CN106489951A - A kind of Pesticidal combination containing ring bromine insect amide - Google Patents
A kind of Pesticidal combination containing ring bromine insect amide Download PDFInfo
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- CN106489951A CN106489951A CN201610888199.5A CN201610888199A CN106489951A CN 106489951 A CN106489951 A CN 106489951A CN 201610888199 A CN201610888199 A CN 201610888199A CN 106489951 A CN106489951 A CN 106489951A
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- insect amide
- ring bromine
- bromine insect
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
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- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of Pesticidal combination containing ring bromine insect amide, effective active composition is made up of the first active component ring bromine insect amide and the second active component Tolfenpyrad or the one kind in flonicamid, and the weight ratio of the first active component and the second active component is 1:60～60:1, content sum is the 1%～80% of the composition total weight.Missible oil that this composition can be configured to agriculturally to allow, suspending agent, wettable powder, water dispersible granules, aqueous emulsion, microemulsion, microcapsule formulations, granule, aqua formulation.Instant component is reasonable, good to the Semipteras such as tea lesser leafhopper, thrips, diamondback moth, plant hopper, aphid, Thysanoptera, Lepidoptera, homoptera pest effect, and its insecticidal effect is not the simple superposition of each component activity, compared with existing unitary agent, in addition to significant insecticidal effect, and having significant synergistic effect, dosage is reduced, good to crop safety.
Description
Technical field
The present invention relates to a kind of Pesticidal combination containing ring bromine insect amide and application thereof, composition is by the first active component
Ring bromine insect amide, the second active component Tolfenpyrad or flonicamid and auxiliary agent composition, belong to technical field of compounded pesticide.
Background technology
Ring bromine insect amide, English name is cyclaniliprole, and chemical name is：The bromo- N- of 3- [the chloro- 6- of the bromo- 4- of 2-
[[(1- cyclopropylethyls) amine] carbonyl] phenyl] -1- (3- Chloro-2-Pyridyles) -1H- pyrazoles -5- formamides, test code number is IKI-
3106, CAS：1031756-98-5.The bisamide insecticides that Japanese Ishihara Sangyo Kaisha, Ltd. develops.There is systemic activity,
Broad-spectrum insecticidal activity, has good prevention effect to insects such as diamondback moth, prodenia litura, aleyrodid, aphid, thrips, liriomyza bryoniaes.
Tolfenpyrad, English name is tolfenpyrad, and chemical name is：The chloro- 3- ethyls -1- methyl-N- [4- of 4-
(p- tolyl epoxide) phenyl] pyrazoles -5- acid amides.The novel pyrazole heterocyclic desinsection of Shi Yuan Mitsubishis chemical company exploitation
Acaricide, its main mechanism be prevent insect oxidative phosphorylation, also have ovicidal, suppression food, oviposition deterrence and
Bactericidal action.
Flonicamid, English name is flonicamid, and chemical name is：N- cyanogen methyl -4- (trifluoromethyl) nicotinoyl
Amine.Not only have and tag and stomach poison function, also there is good never poison and quick antifeedant effect.The sucking mouth parts such as aphid
After water of the pests suction with flonicamid, can be prevented to inhale juice by rapid, not drain completely within an hour
Thing occurs, finally dead because hungry.
Applicant, will be multiple with Tolfenpyrad or flonicamid for ring bromine insect amides different for the mechanism of action through test discovery
Match somebody with somebody, with advantages below and beneficial effect：1st, compound scheme is used, to tea lesser leafhopper, thrips, diamondback moth, plant hopper, aphid etc.
There is notable synergistic to act on for Semiptera, Thysanoptera, Lepidoptera, homoptera pest, significantly improve prevention effect；2nd, medication is reduced
Amount and times for spraying, reduce cost accounting；3rd, overcome single for a long time using the shortcoming for easily producing resistance, the use of prolongation medicament
Life-span.
Content of the invention
It is an object of the invention to provide a kind of component is reasonable, synergistic effect significantly, good disinsection effect, drug cost low,
Agricultural insecticidal composite to crop safety.
Another object of the present invention is to providing the Pesticidal combination formulation containing ring bromine insect amide.
It is still another object of the present invention to provide above-mentioned composition preventing and treating tea lesser leafhopper, thrips, diamondback moth, plant hopper,
Application on the Semipteras such as aphid, Thysanoptera, Lepidoptera, homoptera pest.
For achieving the above object, such solution the technical scheme is that：
A kind of Pesticidal combination containing ring bromine insect amide and Tolfenpyrad or flonicamid and application thereof, it is characterised in that
（1）First active component：Ring bromine insect amide；
（2）Second active component：One kind in Tolfenpyrad or flonicamid；
The weight ratio of the first active component and the second active component is 1:60～60:1, content sum is the composition total weight
1%～80%, preferably 5%～60%.
A kind of Pesticidal combination containing ring bromine insect amide of the present invention is according to the side well known to those skilled in the art of the present technique
The preparation formulation that method can be prepared is missible oil, suspending agent, wettable powder, water dispersible granules, aqueous emulsion, microemulsion, microcapsules
Agent, granule, aqua.
