CN108077270A - A kind of bactericidal composition containing fluopyram and fenhexamid - Google Patents
A kind of bactericidal composition containing fluopyram and fenhexamid Download PDFInfo
- Publication number
- CN108077270A CN108077270A CN201711341669.7A CN201711341669A CN108077270A CN 108077270 A CN108077270 A CN 108077270A CN 201711341669 A CN201711341669 A CN 201711341669A CN 108077270 A CN108077270 A CN 108077270A
- Authority
- CN
- China
- Prior art keywords
- fenhexamid
- fluopyram
- suspending agent
- agent
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
- A01N37/22—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof the nitrogen atom being directly attached to an aromatic ring system, e.g. anilides
- A01N37/24—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof the nitrogen atom being directly attached to an aromatic ring system, e.g. anilides containing at least one oxygen or sulfur atom being directly attached to the same aromatic ring system
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of containing fluopyram and the bactericidal composition of fenhexamid, effective active composition is made of the first active ingredient fluopyram and the second active ingredient fenhexamid, and the weight ratio of the first active ingredient and the second active ingredient is 1：80~60：1, it is preferably 1：60~40：1, it is most preferably 1：30~20：1.This composition can be configured to the wettable powder agriculturally allowed, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension suspending agent, dispersible oil-suspending agent, dry suspending agent dosage form.Instant component is reasonable, and bactericidal effect is good, and its activity and bactericidal effect are not the simple superposition of each component activity, compared with existing unitary agent, in addition to significant bactericidal effect, and have significant synergistic effect, good to crop safety.The present invention has significant control effect to crop gray mold, brown rot, powdery mildew, early blight, scab.
Description
Technical field
The present invention relates to a kind of bactericidal composition, by the first active ingredient fluopyram and the second active ingredient ring acyl bacterium
Amine and auxiliary agent composition, belong to technical field of compounded pesticide.
Background technology
Fluopyram, English name fluopyram, chemical name are N- { 2- [3- chloro- 5- (trifluoromethyl) -2- pyrroles
Piperidinyl] ethyl]-α, the fluoro- 0- toluamides of α, α-three are a kind of new benzamides series bactericidal agents, act on mitochondrial respiratory
Complex II [i.e. succinate dehydrogenase (succinatedehydrogenase, SDH) or succinic acid coenzyme on electron transport chain
Q reductases (succinate-coenzymeQreductase, SQR)], by the electronics for hindering succinate dehydrogenase in respiratory chain
It shifts and inhibits mitochondrial respiratory.It is mainly used for preventing the microbial disease of capsule on broad leaf crop.To vegetables such as cucumber, cucurbita pepos
On powdery mildew, the multiple diseases such as target spot have favorable effect.
Fenhexamid, English name fenhexamid, acid amide fungicides, with existing fungicide benzimidazole, dihydroxy acid imide
The no interactions resistances such as class, triazole type, aniline pyrimidine class, N- carbanilates can prevent various gray molds and relevant
Sclerotiniose, black spot etc..
Applicant is through retrieval, and there is presently no the texts of fluopyram and fenhexamid mixture prevention plant fungal disease
Report is offered, experiment is further advanced by and finds, the different fluopyram of the mechanism of action and fenhexamid are compounded, have and expect
Less than effect, there is good control effect to gray mold, brown rot, powdery mildew, early blight, scab, synergistic effect is bright
It is aobvious, dosage is reduced, cost accounting is reduced, to crop safety.
The content of the invention
It is an object of the invention to provide a kind of component is reasonable, synergistic effect is notable, and bactericidal effect is good, and drug cost is low,
To the agricultural bactericidal composition of crop safety.
Another object of the present invention is to provide the bactericidal composition preparation formulation of containing fluopyram and fenhexamid.
It is still another object of the present invention to provide above-mentioned composition in prevention crop gray mold, brown rot, powdery mildew, early epidemic
Application in disease, scab.
The defects of in order to overcome existing unitary agent, the technical scheme is that so solve：
A）First active ingredient fluopyram；
B）Second active ingredient fenhexamid；
The weight ratio of first active ingredient and the second active ingredient is 1：80~60：1, it is preferably 1：60~40：1, be most preferably
1：30~20：1.
The sum of content of first active ingredient and the second active ingredient is the 1%~60% of the composition total weight, preferably
For 1%~50%.
A kind of bactericidal composition containing fluopyram and fenhexamid of the present invention, according to those skilled in the art of the present technique
The preparation formulation that known method can be prepared is wettable powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, micro-
Emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent, dispersible oil-suspending agent, dry suspending agent.
To wettable powder, workable auxiliary agent has：Dispersant such as polycarboxylate, lignosulfonates, polyoxyethylene gather
Oxypropylene group ether block copolymers, alkyl naphthalene formaldehyde condensate sulfonates, alkylphenol-polyethenoxy base ether phosphate, poly alkyl alcohol
One or more in ethylene oxide ether phosphate, alkylphenol-polyethenoxy base ether sulfonate etc.；Wetting agent such as alkyl sulfate, alkane
One or more in base sulfonate, alkylnaphthalene sulfonate etc.；Filler such as ammonium sulfate, urea, sucrose, glucose, diatomite, height
One or more in ridge soil, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, clay etc..
To water dispersible granules, workable auxiliary agent has：Dispersant such as polycarboxylate（TERSPERSE2700、T36、GY-D06
Deng）, lignosulfonates, the one or more in alkylnaphthalene sulfonate etc.；Wetting agent for example alkyl sulfate, alkylsulfonate,
One or more in naphthalene sulfonate etc.；Disintegrant such as ammonium sulfate, sodium sulphate, polyvinylpyrrolidone, starch and its derivative,
One or more in bentonite etc.；Binding agent for example starch, glucose, polyvinyl alcohol, polyethylene glycol, sodium carboxymethylcellulose,
One or more in sucrose etc.；In filler such as diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, clay
One or more.
To suspending agent, workable auxiliary agent has：Dispersant such as polycarboxylate, lignosulfonates, alkyl naphthalene formaldehyde condensation
Object sulfonate, alkylphenol-polyethenoxy base ether phosphate, alkylphenol-polyethenoxy base ether sulfonate, phenethyl phenol polyoxyethylene groups
Ether phosphate, alkyl polyoxyethylene ether sulfonate, polyoxyethylene polyoxypropylene base ether block copolymers, pull open powder, dodecyl
One or more in polyoxyethylene ether phosphate etc.；Wetting agent such as alkylphenol-polyethenoxy base ether formaldehyde condensation products sulfate,
Phenethyl phenol polyoxyethylene groups ether phosphate, alkyl sulfate, alkylsulfonate, alkylnaphthalene sulfonate, alkylphenol-formaldehyde resin
One or more in polyoxyethylene ether, in triphenoethyl benzene phenol polyoxyethylene polyoxypropylene block polymer etc.；Thickener is such as
One in xanthans, polyvinyl alcohol, bentonite, aluminium-magnesium silicate, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose etc.
