CN105726448B - A kind of skin care item and preparation method thereof of the honeycomb active constituent containing there are many - Google Patents
A kind of skin care item and preparation method thereof of the honeycomb active constituent containing there are many Download PDFInfo
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- CN105726448B CN105726448B CN201610231960.8A CN201610231960A CN105726448B CN 105726448 B CN105726448 B CN 105726448B CN 201610231960 A CN201610231960 A CN 201610231960A CN 105726448 B CN105726448 B CN 105726448B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
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Abstract
The present invention provides a kind of skin care item and preparation method thereof of the honeycomb active constituent containing there are many, and the honeycomb compositions for being 1~3% containing mass percentage in the skin care item, the honeycomb compositions include each component of following mass parts：10~40 parts of Mel extract, 10~40 parts of royal jelly, 10~40 parts of honey, 10~40 parts of propolis extract.Skin care item provided by the invention have good moistening effect and safety, skin sense good.
Description
Technical field
The invention belongs to cosmetic technical field, more particularly to it is a kind of containing there are many skin care item of honeycomb active constituent and its
Preparation method.
Background technology
As the improvement of people's living standards, the requirement to cosmetics is also higher and higher, good shield is not only required
Skin beauty functions, but also require Product quality and safety, irritation small.Both however existing skin care item, it tends to be difficult to take into account.
Foundation cream is one of common cosmetics and skincare product of people, and people often reach the purpose of skin care, repair face, isolation by smearing foundation cream.
However, due to the characteristic of foundation formulas, existing foundation product is often in moisturizing antiphlogistic effects, safety, skin sense and patch skin etc.
Aspect, which remains, need to improve place.
Invention content
The present invention is to make up the deficiencies in the prior art, is provided a kind of good with good moistening effect, safety and skin sense
Containing there are many honeycomb active constituent skin care item and preparation method thereof.
The present invention is to reach its purpose, as follows using technical solution：
It is a kind of containing there are many skin care item of honeycomb active constituent, containing mass percentage be 1~3% in the skin care item
Honeycomb compositions, the honeycomb compositions include each component of following mass parts：10~40 parts of Mel extract, royal jelly 10
~40 parts, 10~40 parts of honey, 10~40 parts of propolis extract.
Also containing the following each component of mass percentage in the skin care item：It is isohexadecane 3.0%~5.0%, different hard
Resin acid isopropyl ester 1.0%~5.0%, isooctadecanol isostearate 1.0%~3.0%, methyl sesquistearate
1.0%~1.5%, caprylic/capric triglyceride 1.0%~6.0%, butanediol 2.0%~8.0%, PEG-20 methyls
Sesquistearate 0.8%~1.5%, xanthans 0.02%~0.3%, glucan 0.5%~3.0%, panthenol 0.5%~
3.0%, bisabolol 0.1%~0.5%.
Also contain colorant 2%~8% in the skin care item.Further, the colorant is specially in foundation product
Allow the colorant used, for example, titanium dioxide, CI 77491, CI 77499, CI 77492 etc..As a kind of specific reality
Mode is applied, colorant is grouped as by the following each group of the mass percentage in skin care item：Titanium dioxide 2.0%~7.0%,
CI 774910.02%~0.3%, CI 77,499 0.02%~0.2%, CI 77,492 0.02%~0.3%.
Also contain preservative 0.1%~0.8% in the skin care item.
The skin care item are foundation cream.
The skin care item are grouped as by each group of following mass percentage：1~3% honeycomb compositions, isohexadecane
3.0%~5.0%, isopropyl isostearate 1.0%~5.0%, isooctadecanol isostearate 1.0%~3.0%, methyl Portugal
Sugared sesquistearate 1.0%~1.5%, caprylic/capric triglyceride 1.0%~6.0%, butanediol 2.0%~8.0%,
PEG-20 methyls sesquistearate 0.8%~1.5%, xanthans 0.02%~0.3%, glucan 0.5%~
3.0%, panthenol 0.5%~3.0%, bisabolol 0.1%~0.5%, colorant 2%~8%, preservative 0.1~0.8%,
The water of surplus.
