CN106511146A - Gel with efficacies of inhibiting bacteria, preserving moisture and nourishing skin and preparation method of gel - Google Patents

Gel with efficacies of inhibiting bacteria, preserving moisture and nourishing skin and preparation method of gel Download PDF

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Publication number
CN106511146A
CN106511146A CN201510571406.XA CN201510571406A CN106511146A CN 106511146 A CN106511146 A CN 106511146A CN 201510571406 A CN201510571406 A CN 201510571406A CN 106511146 A CN106511146 A CN 106511146A
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China
Prior art keywords
gel
skin
moisturizing skin
complexion improving
carrying
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Pending
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CN201510571406.XA
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Chinese (zh)
Inventor
史立秀
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Eupatorium Biotechnology (shanghai) Limited-Liability Co
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Eupatorium Biotechnology (shanghai) Limited-Liability Co
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Priority to CN201510571406.XA priority Critical patent/CN106511146A/en
Publication of CN106511146A publication Critical patent/CN106511146A/en
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Abstract

The invention discloses gel with the efficacies of inhibiting bacteria, preserving moisture and nourishing skin and a preparation method of the gel. The preparation method of the gel with the efficacies of inhibiting bacteria, preserving moisture and nourishing skin comprises the following steps: taking herba eupatorii distillate, deionized water, glycerinum and propylene glycol, sequentially feeding the components into a stirring kettle, carrying out heating till the temperature is 90 DEG C, carrying out standing for 20min under the thermal insulation state, carrying out sterilization, carrying out cooling under stirring till the temperature is 60 DEG C, feeding sodium hyaluronate and carbomer resin into a system, carrying out uniform mixing, carrying out further cooling under stirring till the temperature is 40 DEG C, feeding herba eupatorii volatile oil and triethanolamine into the system, carrying out further stirring for 10min, and after stopping stirring, carrying out cooling till the temperature is the room temperature, thus obtaining the gel with the efficacies of inhibiting bacteria, preserving moisture and nourishing skin. The active ingredient of the gel is derived from the plant herba eupatorii with the herbal medicinal fragrance, and the gel has the functions of inhibiting breeding of bacteria on the skin and preserving moisture, is convenient to use, and free of toxic and side effects, and has the pleasant herbal medicinal fragrance.

