CN113519534B - Insecticidal composition containing brofenbendiamide and flonicamid and application thereof - Google Patents
Insecticidal composition containing brofenbendiamide and flonicamid and application thereof Download PDFInfo
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- CN113519534B CN113519534B CN202110839873.1A CN202110839873A CN113519534B CN 113519534 B CN113519534 B CN 113519534B CN 202110839873 A CN202110839873 A CN 202110839873A CN 113519534 B CN113519534 B CN 113519534B
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- 239000005900 Flonicamid Substances 0.000 title claims abstract description 51
- 239000000203 mixture Substances 0.000 title claims abstract description 50
- RLQJEEJISHYWON-UHFFFAOYSA-N flonicamid Chemical compound FC(F)(F)C1=CC=NC=C1C(=O)NCC#N RLQJEEJISHYWON-UHFFFAOYSA-N 0.000 title claims abstract description 47
- 230000000749 insecticidal effect Effects 0.000 title claims abstract description 37
- 239000000575 pesticide Substances 0.000 claims abstract description 13
- 239000003795 chemical substances by application Substances 0.000 claims description 15
- 239000000375 suspending agent Substances 0.000 claims description 12
- 239000004480 active ingredient Substances 0.000 claims description 8
- 239000004615 ingredient Substances 0.000 claims description 8
- AMWBKZHMFJEZRP-UHFFFAOYSA-N 3-fluorobenzene-1,2-dicarboxamide Chemical compound NC(=O)C1=CC=CC(F)=C1C(N)=O AMWBKZHMFJEZRP-UHFFFAOYSA-N 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 239000004562 water dispersible granule Substances 0.000 claims description 5
- 241000008892 Cnaphalocrocis patnalis Species 0.000 claims description 4
- 239000005901 Flubendiamide Substances 0.000 claims description 4
- ZGNITFSDLCMLGI-UHFFFAOYSA-N flubendiamide Chemical compound CC1=CC(C(F)(C(F)(F)F)C(F)(F)F)=CC=C1NC(=O)C1=CC=CC(I)=C1C(=O)NC(C)(C)CS(C)(=O)=O ZGNITFSDLCMLGI-UHFFFAOYSA-N 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 239000007864 aqueous solution Substances 0.000 claims description 3
- 239000002552 dosage form Substances 0.000 claims description 3
- 239000000839 emulsion Substances 0.000 claims description 3
- 239000004530 micro-emulsion Substances 0.000 claims description 3
- 239000003094 microcapsule Substances 0.000 claims description 3
- 239000004563 wettable powder Substances 0.000 claims description 3
- 239000002518 antifoaming agent Substances 0.000 claims description 2
- 239000011230 binding agent Substances 0.000 claims description 2
- 239000002270 dispersing agent Substances 0.000 claims description 2
- 239000003995 emulsifying agent Substances 0.000 claims description 2
- 239000003960 organic solvent Substances 0.000 claims description 2
- 239000003755 preservative agent Substances 0.000 claims description 2
- 230000002335 preservative effect Effects 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims description 2
- 239000002562 thickening agent Substances 0.000 claims description 2
- 239000000080 wetting agent Substances 0.000 claims description 2
- 241000607479 Yersinia pestis Species 0.000 abstract description 16
- 235000007164 Oryza sativa Nutrition 0.000 abstract description 5
- 240000008042 Zea mays Species 0.000 abstract description 5
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract description 5
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract description 5
- 230000008901 benefit Effects 0.000 abstract description 5
- 235000005822 corn Nutrition 0.000 abstract description 5
- 235000009566 rice Nutrition 0.000 abstract description 5
- 208000003643 Callosities Diseases 0.000 abstract description 4
- 206010020649 Hyperkeratosis Diseases 0.000 abstract description 4
- 241001124076 Aphididae Species 0.000 abstract description 3
- 229920000742 Cotton Polymers 0.000 abstract description 3
- 239000005507 Diflufenican Substances 0.000 abstract description 3
- 241000255925 Diptera Species 0.000 abstract description 3
- 244000068988 Glycine max Species 0.000 abstract description 3
- 235000010469 Glycine max Nutrition 0.000 abstract description 3
- 244000299507 Gossypium hirsutum Species 0.000 abstract description 3
- 244000061456 Solanum tuberosum Species 0.000 abstract description 3
- 235000002595 Solanum tuberosum Nutrition 0.000 abstract description 3
- 230000001055 chewing effect Effects 0.000 abstract description 3
- WYEHFWKAOXOVJD-UHFFFAOYSA-N diflufenican Chemical compound FC1=CC(F)=CC=C1NC(=O)C1=CC=CN=C1OC1=CC=CC(C(F)(F)F)=C1 WYEHFWKAOXOVJD-UHFFFAOYSA-N 0.000 abstract description 3
- 244000037666 field crops Species 0.000 abstract description 3
- 235000012015 potatoes Nutrition 0.000 abstract description 3
