CN106491440A - A kind of Flos Rosae Rugosae condensed fluid and the compositionss comprising the Flos Rosae Rugosae condensed fluid - Google Patents
A kind of Flos Rosae Rugosae condensed fluid and the compositionss comprising the Flos Rosae Rugosae condensed fluid Download PDFInfo
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract
The invention discloses a kind of Flos Rosae Rugosae condensed fluid and the compositionss comprising the Flos Rosae Rugosae condensed fluid, the Flos Rosae Rugosae condensed fluid is prepared by the following method：Water content is taken in 75 90% rosebuds or corolla, Hua Di is dispelled；2) by the Flos Rosae Rugosae after the base of a fruit of dispelling, it is 50 60% to dry to moisture content, collects condensed fluid；3) dried Flos Rosae Rugosae is continued microwave drying to water content≤10%, changes condensate collector, collect condensed fluid；4) by step 2) condensed fluid carry out freeze concentration, with step 3 after concentration) condensed fluid mix, obtain Flos Rosae Rugosae condensed fluid.The Flos Rosae Rugosae condensed fluid of the present invention is a kind of antibacterial of natural Chinese medicines, whitening, antioxidative cosmetic product, which has stronger inhibitory action to Candida albicans, propanoic acid Propiobacterium, tool core clostridium, escherichia coli, tyrosinase activity can be suppressed simultaneously, have antioxidant activity；Without antibiotic, hormone, skin mucosa is had no stimulation.
Description
Technical field
The present invention relates to cosmetic field, more particularly to a kind of Flos Rosae Rugosae condensed fluid and the group comprising the Flos Rosae Rugosae condensed fluid
Compound.
Background technology
Flos Rosae Rugosae (Rosa rugosa Thumb.), belongs to rosaceous plant, is the flower with very high edible and medical value
Grass, containing bioactive ingredients such as aromatic substance, polyphenol, flavone, exempts from certain antioxidation, antithrombotic, anticancer, antibacterial
Epidemic disease such as adjusts at the biological activity, and its sweet in the mouth and slight bitter are warm in nature, with Regulate the flow of vital energy Xie Yu, promoting blood circulation to remove blood stasis, menstruction regulating and pain relieving effect, be woman
The conventional material of section.However, the process of rose tea is prepared in heat drying, can produce substantial amounts of vapor, part volatility
Material can be lost in water vapour, cause the significant wastage of effective ingredient, Some Enterprises to evaporation after vapor condense
Process, acquisition part condensed fluid, but the not cognition to its science.
Flos Rosae Rugosae lower floor after Flos Rosae Rugosae quintessence oil is extracted can produce substantial amounts of rose wate solution, referred to as rose flower water, or
Cell reveals.Rose flower water has unique Flos Rosae Rugosae fragrance, containing multiple Polyphenols and volatility class active substance, and has certain
Antioxidation and whitening function, can use food, the exploitation of beverage, cosmetics and medicine.Fragrance component in rose flower water is main
For phenethanol, Radix Cinnamomi porrecti alcohol, eugenol, citronellol etc., these aromatic substances constitute cell and reveal special Flos Rosae Rugosae fragrance, so as to
Give cell dew as aromatic substance additive characteristic, in addition in its aqueous solution also have containing a small amount of kaempferol, rutin,
There is obvious tryrosinase to suppress for Quercetin, multiflorin A, multiflorin B, hyperin isoreactivity composition, these effective ingredient
Effect, particularly flavones ingredient can be with the activity of competitive inhibition tryrosinase.
Application No. 201510759448.6, the patent of entitled " a kind of Flos Rosae Rugosae fresh and alive water and preparation method and application "
The reduced steam way of distillation that application is adopted, the method need to apply vacuum equipment, are unfavorable for industrialized production, in addition through overdrying
The application of the Flos Rosae Rugosae after dry still will be compared with multiple operation.Application No. 201510396051.5, a kind of entitled " Flos Rosae Rugosae microwave thermal
Wind completes extracting method " patent application completed using microwave heating, flower received by hot air drying, and collects condensed fluid, to condensed fluid
Application not yet study, its drying process is complex.
