CN106538534A - A kind of complex composition containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate - Google Patents
A kind of complex composition containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate Download PDFInfo
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- CN106538534A CN106538534A CN201610945674.8A CN201610945674A CN106538534A CN 106538534 A CN106538534 A CN 106538534A CN 201610945674 A CN201610945674 A CN 201610945674A CN 106538534 A CN106538534 A CN 106538534A
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- Prior art keywords
- metrafenone
- cyano
- amino
- phenylancryic acetate
- complex composition
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aldehyde or keto groups, or thio analogues thereof, directly attached to an aromatic ring system, e.g. acetophenone; Derivatives thereof, e.g. acetals
Abstract
The invention discloses a kind of complex composition containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate, effective active composition is made up of metrafenone and 2-cyano-3-amino-3-phenylancryic acetate, and the weight ratio of metrafenone and 2-cyano-3-amino-3-phenylancryic acetate is 20:1～1:40.Powdery mildew and head blight excellent on built composition for preventing and controlling wheat of the present invention, expands fungicidal spectrum, and the lasting period is long, to wheat safety.There is significant synergistic function after metrafenone and 2-cyano-3-amino-3-phenylancryic acetate compounding, Pesticide use amount can be reduced, use cost is reduced, mitigate the pollution to environment, delay the drug-fast generation of pathogen, increase the Pesticide use life-span.
Description
Technical field
The present invention relates to pesticide complex composition and its application, specifically with metrafenone and 2-cyano-3-amino-3-phenylancryic acetate to have
The binary complex of effect active component compounding, is mainly used in the preventing and treating of powdery mildew and head blight on wheat.
Background technology
Metrafenone, belongs to Benzophenones bactericide, and the mechanism of action is the dynamic egg of cytoskeleton-flesh for directly acting on germ
In vain so as to be destroyed and disintegrate, cause the abnormal branch of mycelium, while slowing down growth, so as to reach the purpose of controlling disease,
There is good prevention effect to diseases such as powdery mildews.
2-cyano-3-amino-3-phenylancryic acetate, belongs to cyanoacrylate bactericide, with the spy such as efficient, micro- poison, low-residual, environmentally friendly
Point, to having protection and therapeutic action by the microbial all kinds of plant diseases of reaping hook, can be applicable to preventing and treating reaping hook microbial little
Wheat head blight, cotton wilt, bakanae disease of rice, watermelon blight etc..
The long-time of agricultural chemicals single variety continuously increases risk using easily generation resistance risk and consumption, and then increases into
Sheet and carrying capacity of environment, and pass through different pesticide species compound screenings and go out the complex composition with notable synergistic function, no
It is only capable of reducing Pesticide use amount, reduces use cost, reduce resistance risk, moreover it is possible to reduces potential environmental risk, increase agricultural chemicals
Service life.
The present inventor during further investigation metrafenone and 2-cyano-3-amino-3-phenylancryic acetate compounded formula, surprisingly benzene bacterium
Ketone and 2-cyano-3-amino-3-phenylancryic acetate are compounded, and the powdery mildew and head blight on wheat are had in the range of certain compound proportion significant
Synergistic function, after further study, completes the present invention.
The content of the invention
It is an object of the invention to provide a kind of component is rationally, obvious synergy, bactericidal effect are outstanding, fungicidal spectrum
Extensively, the lasting period is long, and drug cost is low, and pathogen can be delayed to develop immunity to drugs, and the pesticide complex composition to wheat safety.
Another object of the present invention is to provide a kind of complex composition preparation formulation containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate.
It is still another object of the present invention to provide in powdery mildew and head blight of the above-mentioned complex composition on preventing and treating wheat
Application.
Technical scheme：For achieving the above object, the present invention provides a kind of answering containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate
With composition, effective active composition is made up of metrafenone and 2-cyano-3-amino-3-phenylancryic acetate, and the weight ratio of metrafenone and 2-cyano-3-amino-3-phenylancryic acetate is 20:1～
1:40, the weight ratio of preferred metrafenone and 2-cyano-3-amino-3-phenylancryic acetate is 10:1～1:20, the most preferably weight ratio of metrafenone and 2-cyano-3-amino-3-phenylancryic acetate
For 1:4.
