regulation, after cleaning, through low temperature less than 60 ℃ of dryings;

2, get Rhizoma Chuanxiong, Rhizoma Ligustici, Herba Asari, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae, Radix Salviae Miltiorrhizae, Radix Puerariae dried feed, it is standby that 100 mesh sieves were pulverized in mixing;

3, get the recipe quantity Pulvis Cornus Bubali Concentratus, cross 100 mesh sieves, standby;

4, get fresh Medulla sus domestica decontamination, clean, rub, with acetone defat cholesterol reduction, totally three times, filtrate merging is reclaimed acetone, filtering residue is in dry below 80 ℃, be ground into fine powder, get this powder, transfer pH value to 6.5-7.0 with distilled water furnishing pulpous state, constant temperature water bath adds protease for 45 ℃, after the hydrolysis 16 hours, in vacuum drying, pulverizing below 60 ℃, it is standby to cross 100 mesh sieves;

5, carry out abundant mixing sterilization by the weight ratio of prescription behind said medicine process pick process, mixed process, crushing process, the enzymolysis process and be distributed into capsule.

Be preparation method of the present invention and embodiment below:

Embodiment

Recipe quantity: Rhizoma Chuanxiong 700 grams, Rhizoma Ligustici 500 grams, Herba Asari 500 grams, the Radix Angelicae Dahuricae 700 grams, Rhizoma Gastrodiae 100 grams, Pulvis Cornus Bubali Concentratus 100 grams, Radix Salviae Miltiorrhizae 700 grams, Radix Puerariae 700 grams, Medulla sus domestica 1500 grams;

Rhizoma Chuanxiong, Rhizoma Ligustici, Herba Asari, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae, Radix Salviae Miltiorrhizae, Radix Puerariae decontamination, earth, after cleaning, less than 60 ℃ of dryings, dry back is pressed recipe quantity and mixed pulverizing, crosses 100 mesh sieves, and is standby through low temperature;

Pulvis Cornus Bubali Concentratus is crossed 100 mesh sieves, and is standby;

Fresh Medulla sus domestica is cleaned through decontamination, rubs, with acetone defat cholesterol reduction, totally three times, filtrate merging is reclaimed acetone, filtering residue is ground into fine powder in dry below 80 ℃, gets this powder distilled water furnishing pulpous state, transfer pH value to 6.5-7.0,45 ℃ of constant temperature water baths add protease, and hydrolysis is after 16 hours, again with it in vacuum drying, pulverizing below 60 ℃, cross 100 mesh sieves, standby;

Get above-mentioned Rhizoma Chuanxiong, Rhizoma Ligustici, Herba Asari, the Radix Angelicae Dahuricae, Rhizoma Gastrodiae, Radix Salviae Miltiorrhizae, Radix Puerariae, Pulvis Cornus Bubali Concentratus, Medulla sus domestica hydrolysate dry powder and cross 100 mesh sieves, fully be mixed, sterilization, the packing soft gelatin capsule is promptly.

Claims (1)

1, the capsular preparation method of a kind of treatment angioneurotic headache is characterized in that:

A, 7 parts of pick Rhizoma Chuanxiongs, 5 parts of Rhizoma Ligusticis, 5 parts of Herba Asaris, 7 parts of the Radixs Angelicae Dahuricae, 1 part in Rhizoma Gastrodiae, 7 parts of Radix Salviae Miltiorrhizaes, 7 parts of Radix Puerariaes, decontamination earth after cleaning,, mixes and pulverized 100 mesh sieves less than 60 ℃ of dryings through low temperature, and is standby;

B, get 1 part of Pulvis Cornus Bubali Concentratus, cross 100 mesh sieves, standby;

C, 15 parts of decontaminations of fresh Medulla sus domestica are cleaned, and rub, with acetone defat cholesterol reduction totally three times, filtrate merging is reclaimed acetone, and filtering residue is in dry below 80 ℃, be ground into fine powder, get this fine powder with distilled water furnishing pulpous state, transfer PH to 6.5-7.0, constant temperature water bath adds protease for 45 ℃, after the hydrolysis 16 hours, in vacuum drying, pulverizing below 60 ℃, cross 100 mesh sieves, standby;

With above-mentioned prepared product pick, mixing, cross 100 mesh sieves, mixing, sterilization, capsule is made in packing.