Kind is a variety of；One or more in preservative such as formaldehyde, benzoic acid, sodium benzoate, potassium sorbate, isothiazolinone；Disappear
Infusion such as silicone oil, silicone compound, C10-20 saturated fat acid compounds, C8-10 aliphatic alcohols, hexanol, butanol, octanol
One or more in；Antifreezing agent such as ethylene glycol, propylene glycol, glycerine, polyethylene glycol, sorbierite, urea, inorganic salts etc.
In one or more；Water is deionized water.
To suspension emulsion, workable auxiliary agent has：Emulsifier such as calcium dodecyl benzene sulfonate（Agriculture breast 500#）, Nongru-700 #,
Agriculture breast 2201, this disk -60#, emulsifier T-60（Common name：Anhydrous sorbitol single-hard ester acid ester polyoxyethylene ether）、TX-10（It is logical
With name：Octylphenol polyethylene ethylene oxide（10）Ether）, agriculture breast 1601#, agriculture breast 600#, the one or more in agriculture breast 400#；Dispersant is such as
It is one or more in polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate；Solvent such as repefral, adjacent benzene two
It is one or more in formic acid dibutyl ester, ethyl acetate, methyl benzoate；Antifoaming agent is as such as silicone oil, silicone compound, C10-20
One or more in saturated fat acids compound, C8-10 aliphatic alcohols, hexanol, butanol, octanol；Thickener such as white carbon,
It is one or more in polyvinyl alcohol, bentonite, aluminium-magnesium silicate；Antifreeze such as ethylene glycol, propylene glycol, glycerine, urea, inorganic salts
Such as one or more in sodium chloride；Water is deionized water.
To aqueous emulsion, workable auxiliary agent has：Emulsifier such as Nonyl pheno（EO=10）Ether phosphate, triphen second
Base phenol polyoxyethylene phosphonate, Nongru-700 #（Alkyl phenol formaldehyde resin polyoxyethylene ether）, agriculture breast 2201#, this disk -60#
（Span60）, Tween-60 #（Polyoxyethylene sorbitan stearate）、TX-10（Octyl phenol polyoxy second
Alkene（10）Ether）, agriculture breast 1601（Triphenoethyl benzene phenol polyoxyethylene polyoxypropylene block polymer）, agriculture breast 600#, agriculture breast 400#
One or more in；Solvent such as dimethylbenzene, toluene, cyclohexanone, solvent naphtha（The trade mark：S-150、S-180、S-200）In
One or more；One or more in stabilizer such as triphenyl phosphite, epoxychloropropane, epoxidized soybean oil；It is antifreeze
One or more in agent such as ethylene glycol, propylene glycol, glycerine, urea, inorganic salts such as sodium chloride；Thickener such as xanthans,
One or more in polyvinyl alcohol, bentonite, aluminium-magnesium silicate etc.；One in preservative such as formaldehyde, benzoic acid, sodium benzoate
Kind is a variety of, and water is deionized water.
To microemulsion, workable auxiliary agent has：Emulsifier such as agriculture breast 500#（Calcium dodecyl benzene sulfonate）, Nongru-700 #,
Agriculture breast 2201, this disk-60#, polysorbate60-#, TX-10, agriculture breast 1601（Phenethyl phenol polyoxyethylene poly-oxygen propylene aether）, agriculture breast
One or more in 600#, agriculture breast 400# etc.；One kind or more in assistant for emulsifying agent such as methanol, isopropanol, n-butanol, ethyl alcohol
Kind；Solvent such as cyclohexanone, N-Methyl pyrrolidone, dimethylbenzene, toluene, solvent naphtha（The trade mark：S-150、S-180、S-200）In
One or more；One or more in stabilizer such as triphenyl phosphite, epoxychloropropane；Water is deionized water.
To microcapsule suspending agent, workable auxiliary agent has：Macromolecule cyst material for example polyfunctional group acyl halide polyamines, gelatin,
It is one or more in Arabic gum, deformation lactoprotein, sodium alginate；Dispersant such as aliphatic alcohol polyethenoxy base ether, alkyl phenol gather
It is one or more in the phonetic formaldehyde condensation products sulfate of ethylene oxide, alkylbenzenesulfonate；Solvent such as aliphatic ester, linseed oil, oleic acid
It is one or more in methyl esters；Emulsifier such as benzyl dimethyl phenol polyoxyethyl ether, phenethyl phenol polyoxyethanyl polypropylene-base ether, ring
It is one or more in oxidative ethane-propylene oxide block copolymer；PH conditioning agents such as sodium hydroxide and hydrochloric acid, citric acid, sorbic acid
Middle one or more；It is a kind of or more in antifoaming agent such as C8-10 aliphatic alcohols, amide, organic silicon defoamer, hexanol, butanol, octanol
Kind；Water is deionized water.
To microcapsule suspension-suspendinagent agent, workable auxiliary agent has：Disintegrant such as bentonite, urea, ammonium sulfate, polyethylene pyrrole
One or more in pyrrolidone, glucose, sodium acid carbonate；Preservative such as formaldehyde, benzoic acid, sodium benzoate, potassium sorbate, different
One or more in thiazolinone etc.；Emulsifier such as fatty alcohol polyoxyethylene ether, aliphatic acid polyethenoxy ether, detergent alkylate
Sulfoacid calcium, alkylphenol polyoxyethylene ether, styrylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, sorbitol anhydride list are hard
One or more in resin acid ester, sorbitan monostearate polyoxyethylene ether, aliphatic acid polyethenoxy ether phosphate etc.；
Dispersant such as polycarboxylate, lignosulfonates, alkylphenol-polyethenoxy base ether formaldehyde condensation products sulfate（SOPA）, naphthalene and alkane
Base naphthalene formaldehyde condensate sulfonates class, EO-PO block polyethers class, alkylphenol-polyethenoxy base ether phosphate, alkyl phenol polyoxy second
One kind or more in alkene ether, polyoxyethylene carboxylate, aliphatic amine polyoxyethylene ether, glycerine fatty acid ester APEO etc.
