CN105409964A - Germicidal composition containing fluopyram and proquinazid - Google Patents
Germicidal composition containing fluopyram and proquinazid Download PDFInfo
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- CN105409964A CN105409964A CN201510972737.4A CN201510972737A CN105409964A CN 105409964 A CN105409964 A CN 105409964A CN 201510972737 A CN201510972737 A CN 201510972737A CN 105409964 A CN105409964 A CN 105409964A
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- acid amides
- pyrrole bacterium
- fluorine pyrrole
- oxygen quinoline
- bacterium acid
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
Abstract
The present invention discloses a germicidal composition containing fluopyram and proquinazid, and applications thereof. Effective active ingredients consist of a first active ingredient fluopyram and a second active ingredient proquinazid. A weight ratio of the first active ingredient and the second active ingredient is from 1:50 to 50:1, preferably from 1:40 to 40:1. The composition can be formulated to agriculturally allowable dosage forms of missible oil, suspensions, wettable powders, water dispersible granules, water emulsions, micro emulsions, micro capsules, granules, and an aqueous agent. The composition disclosed by the present invention has reasonable components and a good germicidal effect. Moreover, the activity and germicidal effect of the composition are not a simple sum of each component activity. Compared with an existing single agent, in addition to having a significant germicidal effect, the composition of the present invention has a significant synergistic effect and high safety for crops. The composition of the present invention has a significant prevention and control effect on powdery mildew.
Description
Technical field
The present invention relates to a kind of bactericidal composition, be made up of the first active component fluorine pyrrole bacterium acid amides and the second active component third oxygen quinoline and auxiliary agent, belong to technical field of compounded pesticide.
Background technology
Fluorine pyrrole bacterium acid amides, English name is fluopyram, chemical name is N-{2-[the chloro-5-of 3-(trifluoromethyl)-2-pyridine radicals] ethyl]-α, α, the fluoro-0-toluamide of α-three, it is a kind of new benzamides series bactericidal agent, acting on the Complex II [i.e. succinate dehydrogenase (SDH) or succinic acid ubiquinone reductase (SQR)] on mitochondrial respiratory electron transport chain, suppressing mitochondrial respiratory by hindering the electro transfer of succinate dehydrogenase in respiratory chain.Be mainly used in broad leaf crop being prevented and treated the microbial disease of capsule.To the powdery mildew on the vegetables such as cucumber, custard squash, the multiple diseases such as target spot have favorable effect.
Third oxygen quinoline, English name proquinazid, chemical name is the iodo-2-propoxyl group of 6--3-propyl group quinazoline-4(3H) ketone, be mainly used in preventing and treating the diseases such as powdery mildew.Third oxygen quinoline can Antifungi spore germination, and prevents the formation of appresorium, and the formation of appresorium and growth are the prerequisites of fungal infection host plant.
Powdery mildew is widely distributed in China, particularly general to the harm of dicotyledon.After powdery mildew occurs, host's position growth of being injured is suppressed, moves back green flavescence gradually, occurs that withered spot is dried-up to last full leaf, make plant early withered time serious.The disease later stage, in the mould layer of white powder shape be made up of mycelia and conidium, the cleistothecium that the much scattered black of normal appearance is granular, and survive the winter with this, the secondary spring carries out First aggression with ascospore.Powdery mildew is once occur, and quickly, crops Growing season is energy-conservation to be infected spread speed repeatedly.Powdery mildew makes the crop products such as China's wheat, cucumber, grape be subjected to extreme loss, and therefore, the generation preventing and treating powdery mildew is significant to agricultural production.
Along with the passing of service time and the continuous increase of usage amount, it is a kind of inevitable that pathogen produces resistance to fluorine pyrrole bacterium acid amides and the third oxygen quinoline.Occur and expanding prevention spectrum for slowing down resistance, bactericide is mixed to be very important.Applicant is through retrieval, fluorine pyrrole bacterium acid amides and the third oxygen quinoline mixture is not also had to prevent and treat the bibliographical information of powdery mildew at present, be further advanced by test to find, by fluorine pyrrole bacterium acid amides different for the mechanism of action and the third oxygen quinoline composite, tool has an unexpected effect, and not only synergistic effect is remarkable, can also significantly improve the control efficiency to powdery mildew, reduce dosage, reduce cost accounting, to crop safety.
Summary of the invention
The object of the present invention is to provide a kind of component reasonable, synergistic effect is remarkable, and bactericidal effect is good, and drug cost is low, to the agricultural bactericidal composition of crop safety.
