CN106535890A - 5‑取代的吲唑‑3‑羧酰胺及其制备和应用 - Google Patents

5‑取代的吲唑‑3‑羧酰胺及其制备和应用 Download PDF

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Publication number
CN106535890A
CN106535890A CN201580026082.XA CN201580026082A CN106535890A CN 106535890 A CN106535890 A CN 106535890A CN 201580026082 A CN201580026082 A CN 201580026082A CN 106535890 A CN106535890 A CN 106535890A
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pyridin
carboxylic acid
acid amides
bases
methyl
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Chinese (zh)
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J·胡德
S·K·克西
D·M·华莱士
G·K·米塔帕里
B·J·霍菲勒纳
C·C·马克
V·博露
B·伊斯特曼
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WINTHERIX LLC
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WINTHERIX LLC
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CN201580026082.XA 2014-03-20 2015-03-20 5‑取代的吲唑‑3‑羧酰胺及其制备和应用 Pending CN106535890A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461968350P 2014-03-20 2014-03-20
US61/968,350 2014-03-20
PCT/US2015/021847 WO2015143380A1 (en) 2014-03-20 2015-03-20 5-substituted indazole-3-carboxamides and preparation and use thereof

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CN106535890A true CN106535890A (zh) 2017-03-22

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Country Link
US (2) US9745271B2 (https=)
EP (1) EP3119393A4 (https=)
JP (1) JP6586104B2 (https=)
KR (1) KR20160135283A (https=)
CN (1) CN106535890A (https=)
BR (1) BR112016021626A2 (https=)
CA (1) CA2942687A1 (https=)
CL (1) CL2016002364A1 (https=)
IL (1) IL247713A0 (https=)
MA (1) MA39763A (https=)
MX (1) MX2016012208A (https=)
PE (1) PE20170127A1 (https=)
PH (1) PH12016501835A1 (https=)
RU (1) RU2016141088A (https=)
SG (2) SG11201607816UA (https=)
WO (1) WO2015143380A1 (https=)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112020501A (zh) * 2018-02-23 2020-12-01 萨穆梅德有限公司 5-杂芳基取代的吲唑-3-基甲酰胺类及其制备和用途
CN112135821A (zh) * 2018-05-07 2020-12-25 方济各安吉利克化学联合股份有限公司 作为糖原合酶激酶3β抑制剂的1H-吲唑-3-甲酰胺化合物
CN113735798A (zh) * 2021-09-27 2021-12-03 安徽美致诚药业有限公司 一种盐酸罗沙替丁醋酸酯的制备方法
WO2022052861A1 (zh) * 2020-09-09 2022-03-17 成都奥睿药业有限公司 5-取代吲哚3-酰胺衍生物及其制备方法和用途
CN114867718A (zh) * 2019-12-16 2022-08-05 韩国化学研究院 新型吲唑衍生物及其用途
CN115353512A (zh) * 2021-07-30 2022-11-18 上海翊石医药科技有限公司 一种杂环脲类化合物及其制备方法和用途
WO2023098699A1 (en) * 2021-12-01 2023-06-08 Nanjing Immunophage Biotech Co., Ltd Compounds and their uses as cd38 inhibitors

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EP3473099A1 (en) 2011-09-14 2019-04-24 Samumed, LLC Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors
PH12017500997A1 (en) 2012-04-04 2018-02-19 Samumed Llc Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
WO2014110086A2 (en) 2013-01-08 2014-07-17 Samumed, Llc 3-(benzoimidazol-2-yl)-indazole inhibitors of the wnt signaling pathway and therapeutic uses thereof
MX2016012208A (es) 2014-03-20 2017-01-26 Samumed Llc Indazol-3-carboxamidas 5-substituidas y preparacion y uso de las mismas.
WO2016040181A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040180A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040185A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof
WO2016040193A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
WO2016040190A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
WO2016040184A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
US10188634B2 (en) 2015-08-03 2019-01-29 Samumed, Llc 3-(3H-imidazo[4,5-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
US10206908B2 (en) 2015-08-03 2019-02-19 Samumed, Llc 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
US10226448B2 (en) 2015-08-03 2019-03-12 Samumed, Llc 3-(1H-pyrrolo[3,2-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridines and therapeutic uses thereof
US10206909B2 (en) 2015-08-03 2019-02-19 Samumed, Llc 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
US10350199B2 (en) 2015-08-03 2019-07-16 Samumed, Llc 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof
US10166218B2 (en) 2015-08-03 2019-01-01 Samumed, Llc 3-(1H-indol-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
US10519169B2 (en) 2015-08-03 2019-12-31 Samumed, Llc 3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
US10285982B2 (en) 2015-08-03 2019-05-14 Samumed, Llc 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
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