Kind；Wetting agent such as lauryl sodium sulfate, neopelex, Nekal BX, moistening bleeding agent F, naphthalene sulphonate formaldehyde
One or more in condensation product etc.；One or more in antifreezing agent such as urea, ethylene glycol, propylene glycol, glycerine；Thickening
One kind in agent such as xanthans, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose, aluminium-magnesium silicate, polyvinyl alcohol or
It is a variety of；Antifoaming agent such as organic silicone oil, silicone compound, C10-20 saturated fat acid compounds, C8-10 fatty alcohols, ester ether
One or more in class etc..
To dispersible oil-suspending agent, workable auxiliary agent has：Dispersant such as polycarboxylate, lignosulfonates, alkylnaphthalene
Sulfonate（Dispersing agent NNO）、TERSPERSE2020（Huntsman Corporation of U.S. HUNTSMAN produces, alkyl naphthalene sulfonic acid salt）In
It is one or more；Emulsifier such as BY（Castor oil polyoxyethylene ether）Serial emulsifier（BY-110、BY-125、BY-140）, agriculture breast
700#（Common name：Alkyl phenol formaldehyde resin polyoxyethylene ether）, agriculture breast 2201, this disk -60#（Common name：Sorbitol anhydride list is stearic
Acid esters）, Tween-60 #（Common name：Sorbitan monostearate polyoxyethylene ether）, agriculture breast 1601#（Common name：Phenethyl
Phenol polyoxyethylene poly-oxygen propylene aether）、TERSPERSE4894（Huntsman Corporation of the U.S. produces）In one or more；Wetting
Agent such as alkylphenol-polyethenoxy base ether formaldehyde condensation products sulfate, alkylphenol polyoxyethylene ether phosphate, phenethyl phenol polyoxy second
Alkenyl ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, TERSPERSE2500（Huntsman Corporation of the U.S. produces）
Middle one or more；It is one or more in thickener such as white carbon, polyvinyl alcohol, bentonite, aluminium-magnesium silicate；Antifreezing agent such as second two
It is one or more in alcohol, propylene glycol, glycerine, urea, inorganic salts such as sodium chloride；Decentralized medium such as soybean oil, rapeseed oil, wheat
It is one or more in oil, methyl oleate, diesel oil, machine oil, mineral oil.
To dry suspending agent, workable auxiliary agent has：Dispersant such as lauryl sodium sulfate, polycarboxylate, acrylic acid homopolymerization
Oxygen sodium salt, dioctyl sodium sulphosuccinate, Teepol, neopelex, fatty acid polyethylene glycol ester, alkane acyl
Amido taurate, hydroxypropyl cellulose sodium, fatty alcohol polyoxyethylene ether, sodium naphthalene sulfonate, Negel, aliphatic acid sulphur alkane
One or more in base ester, lignosulfonates etc.；Wetting agent such as lauryl sodium sulfate, Negel, dodecane
In base benzene sulfonic acid sodium salt, sodium lignin sulfonate, Negel formaldehyde condensation products, alkylphenol-polyethenoxy base ether, pull open powder etc.
One or more；Disintegrant such as phosphate, sulfate, carbonate, urea, sodium chloride, bentonite, polyvinylpyrrolidone etc.
In one or more；Binding agent such as Arabic gum, carboxymethyl cellulose, polyvinyl alcohol, polyethylene glycol, polyvinylpyrrolidone
One or more in；Antifoaming agent such as silicone oil, silicone compound, C10-20 saturated fat acid compounds, C8-10 fat
One or more in alcohols, hexanol, butanol, octanol etc.；Carrier such as diatomite, precipitated calcium carbonate, tripoli, kaolin, hard charcoal
One or more in black, attapulgite etc..
Instant component is reasonable, and treatment plus protective effect, bactericidal effect is good, and drug cost is low, and its activity and sterilization effect
Fruit is not the simple superposition of each component activity, but has significant synergistic effect, good to crop safety, meets pesticidal preparations
Security requirement.The present invention has excellent control effect to crop powdery mildew.
Specific embodiment
The mixture synergy of graw mold of tomato is measured.
In order to prevent the graw mold of tomato in agricultural production, we with the progress of fluopyram and fenhexamid mutually
The synergy research of compounding, specific method are as follows.
Experiment is using graw mold of tomato（Botrytis cinerea）For test object.The experiment that active compound is configured to need
Single dose and each Mixed Pharmacy are set 5 various concentration gradients by medicament（On the basis of pilot study result, bacteriostasis rate is 5%
It is set in the range of~90% by geometric progression）.If clear water compares, it is repeated 4 times.Experiment will be cultivated using mycelial growth rate method
Good pathogen, aseptically with a diameter of 5mm card punch, bacteria cake is cut from colony edge, is connect bacteria cake with transfer needle
In on the culture medium flat plate of different agents concentration, putting 22 DEG C, cultivate in saturated humidity incubator；When control group bacterium colony covers with, survey
Colony diameter is measured, calculates the percentage that each chemicals treatment inhibits mycelial growth, passes through the probit value of inhibiting rate and series concentration
To the linear regression analysis between numerical value, the EC of each medicament is obtained50Value calculates the co-toxicity coefficient of mixture with the abundant methods of Sun Yun（CTC）,
Activity of the reagent agent to germ is evaluated with this.
The co-toxicity coefficient of complex preparation（CTC）>=120 show as synergistic effect；CTC≤80 show as antagonism；80 ＜
CTC ＜ 120 show as summation action.
1 fluopyram of table measures the mixture synergy of graw mold of tomato with fenhexamid
Synergy measurement result shows：Fluopyram presses 1 with fenhexamid:100~80:1 is mixed, to botrytis cinerea
Show different activity：When ratio is 1:80~60:When 1, synergistic effect is shown as；When ratio is 1:60~40:When 1, increase
Effect effect becomes apparent from；When ratio is 1:30~20:When 1, synergistic effect is the most notable.
The mixture synergy of peach brown rot is measured.
In order to prevent the peach brown rot in agricultural production, we are mutually multiple with the progress of fluopyram and fenhexamid
The synergy research matched somebody with somebody, specific method are as follows.
Experiment is using peach brown rot（Monilinia laxa）For test object.The investigational agent that active compound is configured to need
Single dose and each Mixed Pharmacy are set 5 various concentration gradients by agent（On the basis of pilot study result, bacteriostasis rate 5%~
It is set in the range of 90% by geometric progression）.If clear water compares, it is repeated 4 times.Experiment will be cultivated using mycelial growth rate method
Pathogen, aseptically with a diameter of 5mm card punch, bacteria cake is cut from colony edge, is connected to bacteria cake with transfer needle
On the culture medium flat plate of different agents concentration, 25 DEG C are put, cultivate in saturated humidity incubator；When control group bacterium colony covers with, measurement
Colony diameter calculates the percentage that each chemicals treatment inhibits mycelial growth, passes through the probit value of inhibiting rate and pair of series concentration
The EC of each medicament is obtained in linear regression analysis between numerical value50Value calculates the co-toxicity coefficient of mixture with the abundant methods of Sun Yun（CTC）, with
This evaluates activity of the reagent agent to germ.