Description

A kind of antibacterial moisturizing skin and complexion improving gel and preparation method thereof
Technical field
The invention belongs to natural product applied technical field, more particularly to a kind of antibacterial moisturizing skin and complexion improving gel being prepared from according to Chinese medicine and preparation method thereof.
Background technology
Medicated incense plant is the plant group for having medicinal plants and spice berry predicable concurrently, and the medicinal ingredient containing the volatile ingredient with special aromatic odor and macromole, with characteristics such as armaticity, medical, antioxidation, antibacterials.
The earliest medical book in the world《Huang di's Canon of Medicine》And earliest pharmacopeia《Compendium of Materia Medica》On the books, medicated incense vegetable oil is in the therapeutic efficiency for having uniqueness to aspects such as skin, internal organs, endocrine, muscle, meridians.
Most of active component contained by medicated incense plant is all beneficial to the body health of people, plant extract is applied to skin protection two advantages for being substantially better than general chemical skin protection, that is homology and natural sex, plant extract because its ingredient mostly with body material " homologous ", will not be treated as " invader " by the immune system of human body, more importantly, even if medicated incense active components of plants can not be fully absorbed by body, also can excrete under normal metabolism, will not residue in and work the mischief in vivo or damage, therefore the plant extract for combining through appropriate effect can effectively skin nutrition, safeguard the health of skin.
At present, a large amount of chemical compositions using from Coal Chemical Industry or petrochemical industry in many cosmetics or cosmetics of everyday use, it is easily caused exogenous " foreign body " accumulation to discharge in vivo, affect the immunologic function of body, easily cause anaphylaxiss and cause the damage of skin, such as redness, prurituss, red blood streak etc..And the raw material of plant skin protection comes from the product of the Nature, it is the maintenance composition needed for skin health without artificial chemical composition, the alcohols contained in plant, esters, saccharide etc., can be secreted with balanced skin oil and fat, keeps the aqueous degree of skin;Balance skin microcirculation, is conducive to the healing of minimally invasive skin;Antibacterial bacteriostatic, protects skin health simultaneously.
The content of the invention
In order to solve the problems of the prior art, it is an object of the invention to provide have suppress skin bacterium to grow and moisture-keeping function, it is easy to use, have no toxic side effect, the antibacterial moisturizing skin and complexion improving gel that medicated incense is pleasant.
For achieving the above object, the present invention is employed the following technical solutions:The component and the weight portion of correspondence component that a kind of antibacterial moisturizing skin and complexion improving gel is included is as follows:
20 weight portion of Herba Eupatorii distillate,
55.8 weight portion of deionized water,
13 weight portion of glycerol,
10 weight portion of Propylene Glycol.
The present invention working mechanism be:The volatile oil of natural medicated incense plant is mostly from its fruit, flower, leaf, root or seed etc. with extraction by steam distillation, main composition includes terpenes, alcohols, phenolic compound, volatile micromolecular compound is, the effects such as with antibacterial, antivirus, dispelling abnormal flavor.The present invention prepares a kind of antibacterial moisturizing skin and complexion improving gel with the medicated incense plant Herba Eupatorii of pure natural as primary raw material using the pleasant characteristic of the antibacterial of its extract, antiviral, medicated incense.
Herba Eupatorii has suppression killing action containing main components such as caryophyllene, mono- bisabolenes of β, alpha-terpineol, cymol, acetic acid orange alcohol ester, thymol methyl ethers to candida albicanses, diphtheria corynebacterium, staphylococcus aureuses, sarcina, Bacillus proteuss etc..
The antibacterial moisturizing skin and complexion improving gel also includes 0.3 weight portion of card ripple.
The antibacterial moisturizing skin and complexion improving gel also includes 0.2 weight portion of hyaluronate sodium.
The antibacterial moisturizing skin and complexion improving gel also includes 0.4 weight portion of volatile oil of Herba Eupatorii.
The antibacterial moisturizing skin and complexion improving gel also includes 0.3 weight portion of triethanolamine.
The antibacterial moisturizing skin and complexion improving gel also includes 0.3 weight portion of card ripple, 0.2 weight portion of hyaluronate sodium, 0.4 weight portion of volatile oil of Herba Eupatorii, 0.3 weight portion of triethanolamine.
Gel of the present invention adds the auxiliary materials such as thickening agent to be formulated using Herba Eupatorii distillate as carrier with volatile oil of Herba Eupatorii as main antibacterial skin and complexion improving composition.
