CN106511474A - External traditional Chinese medicine composition with function of removing skin acnes, and skin-care preparation thereof - Google Patents
External traditional Chinese medicine composition with function of removing skin acnes, and skin-care preparation thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention belongs to the cosmetic field, and specifically relates to an external traditional Chinese medicine composition with a function of removing skin acnes, and a skin-care preparation thereof. The external traditional Chinese medicine composition is prepared from flos carthami, radix saposhnikoviae, herba lycopodii, ramulus mori and garden balsam stem. Verification proves that the composition has no irritation on skin. The five kinds of plant components play a synergistic effect; flos carthami and radix saposhnikoviae have effects of promoting blood circulation to remove blood stasis, and smoothening vital energy and blood; herba lycopodii and garden balsam stem can assist the flos carthami and radix saposhnikoviae to play the effect of promoting blood circulation to remove blood stasis; and meanwhile, the ramulus mori can assist the radix saposhnikoviae to play the effects of dispelling wind to relieve exogenous syndrome, clearing away heat and toxic materials, and inducing diuresis to alleviate edema. Sterilizing and inflammation-diminishing factors in the five ingredients can effectively permeate into hair follicle so as to remove acnes by suppressing bacterial growth; and the external traditional Chinese medicine composition has the effects of suppressing acnes, unblocking blocked pores, promoting toxin discharging, and removing acnes.
Description
Technical field
The invention belongs to cosmetic skin field, and in particular to a kind of with the external application Chinese medicine group for dispelling skin acne function
Compound and its skin care formulation.
Background technology
Acne, also known as acne, is a kind of most commonly seen skin disease, and the age has 80% in the crowd between 11～30 years old
People suffers from this disease, is mainly in the position rich in sebaceous glands such as face, back, chest.Acne can with lasting for years, cause appearance damage or
Leave permanent scar and the psychological development to patient causes serious negative effect.Serious acne can cause appearance to be damaged,
More serious negative effect is produced to the psychology and life of patient, anxiety, irritability and not self-confident is shown as, is disturbed normal life
Living and doings, 51.0% patients of college students think that acne affects to choose a job, and university student's patients with acne 59.3% has in various degree
Psychological problems, and wherein have 25% should acceptable learning consulting.Acne is heavier, and the impact to psychology is also bigger.Therefore, for
The study mechanism and solution of acne is received more and more attention.The pathogenesis of acne is the result of multifactor effect,
The factors such as hormonal readiness exception, bacterial overgrowth, heredity, emotional factor, dietary life habits, cosmetics improper use have
Skin acne may be caused.
Traditional Chinese Medicine Theory thinks that the main cause of acne is qi and blood stasis, and lung stomach intrinsic heat, phlegm-blood stasis are gathered.Modern medicine thinks Cuo
The main cause of sore is that smegma is excessive, cuticula hyperplasia, pore group are big, grease blocking pore, propionibacterium acnes exist
Amount reproduction under anoxia condition, causes the generation of inflammation folliculitis, forms acne.
The content of the invention
The technical problem to be solved be to provide it is a kind of natural gentle without any irritating draft skin care formulation,
Skin care formulation is designed from acne Crack cause, using promoting blood circulation and removing blood stasis come qi and blood stasis to the ill, dissipates by dispelling wind and eliminating dampness phlegm-blood stasis
To the greatest extent, removing pattogenic heat from the blood and toxic material from the body alleviates can lung stomach intrinsic heat.Safflower, windproof sharing can make qi and blood smooth with promoting blood circulation and removing blood stasis, lycopodium calvatum, deep
Grass can assist safflower, windproof curative effect promoting blood circulation and removing blood stasis, while ramulus mori assistance is windproof expel pathogenic wind from the body surface, it is clearing heat and detoxicating, and band Li Shui
The effect of detumescence.The inhibiting bacteria and diminishing inflammation factor contained in five things can effectively penetrate into hair follicle, reach anti-acne by suppressing the growth of bacterium
Purpose.Suppress dark sore, dredge blockage pore, promote toxin to discharge, make acne disappear.
The technical problem to be solved is achieved by the following technical programs：
It is a kind of with the external medicine composition for dispelling skin acne function, be made up of the component of following weight：Safflower
20～30 parts, windproof 20～30 parts, 10～20 parts of lycopodium calvatum, 10～20 parts of ramulus mori, 5～10 parts of lopseed.
In above-mentioned composition, safflower, windproof sharing can make qi and blood smooth with promoting blood circulation and removing blood stasis, and lycopodium calvatum, lopseed can be assisted
Safflower, windproof curative effect promoting blood circulation and removing blood stasis are helped, while ramulus mori assistance is windproof expel pathogenic wind from the body surface, it is clearing heat and detoxicating, and the work with inducing diuresis for removing edema
With.The inhibiting bacteria and diminishing inflammation factor contained in five things can effectively penetrate into hair follicle, reach the purpose of anti-acne by suppressing the growth of bacterium.Suppression
Dark sore processed, dredge blockage pore, promote toxin to discharge, make acne disappear.