Another object of the present invention is to the bactericidal composition preparation formulation that containing fluopyram and the third oxygen quinoline are provided.
Another object of the present invention is to provide the application of above-mentioned composition on control crop powdery mildew.
In order to overcome the defect of existing unitary agent, technical scheme of the present invention solves like this:
A) the first active component fluorine pyrrole bacterium acid amides;
B) the second active component third oxygen quinoline;
The weight ratio of the first active component and the second active component is 1:50 ~ 50:1, is preferably 1:40 ~ 40:1.
The content sum of the first active component and the second active component is 1% ~ 80% of described composition total weight, is preferably 1% ~ 50%.
A kind of bactericidal composition containing fluorine pyrrole bacterium acid amides and the third oxygen quinoline of the present invention, the preparation formulation can prepared according to the method that those skilled in the art of the present technique are known is missible oil, suspending agent, wetting powder, water dispersible granules, aqueous emulsion, microemulsion, microcapsule formulations, granule, aqua.
To missible oil, spendable auxiliary agent has: emulsifier as calcium dodecyl benzene sulfonate (agriculture breast 500#), Nongru-700 #, agriculture breast 2201, this coil-60#, emulsifier T-60(common name: anhydrous sorbitol single-hard ester acid ester APEO), TX-10(common name: octyl phenol polyoxyethylene (10) ether), agriculture breast 1601#, one or more in agriculture breast 600#, the newborn 400# of agriculture etc.; Solvent is as one or more in dimethylbenzene, solvent naphtha (S-150, S-180, S-200), toluene, biodiesel, methylated vegetable oil, 1-METHYLPYRROLIDONE etc.; Cosolvent is as one or more in ethyl acetate, methyl alcohol, dimethyl formamide, cyclohexanone, acetone, MEK etc.; Stabilizing agent is as one or more in triphenyl phosphite, epoxychloropropane, aceticanhydride etc.
To suspending agent, spendable auxiliary agent has: dispersant as polycarboxylate, lignosulfonates, alkyl naphthalene formaldehyde condensate sulfonates, alkylphenol-polyethenoxy base ether phosphate, alkylphenol-polyethenoxy base ether sulfonate, phenethyl phenol polyethenoxy base ether phosphate, alkyl polyoxyethylene ether sulfonate, polyoxyethylene polyoxypropylene base ether block copolymers, pull open in powder, alkylpolyoxyethylene phosphate etc. one or more; Wetting agent is as one or more in alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, alkylnaphthalene sulfonate, alkyl phenol formaldehyde resin polyoxyethylene ether, in triphenoethyl benzene phenol polyoxyethylene polyoxypropylene block polymer etc.; Thickener is as one or more in xanthans, polyvinyl alcohol, bentonite, aluminium-magnesium silicate, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose etc.; Preservative is as one or more in formaldehyde, benzoic acid, Sodium Benzoate, potassium sorbate, isothiazolinone etc.; Defoamer as silicone oil, silicone compound, C10-20 saturated fat acid compounds, C8-10 aliphatic alcohols, hexanol, one or more in butanols, octanol etc.; Antifreezing agent is as one or more in ethylene glycol, propane diols, glycerine, polyethylene glycol, sorbierite, urea, inorganic salts etc.; Water is deionized water.
To wetting powder, spendable auxiliary agent has: dispersant is as one or more in polycarboxylate, lignosulfonates, polyoxyethylene polyoxypropylene base ether block copolymers, alkyl naphthalene formaldehyde condensate sulfonates, alkylphenol-polyethenoxy base ether phosphate, aliphatic alcohol polyoxyvinethene phosphate, alkylphenol-polyethenoxy base ether sulfonate etc.; Wetting agent is as one or more in alkyl sulfate, alkylsulfonate, alkylnaphthalene sulfonate etc.; Filler is as one or more in ammonium sulfate, urea, sucrose, glucose, diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay etc.
For water dispersible granules, spendable auxiliary agent has: dispersant is as one or more in polycarboxylate (TERSPERSE2700, T36, GY-D06 etc.), lignosulfonates, alkylnaphthalene sulfonate etc.; Wetting agent is as one or more in alkyl sulfate, alkylsulfonate, naphthalene sulfonate etc.; Disintegrant is as one or more in ammonium sulfate, sodium sulphate, polyvinylpyrrolidone, starch and derivative, bentonite etc.; Binding agent is as one or more in starch, glucose, polyvinyl alcohol, polyethylene glycol, sodium carboxymethylcellulose, sucrose etc.; Filler is as one or more in diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay etc.