Another object of the present invention is to provide a kind of preparation method of antibacterial moisturizing skin and complexion improving gel, and its preparation method comprises the steps:
Take Herba Eupatorii distillate, deionized water, glycerol and Propylene Glycol to be put in stirred tank one by one, temperature is then heated to for 90 DEG C, stand insulation 20min sterilizings, then 60 DEG C are cooled to while stirring, by mix homogeneously in hyaluronate sodium input system, are continued stirring and are cooled to 40 DEG C, by in volatile oil of Herba Eupatorii and triethanolamine respectively input system, continue stirring 10min, stop stirring, be cooled to room temperature and obtain final product the antibacterial moisturizing skin and complexion improving gel.
Compared with prior art, the present invention has following beneficial effect:
1st, compared with existing skin-care gel at present on the market, the main composition of the skin-care gel of the present invention is from natural medicated incense plant-Herba Eupatorii, medicinal ingredient contained by which such as terpenes containing oxygen derivative, sesquiterpenoid etc. are compound of the carbon number less than 16, high volatility, with very strong bactericidal function, the growth and breeding of skin surface antibacterial can effectively be suppressed, with highly effective and safe, abnormal smells from the patient is pleasant the features such as.
2nd, aromatic odor can regulate and control blood circulation and Lymph microcirculation, improve skin-nourishing and metabolic function, healthy skin via the olfactory stimulation of people human nerve-endocrine network.
3rd, the setting of preparation method fully ensures that the retention of effective ingredient, takes the principle of " addition of substep temperature control ", the water soluble ingredient of plant is separated with volatile ingredient, is added at different temperatures, fully retains and play the overall efficacy of plant extract.
Specific embodiment
With reference to specific embodiment, the present invention is described in detail.Following examples will be helpful to those skilled in the art and further understand the present invention, but the invention is not limited in any way.It should be pointed out that to those skilled in the art, without departing from the inventive concept of the premise, that what is made some belongs to protection scope of the present invention without substantial modified or deformation.
The present invention the volatile oil of Herba Eupatorii and the preparation method of distillate be:Dried plant material Herba Eupatorii 150g is weighed, is put in 2000mL flasks, add water 1000mL, connection condensing units and oil water separator, heating extraction 80-120 minute, stop distillation when not being further added by quintessence oil layer, separate volatile oil and distillate, volatile oil is with standby after anhydrous sodium sulfate drying 10h.
It is specifically shown in following embodiment:
Embodiment 1
Take Herba Eupatorii distillate, deionized water, glycerol and Propylene Glycol to be put in stirred tank one by one, temperature is then heated to for 90 DEG C, stand insulation 20min sterilizings, be then cooled to room temperature while stirring and obtain final product antibacterial moisturizing skin and complexion improving gel.The component that the antibacterial moisturizing skin and complexion improving gel is included be 20 grams of Herba Eupatorii distillate, 55.8 grams of deionized water, 13 grams of glycerol, 10 grams of Propylene Glycol.
The Inhibition test of 4 kinds of antibacterials is carried out to the antibacterial moisturizing skin and complexion improving gel of Herba Eupatorii of the present embodiment, it is as follows:
Filter paper enzyme determines fungistatic effect.The filter paper of a diameter of 7mm is got with card punch, is dried in being placed on 60 DEG C of drying baker after autoclaving, is fully soaked in putting it into test sample liquid before experiment.The culture of different strain is diluted to into the 10-4 of original content, respectively take 20 μ l diluents to be uniformly coated onto in the solid medium of a diameter of 85mm, then tape test sample liquid filter paper is attached on flat board, cultivate 24 h in 37 DEG C of constant incubators, the diameter of inhibition zone is determined, in triplicate.Test result is:Epidermis Portugal coccus 8.8 ± 0.1, escherichia coli 10.3 ± 0.2, golden yellow Portugal coccus 11.1 ± 0.1, Candida albicans 9.7 ± 0.1.
Embodiment 2
Take Herba Eupatorii distillate, deionized water, glycerol and Propylene Glycol to be put in stirred tank one by one, temperature is then heated to for 90 DEG C, stand insulation 20min sterilizings, then 60 DEG C are cooled to while stirring, mix homogeneously in hyaluronate sodium input system, continuation stirring are cooled to room temperature and obtain final product antibacterial moisturizing skin and complexion improving gel.The component that the antibacterial moisturizing skin and complexion improving gel is included is as follows:20 grams of Herba Eupatorii distillate, 55.8 grams of deionized water, 13 grams of glycerol, 10 grams of Propylene Glycol, 0.2 gram of hyaluronate sodium.