- 238000002360 preparation method Methods 0.000 abstract description 3
- 241000196324 Embryophyta Species 0.000 abstract description 2
- 241000256602 Isoptera Species 0.000 abstract description 2
- 244000046052 Phaseolus vulgaris Species 0.000 abstract description 2
- 235000010627 Phaseolus vulgaris Nutrition 0.000 abstract description 2
- 241001414989 Thysanoptera Species 0.000 abstract description 2
- 235000021307 Triticum Nutrition 0.000 abstract description 2
- 244000098338 Triticum aestivum Species 0.000 abstract description 2
- 238000012271 agricultural production Methods 0.000 abstract description 2
- FTQWRYSLUYAIRQ-UHFFFAOYSA-N n-[(octadecanoylamino)methyl]octadecanamide Chemical compound CCCCCCCCCCCCCCCCCC(=O)NCNC(=O)CCCCCCCCCCCCCCCCC FTQWRYSLUYAIRQ-UHFFFAOYSA-N 0.000 abstract description 2
- 241000254173 Coleoptera Species 0.000 abstract 1
- 241000255777 Lepidoptera Species 0.000 abstract 1
- 240000007594 Oryza sativa Species 0.000 abstract 1
- 230000002085 persistent effect Effects 0.000 abstract 1
- 241000238631 Hexapoda Species 0.000 description 16
- 238000012360 testing method Methods 0.000 description 15
- 230000002195 synergetic effect Effects 0.000 description 8
- 230000001276 controlling effect Effects 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 239000002917 insecticide Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 230000009471 action Effects 0.000 description 5
- 230000001018 virulence Effects 0.000 description 5
- 241000209094 Oryza Species 0.000 description 4
- 231100000419 toxicity Toxicity 0.000 description 4
- 230000001988 toxicity Effects 0.000 description 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 238000013329 compounding Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000003912 environmental pollution Methods 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 239000005886 Chlorantraniliprole Substances 0.000 description 2
- 241000098289 Cnaphalocrocis medinalis Species 0.000 description 2
- SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 description 2
- 238000004166 bioassay Methods 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- PSOVNZZNOMJUBI-UHFFFAOYSA-N chlorantraniliprole Chemical compound CNC(=O)C1=CC(Cl)=CC(C)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl PSOVNZZNOMJUBI-UHFFFAOYSA-N 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000013530 defoamer Substances 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- -1 neonicotinoids Substances 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000012865 response to insecticide Effects 0.000 description 2
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 2
- 235000010234 sodium benzoate Nutrition 0.000 description 2
- 239000004299 sodium benzoate Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000000230 xanthan gum Substances 0.000 description 2
- 235000010493 xanthan gum Nutrition 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- 229940082509 xanthan gum Drugs 0.000 description 2
- 206010001497 Agitation Diseases 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 241000254127 Bemisia tabaci Species 0.000 description 1
- 241001674044 Blattodea Species 0.000 description 1
- 241000426497 Chilo suppressalis Species 0.000 description 1
- 108010062745 Chloride Channels Proteins 0.000 description 1
- 102000011045 Chloride Channels Human genes 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 241000238424 Crustacea Species 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241000257303 Hymenoptera Species 0.000 description 1
- 241000594031 Liriomyza sativae Species 0.000 description 1
- 241000244206 Nematoda Species 0.000 description 1
- 206010029350 Neurotoxicity Diseases 0.000 description 1
- 241000500441 Plutellidae Species 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000005925 Pymetrozine Substances 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 241000256247 Spodoptera exigua Species 0.000 description 1
- 206010044221 Toxic encephalopathy Diseases 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000003905 agrochemical Substances 0.000 description 1
- 230000003281 allosteric effect Effects 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000001887 anti-feedant effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- QSLZKWPYTWEWHC-UHFFFAOYSA-N broflanilide Chemical compound C=1C=CC(C(=O)NC=2C(=CC(=CC=2Br)C(F)(C(F)(F)F)C(F)(F)F)C(F)(F)F)=C(F)C=1N(C)C(=O)C1=CC=CC=C1 QSLZKWPYTWEWHC-UHFFFAOYSA-N 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000012447 hatching Effects 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000007135 neurotoxicity Effects 0.000 description 1