To aqueous emulsion, spendable auxiliary agent has: emulsifier is as Nonyl pheno (EO=10) ether phosphate, triphenoethyl benzene phenol polyethenoxy ether phosphate, Nongru-700 #(alkyl phenol formaldehyde resin polyoxyethylene ether), agriculture breast 2201#, this dish-60#(Span60), Tween-60 #(polyoxyethylene sorbitan stearate), TX-10(octyl phenol polyoxyethylene (10) ether), agriculture breast 1601(triphenoethyl benzene phenol polyoxyethylene polyoxypropylene block polymer), one or more in agriculture breast 600#, agriculture breast 400# etc.; Solvent is as one or more in dimethylbenzene, toluene, cyclohexanone, solvent naphtha (trade mark: S-150, S-180, S-200) etc.; Stabilizing agent is as one or more in triphenyl phosphite, epoxychloropropane, epoxy soybean wet goods; Antifreezing agent is if ethylene glycol, propane diols, glycerine, urea, inorganic salts are as one or more in sodium chloride etc.; Thickener is as one or more in xanthans, polyvinyl alcohol, bentonite, aluminium-magnesium silicate etc.; Preservative is as one or more in formaldehyde, benzoic acid, Sodium Benzoate etc., and water is deionized water.
To microemulsion, spendable auxiliary agent has: emulsifier is as agriculture breast 500#(calcium dodecyl benzene sulfonate), Nongru-700 #, agriculture breast 2201, this dish-60#, polysorbate60-#, TX-10, agriculture breast 1601(phenethyl phenol polyoxyethylene poly-oxygen propylene aether), one or more in agriculture breast 600#, agriculture breast 400# etc.; Assistant for emulsifying agent is as one or more in methyl alcohol, isopropyl alcohol, n-butanol, ethanol etc.; Solvent is as one or more in cyclohexanone, 1-METHYLPYRROLIDONE, dimethylbenzene, toluene, solvent naphtha (trade mark: S-150, S-180, S-200) etc.; Stabilizing agent is as one or more in triphenyl phosphite, epoxychloropropane etc.; Water is deionized water.
To microcapsule formulations, spendable auxiliary agent has: emulsifying dispersant is as Nonyl pheno (EO=10) ether phosphate, triphenoethyl benzene phenol polyethenoxy ether phosphate, Nongru-700 #(common name: alkyl phenol formaldehyde resin polyoxyethylene ether), agriculture breast 2201#, this dish-60#(common name: Span60), Tween-60 #(common name: polyoxyethylene sorbitan stearate), TX-10(common name: octyl phenol polyoxyethylene (10) ether), agriculture breast 1601(common name: triphenoethyl benzene phenol polyoxyethylene polyoxypropylene block polymer), agriculture breast 600#, one or more in agriculture breast 400# etc., antifreezing agent is if ethylene glycol, propane diols, glycerine, urea, inorganic salts are as one or more in sodium chloride etc., thickener is as one or more in white carbon, polyvinyl alcohol, bentonite, aluminium-magnesium silicate etc., defoamer is as one or more in silicone oil, silicone compound, C10-20 saturated fat acid compounds, C8-10 aliphatic alcohols, hexanol, butanols, octanol etc., water is deionized water.
To granule, spendable auxiliary agent has: carrier is as one or more in clay, kaolin, talcum, calcium carbonate, corn starch, alumina silicate etc.; Dispersant is as one or more in polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate etc.; Wetting agent is as one or more in alkyl sulfate, alkylsulfonate, naphthalene sulfonate etc.; Adhesive is as one or more in polyvinyl alcohol, dextrin, polyvinylpyrrolidone etc.
To aqua, spendable auxiliary agent has: emulsifier is as one or more in calcium dodecyl benzene sulfonate, alkyl phenol formaldehyde resin polyoxyethylene ether, agriculture breast 2201#, sorbitan monostearate, sorbitan monostearate APEO, octyl phenol polyoxyethylene (10) ether, fatty alcohol-polyoxyethylene ether, phenethyl phenol polyoxyethylene poly-oxygen propylene aether, agriculture breast 600#, agriculture breast 400#, dodecyl benzyl dimethyl ammonium chloride etc.; Water is deionized water.
Instant component is reasonable, and treatment adds protective effect, and bactericidal effect is good, and drug cost is low, and its activity and bactericidal effect are not the simple superposition of each composition activity, but has significant synergistic effect, good to crop safety, meets the security requirement of pesticidal preparations.The present invention has excellent control efficiency to crop powdery mildew.