In complex composition of the present invention, the gross weight percentage composition of metrafenone and 2-cyano-3-amino-3-phenylancryic acetate is 1%～80%, and remaining is
Allow to use and acceptable auxiliary element in agricultural chemicals.
Complex composition of the present invention can be prepared in suitable agricultural production any formulation for using, and reasonable formulation has
Aqueous suspension agent, oil-suspending agent, aqueous emulsion, microemulsion, water dispersible granules, ultra low volume liquids.
In aqueous suspension agent, it is possible to use auxiliary element have：It is the optional freely double naphthalenesulfonate formaldehyde condensation compounds of dispersant, poly-
Carboxylate, lignosulfonates, alkyl naphthalene formaldehyde condensate sulfonates, alkylphenol-polyethenoxy base ether phosphate, alkyl phenol gather
Oxyethylene group ether sulfonate, phenethyl phenol polyoxyethylene groups ether phosphate, alkyl polyoxyethylene ether sulfonate, polyoxyethylene polyoxy
The mixing of one or more in propenyl ether block copolymer, pull open powder, alkylpolyoxyethylene phosphate；Wetting agent
Optional freely polyether-modified polysiloxane, alkylphenol-polyethenoxy base ether formaldehyde condensation products sulfate, phenethyl phenol polyoxy
Vinyl ethers phosphate, alkyl sulfate, alkylsulfonate, alkylnaphthalene sulfonate, alkyl phenol formaldehyde resin polyoxyethylene ether, three
The mixing of one or more in phenethyl phenol polyoxyethylene polyoxypropylene block polymer；Thickener is optional freely Arabic
Glue, xanthans, carboxymethylcellulose calcium, polyvinyl alcohol, gaseous silicon oxide, Magnesiumaluminumsilicate, carboxyethyl cellulose, carboxylic propyl group fiber
Element, PAA, polyvinylpyrrolidone, Sodium Polyacrylate, polyvinyl acetate, bentonite, white carbon, attapulgite, CMC
In the mixing of one or more；It is the optional KF88 of Kathon CG freely of preservative, formaldehyde, benzoic acid, Sodium Benzoate, potassium sorbate, different
The mixing of one or more in thiazolinone；The optional silicone oil freely of defoamer, silicone compound, C10-20Saturated fat acids
Compound, C8-10The mixing of one or more in aliphatic alcohols, hexanol, butanol, octanol；Optional glycerine-the second freely of antifreezing agent
The mixing of one or more in ether diglycol, methyl propylene diglycol, ethylene glycol, propane diols, glycerine, urea；Water is
Deionized water.
In oil-suspending agent, it is possible to use auxiliary element have：The optional block copolymers of EO-PO freely of dispersant, polycarboxylic acids
Salt, lignosulfonates, alkylnaphthalene sulfonate, TERSPERSE 2020 (Huntsman Corporation of U.S. HUNTSMAN products, alkylnaphthalene
Sulfonates) in the mixing of one or more；Optional BY freely (castor oil polyoxyethylene ether) the series emulsifying agent of emulsifying agent
(BY-110, BY-125, BY-140), Nongru-700 # (common names：Alkyl phenol formaldehyde resin polyoxyethylene ether), agriculture breast 2201, this
Disk -60# (common names：Sorbitan monostearate), Tween-60 # (common names：Sorbitan monostearate polyoxy second
Alkene ether), agriculture breast 1601# (common name：Phenethyl phenol polyoxyethylene poly-oxygen propylene aether), TERSPERSE4894 (U.S.'s Hensel step
Company produce) in the mixing of one or more；Thickener is may be selected from such as organobentonite, white carbon, polyvinyl alcohol, magnesium silicate
The mixing of one or more in aluminium；One kind in the optional ethylene glycol freely of antifreezing agent, propane diols, glycerine, urea, sodium chloride
Or several mixing；The optional turpentine-based vegetable oil freely of decentralized medium, methyl oleate, soybean oil, peanut oil, mineral oil, solvent
Oily (the trade mark：S-150, S-180, S-200), the mixing of one or more in formicester palm oil.
