CN106520486A - Health wine for improving cough and abundant sputum - Google Patents

Health wine for improving cough and abundant sputum Download PDF

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Publication number
CN106520486A
CN106520486A CN201710020647.4A CN201710020647A CN106520486A CN 106520486 A CN106520486 A CN 106520486A CN 201710020647 A CN201710020647 A CN 201710020647A CN 106520486 A CN106520486 A CN 106520486A
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Prior art keywords
health promoting
promoting wine
cough
health
wine
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宋诗丽
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Zhuhai Focus Biological Research Institute Co Ltd
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Zhuhai Focus Biological Research Institute Co Ltd
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
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  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Insects & Arthropods (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Husbandry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to the field of health products and particularly relates to health wine for improving cough and abundant sputum. The health wine is prepared by the steps of grinding and decocting traditional Chinese medicines with effects of relieving cough and reducing sputum, such as saponaria, radix asteris, folium perillae, radix peucedani and liquorice, adding acacia honey, and carrying out sealed soaking in 52-degree white wine for one month. The health wine has the beneficial effects that the dissolution rate of effective components is relatively high, and the health effect is relatively good; the obtained health wine has good taste and is capable of enhancing the defense capability of the body, accelerating the curing process, relieving the cough and reducing the sputum; and by virtue of the synergistic interaction with the acacia honey, the health wine is capable of protecting the spleen, nourishing the stomach, clearing away heat and toxic materials, maintaining beauty and keeping young.