Embodiment 3
Take Herba Eupatorii distillate, deionized water, glycerol and Propylene Glycol to be put in stirred tank one by one, temperature is then heated to for 90 DEG C, stand insulation 20min sterilizings, then 60 DEG C are cooled to while stirring, mix homogeneously in hyaluronate sodium and carbomer input system, continuation stirring are cooled to room temperature and obtain final product antibacterial moisturizing skin and complexion improving gel.The component that the antibacterial moisturizing skin and complexion improving gel is included is as follows:20 grams of Herba Eupatorii distillate, 55.8 grams of deionized water, 13 grams of glycerol, 10 grams of Propylene Glycol, 0.3 gram of card ripple, 0.2 gram of hyaluronate sodium.
Embodiment 4
Take Herba Eupatorii distillate, deionized water, glycerol and Propylene Glycol to be put in stirred tank one by one, temperature is then heated to for 90 DEG C, stand insulation 20min sterilizings, then 60 DEG C are cooled to while stirring, by mix homogeneously in hyaluronate sodium and carbomer input system, are continued stirring and are cooled to 40 DEG C, by in volatile oil of Herba Eupatorii input system, continue stirring 10min, stop stirring, be cooled to room temperature and obtain final product antibacterial moisturizing skin and complexion improving gel.The component that the antibacterial moisturizing skin and complexion improving gel is included is as follows:20 grams of Herba Eupatorii distillate, 55.8 grams of deionized water, 13 grams of glycerol, 10 grams of Propylene Glycol, 0.3 gram of card ripple, 0.2 gram of hyaluronate sodium, 0.4 gram of volatile oil of Herba Eupatorii.
Embodiment 5
Take Herba Eupatorii distillate, deionized water, glycerol and Propylene Glycol to be put in stirred tank one by one, temperature is then heated to for 90 DEG C, stand insulation 20min sterilizings, then 60 DEG C are cooled to while stirring, by mix homogeneously in hyaluronate sodium and carbomer input system, are continued stirring and are cooled to 40 DEG C, by in volatile oil of Herba Eupatorii and triethanolamine respectively input system, continue stirring 10min, stop stirring, be cooled to room temperature and obtain final product antibacterial moisturizing skin and complexion improving gel.The component that the antibacterial moisturizing skin and complexion improving gel is included is as follows:20 grams of Herba Eupatorii distillate, 55.8 grams of deionized water, 13 grams of glycerol, 10 grams of Propylene Glycol, 0.3 gram of card ripple, 0.2 gram of hyaluronate sodium, 0.4 gram of volatile oil of Herba Eupatorii, 0.3 gram of triethanolamine.
Moistening effect test is carried out to the antibacterial moisturizing skin and complexion improving gel of Herba Eupatorii of the present embodiment, it is as follows:
Using CornermeterCM825 test systems, skin hydration state is tested, skin hydration state change reflects the change of skin moisture content, and its value is bigger, and moisture is higher, thus be accordingly used in evaluation skin moisture-keeping situation.30 19~22 years old women's health experimenters are recruited, without skin or systemic disease history, and tested period does not smear any with the unrelated skin care item of experiment.Test site room temperature (25 ± 1) DEG C, relative humidity (40 ± 5) %, wiped after experimenter's both arms using 36 DEG C or so of clear water, in experimenter's inboard arm away from labelling tested region (2cm × 12cm) at 5 cm of palm base portion, after 30 min that sit quietly under test environment, start test.By the Herba Eupatorii prepared in embodiment antibacterial moisturizing skin and complexion improving gel and blank without fragrant gel, 500 μ L sample liquid are smeared in tested region respectively, determine the skin hydration state value in tested region in 1,2,3,4 h.All experimental datas are gathered after instrument obtains stabilization signal, using the meansigma methodss of 6 readings as measured value, carry out data analysiss using SPSS17.0 softwares, compare and checked using t between group, P<0.05 has statistical significance.Test result indicate that:Compared with blank district, the hydration status of the skin in the tested area of sample are obviously improved (P<0.05), illustrate that the antibacterial moisturizing skin and complexion improving gel of Herba Eupatorii has good moistening effect.
In sum, distillate of the present invention based on the volatility medicinal ingredient quintessence oil and non-volatile component of medicated incense plant Herba Eupatorii carries out scientific compatibility, epidermis Portugal coccus, escherichia coli, golden yellow Portugal coccus, Candida albicans that skin readily accesses etc. can effectively be suppressed, and skin hydration state can be significantly improved, lift skin moisture-keeping ability, the skin and complexion improving effect with antibacterial, moisturizing.
Above the specific embodiment of the present invention is described.It is to be appreciated that the invention is not limited in above-mentioned particular implementation, those skilled in the art can make various modifications or modification within the scope of the claims, and this has no effect on the flesh and blood of the present invention.