At present, industrialized production Flos Rosae Rugosae condensed fluid and application reason are still in blank stage.The present invention is carried on this basis
Go out a kind of preparation method of Flos Rosae Rugosae condensed fluid and the cosmetic composition comprising the Flos Rosae Rugosae condensed fluid.
Content of the invention
The technical problem to be solved is to provide a kind of Flos Rosae Rugosae condensed fluid and comprising the Flos Rosae Rugosae condensed fluid
Compositionss, so that overcome the drawbacks described above of prior art.
The present invention is based on following principle：Rose tea can produce substantial amounts of vapor in dry run, can wherein contain
Some volatile material, after condensation, the condensed fluid of output there is no active reporter.Optimized production process of the present invention, condensed fluid point
Former and later two stages collect, and back segment volatilizees, and oil concentration is higher directly can be utilized, and leading portion condensed fluid can be according to the actual feelings of factory
Condition select concentration using or need as other purposes, further concentrating after condensation makes active substance assign to up to finite concentration to be also
One of present invention；Activity research finds that condensed fluid has good antibacterial, whitening, antioxidation.
The technical problem to be solved is achieved through the following technical solutions：
A kind of Flos Rosae Rugosae condensed fluid, is prepared by the following method：
1) water content is taken in 75-90% rosebuds or corolla, dispel Hua Di；
2) by step 1) Flos Rosae Rugosae after the base of a fruit of dispelling, it is 50-60% to dry to moisture content, collects condensed fluid；
3) by step 2) dried Flos Rosae Rugosae continues microwave drying to water content≤10%, changes condensate collector,
Collect condensed fluid；
4) by step 2) condensed fluid carry out freeze concentration, with step 3 after concentration) condensed fluid mix, obtain Flos Rosae Rugosae cold
Lime set.
A kind of Flos Rosae Rugosae condensed fluid, is prepared by the following method：
1) water content is taken in 75-90% rosebuds or corolla, dispel Hua Di；
3) by step 1) Flos Rosae Rugosae after the base of a fruit of dispelling, it is 50-60% to dry to moisture content, collects condensed fluid；
3) by step 2) dried Flos Rosae Rugosae continues microwave drying to water content≤10%, changes condensate collector,
Collect condensed fluid；
4) condensed fluid that 3) removal step collects, obtains Flos Rosae Rugosae condensed fluid.
Preferably, in above-mentioned technical proposal, the drying is microwave drying or hot air drying, and the dry time is 5-
15min.
Preferably, in above-mentioned technical proposal, the rosebud or corolla are selected from polyphyll Flos Rosae Rugosae, golden-rimmed Flos Rosae Rugosae or misery
One or more of Flos Rosae Rugosae.
A kind of compositionss comprising Flos Rosae Rugosae condensed fluid, the compositionss include following raw material component：Flos Rosae Rugosae
Condensed fluid 0.5-100 and pharmaceutical adjunct 1-99.5, it is preferable that
Preferably, in above-mentioned technical proposal, the compositionss include following raw material component：Flos Rosae Rugosae condensed fluid 1-
20 and pharmaceutical adjunct 80-99, the pharmaceutical adjunct is conventional formulation adjuvant.
A kind of application of compositionss of Flos Rosae Rugosae condensed fluid in cosmetics.
Preferably, in above-mentioned technical proposal, the dosage form of the cosmetics is unguentum, spray or paste.
Preferably, in above-mentioned technical proposal, when the dosage form of the cosmetics is unguentum, the pharmaceutical adjunct includes following
Raw material component：The viscous dimethicone 1.0-8.0 of polyoxyethylene ether cetyl phosphate three ester 2.0-10,5-, Jojoba oil
5.0-20, hexadecanol 3.0-9, squalane 8.0-30, acrylamide dimethyltaurine ammonium copolymer 1 .1-4, ethyl hydroxybenzoate
0.2-0.5, Propylene Glycol 2.0-6.0, purified water supply 100 parts；When the cosmetics dosage form be spray, the pharmaceutical adjunct
Including following raw material component：Sodium chloride 0.2-0.5, the sodium phosphate that ethylenediaminetetraacetic acid 0.030-0.060, pH are 6.5
Buffer 0.3-0.6, Spheron MD 30/70 0.30-0.60, water 92-98；When the dosage form of the cosmetics is paste, the adjuvant
Including following raw material component：Polyethylene Glycol 14.45-15, glycerol 14.995-15, calcium powder 60-70.