Description

A kind of health promoting wine for improving cough ant phlegm
Technical field
The invention belongs to field of health care products, and in particular to a kind of health promoting wine for improving cough ant phlegm.
Background technology
Cough, recurrent cough are a kind of commonly encountered diseases and frequently-occurring disease, are the cardinal symptom of respiratory system disease.Work as human infection Virus, antibacterial, microorganism, or various chemical factors, environmental factorss etc., or due to virus, antibacterial and various Factor causes the pathological changes that respiratory mucosa occurs, it is impossible to improve with the extinction of virus, antibacterial and various microorganisms.Cough is most Flu is common in, and the arch-criminal for catching a cold is virus mostly.Antibiotics are primarily directed to bacterium infection, to viral nothing Effect.Not only abuse of antibiotics does not improve symptom during cough, antibacterial can be promoted on the contrary to produce drug resistance, infection occurs when real When, medicine is possible to lose curative effect.Although central antitussive such as codeine antitussive effect is preferably, life-time service easily into Addiction, produces dependence to medicine, and the psychology such as dysphoria, nausea and vomiting and physiological signs, therefore its application occurs after drug withdrawal It is strictly controlled.Expectorant is secreted by trachea and bronchus, when having a delicate constitution, deficiency of QI in middle-JIAO, and the expectorant of secretion will be excessive, excessive Expectorant can be detrimental to health, and when the damage of respiratory mucosa itself function, define the cough not recovered for a long time in treatment cough, Great pain is brought to patient, being also possible to of having develops into pulmonary heart disease and bring life danger, in order to improve respiratory mucosa The function of itself, on the basis for the treatment of protopathy, selects appropriate eliminating phlegm and stopping cough product, most important.
Chinese patent discloses cough relieving medicated wine (CN01134637), and the raw material components of the medicated wine are 5~10 parts of Fructus Citri Sarcodactylis, Rhizoma Cynanchi Stauntonii 3~15 parts, 5~15 parts of Bulbus Lilii, 5~15 parts of Folium Eriobotryae, 30~100 parts of Chinese liquor, 3~6 parts of white sugar.Above-mentioned Chinese medicine is sieved Select, crush, being put in Chinese liquor and add white sugar to soak 27 days, medicinal residues are removed in worry.The raw material of the cough relieving medicated wine has larger thorn Sharp nature and flavor road, has a certain impact to the mouthfeel of medicated wine.White sugar and Chinese liquor belong to apolar substance, have short of money in absorption of human body It is anti-, so adding white sugar affect the effect of medicated wine so that medicated wine could not give full play to its drug effect.
Patent No. CN 201410316704.x discloses a kind of nourishing the lung to arrest cough health promoting wine, is made up of following raw material: Radix Ophiopogonis 12-15 parts, Radix Rehmanniae 2-4 parts, Herba Dendrobii 4-8 parts, Semen Oroxyli 10-14 parts, Semen Sterculiae Lychnophorae 14-22 parts, Fructus Schisandrae Chinensis 6-10 parts, Mel 20-25 parts, ethanol 100-200 parts.Medical material is immersed in ethanol and is soaked 10-15 days, then filtered medicinal residues, then diluted with pure water Can be prepared by 30-50 °.The invention material is complicated, and immersion process will be carried out under the conditions of lucifuge, by simple immersion work Sequence, it is insufficient to the extracts active ingredients in material so that cough suppressing effect is bad.
The health product of the existing Chinese medicine composition for cough-relieving excessive phlegm, poor taste to body defenses ability and were fully recovered Cheng Zuoyong is poor, and health product are made up of a variety of Chinese crude drugs more, and directly immersion is obtained, and causes effective ingredient or the activity of medical material The extraction of component not exclusively, have impact on effect of final products.
The content of the invention
In order to solve prior art problem, the invention provides a kind of health promoting wine for improving cough ant phlegm.Formula is according to me The medicines and health protections such as state's Chinese medicine are theoretical for instructing, by herbal medicine immersions such as Saponaria officinalis, Radix Asteriss, Folium Perillae, Radix Peucedani, Radix Glycyrrhizaes in Chinese liquor So as to obtain a kind of health promoting wine that can improve cough ant phlegm, by increasing reticuloendothelial system activity, so as to enhancing body is anti- Imperial ability and recovery process, promote the mucus quantity coughed and make to produce in respiratory tract to increase, improve cough ant phlegm so as to reach Purpose.
A kind of health promoting wine for improving cough ant phlegm, is made up of the raw material of following weight portion:
Further, a kind of health promoting wine of described improvement cough ant phlegm, is made up of the raw material of following weight portion:
Further, a kind of health promoting wine of described improvement cough ant phlegm, is made up of the raw material of following weight portion:
Most preferably, a kind of health promoting wine of described improvement cough ant phlegm, is made up of the raw material of following weight portion:
Preferably, the health promoting wine of described a kind of improvement cough ant phlegm, the Chinese liquor are 52 degree.
Preferably, the health promoting wine of described a kind of improvement cough ant phlegm, the Mel is the acacia honey of fresh refining.
The health care method for preparing medicated wine of the present invention, comprises the following steps:
1) Saponaria officinalis, Radix Asteriss, Folium Perillae, Radix Peucedani, Radix Glycyrrhizae are cleaned and dries, crushed with pulverizer;
2) medical material after above-mentioned crushing is added and is boiled in the container equipped with Chinese liquor, Chinese liquor is 1 with the weight part ratio of medical material: 4;
3) boil medical filtration, cooling after 2h, after sterilizing clear liquid;
4) above-mentioned clear liquid is mixed with Mel in addition Chinese liquor, sealing obtains final product the health promoting wine after placing 1 month.
Heretofore described crude drug component and effect or feature are as described below:
Contain saporin and soap essence alcohol in Saponaria officinalis, reticuloendothelial system activity can be increased, so as to enhancing body is anti- Imperial ability and recovery process.Tablet, decoct can be made to take orally to improve cough, and the mucus quantity for making to produce in respiratory tract increases Plus, there is certain expectorant that goes to act on, can be used to treat bronchitis, cough and asthma.Additionally, Saponaria officinalis also have antidiarrheal and diuresis Effect.Saponaria officinalis extract has inhibiting bacteria and diminishing inflammation effect, therefore, Saponaria officinalis can also be used as the preservative of health promoting wine of the present invention.
Contain perillaldehyde in Folium Perillae, sweet taste is 2000 times of Saccharum Sinensis Roxb., is good sweeting agent, and be adapted to diabetes patient's food With.Perillaldehyde can adjust the overall sour-sweet degree of health promoting wine of the present invention, make health promoting wine flavor taste more preferably.
Radix Asteriss have warming the lung, the therapeutic method to keep the adverse QI flowing downwards, the function that expectorant, cough-relieving are coughed.Radix Asteriss are in vitro to escherichia coli, dysentery bacterium, change 7 kinds of Gram-negative enteral pathogenic bacterium such as shape bacterium, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus and vibrio cholera have certain Inhibitory action;And play the role of to resist pathogenic funguses.The cyclic peptide isolated is had been reported that from the n-Butanol fractoion of tatarian aster root Class compound has anti-tumor activity to S180.