Embodiment
Illustrate whether fluorine pyrrole bacterium acid amides and the third oxygen quinoline mixture have synergistic effect to powdery mildew of cucumber below by Toxicity Determination.
In order to prevent and treat the powdery mildew of cucumber in agricultural production, we have carried out mutual composite synergy research with fluorine pyrrole bacterium acid amides and the third oxygen quinoline, and concrete grammar is as follows.
Subjects be cucumber powdery mildew's pathogen (
sphaerothecafuliginea).Former medicine is mixed with the test medicine of needs, test method is with reference to " farm-chemical indoor determination test rule bactericide the 6th part: the synergy of mixture measures " and " farm-chemical indoor determination test rule bactericide the 11st part: control cucurbits powdery mildew test pot-culture method ".
First single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients (on the basis of preliminary experiment, bacteriostasis rate sets by geometric progression in the scope of 5% ~ 90%).If blank, repeat 4 times.Adopt pot-culture method, liquid is evenly sprayed in blade face, for subsequent use after liquid natural air drying.Using spore suspension spray inoculation, natural air drying, then move to thermostatic chamber, is under the condition of 20 ~ 24 DEG C in temperature, cultivates 7d ~ 10d.When the sick leaf rate of blank reaches more than 80%, classification investigation manages incidence everywhere, often processes and at least investigates 30 leaves.Grade scale is:
0 grade: anosis;
1 grade: lesion area accounts for less than 5% of whole leaf area;
3 grades: lesion area accounts for 5% ~ 15% of whole leaf area;
5 grades: lesion area accounts for 15% ~ 25% of whole leaf area;
7 grades: lesion area accounts for 25% ~ 50% of whole leaf area;
9 grades: lesion area accounts for 50% ~ 75% of whole leaf area;
11 grades: lesion area accounts for more than 75% of whole leaf area;
According to survey data, calculate disease index and the control efficiency of each process.By the linear regression analysis between preventive effect probability value and the logarithm value of series concentration, obtain the EC50 value of each medicament.
Calculate the co-toxicity coefficient (CTC) of mixture by the abundant method of Sun Yun, evaluate the activity of reagent agent to germ with this.The co-toxicity coefficient (CTC) >=120 of complex preparation shows as synergistic effect; CTC≤80 show as antagonism; 80 < CTC < 120 show as summation action.
Table 1 fluorine pyrrole bacterium acid amides and the Toxicity Determination of the third oxygen quinoline combination to powdery mildew of cucumber
Toxicity Determination result shows: fluorine pyrrole bacterium acid amides and the third oxygen quinoline are that 1:50 ~ 50:1 is mixed with weight ratio has good virulence to powdery mildew of cucumber, and weight ratio is that 1:40 ~ 40:1 synergistic effect is remarkable.
In order to better the present invention is described, be described further content of the present invention below in conjunction with embodiment, the percentage in formula is all weight percentage.
Example of formulations 1
Take 15% fluorine pyrrole bacterium acid amides, the 25% the third oxygen quinoline, 3% Nongru-700 #, 5% agriculture breast 1601#, 3% this dish-60#, 2% acetone, 2% triphenyl phosphite, toluene adds to 100% weight portion.Above-mentioned raw materials is through mixing, and stirring and dissolving is obtained 40% fluorine pyrrole bacterium acid amides third oxygen quinoline missible oil completely afterwards.
Example of formulations 2
Take 20% fluorine pyrrole bacterium acid amides, the 10% the third oxygen quinoline, 3% agriculture breast 500#, 4% Nongru-700 #, 2% agriculture breast 1601#, 2% dimethyl formamide, 2% epoxychloropropane, biodiesel adds to 100% weight portion.Above-mentioned raw materials is through mixing, and stirring and dissolving is obtained 30% fluorine pyrrole bacterium acid amides third oxygen quinoline missible oil completely afterwards.
Example of formulations 3
Take 30% fluorine pyrrole bacterium acid amides, the 5% the third oxygen quinoline, 5% agriculture breast 1601#, 5% agriculture breast 2201,2% cyclohexanone, 2% epoxychloropropane, dimethylbenzene adds to 100% weight portion.Above-mentioned raw materials is through mixing, and stirring and dissolving is obtained 35% fluorine pyrrole bacterium acid amides third oxygen quinoline missible oil completely afterwards.