Preferably, in above-mentioned technical proposal, in the cosmetics, Flos Rosae Rugosae condensation liquid hold-up is cosmetic product gross weight
1%-99%.
Preferably, in above-mentioned technical proposal, in the Flos Rosae Rugosae condensed fluid, the species of effective ingredient is Radix Cinnamomi porrecti alcohol, benzene second
Alcohol, citronellol, bisabolol, kaempferol -3-O- rutin glycosides；In the Flos Rosae Rugosae condensed fluid, active substance total content is produced for making up
One of percentage of product gross weight is to ten a ten thousandths.
Above-mentioned technical proposal of the present invention, has the advantages that：
The present invention breaks through the defect of prior art, and which is a kind of pure using cosmetic composition prepared by Flos Rosae Rugosae condensed fluid
The antibacterial of natural Chinese medicine, whitening, antioxidative cosmetic product, the principle active component of the cosmetic product is Flos Rosae Rugosae condensed fluid,
Which has good antibacterial, sterilization, whitening, antioxidation, to Candida albicans, propanoic acid Propiobacterium, tool core clostridium, large intestine
Bacillus.There is stronger inhibitory action, while tyrosinase activity can be suppressed, have antioxidant activity；Without antibiotic, swash
Element, has no stimulation to skin mucosa.
Description of the drawings
Fig. 1 is Flos Rosae Rugosae condensed fluid volatile ingredient total ion current figure.
Wherein：1- Radix Cinnamomi porrecti alcohol, 2 phenylethyl alcohol, 3- citronellols, 5- citronellol ethyl esters, 6 bisabolols.
Fig. 2 is Flos Rosae Rugosae condensed fluid water-soluble substanceses figure.
Wherein：1- hyperins, 2- kaempferol -3-O- rutin glycosides, 3- rutins.
Specific embodiment
Below the specific embodiment of the present invention is described in detail, in order to further understand the present invention.
In following examples, all experimental techniques for using if no special instructions, are conventional method.
Material used, reagent etc. in following examples, if no special instructions, can pass through commercial sources or existing method
Prepare.
The preparation of 1 Flos Rosae Rugosae condensed fluid of embodiment
A kind of Flos Rosae Rugosae condensed fluid, is prepared by the following method：
1) water content is taken in 75-85% rose Flos Rosae Rugosae corolla 50kg, dispel Hua Di.
2) dispel the Flos Rosae Rugosae corolla after the base of a fruit, insert microwave dryer and dry 5-15min, it is 50- to dry to moisture content
Between 60%, condensed fluid 410mL is collected.
3) continue microwave drying 15-20min and condensate collector is changed to water content below 10%, collect condensed fluid
460mL.
4) by step 2) condensed fluid carry out freeze concentration to 200mL, with step 3 after concentrating one times) condensed fluid mix
Use, obtain Flos Rosae Rugosae condensed fluid.
The preparation of 2 Flos Rosae Rugosae condensed fluid of embodiment
A kind of Flos Rosae Rugosae condensed fluid, is prepared by the following method：
1) water content is taken in 75-80% rose rosebud 50kg, dispel Hua Di；
2) dispel the Flos Rosae Rugosae corolla after the base of a fruit, insert microwave dryer and dry 5-15min, it is 50- to dry to moisture content
Between 60%, condensed fluid 320mL is collected；
3) continue microwave drying 15-20min and condensate collector is changed to water content below 10%, collect condensed fluid
430mL.
4) condensed fluid that 3) removal step collects, obtains Flos Rosae Rugosae condensed fluid.
The preparation of 3 Flos Rosae Rugosae condensed fluid of embodiment
A kind of Flos Rosae Rugosae condensed fluid, is prepared by the following method：
1) water content is taken in 75-85% rose Flos Rosae Rugosae corolla 50kg, dispel Hua Di.
2) dispel the Flos Rosae Rugosae corolla after the base of a fruit, be delivered to microwave dryer and dry 25-45min, dry to moisture content and be
Less than 10%, collect condensed fluid 860mL.
