CN110115268B - Pesticide composition containing tolfenpyrad and fluopyram - Google Patents

Pesticide composition containing tolfenpyrad and fluopyram Download PDF

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CN110115268B
CN110115268B CN201910422532.7A CN201910422532A CN110115268B CN 110115268 B CN110115268 B CN 110115268B CN 201910422532 A CN201910422532 A CN 201910422532A CN 110115268 B CN110115268 B CN 110115268B
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fluopyram
tolfenpyrad
root
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pesticide composition
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CN110115268A (en
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罗建军
翁群芳
胡琼波
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South China Agricultural University
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles

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  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
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Abstract

The invention discloses a pesticide composition containing tolfenpyrad and fluopyram, belonging to the technical field of pesticides, and the active ingredients of the composition comprise tolfenpyrad and fluopyram, wherein the ratio of tolfenpyrad to fluopyram is 1: 40-60: 1. The pesticide composition is applied to the target crops through a reasonable preparation, can effectively prevent and treat insect pests on the target crops, and also can prevent and treat diseases, such as phyllotreta striolata on carrots, and meanwhile, can prevent and treat root-knot nematodes of carrots, and is time-saving and labor-saving.

Description

Pesticide composition containing tolfenpyrad and fluopyram
Technical Field
The invention belongs to the technical field of pesticides, and particularly relates to a pesticide composition containing tolfenpyrad and fluopyram.
Background
Carrot yellow flea beetle is harmful: both adults and larvae can be harmful. The adult bites the leaves and causes many small holes, especially the tender part, which often causes the seedlings to stop growing and even the whole plant to die. The buds and young pods of the seed plants can also be damaged. The larva damages the root, and moths the vegetable root epidermis into a plurality of curved insect paths, bites off the fibrous root, and leads the leaves on the ground to be yellow and wilted to die. After the fleshy roots of the carrots are damaged, the surfaces of the carrots are damaged into a plurality of black spots, and finally the carrots become black and rot. In addition, wounds caused by adults and larvae are prone to spread soft rot.
Carrot is invaded by meloidogyne incognita (Merloidogyneinogata), carrot meloidogyne is caused, when the disease is light, overground parts have no obvious symptoms, when the disease is serious, a plant is pulled up, the phenomenon that fleshy roots become small and deformed, a plurality of fibrous roots are provided, and a plurality of cucurbit-shaped root knots are formed on the fibrous roots can be seen. The overground part shows poor growth, dwarfing, etiolation and wilting, and is similar to the symptoms of lack of fertilizer and water or blight, and plants die when the overground part is serious.
Tolfenpyrad (tolfenpyrd), cas.no: 129558-76-5, chemical name: IUPAC 4-chloro-3-ethyl-1-methyl-N- { [4- (4-methylphenoxy) phenyl ] -methyl } -1H-pyrazole-5-carboxamide belongs to a novel pyrazole heterocycle high-efficiency insecticidal and acaricidal agent. The mechanism of action is to block the electron transport system complex I in the metabolic system of mitochondria, thereby blocking the electron transport and preventing insects from supplying and storing energy, and is called mitochondrial electron transport complex inhibitor (METI). The tolfenpyrad has the characteristics of high efficiency, good quick-acting property, broad insecticidal spectrum and the like, has special effects on various pests and mites of Lepidoptera, Thysanoptera, Coleoptera, Homoptera, Diptera, Hemiptera and the like, particularly has good quick-acting property and long lasting period on plutella xylostella in the whole growth period, and has good effect on plutella xylostella which has resistance to conventional pesticides. In addition, the pesticide has wide application range, and can be applied to pest control of crops, vegetables, fruit trees, flowers, tea leaves and other crops.
Fluopyram, english name (ISO): fluopyram, trade name: luofida, CAS NO: 658066-35-4, chemical name: n- {2- [ 3-chloro-5- (trifluoromethyl) -2-pyridinyl ] ethyl-aaa-o-trifluoromethylbenzamide }; fluopyram is a succinate dehydrogenase inhibitor (SDHI) type sterilization nematicide developed by Bayer crop science, has good control effects on alternaria leaf spot, gray mold, powdery mildew, sclerotinia sclerotiorum, damping off, root rot, damping-off, early blight and the like on vegetables, fruit trees, field crops and the like, and is an efficient, green and low-toxicity sterilization nematicide found to have good control effects on various nematodes.