The preparation method of above-mentioned external medicine composition, step are as follows：
（1）Bulk drug is weighed by the weight of above-mentioned formula；
（2）Extract bulk drug twice with ethanol water that percent by volume is 70%～85%, when extracting for the first time bulk drug with
Ethanol water is with 1g：The solid-liquid ratio mixing of 15 ~ 25ml, heating stirring filtered first after 1.5～3 hours at 55～70 DEG C
The extract of secondary extraction obtains filter residue, is extracted the filter residue for obtaining for the first time with ethanol water with 1g during second extraction：15~
The solid-liquid ratio mixing of 25ml, heating stirring 1.5～3 hours at 55～70 DEG C obtain second extract, merge twice after filtration
Extract obtains external medicine composition crude extract；
（3）The external medicine composition crude extract for obtaining is concentrated into into 0.3～0.5g/ml, concentrate is obtained；
（4）According to 1g：The solid-liquid ratio of 1 ~ 2ml adds propane diols or butanediol in concentrate, at 3500～5500 revs/min
Supernatant liquor is taken after being centrifuged under clock rate degree, suction filtration is collected filtrate and obtains final product external medicine composition.
A kind of skin care formulation for dispelling skin acne containing above-mentioned external medicine composition, is combined by above-mentioned external application Chinese medicine
Thing and skin care item auxiliary material composition.
Further, the skin care formulation is made up of the component of following percentage by weight：
0.01～5% allantoin
1～5% polyalcohol
0.1～1% Sodium Hyaluronate
5～25% external medicine composition
0.01～2% dipotassium glycyrrhizinate
0.01～1% carbomer；
0.003～0.3% organic base；
100% is supplemented to pure water.
Further, the polyalcohol be glycerine, pungent glycol, pentanediol, butanediol, hexanol, in Phenoxyethanol at least
It is a kind of.
Further, the polyalcohol is that glycerine, pungent glycol and pentanediol are combined, the combination of glycerine, pungent glycol and hexanol, fourth
The combination of glycol, pungent glycol and pentanediol, the combination of butanediol, pungent glycol and hexanol, glycerine, pungent glycol, five kinds of combinations of Phenoxyethanol
In one kind.Different polyalcohol collocation are used, and can both play a part of moisturizing, while can play that osmosis is helped, are helped
The various traditional Chinese medicine ingredients of skin absorption are helped, while under the conditions of preservative ingredient is not added, playing anti-corrosion synergistic effect.
Further, the organic base be MEA, diethanol amine, the one kind in triethanolamine.Further, it is described
The preparation method with the external-use skin care preparation for dispelling skin acne function it is as follows,
（1）Each component is weighed by formula consumption；
（2）Reactor is carried out disinfection, the moisture of formula consumption is added, stirring is opened；
（3）Add the allantoin of formula consumption, polyalcohol, Sodium Hyaluronate, dipotassium glycyrrhizinate, in external application successively in a kettle.
Drug composition, persistently stirs 30 minutes to being uniformly dispersed；
（4）Add the carbomer of formula consumption, dispersed with stirring 30 minutes；
（5）Dispersion is complete, adds the organic base of formula consumption, and pH value is transferred to 5.3～5.8, and neutralization carbomer is to gel
State, obtains the skin care formulation of gel state.
The present invention has the advantages that：
The present invention forms most the underlying cause from acne and starts with, the ratio of science five kinds of Chinese medicinal plant compositions of collocation, synergy,
Safflower, windproof sharing can make qi and blood smooth with promoting blood circulation and removing blood stasis, and lycopodium calvatum, lopseed can assist safflower, windproof promoting blood circulation and removing blood stasis
Curative effect, while ramulus mori assistance is windproof expel pathogenic wind from the body surface, it is clearing heat and detoxicating, and the effect with inducing diuresis for removing edema.What is contained in five things antibacterial disappears
The scorching factor can effectively penetrate into hair follicle, reach the purpose of anti-acne by suppressing the growth of bacterium.Suppress dark sore, dredge blockage pore,
Promote toxin to discharge, make acne disappear.Various polyalcohol collocation in skin care formulation are used, and play both moisturizings, while helping infiltration to make
With, the various traditional Chinese medicine ingredients of skin absorption are helped, while under the conditions of preservative ingredient is not added, anti-corrosion synergistic effect is played,
Avoid the stimulation to acne skin using the conventional preservatives used in cosmetics, the gentle removing acne of safety, non-stimulated nothing
Toxic and side effect.