Example of formulations 4
Take 40% fluorine pyrrole bacterium acid amides, the 20% the third oxygen quinoline, 5% polycarboxylate, 4% phenethyl phenol polyethenoxy base ether phosphate, 5% sodium alkyl sulfate, 0.5% carboxymethyl cellulose, 3% sorbierite, 0.2% formaldehyde, 1% butanols, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear dispersion 30min, with sand mill sand milling to particle diameter D
90obtained 60% fluorine pyrrole bacterium acid amides third oxygen quinoline suspending agent after being less than 10 μm.
Example of formulations 5
Take 50% fluorine pyrrole bacterium acid amides, the 5% the third oxygen quinoline, 5% sodium lignin sulfonate, 4% sodium naphthalene sulfonate, 6% sodium alkyl sulfate, 0.4% aluminium-magnesium silicate, 0.1% bentonite, 5% propane diols, 0.1% Sodium Benzoate, 1% hexanols, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear dispersion 30min, with sand mill sand milling to particle diameter D
90obtained 55% fluorine pyrrole bacterium acid amides third oxygen quinoline suspending agent after being less than 10 μm.
Example of formulations 6
Take 45% fluorine pyrrole bacterium acid amides, the 10% the third oxygen quinoline, 4% alkyl naphthalene formaldehyde condensation product sodium sulfonate, 3% phenethyl phenol polyethenoxy base ether phosphate, 5% sodium alkyl sulfate, 0.5% carboxyethyl cellulose, 3% polyethylene glycol, 0.2% potassium sorbate, 2% octanols, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear dispersion 30min, with sand mill sand milling to particle diameter D
90obtained 55% fluorine pyrrole bacterium acid amides third oxygen quinoline suspending agent after being less than 10 μm.
Example of formulations 7
Take 25% fluorine pyrrole bacterium acid amides, the 15% the third oxygen quinoline, 3% calcium lignosulfonate, 5% alkylnaphthalene sulfonate formaldehyde condensation products, 2% lauryl sodium sulfate, diatomite fills up the weight portion to 100%.Above-mentioned raw materials is prepared into 40% fluorine pyrrole bacterium acid amides third oxygen quinoline wetting powder through mixing, ultra micro air-flow crushing, hybrid technique step.
Example of formulations 8
Take 35% fluorine pyrrole bacterium acid amides, the 5% the third oxygen quinoline, 3% alkylphenol-polyethenoxy base ether phosphate, 64% alkylnaphthalene sulfonate formaldehyde condensation products, 2% sodium alkyl sulfonates, talcum powder fills up the weight portion to 100%.Above-mentioned raw materials is prepared into 40% fluorine pyrrole bacterium acid amides third oxygen quinoline wetting powder through mixing, ultra micro air-flow crushing, hybrid technique step.
Example of formulations 9
Take 30% fluorine pyrrole bacterium acid amides, the 50% the third oxygen quinoline, 5% polyoxyethylene polyoxypropylene base ether block copolymers, 4% sodium lignin sulfonate, 4% Negels, fine particle calcium carbonate fills up the weight portion to 100%.Above-mentioned raw materials is prepared into 80% fluorine pyrrole bacterium acid amides third oxygen quinoline wetting powder through mixing, ultra micro air-flow crushing, hybrid technique step.
Example of formulations 10
Take 30% fluorine pyrrole bacterium acid amides, the 40% the third oxygen quinoline, 4% polycarboxylate T36,3% sodium lignin sulfonate, 1% Nekal BX (nekal), 1%K-12(lauryl sodium sulfate), 1% polyethylene glycol, 2% starch, attapulgite adds to 100% weight portion.Namely the method for above-mentioned raw materials frequent regulation water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step produce 70% fluorine pyrrole bacterium acid amides third oxygen quinoline water dispersible granules.
Example of formulations 11
Take 25% fluorine pyrrole bacterium acid amides, the 15% the third oxygen quinoline, 5% polycarboxylate GY-D06,3% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 2% nekal, 3% lauryl sodium sulfate, potter's clay adds to 100% weight portion.Namely the method for above-mentioned raw materials frequent regulation water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step produce 40% fluorine pyrrole bacterium acid amides third oxygen quinoline water dispersible granules.
Example of formulations 12
Take 20% fluorine pyrrole bacterium acid amides, the 25% the third oxygen quinoline, 5% sodium lignin sulfonate, 4% Negel, 2% Nekal BX (nekal), 2% lauryl sodium sulfate, fine particle calcium carbonate adds to 100% weight portion.Namely the method for above-mentioned raw materials frequent regulation water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step produce 45% fluorine pyrrole bacterium acid amides third oxygen quinoline water dispersible granules.