3) condensed fluid is carried out freeze concentration to 420mL, obtains the Flos Rosae Rugosae condensed fluid.
4 analysis of effective component of embodiment
Analysis of effective component is carried out to the Flos Rosae Rugosae condensed fluid that 1 method of embodiment is prepared,
Chromatographic condition：Rtx-5MS quartz elasticities capillary capillary column (30m × 0.25mm × 0.25 μm)；Carrier gas is He
(99.999%), flow control mode；Linear velocity flow 1.0ml min-1, injector temperature：250℃；Chromatographic column is initially warm
80 DEG C, 140 DEG C are warmed up to 3 DEG C of min-1, rise to 200 DEG C with 2 DEG C of min-1, rise to 280 DEG C with 10 DEG C of min-1, most
10mins is kept afterwards；3.0mins, split ratio 1 sample introduction are not shunted.
Mass Spectrometry Conditions：Ionization mode；EI sources, energy 70eV；250 DEG C of ion source temperature, 280 DEG C of interface temperature, solvent prolongs
The slow time：3.0mins, detector gain mode：Relative, detector gain：0.82kv+0.00kv.Mass range 35-
500amu；Whole scanning, time interval：0.3s, scanning speed：1666.
As a result as shown in table 1 below：
1 Flos Rosae Rugosae condensed fluid volatile component content table (10 of table-6mg/mL)
| Compound | RT | Structural formula | Molecular weight | Condensed fluid |
| Radix Cinnamomi porrecti alcohol | 12.163 | C10H180 | 154.25 | 1.21±2.18 |
| Phenethanol | 12.921 | C8H10O | 122.16 | 80.26±2.24 |
| Citronellol | 20.393 | C10H20O | 156.27 | 7.83±0.77 |
| Phenethanol ethyl ester | 21.923 | C10H1202 | 164.2 | 11.20±0.89 |
| Bisabolol | 49.909 | C15H26O | 222.36 | 0.08±0.01 |
| Total amount | 91.21±3.89 |
5 Flos Rosae Rugosae condensate mixture bacteriostatic experiment of embodiment
(1) the selection propionibacterium acness (ATCC 6919) of experimental strain, Candida albicans (ATCC 10231) have core
Fusobacterium (ATCC 25586), escherichia coli (ATCC 25922).(being purchased from Guangdong Province's Organism Depositary above)
(2) operating procedure：
A. above-mentioned four kinds of pathogenic bacterium are taken, is inoculated on sabouraud culture medium, in corresponding incubator, 38 DEG C, cultivated 72 hours.
B. the bacterium solution after re-activation is taken, and 10 is diluted to Sharpe fluid medium8CFU/mL.
C. by dilution after bacterium solution be added in 96 orifice plates, per hole add 100 microlitres, hereafter press doubling dilution add
100 microlitres of Flos Rosae Rugosae condensed fluid dissolved with dimethyl sulfoxide (DMSO), to add the erythromycin of equivalent as positive control, are put into
Incubator, cultivates 24-72 hours under the conditions of 37 DEG C,；
D. its minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MFC) is determined according to long bacterium situation.
(3) experimental result is as shown in table 2：
The antibacterial activity (μ g/mL) of 2 Flos Rosae Rugosae condensed fluid of table
Experimental result shows：Ordinary cells dew does not have the effect for suppressing antibacterial；After fractional condensation and concentration
There is stronger inhibitory action to skin pathomycete.
The antioxidation of 6 Flos Rosae Rugosae condensed fluid of embodiment and whitening experiment
Antioxidation and whitening experiment is carried out to the Flos Rosae Rugosae condensed fluid that embodiment 1 is obtained.As a result as shown in table 3：
3 Flos Rosae Rugosae condensed fluid antioxidation of table and the IC of tyrosinase inhibitory activity50Value (mg/ml)
| DPPH | Tryrosinase suppresses | ABTS | |
| Flos Rosae Rugosae condensed fluid | 1.12±0.04 | 0.57±0.02 | 1.43±0.05 |
| Ordinary cells are revealed | >4 | 3.21±0.04 | 3.84±0.06 |
| Positive control | <0.001 | <0.001 | <0.001 |
Cosmetics (unguentum) of the embodiment 7 containing Flos Rosae Rugosae condensed fluid
A kind of antibacterial containing Flos Rosae Rugosae condensed fluid, whitening, antioxidative externally used paste
1) raw material (kg) is taken：Flos Rosae Rugosae condensed fluid 60, substrate adjuvant 40.