The compounding use of tolfenpyrad and fluopyram and the application of the compound composition of tolfenpyrad and fluopyram in preventing and treating carrot root-knot nematode and phyllotreta striolata are not reported at present.
Disclosure of Invention
The invention aims to provide a pesticide composition with obvious synergistic effect and wide control spectrum.
The invention also aims to provide application of the pesticide composition in preventing or controlling agricultural disease and pests, such as phyllotreta striolata, diamond back moth, asparagus caterpillar, prodenia litura, thrips, root-knot nematode, gray mold, powdery mildew, sclerotinia rot, damping off, root rot, damping off, early blight and the like.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
the active ingredients of the pesticide composition comprise tolfenpyrad and fluopyram, wherein the weight ratio of tolfenpyrad to fluopyram is 1: 40-60: 1, preferably 1: 20-30: 1, more preferably 1: 10-15: 1, and most preferably 4:3, 3:1, 9:5, 5:6, 2:1 and 7: 6.
The weight percentage of the sum of the tolfenpyrad and the fluopyram in the pesticide composition is 6-65%, preferably 10-45%.
The pesticide composition provided by the invention comprises the active ingredients of tolfenpyrad and fluopyram and other agriculturally acceptable auxiliary ingredients, and the composition is prepared into any dosage form suitable for agricultural production by using a conventional pesticide preparation processing method.
Preferably, the dosage form includes, but is not limited to, water dispersible granules, wettable powders, extruded granules, coated granules, suspending agents, microemulsions, aqueous emulsions, suspended seed coatings, microcapsule suspending agents.
The auxiliary ingredients are known substances which are agriculturally acceptable and are beneficial to the stability of the active ingredients of the composition in storage and use and the exertion of the drug effect, and include but are not limited to solvents, emulsifiers, dispersants, wetting agents, binders, disintegrants, thickeners, preservatives, antifoaming agents, antifreeze agents, stabilizers, wall materials, coating agents, fillers.
The solvent may be one or more of acetone, butanone, cyclohexanone, xylene, trimethylbenzene, methylnaphthalene, methyl oleate, ethyl acetate, fatty acid methyl ester, N-dimethylacetamide, deionized water, and the like.
The emulsifier can be one or more of tristyrylphenol polyoxyethylene polyoxypropylene ether, Nongru 400, Nongru 500, Nongru 600, Nongru 700, Ningru 31, Ningru 33 and Ningru 37.
The dispersant may be one or more of polycarboxylate, lignosulfonate, alkylnaphthalenesulfonate, sodium polyacrylate, methylenedinaphthalenesulfonate, calcium alkylbenzenesulfonate, amine alkylbenzenesulfonate, carboxymethylcellulose, polyvinyl alcohol, polyvinylpyrrolidone, sodium tripolyphosphate, and alkylnaphthalenesulfonate polycondensate.
The wetting agent can be one or more of secondary alkyl sodium sulfate, fatty alcohol-polyoxyethylene ether, lauryl sodium sulfate, nonylphenol polyoxyethylene ether, sorbitan fatty acid ester polyoxyethylene ether, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkylphenol polyoxyethylene ether phosphate, phenethyl phenol polyoxyethylene ether phosphate, alkyl sulfate, alkyl sulfonate and naphthalene sulfonate.
The binder can be one or more of polyvinyl alcohol, dextrin, polyvinylpyrrolidone, glucose, sucrose, hydroxyethyl cellulose, soluble starch, and polyethylene glycol.
The disintegrating agent can be one or more of polyvinylpyrrolidone, sodium alginate, calcium chloride, sodium chloride, magnesium chloride, and aluminum chloride.
The thickener can be one or more of xanthan gum, gelatin, arabic gum, polyvinyl alcohol, bentonite, and magnesium aluminum silicate.