In aqueous emulsion, it is possible to use auxiliary element have：The optional ethylene oxide adduct freely of emulsifying agent, polyoxyethylene nonyl phenyl
Ethene ether phosphate, triphenoethyl benzene phenol polyethenoxy ether phosphate, Nongru-700 # (common names：Alkylphenol-formaldehyde resin polyoxy
Vinethene), agriculture breast 2201#, this disk -60# (common names：Span60), Tween-60 # (common names：Polyoxy second
Alkene Span60), TX-10 (common names：Octyl phenol polyoxyethylene (10) ether), agriculture breast 1601# (common name：Three
Phenethyl phenol polyoxyethylene polyoxypropylene block polymer), agriculture breast 600#, the mixing of one or more in agriculture breast 400#；
The optional ethanol freely of solvent, normal propyl alcohol, isopropanol, butanol, isobutanol, sec-Butyl Acetate, ethylene glycol monoethyl ether, dimethylbenzene, three
Toluene, toluene, cyclohexanone, the solvent naphtha (trade mark：S-150, S-180, S-200) in the mixing of one or more；Stabilizer can
Selected from such as epoxidized soybean oil, epoxidized linseed oil, pentaerythrite, xylitol, 2,6 di tert butyl 4 methyl phenol, butylhydroxy
The mixing of one or more in anisole；In the optional ethylene glycol freely of antifreezing agent, propane diols, glycerine, urea, sodium chloride
The mixing of one or more；In the optional cellulose ether freely of thickener, xanthans, polyvinyl alcohol, organobentonite, aluminium-magnesium silicate
The mixing of one or more；The optional silicone oil freely of defoamer, silicone compound, C10-20Saturated fat acids compound,
C8-10The mixing of one or more in aliphatic alcohols, hexanol, butanol, octanol；The optional formaldehyde freely of preservative, benzoic acid, benzene
The mixing of one or more in sodium formate, water are deionized water.
In microemulsion, it is possible to use auxiliary element have：Optional calcium dodecyl benzene sulfonate (the agriculture breast freely of emulsifying agent
500#), Nongru-700 #, agriculture breast 2201#, this disk-60#, polysorbate60-#, TX-10, agriculture breast 1601# (common name：Phenethyl phenol
Polyoxyethylene poly-oxygen propylene aether), agriculture breast 600#, the mixing of one or more in agriculture breast 400#；The optional first freely of assistant for emulsifying agent
The mixing of one or more in alcohol, isopropanol, n-butanol, ethanol；The optional dimethylbenzene freely of solvent, cyclohexanone, solvent naphtha (board
Number：S-150, S-180, S-200), mineral oil, turpentine-based vegetable oil, turpentine oil, methyl oleate, the one kind in sec-butyl acetate
Or several mixing；One or more in the optional ethylene glycol freely of antifreezing agent, propane diols, glycerine, urea, sodium chloride it is mixed
Close；The optional silicone oil freely of defoamer, silicone compound, C10-20Saturated fat acids compound, C8-10Aliphatic alcohols, hexanol,
The mixing of one or more in butanol, octanol；The optional epoxidized soybean oil freely of stabilizer, triphenyl phosphite, epoxy chloropropionate
The mixing of one or more in alkane；Water is deionized water.
In water dispersible granules, it is possible to use auxiliary element have：The optional sodium lignin sulfonate freely of dispersant, polycarboxylate
Class, lauryl alcohol polyethylene glycol oxide base ether sodium sulfate, alkyl naphthalene formaldehyde condensate sulfonates, alkyl polyoxyethylene ether sulfonate, alkyl
Phenol polyethenoxy base ether formaldehyde condensation products, polyoxyethylene polyoxypropylene base ether block copolymers, alkylpolyoxyethylene phosphorus
The mixing of one or more in acid esters；The optional neopelex freely of wetting agent, pull open powder, alkylphenol-formaldehyde resin
The mixing of one or more in polyoxyethylene ether sulfate, alkylphenol-polyethenoxy base ether, Nonyl pheno base ether；Collapse
One or more in the optional ammonium sulfate freely of solution agent, sodium sulphate, polyvinylpyrrolidone, starch and its derivative, bentonite
Mixing；The optional kaolin freely of filler, diatomite, precipitated calcium carbonate, white carbon, attapulgite, cornstarch, sepiolite,
The mixing of one or more in calcite, silica, pyrophyllite, xylitol, montmorillonite, potter's clay.