To missible oil, spendable auxiliary agent has：Emulsifying agent is selected from calcium dodecyl benzene sulfonate（Agriculture breast 500#）, Nongru-700 #,
Agriculture breast 2201, this disk -60#, emulsifying agent T-60（Common name：Anhydrous sorbitol single-hard ester acid ester APEO）、TX-10（Logical
With name：Octyl phenol polyoxyethylene（10）Ether）, agriculture breast 1601#, agriculture breast 600#, one or more in agriculture breast 400# etc.；Solvent is selected
From dimethylbenzene, solvent naphtha（S-150、S-180、S-200）, toluene, biodiesel, the one kind or many in methylated vegetable oil etc.
Kind；One or more in ethyl acetate, methyl alcohol, dimethylformamide, cyclohexanone, acetone, MEK etc. of cosolvent；Surely
Determine one or more in triphenyl phosphite, epoxychloropropane, aceticanhydride etc. of agent.
To suspending agent, spendable auxiliary agent has：Dispersant such as polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate（Expand
Powder NNO）、TERSPERSE 2020（Huntsman Corporation of the U.S. produces, alkyl naphthalene sulfonic acid salt）In one or more；Emulsifying agent
Such as Nongru-700 #（Common name：Alkyl phenol formaldehyde resin polyoxyethylene ether）, agriculture breast 2201, this disk -60#（Common name：Sorbitan
Alcohol stearate）, Tween-60 #（Common name：Polyoxyethylene sorbitan stearate）, agriculture breast 1601#（Common name：Triphen
Ethyl -phenol polyoxyethylene polyoxypropylene block polymer）、TERSPERSE 4894（Huntsman Corporation of the U.S. produces）In
One or more；Wetting agent such as alkylphenol-polyethenoxy base ether formaldehyde condensation products sulfate, alkylphenol-polyethenoxy base ether phosphoric acid
Ester, phenethyl phenol polyoxyethylene groups ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, TERSPERSE 2500
（Huntsman Corporation of the U.S. produces）One or more in；Thickener such as xanthans, polyvinyl alcohol, bentonite, aluminium-magnesium silicate
One or more in；One or more in preservative such as formaldehyde, benzoic acid, Sodium Benzoate etc.；Stabilizer such as epoxy is big
One or more in soya-bean oil, epoxychloropropane, triphenyl phosphate etc.；Defoamer such as silicone defoamer；Antifreezing agent such as second
One or more in glycol, propane diols, glycerine, urea, inorganic salts such as sodium chloride etc.；Water is deionized water.
To wettable powder, spendable auxiliary agent has：Dispersant such as polycarboxylate, lignosulfonates, polyoxyethylene gather
Oxypropylene group ether block copolymers, alkyl naphthalene formaldehyde condensate sulfonates, alkylphenol-polyethenoxy base ether phosphate, poly alkyl alcohol
One or more in oxygen ethene ether phosphate, alkylphenol-polyethenoxy base ether sulfonate etc.；Wetting agent such as alkyl sulfate, alkane
One or more in base sulfonate, alkylnaphthalene sulfonate etc.；Filler such as ammonium sulfate, urea, sucrose, glucose, diatomite, height
One or more in ridge soil, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay etc..
To water dispersible granules, spendable auxiliary agent has：Dispersant such as polycarboxylate（TERSPERSE 2700、T36、GY-
D06 etc.）, lignosulfonates, one or more in alkylnaphthalene sulfonate etc.；Wetting agent such as alkyl sulfate, alkyl sulfonic acid
One or more in salt, naphthalene sulfonate etc.；Disintegrant such as ammonium sulfate, sodium sulphate, polyvinylpyrrolidone, starch and its derivative
One or more in thing, bentonite etc.；Binding agent such as starch, glucose, polyvinyl alcohol, polyethylene glycol, carboxymethylcellulose calcium
One or more in sodium, sucrose etc.；Filler such as diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay
One or more in.
To aqueous emulsion, spendable auxiliary agent has：Emulsifying agent such as Nonyl pheno（EO=10）Ether phosphate, triphen second
Base phenol polyoxyethylene phosphonate, Nongru-700 #（Common name：Alkyl phenol formaldehyde resin polyoxyethylene ether）, agriculture breast 2201#, this
Disk -60#（Common name：Span60）, Tween-60 #（Common name：Polyoxyethylene sorbitan stearic acid
Ester）、TX-10（Common name：Octyl phenol polyoxyethylene（10）Ether）, agriculture breast 1601（Common name：Triphenoethyl benzene phenol polyoxypropylene gathers
Oxygen ethylene block polymer）, agriculture breast 600#, one or more in agriculture breast 400# etc.；Solvent for example dimethylbenzene, toluene, cyclohexanone,
Solvent naphtha（The trade mark：S-150、S-180、S-200）One or more in；Stabilizer such as triphenyl phosphite, epoxy chloropropionate
One or more in alkane, epoxidized soybean oil etc.；Antifreezing agent such as ethylene glycol, propane diols, glycerine, urea, inorganic salts such as chlorination
One or more in sodium etc.；One or more in thickener such as xanthans, polyvinyl alcohol, bentonite, aluminium-magnesium silicate etc.；Anti-
One or more in rotten agent such as formaldehyde, benzoic acid, Sodium Benzoate etc., water is deionized water.
To microemulsion, spendable auxiliary agent has：Emulsifying agent is selected from calcium dodecyl benzene sulfonate（Agriculture breast 500#）, agriculture breast
700#, agriculture breast 2201, this disk-60#, polysorbate60-#, TX-10, agriculture breast 1601（Common name：Phenethyl phenol polyoxyethylene polyoxy
Propylene ether）, agriculture breast 600#, one or more in agriculture breast 400# etc.；Assistant for emulsifying agent is selected from methyl alcohol, isopropanol, n-butanol, second
Alcohol；Solvent is selected from cyclohexanone, 1-METHYLPYRROLIDONE, dimethylbenzene, toluene, solvent naphtha（The trade mark：S-150、S-180、S-200）Deng
In one or more；One or more in triphenyl phosphite, epoxychloropropane etc. of stabilizer；Water is deionization
Water.