The present invention also provides a kind of preparation methods of the skin care item of honeycomb active constituent containing there are many described above, including
Following steps：
1) each component is weighed according to formula, the formula includes each component of following mass percentage：1~3% bee
Nest composition, isohexadecane 3.0%~5.0%, isopropyl isostearate 1.0%~5.0%, isooctadecanol isostearate
1.0%~3.0%, methyl sesquistearate 1.0%~1.5%, caprylic/capric triglyceride 1.0%~6.0%,
Butanediol 2.0%~8.0%, PEG-20 methyls sesquistearate 0.8%~1.5%, xanthans 0.02%~
0.3%, glucan 0.5%~3.0%, panthenol 0.5%~3.0%, bisabolol 0.1%~0.5%, colorant 2%~
8%, preservative 0.1~0.8%, surplus water；
2) xanthans is soaked with butanediol, is then added in water phase pot, PEG-20 methyl times semihards are added in stirring
Resin acid ester, water are warming up to 75~85 DEG C, and heat preservation is spare as B phases until being completely dissolved；
3) B phases obtained by step 2) are emulsified by vacuum suck in pot, homogeneous；
4) by colorant, isohexadecane, isopropyl isostearate, isooctadecanol isostearate, methyl times semihard
Resin acid ester, caprylic/capric triglyceride sequentially add in oil phase pot, are then heated to 75~85 DEG C, as A phases, then by A phases
It is emulsified in pot by vacuum suck, stirring, homogeneous are cooled to 40~50 DEG C；
5) glucan, panthenol are added in emulsification pot, stir evenly, remaining components are then added, continues to stir；
6) 38 DEG C are cooled to hereinafter, discharging.
Technical solution provided by the invention has the advantages that：
In skin care item provided by the invention, contain by Mel extract, royal jelly, honey, propolis extract according to specific
The honeycomb compositions of composition are matched, each component interacts in the honeycomb compositions, synergistic, plays moisturizing to skin, resists
It is scorching, releive, antibacterial the effect of, and it is natural origin, safe, without any side effects.On the one hand it can improve moisture of skin tune
Function is saved, good moistening effect is provided for keratoderma, increases skin elasticity and flexibility；On the other hand it can play anti-
The anti-infection of bacterium, plays anti-inflammatory effect.
It is as follows to several components descriptions for being added of skin care item of the present invention below：
Mel extract, chemical composition contain abundant amino acid, polysaccharide liquid, lactic acid, urea etc..The skin care of the present invention
The Mel extract added in product can be bought by market and be obtained, using Spain Cobiosa public affairs in the embodiment of the present invention
The BIO-HYDRACTYL (Mel extract) of department.
Royal jelly also known as bee milk, honeybee royal breast, queen bee breast, royal jelly, are the young worker bee pharynxes that larva is cultivated in honeycomb
The secretion of gland is supplied with the food for the larva that will become queen bee and the food that queen bee is lifelong.It is obtained by market purchase
.Contain multivitamin, sugar, protein, lipid, minerals.In the prior art, royal jelly can be made as follows
It is standby：Produce royal jelly 48~72h should carry out after moving worm, pulp production group be checked, as wax cup makes royal cell, larva therein by worker bee
Also it has grown up, you can with slurry.Take slurry that should wear work clothes in clean indoor progress, wear masks.Each section of lath is first removed, use is small
Tweezers remove larva, then dig out royal jelly, are immediately placed in amber glass bottle, closed, deepfreeze.Super oxygen in royal jelly
Object mutase (SOD) is oxidation resistant main component.It there is very strong effect, royal jelly to have the reparation and regeneration of cell
Antibacterial and to wound infection have the function of promote healing.Experiments have shown that the antimicrobial spectrum of royal jelly is Escherichia coli, golden yellow Portugal
Grape ball typhoid bacillus, streptococcus, proteus, hay bacillus, tubercle bacillus, starlike trichophyte and Epidermophyton etc..Royal jelly
Containing proteohormone and natural antibiotics, can be played when smearing treatment scald prevents infection, promote Hemapoiesis, more after do not stay scar
The effect of trace.The ACNACIDOL (royal jelly) for using French Vincience companies to provide in the embodiment of the present invention.