The preservative may be one or more of formaldehyde, benzoic acid, sodium benzoate, potassium sorbate, kamazone, isothiazolinone.
The defoaming agent can be silicone oil, silicone compound, C10-20Saturated fatty acid compound, C8-10One or more of fatty alcohols.
The antifreezing agent can be one or more of sorbitol, ethylene glycol, propylene glycol, glycerol, polyethylene glycol, sorbitol and urea.
The stabilizer can be one or more of resorcinol, epoxidized soybean oil, epichlorohydrin and epoxidized linseed oil.
The capsule wall material can be one or more of polyurethane, poly toluene-2, 4-diisocyanate, polypropylene acetate, cellulose phthalate, polyacrylate, polyamide, multifunctional aminoplast, ethyl cellulose, hydroxyethyl cellulose, ethylenediamine, sodium polystyrene sulfonate and the like.
The coating agent can be one or more of polyvinyl alcohol, polyvinylpyrrolidone, polyester resin, acrylic acid synthetic polymer, acrylic acid resin film forming agent, butadiene resin film forming agent, polyurethane film forming agent and nitrocellulose film forming agent.
The filler can be one or more of white carbon black, kaolin, bentonite, attapulgite, light calcium carbonate, gypsum, urea, sucrose, diatomite, ammonium sulfate, monopotassium phosphate, argil and sepiolite.
Optionally, the composition may also comprise other additional components, such as protective colloids, synergists, thixotropic agents, penetrants, dyes, masking agents.
The mode of application of the pesticidal composition of the present invention is selected depending on the target object and the environment of use, and includes separate, sequential or simultaneous application of tolfenpyrad and fluopyram, and further includes any of stem application, root application, soil application or foliar application, such as root irrigation, seed dressing, broadcasting and the like, of the pesticidal composition of the present invention at an agronomically effective and substantially non-phytotoxic application rate.
The amount of the agricultural chemical composition of the present invention to be applied varies depending on the mixing ratio of the active ingredients, weather conditions, form of the chemical, application period, application method, application place, control subject, and the like.
The compositions of the present invention may also be applied in combination with other active ingredients such as fungicides, bactericides, attractants, insecticides, acaricides, nematicides, growth regulators, herbicides, safeners, fertilizers or semiochemicals and the like.
The pesticide composition is used for preventing or controlling agricultural pests.
Preferably, the agricultural pests are root knot nematodes of carrot and striped flea beetles.
Compared with the prior art, the invention has the beneficial effects that:
(1) the pesticide composition is applied to the target crops through a reasonable preparation, can effectively prevent and treat insect pests on the target crops, and also can prevent and treat diseases, such as phyllotreta striolata on carrots, and meanwhile, can prevent and treat root-knot nematodes of carrots, and is time-saving and labor-saving.
(2) The pesticide composition has the advantages that through reasonable compounding of the active ingredients, the control effect is obviously improved compared with that of a single active ingredient, the synergistic effect is realized, the use amount of the active ingredients is further reduced, and the environmental pollution is reduced.
(3) Tolfenpyrad belongs to a novel pyrazole heterocyclic high-efficiency insecticidal and acaricidal agent, fluopyram is a bactericidal and nematicidal agent, the two are novel in compounding, the generation of pest resistance is overcome or delayed while the synergistic effect is achieved, and the application life of pesticide active ingredients is prolonged.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more concise and clear, the present invention is described with the following specific embodiments, but the present invention is by no means limited to these embodiments. The following description is only a preferred embodiment of the present invention, and is only for the purpose of describing the present invention, and should not be construed as limiting the scope of the present invention. It should be understood that any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.
First, preparation examples
Example 1: 35% tolfenpyrad-fluopyram microcapsule suspending agent (4:3)
Figure BDA0002065460490000051
Figure BDA0002065460490000061
The preparation method of the microcapsule suspending agent comprises the following steps: the materials are mixed and stirred according to a certain proportion, and after polymerization reaction, the 35 percent tolfenpyrad-fluopyram microcapsule suspending agent can be prepared.