The co-toxicity coefficient of complex preparation（CTC）>=120 show as synergistic effect；CTC≤80 show as antagonism；80 ＜
CTC ＜ 120 show as summation action.
2 fluopyram of table measures the mixture synergy of peach brown rot with fenhexamid
Synergy measurement result shows：Fluopyram presses 1 with fenhexamid:100~80:1 is mixed, to Monilinia fructicola table
Reveal different activity：When ratio is 1:80~60:When 1, synergistic effect is shown as；When ratio is 1:60~40:When 1, synergy
Effect becomes apparent from；When ratio is 1:30~20:When 1, synergistic effect is the most notable.
The mixture synergy of powdery mildew of cucumber is measured.
In order to prevent the powdery mildew of cucumber in agricultural production, we with the progress of fluopyram and fenhexamid mutually
The synergy research of compounding, specific method are as follows.
Subjects are cucumber powdery mildew's pathogen（Sphaerotheca fuliginea）.The experiment that active compound is configured to need
Medicament, test method reference《The 6th part of farm-chemical indoor determination test rule fungicide：The synergy of mixture measures》With
《The 11st part of farm-chemical indoor determination test rule fungicide：Prevent cucurbits powdery mildew experiment pot-culture method》.
Single dose and each Mixed Pharmacy are set into 5 various concentration gradients first（On the basis of pilot study, bacteriostasis rate exists
It is set in the range of 5%~90% by geometric progression）.If blank control is repeated 4 times.Using pot-culture method, liquid is uniformly sprayed on
Blade face, it is spare after liquid natural air drying.With spore suspension spray inoculation, then natural air drying moves to thermostatic chamber, in temperature
Under conditions of 20~24 DEG C, 7d~10d is cultivated.When blank control disease leaf rate reaches more than 80%, classification investigation is got a haircut everywhere
State of an illness condition often handles at least 30 leaves of investigation.Grade scale is：
0 grade：It is disease-free；
1 grade：Lesion area accounts for less than the 5% of entire leaf area；
3 grades：Lesion area accounts for the 5%~15% of entire leaf area；
5 grades：Lesion area accounts for the 15%~25% of entire leaf area；
7 grades：Lesion area accounts for the 25%~50% of entire leaf area；
9 grades：Lesion area accounts for the 50%~75% of entire leaf area；
11 grades：Lesion area accounts for more than the 75% of entire leaf area；
According to survey data, the disease index and control effect of each processing are calculated.Pass through pair of preventive effect niqueMin and series concentration
The EC50 values of each medicament are obtained in linear regression analysis between numerical value.
The co-toxicity coefficient of mixture is calculated with the abundant methods of Sun Yun（CTC）, activity of the reagent agent to germ is evaluated with this.Compounding
The co-toxicity coefficient of preparation（CTC）>=120 show as synergistic effect；CTC≤80 show as antagonism；80 ＜ CTC ＜ 120 are showed
For summation action.
3 fluopyram of table measures the mixture synergy of powdery mildew of cucumber with fenhexamid
Synergy measurement result shows：Fluopyram presses 1 with fenhexamid:100~80:1 is mixed, to cucumber powdery mildew's pathogen
Show different activity：When ratio is 1:80~60:When 1, synergistic effect is shown as；When ratio is 1:60~40:When 1, increase
Effect effect becomes apparent from；When ratio is 1:30~20:When 1, synergistic effect is the most notable.
The mixture synergy of early blight of tomato is measured.
In order to prevent the early blight of tomato in agricultural production, we with the progress of fluopyram and fenhexamid mutually
The synergy research of compounding, specific method are as follows.
Experiment is using tomato early blight bacterium（Alternaria solani）For test object.Active compound is configured to what is needed
Single dose and each Mixed Pharmacy are set 5 various concentration gradients by test medicine（On the basis of pilot study result, bacteriostasis rate
It is set in the range of 5%~90% by geometric progression）.If clear water compares, it is repeated 4 times.Experiment, will using mycelial growth rate method
Aseptically with a diameter of 5mm card punch, bacteria cake is cut from colony edge for cultured pathogen, with transfer needle by bacterium
Cake is connected on the culture medium flat plate of different agents concentration, is put 24 DEG C, is cultivated in saturated humidity incubator；Treat that control group bacterium colony covers with
When, colony diameter is measured, calculates the percentage that each chemicals treatment inhibits mycelial growth, it is dense by the probit value and series of inhibiting rate
Degree to the linear regression analysis between numerical value, the EC of each medicament is obtained50Value calculates the co-toxicity coefficient of mixture with the abundant methods of Sun Yun
（CTC）, activity of the reagent agent to germ is evaluated with this.
The co-toxicity coefficient of complex preparation（CTC）>=120 show as synergistic effect；CTC≤80 show as antagonism；80 ＜
CTC ＜ 120 show as summation action.
4 fluopyram of table measures the mixture synergy of early blight of tomato with fenhexamid
Synergy measurement result shows：Fluopyram presses 1 with fenhexamid:100~80:1 is mixed, to tomato early blight bacterium
Show different activity：When ratio is 1:80~60:When 1, synergistic effect is shown as；When ratio is 1:60~40:When 1, increase
Effect effect becomes apparent from；When ratio is 1:30~20:When 1, synergistic effect is the most notable.
The mixture synergy of pear scab is measured.
In order to prevent the pear scab in agricultural production, we with the progress of fluopyram and fenhexamid mutually
The synergy research of compounding, specific method are as follows.
Experiment is using pear cucumerinum（Venturia pirina）For test object.The experiment that active compound is configured to need
Single dose and each Mixed Pharmacy are set 5 various concentration gradients by medicament（On the basis of pilot study result, bacteriostasis rate is 5%
It is set in the range of~90% by geometric progression）.If clear water compares, it is repeated 4 times.Experiment will be cultivated using mycelial growth rate method
Good pathogen, aseptically with a diameter of 5mm card punch, bacteria cake is cut from colony edge, is connect bacteria cake with transfer needle
In on the culture medium flat plate of different agents concentration, putting 21 DEG C, cultivate in saturated humidity incubator；When control group bacterium colony covers with, survey
Colony diameter is measured, calculates the percentage that each chemicals treatment inhibits mycelial growth, passes through the probit value of inhibiting rate and series concentration
To the linear regression analysis between numerical value, the EC of each medicament is obtained50Value calculates the co-toxicity coefficient of mixture with the abundant methods of Sun Yun（CTC）,
Activity of the reagent agent to germ is evaluated with this.