In ultra low volume liquids, it is possible to use auxiliary element have：The optional aliphatic alcohol polyethenoxy freely of surfactant
Ether, APES, alkylaryl polyoxyethylene polyoxypropylene ether again, APES phosphate, phenethyl
Phenol polyethenoxy ether phosphate, alkylaryl polyoxyethylene polyoxypropylene ether again phosphate, castor oil polyoxyethylene ether, dodecyl
The mixing of one or more in benzene sulfonic acid calcium；In the optional azone freely of bleeding agent, thiophene ketone, fast penetrant T, isophorone
The mixing of one or more；One or more in the optional gibberellic acid freely of poisoning palliative, study on brassinolide, compound sodium nitrophenolate
Mixing；The optional ethylo benzene freely of solvent, trimethylbenzene, soybean oil, rapeseed oil, corn oil, loose base oil, methyl oleate, ethyl oleate,
Methyl alcohol, ethanol, acetone, N,N-dimethylformamide, DMAC N,N' dimethyl acetamide, ethylene glycol, propane diols, glycerine, isooctanol, just
The mixing of one or more in octanol.
The production technology of the various application forms of the complex composition belongs to existing known technology, will not be described here.
Compared with prior art, it is an advantage of the current invention that：
1st, two kinds of effective active composition compoundings of metrafenone and 2-cyano-3-amino-3-phenylancryic acetate have significant synergistic function, than single dose
Exclusive use significantly improves the prevention effect to powdery mildew on wheat and head blight, expands fungicidal spectrum.
2nd, two kinds of effective active composition compoundings of metrafenone and 2-cyano-3-amino-3-phenylancryic acetate, reduce Pesticide use amount, reduce and use into
This, alleviates the pollution to environment.
3rd, two kinds of effective active composition compoundings of metrafenone and 2-cyano-3-amino-3-phenylancryic acetate, the mechanism of action are different, and action site increases,
Delay the drug-fast generation of pathogen, increased the Pesticide use life-span.
Specific embodiment
Essence for a better understanding of the present invention, is described further to present disclosure with reference to embodiment,
But limitation of the present invention can not be considered as, described below is only used for explaining the present invention, for without departing from spirit of the invention and principle
Modification, replacement or the improvement made, belongs to the scope of protection of present invention.
(1) Formulation Example
In following examples, each component percentage composition is weight percentage.
One 21% metrafenone 2-cyano-3-amino-3-phenylancryic acetate aqueous suspension agent of embodiment
Metrafenone 20%, 2-cyano-3-amino-3-phenylancryic acetate 1%, phenethyl phenol polyoxyethylene groups ether phosphate (dispersant) 7%, alkylnaphthalene sulphur
Hydrochlorate (wetting agent) 5%, Sodium Benzoate (preservative) 0.2%, silicone oil (defoamer) 0.2%, hydroxymethyl cellulose (thickener)
2%th, ethylene glycol (antifreezing agent) 2.5%, deionized water supplies 100%.Above-mentioned material is mixed in proportion, the dispersion of Jing high speed shears
Uniformly, in sand mill after sand milling, you can 21% metrafenone 2-cyano-3-amino-3-phenylancryic acetate aqueous suspension agent is obtained.
2 11% metrafenone 2-cyano-3-amino-3-phenylancryic acetate oil-suspending agent of embodiment
Metrafenone 10%, 2-cyano-3-amino-3-phenylancryic acetate 1%, Nongru-700 # (emulsifying agent) 10%, EO-PO block copolymers (dispersant)
6%th, white carbon (thickener) 2%, glycerine (antifreezing agent) 1.5%, formicester palm oil (decentralized medium) supply 100%.Will
Above-mentioned material mixes in proportion, is uniformly dispersed Jing high speed shear, in sand mill after sand milling, you can 11% metrafenone cyanogen alkene is obtained
Bacterium ester oil suspending agent.
The metrafenone 2-cyano-3-amino-3-phenylancryic acetate aqueous emulsion of embodiment 3 2%
Metrafenone 1%, 2-cyano-3-amino-3-phenylancryic acetate 1%, trimethylbenzene (solvent) 5%, solvent naphtha S-150 (solvents) 10%, nonyl phenol gather
Oxygen ethene ether phosphate (emulsifying agent) 15%, epoxidized linseed oil (stabilizer) 3%, glycerine (antifreezing agent) 1.5%, C10-20Saturation
Fatty acid compound (defoamer) 0.2%, Sodium Benzoate (preservative) 0.5%, cellulose ether (thickener) 1.5%, go from
Sub- water supplies 100%.Above-mentioned material is mixed in proportion, Jing after high shear agitation is uniform, you can 2% metrafenone is obtained
2-cyano-3-amino-3-phenylancryic acetate aqueous emulsion.