Example of formulations 13
Take 30% fluorine pyrrole bacterium acid amides, the 10% the third oxygen quinoline, 4% agriculture breast 2201#, 2% Nonyl pheno (EO=10) ether phosphate, 4% Tween-60 #, 5% propane diols, 8% solvent naphtha S-180,5% cyclohexanone, 0.2% bentonite, 0.5% Sodium Benzoate, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear emulsification obtains 40% fluorine pyrrole bacterium acid amides third oxygen quinoline aqueous emulsion.
Example of formulations 14
Take 10% fluorine pyrrole bacterium acid amides, the 35% the third oxygen quinoline, 5% agriculture breast 1601,3% Nonyl pheno (EO=10) ether phosphate, 5% triphenoethyl benzene phenol polyethenoxy ether phosphate, 2% this dish-60#, 1% epoxychloropropane, 2% glycerine, 5% dimethylbenzene, 0.2% aluminium-magnesium silicate, 0.5% Sodium Benzoate, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear emulsification obtains 45% fluorine pyrrole bacterium acid amides third oxygen quinoline aqueous emulsion.
Example of formulations 15
Take 20% fluorine pyrrole bacterium acid amides, the 30% the third oxygen quinoline, 7% agriculture breast 400#, 3% triphenoethyl benzene phenol polyethenoxy ether phosphate, 2% this dish-60#, 1% epoxychloropropane, 2% sodium chloride, 3% cyclohexanone, 0.2% polyvinyl alcohol, 0.5% benzoic acid, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear emulsification obtains 50% fluorine pyrrole bacterium acid amides third oxygen quinoline aqueous emulsion.
Example of formulations 16
Take 10% fluorine pyrrole bacterium acid amides, the 15% the third oxygen quinoline, 5% Nongru-700 #, 6% agriculture breast 1601#, 15% dimethylbenzene, 5% toluene, 3% ethanol, through dissolving completely and mixing, deionized water adds to 100% weight portion, obtained 25% fluorine pyrrole bacterium acid amides third oxygen quinoline microemulsion after stirring.
Example of formulations 17
Take 15% fluorine pyrrole bacterium acid amides, the 15% the third oxygen quinoline, 4% agriculture breast 400#, 5% polysorbate60-#, 25% cyclohexanone, 4% dimethylbenzene, 5% n-butanol, through dissolving completely and mixing, deionized water adds to 100% weight portion, obtained 30% fluorine pyrrole bacterium acid amides third oxygen quinoline microemulsion after stirring.
Example of formulations 18
Take 25% fluorine pyrrole bacterium acid amides, the 5% the third oxygen quinoline, 5% agriculture breast 2201,6% agriculture breast 400#, 25% solvent naphtha S-180,5% dimethylbenzene, 5% methyl alcohol, through dissolving completely and mixing, deionized water adds to 100% weight portion, obtained 30% fluorine pyrrole bacterium acid amides third oxygen quinoline microemulsion after stirring.
Example of formulations 19
Take 3% fluorine pyrrole bacterium acid amides, the 2% the third oxygen quinoline, 3% glycerine, 6% Tween-60 #, 1% aluminium-magnesium silicate, 2% hexanols, deionized water fills up the weight portion to 100%.Above-mentioned raw materials is obtained 5% fluorine pyrrole bacterium acid amides third oxygen quinoline microcapsule formulations after mix and blend, polymerisation.
Example of formulations 20
Take 1% fluorine pyrrole bacterium acid amides, the 4% the third oxygen quinoline, 5% propane diols, 8% this dish-60#, 1% white carbon, 1.5% octanol, deionized water fills up the weight portion to 100%.Above-mentioned raw materials is obtained 5% fluorine pyrrole bacterium acid amides third oxygen quinoline microcapsule formulations after mix and blend, polymerisation.
Example of formulations 21
Take 2% fluorine pyrrole bacterium acid amides, the 2% the third oxygen quinoline, 5% glycerine, 7% agriculture breast 600#, 1% white carbon, 2% butanols, deionized water fills up the weight portion to 100%.Above-mentioned raw materials is obtained 4% fluorine pyrrole bacterium acid amides third oxygen quinoline microcapsule formulations after mix and blend, polymerisation.
Example of formulations 22
Take 3% fluorine pyrrole bacterium acid amides, the 2% the third oxygen quinoline, 5% sodium lignin sulfonate, 5% sodium naphthalene sulfonate, 3% polyvinylpyrrolidones, calcium carbonate adds to 100% weight portion.Above-mentioned raw materials mixes in mixed cylinder, through extruding, granulation, drying, and through the obtained 5% fluorine pyrrole bacterium acid amides third oxygen quinoline granule of screening step.