Claims (7)

1. a kind of antibacterial moisturizing skin and complexion improving gel, it is characterised in that:The component and the weight portion of correspondence component that the antibacterial moisturizing skin and complexion improving gel is included is as follows:
Herba Eupatorii distillate 20 weight portions,
Deionized water 55.8 weight portion,
Glycerol 13 weight portions,
Propylene Glycol 10 weight portions.
2. a kind of antibacterial moisturizing skin and complexion improving gel as claimed in claim 1, it is characterised in that:The antibacterial moisturizing skin and complexion improving gel also includes 0.3 weight portion of card ripple.
3. a kind of antibacterial moisturizing skin and complexion improving gel as claimed in claim 1, it is characterised in that:The antibacterial moisturizing skin and complexion improving gel also includes 0.2 weight portion of hyaluronate sodium.
4. a kind of antibacterial moisturizing skin and complexion improving gel as claimed in claim 1, it is characterised in that:The antibacterial moisturizing skin and complexion improving gel also includes 0.4 weight portion of volatile oil of Herba Eupatorii.
5. a kind of antibacterial moisturizing skin and complexion improving gel as claimed in claim 1, it is characterised in that:The antibacterial moisturizing skin and complexion improving gel also includes 0.3 weight portion of triethanolamine.
6. a kind of antibacterial moisturizing skin and complexion improving gel as claimed in claim 1, it is characterised in that:The antibacterial moisturizing skin and complexion improving gel also includes 0.3 weight portion of card ripple, 0.2 weight portion of hyaluronate sodium, 0.4 weight portion of volatile oil of Herba Eupatorii, 0.3 weight portion of triethanolamine.
7. a kind of preparation method of antibacterial moisturizing skin and complexion improving gel, it is characterised in that:The preparation method comprises the steps:
Take Herba Eupatorii distillate, deionized water, glycerol and Propylene Glycol to be put in stirred tank one by one, temperature is then heated to for 90 DEG C, stand insulation 20min sterilizings, then 60 DEG C are cooled to while stirring, by mix homogeneously in hyaluronate sodium input system, are continued stirring and are cooled to 40 DEG C, by in volatile oil of Herba Eupatorii and triethanolamine respectively input system, continue stirring 10min, stop stirring, be cooled to room temperature and obtain final product the antibacterial moisturizing skin and complexion improving gel.
CN201510571406.XA 2015-09-09 2015-09-09 Gel with efficacies of inhibiting bacteria, preserving moisture and nourishing skin and preparation method of gel Pending CN106511146A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108158977A (en) * 2018-02-02 2018-06-15 上海哈美实业发展有限公司 A kind of private parts traditional Chinese medicine gel and preparation method thereof
CN111419741A (en) * 2020-04-13 2020-07-17 青岛智博生物科技有限公司 Plant essential oil hyaluronic acid stock solution antibacterial gel and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103263679A (en) * 2013-05-02 2013-08-28 上海交通大学 Drug-smelling plant air clean fluid for purifying environment and reinforcing respiratory system
CN104490703A (en) * 2014-12-24 2015-04-08 广州丹奇日用化工厂有限公司 Moisture retention and skin whitening cosmetic composition and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103263679A (en) * 2013-05-02 2013-08-28 上海交通大学 Drug-smelling plant air clean fluid for purifying environment and reinforcing respiratory system
CN104490703A (en) * 2014-12-24 2015-04-08 广州丹奇日用化工厂有限公司 Moisture retention and skin whitening cosmetic composition and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108158977A (en) * 2018-02-02 2018-06-15 上海哈美实业发展有限公司 A kind of private parts traditional Chinese medicine gel and preparation method thereof
CN111419741A (en) * 2020-04-13 2020-07-17 青岛智博生物科技有限公司 Plant essential oil hyaluronic acid stock solution antibacterial gel and preparation method and application thereof

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Application publication date: 20170322

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