The co-toxicity coefficient of complex preparation（CTC）>=120 show as synergistic effect；CTC≤80 show as antagonism；80 ＜
CTC ＜ 120 show as summation action.
5 fluopyram of table measures the mixture synergy of pear scab with fenhexamid
Synergy measurement result shows：Fluopyram presses 1 with fenhexamid:100~80:1 is mixed, to pear cucumerinum table
Reveal different activity：When ratio is 1:80~60:When 1, synergistic effect is shown as；When ratio is 1:60~40:When 1, synergy
Effect becomes apparent from；When ratio is 1:30~20:When 1, synergistic effect is the most notable.
In order to which the present invention is better described, present invention is described further with reference to embodiment, in formula
Percentage is weight percentage.
Example of formulations 1
Weigh 25% fluopyram, 10% fenhexamid, 5% aliphatic alcohol polyoxyvinethene phosphate, 6% alkylnaphthalene sulfonate formaldehyde
Condensation product, 4% sodium alkyl sulfonate, talcum powder are filled up to 100% parts by weight.Above-mentioned raw materials are through mixing, ultra micro air-flow crushing, mixing
Processing step is prepared into 35% fluopyram fenhexamid wettable powder.
Example of formulations 2
Weigh 20% fluopyram, 25% fenhexamid, 6% calcium lignosulfonate, 3% alkylnaphthalene sulfonate formaldehyde condensation products,
2.5% lauryl sodium sulfate, attapulgite are filled up to 100% parts by weight.Above-mentioned raw materials are through mixing, ultra micro air-flow crushing, mixed
It closes processing step and is prepared into 45% fluopyram fenhexamid wettable powder.
Example of formulations 3
Weigh 15% fluopyram, 10% fenhexamid, 5% polycarboxylate T36,3% Negel, 3% Nekal BX（Two
Sodium butylnaphthalenesulfonate）, 2% lauryl sodium sulfate, 2% polyethylene glycol, fine particle calcium carbonate adds to 100% parts by weight.The frequent regulation of above-mentioned raw materials
The method of water intaking dispersible granule i.e. mixing, ultra micro air-flow crushing, mixing, granulation step produces 25% fluopyram ring acyl bacterium
Aqueous amine dispersible granule.
Example of formulations 4
Weigh 10% fluopyram, 30% fenhexamid, 8% polycarboxylate TERSPERSE 2700,5% sodium lignin sulfonate, 1%
Nekal BX（Nekal）, 1% lauryl sodium sulfate, 2% starch, talcum powder adds to 100% parts by weight.Above-mentioned original
The method for expecting frequent regulation water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step produce 40% fluorine pyrrole bacterium acyl
Amine fenhexamid water dispersible granules.
Example of formulations 5
Weigh 5% fluopyram, 25% fenhexamid, 3% polycarboxylate, 4% phenethyl phenol polyoxyethylene groups ether phosphate, 5% alkane
Base sodium sulphate, 0.4% carboxymethyl cellulose, 3% sorbierite, 0.3% sodium benzoate, 1% butanol, deionized water add to 100% weight
Part.Above-mentioned raw materials disperse 30min, are sanded with sand mill to grain size D through mixing, high speed shear9030% fluorine pyrrole is made after less than 10 μm
Bacterium amide fenhexamid suspending agent.
Example of formulations 6
Weigh 15% fluopyram, 5% fenhexamid, 5% alkyl naphthalene formaldehyde condensation product sodium sulfonate, 5% phenethyl phenol polyoxyethylene
Base ether phosphate, 5% sodium alkyl sulfate, 0.4% carboxyethyl cellulose, 4% glycerine, 0.2% potassium sorbate, 2% octanol, deionization
Water adds to 100% parts by weight.Above-mentioned raw materials disperse 30min, are sanded with sand mill to grain size D through mixing, high speed shear90Less than 10 μ
20% fluopyram fenhexamid suspending agent is made after m.
Example of formulations 7
Weigh 14% fluopyram, 6% fenhexamid, 4% 3 phenethyl phenol polyoxyethylene ether phosphate, 3% dispersing agent NNO,
4% dispersant TERSPERSE4894,6% castor oil, 5% methyl oleate, 5% this disk -60#, 2% dispersant TERSPERSE 2500,
2% aluminium-magnesium silicate, 0.5% xanthans, 5% ethylene glycol, 1% epoxychloropropane, 0.3% benzoic acid, 0.4% organic silicon defoamer S-29,
Deionized water adds to 100% parts by weight.Above-mentioned raw materials are uniformly mixed, and high speed shear disperses 30min, are made after being sanded with sand mill
20% fluopyram fenhexamid suspension emulsion.
Example of formulations 8
Weigh 18% fluopyram, 4% fenhexamid, 6% dispersing agent NNO, 5% dispersant TERSPERSE2425,4% oleic acid first
Ester, 5% soybean oil, 6% agriculture breast 1601#, 4% Tween-60 #, 2% alkylphenol-polyethenoxy base ether phosphate, 2% polyvinyl alcohol, 0.2%
Xanthans, 5% ethylene glycol, 3% triphenyl phosphite, 0.2% sodium benzoate, 0.5% octanol, deionized water add to 100% parts by weight.
Above-mentioned raw materials are uniformly mixed, and high speed shear disperses 30min, and 22% fluopyram fenhexamid is made after being sanded with sand mill
Suspension emulsion.
Example of formulations 9
Weigh 6% fluopyram, 20% fenhexamid, 5% agriculture breast 1601,4% Nonyl pheno（EO=10）Ether phosphate,
5% Span60,2% this disk -60#, 1% epoxychloropropane, 2% glycerine, 5% dimethylbenzene, 0.3% aluminium-magnesium silicate,
0.5% sodium benzoate, deionized water add to 100% parts by weight.26% fluorine pyrrole bacterium is made through mixing, high speed shearing emulsification in above-mentioned raw materials
Amide fenhexamid aqueous emulsion.