Example of formulations 23
Take 0.5% fluorine pyrrole bacterium acid amides, the 0.5% the third oxygen quinoline, 4% Negel, 5% sodium alkyl sulfonate, 3% dextrin, corn starch adds to 100% weight portion.Above-mentioned raw materials mixes in mixed cylinder, through extruding, granulation, drying, and through the obtained 1% fluorine pyrrole bacterium acid amides third oxygen quinoline granule of screening step.
Example of formulations 24
Take 2% fluorine pyrrole bacterium acid amides, the 1% the third oxygen quinoline, 5% sodium lignin sulfonate, 4% sodium naphthalene sulfonate, 2% polyvinyl alcohol, calcium carbonate adds to 100% weight portion.Above-mentioned raw materials mixes in mixed cylinder, through extruding, granulation, drying, and through the obtained 3% fluorine pyrrole bacterium acid amides third oxygen quinoline granule of screening step.
Example of formulations 25
Take 5% fluorine pyrrole bacterium acid amides, the 10% the third oxygen quinoline, 5% alkyl phenol formaldehyde resin polyoxyethylene ether, 2% agriculture breast 2201#, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and stirring and dissolving is obtained 15% fluorine pyrrole bacterium acid amides third oxygen quinoline aqua completely afterwards.
Example of formulations 26
Take 25% fluorine pyrrole bacterium acid amides, the 15% the third oxygen quinoline, 3% fatty alcohol-polyoxyethylene ether, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and stirring and dissolving is obtained 40% fluorine pyrrole bacterium acid amides third oxygen quinoline aqua completely afterwards.
Example of formulations 27
Take 30% fluorine pyrrole bacterium acid amides, the 5% the third oxygen quinoline, 5% agriculture breast 400#, 3% agriculture breast 2201#, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and stirring and dissolving is obtained 35% fluorine pyrrole bacterium acid amides third oxygen quinoline aqua completely afterwards.
biological Examples 1: prevent and treat powdery mildew of cucumber field trial.
Within 2015, carry out example of formulations 3(35% fluorine pyrrole bacterium acid amides third oxygen quinoline missible oil in Shouguang City of Shandong Province), example of formulations 6(55% fluorine pyrrole bacterium acid amides third oxygen quinoline suspending agent), example of formulations 7(40% fluorine pyrrole bacterium acid amides third oxygen quinoline wetting powder), example of formulations 11(40% fluorine pyrrole bacterium acid amides third oxygen quinoline water dispersible granules), example of formulations 14(45% fluorine pyrrole bacterium acid amides third oxygen quinoline aqueous emulsion), example of formulations 17(30% fluorine pyrrole bacterium acid amides third oxygen quinoline microemulsion), example of formulations 20(5% fluorine pyrrole bacterium acid amides third oxygen quinoline microcapsule formulations), example of formulations 24(3% fluorine pyrrole bacterium acid amides third oxygen quinoline granule), example of formulations 25(15% fluorine pyrrole bacterium acid amides third oxygen quinoline aqua) prevent and treat powdery mildew of cucumber field trial, demonstrate the control efficiency of this medicament to powdery mildew of cucumber and the safety to cucumber.Trial crops is cucumber, controlling object be powdery mildew of cucumber (
sphaerothecafuliginea).Test is located at Zhen Dong rice field village, rice field, Shouguang City, and experimental field physical features is smooth, and soil is loam, middle fertility, pH value 6.9, and duration of test rich water quality management is medium.Test medicine and dosage refer to table 2.Separately establish blank, often process 4 times and repeat, every community 30 ㎡, Gong48Ge community, random district group arranges.Adopt conventional spray-on process, mu dispenser liquid 45kg, is evenly sprayed at leave dual sides.
Investigation and statistical method: investigate state of an illness radix before dispenser, after last dispenser, 10 ~ 14d reinvestigates once, investigate 2 times altogether.Every community gets 4 points at random, and whole blades of often some investigation 2 strains, every sheet leaf accounts for the percentage classification record of leaf area according to scab.Stage division:
0 grade: without scab;
1 grade: lesion area accounts for less than 5% of whole leaf area;
3 grades: lesion area accounts for 6% ~ 10% of whole leaf area;
5 grades: lesion area accounts for 11% ~ 20% of whole leaf area;
7 grades: lesion area accounts for 21% ~ 40% of whole leaf area;
9 grades: lesion area accounts for more than 40% of whole leaf area.