Honey：It is the nectar that honeybee is adopted from the flowering plant's flowers.Honeybee takes the water content to be about from the spending of plant
75% nectar or secretion, it contains a large amount of sugared part, amino acid, several mineral materials etc..Honey is to streptococcus, grape ball
The gram positive bacterias such as bacterium, diphtheria have stronger inhibiting effect, when handling wound, can reduce exudation, mitigate pain, promote wound
Healing, prevents from infecting, has convergence, trophism to the surface of a wound.Honey in Example formulations is limited by the fragrant biotechnology of Shanghai letter
Company provides.
Propolis extract：Its chemical composition mainly has flavonoids, phenols, lactone, Coumarins, aldehyde, ketone, steroid chemical combination
Object, also contain vitamin B1, niacin, provitamin A and a variety of amino acid, sugar, 34 kinds of polysaccharide and indispensable element (oxygen, carbon, hydrogen,
Calcium, phosphorus, nitrogen, potassium, sulphur, sodium, chlorine, magnesium, iron, cobalt, copper, molybdenum, fluorine, aluminium etc.).
Preferably, propolis extract of the invention is prepared according to the method included the following steps：
1) propolis is dissolved into obtain medicinal extract with the ethyl acetate of 1-3 times of quality, stands 3-6 hours；Propolis used preferably uses
Fresh propolis is raw material
2) NaHCO that the mass concentration of 0.5~2 times of quality is 4~6% is added into the medicinal extract described in step 1)3It is water-soluble
Liquid extracts 2-5 hours at normal temperatures；
3) use hydrochloric acid acidification step 2) obtained by extracting solution, make its pH be 3-5；1~3 is added into the solution after acidified
The ether of times quality extracts 3-5 hours at normal temperatures, obtains ether extracted liquid；
4) ethyl acetate of 1~2 times of quality is added into ether extracted liquid obtained by step 3), and to extract 1-2 at normal temperatures small
When, obtain acetic acid ethyl acetate extract；
5) acetic acid ethyl acetate extract obtained by step 4) is concentrated under 80-90 DEG C of water bath condition with Rotary Evaporators, gained
Concentrate is through dry propolis extract.
There are no this foundation product containing 4 kinds of bee active components of the present invention occur currently on the market.The present invention carries
The foundation product of confession adds novel honeycomb compositions, even if can show good effect if under lower additive amount.It surveys
Test result shows that foundation product safety of the present invention added with this composition is high, and moistening effect is good, while having non-
Often comfortable skin sense, this product do not have a variety of skin-care effects singly, also have the function of hiding the flaw, skin care, collection nutrition is protected
It is wet, resist ultraviolet light, isolation dirty air and other effects, be a kind of novel product with good market application prospect.
The foundation cream prepared using technical solution of the present invention has patch skin and safety well.It is this added with specific
The foundation cream moistening effect of honeycomb compositions is more preferably, anti-inflammatory functional, antibacterial ability is also significantly improved.This kind of product is non-
Often it is suitable for children and sensibility skin, has widened the application range of product significantly.
Compared with present propolis product, present invention uses the honeycomb compositions of specific composition, foundation cream obtained is being protected
Wet, anti-inflammatory, strong skin, releiving etc. shows excellent performance.Compared with common foundation product, formula using the present invention
Patch skin, moisturizing degree, the antibacterial effect of the foundation cream of preparation, which are obtained for, to be obviously improved.The foundation product of the present invention has following
The characteristics of：
1) it is added to the foundation product of honeycomb compositions of the invention specific, containing largely to the ingredient of skin beneficiating,
It is functional more abundant such as proteins,vitamins,minerals and trace element.
2) compared with common moisturizer, honeycomb compositions have more obvious moisture-keeping efficacy, in low-down addition
Under amount, product shows excellent moistening effect.
3) it is milder, is highly safe, and is applicable to sensitive skin crowd and infant, has widened product
Sales Channel.
4) performance of foundation cream liquid product gets a promotion, and is added to the foundation product of honeycomb compositions of the present invention, it
Patch skin is obviously improved, and the skin sense of smearing is also significantly improved, and is moistened with rear skin emolliency.