Example 2: extruded granules of 40% tolfenpyrad-fluopyram (3:1)
Figure BDA0002065460490000062
The preparation method of the extruded granules comprises the following steps: mixing the active ingredient with the adjuvant and grinding, wetting the mixture with water, extruding the mixture, and drying in an air stream to obtain 40% extruded tolfenpyrad-fluopyram granules.
Example 3: 28% Tolfenpyrad Fluopyram coated granule (9:5)
Figure BDA0002065460490000063
The preparation method of the coated granule comprises the following steps: uniformly coating the ground active ingredients on a carrier wetted by polyethylene glycol in a mixer to obtain 28% of the tolfenpyrad-fluopyram coated granules.
Example 4: 55% tolfenpyrad-fluopyram wettable powder (5:6)
Figure BDA0002065460490000064
Figure BDA0002065460490000071
The preparation method of the wettable powder comprises the following steps: the 55 percent tolfenpyrad-fluopyram wettable powder is prepared by uniformly mixing the active ingredients, the dispersing agent, the wetting agent, the water and the like according to the proportion of the formula and grinding and/or shearing at a high speed.
Example 5: 6% Tolfenpyrad-Fluopyram suspension seed coating agent (2:1)
Figure BDA0002065460490000072
The preparation method of the suspension seed coating agent comprises the following steps: mixing all the auxiliary agents according to the formula, uniformly mixing by high-speed shearing, adding the active ingredients, continuously uniformly mixing by shearing, and then grinding in a horizontal sand mill to ensure that the particle size of the preparation is below 5 mu m, thus obtaining the 6 percent tolfenpyrad-fluopyram suspension seed coating agent.
Example 6: 41% tolfenpyrad-fluopyram water dispersible granule (1:40)
Figure BDA0002065460490000073
Figure BDA0002065460490000081
The preparation method of the water dispersible granule comprises the following steps: the materials are mixed according to a proportion, and after airflow crushing and uniform mixing, kneading granulation, drying and screening, the 44% tolfenpyrad-fluopyram water dispersible granule can be prepared.
Example 7: 61% tolfenpyrad-fluopyram water dispersible granule (60:1)
Figure BDA0002065460490000082
The preparation method of the water dispersible granule comprises the following steps: the materials are mixed according to a proportion, and after airflow crushing and uniform mixing, kneading granulation, drying and screening, the 61% tolfenpyrad-fluopyram water dispersible granule can be prepared.
Example 8: 65% Tolfenpyrad Fluopyram suspension concentrate (7:6)
Figure BDA0002065460490000083
The preparation method of the suspending agent comprises the following steps: the 65 percent of tolfenpyrad-fluopyram suspending agent can be prepared by mixing the materials in proportion, uniformly dispersing the mixture through high-speed shearing and sanding the mixture in a sand mill.
Second, indoor biological activity determination
1. Indoor toxicity determination of tolfenpyrad and fluopyram composition preparation on carrot root-knot nematode
Test subjects: root knot nematode disease of carrot
The test method comprises the following steps: the separation and preparation of soil nematodes adopts an improved Bellman funnel method to separate a sufficient number of nematodes from carrot planting soil, and the number of samples separated each time is more than 1000 to meet the test requirements. After fully shaking and mixing uniformly, the nematodes are concentrated to nematode liquid containing about 100 nematodes in each milliliter of water liquid for later use, the preparation of the nematode liquid is carried out the day before the treatment experiment, and the nematode liquid is stored in a refrigerator at 4 ℃ overnight. And (4) inspecting by using a stereoscope on the next day, and performing the test on the premise of ensuring that the survival rate of the nematodes is more than 90%, otherwise, performing the test after supplementing the number of the nematodes. Inoculating 2-year larvae of nematodes in 2-3 true leaf stages of carrots, adopting a root injection method, injecting 5ml of nematode inoculation liquid into rhizosphere soil, keeping 70-80% of humidity of the soil 24 hours after inoculation, and inoculating root-knot nematodes to the carrots for later use. The active ingredients of tolfenpyrad and fluopyram are prepared into mother liquor according to the proportioning requirement of the invention, and then the mother liquor is diluted to proper concentration by purified water for root irrigation treatment. After the treatment of the medicament, carrot seedlings are placed in an artificial climate chamber and then cultured for 80-90 days under the conditions of 10-20 ℃, 12h light-dark alternation and relative humidity of 60% -90%. Randomly investigating 4 pots each time, investigating 16 pots of carrot in total for each treatment, recording investigation result, calculating prevention effect, and calculating inhibition medium concentration LC by least square method50. According to the Sun Yunpei method, the synergistic effect of the mixed medicaments is evaluated according to the co-toxicity coefficient (CTC), namely that the CTC is less than or equal to 80 and is antagonistic, the CTC is more than 80 and less than 120 and is additive, the CTC is more than or equal to 120 and is synergistic, and the test results are shown in Table 1.