Example of formulations 10
Weigh 16% fluopyram, 8% fenhexamid, 3% agriculture breast 2201#, 2% Nonyl pheno（EO=10）Ether phosphate,
4% Tween-60 #, 5% propylene glycol, 10% solvent naphtha S-180,5% toluene, 0.2% xanthans, 0.5% benzoic acid, deionized water add to
100% parts by weight.24% fluopyram fenhexamid aqueous emulsion is made through mixing, high speed shearing emulsification in above-mentioned raw materials.
Example of formulations 11
Weigh 4% fluopyram, 6% fenhexamid, 8% Nongru-700 #, 6% agriculture breast 500#, 4% agriculture breast 1601#, 15% cyclohexanone,
5% toluene, 3% isopropanol, through dissolving completely and being uniformly mixed, deionized water adds to 100% parts by weight, and 10% fluorine pyrrole is made after stirring
Bacterium amide fenhexamid microemulsion.
Example of formulations 12
Weigh 12% fluopyram, 3% fenhexamid, 5% agriculture breast 2201,6% polysorbate60-#, 25% solvent naphtha S-150,5% diformazan
Benzene, 5% isobutanol, through dissolving completely and being uniformly mixed, deionized water adds to 100% parts by weight, and 15% fluorine pyrrole bacterium acyl is made after stirring
Amine fenhexamid microemulsion.
Example of formulations 13
Weigh 12% fluopyram, 10% fenhexamid, 4% Arabic gum, 5% alkyl benzene calcium sulfonate, 6% linseed oil, 4% benzyl two
Sylvan polyoxyethyl ether, 3% sodium hydroxide and hydrochloric acid, 1% organic silicon defoamer, deionized water add to 100% parts by weight.It will be living
Property ingredient, macromolecule cyst material, solvent be mixed into homogeneous oil phase, oil phase is added in aqueous phase solution, it is solid after shearing is scattered
22% fluopyram fenhexamid microcapsule suspending agent is made after change.
Example of formulations 14
Weigh 10% fluopyram, 6% fenhexamid, 6% sodium alginate, 8% aliphatic alcohol polyethenoxy base ether, 5% aliphatic ester,
4% benzyl dimethyl phenol polyoxyethyl ether, 10% sodium hydroxide and sorbic acid, 1% hexanol, deionized water add to 100% parts by weight.It will
Active ingredient, macromolecule cyst material, solvent are mixed into homogeneous oil phase, and oil phase is added in aqueous phase solution, after shearing is scattered
16% fluopyram fenhexamid microcapsule suspending agent is made after curing.
Example of formulations 15
Weigh 5% fluopyram, 10% fenhexamid, 8% urea, 5% formaldehyde, 10% castor oil polyoxyethylene ether, 5% fatty acid polyglycol
Ethylene oxide ester, 2% lauryl sodium sulfate, 4% propylene glycol, 1% methylcellulose, 0.6% butanol, deionized water supply surplus.
Urea and formaldehyde are added in reaction kettle with frequency control, the pH value that solution is adjusted with sodium hydroxide solution is left to 7.5~8.5
The right side then heats to 55~70 DEG C, and stable urea resin prepolymer is obtained by the reaction.A certain amount of fenhexamid is taken to be dissolved in solvent
In, it is added to the water after addition emulsifier for mixing is uniform, under high shear homogeneous, is made into the type stable emulsions of O/W containing emulsifying dispersant.
Above-mentioned urea resin prepolymer is added in lotion, pH value is adjusted, polymerisation occurs under acid catalysed conditions, makes oil phase thing
Matter is wrapped, and forms microcapsule granule.Slowly heating cures, and temperature is controlled at 45~55 DEG C, 1~1.5h of hardening time,
Dispersant is added, microcapsule suspending agent containing fenhexamid is first made；Fluopyram and water and other auxiliary agents are cut in reaction kettle
After cutting uniformly, it is sanded in sand mill, suspending agent grain size D90 is made to can be made into the suspension of containing fluopyram below 5 μm
Agent.The suspending agent of containing fluopyram and the micro-capsule suspension containing fenhexamid are mixed evenly in proportion, you can system
Into 15% fluopyram fenhexamid microcapsule suspension-suspendinagent agent.
Example of formulations 16
Weigh 16% fluopyram, 6% fenhexamid, 6% urea, 5% formaldehyde, 10% sorbitan monostearate, 7% fatty amine
Polyoxyethylene ether, 5 neopelexes, 3% glycerine, 1.5% xanthans, 0.5% octanol, deionized water supply surplus.It presses
According to the processing method of example of formulations 15, you can 22% fluopyram fenhexamid microcapsule suspension-suspendinagent agent is made.
Example of formulations 17
Weigh 14% fluopyram, 8% fenhexamid, 5% Negel, 5%BY-140,8% Tween-60 #, 8% agriculture breast
2201#, 4% alkylphenol polyoxyethylene ether phosphate, 3% aluminium-magnesium silicate, 5% bentonite, small wheat oil add to 100% parts by weight.It is above-mentioned
Raw material disperses 30min through mixing, high speed shear, and it is dispersible that 22% fluopyram fenhexamid is made after being sanded with sand mill
Oil-suspending agent.
Example of formulations 18
Weigh 22% fluopyram, 12% fenhexamid, 5% sodium polycarboxylate, 8% Tween-60 #, 7%BY-125,5% sodium naphthalene sulfonate,
1% bentonite, 4% ethylene glycol, soybean oil add to 100% parts by weight.Above-mentioned raw materials disperse 30min, use sand through mixing, high speed shear
Grinding machine makes the 34% dispersible oil-suspending agent of fluopyram fenhexamid after being sanded.
Example of formulations 19
Weigh 25% fluopyram, 20% fenhexamid, 8% neopelex, 5% fatty alcohol polyoxyethylene ether, 4% poly-
Vinyl alcohol, 2% polyethylene glycol, 5% butanol, precipitated calcium carbonate add to 100% parts by weight.Above-mentioned slurry carries out wet method powder with sand mill
It is broken that suspension slurry is made, spray drying granulation is then carried out, 45% fluopyram is made by sieving in the particle after granulation
Fenhexamid dry suspending agent.
Example of formulations 20
Weigh 15% fluopyram, 25% fenhexamid, 5% dioctyl sodium sulphosuccinate, 8% neopelex, 5%
Sodium sulphate, 5% carboxymethyl cellulose, 2% hexanol, white carbon add to 100% parts by weight.Above-mentioned slurry carries out wet method powder with sand mill
It is broken that suspension slurry is made, spray drying granulation is then carried out, 40% fluopyram is made by sieving in the particle after granulation
Fenhexamid dry suspending agent.
Biological Examples 1：Prevent graw mold of tomato field control effectiveness test.