5) ingredient of a variety of antibacterials contained in honeycomb compositions, these ingredients have the function of synergy, Ke Yi great
The big dosage for reducing preservative in formula, the safety of product are also further promoted.
Description of the drawings
Fig. 1 is performance of keeping humidity testing result.
Specific implementation mode
Technical scheme of the present invention is described further below in conjunction with the accompanying drawings：
Embodiment 1-2 is the foundation product embodiment of the present invention
Each raw material is weighed according to formula shown in the following table 1, wherein honeycomb compositions are weighed according to the corresponding proportioning in the following table 2.
Then foundation product is prepared in accordance with the following steps.
1) xanthans in B component is soaked with butanediol, is then added in water phase pot, opened stirring, sequentially add it
Its remaining B component is warming up to 80 DEG C, 10 minutes is kept the temperature, until being completely dissolved.
2) mixing speed of emulsification pot is maintained at 30 revs/min, and B component is passed through vacuum suck, low speed homogeneous 5 minutes.
3) raw material of component A is sequentially added in oil phase pot, is then heated to 80 DEG C, then inhale component A by vacuum
Enter to emulsify in pot, opens stirring, low speed homogeneous 10 minutes, and be cooled to 45 DEG C；
4) component C is added in emulsification pot, is stirred evenly, D components are then added, continue to stir；
5) it discharges when stirring is cooled to 38 DEG C.
6) it is qualified to examine, and discharging is filling.
Propolis extract used in embodiment 1-2 is all made of following steps preparation：
1) propolis is dissolved into obtain medicinal extract with the ethyl acetate of 2 times of quality, stands 4 hours；Propolis used uses fresh propolis
For raw material；
2) NaHCO that the mass concentration of 1 times of quality is 5% is added into the medicinal extract of step 1)3Aqueous solution carries at normal temperatures
It takes 4 hours；
3) use hydrochloric acid acidification step 2) obtained by extracting solution, make its pH be 4；2 times of matter are added into the solution after acidified
The ether of amount extracts 5 hours at normal temperatures, obtains ether extracted liquid；
4) ethyl acetate that 1 times of quality is added into ether extracted liquid obtained by step 3) extracts 2 hours at normal temperatures, obtains second
Acetoacetic ester extracting solution；
5) acetic acid ethyl acetate extract obtained by step 4) is concentrated under 90 DEG C of water bath conditions with Rotary Evaporators, gained concentration
Object is through dry propolis extract.
Reference examples
Each raw material that reference examples are weighed according to formula shown in the following table 1, referring next to the preparation method preparation pair of embodiment 1-2
Foundation product as usual.
Table 1
Table 2
Product testing
One, moisture-keeping efficacy is evaluated
Test method：Trier to the product for using embodiment 2 and reference examples has carried out human keratinous layer conductivity
Test and comparison, the moisturizing degree that conductivity increase represents skin increase.Before testing use respectively, using after 30 minutes, 1 hour
Afterwards, the cuticula conductivity after 2 hours and after 4 hours.
Test condition：Cuticula is detached and is placed it in a runner plate, which is adjusted 20 DEG C~25
DEG C, in 44%~60% relative humidity conditions.
Test result is referring to shown in Fig. 1 and the following table 3.By testing result it is found that embodiment 2 is compared with reference examples, moisturizing effect
Fruit, which has to compare, to be obviously improved, and using 2 hours, electric conductivity increases by 50~60%, and the moisturizing degree that represent product increases by 50~
60%.The test is also carried out to embodiment 1, result and embodiment 2 are essentially identical, repeat no more.
Table 3
Two, human skin patch
Evaluation method：
1.1 tested material：The product of Examples 1 to 2 and commercially available South Korea's famous brand name propolis BB are white (control group).
1.2 negative control：Blank control.
1.3 subject：Totally 25 people, male 12 people, 13 people of female, 18~30 years old age meet subject and volunteer inclusion criteria.
Spot method for testing：It selects spot to try device, in closed patch test method, tested material about 0.02ml~0.025ml is applied
In in spot examination device, external application special adhesive tape is pasted on subject's forearm song side, and tested material is removed after 24 hours, in removal tested material spot
30min after examination device observes dermoreaction after impression disappearance, presses《Cosmetics health specification》Dermoreaction point in (version in 2007)
Its result of grade standard recording.