TABLE 1 indoor toxicity assay for carrot root knot nematode disease with tolfenpyrad and fluopyram combined preparation
Reagent for testing Proportioning EC50(μg/ml) Co-toxicity coefficient
Tolfenpyrad (A) --- 19.44 ---
Fluopyram (B) --- 3.17 ---
A:B 4:3 4.05 150.02
A:B 3:1 6.26 136.02
A:B 9:5 4.83 142.07
A:B 5:6 3.16 161.91
A:B 2:1 4.87 147.25
A:B 1:40 2.31 140.09
A:B 60:1 14.53 123.41
A:B 7:6 3.94 146.46
A:B 1:20 2.52 131.02
A:B 30:1 13.09 127.41
A:B 1:10 2.56 134.03
A:B 15:1 11.75 125.26
From the indoor toxicity measurement results in the table 1, it can be seen that both tolfenpyrad and fluopyram have an inhibition effect on carrot root-knot nematode, and when the weight ratio of tolfenpyrad to fluopyram is in the range of 1: 40-60: 1, the co-toxicity coefficient is greater than 120, which indicates that the tolfenpyrad and fluopyram combined preparation has a synergistic effect on carrot root-knot nematode, and particularly, when the weight ratio of tolfenpyrad to fluopyram is 5:6, the synergistic effect is more remarkable, and the co-toxicity coefficient is 161.91.
2. Indoor toxicity determination of tolfenpyrad and fluopyram composition preparation on phyllotreta striolata
Test subjects: phyllotreta striolata
The test method comprises the following steps: the test agents are prepared into the pharmaceutical compositions with different proportions according to the compounding range protected by the invention, and the pharmaceutical compositions are diluted into five concentration gradients on the basis of pre-experiments and stored for later use; taking a finger-shaped tube with two open ends, a diameter (d) of 3cm and a height (h) of 10cm, and placing 20 pieces of CO2Two ends of the anesthetized phyllotreta striolata adult are sealed by gauze and are firmly tied by rubber bands, and 4 repeated experiments are carried out on each treatment. 50mL of the prepared liquid medicine is respectively placed in 1L beakers and is kept in a water bath at 26 ℃ for 50r/min to-and-fro oscillation. Completely immersing 4 finger-shaped tubes treated in the same way into the liquid medicine to be tested at the same time, taking out after 30s, immediately picking all the test insects into a new dry finger-shaped tube with the same size by using a thin writing brush, placing 2 pieces of 5cm × 6cm single-layer paper towels and fresh cabbage leaves (d ═ 1.3cm) in the tube, sealing the tube by using gauze after all the test insects are picked, firmly binding the rubber bands, and soaking the test insects into a clear water solution in a contrast manner. And (4) calculating a result: after 48h, the number of dead insects was investigated, and the mortality and corrected mortality were calculated according to the Abbott formula. Determination of LC for test agents using DPS software50The values refer to pesticide test technology and evaluation method compiled by the yellow ocean, and an equivalent comparison method is adopted: LC to target when single agent50Value, LC to target after adding compound with built-up activity to the same agent50The value of the measured signal is compared with a predetermined value,LC if a built-up compound is added in the medicament50The value is smaller than that of the single medicament, and the synergistic effect is shown. Generally, a synergy index greater than 1 indicates synergy, less than 1 indicates antagonism, and 1 is additive, the test results are shown in table 1, and the magnitude of synergy is expressed by the synergy index:
the synergy index is LC when the medicament is singly used50LC of value/agent plus synergist50Value of
TABLE 2 indoor toxicity determination of tolfenpyrad and Fluopyram combination formulations for Phyllotreta striolata
Reagent for testing Proportioning LC50(μg/ml) Index of synergy
Tolfenpyrad (A) --- 125.53 ---
Fluopyram (B) --- 0 ---
A:B 4:3 109.16 1.15
A:B 3:1 102.06 1.23
A:B 9:5 110.11 1.14
A:B 5:6 123.07 1.02
A:B 2:1 125.17 1.09
A:B 1:40 123.07 1.02
A:B 60:1 113.09 1.11
A:B 7:6 119.55 1.05
A:B 1:20 124.29 1.01
A:B 30:1 108.22 1.16
A:B 1:10 118.42 1.06
A:B 15:1 112.08 1.12
From the indoor toxicity measurement results in the table 2 above, it can be seen that when the weight ratio of the fluopyram to the tolfenpyrad is in the range of 1: 40-60: 1, the synergy index is greater than 1, which indicates that the fluopyram and the tolfenpyrad are in the range and have synergistic effect.