To microcapsule formulations, spendable auxiliary agent has：Emulsifying dispersant such as Nonyl pheno（EO=10）Ether phosphate,
Triphenoethyl benzene phenol polyethenoxy ether phosphate, Nongru-700 #（Common name：Alkyl phenol formaldehyde resin polyoxyethylene ether）, agriculture breast
2201#, this disk -60#（Common name：Span60）, Tween-60 #（Common name：Polyoxyethylene sorbitan
Stearate）、TX-10（Common name：Octyl phenol polyoxyethylene（10）Ether）, agriculture breast 1601（Common name：Triphenoethyl benzene phenol polyoxy
Propylene polyoxyethylene block polymers）, agriculture breast 600#, one or more in agriculture breast 400# etc.；Antifreezing agent for example ethylene glycol, third
One or more in glycol, glycerine, urea, inorganic salts such as sodium chloride etc.；Thickener such as white carbon, polyvinyl alcohol, swelling
One or more in soil, aluminium-magnesium silicate etc.；Defoamer such as silicone oil, silicone compound, C10-20 saturated fat acids chemical combination
One or more in thing, C8-10 aliphatic alcohols, hexanol, butanol, octanol etc.；Water is deionized water.
To granule, spendable auxiliary agent has：Carrier such as clay, kaolin, talcum, calcium carbonate, cornstarch, alumina silicate
In one or more；One or more in dispersant such as polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate；Wetting
One or more in agent such as alkyl sulfate, alkylsulfonate, naphthalene sulfonate；Adhesive such as polyvinyl alcohol, dextrin, polyethylene
One or more in pyrrolidones etc..
To aqua, spendable auxiliary agent has：Emulsifying agent such as calcium dodecyl benzene sulfonate, alkylphenol-formaldehyde resin polyoxyethylene
Ether, agriculture breast 2201#, sorbitan monostearate, sorbitan monostearate APEO, octyl phenol polyoxyethylene
（10）Ether, AEO, phenethyl phenol polyoxyethylene poly-oxygen propylene aether, agriculture breast 600#, agriculture breast 400#, dodecane
One or more in base dimethyl benzyl ammonium chloride etc.；Water is deionized water.
Rationally, good disinsection effect, drug cost are low for instant component, and its activity and insecticidal effect are not each component activity
Simple superposition, but have significant synergistic effect, good to crop safety, meet the security requirement of pesticidal preparations.This
Bright have significantly to the Semipteras such as tea lesser leafhopper, thrips, diamondback moth, plant hopper, aphid, Thysanoptera, Lepidoptera, homoptera pest
Prevention effect.
Specific embodiment
Ring bromine insect amide and double wing of Tolfenpyrad or flonicamid mixture are described below by Toxicity Determination
Whether mesh, Thysanoptera, Lepidoptera, homoptera pest have synergistic effect.
1st, the joint toxicity measuring of ring bromine insect amide and Tolfenpyrad mixture to tea lesser leafhopper.
Toxicity Determination is carried out using infusion process.By ring bromine insect amide active compound, Tolfenpyrad active compound, being configured to 5 is
The liquid of row concentration, standby.
The tea lesser leafhopper for selecting indoor culture, age consistent（Empoasca pirisuga）Nymph, nymph is placed in cold
5～10 min in 0～4 DEG C of refrigerator are hidden, is taken out when its inertia, will be into the liquid for the leaching gently of the leaching worm cage with nymph,
Taking out after 10s, unnecessary liquid being sucked with blotting paper, marked respectively, it is (70 ± 10) % to be then placed in (26 ± 1) DEG C, relative humidity
Phenology case in, fed with the tealeaves blade of fresh clean.Each concentration processes nymph 30, is repeated 4 times, and contains respective amount to soak
0.1% Tween 80 water of acetone is control, 48h inspection results after medicine, and the control death rate is invalid test higher than 20%, test worm
Death standard is：Test worm is touched with little writing brush, 5 s nonresponders are considered as death, are otherwise considered as worm living.
According to investigation result, the death rate of each process is calculated.Obtain virulence regression equation, the lethal concentration of 50, coefficient correlation
Deng, and co-toxicity coefficient is obtained with the abundant methods of Sun Yun（CTC values）.
Joint of the Pesticidal combination of the insect amide of bromine containing ring that the present invention is provided to tea lesser leafhopper is evaluated using co-toxicity coefficient method
Effect, seeks regression equation with the logarithm and medicament of drug concentration to the preventive effect niqueMin of tea lesser leafhopper, and calculates medicament
To LC50Value, then tries to achieve co-toxicity coefficient.Synergy of the compound drug to tea lesser leafhopper is evaluated with co-toxicity coefficient, altogether poison
Coefficient>120 are expressed as synergistic effect, and co-toxicity coefficient is expressed as summation action, co-toxicity coefficient between 80～120<80 are expressed as
Antagonism.
1 ring bromine insect amide of table and toxicity test result of the Tolfenpyrad mixture to tea lesser leafhopper
Toxicity Determination result shows：Ring bromine insect amide presses 1 with Tolfenpyrad:60～60:1 uses with, and tea lesser leafhopper is had
Higher virulence, shows as synergistic effect.