1.4 evaluation of result：Reaction result is recorded by table 4 (skin adverse reaction grade scale).
Table 4
1.5 test result：It is shown in Table 5.
Table 5：Cosmetics human skin patch result
Remarks：Control group is commercially available South Korea's famous brand name propolis BB frosts.
The above results show that：In embodiment 1,2,25 all negative (grading systems of subjects skin：0 grade).
Foundation《Cosmetics health specification》(version in 2007) human skin class patch experiment criterion, sample are bad anti-without skin to human body
It answers, embodiment all has good safety.Control group has 21 order reactions, although having also passed through test, safety is owed
It is good.
Three, organoleptic analysis assesses
Appraisal procedure：
1) tested material：The cosmetics finished product of Examples 1 to 2 and reference examples.
2) subject：Totally 30 people, male 10 people, 20 people of female, 21~49 years old age meet subject and volunteer inclusion criteria.
3) appraisal procedure：0.3 gram of sample is applied to the back of the hand, mildly convolution smears 8 times, and then in a manner of marking (0
~10 points, score is higher, represents the texture of the product, spreadability, smooth degree, pastes skin, is better with rear comfort), this 5
The score value of index is added, and numerical value is higher, illustrates that properties of product are better.
Table 6
| Sample | Texture | Spreadability | Smooth degree | Paste skin | Comfort | Total score |
| Embodiment 1 | 8.0 | 8.7 | 9.2 | 9.0 | 9.3 | 44.2 |
| Embodiment 2 | 8.6 | 8.0 | 8.8 | 9.0 | 9.2 | 43.6 |
| Reference examples | 8.1 | 7.7 | 8.0 | 8.2 | 8.1 | 40.1 |
Assessment result：It applies comprehensive subject's scoring after to count, the results are shown in Table 6, the results show that embodiment 1-
2 foundation product, with rear skin smooth, soft, skin sense is comfortable, better.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (6)
1. a kind of containing there are many skin care item of honeycomb active constituent, which is characterized in that contain containing quality percentage in the skin care item
Amount is 1~3% honeycomb compositions, isohexadecane 3.0%~5.0%, isopropyl isostearate 1.0%~5.0%, different tristearin
Alcohol isostearate 1.0%~3.0%, methyl sesquistearate 1.0%~1.5%, caprylic/capric triglyceride
1.0%~6.0%, butanediol 2.0%~8.0%, PEG-20 methyls sesquistearate 0.8%~1.5%, xanthans
0.02%~0.3%, glucan 0.5%~3.0%, panthenol 0.5%~3.0%, bisabolol 0.1%~0.5%, the bee
Nest composition includes each component of following mass parts：10~40 parts of Mel extract, 10~40 parts of royal jelly, honey 10~40
Part, 10~40 parts of propolis extract；
The propolis extract is prepared according to the method included the following steps：
1) propolis is dissolved into obtain medicinal extract with the ethyl acetate of 1-3 times of quality, stands 3-6 hours；
2) NaHCO that the mass concentration of 0.5~2 times of quality is 4~6% is added into the medicinal extract described in step 1)3Aqueous solution is normal
Temperature lower extraction 2-5 hours；
3) use hydrochloric acid acidification step 2) obtained by extracting solution, make its pH be 3-5；1~3 times of matter is added into the solution after acidified
The ether of amount extracts 3-5 hours at normal temperatures, obtains ether extracted liquid；
4) ethyl acetate that 1~2 times of quality is added into ether extracted liquid obtained by step 3) extracts 1-2 hours at normal temperatures, obtains
Acetic acid ethyl acetate extract；
5) acetic acid ethyl acetate extract obtained by step 4) is concentrated under 80-90 DEG C of water bath condition with Rotary Evaporators, gained concentration
Object is through dry propolis extract.
2. skin care item according to claim 1, which is characterized in that also contain colorant 2%~8% in the skin care item.
3. skin care item according to claim 1, which is characterized in that in the skin care item also contain preservative 0.1%~
0.8%.
4. according to claims 1 to 3 any one of them skin care item, which is characterized in that the skin care item are foundation cream.