- 231100000228 neurotoxicity Toxicity 0.000 description 1
- 229960002715 nicotine Drugs 0.000 description 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
- 230000000361 pesticidal effect Effects 0.000 description 1
- IBBMAWULFFBRKK-UHFFFAOYSA-N picolinamide Chemical compound NC(=O)C1=CC=CC=N1 IBBMAWULFFBRKK-UHFFFAOYSA-N 0.000 description 1
- 229920005646 polycarboxylate Polymers 0.000 description 1
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- QHMTXANCGGJZRX-WUXMJOGZSA-N pymetrozine Chemical compound C1C(C)=NNC(=O)N1\N=C\C1=CC=CN=C1 QHMTXANCGGJZRX-WUXMJOGZSA-N 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
- 229920005552 sodium lignosulfonate Polymers 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 239000004557 technical material Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to an insecticidal composition containing bromofenoxaprop-p-fluorobenzene bisamide and flonicamid and application thereof, and belongs to the technical field of pesticide insecticidal compositions. The insecticidal composition comprises the brotrochan diflufenican and flonicamid in a weight ratio of 1: 1-50. The insecticidal composition can effectively control various chewing and piercing-sucking mouthpart pests, such as lepidoptera, coleoptera, termite, aphididae, thrips, mosquitoes and flies and the like, and is suitable for leafy and fruiting plants, potatoes, soybeans, cotton, corns and beans, and various field crops such as rice, wheat, corns and the like. Compared with the existing single preparation, the composition provided by the invention has the advantages that the insecticidal effect is obviously improved, the persistent period is long, the composition is safe to crops, and the composition is worthy of popularization and application in agricultural production.
Description
Technical Field
The disclosure relates to the technical field of pesticides, and particularly relates to an insecticidal composition containing bromofenoxanil and flonicamid and application thereof in pest control.
Background
Bromofenoxanil, english name: the molecular structure of Broflanilide is as follows:
is a bisamide insecticide developed by Mitsui agricultural chemical company, and the brofenpyrad fluorobenzene bisamide is an insecticide with a novel action mechanism: GABA-gated chloride channel allosteric modulators. It can cause hyperexcitability and convulsions in insects. Brofenpyrad fluorobenzenediamide was classified by the Insecticide Resistance Action Committee (IRAC) into group 30, which was the only compound in this group to date. Bromoidin fluorobenzenediamide is useful in Insecticide Resistance Management (IRM) applications to control pests resistant to existing insecticides, and exhibits excellent effectiveness in controlling a wide variety of problematic chewing pests, including caterpillars and crustaceans that infest specialty and row crops, as well as non-crop pests such as termites, ants, cockroaches, and flies. It also has potential use in cereals as a seed treatment for nematode control and also on foliar surfaces for leafy and fruiting plants, potatoes, soybeans, cotton, corn and legumes.
Flonicamid, english name: flonicamid, molecular structure:
the insecticidal composition is a novel low-toxicity pyridine amide type insect growth regulating insecticide developed by Nippon Shigaku K.K., wherein flonicamid molecules contain trifluoromethyl and introduce a nicotine amine structure, and the flonicamid has strong neurotoxicity and quick antifeedant effect, has a unique action mechanism and is different from high-efficiency insecticides such as neonicotinoids, pymetrozine and the like. The biological activity of the pesticide is extremely high, and the pesticide can be used for preventing and controlling aphids and other sucking mouthparts pests on wide crops and can also be used for preventing and controlling pests which have resistance to conventional pesticides. Has good safety to crops, people, livestock and environment and has good development prospect.
The long-term use of the pesticide containing the single active ingredient for pest control can bring about different degrees of harm, such as generation of drug resistance of pests, environmental pollution and the like. The insecticide composition can be used for reasonably compounding different active ingredients, and has the effects of expanding an insecticidal spectrum, delaying the duration time and reducing the dosage, so that the medication cost is reduced and the environmental pollution is reduced.