2nd, the joint toxicity measuring of ring bromine insect amide and Tolfenpyrad mixture to eggplant thrips.
Toxicity Determination is carried out using infusion process.By ring bromine insect amide active compound, Tolfenpyrad active compound, being configured to 5 is
The liquid of row concentration, standby.
The onion thrips for selecting indoor culture, age consistent（Thrips alliorum), test worm is moved for 20 with pest sucking device
Enter in the leaching worm box that volume is 50mL, medication immersion worm 10s blots unnecessary liquid in leaching worm box with filter paper.It is put into the eggplant of long 3cm
Cotyledon, sealed membrane will soak the sealing of worm box, after be placed in temperature and be 26 DEG C, cultivate in the illumination box of humidity 70%.Often process and repeat
4 times, often repeat to soak worm 20, be processed as compareing with clear water.Check after 24h that number of dead and live insects, the control group death rate are less than 20%
Test as efficiency test.
According to investigation result, the death rate of each process is calculated.Obtain virulence regression equation, the lethal concentration of 50, coefficient correlation
Deng, and co-toxicity coefficient is obtained with the abundant methods of Sun Yun（CTC values）.
The Pesticidal combination that the insect amide of bromine containing ring that the present invention is provided is evaluated using co-toxicity coefficient method is made to the joint of eggplant thrips
With seeking regression equation with the logarithm and medicament of drug concentration to the preventive effect niqueMin of eggplant thrips, and calculate medicament pair
LC50Value, then tries to achieve co-toxicity coefficient.Synergy of the compound drug to eggplant thrips, co-toxicity coefficient are evaluated with co-toxicity coefficient>
120 are expressed as synergistic effect, and co-toxicity coefficient is expressed as summation action, co-toxicity coefficient between 80～120<80 are expressed as antagonism work
With.
2 ring bromine insect amide of table and toxicity test result of the Tolfenpyrad mixture to eggplant thrips
Toxicity Determination result shows：Ring bromine insect amide presses 1 with Tolfenpyrad:50～50:1 use with, eggplant thrips is had compared with
High virulence, shows as synergistic effect.
3rd, the joint toxicity measuring of ring bromine insect amide and Tolfenpyrad mixture to diamondback moth.
Toxicity Determination is carried out using spray-on process.By ring bromine insect amide active compound, Tolfenpyrad active compound, being configured to 5 is
The liquid of row concentration, standby.
The wild cabbage diamondback moth for selecting indoor culture, age consistent（Plutella xylostella), life is dipped with writing brush
The test worm 15 of reason state consistency is put into culture dish, then culture dish is placed in Potter spraying tower chassis carries out metered dose, sprays
Liquid measure is 1ml, takes out test worm, raised after liquid sedimentation 1in.Test worm after by process is placed in temperature for 26 DEG C, humidity
70%, periodicity of illumination is L:D=（16:8）Raise under conditions of h.Often process and be repeated 4 times, be processed as compareing with clear water.Examine after 48h
Number of dead and live insects is looked into, test of the control group death rate less than 20% is efficiency test.
According to investigation result, the death rate of each process is calculated.Obtain virulence regression equation, the lethal concentration of 50, coefficient correlation
Deng, and co-toxicity coefficient is obtained with the abundant methods of Sun Yun（CTC values）.
Joint of the Pesticidal combination of the insect amide of bromine containing ring that the present invention is provided to wild cabbage diamondback moth is evaluated using co-toxicity coefficient method
Effect, seeks regression equation with the logarithm and medicament of drug concentration to the preventive effect niqueMin of wild cabbage diamondback moth, and calculates medicament
To LC50Value, then tries to achieve co-toxicity coefficient.Synergy of the compound drug to diamondback moth, co-toxicity coefficient are evaluated with co-toxicity coefficient>
120 are expressed as synergistic effect, and co-toxicity coefficient is expressed as summation action, co-toxicity coefficient between 80～120<80 are expressed as antagonism work
With.
3 ring bromine insect amide of table and toxicity test result of the Diacloden mixture to diamondback moth
Toxicity Determination result shows：Ring bromine insect amide presses 1 with Diacloden:50～50:1 use with, wild cabbage diamondback moth is had compared with
High virulence, shows as synergistic effect.
4th, ring bromine insect amide and flonicamid mixture are determined to the synergy of planthopper.
Synergy measure is carried out using rice-stem dipping method.By ring bromine insect amide active compound, flonicamid active compound, it is configured to
The liquid of 5 series concentrations, standby.
Select the planthopper of indoor feeding（Nilaparvata lugens）3 age nymphs are standby.Cultivate choice experiment room
Healthy and strong consistent tillering stage rice seedlings, even root take, clean, be cut into the band root rice stem of about 10cm length, dry in the air to table in shady place
Face is without washmarking, stand-by.
Ready rice stem is impregnated in the liquid for preparing 30s, taking-up is dried, root guarantor is encased with wet absorbent cotton
Wet, outsourcing preservative film is placed in test tube, per 3 plants of test tube.4 repetitions are often processed, and process without medicament are set as control.
Test worm is moved in test tube with pest sucking device, per 15, test tube, the mouth of pipe is covered with gauze.