The bitter in the mouth of Radix Peucedani, pungent, cold nature, function dissipate wind heat clearing away, lowering the adverse-rising QI to resolve phlegm.For cough due to pathogenic wind-heat's abundant expectoration, expectorant dyspnea of heat type is full, Cough up phlegm yellow thick etc..It is relatively effective a herb.
Radix Glycyrrhizae contains the important biological active substanceies of glycyrrhizin and flavonoid, has the function of antiinflammatory and resistance state reflection, Cough can be alleviated, pharyngalgia laryngitis is treated in eliminating the phlegm.
Acacia honey is top grade in honey, can protect spleen nourishing the stomach, heat-clearing and toxic substances removing, skin care healthy energy and blood capillary can be kept normally to resist Ability, vasodilator, reduce blood pressure, improve blood circulation, prevent sclerosis of blood vessels, can be used for prevention of stroke.Which contains acaciin And volatile oil, can cough-relieving, antibacterial, anti-corrosion;Taking acacia honey can reduce the irritability of nervus centraliss, play harmless somnifacient.It is long Phase, edible acacia honey can improve the emotion of people, reach mind tranquilizing and the heart calming effect.The overall acid of health promoting wine can be also adjusted in the present invention Sugariness, makes health promoting wine flavor taste more preferably.
Compared with prior art, the invention has the beneficial effects as follows:
(1) again cleaner liquid will be added in Chinese liquor after Traditional medicine infusion 2h so that effective ingredient dissolution rate is higher, health care effect Fruit is more preferably;(2) Saponaria officinalis, Radix Asteriss, Folium Perillae, Radix Peucedani, Radix Glycyrrhizae all effective ingredient containing relieving cough and removing sputum, several Chinese medicines are according to one The health promoting wine that fixed ratio is obtained, increases body defenses ability and recovery process, can alleviate cough, and eliminating the phlegm is cooperateed with acacia honey Potentiation, can protect spleen nourishing the stomach, heat-clearing and toxic substances removing, reach looks improving and the skin nourishing effect.(3) raw material of the invention is all belonging to food and medicine The medicine-food two-purpose that Surveillance Authority specifies can be used for the material of health food, have no toxic side effect, can long-term drink;(4) present invention Health promoting wine Saponaria officinalis and Radix Asteriss contain antibacterial substance, can play fungistatic effect, need not add preservative;(5) health promoting wine of the present invention In Folium Perillae in the perillaldehyde that contains be good sweeting agent, with acacia honey collective effect, other components in wine body can be adjusted Original acerbity, gives health promoting wine good mouthfeel;(6) health promoting wine of the present invention also has sleeping effect.
Specific embodiment
A kind of 1~4 formula of health promoting wine embodiment for improving cough ant phlegm is shown in Table one
Table one
Above-mentioned health care method for preparing medicated wine, step are as follows:
The health care method for preparing medicated wine of the present invention, comprises the following steps:
1) Saponaria officinalis, Radix Asteriss, Folium Perillae, Radix Peucedani, Radix Glycyrrhizae are cleaned and dries, crushed with pulverizer;
2) medical material after above-mentioned crushing is added and is boiled in the container equipped with Chinese liquor, Chinese liquor is 1 with the weight part ratio of medical material: 4;
3) boil medical filtration, cooling after 2h, after sterilizing clear liquid;
4) above-mentioned clear liquid is mixed with the acacia honey of fresh refining in addition Chinese liquor, sealing obtains final product described after placing 1 month Health promoting wine.
Comparative example 1
Difference with embodiment 1 is not add Saponaria officinalis, and other preparation conditions and method are same as Example 1.
Comparative example 2
Difference with embodiment 1 is not add Folium Perillae, and other preparation conditions and method are same as Example 1.
Comparative example 3
Difference with embodiment 1 is not add Radix Peucedani, and other preparation conditions and method are same as Example 1.
Comparative example 4
Difference with embodiment 1 is not add Radix Glycyrrhizae, and other preparation conditions and method are same as Example 1.
Cough-relieving efficacy validation
Experimentation
The patient for choosing 450 different age groups with cough, bronchitis or symptoms of asthma carries out observation experiment:
450 patients are divided into into 9 groups, one group of 50 people, every group of age composition are identical, correspond to embodiment 1~4 and contrast respectively Example 1~5, comparative example 5 take corresponding health promoting wine once daily for certain commercially available health promoting wine for improving cough ant phlegm, each 50ml, Drink before sleeping, be within one month a course for the treatment of.
Other health product are cut out during experiment.
450 patient age distributions and symptom are shown in Table two
Table two
Experimental result
Being improved with symptom and the obvious mitigation of few expectorant condition of illness being coughed less as effective standard, symptom is not improved as null criterion, knot Fruit is shown in Table three
Table three
Effectively It is invalid Effective percentage
Embodiment 1 50 0 100%
Embodiment 2 48 2 96%
Embodiment 3 49 1 98%
Embodiment 4 47 3 94%
Comparative example 1 25 25 50%
Comparative example 2 23 27 46%
Comparative example 3 24 26 48%
Comparative example 4 24 26 48%
Comparative example 5 32 18 64%
Health promoting wine of the present invention is drawn to chronic cough, tracheitiies, asthma by table three, it is flat that insomnia so symptom disorder significantly mitigates Effective percentage is 97%, and far above comparative example 1~5, embodiment 1 is even more and has reached 100%, it can be seen that health promoting wine pair of the present invention There is the effect of obvious eliminating phlegm and stopping cough and sleeping, the formula of embodiment 1 is optimum formula.The effective percentage of comparative example 1~4 is not More than 50%, comparative example visible Saponaria officinalis, Folium Perillae, Radix Peucedani, Radix Glycyrrhizae in health promoting wine of the present invention serve Synergistic Effect.
Embodiment 1~4 and 1~5 health promoting wine onset time of comparative example are shown in Table four, and comparative example 5 coughs many for certain commercially available improvement The health promoting wine of expectorant.
Table four
Can be seen that by table four the improvement time of patient of had clear improvement disease, between 30 days to 90 days, draws this The onset time of invention health promoting wine is 30 days to 90 days.And comparative example 1~5 has the trouble for being just obviously improved disease more than 90 days Person, it is seen that health promoting wine of the present invention has remarkable result on responding time, can improve disease faster.
Above example only illustrates embodiment of the present invention, the restriction not having to the present invention in any formula;It is any Professional and technical personnel is engaged in, and is all had the ability some changes to be made using the technology contents for disclosing or is modified, becomes equivalent and become The Equivalent embodiments of change, according to the technology of the present invention essence, carry out simply modification, equivalent variations and modification, belong to the present invention In the range of technical solution of the present invention.