The metrafenone 2-cyano-3-amino-3-phenylancryic acetate microemulsion of example IV 16%
The metrafenone 1%, (emulsification of 2-cyano-3-amino-3-phenylancryic acetate 15%, cyclohexanone (solvent) 8%, dimethylbenzene (solvent) 5%, agriculture breast 2201#
Agent) 10%, methyl alcohol (assistant for emulsifying agent) 3%, epoxidized linseed oil (stabilizer) 3%, glycerine (antifreezing agent) 2%, silicone oil (froth breaking
Agent) 0.2%, deionized water supplies 100%.Above-mentioned material is mixed in proportion, Jing after high shear agitation is uniform, you can be obtained
16% metrafenone 2-cyano-3-amino-3-phenylancryic acetate microemulsion.
5 62% metrafenone 2-cyano-3-amino-3-phenylancryic acetate water dispersible granules of embodiment
Metrafenone 2%, 2-cyano-3-amino-3-phenylancryic acetate 60%, neopelex (wetting agent) 7%, polyoxyethylene polyoxypropylene base
Ether block copolymers (dispersant) 10%, polyvinylpyrrolidone (disintegrant) 5%, kaolin (filler) supply 100%.Will be upper
State material to mix in proportion, Jing after air-flow crushing is well mixed, mediates granulation, being dried screening, you can 62% metrafenone is obtained
2-cyano-3-amino-3-phenylancryic acetate water dispersible granules.
6 5% metrafenone 2-cyano-3-amino-3-phenylancryic acetate ultra low volume liquids of embodiment
Metrafenone 1%, 2-cyano-3-amino-3-phenylancryic acetate 4%, trimethylbenzene (solvent) 5%, DMAC N,N' dimethyl acetamide (solvent) 15%, fat
(poisoning subtracts alcohol APEO (surfactant) 8%, calcium dodecyl benzene sulfonate (surfactant) 5%, brassin lactones
Light diaphoretic prescription) 0.02%, fast penetrant T (bleeding agent) 2%, methyl oleate complements to 100%.Above-mentioned material is mixed in proportion,
After stirring, you can 5% metrafenone 2-cyano-3-amino-3-phenylancryic acetate ultra low volume liquids are obtained.
(2) indoor biological determination of activity embodiment
1st, metrafenone and 2-cyano-3-amino-3-phenylancryic acetate compounding are tested to the Toxicity Determination of wheat powdery mildew pathogen
Test method：With reference to《Farm-chemical indoor determination test rule NY/T1156.4-2006》, using pot-culture method.
Statistical analysis is carried out with DPS statistical analysis softwares, the EC of each medicament is calculated50, and mixture is calculated according to the abundant methods of Sun Yun
Co-toxicity coefficient (CTC values), co-toxicity coefficient (CTC) >=120 shows as synergistic effect；Co-toxicity coefficient (CTC)≤80 shows as short of money
Anti- effect；80 ＜ co-toxicity coefficients (CTC) ＜ 120 show as summation action.