Disclosure of Invention
In order to overcome the problems that a single pesticide in the prior art is easy to generate resistance after being used for a long time, the effect of preventing and controlling pests is reduced, the use amount is increased, the environmental pollution is caused and the like, the disclosure provides a pesticidal composition containing brofenbendiamide and flonicamid and application thereof.
In one aspect, the invention provides an insecticidal composition containing brotrochar bendiamide and flonicamid, which contains active ingredients, wherein the active ingredients are brotrochar bendiamide and flonicamid. Preferably, the weight ratio of the flubendiamide to the flonicamid in the insecticidal composition is 1: 1-50.
Further, the weight ratio of the flubendiamide to the flonicamid in the insecticidal composition is 1: 1-30.
Preferably, the weight ratio of the flubendiamide to the flonicamid in the insecticidal composition is 1:1 to 10, particularly preferably in a ratio of 1: 40,1: 30,1: 20,1: 10,1: 7,1: 4,1: 2,1: 1.
on the other hand, the insecticidal composition of the invention also comprises auxiliary components, and the content of the auxiliary components is 1-90 parts by weight relative to 1 part by weight of the active components; preferably, the content of the auxiliary ingredient is 15 to 80 parts by weight with respect to 1 part by weight of the active ingredient.
Further, the auxiliary ingredients in the insecticidal composition comprise at least one of an emulsifier, a wetting agent, a dispersing agent, a thickening agent, an antifreezing agent, a preservative, a wall material, a film forming agent, a color paste, a defoaming agent, water, an organic solvent, a disintegrating agent, a binder and a solid inert carrier.
Preferably, the formulation of the insecticidal composition provided by the invention is suspending agent, missible oil, oil suspending agent, microemulsion, emulsion in water, microcapsule suspending agent, aqueous solution, wettable powder, water dispersible granule or seed treatment agent.
On the other hand, the invention also provides an application of the insecticidal composition, which is used for preparing a pesticide preparation for preventing and controlling pests, and can be used for preventing and controlling pests on crops such as fruits, vegetables, fields and the like, in particular chewing mouthparts pests such as diamond back moths, beet armyworms, chilo suppressalis, rice leaf rollers and the like, and piercing-sucking mouthparts pests such as liriomyza sativae, thrips, bemisia tabaci and aphids. The field crops refer to potatoes, soybeans, cotton, corns and beans, and various field crops such as rice, wheat, corns and the like.
Compared with the prior art, the invention has the beneficial effects that:
the insecticidal composition containing the brotroche difluoride and the flonicamid has the advantages that the effective components of the brotroche difluoride and the flonicamid are combined, and the two pesticides have obvious synergistic effect.
Compared with the existing single-component pesticide, the insecticidal composition containing the brotroche difluoride and the flonicamid has an obvious insecticidal effect and a synergistic effect, and meanwhile, the insecticidal composition containing the brotroche difluoride and the flonicamid is safe to crops and worthy of popularization and application in agricultural production.
Detailed Description
The present invention will be further described with reference to the following examples.
The instruments, reagents, materials and the like used in the following examples are conventional instruments, reagents, materials and the like in the prior art and are commercially available in a normal manner unless otherwise specified. Unless otherwise specified, the experimental methods, detection methods, and the like described in the following examples are conventional experimental methods, detection methods, and the like in the prior art.
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described with the following embodiments, but the present invention is by no means limited to these examples. The following description is only a preferred embodiment of the present invention, and is only for the purpose of explaining the present invention, and should not be construed as limiting the scope of the present invention. It should be understood that any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
The insecticidal composition can be prepared into any one of dosage forms suitable for agriculture by using a known method, and the better dosage forms are suspending agents, missible oil, oil suspending agents, micro-emulsions, aqueous emulsions, microcapsule suspending agents, aqueous solutions, wettable powder, water dispersible granules or seed treatment agents; all the percentages in the formula are weight percentages, the processing technology of various formulations of the composition is the prior art, and the composition can be changed according to different conditions. The present invention will be further described with reference to the following examples.