After process test worm as（25±1）DEG C, relative humidity be 60%～80%, the illumination photoperiod be L:D=（16:8）H bars
Raise under part and observe.After process, 48h investigation test worm death condition, records total borer population and dead borer population.According to investigation result, calculate
Each death rate for processing.Virulence regression equation, the lethal concentration of 50, coefficient correlation etc. is obtained, and common poison system is obtained with the abundant methods of Sun Yun
Number（CTC values）.
Synergy of the Pesticidal combination of the insect amide of bromine containing ring that the present invention is provided to planthopper is evaluated using co-toxicity coefficient method,
Regression equation is asked to the preventive effect niqueMin of planthopper with the logarithm and medicament of drug concentration, and calculates the LC of medicament pair50Value,
Then co-toxicity coefficient is tried to achieve.Synergy of the compound drug to planthopper, co-toxicity coefficient are evaluated with co-toxicity coefficient>120 are expressed as
Synergistic effect, co-toxicity coefficient are expressed as summation action, co-toxicity coefficient between 80～120<80 are expressed as antagonism.
4 ring bromine insect amide of table and toxicity test result of the flonicamid mixture to planthopper
Toxicity Determination result shows：Ring bromine insect amide presses 1 with flonicamid:60～60:1 use with, planthopper is had compared with
High virulence, shows as synergistic effect.
5th, the joint toxicity measuring of ring bromine insect amide and flonicamid mixture to Cucumber blight.
Toxicity Determination is carried out using dip method.By ring bromine insect amide active compound, flonicamid active compound, 5 are configured to
The liquid of series concentration, standby.
The cotten aphid for selecting indoor culture, age consistent（Aphis gossypii）Target insect is immersed liquid by nymph
After 10s, unnecessary liquid is drawn with filter paper, test worm is transferred under normal condition and is raised, often processed and be repeated 4 times, often repeat to soak worm
10, it is processed as compareing with clear water.Check after 24h that number of dead and live insects, test of the control group death rate less than 20% are effectively examination
Test.
According to investigation result, the death rate of each process is calculated.Obtain virulence regression equation, the lethal concentration of 50, coefficient correlation
Deng, and co-toxicity coefficient is obtained with the abundant methods of Sun Yun（CTC values）.
The Pesticidal combination that the insect amide of bromine containing ring that the present invention is provided is evaluated using co-toxicity coefficient method is made to the joint of Cucumber blight
With seeking regression equation with the logarithm and medicament of drug concentration to the preventive effect niqueMin of Cucumber blight, and calculate medicament pair
LC50Value, then tries to achieve co-toxicity coefficient.Synergy of the compound drug to Cucumber blight, co-toxicity coefficient are evaluated with co-toxicity coefficient>
120 are expressed as synergistic effect, and co-toxicity coefficient is expressed as summation action, co-toxicity coefficient between 80～120<80 are expressed as antagonism work
With.
5 ring bromine insect amide of table and toxicity test result of the flonicamid mixture to Cucumber blight
Toxicity Determination result shows：Ring bromine insect amide presses 1 with flonicamid:60～60:1 uses with, and Cucumber blight is had
Higher virulence, shows as synergistic effect.
Present invention is described further with reference to embodiment.
Example of formulations 1
Weigh 50 grams of ring bromine insect amides, 80 grams of Tolfenpyrads, 40 grams of agriculture breasts 500#, 60 grams of agriculture breasts 400#, 45 grams of agriculture breasts 600#,
280 grams of dimethylformamides, dimethylbenzene add to 1000 gram weight parts.Above-mentioned raw materials are blended, and stirring and dissolving is obtained 13% completely afterwards
Ring bromine insect amide Tolfenpyrad missible oil.
Example of formulations 2
Weigh 100 grams of ring bromine insect amides, 140 grams of flonicamids, 60 grams of agriculture breasts 500#, 40 grams of TX-10,50 grams of agriculture breasts 1601#,
110 grams of ethyl acetate, biodiesel add to 1000 gram weight parts.Above-mentioned raw materials are blended, and stirring and dissolving is obtained 24% ring completely afterwards
Bromine insect amide flonicamid missible oil.
Example of formulations 3
Weigh 60 grams of ring bromine insect amides, 100 grams of Tolfenpyrads, 40 grams of TERSPERSE2020（Huntsman Corporation of the U.S. produces）、30
Gram agriculture breast 1601#, 18 grams of sodium naphthalene sulfonates, 15 grams of aluminium-magnesium silicates, 12 grams of aluminium-magnesium silicates, 8 grams of ethylene glycol, 12 grams of benzoic acid, 10 grams
Organic silicon defoamer（Trade name：S-29 Nanjing "four news" (new ideas applied chemistry product company produces）, 10 grams of epoxychloropropane, deionized water adds
To 1000 gram weight parts.Above-mentioned raw materials are blended, and high speed shear disperses 30min, with making 16% ring bromine worm acyl after sand mill sand milling
Amine Tolfenpyrad suspending agent.
Example of formulations 4
Weigh 160 grams of ring bromine insect amides, 60 grams of flonicamids, 40 grams of TERSPERSE2020（Huntsman Corporation of the U.S. produces）、
25 grams of agriculture breasts 1601#, 10 grams of sodium naphthalene sulfonates, 23 grams of aluminium-magnesium silicates, 10 grams of aluminium-magnesium silicates, 20 grams of ethylene glycol, 12 grams of benzoic acid, 6
Gram organic silicon defoamer s-29（Nanjing "four news" (new ideas applied chemistry product company produces）, 8 grams of epoxychloropropane, deionized water adds to 1000
Gram weight part.Above-mentioned raw materials are blended, and high speed shear disperses 30min, with prepared 22% ring bromine insect amide fluorine after sand mill sand milling
Pyridine insect amide suspending agent.