The Toxicity Determination of 1 metrafenone of table and 2-cyano-3-amino-3-phenylancryic acetate compounding to wheat powdery mildew pathogen
| Medicament title and proportioning (weight ratio) | EC50(mg/L) | ATI | TTI | CTC |
| Metrafenone | 0.67 | 100.00 | ||
| 2-cyano-3-amino-3-phenylancryic acetate | 1.33 | 50.38 | ||
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (20:1) | 0.39 | 171.79 | 97.64 | 175.94 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (15:1) | 0.35 | 191.43 | 96.90 | 197.55 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (10:1) | 0.31 | 216.13 | 95.49 | 226.34 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (7:1) | 0.28 | 239.29 | 93.80 | 255.11 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (4:1) | 0.26 | 257.69 | 90.08 | 286.07 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:1) | 0.29 | 231.03 | 75.19 | 307.26 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:4) | 0.32 | 209.38 | 60.30 | 347.23 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:7) | 0.36 | 186.11 | 56.58 | 328.93 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:10) | 0.44 | 152.27 | 54.89 | 277.41 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:15) | 0.51 | 131.37 | 53.48 | 245.64 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:20) | 0.62 | 108.06 | 52.74 | 204.89 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:30) | 0.76 | 88.16 | 51.98 | 169.60 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:40) | 0.95 | 70.53 | 51.59 | 136.71 |
As it can be seen from table 1 metrafenone and 2-cyano-3-amino-3-phenylancryic acetate are 20:1～1:It is when compounding in the range of 40 (by weight), malicious altogether
Coefficient (CTC) is all higher than 120, illustrates to show synergistic function to wheat powdery mildew pathogen；Especially 10:1～1:
When compounding in the range of 20 (by weight), synergistic function is more significantly, and co-toxicity coefficient (CTC) is more than 200；Particularly
With 1:4 (by weight) compounding, synergistic function are the most notable, and co-toxicity coefficient (CTC) is maximum, is 347.23.It can be seen that, metrafenone
With 2-cyano-3-amino-3-phenylancryic acetate compounding with reasonability and feasibility.
2nd, metrafenone and 2-cyano-3-amino-3-phenylancryic acetate compounding are tested to the Toxicity Determination of wheat scab pathogen
Test method：With reference to《Farm-chemical indoor determination test rule NY/T1156.2-2006》, using Plating.
Statistical analysis is carried out with DPS statistical analysis softwares, the EC of each medicament is calculated50, and mixture is calculated according to the abundant methods of Sun Yun
Co-toxicity coefficient (CTC values), co-toxicity coefficient (CTC) >=120 shows as synergistic effect；Co-toxicity coefficient (CTC)≤80 shows as short of money
Anti- effect；80 ＜ co-toxicity coefficients (CTC) ＜ 120 show as summation action.
The Toxicity Determination of 2 metrafenone of table and 2-cyano-3-amino-3-phenylancryic acetate compounding to wheat scab pathogen
| Medicament title and proportioning (weight ratio) | EC50(mg/L) | ATI | TTI | CTC |
| Metrafenone | 1.98 | 100.00 | ||
| 2-cyano-3-amino-3-phenylancryic acetate | 1.07 | 185.05 | ||
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (20:1) | 1.14 | 173.68 | 104.05 | 166.92 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (15:1) | 0.99 | 200.00 | 105.32 | 189.90 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (10:1) | 0.83 | 238.55 | 107.73 | 221.43 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (7:1) | 0.76 | 260.53 | 110.63 | 235.50 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (4:1) | 0.67 | 295.52 | 117.01 | 252.56 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:1) | 0.48 | 412.50 | 142.53 | 289.41 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:4) | 0.39 | 507.69 | 168.04 | 302.12 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:7) | 0.42 | 471.43 | 174.42 | 270.28 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:10) | 0.45 | 440.00 | 177.32 | 248.14 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:15) | 0.49 | 404.08 | 179.73 | 224.83 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:20) | 0.52 | 380.77 | 181.00 | 210.37 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:30) | 0.61 | 324.59 | 182.31 | 178.04 |
| Metrafenone：2-cyano-3-amino-3-phenylancryic acetate (1:40) | 0.74 | 267.57 | 182.98 | 146.23 |
From table 2 it can be seen that metrafenone and 2-cyano-3-amino-3-phenylancryic acetate are 20:1～1:It is when compounding in the range of 40 (by weight), malicious altogether
Coefficient (CTC) is all higher than 120, illustrates to show synergistic function to wheat scab pathogen；Especially 10:1～1:
When compounding in the range of 20 (by weight), synergistic function is more significantly, and co-toxicity coefficient (CTC) is more than 200；Particularly
With 1:4 (by weight) compounding, synergistic function are the most notable, and co-toxicity coefficient (CTC) is maximum, is 302.12.It can be seen that, metrafenone
With 2-cyano-3-amino-3-phenylancryic acetate compounding with reasonability and feasibility.
(2) field efficacy embodiment
In wheat powdery mildew and head blight early stage dispenser, per 7d dispensers 1 time, dispenser 2 times altogether.The state of an illness is investigated before dispenser
Radix, after the 2nd dispenser, a situation arises for 14d investigation disease, counts disease index, calculates preventive effect.