Example 1: 40% Chlorantraniliprole, flonicamid suspension (1:7)
The 40% brofenbendiamide-flonicamid suspending agent comprises the following components in parts by weight:
5 wt% of brobendiamide, 35 wt% of flonicamid, 4 wt% of polycarboxylate, 3 wt% of polyoxyethylene polyoxypropylene copolymer, 0.2 wt% of xanthan gum, 0.2 wt% of sodium benzoate, 0.3 wt% of magnesium aluminum silicate, 0.3 wt% of silicone defoamer, 5 wt% of propylene glycol, and water added to 100 wt%.
Example 2: 26% Chlorantraniliprole, flonicamid suspension (1:25)
26% of a bromofenoxaprop-fluorobenzene bisamide-flonicamid suspending agent, wherein the suspending agent comprises the following components in parts by weight:
1 wt% of bromofenoxanil, 25 wt% of flonicamid, 2.5 wt% of alkylphenol polyoxyethylene, 2 wt% of sodium dodecyl sulfate, 0.3 wt% of xanthan gum, 0.3 wt% of sodium benzoate, 0.5 wt% of magnesium aluminum silicate, 0.3 wt% of silicone defoamer, 5 wt% of ethylene glycol, and water added to 100 wt%.
Example 3: 51% brobendiamide-flonicamid water dispersible granule (1:50)
51% brofenbendiamide-flonicamid water dispersible granules, which comprise the following components in parts by weight:
1 wt% of bromofenoxanil, 50 wt% of flonicamid, 6 wt% of sodium dodecyl benzene sulfonate, 8 wt% of sodium lignosulfonate, 15 wt% of dextrin and kaolin added to 100 wt%.
The insecticidal composition comprises the effective components of the brotrochar diflufenican and the flonicamid, and the combination of the two has obvious synergistic effect on insect pest control, not only simple superposition of the effects of the two agents, which can be clearly understood from the following test results.
The inventor carries out synergistic research on mutual compounding of the insecticidal composition of the brobendiamide and the flonicamid. The test adopts rice leaf roller as a test object, and if no special description is given, the following mentioned proportions (including percentage) are weight ratio, and the specific method is as follows:
indoor bioassay screening
1.1 test pests:
the rice leaf roller imagoes bred on rice leaves in a greenhouse are inoculated on rice sprouts growing without insects, spawning and hatching are carried out in an insect breeding room with the indoor temperature of 28 +/-2 ℃, the relative humidity of 55-65% and illumination for 12 hours, and the larvae are bred by the rice leaves until the larvae grow to 3 years old for later use.
1.2 test agent:
98% of bromofenoxaprop-p-fluorobenzamide technical material (AGRO, Mitsui chemical Co., Ltd.) and 96% of flonicamid (Takara Shuzo Co., Ltd.).
1.3 test methods:
referring to the dropping method of the bioassay standard NY/T1154.1-2006, a micro dropper is cleaned by a solvent, and the dropper is adjusted to a standby state. Selecting indoor-fed 3-instar larvae as test insects, and placing the test insects in a 9cm culture dish for later use under mild anesthesia. Dripping the liquid medicine on the forebreast and back plate of the tested insect head by using a micro dropper, wherein 0.5 mu L of liquid medicine is dripped into each head. Transferring the spotted test insects to normal conditions for feeding. Each treatment was repeated 4 times, with no less than 10 test insects per repetition.
1.4 data statistics and analysis:
and (5) checking the death condition of the test insects 24h after treatment, calculating the death rate (taking the non-autonomous reaction of the test insects after light needling as a standard for judging the death of the test insects), and recording the total number of the test insects and the number of dead insects.
From the survey data, corrected mortality for each treatment was calculated. And the co-toxicity coefficient (CTC value) of the mixture was calculated by Sun cloud Peter method with reference to NY/T1154.7-2006.
The corrected mortality is calculated according to the formulas (1) and (2) in percentage (%), and the calculation result retains two digits after decimal point:
in the formula:
P1-mortality;
k- - -number of dead insects;
n- - -total number of worms treated.
In the formula:
P2corrected mortality;
Pt-treatment mortality;
P0mortality of blank control.
If the control mortality rate is less than 5%, not correcting; correcting the control mortality rate between 5% and 20% according to a formula (2); control mortality was > 20%, and the test was redone.