Claims (8)

1. a kind of health promoting wine for improving cough ant phlegm, it is characterised in that the health promoting wine is made up of the raw material of following weight portion:
2. a kind of health promoting wine for improving cough ant phlegm according to claim 1, it is characterised in that the health promoting wine is by following The raw material composition of weight portion:
3. a kind of health promoting wine for improving cough ant phlegm according to claim 2, it is characterised in that the health promoting wine is by following The raw material composition of weight portion:
4. a kind of health promoting wine of the improvement cough ant phlegm according to any one of claim 3, it is characterised in that the health promoting wine It is made up of the raw material of following weight portion:
5. a kind of health promoting wine of the improvement cough ant phlegm according to any one of claim 1-4, it is characterised in that the Chinese liquor For 52 degree.
6. a kind of health promoting wine of the improvement cough ant phlegm according to any one of claim 1-4, it is characterised in that the Mel For the acacia honey of fresh refining.
7. a kind of health promoting wine of the improvement cough ant phlegm according to any one of claim 1-4, it is characterised in that preparation method It is as follows:
1) just Saponaria officinalis, Radix Asteriss, Folium Perillae, Radix Peucedani, Radix Glycyrrhizae are clean by weight dries, and is crushed with pulverizer;
2) medical material after above-mentioned crushing is added and is boiled in the container equipped with Chinese liquor, Chinese liquor is 1 with the weight part ratio of medical material:4;
3) boil medical filtration, cooling after 2h, after sterilizing clear liquid;
4) above-mentioned clear liquid is mixed with corresponding weight portion Mel in addition Chinese liquor, sealing obtains final product the health promoting wine after placing 1 month.
8. application of the health promoting wine in cough ant phlegm is improved described in a kind of any one of claim 1-4.
CN201710020647.4A 2017-01-11 2017-01-11 Health wine for improving cough and abundant sputum Withdrawn CN106520486A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6115679A (en) * 1984-06-29 1986-01-23 Itouniuemon Shoten:Kk Production of carbonated alcohol beverage for health
CN101548768A (en) * 2008-06-24 2009-10-07 杨政宽 Health care wine and preparation method thereof
CN102851182A (en) * 2011-06-28 2013-01-02 钱国祥 Citrus grandis health wine for relieving cough due to pathogenic wind-cold
CN104586923A (en) * 2014-12-23 2015-05-06 覃国芳 Medicinal liquor for relieving unknown pyogenic infections and preparation method of medicinal liquor

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6115679A (en) * 1984-06-29 1986-01-23 Itouniuemon Shoten:Kk Production of carbonated alcohol beverage for health
CN101548768A (en) * 2008-06-24 2009-10-07 杨政宽 Health care wine and preparation method thereof
CN102851182A (en) * 2011-06-28 2013-01-02 钱国祥 Citrus grandis health wine for relieving cough due to pathogenic wind-cold
CN104586923A (en) * 2014-12-23 2015-05-06 覃国芳 Medicinal liquor for relieving unknown pyogenic infections and preparation method of medicinal liquor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
袁昌齐,肖正春: "《世界植物药》", 31 December 2012 *

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Application publication date: 20170322