Example of formulations 5
Weigh 150 grams of ring bromine insect amides, 200 grams of Tolfenpyrads, 60 grams of calcium lignosulfonates, 40 grams of alkyl naphthalene formaldehyde condensation product sulphurs
Sour sodium, 40 grams of sodium alkyl sulfonates, potter's clay are filled up to 1000 grams of weight portion.Above-mentioned raw materials are blended, ultra micro air-flow crushing, mixing
Processing step is prepared into 35% ring bromine insect amide Tolfenpyrad wettable powder.
Example of formulations 6
Weigh 250 grams of ring bromine insect amides, 50 grams of flonicamids, 30 grams of alkylphenol-polyethenoxy base ether sulfonic acid calcium, 40 grams of alkyl
Naphthalenesulfonate formaldehyde condensation compound, 35 grams of Negels, talcum powder are filled up to 1000 grams of weight portion.Above-mentioned raw materials are through mixed
Conjunction, ultra micro air-flow crushing, hybrid technique step are prepared into 30% ring bromine insect amide flonicamid wettable powder.
Example of formulations 7
Weigh 200 grams of ring bromine insect amides, 150 grams of Tolfenpyrads, 30 grams of GY-D06,25 grams of sodium lignin sulfonates, 25 grams of pull open powders
BX（Nekal）, 25 grams of K-12（Lauryl sodium sulfate）, fine particle calcium carbonate adds to 1000 gram weight parts.Above-mentioned raw materials are frequent
The method of regulation water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step produce 35% ring bromine insect amide azoles
Insect amide water dispersible granules.
Example of formulations 8
Weigh 140 grams of ring bromine insect amides, 260 grams of flonicamids, 50 grams of GY-D06（Polycarboxylate, Huntsman Corporation of the U.S. go out
Product）, 30 grams of sodium lignin sulfonate, 35 grams of lauryl sodium sulfate, 20 grams of alkylsulfonate sodium, talcum powder adds to 1000 gram weights
Part.The method of above-mentioned raw materials frequent regulation water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step produce 40%
Ring bromine insect amide flonicamid water dispersible granules.
Example of formulations 9
Weigh 100 grams of ring bromine insect amides, 60 grams of Tolfenpyrads, 30 grams of this disk -60#, 25 grams of triphenoethyl benzene phenol polyethenoxy ethers
Phosphate, 30 grams of Tween-60 #, 30 grams of Nongru-700 #, 45 grams of glycerine, 60 grams of solvent naphtha S-200,40 grams of toluene, 4 grams of bentonites,
5 grams of Sodium Benzoates, deionized water add to 1000 gram weight parts.Above-mentioned raw materials are blended, and high speed shearing emulsification is obtained 16% ring bromine worm
Acid amides Tolfenpyrad aqueous emulsion.
Example of formulations 10
Weigh 40 grams of ring bromine insect amides, 80 grams of flonicamids, 30 grams of Nonyl phenos（EO=10）Ether phosphate, 20 grams
Nongru-700 #, 30 grams of agriculture breasts, 1601,20 grams of Tween-60 #, 13 grams of epoxidized soybean oils, 20 grams of glycerine, 25 grams of cyclohexanone, 4 grams of swellings
Soil, 4 grams of Sodium Benzoates, deionized water add to 1000 gram weight parts.Above-mentioned raw materials are blended, and high speed shearing emulsification is obtained 12% ring
Bromine insect amide flonicamid aqueous emulsion.
Example of formulations 11
Weigh 60 grams of ring bromine insect amides, 20 grams of Tolfenpyrads, 45 grams of agriculture breasts, 2201,35 grams of this disk-60#, 40 grams of polysorbate60-#, 80
Gram 1-METHYLPYRROLIDONE, 120 grams of cyclohexanone, 25 grams of n-butanols, 20 grams of epoxychloropropane, completely and are well mixed through dissolving,
Deionized water adds to 1000 gram weight parts, and 8% ring bromine insect amide Tolfenpyrad microemulsion is obtained after stirring.
Example of formulations 12
Weigh 30 grams of ring bromine insect amides, 70 grams of flonicamids, 50 grams of agriculture breasts, 2201,40 grams of this disk-60#, 45 grams of polysorbate60-#,
60 grams of 1-METHYLPYRROLIDONEs, 110 grams of cyclohexanone, 50 grams of n-butanols, 15 grams of epoxychloropropane, completely and mix through dissolving
Even, deionized water adds to 1000 gram weight parts, and 10% ring bromine insect amide flonicamid microemulsion is obtained after stirring.
Example of formulations 13
Weigh 20 grams of ring bromine insect amides, 30 grams of Tolfenpyrads, 50 grams of propane diols, 40 grams of agriculture breasts 600#, 20 grams of white carbons, 25 grams pungent
Alcohol, deionized water are filled up to 1000 grams of weight portion.5% ring bromine worm acyl is obtained after the blended stirring of above-mentioned raw materials, polymerisation
Amine Tolfenpyrad microcapsule formulations.