Specific embodiment
With reference to embodiment, the present invention will be described in detail, and embodiment is only the preferred embodiment of the present invention,
It is not limitation of the invention.
Embodiment 1
The preparation of external medicine composition：
（1）Bulk drug is weighed by weight ratio：Safflower 20, windproof 20 parts, 20 parts of lycopodium calvatum, 20 parts of ramulus mori, lopseed 7.5
Part；
（2）Bulk drug is extracted twice with the ethanol water that percent by volume is 80%, bulk drug and ethanol water when extracting for the first time
Solution is with 1g：The solid-liquid ratio mixing of 20ml, heating stirring 2 hours at 60 DEG C are filtered the extract for extracting for the first time and are filtered
Slag, is extracted the filter residue for obtaining with ethanol water for the first time with 1g during second extraction：The solid-liquid ratio mixing of 15ml, at 60 DEG C
Lower heating stirring 3 hours, obtains second extract after filtration, merge extract twice and obtain external medicine composition crude extract；
（3）By the external medicine composition crude extract for obtaining, 0.5g/ml is concentrated into, concentrate is obtained；
（4）According to 1g：The solid-liquid ratio of 1ml adds propane diols in concentrate, after 3500～5500 revs/min of centrifugations
Supernatant liquor is taken, suction filtration is collected filtrate and obtains final product external medicine composition.
Table one：Gel formula is constituted
Process for preparing hydrogels is as follows：
（1）Each component is weighed by formula consumption；
（2）Reactor is carried out disinfection, the moisture of formula consumption is added, stirring is opened；
（3）Add the allantoin of formula consumption, polyalcohol, Sodium Hyaluronate, dipotassium glycyrrhizinate, in external application successively in a kettle.
Drug composition, persistently stirs 30 minutes to being uniformly dispersed；
（4）Add the carbomer of formula consumption, dispersed with stirring 30 minutes；
（5）Dispersion is complete, adds the organic base of formula consumption, and pH value is transferred to 5.3 ~ 5.8, and neutralization carbomer is to gel
State, obtains the skin care formulation of gel state.
The clinical trial data of embodiment 1：
Product removing acne clinical trial data：
Acne gel dispel for clinical and commercially available go acne products to carry out contrast test, blank group by prepared by embodiment 2,3,4
Not use any product for resolving poxes.Test product is used after the daily face cleaning of tester, daily sooner or later using twice.Tester is in
0 day, the 7th day, the 14th day, the 28th day content with Visia skin detection Instrument measurings acne sites skin oil and fat, acne sites
Melanin content, acne inflammatory factor burst size.Simultaneously tester needs self-assessment to dispel acne anti-inflammatory situation, and pore shrinks effect
Really, the use feeling such as glossy reduction situation of skin.
Test result such as following table one：
From one test result of table, the present invention has the skin-care gel for removing acne function, in acne eradicating efficacy, skin oil
Light is reduced, acne print fading effect, and pore shrinks situation, and antioxygen is releived effect, is substantially better than commercially available product in terms of salubrious assimilation effect
Product.Permanence operation is also substantially better than commercially available simultaneously.Go acne products effect also better than commercially available prod, especially disappear in acne
Releive the aspects such as effect except effect, the glossy reduction of skin, acne print fading effect, pore shrink situation, antioxygen.
In sum, the present invention based on the research of pathogenesis of acne mechanism and clinical manifestation, dispel acne and be by science
Objective, science compound five kinds of plant components, and the skin care item adjunct ingredient allotment that moisturizing of arranging in pairs or groups is releived is formed.What the present invention was provided goes
Except the gel of acne, also with antiallergic anti-inflammatory, effect of acne print is desalinated in oil-control exfoliating, is realized to acne by number of ways
Effectively treatment, and have no toxic side effect and skin irritation.
Above example only expresses embodiments of the present invention, and its description is more concrete and detailed, but it is not intended that
Restriction to inventing, as long as the technical scheme obtained by the way of equivalent or equivalent transformation, all should fall in the present invention
Protection domain within.
Claims (7)
1. it is a kind of with the external medicine composition for dispelling skin acne function, it is characterised in that the composition is by weighing as follows
The component composition of amount part proportioning：
20～30 parts of safflower, windproof 20～30 parts, 10～20 parts of lycopodium calvatum, 10～20 parts of ramulus mori, 5～10 parts of lopseed.