By taking the logarithmic value of the medicament concentration (mg/L) as an independent variable X and the probability value of correcting the death rate as a dependent variable Y, respectively establishing toxicity regression equations, calculating LC50 of single-dose and mixed-dose and co-toxicity coefficients of the mixed-dose by adopting DPS software, and comparing the synergistic conditions. LC50 was calculated to calculate the cotoxicity coefficient (CTC) according to the grandsinope method. The co-toxicity coefficient CTC is calculated according to the following formula:
(A is brotrochar difluoride as a standard medicament, the virulence index is 100, B is flonicamid): the statistical analysis was performed using the DPS statistical analysis software, LC50 was calculated for each drug, and the cotoxicity coefficient (CTC value) of the blend was calculated according to the Sun cloud Peel method.
The virulence index (ATI) was measured as (standard agent LC 50/test agent LC50) × 100.
Theoretical virulence index (TTI) ═ a agent virulence index x percent of a in the mixture + B agent virulence index x percent of B in the mixture.
Co-toxicity coefficient (CTC) × 100 [ measured toxicity index (ATI) of the mixture)/Theoretical Toxicity Index (TTI) of the mixture ].
According to NY/T11547.7-2006 pesticide combination division standard: the co-toxicity coefficient (CTC) is more than or equal to 120, which is the synergistic effect; the co-toxicity coefficient (CTC) is less than or equal to 80, and the antagonism is shown; 80 < co-toxicity coefficient (CTC) < 120 showed additive effects. The results are shown in Table 1.
TABLE 1 measurement of indoor combined toxicity of Bifenflurdiamide and flonicamid for cnaphalocrocis medinalis
As can be seen from table 1, when the brotrocha bendiamide and the flonicamid are compounded in the mixing ratio of 1:1-50 (mass ratio), the cotoxicity coefficient (CTC) is greater than 120 (especially 1:7), and a synergistic effect is shown on cnaphalocrocis medinalis, so that the reasonability and feasibility of compounding the brotrocha bendiamide and the flonicamid are seen.
In conclusion, the invention adopts the compound composition of two active ingredients, namely the brotrochar diflufenican and the flonicamid, and has a synergistic effect. Compared with single preparation, the insecticidal composition has the advantages of unique action mechanism, small dosage, good quick action, long lasting period and environmental protection. Therefore, the research and the development and the popularization of the invention have great social significance and can generate great economic benefits.
Claims (8)
1. The insecticidal composition is characterized by comprising an active pesticide ingredient, wherein the active pesticide ingredient is brobendiamide and flonicamid, and the weight ratio of the brobendiamide to the flonicamid is 1: 1-50.
2. The insecticidal composition containing the flonicamid and the flonicamid as claimed in claim 1, wherein the weight ratio of the flonicamid to the flonicamid is 1: 1-30.
3. The insecticidal composition containing the flonicamid and the flonicamid as claimed in claim 2, wherein the weight ratio of the flonicamid to the flonicamid is 1: 1-10.
4. The insecticidal composition containing the brevibrambutan fluorobenzodiamide and the flonicamid as claimed in any one of claims 1 to 3, wherein the insecticidal composition further comprises an auxiliary ingredient, and the content of the auxiliary ingredient is 1 to 90 parts by weight relative to 1 part by weight of the active ingredient.
5. The insecticidal composition containing flubendiamide and flonicamid as claimed in claim 4, wherein the content of the auxiliary ingredient is 15-80 parts by weight with respect to 1 part by weight of the active ingredient.
6. The insecticidal composition containing the brevibrambutan fluorobenzene bisamide and the flonicamid as claimed in claim 5, wherein the auxiliary ingredients comprise at least one of an emulsifier, a wetting agent, a dispersing agent, a thickening agent, an antifreezing agent, a preservative, a wall material, a film forming agent, a color paste, an antifoaming agent, water, an organic solvent, a disintegrating agent, a binder and a solid inert carrier.
7. The insecticidal composition containing the brevibrambutan fluorobenzene bisamide and the flonicamid as claimed in claim 6, wherein the dosage form of the insecticidal composition is suspending agent, missible oil, oil suspending agent, microemulsion, aqueous emulsion, microcapsule suspending agent, aqueous solution, wettable powder, water dispersible granule or seed treatment agent.
8. The application of the insecticidal composition containing the brotrochar benserdiamide and the flonicamid as claimed in any one of claims 1 to 7, which is characterized in that the insecticidal composition is used for preventing and controlling rice leaf rollers.
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