Example of formulations 14
Weigh 10 grams of ring bromine insect amides, 20 grams of flonicamids, 40 grams of glycerine, 60 grams of agriculture breasts 2201#, 24 grams of bentonites, 18 grams
Butanol, deionized water are filled up to 1000 grams of weight portion.3% ring bromine worm is obtained after the blended stirring of above-mentioned raw materials, polymerisation
Acid amides flonicamid microcapsule formulations.
Example of formulations 15
Weigh 30 grams of ring bromine insect amides, 10 grams of Tolfenpyrads, 35 grams of polycarboxylic acids sodium, 40 grams of sodium naphthalene sulfonates, 28 grams of polyvinyl alcohol, carbon
Sour calcium adds to 1000 gram weight parts.Above-mentioned raw materials are well mixed in mixed cylinder, through extruding, granulation, are dried, and screened step
4% ring bromine insect amide Tolfenpyrad granule is obtained suddenly.
Example of formulations 16
Weigh 50 grams of ring bromine insect amides, 20 grams of flonicamids, 45 grams of Negels, 35 grams of sodium alkyl sulfonates, 28 grams gather
Vinylpyrrolidone, calcium carbonate add to 1000 gram weight parts.Above-mentioned raw materials are well mixed in mixed cylinder, through extruding, granulating,
Dry, and screened step is obtained 7% ring bromine insect amide flonicamid granule.
Example of formulations 17
70 grams of ring bromine insect amides, 30 grams of Tolfenpyrads, 25 grams of agriculture breasts 2201#, 35 grams of Nongru-700 # are weighed, deionized water is added to
1000 gram weight parts.Above-mentioned raw materials are blended, and stirring and dissolving is obtained 10% ring bromine insect amide Tolfenpyrad aqua completely afterwards.
Example of formulations 18
60 grams of ring bromine insect amides, 20 grams of flonicamids, 30 grams of agriculture breasts 1601# are weighed, deionized water adds to 1000 gram weight parts.
Above-mentioned raw materials are blended, and stirring and dissolving is obtained 8% ring bromine insect amide flonicamid aqua completely afterwards.
Biological Examples 1：Preventing and treating eggplant thrips field control effectiveness test.
Inventor has carried out example of formulations 1 in 2015 in Hainan Province Sanya precipice city（13% ring bromine insect amide azoles
Insect amide missible oil）, example of formulations 3（16% ring bromine insect amide Tolfenpyrad suspending agent）, example of formulations 5（35% ring bromine worm
Acid amides Diacloden wettable powder）Preventing and treating eggplant thrips field control effectiveness test, demonstrates preventing and treating of the medicament to eggplant thrips
Effect and the security to eggplant.
Trial crops are eggplant, and controlling object is eggplant thrips, sprays in eggplant thrips 2 age nymph occurance peak.Test
Field gesture is flat, and soil is sandy loam, and middle fertility, irrigation and drainage are facilitated.Test medicine and dosage refer to table 6.Separately blank is set,
Often process repeats for 4 times, every cell 30, totally 24 cells, the random district's groups arrangement of cell.
Fix in eggplant middle and upper part per cell and choose 20 leaves, insect population investigation is carried out before dispenser, 5 days and 10 after dispenser
Its investigation residual borer population living.Calculate larval mortality and prevention effect.
CK0：Borer population living before blank district dispenser, unit is head；
CK1：Borer population living after blank district dispenser, unit is head；
PT0：Borer population living before chemicals treatment district dispenser, unit is head；
PT1：Borer population living after chemicals treatment district dispenser, unit is head.
Eggplant thrips field control effectiveness test result prevented and treated by table 6
Field control effectiveness test result shows, complex preparation preventive effect of 10 days after medicine has exceeded 90%, and the preventive effect of two single doses
Respectively 69.0% and 65.1%, after illustrating ring bromine insect amide and Tolfenpyrad respectively in different ratio compoundings, the preventive effect of preparation
Obvious apparently higher than the preventive effect of two single doses, synergistic effect.
Security survey, observes during test, and all reagent agents occur without poisoning phenomenon to eggplant growth safety.
Example of formulations 7,9,11,13,15,17, preventing and treating eggplant thrips table of field test results are bright, and after medicine, 10 days preventive effects are equal
Reach more than 90%, hence it is evident that better than ring bromine insect amide, the preventive effect 61.4% of Tolfenpyrad single dose, 63.5%, 65.8%, 64.6%,
60.7% and 68.2%.
Biological Examples 2：Preventing and treating planthopper field control effectiveness test.
Inventor has carried out example of formulations 8 in Junichiro Koizumi village of the county of xiangtan, hunan province in 2015（40% ring bromine insect amide fluorine pyridine
Insect amide water dispersible granules）, example of formulations 10（12% ring bromine insect amide flonicamid aqueous emulsion）, example of formulations 12
（10% ring bromine insect amide flonicamid microemulsion）Preventing and treating planthopper field control effectiveness test, demonstrates the medicament to planthopper
Prevention effect and the security to paddy rice.
Trial crops are paddy rice, and controlling object is planthopper, spray in planthopper 2 age nymph occurance peak.Test field
Gesture is flat, and soil is sandy loam, and middle fertility, irrigation and drainage are facilitated.Test medicine and dosage refer to table 7.Blank is separately set, is often located
Reason repeats for 4 times, every cell 30, totally 24 cells, the random district's groups arrangement of cell.
Insect population investigation is carried out before dispenser, investigation in 7 and 14 days after dispenser remains borer population living.Jumped using interlacing per cell
15 points of samplings of method, investigate 30 clumps altogether by 2 clumps per.Basin to be clapped and remain borer population living after insect population and medicine before recording medicine, calculates larva dead
Rate of dying and prevention effect.