2) substrate composition method (part)：Three ester 2.0,5- of polyoxyethylene ether cetyl phosphate glue dimethicone 1.0, flash
Bar oil 5.0, hexadecanol 3.0, squalane 8.0, acrylamide dimethyltaurine ammonium copolymer 1 .1, ethyl hydroxybenzoate 0.2, third
Glycol 2.0, purified water supplies 100.
3) preparation method：Active component Flos Rosae Rugosae condensed fluid is taken, substrate stirs mixing and emulsifying at 80 ± 5 DEG C, adds successively
Qs glycerin diluent, the stirring mixing of KF88 aqueous solution make emulsifying, let cool, get product after ageing.
With Flos Rosae Rugosae condensed fluid as active substance, Flos Rosae Rugosae condensed fluid has whitening, slow down aging to the external product, resists
Inflammation, analgesic efficacy, external according to known to experiment can suppress the growth of pathogenic bacterium again, be a kind of safe, the natural plants of high-quality
Medicine external product.
Cosmetics (unguentum) of the embodiment 8 containing Flos Rosae Rugosae condensed fluid
Its preparation method is similar to Example 7, is only amended as follows substrate composition：Three ester of polyoxyethylene ether cetyl phosphate
10th, 5- viscous dimethicone 8.0, Jojoba oil 20, hexadecanol 9, squalane 30, acrylamide dimethyltaurine ammonium copolymer
4th, ethyl hydroxybenzoate 0.5, Propylene Glycol 6.0, purified water supplies 100.
Cosmetics (unguentum) of the embodiment 9 containing Flos Rosae Rugosae condensed fluid
Its preparation method is similar to Example 7, is only amended as follows substrate composition：Three ester of polyoxyethylene ether cetyl phosphate
5.0th, the viscous dimethicones 6.0 of 5-, Jojoba oil 12, hexadecanol 6.0, squalane 20, acrylamide dimethyltaurine ammonium are common
Polymers 2.5, ethyl hydroxybenzoate 0.35, Propylene Glycol 4.0, purified water supplies 100.
Cosmetics (spray) of the embodiment 10 containing Flos Rosae Rugosae condensed fluid
A kind of antifungal external nursing spray containing Flos Rosae Rugosae condensed fluid
1) raw material (kg) is taken：Flos Rosae Rugosae condensed fluid 50, sodium chloride 0.5, EDTA (ethylenediaminetetraacetic acid) 0.060, pH are 6.5
Sodium phosphate buffer 0.6, Spheron MD 30/70 0.60, water 98.
2) preparation method：EDTA and Spheron MD 30/70 are added to the water according to proportioning, 60 DEG C are heated to, add Radix Notoginseng to turn
Change saponin and sodium chloride, to be cooled to adding sodium phosphate buffer (pH 6.5), addition water to supply 100kg during room temperature, mixing is
Even, through canned, high temperature sterilize, obtain skin-protection spray.
Cosmetics (spray) of the embodiment 11 containing Flos Rosae Rugosae condensed fluid
Its preparation method is similar to Example 10, is only amended as follows proportioning raw materials：Flos Rosae Rugosae condensed fluid 50, sodium chloride
0.2nd, EDTA (ethylenediaminetetraacetic acid) 0.030, pH be 6.5 sodium phosphate buffer 0.3, Spheron MD 30/70 0.3, water 92.
Cosmetics (spray) of the embodiment 12 containing Flos Rosae Rugosae condensed fluid
Its preparation method is similar to Example 10, is only amended as follows proportioning raw materials：Flos Rosae Rugosae condensed fluid 50, sodium chloride
0.35th, EDTA (ethylenediaminetetraacetic acid) 0.045, pH be 6.5 sodium phosphate buffer 0.45, Spheron MD 30/70 0.5, water 95.