3 metrafenone of table and 2-cyano-3-amino-3-phenylancryic acetate complex composition preparation are to wheat powdery mildew and the field control effectiveness test of head blight
From table 3 it can be seen that each metrafenone and 2-cyano-3-amino-3-phenylancryic acetate complex composition preparation are to wheat powdery mildew and head blight
Excellent prevention effect is shown, preventive effect is more than 80%, hence it is evident that be used alone higher than each single dose, wherein embodiment six (5%
Metrafenone 2-cyano-3-amino-3-phenylancryic acetate ultra low volume liquids) preventive effect of wheat powdery mildew and head blight is more projected, preventive effect up to 90% with
On.Do not find that each metrafenone and 2-cyano-3-amino-3-phenylancryic acetate complex composition preparation produce poisoning to wheat simultaneously during pilot survey.
In sum, a kind of complex composition containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate of the present invention, synergistic function
Significantly, compare each single dose and be used alone and expand fungicidal spectrum, improve preventive effect, can effectively prevent and treat powdery mildew on wheat and red mould
The multiple diseases such as disease, lasting period are long, to wheat safety, are worth the popularization and application in agricultural production.
Claims (7)
1. a kind of complex composition containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate, it is characterised in that：Effective active composition is by metrafenone and cyanogen
Alkene bacterium ester is constituted, and the weight ratio of metrafenone and 2-cyano-3-amino-3-phenylancryic acetate is 20:1～1:40.
2. the complex composition containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate according to claim 1, it is characterised in that：Metrafenone and cyanogen
The weight ratio of alkene bacterium ester is 10:1～1:20.
3. the complex composition containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate according to claim 2, it is characterised in that：Metrafenone and cyanogen
The weight ratio of alkene bacterium ester is 1:4.
4. the complex composition containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate according to claim 1, it is characterised in that：Complex composition
The gross weight percentage composition of middle metrafenone and 2-cyano-3-amino-3-phenylancryic acetate is 1%～80%.
5. the complex composition containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate according to claim 1, it is characterised in that the compounding group
The formulation of compound is aqueous suspension agent, oil-suspending agent, aqueous emulsion, microemulsion, water dispersible granules, ultra low volume liquids.
6. the complex composition containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate according to claim 5, it is characterised in that the compounding group
The formulation of compound is ultra low volume liquids.
7. powdery mildew and red mould of the complex composition containing metrafenone and 2-cyano-3-amino-3-phenylancryic acetate described in claim 1 on preventing and treating wheat
Application in disease.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106962345A (en) * | 2017-05-15 | 2017-07-21 | 南京农业大学 | A kind of bactericidal composition of 2-cyano-3-amino-3-phenylancryic acetate-containing and metrafenone |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002067679A1 (en) * | 2001-02-19 | 2002-09-06 | Basf Aktiengesellschaft | Fungicidal mixtures |
| CN1559210A (en) * | 2004-02-18 | 2005-01-05 | 江苏省农药研究所有限公司 | 2-cyano-3-amino-3-ethyl phenylacrylate used for prevention and control of plant disease and elimination of pests |
| CN103120170A (en) * | 2011-11-18 | 2013-05-29 | 深圳诺普信农化股份有限公司 | Bactericidal composition |
-
2016
- 2016-10-26 CN CN201610945674.8A patent/CN106538534A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002067679A1 (en) * | 2001-02-19 | 2002-09-06 | Basf Aktiengesellschaft | Fungicidal mixtures |
| CN1559210A (en) * | 2004-02-18 | 2005-01-05 | 江苏省农药研究所有限公司 | 2-cyano-3-amino-3-ethyl phenylacrylate used for prevention and control of plant disease and elimination of pests |
| CN103120170A (en) * | 2011-11-18 | 2013-05-29 | 深圳诺普信农化股份有限公司 | Bactericidal composition |
Non-Patent Citations (1)
| Title |
|---|
| 李恒奎 等: "氰烯菌酯防治小麦赤霉病及治理多菌灵抗药性研究", 《农药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106962345A (en) * | 2017-05-15 | 2017-07-21 | 南京农业大学 | A kind of bactericidal composition of 2-cyano-3-amino-3-phenylancryic acetate-containing and metrafenone |
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