Example of formulations 1 has been carried out in Shaanxi Province Jingyang County within 2017（35% fluopyram fenhexamid wettable powder
Agent), example of formulations 3（25% fluopyram fenhexamid water dispersible granules）, example of formulations 5（30% fluorine pyrrole bacterium acyl
Amine fenhexamid suspending agent), example of formulations 7（20% fluopyram fenhexamid suspension emulsion), example of formulations 9
（26% fluopyram fenhexamid aqueous emulsion) prevention graw mold of tomato field trial, the medicament is demonstrated to tomato gray mould
The control effect and the security to tomato of disease.
Trial crops are tomato, and controlling object is graw mold of tomato（Botrytis cinerea）.Experiment is located at Jingyang County
Yunyang town, experimental plot physical features is flat, and soil is loam, and middle fertility, pH value 6.9, fertilizer and water management is medium during experiment.Investigational agent
Agent and dosage refer to table 6.Blank control separately is set, often handles 4 repetitions, per 30 ㎡ of cell, totally 32 cells, random district's groups are arranged
Row.Using conventional spray-on process, mu dispenser liquid 45kg is uniformly sprayed at leave dual sides.
Investigation and statistical method：State of an illness radix is investigated before the 1st dispenser, 10~14d is reinvestigated after last time dispenser
Once, investigate 2 times altogether, dispenser 2 times.Per cell using five point sampling, every is investigated 3 plants, and whole blades of every plant of investigation are counted
Calculate disease index.Graw mold of tomato grade scale（In units of blade）：
0 grade：Disease-free spot；
1 grade：Single blade has scab 3；
3 grades：Single blade has scab 4~6；
5 grades：Single blade has scab 7~10；
7 grades：Single blade has scab 11~20, and part is intensive in flakes；
9 grades：Single blade has scab is intensive to account for more than leaf area a quarter.
Disease index=[∑ (the disease numbers of sheets at different levels × opposite value of series)/(investigation total leaf number × 9)] × 100
Control effect (%)=[1- (disease index after disease index × processing dispenser before control dispenser)/（The state of an illness refers to after control dispenser
Disease index before number × processing dispenser] × 100
Table 6 prevents graw mold of tomato field test results
Table of field test results is bright, and more than example of formulations has graw mold of tomato good control effect, respectively by 75g
a.i./hm2It sprays 2 times, the preventive effect of 10 days is above 94% after the 2nd medicine, hence it is evident that better than 41.7% fluopyram of comparison medicament
Suspending agent 75g a.i./hm2, 50% fenhexamid suspending agent 180g a.i./hm2Preventive effect.By anti-to 10 days after the 2nd medicine
Significance difference analysis is imitated, difference reaches the pole level of signifiance.
Security survey to tomato is observed after spray for several days after the 1st day and medicine, and each test process is to tomato without poisoning
Phenomenon occurs.
Biological Examples 2：Prevent powdery mildew of cucumber field trial.
Example of formulations 11 has been carried out in Shouguang City of Shandong Province within 2017（10% fluopyram fenhexamid micro emulsion
Agent）, example of formulations 13（22% fluopyram fenhexamid microcapsule suspending agent）, example of formulations 15（15% fluorine pyrrole bacterium acyl
Amine fenhexamid microcapsule suspension-suspendinagent agent）, example of formulations 17（The dispersible oil of 22% fluopyram fenhexamid suspends
Agent), example of formulations 19（45% fluopyram fenhexamid dry suspending agent) prevention powdery mildew of cucumber field trial, verification
Control effect of the medicament to powdery mildew of cucumber and the security to cucumber.Trial crops are cucumber, and controlling object is cucumber
Powdery mildew（Sphaerotheca fuliginea）.Experiment is located at Shouguang City rice field Zhen Dong rice fields village, and experimental plot physical features is flat, soil
Earth is loam, and middle fertility, pH value 6.9, fertilizer and water management is medium during experiment.Test medicine and dosage refer to table 7.Separately set blank
Control often handles 4 repetitions, and per 30 ㎡ of cell, totally 32 cells, random district's groups arrange.Using conventional spray-on process, mu dispenser liquid
45kg is uniformly sprayed at leave dual sides.
Investigation and statistical method：State of an illness radix is investigated before dispenser, 10~14d is reinvestigated once after last time dispenser, altogether
Investigation 2 times.Take at random per cell at 4 points, whole blades of every 2 plants of investigation, every leaf accounts for the percentage of leaf area according to scab
Classification record.Stage division：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for less than the 5% of entire leaf area；
3 grades：Lesion area accounts for the 6%~10% of entire leaf area；
5 grades：Lesion area accounts for the 11%~20% of entire leaf area；
7 grades：Lesion area accounts for the 21%~40% of entire leaf area；
9 grades：Lesion area accounts for more than the 40% of entire leaf area.
Disease index=[∑ (the disease numbers of sheets at different levels × opposite value of series)/(investigation total leaf number × 9)] × 100
Control effect (%)=[1- (disease index after disease index × processing dispenser before control dispenser)/（The state of an illness refers to after control dispenser
Disease index before number × processing dispenser] × 100
Table 7 prevents powdery mildew of cucumber field test results
Table of field test results is bright, more than 5 example of formulations have good control effect to powdery mildew of cucumber, respectively by effective
15g/ mus of ingredient is sprayed 2 times, is above 92.25% to the preventive effect of 10 days after the 2nd medicine of powdery mildew of cucumber, hence it is evident that better than comparison medicine
41.7% fluopyram suspending agent 75g a.i./hm of agent2, 50% fenhexamid suspending agent 180g a.i./hm2Preventive effect.Pass through
To 10 days preventive effect significance difference analysis after the 2nd medicine, difference reaches the pole level of signifiance.
Security survey to cucumber is observed after spray for several days after the 1st day and medicine, and each test process is to cucumber without poisoning
Phenomenon occurs.
Except graw mold of tomato and powdery mildew of cucumber, above-mentioned example of formulations active ingredient dosage for 75g a.i./
hm2When, also there is synergistic effect to peach brown rot, early blight of tomato and pear scab, preventive effect is up to more than 90%.
Above example illustrates that the first active ingredient fluopyram is with the second active ingredient fenhexamid by weight 1：
80~60：1 compounding, can be made into wettable powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspension
Agent, microcapsule suspension-suspendinagent agent, dispersible oil-suspending agent, dry suspending agent dosage form, to crop gray mold, brown rot, powdery mildew, morning
Epidemic disease, scab have significant control effect, and synergistic effect is apparent, and dosage is few, control effect is high and good to vegetable safety
It is good.