2. the preparation method with the external medicine composition for dispelling skin acne function described in a kind of claim 1, which is special
Levy and be：
（1）Weight as described in claim 1 weighs bulk drug；
（2）Extract bulk drug twice with ethanol water that percent by volume is 70%～85%, when extracting for the first time bulk drug with
Ethanol water is with 1g：The solid-liquid ratio mixing of 15 ~ 25ml, heating stirring filtered first after 1.5～3 hours at 55～70 DEG C
The extract of secondary extraction obtains filter residue, is extracted the filter residue for obtaining for the first time with ethanol water with 1g during second extraction：15~
The solid-liquid ratio mixing of 25ml, heating stirring 1.5～3 hours at 55～70 DEG C obtain second extract, merge twice after filtration
Extract obtains external medicine composition crude extract；
（3）The external medicine composition crude extract for obtaining is concentrated into into 0.3～0.5g/ml, concentrate is obtained；
（4）According to 1g：The solid-liquid ratio of 1 ~ 2ml adds propane diols or butanediol in concentrate, at 3500～5500 revs/min
Supernatant liquor is taken after being centrifuged under clock rate degree, suction filtration is collected filtrate and obtains final product external medicine composition.
3. it is a kind of with the external-use skin care preparation for dispelling skin acne function, it is characterised in that the skin care formulation will by right
Ask the external medicine composition and skin care item auxiliary material composition described in 1, component group of the skin care formulation by following percentage by weight
Into：
0.01～5% allantoin；
1～5% polyalcohol；
0.1～1% Sodium Hyaluronate；
5～25% external medicine composition；
0.01～2% dipotassium glycyrrhizinate；
0.01～1% carbomer；
0.003～0.3% organic base；
100% is supplemented to pure water.
4. it is according to claim 3 with the external-use skin care preparation for dispelling skin acne function, it is characterised in that described many
First alcohol is glycerine, pungent glycol, pentanediol, butanediol, hexanol, at least one in Phenoxyethanol.
5. it is according to claim 3 with the external-use skin care preparation for dispelling skin acne function, it is characterised in that described many
First alcohol is that glycerine, pungent glycol and pentanediol are combined, the combination of glycerine, pungent glycol and hexanol, butanediol, pungent glycol and pentanediol group
Close, the combination of butanediol, pungent glycol and hexanol, glycerine, pungent glycol, Phenoxyethanol combination, the one kind in five kinds of combinations.
6. it is according to claim 3 with the external-use skin care preparation for dispelling skin acne function, it is characterised in that described to have
Machine alkali is MEA, diethanol amine, the one kind in triethanolamine.
7. the preparation method with the external-use skin care preparation for dispelling skin acne function described in a kind of claim 3, its feature
It is：
（1）Each component is weighed by formula consumption；
（2）Reactor is carried out disinfection, the moisture of formula consumption is added, stirring is opened；
（3）Add the allantoin of formula consumption, polyalcohol, Sodium Hyaluronate, dipotassium glycyrrhizinate, in external application successively in a kettle.
Drug composition, persistently stirs 30 minutes to being uniformly dispersed；
（4）Add the carbomer of formula consumption, dispersed with stirring 30 minutes；
（5）Dispersion is complete, adds the organic base of formula consumption, and pH value is transferred to 5.3～5.8, and neutralization carbomer is to gel
State, obtains the skin care formulation of gel state.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610999880.7A CN106511474A (en) | 2016-11-14 | 2016-11-14 | External traditional Chinese medicine composition with function of removing skin acnes, and skin-care preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610999880.7A CN106511474A (en) | 2016-11-14 | 2016-11-14 | External traditional Chinese medicine composition with function of removing skin acnes, and skin-care preparation thereof |
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| Publication Number | Publication Date |
|---|---|
| CN106511474A true CN106511474A (en) | 2017-03-22 |
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|---|---|---|---|
| CN201610999880.7A Withdrawn CN106511474A (en) | 2016-11-14 | 2016-11-14 | External traditional Chinese medicine composition with function of removing skin acnes, and skin-care preparation thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107334845A (en) * | 2017-07-12 | 2017-11-10 | 山东省中医药研究院 | A kind of acne gel containing traditional Chinese medicine ingredients and preparation method thereof |
| CN110302267A (en) * | 2019-06-13 | 2019-10-08 | 李时珍医药集团有限公司 | A kind of Chinese medicine anti-acne composition and preparation method thereof |
| CN110694015A (en) * | 2019-10-09 | 2020-01-17 | 江苏省中医院 | Acne removing gel and preparation method thereof |
-
2016
- 2016-11-14 CN CN201610999880.7A patent/CN106511474A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107334845A (en) * | 2017-07-12 | 2017-11-10 | 山东省中医药研究院 | A kind of acne gel containing traditional Chinese medicine ingredients and preparation method thereof |
| CN110302267A (en) * | 2019-06-13 | 2019-10-08 | 李时珍医药集团有限公司 | A kind of Chinese medicine anti-acne composition and preparation method thereof |
| CN110694015A (en) * | 2019-10-09 | 2020-01-17 | 江苏省中医院 | Acne removing gel and preparation method thereof |
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