5. skin care item according to claim 4, which is characterized in that the skin care item by following mass percentage each group
It is grouped as：It is 1~3% honeycomb compositions, isohexadecane 3.0%~5.0%, isopropyl isostearate 1.0%~5.0%, different
Stearyl alcohol isostearate 1.0%~3.0%, methyl sesquistearate 1.0%~1.5%, caprylic/capric glycerine three
Ester 1.0%~6.0%, butanediol 2.0%~8.0%, PEG-20 methyls sesquistearate 0.8%~1.5%, xanthan
Glue 0.02%~0.3%, glucan 0.5%~3.0%, panthenol 0.5%~3.0%, bisabolol 0.1%~0.5%, coloring
Agent 2%~8%, preservative 0.1~0.8%, surplus water.
6. a kind of as claimed in claim 5 containing there are many preparation methods of the skin care item of honeycomb active constituent, which is characterized in that
Include the following steps：
1) each component is weighed according to formula, the formula is grouped as by each group of following mass percentage：1~3% honeycomb
Composition, isohexadecane 3.0%~5.0%, isopropyl isostearate 1.0%~5.0%, isooctadecanol isostearate
1.0%~3.0%, methyl sesquistearate 1.0%~1.5%, caprylic/capric triglyceride 1.0%~6.0%,
Butanediol 2.0%~8.0%, PEG-20 methyls sesquistearate 0.8%~1.5%, xanthans 0.02%~
0.3%, glucan 0.5%~3.0%, panthenol 0.5%~3.0%, bisabolol 0.1%~0.5%, colorant 2%~
8%, preservative 0.1~0.8%, surplus water；
Wherein, the honeycomb compositions include each component of following mass parts：10~40 parts of Mel extract, royal jelly 10~40
Part, 10~40 parts of honey, 10~40 parts of propolis extract；
2) xanthans is soaked with butanediol, is then added in water phase pot, PEG-20 methyl sesquialter stearic acid is added in stirring
Ester, water are warming up to 75~85 DEG C, and heat preservation is spare as B phases until being completely dissolved；
3) B phases obtained by step 2) are emulsified by vacuum suck in pot, homogeneous；
4) by colorant, isohexadecane, isopropyl isostearate, isooctadecanol isostearate, methyl sesquialter stearic acid
Ester, caprylic/capric triglyceride sequentially add in oil phase pot, are then heated to 75~85 DEG C, as A phases, then pass through A phases
Vacuum suck emulsifies in pot, and stirring, homogeneous are cooled to 40~50 DEG C；
5) glucan, panthenol are added in emulsification pot, stir evenly, remaining components are then added, continues to stir；
6) 38 DEG C are cooled to hereinafter, discharging.
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| CN110882207B (en) * | 2019-12-23 | 2022-05-20 | 广州曼姗生物科技有限公司 | Preparation process and method of essence for skin repair |
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| CN102935091A (en) * | 2012-11-19 | 2013-02-20 | 广西蜜博士蜂业有限责任公司 | Propolis flavonoid extracting method |
| CN103251531A (en) * | 2013-04-28 | 2013-08-21 | 福建省梦娇兰日用化学品有限公司 | Relief propolis cream |
| CN105380873A (en) * | 2015-11-17 | 2016-03-09 | 中国科学院西北高原生物研究所 | Moisturizing essence containing nitraria seed oil |
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2016
- 2016-04-12 CN CN201610231960.8A patent/CN105726448B/en active Active
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1485024A (en) * | 2002-09-28 | 2004-03-31 | 戚海波 | Bee honey and its use in beautifying cosmetics |
| CN101305977A (en) * | 2008-06-20 | 2008-11-19 | 范暄民 | Cosmetic product of honeybee products |
| CN102935091A (en) * | 2012-11-19 | 2013-02-20 | 广西蜜博士蜂业有限责任公司 | Propolis flavonoid extracting method |
| CN103251531A (en) * | 2013-04-28 | 2013-08-21 | 福建省梦娇兰日用化学品有限公司 | Relief propolis cream |
| CN105380873A (en) * | 2015-11-17 | 2016-03-09 | 中国科学院西北高原生物研究所 | Moisturizing essence containing nitraria seed oil |
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