In conclusion the composition of the present invention is using two kinds of active components compound scheme, activity and bactericidal effect are not
It is the simple superposition of each component activity, compared with existing unitary agent, in addition to there is significant bactericidal effect, more has significantly
Synergistic effect, it is good to crop safety, meet the security requirement of pesticidal preparations.
Claims (7)
1. a kind of bactericidal composition containing fluopyram and fenhexamid, which is characterized in that by the first active ingredient fluorine pyrrole
The weight ratio of bacterium amide, the second active ingredient fenhexamid and auxiliary agent composition, fluopyram and fenhexamid is 1：80~60：
1。
2. the bactericidal composition containing fluopyram and fenhexamid according to claim 1, which is characterized in that fluorine pyrrole bacterium
The weight ratio of amide and fenhexamid is 1：60~40：1.
3. the bactericidal composition according to claim 1 or claim 2 containing fluopyram and fenhexamid, which is characterized in that fluorine
The weight ratio of pyrrole bacterium amide and fenhexamid is 1：30~20：1.
4. the bactericidal composition containing fluopyram and fenhexamid according to claim 1, which is characterized in that fluorine pyrrole bacterium
The sum of content of amide and fenhexamid is the 1%~80% of the composition total weight.
5. the bactericidal composition containing fluopyram and fenhexamid according to claim 4, which is characterized in that fluorine pyrrole bacterium
The sum of content of amide and fenhexamid is the 1%~50% of the composition total weight.
6. the bactericidal composition containing fluopyram and fenhexamid according to claim 1, it is characterised in that described group
Agent type is closed to hang for wettable powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, micro-capsule
Floating-suspending agent, dispersible oil-suspending agent, dry suspending agent.
7. bactericidal composition according to claim 1 containing fluopyram and fenhexamid prevention crop gray mold,
Brown rot, powdery mildew, early blight, the purposes on scab.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711341669.7A CN108077270A (en) | 2017-12-14 | 2017-12-14 | A kind of bactericidal composition containing fluopyram and fenhexamid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711341669.7A CN108077270A (en) | 2017-12-14 | 2017-12-14 | A kind of bactericidal composition containing fluopyram and fenhexamid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108077270A true CN108077270A (en) | 2018-05-29 |
Family
ID=62176478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711341669.7A Pending CN108077270A (en) | 2017-12-14 | 2017-12-14 | A kind of bactericidal composition containing fluopyram and fenhexamid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108077270A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108633887A (en) * | 2018-08-17 | 2018-10-12 | 陕西上格之路生物科学有限公司 | A kind of bactericidal composition containing fluxapyroxad and fenhexamid |
| CN114557342A (en) * | 2022-02-24 | 2022-05-31 | 西安近代化学研究所 | Preparation method of fluopyram microcapsule suspending agent |
| EP4011209A1 (en) * | 2020-12-14 | 2022-06-15 | Bayer Aktiengesellschaft | Storage stable aqueous suspension concentrates |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1917760A (en) * | 2004-02-12 | 2007-02-21 | 拜尔农科股份有限公司 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis |
-
2017
- 2017-12-14 CN CN201711341669.7A patent/CN108077270A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1917760A (en) * | 2004-02-12 | 2007-02-21 | 拜尔农科股份有限公司 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108633887A (en) * | 2018-08-17 | 2018-10-12 | 陕西上格之路生物科学有限公司 | A kind of bactericidal composition containing fluxapyroxad and fenhexamid |
| EP4011209A1 (en) * | 2020-12-14 | 2022-06-15 | Bayer Aktiengesellschaft | Storage stable aqueous suspension concentrates |
| WO2022128955A1 (en) * | 2020-12-14 | 2022-06-23 | Bayer Aktiengesellschaft | Storage stable aqueous suspension concentrates |
| CN114557342A (en) * | 2022-02-24 | 2022-05-31 | 西安近代化学研究所 | Preparation method of fluopyram microcapsule suspending agent |
| CN114557342B (en) * | 2022-02-24 | 2024-03-29 | 西安近代化学研究所 | Preparation method of fluopyram microcapsule suspending agent |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103749522B (en) | The bactericidal composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate-containing and acid amide fungicides | |
| CN105454245A (en) | Sterilization composition containing metrafenone and fluxapyroxad | |
| CN108077270A (en) | A kind of bactericidal composition containing fluopyram and fenhexamid | |
| CN104920389A (en) | Weeding composite comprising oxaziclomefone | |
| CN106937635A (en) | A kind of bactericidal composition of fluorine-containing azoles bacterium acyl azanol and jinggangmeisu | |
| CN107232216A (en) | A kind of bactericidal composition containing tetrazolium pyrrole urethane and acid amide fungicides | |
| CN105638698A (en) | Sterilization composition with fluopicolide and valifenalate | |
| CN106561698A (en) | Sterilization composition containing fenhexamid | |
| CN102239850B (en) | Fluopicolpkd-containing agricultural bactericidal composition | |
| CN103749479B (en) | The bactericidal composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate-containing and acid amide fungicides | |
| CN103283770B (en) | Insecticidal composition containing cycolxylidin and metaflumizone | |
| CN108064848A (en) | A kind of bactericidal composition containing fluopyram and amine benzene pyrrole bacterium ketone | |
| CN104798790A (en) | Sterilizing composition containing SYP-Z048 and picoxystrobin | |
| CN108770856A (en) | A kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and amine benzene pyrrole bacterium ketone | |
| CN107279162A (en) | A kind of bactericidal composition of the urethane of pyrrole containing tetrazolium | |
| CN105076212B (en) | A kind of bactericidal composition containing bacillus subtilis and 2-cyano-3-amino-3-phenylancryic acetate | |
| CN106879614A (en) | A kind of bactericidal composition and application thereof | |
| CN105494417A (en) | Sterilization composition containing metalaxyl-M and phosethyl-al | |
| CN108633887A (en) | A kind of bactericidal composition containing fluxapyroxad and fenhexamid | |
| CN107125245B (en) | A kind of bactericidal composition containing nonylphenolsulfonate copper and fluopicolide | |
| CN107347900A (en) | A kind of bactericidal composition of the urethane of pyrrole containing tetrazolium | |
| CN109169673A (en) | A kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and cyflufenamid | |
| CN108902157A (en) | A kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and fenhexamid | |
| CN105165828B (en) | Bactericidal composition containing metrafenone and meptyldinocap | |
| CN106689181A (en) | Bactericidal composition containing fenpyrazamine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180529 |
|
| RJ01 | Rejection of invention patent application after publication |