Cosmetics (paste) of the embodiment 13 containing Flos Rosae Rugosae condensed fluid
A kind of antibacterial containing Flos Rosae Rugosae condensed fluid, whitening, antioxidation paste
1) following raw material (kg) is taken：Flos Rosae Rugosae condensed fluid 8, Polyethylene Glycol 14.45, glycerol 14.995, calcium powder 60.
2) preparation method：Respectively Polyethylene Glycol, glycerol, Flos Rosae Rugosae condensed fluid are mixed by weight proportion, 40 DEG C are heated to,
Stirring mixing, then calcium powder is added thereto stir after obtain final product paste.
Cosmetics (paste) of the embodiment 14 containing Flos Rosae Rugosae condensed fluid
Its preparation method is similar to embodiment 13, is only amended as follows proportioning raw materials：Flos Rosae Rugosae condensed fluid 4, Polyethylene Glycol
15th, glycerol 15, calcium powder 66.
Cosmetics (paste) of the embodiment 15 containing Flos Rosae Rugosae condensed fluid
Its preparation method is similar to embodiment 13, is only amended as follows proportioning raw materials：Flos Rosae Rugosae condensed fluid 4, Polyethylene Glycol
12nd, glycerol 12, calcium powder 70.
Toothpaste of the embodiment 16 containing Flos Rosae Rugosae condensed fluid
Specific embodiments of the present invention, the formula of care toothpaste and composition (except specified otherwise is, institute in remaining present invention
The quality and ratio that states is the content and ratio of quality).
1) formula：Sorbitol (70%) 30～45%；Silicon dioxide 30～45%；Sodium carboxymethyl cellulose 0.45～
0.55%；Silicon dioxide 5～15%；Sodium laurylsulfate 0.9%～1.9%；Flos Rosae Rugosae condensed fluid 4.5～5.5%；Pure water
1.5-2.5%.
2) manufacture method：By Sorbitol (70%), glycerol, silicon dioxide, sodium carboxymethyl cellulose, lauryl alcohol, Flos Rosae Rugosae
Sodium carboxymethyl cellulose and glycerol are now sufficiently mixed and make glycerol colloid, is subsequently agitated for homogenizing and mixed by condensed fluid, pure water
Compound A, by Flos Rosae Rugosae condensed fluid, Sorbitol, liquid sodium laurylsulfate (K12) uniformly mix equal compound A of addition with pure water
In, mixture B is stirring uniformly to obtain, silicon dioxide is added in equal compound B, be evenly stirred until transparent, obtain equal compound C, plus
Enter essence, stir, froth in vacuum is canned.
The present invention breaks through the defect of prior art, and which is a kind of pure using cosmetic composition prepared by Flos Rosae Rugosae condensed fluid
The antibacterial of natural Chinese medicine, whitening, antioxidative cosmetic product, the principle active component of the cosmetic product is Flos Rosae Rugosae condensed fluid,
Which has good antibacterial, sterilization, whitening, antioxidation, to Candida albicans, propanoic acid Propiobacterium, tool core clostridium, large intestine
Bacillus.There is stronger inhibitory action, while tyrosinase activity can be suppressed, have antioxidant activity；Without antibiotic, swash
Element, has no stimulation to skin mucosa.
Although the present invention is disclosed as above with embodiment, so which is not intended to limit the present invention, any people in the art
Member, without departing from the spirit and scope of the present invention, can make a variety of selections and modification, therefore protection model of the invention
Enclose and limited by claims and its equivalents.
Claims (10)
1. a kind of Flos Rosae Rugosae condensed fluid, it is characterised in that the Flos Rosae Rugosae condensed fluid is prepared by the following method：
1) water content is taken in 75-90% rosebuds or corolla, dispel Hua Di；
2) by step 1) Flos Rosae Rugosae after the base of a fruit of dispelling, it is 50-60% to dry to moisture content, collects condensed fluid；
3) by step 2) dried Flos Rosae Rugosae continues microwave drying to water content≤10%, and condensate collector is changed, is collected
Condensed fluid；
4) by step 2) condensed fluid carry out freeze concentration, with step 3 after concentration) condensed fluid mix, obtain Flos Rosae Rugosae condensed fluid.