Third, field test
1. Field efficacy test of tolfenpyrad and fluopyram combined preparation on phyllotreta striolata and carrot root knot nematode diseases
Test subjects: root knot nematode disease of phyllotreta striolata and carrot
The test method comprises the following steps: the experiment is arranged in a carrot land in Shandong Weifang city, the root-knot nematodes are harmful for years and are uniformly distributed and are often accompanied with the occurrence of yellow-curl striped flea beetles. The treatment agents adopted in the embodiments 1-4 of the invention are 30% of tolfenpyrad suspending agent and 41.7% of fluopyram suspending agent, clear water is used as a blank control, the application is carried out in the full period of harm of the root-knot nematodes and phyllotreta striolata, an irrigation method and a soil treatment method are adopted, liquid, powder and the like are used for treating the root-knot nematodes when the root-knot nematodes are attacked, water is added for root irrigation, and the granules are required to be applied in holes before the carrot seedlings are planted. Before application, the base number of nematode diseases of carrot seedlings and the base number of phyllotreta striolata larvae are investigated at five points of diagonal lines of each treatment area, and 10 carrots are investigated at each point. The control effect is investigated once in 7 days and 14 days after the pesticide application, the number of the nematode-affected plants and the base number of the yellow flea beetle larvae after the pesticide application are recorded, the control effect is calculated, and the test results are shown in table 3.
TABLE 3 field efficacy test of tolfenpyrad and Fluopyram combination formulations
Figure BDA0002065460490000121
As can be seen from the field efficacy test in Table 3, the combination preparation of tolfenpyrad and fluopyram has obviously improved effect of preventing and treating carrot root knot nematode and phyllotreta striolata compared with single activity, the dosage of the effective components is lower than the sum of the single components, but the prevention effect is improved, which shows that the compounding of tolfenpyrad and fluopyram has synergistic effect, in addition, the test agent of the invention is not found to cause phytotoxicity to crops, which shows that the preparation of the composition of the invention has better safety, and is worthy of popularization and application in production.
In light of the foregoing description of the preferred embodiment of the present invention, it is to be understood that various changes and modifications may be made by one skilled in the art without departing from the spirit and scope of the invention. The technical scope of the present invention is not limited to the content of the specification, and must be determined according to the scope of the claims.

Claims (2)

1. A pesticide composition containing tolfenpyrad and fluopyram is characterized in that: the active ingredients of the composition comprise tolfenpyrad and fluopyram, and the weight ratio of tolfenpyrad to fluopyram is 4:3, 3:1, 9:5 or 5: 6; the weight percentage of the sum of the weight of the tolfenpyrad and the weight of the fluopyram in the pesticide composition is 10 to 45 percent; the dosage forms of the composition are extruded granules, coated granules, wettable powder and microcapsule suspending agents.
2. Use of the pesticidal composition of claim 1 for preventing or controlling agricultural pests, which are meloidogyne carotovora and phyllotreta striolata.
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