Planthopper field control effectiveness test result prevented and treated by table 7
Field control effectiveness test result shows that complex preparation preventive effect of 14 days after medicine has exceeded 90%, and 14 days after medicine, single dose
Preventive effect be respectively 67.5% and 65.8%, after illustrate that ring bromine insect amide and flonicamid are compounded in different ratio, preparation
Preventive effect is obvious apparently higher than the preventive effect of two single doses, synergistic effect.
Security survey, observes during test, and all reagent agents occur without poisoning phenomenon to paddy growth safety.
Example of formulations 2,4,6,16,18, preventing and treating planthopper table of field test results are bright, and after medicine, 10 days preventive effects reach
More than 90%, hence it is evident that better than ring bromine insect amide, the preventive effect 69.6%, 61.7%, 64.3%, 68.2%, 63.5% of flonicamid single dose
With 65.2%.
From above example, ring bromine insect amide is 1 with Tolfenpyrad, flonicamid according to weight ratio:60～
60:1 is compounded, can be made into missible oil, suspending agent, wettable powder, water dispersible granules, aqueous emulsion, microemulsion, microcapsule formulations,
Granule, aqua, to the Semipteras such as tea lesser leafhopper, thrips, diamondback moth, plant hopper, aphid, Thysanoptera, Lepidoptera, Homoptera evil
Worm has significant prevention effect, synergistic effect substantially, to reduce dosage and drug cost, and to crop safety, is preventing and treating half
Wing mesh, Thysanoptera, Lepidoptera, the favourable agents of homoptera pest, therefore have wide practical use in production.
In sum, composition of the invention is that its activity and insecticidal effect are not using two kinds of active components compound scheme
It is the simple superposition of each component activity, compared with existing unitary agent, in addition to obvious insecticidal effect, and has significantly
Synergistic effect, cost accounting reduce, to crop safety, meet the security requirement of pesticidal preparations.
Claims (5)
1. a kind of Pesticidal combination containing ring bromine insect amide, it is characterised in that effective active composition is by the first active component ring
Bromine insect amide and the second active component Tolfenpyrad or a kind of composition in flonicamid, the first active component and the second activity
The weight ratio of composition is 1:60～60:1, content sum is the 1%～80% of the composition total weight.
2. the Pesticidal combination according to claim 1 containing ring bromine insect amide, it is characterised in that the first active component and
Two active component weight ratios are 1:30～30:1, content sum is the 5%～60% of the composition total weight.
3. the Pesticidal combination according to claim 1 containing ring bromine insect amide, it is characterised in that the combination dosage form is
Missible oil, suspending agent, wettable powder, water dispersible granules, aqueous emulsion, microemulsion, microcapsule formulations, granule, aqua.
4. the Pesticidal combination according to claim 1 containing ring bromine insect amide preventing and treating Semiptera, Thysanoptera, Lepidoptera,
Purposes on homoptera pest.
5. the Pesticidal combination according to claim 5 containing ring bromine insect amide is in preventing and treating tea lesser leafhopper, thrips, pickles
Purposes on moth, plant hopper, aphid.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112237194A (en) * | 2019-07-19 | 2021-01-19 | 青岛奥迪斯生物科技有限公司 | Insecticidal composition containing cyclic bromoantraniliprole |
| CN113519534A (en) * | 2021-07-24 | 2021-10-22 | 上海明德立达生物科技有限公司 | Insecticidal composition containing brofenbendiamide and flonicamid and application thereof |
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| JP2008019222A (en) * | 2006-07-14 | 2008-01-31 | Ishihara Sangyo Kaisha Ltd | Anthranylamide-based compound, method for producing the same, and pest-controlling agent comprising the same |
| CN101557710A (en) * | 2006-12-14 | 2009-10-14 | 石原产业株式会社 | Pesticidal compositions |
| CN105901007A (en) * | 2016-06-08 | 2016-08-31 | 成都科利隆生化有限公司 | Pesticidal composition containing cyclaniliprole and chloropyridine |
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2016
- 2016-10-12 CN CN201610888199.5A patent/CN106489951A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008019222A (en) * | 2006-07-14 | 2008-01-31 | Ishihara Sangyo Kaisha Ltd | Anthranylamide-based compound, method for producing the same, and pest-controlling agent comprising the same |
| CN101557710A (en) * | 2006-12-14 | 2009-10-14 | 石原产业株式会社 | Pesticidal compositions |
| CN105901007A (en) * | 2016-06-08 | 2016-08-31 | 成都科利隆生化有限公司 | Pesticidal composition containing cyclaniliprole and chloropyridine |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112237194A (en) * | 2019-07-19 | 2021-01-19 | 青岛奥迪斯生物科技有限公司 | Insecticidal composition containing cyclic bromoantraniliprole |
| CN112237194B (en) * | 2019-07-19 | 2023-10-20 | 青岛奥迪斯生物科技有限公司 | Insecticidal composition containing cycloartemia |
| CN113519534A (en) * | 2021-07-24 | 2021-10-22 | 上海明德立达生物科技有限公司 | Insecticidal composition containing brofenbendiamide and flonicamid and application thereof |
| CN113519534B (en) * | 2021-07-24 | 2022-02-25 | 上海明德立达生物科技有限公司 | Insecticidal composition containing brofenbendiamide and flonicamid and application thereof |
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