2. a kind of Flos Rosae Rugosae condensed fluid, it is characterised in that the Flos Rosae Rugosae condensed fluid is prepared by the following method：
1) water content is taken in 75-90% rosebuds or corolla, dispel Hua Di；
2) by step 1) Flos Rosae Rugosae after the base of a fruit of dispelling, it is 50-60% to dry to moisture content, collects condensed fluid；
3) by step 2) dried Flos Rosae Rugosae continues microwave drying to water content≤10%, and condensate collector is changed, is collected
Condensed fluid；
4) condensed fluid that 3) removal step collects, obtains Flos Rosae Rugosae condensed fluid.
3. Flos Rosae Rugosae condensed fluid according to claim 1 and 2, it is characterised in that the drying is microwave drying or hot blast
Dry, the dry time is 5-15min.
4. Flos Rosae Rugosae condensed fluid according to claim 1 and 2, it is characterised in that the rosebud or corolla are selected from
One or more of polyphyll Flos Rosae Rugosae, golden-rimmed Flos Rosae Rugosae or Rose grievances.
5. a kind of compositionss comprising the arbitrary described Flos Rosae Rugosae condensed fluid of claim 1-4, it is characterised in that the compositionss
Including following raw material component：Flos Rosae Rugosae condensed fluid 0.5-100 and pharmaceutical adjunct 1-99.5, preferably.
6. compositionss of Flos Rosae Rugosae condensed fluid according to claim 5, it is characterised in that the compositionss include following heavy
Amount part raw material components：Flos Rosae Rugosae condensed fluid 1-20 and pharmaceutical adjunct 80-99, the pharmaceutical adjunct are conventional formulation adjuvant.
7. the application according to the compositionss of the arbitrary described Flos Rosae Rugosae condensed fluid of claim 5-6 in cosmetics, its feature exist
In the dosage form of the cosmetics is unguentum, spray or paste.
8. application of the compositionss of Flos Rosae Rugosae condensed fluid according to claim 7 in cosmetics, it is characterised in that
When the dosage form of the cosmetics is unguentum, the pharmaceutical adjunct includes following raw material component：Polyoxyethylene ether
The viscous dimethicone 1.0-8.0 of cetyl phosphate three ester 2.0-10,5-, Jojoba oil 5.0-20, hexadecanol 3.0-9, squalane
8.0-30, acrylamide dimethyltaurine ammonium copolymer 1 .1-4, ethyl hydroxybenzoate 0.2-0.5, Propylene Glycol 2.0-6.0, purification
Water supplies 100 parts；
When the dosage form of the cosmetics is spray, the pharmaceutical adjunct includes following raw material component：Sodium chloride 0.2-
0.5th, ethylenediaminetetraacetic acid 0.030-0.060, pH be 6.5 sodium phosphate buffer 0.3-0.6, Spheron MD 30/70 0.30-0.60,
Water 92-98；
When the dosage form of the cosmetics is paste, the adjuvant includes following raw material component：Polyethylene Glycol 14.45-
15th, glycerol 14.995-15, calcium powder 60-70.
9. application of the compositionss of Flos Rosae Rugosae condensed fluid according to claim 8 in cosmetics, it is characterised in that described
1%-99% of the Flos Rosae Rugosae condensation liquid hold-up for cosmetic product gross weight in cosmetics.
10. application of the compositionss of Flos Rosae Rugosae condensed fluid according to claim 9 in cosmetics, it is characterised in that institute
The species for stating effective ingredient in Flos Rosae Rugosae condensed fluid is Radix Cinnamomi porrecti alcohol, phenethanol, citronellol, bisabolol, kaempferol -3-O- rutins
Glycosides；In the Flos Rosae Rugosae condensed fluid, active substance total content is one of percentage of cosmetic product gross weight to ten a ten thousandths.
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| CN114854495A (en) * | 2022-06-16 | 2022-08-05 | 银谷芳香科技有限公司 | Process method for extracting damascus rose essential oil by sectional distillation |
| CN114854495B (en) * | 2022-06-16 | 2023-11-03 | 银谷芳香科技有限公司 | Technological method for extracting Damascus rose essential oil through sectional distillation |
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Application publication date: 20170315 |