Disease index=[∑ (the sick number of sheets × relative level numerical value at different levels)/(investigation total leaf number × 9)] × 100
Control efficiency (%)=[1-(before contrast dispenser after disease index × process dispenser disease index)/(to contrast after dispenser disease index before disease index × process dispenser] × 100
powdery mildew of cucumber field test results prevented and treated by table 2
Field test results shows, above 9 example of formulations have good control efficiency to powdery mildew of cucumber, spray 2 times by active ingredient 5g/ mu respectively, 94.37%, 93.53%, 94.47%, 93.89%, 94.75%, 95.21%, 93.35%, 94.19%, 95.07% is respectively to the preventive effect of 10 days after powdery mildew of cucumber the 2nd medicine, is obviously better than the preventive effect of 41.7% fluorine pyrrole bacterium amide suspending agents, the 20% the third oxygen quinoline missible oil 5g/ mus.By to significance of difference analysis in 10 days after medicine, difference reaches pole significance level (see table 2).
To the security survey of cucumber, within after spray medicine after the 1st day and medicine some days, observe, each test process occurs without poisoning phenomenon cucumber.
Except powdery mildew of cucumber, above-mentioned example of formulations is when active ingredient dosage is 5g/ mu, and also have synergistic effect to Leaf Spot Caused by Corynespora cassiicola on Cucumber, black spot, preventive effect reaches more than 90%.
Above embodiment explanation, 1:50 ~ 50:1 is composite by weight for first active component fluorine pyrrole bacterium acid amides and the second active component third oxygen quinoline, can be made into missible oil, suspending agent, wetting powder, water dispersible granules, aqueous emulsion, microemulsion, microcapsule formulations, granule, aqua formulation, significant control efficiency is had to vegetables powdery mildew, synergistic effect is obvious, dosage is few, control efficiency is high, and good to vegetable safety.
In sum, composition of the present invention is employing two kinds of active component compound schemes, its activity and bactericidal effect are not the simple superposition of each composition activity, compared with existing unitary agent, except there is significant bactericidal effect, more there is significant synergistic effect, good to crop safety, meet the security requirement of pesticidal preparations.
Claims (7)
1. one kind contains the bactericidal composition of fluorine pyrrole bacterium acid amides and the third oxygen quinoline, it is characterized in that, active ingredient is made up of the first active component fluorine pyrrole bacterium acid amides and the second active component third oxygen quinoline, and the weight ratio of the first active component and the second active component is 1:50 ~ 50:1.
2. contain the bactericidal composition of fluorine pyrrole bacterium acid amides and the third oxygen quinoline according to claim 1, it is characterized in that, the weight ratio of the first active component and the second active component is 1:40 ~ 40:1.
3. contain the bactericidal composition of fluorine pyrrole bacterium acid amides and the third oxygen quinoline according to claim 1, it is characterized in that, the content sum of the first active component and the second active component is 1% ~ 80% of described composition total weight.
4. contain the bactericidal composition of fluorine pyrrole bacterium acid amides and the third oxygen quinoline according to claim 1, it is characterized in that, the content sum of the first active component and the second active component is 1% ~ 50% of described composition total weight.
5. contain the bactericidal composition of fluorine pyrrole bacterium acid amides and the third oxygen quinoline according to claim 1, it is characterized in that described combination dosage form is for outstanding missible oil, suspending agent, wetting powder, water dispersible granules, aqueous emulsion, microemulsion, microcapsule formulations, granule, aqua.
6. the bactericidal composition according to claim 1 containing fluorine pyrrole bacterium acid amides and the third oxygen quinoline is preventing and treating the purposes in powdery mildew.
7. purposes according to claim 6, powdery mildew is powdery mildew of cucumber.
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Cited By (2)
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| CN115918646A (en) * | 2022-11-25 | 2023-04-07 | 惠州市银农科技股份有限公司 | Fluopyram-containing suspending agent and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107646856A (en) * | 2017-09-22 | 2018-02-02 | 陕西西大华特科技实业有限公司 | A kind of bactericidal composition containing benziothiazolinone and the third oxygen quinoline |
| CN115918646A (en) * | 2022-11-25 | 2023-04-07 | 惠州市银农科技股份有限公司 | Fluopyram-containing suspending agent and preparation method thereof |
| CN115918646B (en) * | 2022-11-25 | 2023-08-11 | 惠州市银农科技股份有限公司 | Fluopicolide-containing suspending agent and preparation method thereof |
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